Page last updated: 2024-12-05

1-nonanol

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

1-Nonanol, also known as nonyl alcohol, is a fatty alcohol with the formula CH3(CH2)8OH. It is a colorless liquid with a faint, sweet odor. 1-nonanol is found naturally in various plants and animals, and it is also produced commercially.

It is commonly used as a solvent, fragrance ingredient, and intermediate in the production of other chemicals. 1-nonanol has been investigated for its potential applications in cosmetics, pharmaceuticals, and biofuels. It is a key component in the production of various esters, which are used as plasticizers, lubricants, and flavoring agents. The study of 1-nonanol focuses on its synthesis, properties, and potential applications in various fields.'

nonanol : A fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of nine carbon atoms. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

nonan-1-ol : A nonanol that is nonane substituted by a hydroxy group at position 1. It has been isolated as a component of volatile oils from plants like Hordeum vulgare. [Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

FloraRankFlora DefinitionFamilyFamily Definition
HordeumgenusA plant genus of the family POACEAE. The EDIBLE GRAIN, barley, is widely used as food.[MeSH]PoaceaeA large family of narrow-leaved herbaceous grasses of the order Cyperales, subclass Commelinidae, class Liliopsida (monocotyledons). Food grains (EDIBLE GRAIN) come from members of this family. RHINITIS, ALLERGIC, SEASONAL can be induced by POLLEN of many of the grasses.[MeSH]

Cross-References

ID SourceID
PubMed CID8914
CHEMBL ID24563
CHEBI ID35986
SCHEMBL ID19807
MeSH IDM0063462

Synonyms (77)

Synonym
BIDD:ER0370
pelargonalkohol
n-nonanol
nonylalkohol
CHEBI:35986 ,
AKOS009031412
octyl carbinol
nsc-5521
143-08-8
pelargonic alcohol
wln: q9
n-nonan-1-ol
nonan-1-ol
nonyl alcohol
1-nonanol
alcohol c-9
nsc5521
nonalol
n-nonyl alcohol
nonanol
bdbm22607
c9 alcohol
ai3-03962
nsc 5521
brn 0969213
einecs 205-583-7
fema no. 2789
hsdb 5145
inchi=1/c9h20o/c1-2-3-4-5-6-7-8-9-10/h10h,2-9h2,1h
1-hydroxynonane
nonyl alcohol, >=98%, fcc
DB03143
1-nonanol, 98%
28473-21-4
2E051A08-F94E-40C2-88CA-7030E15C76BF
CHEMBL24563
N0292
LMFA05000092
A808013
NCGC00248194-01
ngk73q6xmc ,
4-01-00-01798 (beilstein handbook reference)
unii-ngk73q6xmc
ec 205-583-7
tox21_300869
dtxsid6022008 ,
dtxcid402008
cas-143-08-8
NCGC00254773-01
einecs 249-048-6
STL283956
FT-0608164
SCHEMBL19807
nonyl alcohol [hsdb]
n-nonyl alcohol [mi]
nonyl alcohol [fhfi]
nonyl alcohol [fcc]
nonanol-(1)
alcohol c9
mfcd00002990
1-nonanol, purum, >=98.0% (gc)
n-nonyl-alcohol
nonyl-alcohol
D70513
J-007741
nonyl alcohol, 8ci
fema 2789
F0001-0508
Q161662
nonanols
BP-31117
BS-42231
CS-W009532
EN300-19921
SY011469
Z104476100
HY-W008816
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Roles (4)

RoleDescription
plant metaboliteAny eukaryotic metabolite produced during a metabolic reaction in plants, the kingdom that include flowering plants, conifers and other gymnosperms.
volatile oil componentAny plant metabolite that is found naturally as a component of a volatile oil.
flavouring agentA food additive that is used to added improve the taste or odour of a food.
antifungal agentAn antimicrobial agent that destroys fungi by suppressing their ability to grow or reproduce.
[role information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Drug Classes (2)

