azelaic acid has been researched along with Acne in 100 studies
nonanedioic acid : An alpha,omega-dicarboxylic acid that is heptane substituted at positions 1 and 7 by carboxy groups.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This review is an update of the literature accumulated over the past 6 years following the original observation that topically applied azelaic acid, a non-toxic C9 dicarboxylic acid, has a beneficial therapeutic effect on acne vulgaris." | 10.16 | [Azelaic acid in the treatment of acne]. ( Breathnach, AS; Nazzaro-Porro, M; Passi, S; Picardo, M; Zina, G, 1989) |
| "Evaluate the efficacy and tolerance of the test product containing Myrtus communis extract and azelaic acid compared with a light moisturizing cream (LCM) in adult females in the acne maintenance phase." | 9.69 | The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study. ( Andrade, LSM; Bacquey, A; Bagatin, E; Baradat, S; Lauze, C; Mengeaud, V; Miot, HA; Rocha, MA; Soares, JLM; Thouvenin, MD, 2023) |
| "Topical azelaic acid (AA) is indicated for acne and rosacea, but there is some evidence for its use for other dermatological conditions." | 9.41 | A systematic review to evaluate the efficacy of azelaic acid in the management of acne, rosacea, melasma and skin aging. ( Campbell, J; Daly, ML; King, S; Maybury, C; Moncrieff, G; Rowe, R, 2023) |
| " This study aims to explore the differences in the effectiveness of azelaic and pyruvic acid peels in the treatment of acne vulgaris." | 9.34 | A comparison of the effectiveness of azelaic and pyruvic acid peels in the treatment of female adult acne: a randomized controlled trial. ( Chilicka, K; Dzieńdziora-Urbińska, I; Rogowska, AM; Szyguła, R; Taradaj, J, 2020) |
| " Azelaic acid cream has been previously approved for acne vulgaris, thus azelaic acid foam may be a viable treatment option for truncal acne." | 9.24 | The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Truncal Acne Vulgaris. ( Del Rosso, JQ; Hoffman, LK; Kircik, LH, 2017) |
| "Treatment with azelaic acid 20 % cream significantly improves acne severity and disease-related QoL in adult women." | 9.22 | Azelaic acid 20 % cream: effects on quality of life and disease severity in adult female acne patients. ( Auer-Grumbach, P; Berghammer, G; Kainz, JT; Lackner, V; Perl-Convalexius, S; Popa, R; Wolfesberger, B, 2016) |
| "To compare the efficacy, tolerability and safety of a combination of benzoyl peroxide 3% and clindamycin 1% (BPO + CLN) with azelaic acid 20% (AzA) for the topical treatment of mild-to-moderate acne vulgaris." | 9.22 | A multicentre, randomized, single-blind, parallel-group study comparing the efficacy and tolerability of benzoyl peroxide 3%/clindamycin 1% with azelaic acid 20% in the topical treatment of mild-to-moderate acne vulgaris. ( Hennig, M; Ress, C; Schaller, M; Sebastian, M; Seidel, D, 2016) |
| "Azelaic acid gel is an effective topical monotherapy for mild-to-moderate acne vulgaris; its new gel form is an enrichment of acne therapy." | 9.11 | [Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies]. ( Gollnick, HP; Graupe, K; Zaumseil, RP, 2004) |
| "20% azelaic acid cream was compared clinically with it vehicle in a 3-month double-blind study of 92 patients with moderate inflammatory acne." | 9.06 | Clinical studies of 20% azelaic acid cream in the treatment of acne vulgaris. Comparison with vehicle and topical tretinoin. ( Graupe, K; Katsambas, A; Stratigos, J, 1989) |
| "In a series of investigations using 20% azelaic acid cream as a therapy for acne, it was found that the treatment, compared with its placebo, significantly reduced inflamed lesions after 1 month and non-inflamed lesions after 2 months." | 9.06 | Clinical and laboratory studies on treatment with 20% azelaic acid cream for acne. ( Cunliffe, WJ; Holland, KT, 1989) |
| "20% azelaic acid cream was compared clinically with its vehicle in a 3-month double-blind study of 92 patients with moderate inflammatory acne." | 9.06 | [National and international clinical experiences with azelaic acid cream in the treatment of comedo acne]. ( Giannotti, B, 1989) |
| "In a series of investigation using 20% azelaic acid as a therapy for acne, it was found that the treatment, compared with most common therapies (benzoylperoxide, oral tetracycline) significantly reduced inflamed lesions in papulo-pustular acne." | 9.06 | [National and international experiences with azelaic acid cream in the treatment of papulo-pustular acne]. ( Caputo, R; Cavicchini, S, 1989) |
| "Preliminary clinical studies (2) proved the effectiveness of topical azelaic acid (AZA) in the treatment of acne vulgaris." | 9.06 | Long-term treatment of acne with 20% azelaic acid cream. ( Caputo, R; Cavicchini, S, 1989) |
| "Topical azelaic acid and oral tetracycline were compared in a 6-month double-blind study for treatment of acne vulgaris in 45 male subjects with clinical acne." | 9.06 | Topical azelaic acid and the treatment of acne: a clinical and laboratory comparison with oral tetracycline. ( Bladon, PT; Burke, BM; Cunliffe, WJ; Forster, RA; Holland, KT; King, K, 1986) |
| "To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha-hydroxy acid, and sulphur) for acne." | 9.05 | Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020) |
| " In terms of treatment response (measured using participants' global self-assessment of acne improvement, PGA), azelaic acid was probably less effective than benzoyl peroxide (RR = 0." | 9.05 | Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. ( Liu, G; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020) |
| " Retinoids and azelaic acid have been widely used to treat acne." | 8.89 | Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color. ( Doig, S; Keri, J; Woolery-Lloyd, HC, 2013) |
| "Benzoyl peroxide was introduced as a basic treatment already in acne therapy 1934." | 8.86 | [Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy]. ( Degitz, K; Fluhr, JW, 2010) |
| "Azelaic acid (AzA) 15% gel is approved for the treatment of rosacea in the US, but also has approval for the treatment of acne vulgaris in many European countries where it has demonstrated success." | 8.84 | Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris. ( Thiboutot, D, 2008) |
