ru 38882 profile

Cross-References

ID Source	ID
PubMed CID	6917958
CHEMBL ID	2107564
SCHEMBL ID	187571
MeSH ID	M0125124

Synonyms (24)

Synonym
ru-882
ru-38882
inocoterone acetate
83646-86-0
inocoterone acetate (usan)
D04538
[(3s,3as,9as,9bs)-6-ethyl-3a-methyl-7-oxo-2,3,4,5,8,9,9a,9b-octahydro-1h-cyclopenta[a]naphthalen-3-yl] acetate
inocoterone acetate [usan]
7h-benz(e)inden-7-one, 3-(acetyloxy)-6-ethyl-1,2,3,3a,4,5,8,9,9a,9b-decahydro-3a-methyl-, (3s-(3alpha,3aalpha,9aalpha,9bbeta))-
17beta-hydroxy-2,5-seco-a-dinorestr-9-en-5-one acetate
onu02d116s ,
unii-onu02d116s
ru 38882
ru 882
CHEMBL2107564
SCHEMBL187571
7h-benz(e)inden-7-one, 3-(acetyloxy)-6-ethyl-1,2,3,3a,4,5,8,9,9a,9b-decahydro-3a-methyl-, (3s-(3.alpha.,3a.alpha.,9a.alpha.,9b.beta.))-
ino-coterone acetate
(3s,3as,9as,9bs)-6-ethyl-3a-methyl-7-oxo-2,3,3a,4,5,7,8,9,9a,9b-decahydro-1h-cyclopenta[a]naphthalen-3-yl acetate
Q27285754
DTXSID401003615
(3s,3as,9as,9bs)-3-(acetyloxy)-6-ethyl-1,2,3,3a,4,5,8,9,9a,9b-decahydro-3a-methyl-7h-benz[e]inden-7-one
7h-benz[e]inden-7-one, 3-(acetyloxy)-6-ethyl-1,2,3,3a,4,5,8,9,9a,9b-decahydro-3a-methyl-, (3s,3as,9as,9bs)-
AKOS040746923

Research Excerpts

Overview

RU 38882 is a new antiandrogen.

Excerpt	Reference	Relevance
"RU 38882 is a new antiandrogen. "	( Effect of a new topically active antiandrogen (RU 38882) on the rat sebaceous gland: comparison with cyproterone acetate. Bouton, MM; Lecaque, D; Secchi, J; Tournemine, C, 1986)	1.97

[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (6)

Timeframe	Studies, This Drug (%)	All Drugs %
pre-1990	3 (50.00)	18.7374
1990's	3 (50.00)	18.2507
2000's	0 (0.00)	29.6817
2010's	0 (0.00)	24.3611
2020's	0 (0.00)	2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.37

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

Metric	This Compound (vs All)
Research Demand Index	12.37 (24.57)
Research Supply Index	2.08 (2.92)
Research Growth Index	4.45 (4.65)
Search Engine Demand Index	0.00 (26.88)
Search Engine Supply Index	0.00 (0.95)

This Compound (12.37)

All Compounds (24.57)

Study Types

Publication Type	This drug (%)	All Drugs (%)
Trials	1 (16.67%)	5.53%
Reviews	0 (0.00%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	5 (83.33%)	84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Substance	Relationship Strength	Studies	Classes	Roles
cyproterone acetate [no description available]	7.66	3	20-oxo steroid; 3-oxo-Delta(4) steroid; acetate ester; chlorinated steroid; steroid ester	androgen antagonist; geroprotector; progestin
4-(3,4,4-trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile 4-(3,4,4-trimethyl-5-oxo-2-thioxo-1-imidazolidinyl)-2-(trifluoromethyl)benzonitrile: a non-steroidal antiandrogen; structure given in first source	1.98	1
ru 58841 [no description available]	1.98	1
cyproterone Cyproterone: An anti-androgen that, in the form of its acetate (CYPROTERONE ACETATE), also has progestational properties. It is used in the treatment of hypersexuality in males, as a palliative in prostatic carcinoma, and, in combination with estrogen, for the therapy of severe acne and hirsutism in females.	7.37	2	17alpha-hydroxy steroid; 20-oxo steroid; 3-oxo-Delta(4) steroid; chlorinated steroid; tertiary alpha-hydroxy ketone	androgen antagonist

Condition	Indicated	Relationship Strength	Studies	Trials
Acne [description not available]	0	3.77	2	1
Acne Vulgaris A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.	0	3.77	2	1

ru 38882