Page last updated: 2024-10-18

glycolic acid and Acne

glycolic acid has been researched along with Acne in 53 studies

glycolic acid: RN given refers to parent cpd
glycolic acid : A 2-hydroxy monocarboxylic acid that is acetic acid where the methyl group has been hydroxylated.

Research Excerpts

ExcerptRelevanceReference
"The efficacy and safety of commercial low-concentration glycolic acid products on acne were evaluated by recruiting volunteers accompanying mild to moderate acne of different ages and genders, which is a clinical practice for acne."9.51Efficacy and safety of 5% glycolic acid-based Gel essence in the treatment of mild to moderate acne. ( Chen, L; Du, X; Li, L; Lin, H; Lu, L; Tu, S; Zhang, M; Zhang, T, 2022)
"To compare efficacy and safety of combining microneedling with 35% glycolic acid (GA) peel versus microneedling with 15% trichloroacetic acid (TCA) peel in facial atrophic acne scars."9.51Efficacy of Microneedling With 35% Glycolic Acid Peels Versus Microneedling With 15% Trichloroacetic Acid Peels in Treatment of Atrophic Acne Scars: A Randomized Controlled Trial. ( Dayal, S; Kaur, R; Sahu, P, 2022)
"5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution."9.27Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018)
"Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks."9.24Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars-A randomized controlled trial. ( Chander, R; Mendiratta, V; Rana, S, 2017)
"Glycolic acid (GA) peels are frequently performed as adjuvants to the treatment of facial acne."9.19Clinical evaluation of glycolic acid chemical peeling in patients with acne vulgaris: a randomized, double-blind, placebo-controlled, split-face comparative study. ( Furukawa, F; Kaminaka, C; Matsunaka, H; Uede, M; Yamomoto, Y, 2014)
"The 10% glycolic acid containing oil-in-water emulsion improved mild acne applied as monotherapy in this study significantly, already after 45 days of treatment."9.15A 10% glycolic acid containing oil-in-water emulsion improves mild acne: a randomized double-blind placebo-controlled trial. ( Abels, C; Kaszuba, A; Knie, U; Michalak, I; Werdier, D, 2011)
" This study was designed to compare the therapeutic effects of glycolic acid (GA) peels and amino fruit acid (AFA) peels in patients with acne vulgaris."9.14Glycolic acid peels versus amino fruit acid peels for acne. ( Biçak, MU; Demirtaşoğlu, M; Ilknur, T; Ozkan, S, 2010)
"1% retinaldehyde/6% glycolic acid (RALGA) cream at preventing and treating acne scarring in patients previously treated for moderate acne."9.12Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring. ( Dreno, B; Jancovici, E; Katsambas, A; Khammari, A; Morinet, P; Nocera, T; Pelfini, C; Plantier, D; Ribet, V, 2007)
"Retinaldehyde (RAL), a key metabolite between vitamin A and retinoic acid, acts by modulating differentiation and proliferation of keratinocytes, which is of interest in acne lesions, mainly retentional lesions."9.11Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients. ( Carré, C; Dréno, B; Nocera, T; Ségard, C; Verrière, F; Vienne, MP; Vitse, S, 2005)
"Retinaldehyde and glycolic acid are both efficient in acne."9.11Efficacy and safety of 0.1% retinaldehyde/ 6% glycolic acid (diacneal) for mild to moderate acne vulgaris. A multicentre, double-blind, randomized, vehicle-controlled trial. ( Adhoute, H; Lauze, C; Morinet, P; Poli, F; Ribet, V, 2005)
"Twenty-six patients with facial acne were treated simultaneously with 70% glycolic acid and Jessner's solution biweekly on each side of the face."9.09Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999)
"Glycolic acid peeling is an effective modality for the treatment of atrophic acne scars, but repetitive peels (at least six times) with 70% concentration are necessary to obtain evident improvement."9.09Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. ( Akçali, C; Erbağci, Z, 2000)
"To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha-hydroxy acid, and sulphur) for acne."9.05Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"The effects of topical azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid (alpha-hydroxy acid) for acne are unclear."9.05Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. ( Liu, G; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"We designed a prospective study to assess the efficacy of our serum composed of glycolic and salicylic acid for patients suffering from mild to moderate inflammatory and cystic acne, rosacea, folliculitis, and keratosis pilaris."7.96Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders. ( Haddad, L; Wiegmann, D, 2020)