| "Benzoyl peroxide (BPO) was introduced in the treatment of acne in 1934." | 8.83 | [Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid]. ( Fluhr, JW; Worret, WI, 2006) |
| "Azelaic acid 20% cream (AZELEX) is a novel anti-acne agent with antimicrobial activity and keratinization-normalizing properties." | 8.79 | Azelaic acid 20% cream (AZELEX) and the medical management of acne vulgaris. ( Gibson, JR, 1997) |
| "Azelaic acid is another option for the topical treatment of mild to moderate inflammatory acne vulgaris." | 8.79 | Azelaic acid therapy for acne. ( Mackrides, PS; Shaughnessy, AF, 1996) |
| "Azelaic acid is a naturally occurring saturated dicarboxylic acid which, on topical application (usually as a 20% cream), has been shown to be effective in the treatment of comedonal acne and inflammatory (papulopustular, nodular and nodulocystic) acne, as well as various cutaneous hyperpigmentary disorders characterised by hyperactive/abnormal melanocyte function, including melasma and, possibly, lentigo maligna." | 8.78 | Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. ( Fitton, A; Goa, KL, 1991) |
| "The current work was aimed at the development of a topical drug delivery system for azelaic acid (AzA) for acne treatment." | 8.31 | The Formulation and Evaluation of Deep Eutectic Vehicles for the Topical Delivery of Azelaic Acid for Acne Treatment. ( Al-Adham, I; Al-Akayleh, F; Al-Ani, I; Al-Remawi, M; Ali, HHM; Khanfar, M; Luhaibi, DK; Nasereddin, J; Qinna, NA; Shalan, N, 2023) |
| "Azelaic acid (AzA) is a USFDA bioactive prescribed against acne vulgaris." | 8.12 | Hydrogel composite containing azelaic acid and tea tree essential oil as a therapeutic strategy for Propionibacterium and testosterone-induced acne. ( Aljabali, AAA; Bakshi, HA; Bisht, A; Chakraborty, A; Chellappan, DK; Dev, K; Dhiman, T; Dua, K; Gupta, G; Hemrajani, C; Negi, P; Nidhi, P; Rathore, C; Rolta, R; Sourirajan, A; Tambuwala, MM; Upadhyay, N, 2022) |
| "In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris." | 8.12 | Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: formulation, characterization, ( Arpa, MD; Erim, ÜC; Hoş, A; Seçen, İM; Üstündağ Okur, N, 2022) |
| "To overcome the poor solubility, skin irritation, and low permeability of azelaic acid (AZA) existed on the marketed formulations, a co-drug principle via matrine (MAT) was adopted to prepare anti-acne dissolving microneedles (DMNs)." | 8.02 | Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine. ( Gao, Y; Xing, M; Yang, G; Zhang, S, 2021) |
| " Chemical peeling is a well-known option in the treatment of acne vulgaris, but little is known about azelaic acid (AZA) peels." | 8.02 | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne. ( Budzisz, E; Erkiert-Polguj, A; Szymańska, A, 2021) |
| "To examine the efficacy and safety of azelaic acid 15% foam in the treatment of moderate-to-severe facial acne Methods: Twenty subjects with moderate-to-severe facial acne vulgaris were enrolled in this two-center, open-label pilot study." | 7.88 | The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris. ( Chen, T; Harper, JC; Hashim, PW; Kircik, LH, 2018) |
| "Azelaic acid (AzA) is used in the treatment of acne." | 7.79 | Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. ( Ascensão, L; Baptista, M; Candeias, S; Gomes, A; Martinho, N; Pinto, P; Reis, CP; Rijo, P, 2013) |
| "Thirty patients of either sex (23 M, 7 F) ranging in age between 16 and 36 years, affected of acne vulgaris, were given 20% azelaic acid cream over a period of 6 months." | 7.67 | [Topical therapeutic action of azelaic acid in polymorphous acne]. ( Florio, T; Petruzzellis, V; Troccoli, T, 1989) |
| "Patients treated with azelaic acid (15%) cream for chloasma reported simultaneous improvement of acne lesions within the treated areas." | 7.66 | Beneficial effect of 15% azelaic acid cream on acne vulgaris. ( Breathnach, A; Clayton, R; Nazzaro-Porro, M; Passi, S; Picardo, M; Zina, G, 1983) |
| "AzA15% gel is a safe and effective treatment and maintenance treatment of female adult acne with non-inferior efficacy to AD 0." | 6.80 | A randomized investigator-blind parallel-group study to assess efficacy and safety of azelaic acid 15% gel vs. adapalene 0.1% gel in the treatment and maintenance treatment of female adult acne. ( Gollnick, H; Kropf, S; Lux, A; Papakonstantinou, E; Thielitz, A; Wiede, A, 2015) |
| "Acne vulgaris is a common problem, particularly among adolescents, which is usually resistant to monotherapy." | 6.75 | Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris. ( Ajami, M; Babakoohi, S; Firooz, A; Habibey, R; Nassiri-Kashani, M; Pazoki-Toroudi, H; Rahshenas, M; Shizarpour, M; Tabatabaie, H, 2010) |
| "This review is an update of the literature accumulated over the past 6 years following the original observation that topically applied azelaic acid, a non-toxic C9 dicarboxylic acid, has a beneficial therapeutic effect on acne vulgaris." | 6.16 | [Azelaic acid in the treatment of acne]. ( Breathnach, AS; Nazzaro-Porro, M; Passi, S; Picardo, M; Zina, G, 1989) |
| "Evaluate the efficacy and tolerance of the test product containing Myrtus communis extract and azelaic acid compared with a light moisturizing cream (LCM) in adult females in the acne maintenance phase." | 5.69 | The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study. ( Andrade, LSM; Bacquey, A; Bagatin, E; Baradat, S; Lauze, C; Mengeaud, V; Miot, HA; Rocha, MA; Soares, JLM; Thouvenin, MD, 2023) |
| "Topical azelaic acid (AA) is indicated for acne and rosacea, but there is some evidence for its use for other dermatological conditions." | 5.41 | A systematic review to evaluate the efficacy of azelaic acid in the management of acne, rosacea, melasma and skin aging. ( Campbell, J; Daly, ML; King, S; Maybury, C; Moncrieff, G; Rowe, R, 2023) |
| " This study aims to explore the differences in the effectiveness of azelaic and pyruvic acid peels in the treatment of acne vulgaris." | 5.34 | A comparison of the effectiveness of azelaic and pyruvic acid peels in the treatment of female adult acne: a randomized controlled trial. ( Chilicka, K; Dzieńdziora-Urbińska, I; Rogowska, AM; Szyguła, R; Taradaj, J, 2020) |
| "Azelaic acid is a competitive inhibitor of mitochondrial oxidoreductases and of 5 alpha-reductase, inhibiting the conversion of testosterone to 5-dehydrotestosterone." | 5.28 | [Mechanism of azelaic acid action in acne]. ( De Luca, C; Nazzaro-Porro, M; Passi, S; Picardo, M, 1989) |