ClassDescription
nonanolA fatty alcohol consisting of a hydroxy function at any position of an unbranched saturated chain of nine carbon atoms.
primary alcoholA primary alcohol is a compound in which a hydroxy group, -OH, is attached to a saturated carbon atom which has either three hydrogen atoms attached to it or only one other carbon atom and two hydrogen atoms attached to it.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Protein Targets (1)

Potency Measurements

ProteinTaxonomyMeasurementAverage (µ)Min (ref.)Avg (ref.)Max (ref.)Bioassay(s)
AR proteinHomo sapiens (human)Potency68.58960.000221.22318,912.5098AID1259243
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Bioassays (12)

Assay IDTitleYearJournalArticle
AID1347082qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: LASV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347083qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lassa (LASV) Arenavirus: Viability assay - alamar blue signal for LASV Primary Screen2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1347086qHTS for Inhibitors of the Functional Ribonucleoprotein Complex (vRNP) of Lymphocytic Choriomeningitis Arenaviruses (LCMV): LCMV Primary Screen - GLuc reporter signal2020Antiviral research, 01, Volume: 173A cell-based, infectious-free, platform to identify inhibitors of lassa virus ribonucleoprotein (vRNP) activity.
AID1101855Antifungal activity against Saccharomyces cerevisiae ATCC 7754 after 48 hr by microdilution method2002Journal of agricultural and food chemistry, Jul-03, Volume: 50, Issue:14
Molecular design of antifungal agents.
AID1133174Antihemolytic potency against hypotonic lysis-induced erythrocytes (unknown origin) assessed as stabilization1978Journal of medicinal chemistry, Dec, Volume: 21, Issue:12
Molar volume relationships and the specific inhibition of a synaptosomal enzyme by psychoactive cannabinoids.
AID1081320Nematicidal activity against Bursaphelenchus xylophilus assessed as mortality at 0.0625 mg/ml measured after 48 hr under microscope2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Structure-activity relationship of aliphatic compounds for nematicidal activity against pine wood nematode (Bursaphelenchus xylophilus).
AID1133173Inhibition of mouse brain synaptosomal Lysophosphatidylcholine acyltransferase using substrate [32P]lysophosphatidylcholine and oleoyl-CoA1978Journal of medicinal chemistry, Dec, Volume: 21, Issue:12
Molar volume relationships and the specific inhibition of a synaptosomal enzyme by psychoactive cannabinoids.
AID332912Antimicrobial activity Propionibacterium acnes ATCC 11827 after 2 days by broth dilution method1994Journal of natural products, Jan, Volume: 57, Issue:1
Naturally occurring antiacne agents.
AID1081323Nematicidal activity against Bursaphelenchus xylophilus at 0.5 mg/ml measured after 48 hr under microscope2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Structure-activity relationship of aliphatic compounds for nematicidal activity against pine wood nematode (Bursaphelenchus xylophilus).
AID1133175Molar volume, Vm of the compound at zero temperature1978Journal of medicinal chemistry, Dec, Volume: 21, Issue:12
Molar volume relationships and the specific inhibition of a synaptosomal enzyme by psychoactive cannabinoids.
AID1081321Nematicidal activity against Bursaphelenchus xylophilus assessed as mortality at 0.125 mg/ml measured after 48 hr under microscope2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Structure-activity relationship of aliphatic compounds for nematicidal activity against pine wood nematode (Bursaphelenchus xylophilus).
AID1081322Nematicidal activity against Bursaphelenchus xylophilus assessed as mortality at 0.25 mg/ml measured after 48 hr under microscope2010Journal of agricultural and food chemistry, Feb-10, Volume: 58, Issue:3
Structure-activity relationship of aliphatic compounds for nematicidal activity against pine wood nematode (Bursaphelenchus xylophilus).
[information is prepared from bioassay data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-19901 (5.26)18.7374
1990's4 (21.05)18.2507
2000's4 (21.05)29.6817
2010's4 (21.05)24.3611
2020's6 (31.58)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 51.50

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be very strong demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index51.50 (24.57)
Research Supply Index3.00 (2.92)
Research Growth Index5.07 (4.65)
Search Engine Demand Index76.57 (26.88)
Search Engine Supply Index2.00 (0.95)

This Compound (51.50)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials0 (0.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (100.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]