"Glycolic acid is the smallest alpha hydroxy acid and widely used for skincare applications, including to treat acne vulgaris."7.96pH-Dependent Antibacterial Activity of Glycolic Acid: Implications for Anti-Acne Formulations. ( Cho, NJ; Jackman, JA; Mokrzecka, N; Valle-González, ER; Yoon, BK, 2020)
"The treatment with the three salicylic acid-based products has been related to a significant improvement on acne lesions over 8 weeks of treatment, along with a reduction of personal discomfort related to acne and an improvement on lesions appearance."7.96Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study. ( Bettoli, V; Micali, G; Monfrecola, G; Veraldi, S, 2020)
"To evaluate and compare the efficacy and safety therapy of glycolic acid (GA) peel, microneedling with dermapen and a combination of both procedures in treatment of atrophic acne scars."7.91Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study. ( El-Sayed, W; Esawy, AM; Kandeel, AH; Saadawi, AN, 2019)
"Many clinicians have used glycolic acid (GA) peels for facial acne, scarring, and hyperpigmentation, mainly in lighter skin types."7.75Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. ( Garg, VK; Sarkar, R; Sinha, S, 2009)
"Glycolic acid chemical peels are an effective treatment for all types of acne, inducing rapid improvement and restoration to normal looking skin."7.70Glycolic acid peeling in the treatment of acne. ( Atzori, L; Biggio, P; Brundu, MA; Orru, A, 1999)
"Glycolic acid has considerable therapeutic value for acne with minimal side effects even in Asian skin."7.69The effect of glycolic acid on the treatment of acne in Asian skin. ( Chan, HL; Hu, CT; Huang, CL; Wang, CM, 1997)
"The biggest hurdle in the treatment of acne vulgaris is patient non-compliance that is due in large part to poor tolerability to common acne medications."6.79Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients. ( Bhatia, AC; Jimenez, F, 2014)
"  Acne scars can cause emotional and psychosocial disturbance to the patient."6.76Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin. ( Sharad, J, 2011)
"Acne vulgaris affects 3 out of 4 adolescents and usually vanishes at the end of puberty with either no sequelae or mild to moderate sequelae, such as postinflammatory hyperpigmenation (PIH), which may result in psychological and emotional damages."6.43RALGA (Diacneal), a retinaldehyde and glycolic acid association and postinflammatory hyperpigmentation in acne--a review. ( Katsambas, AD, 2005)
"Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions."5.56Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary resul ( Annunziata, MC; Cinelli, E; Donnarumma, M; Fabbrocini, G; Milani, M; Villani, A, 2020)
"To compare efficacy and safety of combining microneedling with 35% glycolic acid (GA) peel versus microneedling with 15% trichloroacetic acid (TCA) peel in facial atrophic acne scars."5.51Efficacy of Microneedling With 35% Glycolic Acid Peels Versus Microneedling With 15% Trichloroacetic Acid Peels in Treatment of Atrophic Acne Scars: A Randomized Controlled Trial. ( Dayal, S; Kaur, R; Sahu, P, 2022)
"The efficacy and safety of commercial low-concentration glycolic acid products on acne were evaluated by recruiting volunteers accompanying mild to moderate acne of different ages and genders, which is a clinical practice for acne."5.51Efficacy and safety of 5% glycolic acid-based Gel essence in the treatment of mild to moderate acne. ( Chen, L; Du, X; Li, L; Lin, H; Lu, L; Tu, S; Zhang, M; Zhang, T, 2022)
"Acne vulgaris is the most common disease of the adolescence age (70-94%)."5.40Combination therapy with retinaldehyde (0.1%) glycolic acid (6%) and efectiose (0.1%) in mild to moderate acne vulgaris during the period of sun exposure--efficacy and skin tolerability. ( Capizzi, R; De Waure, C; Fossati, B; Frascione, P; Guerriero, C; Masini, F; Ricci, F, 2014)
"A 19-year-old Japanese man had been treated for ulcerative colitis for 2 years."5.37A case of acne fulminans in a patient with ulcerative colitis successfully treated with prednisolone and diaminodiphenylsulfone: a literature review of acne fulminans, rosacea fulminans and neutrophilic dermatoses occurring in the setting of inflammatory ( Danno, K; Fujimoto, N; Tanaka, T; Uenishi, T; Wakabayashi, M, 2011)
"5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution."5.27Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018)
"The aim of this study was to investigate the efficacy of 50% glycolic acid peeling performed at different phases of menstruation on acne."5.24Efficacy of peeling during different periods of the menstrual cycle on acne. ( Bulbul Baskan, E; Saricaoglu, H; Tilki Günay, I, 2017)