| " Azelaic acid cream has been previously approved for acne vulgaris, thus azelaic acid foam may be a viable treatment option for truncal acne." | 5.24 | The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Truncal Acne Vulgaris. ( Del Rosso, JQ; Hoffman, LK; Kircik, LH, 2017) |
| "Treatment with azelaic acid 20 % cream significantly improves acne severity and disease-related QoL in adult women." | 5.22 | Azelaic acid 20 % cream: effects on quality of life and disease severity in adult female acne patients. ( Auer-Grumbach, P; Berghammer, G; Kainz, JT; Lackner, V; Perl-Convalexius, S; Popa, R; Wolfesberger, B, 2016) |
| "0001) number of patients demonstrated improvement over their previous acne treatment regimens after both 4 and 8 weeks of NicAzel (nicotinamide, azelaic acid, zinc, pyridoxine, copper, folic acid; Elorac Inc, Vernon Hills, IL) use." | 5.16 | Inflammatory acne management with a novel prescription dietary supplement. ( Akhavan, A; Day, D; Falcon, R; Iannotta, P; Janiga, A; Kallal, JE; Olansky, A; Shalita, AR; Singri, P, 2012) |
| "This study evaluated the efficacy and tolerability of treating mild-to-moderate facial acne using a new, hand-held, light-emitting diode blue light device in conjunction with a foam cleanser containing 5% glycolic acid and 2% salicylic acid plus a skin rebuilding serum containing 1." | 5.15 | Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. ( Dhawan, S; Wheeland, RG, 2011) |
| "To evaluate the sebostatic effect of three anti-acneic ingredients (azelaic acid, adapalene and benzoyl peroxide) conveyed in cream and to determine whether there is a correlation with the therapeutic results." | 5.12 | Relationship between sebostatic activity, tolerability and efficacy of three topical drugs to treat mild to moderate acne. ( Bragadin, G; Patrone, P; Pillon, B; Stinco, G; Trotter, D, 2007) |
| "Azelaic acid gel is an effective topical monotherapy for mild-to-moderate acne vulgaris; its new gel form is an enrichment of acne therapy." | 5.11 | [Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies]. ( Gollnick, HP; Graupe, K; Zaumseil, RP, 2004) |
| "In a series of investigations using 20% azelaic acid cream as a therapy for acne, it was found that the treatment, compared with its placebo, significantly reduced inflamed lesions after 1 month and non-inflamed lesions after 2 months." | 5.06 | Clinical and laboratory studies on treatment with 20% azelaic acid cream for acne. ( Cunliffe, WJ; Holland, KT, 1989) |
| "The effects of azelaic acid (AZA) on the epidermis of 47 individuals (12 with normal skin, 15 with seborrheic skin and 20 suffering from acne) and on in vitro cultured keratinocytes are reported." | 5.06 | Effects of azelaic acid on sebaceous gland, sebum excretion rate and keratinization pattern in human skin. An in vivo and in vitro study. ( Detmar, M; Gassmüller, J; Gollnick, H; Mayer-da-Silva, A; Müller, R; Orfanos, CE; Parry, A, 1989) |
| "20% azelaic acid cream was compared clinically with it vehicle in a 3-month double-blind study of 92 patients with moderate inflammatory acne." | 5.06 | Clinical studies of 20% azelaic acid cream in the treatment of acne vulgaris. Comparison with vehicle and topical tretinoin. ( Graupe, K; Katsambas, A; Stratigos, J, 1989) |
| "Topical azelaic acid and oral tetracycline were compared in a 6-month double-blind study for treatment of acne vulgaris in 45 male subjects with clinical acne." | 5.06 | Topical azelaic acid and the treatment of acne: a clinical and laboratory comparison with oral tetracycline. ( Bladon, PT; Burke, BM; Cunliffe, WJ; Forster, RA; Holland, KT; King, K, 1986) |
| "Preliminary clinical studies (2) proved the effectiveness of topical azelaic acid (AZA) in the treatment of acne vulgaris." | 5.06 | Long-term treatment of acne with 20% azelaic acid cream. ( Caputo, R; Cavicchini, S, 1989) |
| "In a series of investigation using 20% azelaic acid as a therapy for acne, it was found that the treatment, compared with most common therapies (benzoylperoxide, oral tetracycline) significantly reduced inflamed lesions in papulo-pustular acne." | 5.06 | [National and international experiences with azelaic acid cream in the treatment of papulo-pustular acne]. ( Caputo, R; Cavicchini, S, 1989) |
| "20% azelaic acid cream was compared clinically with its vehicle in a 3-month double-blind study of 92 patients with moderate inflammatory acne." | 5.06 | [National and international clinical experiences with azelaic acid cream in the treatment of comedo acne]. ( Giannotti, B, 1989) |
| " In terms of treatment response (measured using participants' global self-assessment of acne improvement, PGA), azelaic acid was probably less effective than benzoyl peroxide (RR = 0." | 5.05 | Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. ( Liu, G; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020) |
| "To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha-hydroxy acid, and sulphur) for acne." | 5.05 | Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020) |
| " Retinoids and azelaic acid have been widely used to treat acne." | 4.89 | Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color. ( Doig, S; Keri, J; Woolery-Lloyd, HC, 2013) |
| "Benzoyl peroxide was introduced as a basic treatment already in acne therapy 1934." | 4.86 | [Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy]. ( Degitz, K; Fluhr, JW, 2010) |
| "Benzoyl peroxide (BPO) was introduced in the treatment of acne in 1934." | 4.83 | [Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid]. ( Fluhr, JW; Worret, WI, 2006) |
| "Azelaic acid cream (20 percent) is a new topical treatment for acne with an additional therapeutic potential in rosacea and hyperpigmentation disorders." | 4.79 | Efficacy and safety of topical azelaic acid (20 percent cream): an overview of results from European clinical trials and experimental reports. ( Cunliffe, WJ; Gollnick, HP; Graupe, K; Zaumseil, RP, 1996) |
| "Azelaic acid is another option for the topical treatment of mild to moderate inflammatory acne vulgaris." | 4.79 | Azelaic acid therapy for acne. ( Mackrides, PS; Shaughnessy, AF, 1996) |
| "Azelaic acid is a naturally occurring saturated dicarboxylic acid which, on topical application (usually as a 20% cream), has been shown to be effective in the treatment of comedonal acne and inflammatory (papulopustular, nodular and nodulocystic) acne, as well as various cutaneous hyperpigmentary disorders characterised by hyperactive/abnormal melanocyte function, including melasma and, possibly, lentigo maligna." | 4.78 | Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders. ( Fitton, A; Goa, KL, 1991) |
| "The current work was aimed at the development of a topical drug delivery system for azelaic acid (AzA) for acne treatment." | 4.31 | The Formulation and Evaluation of Deep Eutectic Vehicles for the Topical Delivery of Azelaic Acid for Acne Treatment. ( Al-Adham, I; Al-Akayleh, F; Al-Ani, I; Al-Remawi, M; Ali, HHM; Khanfar, M; Luhaibi, DK; Nasereddin, J; Qinna, NA; Shalan, N, 2023) |
| "In this study, hydrogels containing azelaic acid were developed using chitosan or HPMC (1-7%) for local treatment of acne vulgaris." | 4.12 | Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: formulation, characterization, ( Arpa, MD; Erim, ÜC; Hoş, A; Seçen, İM; Üstündağ Okur, N, 2022) |
| "Azelaic acid (AzA) is a USFDA bioactive prescribed against acne vulgaris." | 4.12 | Hydrogel composite containing azelaic acid and tea tree essential oil as a therapeutic strategy for Propionibacterium and testosterone-induced acne. ( Aljabali, AAA; Bakshi, HA; Bisht, A; Chakraborty, A; Chellappan, DK; Dev, K; Dhiman, T; Dua, K; Gupta, G; Hemrajani, C; Negi, P; Nidhi, P; Rathore, C; Rolta, R; Sourirajan, A; Tambuwala, MM; Upadhyay, N, 2022) |
| "To overcome the poor solubility, skin irritation, and low permeability of azelaic acid (AZA) existed on the marketed formulations, a co-drug principle via matrine (MAT) was adopted to prepare anti-acne dissolving microneedles (DMNs)." | 4.02 | Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine. ( Gao, Y; Xing, M; Yang, G; Zhang, S, 2021) |
| " Chemical peeling is a well-known option in the treatment of acne vulgaris, but little is known about azelaic acid (AZA) peels." | 4.02 | Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne. ( Budzisz, E; Erkiert-Polguj, A; Szymańska, A, 2021) |
| "To examine the efficacy and safety of azelaic acid 15% foam in the treatment of moderate-to-severe facial acne Methods: Twenty subjects with moderate-to-severe facial acne vulgaris were enrolled in this two-center, open-label pilot study." | 3.88 | The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris. ( Chen, T; Harper, JC; Hashim, PW; Kircik, LH, 2018) |
| "Azelaic acid is a dicarboxylic acid compound used in treatment of acne vulgaris." | 3.85 | A prodrug approach to enhance azelaic acid percutaneous availability. ( Al-Bakri, AG; Al-Marabeh, S; Alzweiri, M; Khalil, E; Khanfar, M, 2017) |
| "The aim of this study was to evaluate a formulation made of poly(lactide-co-glycolide) (PLGA) nanoparticles containing azelaic acid for potential acne treatment." | 3.80 | Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment. ( Fernandes, AS; Martinho, N; Reis, CP; Roberto, A; Rosado, C, 2014) |
| "Azelaic acid (AzA) is used in the treatment of acne." | 3.79 | Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles. ( Ascensão, L; Baptista, M; Candeias, S; Gomes, A; Martinho, N; Pinto, P; Reis, CP; Rijo, P, 2013) |
| "Azelaic acid (AzA), a nine-carbon dicarboxylic acid, is an agent for the topical treatment of acne." | 3.76 | Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARgamma activation. ( Aspite, N; Camera, E; Cardinali, G; Graupe, K; Izzo, E; Mastrofrancesco, A; Ottaviani, M; Picardo, M; Zouboulis, CC, 2010) |
| "Thirty patients of either sex (23 M, 7 F) ranging in age between 16 and 36 years, affected of acne vulgaris, were given 20% azelaic acid cream over a period of 6 months." | 3.67 | [Topical therapeutic action of azelaic acid in polymorphous acne]. ( Florio, T; Petruzzellis, V; Troccoli, T, 1989) |
| "Patients treated with azelaic acid (15%) cream for chloasma reported simultaneous improvement of acne lesions within the treated areas." | 3.66 | Beneficial effect of 15% azelaic acid cream on acne vulgaris. ( Breathnach, A; Clayton, R; Nazzaro-Porro, M; Passi, S; Picardo, M; Zina, G, 1983) |
| "Acne and rosacea are common inflammatory skin conditions present in numerous racial and ethnic groups." | 2.82 | Acne and rosacea in skin of colour. ( Maruthappu, T; Taylor, M, 2022) |
| "Azelaic acid has numerous pharmacological uses in dermatology." | 2.82 | The versatility of azelaic acid in dermatology. ( Al-Niaimi, F; Ali, FR; Searle, T, 2022) |
| "AzA15% gel is a safe and effective treatment and maintenance treatment of female adult acne with non-inferior efficacy to AD 0." | 2.80 | A randomized investigator-blind parallel-group study to assess efficacy and safety of azelaic acid 15% gel vs. adapalene 0.1% gel in the treatment and maintenance treatment of female adult acne. ( Gollnick, H; Kropf, S; Lux, A; Papakonstantinou, E; Thielitz, A; Wiede, A, 2015) |
| "Recognition that acne is an inflammatory condition, not an infectious one, has led to a call for reduction in antibiotic use." | 2.61 | An Overview of Acne Therapy, Part 1: Topical therapy, Oral Antibiotics, Laser and Light Therapy, and Dietary Interventions. ( Baldwin, HE; Marson, JW, 2019) |
| "Azelaic acid is a complex molecule with many diverse activities." | 2.52 | Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application. ( Rosen, T; Schulte, BC; Wu, W, 2015) |
| "Acne is a common skin disorder that can be problematic for adults as well as for adolescents." | 2.50 | Azelaic acid: Properties and mode of action. ( Hegel, JK; Sieber, MA, 2014) |
| "Acne vulgaris is a very common inflammatory skin disease originating from the pilosebaceous unit." | 2.47 | Acne vulgaris in children and adolescents. ( Mempel, M; Schnopp, C, 2011) |
| "Azelaic acid (AzA) is a naturally occurring dicarboxylic acid that has a long and complex history in the treatment of skin disorders." | 2.43 | The evolution of azelaic acid. ( Fleischer, AB, 2006) |
| "The management of acne is a gratifying experience." | 2.43 | Managing acne vulgaris effectively. ( Goodman, G, 2006) |
| "Acne is a common problem in adolescents and young adults." | 2.41 | Topical therapy for acne. ( Russell, JJ, 2000) |