"Sixty patients with atrophic acne scars were randomized into group 1 receiving microneedling at 0, 6, and 12 weeks and group 2 receiving microneedling at 0, 6, and 12 weeks along with 70% glycolic acid peel at 3, 9, and 15 weeks."5.24Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars-A randomized controlled trial. ( Chander, R; Mendiratta, V; Rana, S, 2017)
"In this clinical trial, a topical cleansing product containing glycolic acid with pH 4 improved mild acne significantly following twice-daily application for 6 weeks as monotherapy."5.19Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4). ( Abels, C; Knie, U; Lemmnitz, G; Reich, H; Werdier, D, 2014)
" The present study was directed toward safety concerns associated with superficial chemical peeling with glycolic acid (GA) in different concentrations at patients with acne tip I."5.15Side effects assessment in glicolyc acid peelings in patients with acne type I. ( Bubanj, M; Bubanj, S; Jančić, S; Perić, S, 2011)
"This study evaluated the efficacy and tolerability of treating mild-to-moderate facial acne using a new, hand-held, light-emitting diode blue light device in conjunction with a foam cleanser containing 5% glycolic acid and 2% salicylic acid plus a skin rebuilding serum containing 1."5.15Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system. ( Dhawan, S; Wheeland, RG, 2011)
"The 10% glycolic acid containing oil-in-water emulsion improved mild acne applied as monotherapy in this study significantly, already after 45 days of treatment."5.15A 10% glycolic acid containing oil-in-water emulsion improves mild acne: a randomized double-blind placebo-controlled trial. ( Abels, C; Kaszuba, A; Knie, U; Michalak, I; Werdier, D, 2011)
" This study was designed to compare the therapeutic effects of glycolic acid (GA) peels and amino fruit acid (AFA) peels in patients with acne vulgaris."5.14Glycolic acid peels versus amino fruit acid peels for acne. ( Biçak, MU; Demirtaşoğlu, M; Ilknur, T; Ozkan, S, 2010)
"1% retinaldehyde/6% glycolic acid (RALGA) cream at preventing and treating acne scarring in patients previously treated for moderate acne."5.12Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring. ( Dreno, B; Jancovici, E; Katsambas, A; Khammari, A; Morinet, P; Nocera, T; Pelfini, C; Plantier, D; Ribet, V, 2007)
"Retinaldehyde (RAL), a key metabolite between vitamin A and retinoic acid, acts by modulating differentiation and proliferation of keratinocytes, which is of interest in acne lesions, mainly retentional lesions."5.11Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients. ( Carré, C; Dréno, B; Nocera, T; Ségard, C; Verrière, F; Vienne, MP; Vitse, S, 2005)
"Twenty-six patients with facial acne were treated simultaneously with 70% glycolic acid and Jessner's solution biweekly on each side of the face."5.09Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999)
"Glycolic acid peeling is an effective modality for the treatment of atrophic acne scars, but repetitive peels (at least six times) with 70% concentration are necessary to obtain evident improvement."5.09Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars. ( Akçali, C; Erbağci, Z, 2000)
"The effects of topical azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid (alpha-hydroxy acid) for acne are unclear."5.05Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review. ( Liu, G; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"To assess the effects of topical treatments (azelaic acid, salicylic acid, nicotinamide, zinc, alpha-hydroxy acid, and sulphur) for acne."5.05Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne. ( Liu, GJ; Liu, H; Liu, L; Peinemann, F; Sang, H; Xia, J; Yu, H, 2020)
"The treatment with the three salicylic acid-based products has been related to a significant improvement on acne lesions over 8 weeks of treatment, along with a reduction of personal discomfort related to acne and an improvement on lesions appearance."3.96Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study. ( Bettoli, V; Micali, G; Monfrecola, G; Veraldi, S, 2020)
"Glycolic acid is the smallest alpha hydroxy acid and widely used for skincare applications, including to treat acne vulgaris."3.96pH-Dependent Antibacterial Activity of Glycolic Acid: Implications for Anti-Acne Formulations. ( Cho, NJ; Jackman, JA; Mokrzecka, N; Valle-González, ER; Yoon, BK, 2020)
"We designed a prospective study to assess the efficacy of our serum composed of glycolic and salicylic acid for patients suffering from mild to moderate inflammatory and cystic acne, rosacea, folliculitis, and keratosis pilaris."3.96Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders. ( Haddad, L; Wiegmann, D, 2020)