| "Though acne is not generally cured, treatment can reduce the severity and frequency of outbreaks, lessen discomfort from inflamed lesions, improve appearance, and prevent or minimize scarring, thereby averting or ameliorating potentially serious adverse psychosocial effects." | 2.40 | Acne vulgaris: a treatment update. ( Quan, MA; Strick, R; Usatine, RP, 1998) |
| "Acne is one of the most common diseases in dermatology." | 2.40 | Advances and perspectives in acne therapy. ( Jansen, T; Plewig, G, 1997) |
| "Azelaic acid also has significant antimicrobial activity relevant to its efficacy in acne vulgaris." | 2.39 | Rationale for the development of new topical treatments for acne vulgaris. ( Gibson, JR, 1996) |
| " Patients were treated with a supplement based on biotin and 3 strains of lactic ferments, combined with a topical gel product (azelaic-acid, hydroxypinacolone retinoate, and α-hydroxy acids)." | 1.72 | Probiotic supplement combined with topical therapy in the treatment of mild to moderate acne: results from an Italian single centre interventional study. ( Annunziata, MC; Cacciapuoti, S; Fabbrocini, G; Marasca, C; Ruggiero, A, 2022) |
| "Acne vulgaris is a pervasive inflammatory disorder of the skin, with multiple etiologies and treatment options." | 1.40 | Acne vulgaris in the context of complex medical co-morbities: the management of severe acne vulgaris in a female with retinitis pigmentosa - utilizing pulse dye laser in conjunction with medical therapy. ( Keck, L; Shariff, A; Zlotoff, B, 2014) |
| "Acne should be treated during pregnancy to prevent worsening, scarring, secondary infection or psychological impairment of the mother." | 1.39 | [Acne therapy in pregnancy]. ( Bayerl, C, 2013) |
| "Azelaic acid has strong antibacterial potency without inducing bacterial resistance similar to benzoyl peroxide." | 1.30 | Topical drug treatment in acne. ( Gollnick, H; Schramm, M, 1998) |
| "Azelaic acid is a competitive inhibitor of mitochondrial oxidoreductases and of 5 alpha-reductase, inhibiting the conversion of testosterone to 5-dehydrotestosterone." | 1.28 | [Mechanism of azelaic acid action in acne]. ( De Luca, C; Nazzaro-Porro, M; Passi, S; Picardo, M, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (21.00) | 18.7374 |
| 1990's | 18 (18.00) | 18.2507 |
| 2000's | 17 (17.00) | 29.6817 |
| 2010's | 29 (29.00) | 24.3611 |
| 2020's | 15 (15.00) | 2.80 |
| Authors | Studies |
|---|---|
| Maruthappu, T | 1 |
| Taylor, M | 1 |
| Szymańska, A | 2 |
| Budzisz, E | 2 |
| Erkiert-Polguj, A | 2 |
| Bisht, A | 2 |
| Hemrajani, C | 2 |
| Rathore, C | 2 |
| Dhiman, T | 1 |
| Rolta, R | 2 |
| Upadhyay, N | 2 |
| Nidhi, P | 2 |
| Gupta, G | 2 |
| Dua, K | 2 |
| Chellappan, DK | 2 |
| Dev, K | 2 |
| Sourirajan, A | 2 |
| Chakraborty, A | 1 |
| Aljabali, AAA | 1 |
| Bakshi, HA | 2 |
| Negi, P | 2 |
| Tambuwala, MM | 2 |
| Aljabali, AA | 1 |
| Arpa, MD | 1 |
| Seçen, İM | 1 |
| Erim, ÜC | 1 |
| Hoş, A | 1 |
| Üstündağ Okur, N | 1 |
| Marasca, C | 1 |
| Ruggiero, A | 1 |
| Cacciapuoti, S | 1 |
| Fabbrocini, G | 1 |
| Annunziata, MC | 1 |
| Bagatin, E | 2 |
| Thouvenin, MD | 1 |
| Bacquey, A | 1 |
| Baradat, S | 1 |
| Lauze, C | 1 |
| Mengeaud, V | 1 |
| Soares, JLM | 1 |
| Andrade, LSM | 1 |
| Miot, HA | 1 |
| Rocha, MA | 1 |
| King, S | 1 |
| Campbell, J | 1 |
| Rowe, R | 1 |
| Daly, ML | 1 |
| Moncrieff, G | 1 |
| Maybury, C | 1 |
| Luhaibi, DK | 1 |
| Ali, HHM | 1 |
| Al-Ani, I | 1 |
| Shalan, N | 1 |
| Al-Akayleh, F | 1 |
| Al-Remawi, M | 1 |
| Nasereddin, J | 1 |
| Qinna, NA | 1 |
| Al-Adham, I | 1 |
| Khanfar, M | 2 |
| Liu, H | 2 |
| Yu, H | 2 |
| Xia, J | 2 |
| Liu, L | 2 |
| Liu, GJ | 1 |
| Sang, H | 2 |
| Peinemann, F | 2 |
| Chilicka, K | 1 |
| Rogowska, AM | 1 |
| Szyguła, R | 1 |
| Dzieńdziora-Urbińska, I | 1 |
| Taradaj, J | 1 |
| Searle, T | 1 |
| Ali, FR | 1 |
| Al-Niaimi, F | 1 |
| Liu, G | 1 |
| Xing, M | 1 |
| Yang, G | 1 |
| Zhang, S | 1 |
| Gao, Y | 1 |
| Hoffman, LK | 1 |
| Del Rosso, JQ | 1 |
| Kircik, LH | 3 |
| Melnik, BC | 3 |
| Hashim, PW | 1 |
| Chen, T | 1 |
| Harper, JC | 1 |
| Marson, JW | 1 |
| Baldwin, HE | 1 |
| Bayerl, C | 1 |
| Reis, CP | 2 |
| Martinho, N | 2 |
| Rosado, C | 1 |
| Fernandes, AS | 1 |
| Roberto, A | 1 |
| Woolery-Lloyd, HC | 1 |
| Keri, J | 1 |
| Doig, S | 1 |
| Gomes, A | 1 |
| Rijo, P | 1 |
| Candeias, S | 1 |
| Pinto, P | 1 |
| Baptista, M | 1 |
| Ascensão, L | 1 |
| Schmitz, G | 2 |
| Sieber, MA | 1 |
| Hegel, JK | 1 |
| Vargas-Diez, E | 1 |
| Hofmann, MA | 1 |
| Bravo, B | 1 |
| Malgazhdarova, G | 1 |
| Katkhanova, OA | 1 |
| Yutskovskaya, Y | 1 |
| Shariff, A | 1 |
| Keck, L | 1 |
| Zlotoff, B | 1 |
| Thielitz, A | 1 |
| Lux, A | 1 |
| Wiede, A | 1 |
| Kropf, S | 1 |
| Papakonstantinou, E | 1 |
| Gollnick, H | 5 |
| Schulte, BC | 1 |
| Wu, W | 1 |
| Rosen, T | 1 |
| Albuquerque, RG | 1 |
| da Rocha, MA | 1 |
| Hirotsu, C | 1 |
| Hachul, H | 1 |
| Tufik, S | 1 |
| Andersen, ML | 1 |
| Schaller, M | 1 |
| Sebastian, M | 1 |
| Ress, C | 1 |
| Seidel, D | 1 |
| Hennig, M | 1 |
| Al-Marabeh, S | 1 |
| Khalil, E | 1 |
| Al-Bakri, AG | 1 |
| Alzweiri, M | 1 |
| Samycia, M | 1 |
| Lam, JM | 1 |
| Kainz, JT | 1 |
| Berghammer, G | 1 |
| Auer-Grumbach, P | 1 |
| Lackner, V | 1 |
| Perl-Convalexius, S | 1 |
| Popa, R | 1 |
| Wolfesberger, B | 1 |
| Zouboulis, CC | 2 |
| Choi, YS | 1 |
| Suh, HS | 1 |
| Yoon, MY | 1 |
| Min, SU | 1 |
| Kim, JS | 1 |
| Jung, JY | 1 |
| Lee, DH | 1 |
| Suh, DH | 1 |
| Pazoki-Toroudi, H | 2 |
| Nassiri-Kashani, M | 2 |
| Tabatabaie, H | 1 |
| Ajami, M | 2 |
| Habibey, R | 1 |
| Shizarpour, M | 1 |
| Babakoohi, S | 1 |
| Rahshenas, M | 1 |
| Firooz, A | 2 |
| Fluhr, JW | 2 |
| Degitz, K | 1 |
| Mastrofrancesco, A | 1 |
| Ottaviani, M | 1 |
| Aspite, N | 1 |
| Cardinali, G | 1 |
| Izzo, E | 1 |
| Graupe, K | 7 |
| Camera, E | 1 |
| Picardo, M | 4 |
| Merkviladze, N | 1 |
| Gaidamashvili, T | 1 |
| Tushurashvili, P | 1 |
| Ekaladze, E | 1 |
| Jojua, N | 1 |
| Nilforoushzadeh, MA | 1 |
| Jaffary, F | 1 |
| Aboutaleb, N | 1 |
| Wheeland, RG | 1 |
| Dhawan, S | 1 |
| Schnopp, C | 1 |
| Mempel, M | 1 |
| Shalita, AR | 1 |
| Falcon, R | 1 |
| Olansky, A | 1 |
| Iannotta, P | 1 |
| Akhavan, A | 1 |
| Day, D | 1 |
| Janiga, A | 1 |
| Singri, P | 1 |
| Kallal, JE | 1 |
| Liao, DC | 1 |
| Purdy, S | 2 |
| Callender, VD | 1 |
| Gollnick, HP | 2 |
| Zaumseil, RP | 2 |
| Fleischer, AB | 1 |
| Worret, WI | 1 |
| Goodman, G | 1 |
| Stinco, G | 1 |
| Bragadin, G | 1 |
| Trotter, D | 1 |
| Pillon, B | 1 |
| Patrone, P | 1 |
| Alevizos, A | 1 |
| Mariolis, A | 1 |
| Larios, G | 1 |
| Thiboutot, D | 1 |
| Nazzaro-Porro, M | 5 |
| Passi, S | 4 |
| Breathnach, A | 1 |
| Clayton, R | 1 |
| Zina, G | 3 |
| Marsden, JR | 1 |
| Shuster, S | 1 |
| Breathnach, AS | 2 |
| Nguyen, QH | 1 |
| Bui, TP | 1 |
| Bojar, RA | 2 |
| Cutcliffe, AG | 1 |
| Cunliffe, WJ | 4 |
| Holland, KT | 4 |
| Gibson, JR | 2 |
| Lowe, NJ | 1 |
| Oh, CW | 1 |
| Myung, KB | 1 |
| Mackrides, PS | 1 |
| Shaughnessy, AF | 1 |
| Jansen, T | 1 |
| Plewig, G | 1 |
| Usatine, RP | 2 |
| Quan, MA | 1 |
| Strick, R | 1 |
| Schramm, M | 2 |
| Russell, JJ | 1 |
| Webster, G | 1 |
| Koczorek, M | 1 |
| Shemer, A | 1 |
| Weiss, G | 1 |
| Amichai, B | 1 |
| Kaplan, B | 1 |
| Trau, H | 1 |
| Fitton, A | 1 |
| Goa, KL | 1 |
| Angius, AG | 1 |
| Barbareschi, M | 1 |
| Cattaneo, M | 1 |
| Monti, M | 1 |
| Caputo, R | 3 |
| Mayer-da-Silva, A | 1 |
| Detmar, M | 1 |
| Gassmüller, J | 1 |
| Parry, A | 1 |
| Müller, R | 1 |
| Orfanos, CE | 2 |
| Töpert, M | 1 |
| Rach, P | 1 |
| Siegmund, F | 1 |
| Katsambas, A | 1 |
| Stratigos, J | 1 |
| Cavicchini, S | 2 |
| Hjorth, N | 1 |
| De Luca, C | 1 |
| Giannotti, B | 1 |
| Colonna, SM | 1 |
| Troccoli, T | 1 |
| Florio, T | 1 |
| Petruzzellis, V | 1 |
| Gassmueller, H | 1 |
| Bladon, PT | 1 |
| Burke, BM | 1 |
| Forster, RA | 1 |
| King, K | 1 |
| Leeming, JP | 1 |
| Auld, J | 1 |
37 reviews available for azelaic acid and Acne
| Article | Year |
|---|---|
Acne and rosacea in skin of colour.
Topics: Acne Vulgaris; Adapalene; Diagnosis, Differential; Dicarboxylic Acids; Humans; Racial Groups; Rosace | 2022 |
A systematic review to evaluate the efficacy of azelaic acid in the management of acne, rosacea, melasma and skin aging.
Topics: Acne Vulgaris; Dermatologic Agents; Erythema; Humans; Melanosis; Rosacea; Skin Aging; Treatment Outc | 2023 |
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Bias; Child; C | 2020 |
The versatility of azelaic acid in dermatology.
Topics: Acne Vulgaris; Dermatologic Agents; Dermatology; Dicarboxylic Acids; Humans; Male; Rosacea | 2022 |
Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review.
Topics: Acne Vulgaris; Administration, Cutaneous; Dermatologic Agents; Dicarboxylic Acids; Fruit; Glycolates | 2020 |
p53: key conductor of all anti-acne therapies.
Topics: Acne Vulgaris; Dicarboxylic Acids; Humans; Isotretinoin; Models, Biological; Photochemotherapy; Tetr | 2017 |
An Overview of Acne Therapy, Part 1: Topical therapy, Oral Antibiotics, Laser and Light Therapy, and Dietary Interventions.
Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; Combined Moda | 2019 |
Retinoids and azelaic acid to treat acne and hyperpigmentation in skin of color.
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Humans; Hyperpigmentation; Retinoids; Skin P | 2013 |
Azelaic acid: Properties and mode of action.
Topics: Acne Vulgaris; Anti-Bacterial Agents; Anti-Inflammatory Agents; Dermatologic Agents; Dicarboxylic Ac | 2014 |
Azelaic Acid: Evidence-based Update on Mechanism of Action and Clinical Application.
Topics: Acne Vulgaris; Alopecia Areata; Dermatitis, Perioral; Dermatologic Agents; Dicarboxylic Acids; Facia | 2015 |
Anti-acne agents attenuate FGFR2 signal transduction in acne.
Topics: Acne Vulgaris; alpha-MSH; Androgen Antagonists; Benzoyl Peroxide; Dicarboxylic Acids; Erythromycin; | 2009 |
[Antibiotics, azelaic acid and benzoyl peroxide in topical acne therapy].
Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermat | 2010 |
Acne vulgaris in children and adolescents.
Topics: Acne Vulgaris; Administration, Cutaneous; Adolescent; Anti-Bacterial Agents; Benzoyl Peroxide; Child | 2011 |
Management of acne.
Topics: Acne Vulgaris; Adapalene; Administration, Oral; Administration, Topical; Algorithms; Anti-Bacterial | 2003 |
Acne vulgaris.
Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; | 2005 |
Considerations for treating acne in ethnic skin.
Topics: Acne Keloid; Acne Vulgaris; Black People; Cosmetics; Dicarboxylic Acids; Drug Therapy, Combination; | 2005 |
The evolution of azelaic acid.
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Humans; Hyperpigmentation; Rosacea; Skin Dis | 2006 |
[Acne therapy with topical benzoyl peroxide, antibiotics and azelaic acid].
Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents | 2006 |
Managing acne vulgaris effectively.
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Adolescent; Adult; Androgens; Anti-Bac | 2006 |
Acne vulgaris.
Topics: Acne Vulgaris; Adapalene; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Dermatologic Agents; | 2006 |
Versatility of azelaic acid 15% gel in treatment of inflammatory acne vulgaris.
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Dose-Response Relationship, Drug; Gels; Huma | 2008 |
Azelaic acid.
Topics: Acne Vulgaris; Antineoplastic Agents; Dicarboxylic Acids; Humans; Melanoma; Nevus, Pigmented; Oxidat | 1984 |
Azelaic acid: pharmacokinetic and pharmacodynamic properties and its therapeutic role in hyperpigmentary disorders and acne.
Topics: Acne Vulgaris; Animals; Anti-Infective Agents; Antineoplastic Agents; Cell Division; Cell Survival; | 1995 |
Azelaic acid--a new topical treatment for acne.
Topics: Acne Vulgaris; Administration, Topical; Dermatologic Agents; Dicarboxylic Acids; Humans; Randomized | 1993 |
Rationale for the development of new topical treatments for acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Carboxylic Acids; Dermatologic Agents; Dicarboxylic Acids; H | 1996 |
Efficacy and safety of topical azelaic acid (20 percent cream): an overview of results from European clinical trials and experimental reports.
Topics: Acne Vulgaris; Administration, Topical; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic | 1996 |
Azelaic acid therapy for acne.
Topics: Acne Vulgaris; Administration, Cutaneous; Dermatologic Agents; Dicarboxylic Acids; Humans | 1996 |
Advances and perspectives in acne therapy.
Topics: Acne Vulgaris; Administration, Topical; Androgen Antagonists; Anti-Infective Agents, Local; Benzoyl | 1997 |
Azelaic acid 20% cream (AZELEX) and the medical management of acne vulgaris.
Topics: Acne Vulgaris; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic Acids; Humans; Ointments | 1997 |
Acne vulgaris: a treatment update.
Topics: Acne Vulgaris; Adapalene; Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; An | 1998 |
Topical therapy in acne.
Topics: Acne Vulgaris; Administration, Cutaneous; Androgen Antagonists; Anti-Bacterial Agents; Bacteria; Ben | 1998 |
Topical therapy for acne.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Anti-Infective Age | 2000 |
Combination azelaic acid therapy for acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic | 2000 |
Azelaic acid. A review of its pharmacological properties and therapeutic efficacy in acne and hyperpigmentary skin disorders.
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Humans; Pigmentation Disorders | 1991 |
[Azelaic acid in the treatment of acne].
Topics: Acne Vulgaris; Adolescent; Animals; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic Acid | 1989 |
Topical therapy of acne.
Topics: Acne Vulgaris; Administration, Topical; Benzoyl Peroxide; Clindamycin; Dicarboxylic Acids; Erythromy | 1986 |
Azelaic acid.
Topics: Acne Vulgaris; Antineoplastic Agents; Dicarboxylic Acids; Humans; Skin Diseases; Skin Neoplasms | 1987 |
24 trials available for azelaic acid and Acne
| Article | Year |
|---|---|
The usefulness of a dermocosmetic containing Myrtus communis extract and azelaic acid for maintenance phase of adult female acne: Results from a randomized exploratory investigator-blinded comparative study.
Topics: Acne Vulgaris; Adult; Dermatologic Agents; Female; Humans; Immunoglobulin A; Myrtus; Severity of Ill | 2023 |
A comparison of the effectiveness of azelaic and pyruvic acid peels in the treatment of female adult acne: a randomized controlled trial.
Topics: Acne Vulgaris; Adult; Analysis of Variance; Dicarboxylic Acids; Female; Humans; Porosity; Pyruvic Ac | 2020 |
The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Truncal Acne Vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Child; Dermatologic Agents; Dicarboxylic | 2017 |
A randomized investigator-blind parallel-group study to assess efficacy and safety of azelaic acid 15% gel vs. adapalene 0.1% gel in the treatment and maintenance treatment of female adult acne.
Topics: Acne Vulgaris; Adapalene; Adult; Dermatologic Agents; Dicarboxylic Acids; Female; Gels; Humans; Main | 2015 |
A randomized comparative trial of a combined oral contraceptive and azelaic acid to assess their effect on sleep quality in adult female acne patients.
Topics: Acne Vulgaris; Adrenocorticotropic Hormone; Adult; Central Nervous System; Contraceptives, Oral, Com | 2015 |
A multicentre, randomized, single-blind, parallel-group study comparing the efficacy and tolerability of benzoyl peroxide 3%/clindamycin 1% with azelaic acid 20% in the topical treatment of mild-to-moderate acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Benzoyl Peroxide; Child; Clindamycin; Dic | 2016 |
Azelaic acid 20 % cream: effects on quality of life and disease severity in adult female acne patients.
Topics: Acne Vulgaris; Administration, Cutaneous; Adolescent; Adult; Age Distribution; Austria; Dermatologic | 2016 |
A study of the efficacy of cleansers for acne vulgaris.
Topics: Acne Vulgaris; Administration, Cutaneous; Adult; Detergents; Dicarboxylic Acids; Dose-Response Relat | 2010 |
Combination of azelaic acid 5% and erythromycin 2% in the treatment of acne vulgaris.
Topics: Acne Vulgaris; Administration, Cutaneous; Adolescent; Adult; Analysis of Variance; Anti-Bacterial Ag | 2010 |
Combination of azelaic acid 5% and clindamycin 2% for the treatment of acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Clindamycin; Dermatologic Agents; Dic | 2011 |
Efficacy and safety of azelaic acid (AzA) gel 15% in the treatment of post-inflammatory hyperpigmentation and acne: a 16-week, baseline-controlled study.
Topics: Acne Vulgaris; Administration, Cutaneous; Black People; Dermatologic Agents; Dicarboxylic Acids; Fem | 2011 |
Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system.
Topics: Acne Vulgaris; Adult; Combined Modality Therapy; Dermatologic Agents; Dicarboxylic Acids; Drug Combi | 2011 |
Inflammatory acne management with a novel prescription dietary supplement.
Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Copper; Dicarboxylic Acids; Dietary | 2012 |
[Azelaic acid 15% gel in the treatment of acne vulgaris. Combined results of two double-blind clinical comparative studies].
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; | 2004 |
Relationship between sebostatic activity, tolerability and efficacy of three topical drugs to treat mild to moderate acne.
Topics: Acne Vulgaris; Adapalene; Administration, Topical; Adolescent; Analysis of Variance; Benzoyl Peroxid | 2007 |
Effects of azelaic acid on sebaceous gland, sebum excretion rate and keratinization pattern in human skin. An in vivo and in vitro study.
Topics: Acne Vulgaris; Cell Differentiation; Cell Division; Cells, Cultured; Clinical Trials as Topic; Derma | 1989 |
Clinical and laboratory studies on treatment with 20% azelaic acid cream for acne.
Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Clinical Trials as Topic; Dicarboxyli | 1989 |
Clinical studies of 20% azelaic acid cream in the treatment of acne vulgaris. Comparison with vehicle and topical tretinoin.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Child; Clinical Trials as Topic; Dicarbox | 1989 |
Long-term treatment of acne with 20% azelaic acid cream.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Benzoyl Peroxide; Dicarboxylic Acids; Fem | 1989 |
Azelaic acid for the treatment of acne. A clinical comparison with oral tetracycline.
Topics: Acne Vulgaris; Administration, Topical; Clinical Trials as Topic; Dicarboxylic Acids; Drug Tolerance | 1989 |
[Azelaic acid in the treatment of acne].
Topics: Acne Vulgaris; Adolescent; Animals; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic Acid | 1989 |
[National and international experiences with azelaic acid cream in the treatment of papulo-pustular acne].
Topics: Acne Vulgaris; Administration, Oral; Adolescent; Benzoyl Peroxide; Clinical Trials as Topic; Dermato | 1989 |
[National and international clinical experiences with azelaic acid cream in the treatment of comedo acne].
Topics: Acne Vulgaris; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic Acids; Double-Blind Metho | 1989 |
Topical azelaic acid and the treatment of acne: a clinical and laboratory comparison with oral tetracycline.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Clinical Trials as Topic; Dicarboxylic Ac | 1986 |
40 other studies available for azelaic acid and Acne
| Article | Year |
|---|---|
Long-term effect of azelaic acid peel on sebum production in acne.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Dicarboxylic Acids; Female; Humans; Male; Sebum; Young Adult | 2022 |
Hydrogel composite containing azelaic acid and tea tree essential oil as a therapeutic strategy for Propionibacterium and testosterone-induced acne.
Topics: Acne Vulgaris; Animals; Dicarboxylic Acids; Hydrogels; Propionibacterium; Rats; Rats, Wistar; Tea; T | 2022 |
Azelaic acid and
Topics: Acne Vulgaris; Animals; Anti-Bacterial Agents; Dicarboxylic Acids; Excipients; Hydrogels; Melaleuca; | 2022 |
Azelaic acid loaded chitosan and HPMC based hydrogels for treatment of acne: formulation, characterization,
Topics: Acne Vulgaris; Chitosan; Dicarboxylic Acids; Humans; Hydrogels | 2022 |
Probiotic supplement combined with topical therapy in the treatment of mild to moderate acne: results from an Italian single centre interventional study.
Topics: Acne Vulgaris; Biotin; Dermatologic Agents; Humans; Hydroxy Acids; Probiotics | 2022 |
The Formulation and Evaluation of Deep Eutectic Vehicles for the Topical Delivery of Azelaic Acid for Acne Treatment.
Topics: Acne Vulgaris; Animals; Choline; Dermatologic Agents; Dicarboxylic Acids; Pharmaceutical Preparation | 2023 |
Efficacy of 30% azelaic acid peel in the nonpharmacological treatment of facial acne.
Topics: Acne Vulgaris; Adolescent; Adult; Dicarboxylic Acids; Drug Administration Schedule; Face; Female; Hu | 2021 |
Acid-base combination principles for preparation of anti-acne dissolving microneedles loaded with azelaic acid and matrine.
Topics: Acne Vulgaris; Administration, Cutaneous; Alkaloids; Animals; Dicarboxylic Acids; Matrines; Quinoliz | 2021 |
The Efficacy and Safety of Azelaic Acid 15% Foam in the Treatment of Facial Acne Vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Dermatitis; Dicarboxylic Acids; Drug Comp | 2018 |
[Acne therapy in pregnancy].
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Adrenal Cortex Hormones; Benzoyl Perox | 2013 |
Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment.
Topics: Acne Vulgaris; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dicarboxylic A | 2014 |
Development and evaluation of a novel topical treatment for acne with azelaic acid-loaded nanoparticles.
Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Delayed-Action Preparations; Dicarbox | 2013 |
Are therapeutic effects of antiacne agents mediated by activation of FoxO1 and inhibition of mTORC1?
Topics: Acne Vulgaris; AMP-Activated Protein Kinases; Benzoyl Peroxide; Dermatologic Agents; Dicarboxylic Ac | 2013 |
Azelaic acid in the treatment of acne in adult females: case reports.
Topics: Acne Vulgaris; Adult; Anti-Bacterial Agents; Anti-Inflammatory Agents; Dermatologic Agents; Dicarbox | 2014 |
Acne vulgaris in the context of complex medical co-morbities: the management of severe acne vulgaris in a female with retinitis pigmentosa - utilizing pulse dye laser in conjunction with medical therapy.
Topics: Acne Vulgaris; Administration, Cutaneous; Adult; Androstenes; Anti-Infective Agents, Local; Combined | 2014 |
A prodrug approach to enhance azelaic acid percutaneous availability.
Topics: Acne Vulgaris; Administration, Cutaneous; Dermatologic Agents; Dicarboxylic Acids; Gram-Positive Bac | 2017 |
Infantile acne.
Topics: Acne Vulgaris; Age of Onset; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents; Dicarboxy | 2016 |
Azelaic acid modulates the inflammatory response in normal human keratinocytes through PPARgamma activation.
Topics: Acne Vulgaris; Cells, Cultured; Cytokines; Dermatologic Agents; Dicarboxylic Acids; Drug Evaluation, | 2010 |
The efficacy of topical drugs in treatment of noninflammatory acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Dermatologic Agents; Dicarboxylic Acids; | 2010 |
Acne treatments: consider these options--and issues.
Topics: Acne Vulgaris; Anti-Bacterial Agents; Dermatologic Agents; Dicarboxylic Acids; Humans | 2007 |
Beneficial effect of 15% azelaic acid cream on acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Dicarboxylic Acids; Female; Humans; Male; | 1983 |
The effect of azelaic acid on acne.
Topics: Acne Vulgaris; Adolescent; Adult; Dicarboxylic Acids; Female; Humans; Male; Sebum; Secretory Rate | 1983 |
Follicular concentrations of azelaic acid after a single topical application.
Topics: Acne Vulgaris; Administration, Topical; Adult; Back; Bacterial Infections; Chromatography, High Pres | 1993 |
Azelaic acid-a new topical drug for acne.
Topics: Acne Vulgaris; Administration, Topical; Clinical Trials as Topic; Dermatologic Agents; Dicarboxylic | 1996 |
New approaches in dermatology: a clinical profile of azelaic acid.
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Humans; Hyperpigmentation | 1996 |
An ultrastructural study of the retention hyperkeratosis of experimentally induced comedones in rabbits: the effects of three comedolytics.
Topics: Acne Vulgaris; Animals; Benzoyl Peroxide; Dermatologic Agents; Dicarboxylic Acids; Disease Models, A | 1996 |
Topical drug treatment in acne.
Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents | 1998 |
The science and art of treating acne in adolescence.
Topics: Acne Vulgaris; Adolescent; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents; Dicarboxyli | 2000 |
["Cleansing, topical treatment, oral administration". Controlling acne].
Topics: Acne Vulgaris; Administration, Oral; Administration, Topical; Adolescent; Adult; Combined Modality T | 2001 |
Azelaic acid (20%) cream in the treatment of acne vulgaris.
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Dermatologic Agents; Dicarboxylic Acids; | 2002 |
[Azelaic Acid--a new application in acne therapy. Expert's exchange. Berlin, 18-20 January 1991].
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Humans | 1991 |
[Azelaic acid for keratinization disorders?].
Topics: Acne Vulgaris; Dermatologic Agents; Dicarboxylic Acids; Humans; Keratinocytes; Keratosis | 1991 |
[Evaluation of the anti-comedo effect of azelaic acid using the technique of horny layer biopsy and scanning electron microscopy].
Topics: Acne Vulgaris; Adult; Biopsy; Dermatologic Agents; Dicarboxylic Acids; Epidermis; Female; Humans; Ma | 1990 |
Pharmacology and toxicology of azelaic acid.
Topics: Acne Vulgaris; Animals; Anti-Infective Agents; Dicarboxylic Acids; Disease Models, Animal; Lipids; S | 1989 |
[Azelaic acid: an innovation in the treatment of acne. Introduction and history].
Topics: Acne Vulgaris; Administration, Oral; Adolescent; Dermatologic Agents; Dicarboxylic Acids; Drug Evalu | 1989 |
[Mechanism of azelaic acid action in acne].
Topics: Acne Vulgaris; Cholestenone 5 alpha-Reductase; Dermatologic Agents; Dicarboxylic Acids; Humans; Kera | 1989 |
[Validity of azelaic acid in the therapy of acne. Long-term clinical results].
Topics: Acne Vulgaris; Adolescent; Adult; Dermatologic Agents; Dicarboxylic Acids; Drug Evaluation; Female; | 1989 |
[Topical therapeutic action of azelaic acid in polymorphous acne].
Topics: Acne Vulgaris; Adolescent; Adult; Dermatologic Agents; Dicarboxylic Acids; Drug Evaluation; Female; | 1989 |
Azelaic acid and sebum excretion rate.
Topics: Acne Vulgaris; Dicarboxylic Acids; Humans; Sebum; Secretory Rate | 1985 |
The in vitro antimicrobial effect of azelaic acid.
Topics: Acne Vulgaris; Bacteria; Culture Media; Dicarboxylic Acids; Humans; Malassezia; Microbial Sensitivit | 1986 |