"Glycolic acid (GA) and salicylic acid (SA) peels have been used separately for acne treatment, not as a sequential peel."3.96Sequential peeling as a monotherapy for treatment of milder forms of acne vulgaris. ( El Aguizy, RMS; Mahmoud, SB; Sabry, D; Sobhi, RM; Zayed, AA, 2020)
"To evaluate and compare the efficacy and safety therapy of glycolic acid (GA) peel, microneedling with dermapen and a combination of both procedures in treatment of atrophic acne scars."3.91Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study. ( El-Sayed, W; Esawy, AM; Kandeel, AH; Saadawi, AN, 2019)
"The standard management of acne vulgaris in Japan includes a combination of topical treatment with benzoyl peroxide (BPO) and BPO/clindamycin (CLDM), topical adapalene and systemic antimicrobials."3.85Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non-inflamed atrophic scars in acne vulgaris. ( Kawada, A; Kurokawa, I; Oiso, N, 2017)
"Many clinicians have used glycolic acid (GA) peels for facial acne, scarring, and hyperpigmentation, mainly in lighter skin types."3.75Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study. ( Garg, VK; Sarkar, R; Sinha, S, 2009)
"To compare the effects of 30% glycolic acid peels and Jessner's solution peels on sebum secretion in facial acne patients."3.73Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients. ( Huh, CH; Lee, SH; Park, KC; Youn, SW, 2006)
"To examine the potential anti-androgenic activity of anti-acne therapeutic agents, nadifloxacin (NDFX), RXM, all-trans retinoic acid (atRA), and glycolic acid (GA), we carried out the transient transfection assays using the CV-1 cells as a more sensitive assay system."3.72Modulation of androgen receptor transcriptional activity by anti-acne reagents. ( Inui, S; Itami, S; Nakao, T, 2004)
"Glycolic acid chemical peels are an effective treatment for all types of acne, inducing rapid improvement and restoration to normal looking skin."3.70Glycolic acid peeling in the treatment of acne. ( Atzori, L; Biggio, P; Brundu, MA; Orru, A, 1999)
"Glycolic acid has considerable therapeutic value for acne with minimal side effects even in Asian skin."3.69The effect of glycolic acid on the treatment of acne in Asian skin. ( Chan, HL; Hu, CT; Huang, CL; Wang, CM, 1997)
"The biggest hurdle in the treatment of acne vulgaris is patient non-compliance that is due in large part to poor tolerability to common acne medications."2.79Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients. ( Bhatia, AC; Jimenez, F, 2014)
"  Acne scars can cause emotional and psychosocial disturbance to the patient."2.76Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin. ( Sharad, J, 2011)
"Acne is one of the most frequent skin disorders that occurs in puberty, but often adults also have acne."2.52[Use of organic acids in acne and skin discolorations therapy]. ( Kapuścińska, A; Nowak, I, 2015)
"Many clinicians use these peels in the treatment of acne and acne-prone oily skin."2.47Expert opinion: efficacy of superficial chemical peels in active acne management--what can we learn from the literature today? Evidence-based recommendations. ( Berson, DS; Cohen, JL; Dréno, B; Fischer, TC; Perosino, E; Poli, F; Rendon, MI; Roberts, WE; Starker, I; Viera, MS; Wang, B, 2011)
"Acne vulgaris affects 3 out of 4 adolescents and usually vanishes at the end of puberty with either no sequelae or mild to moderate sequelae, such as postinflammatory hyperpigmenation (PIH), which may result in psychological and emotional damages."2.43RALGA (Diacneal), a retinaldehyde and glycolic acid association and postinflammatory hyperpigmentation in acne--a review. ( Katsambas, AD, 2005)
"Acne vulgaris is a common and chronic skin disease that impacts on physical and psychological perceptions."1.56Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary resul ( Annunziata, MC; Cinelli, E; Donnarumma, M; Fabbrocini, G; Milani, M; Villani, A, 2020)
"A 19-year-old Japanese man had been treated for ulcerative colitis for 2 years."1.37A case of acne fulminans in a patient with ulcerative colitis successfully treated with prednisolone and diaminodiphenylsulfone: a literature review of acne fulminans, rosacea fulminans and neutrophilic dermatoses occurring in the setting of inflammatory ( Danno, K; Fujimoto, N; Tanaka, T; Uenishi, T; Wakabayashi, M, 2011)

Research

Studies (53)

TimeframeStudies, this research(%)All Research%
pre-19901 (1.89)18.7374
1990's6 (11.32)18.2507
2000's14 (26.42)29.6817
2010's21 (39.62)24.3611
2020's11 (20.75)2.80

Authors

AuthorsStudies
Chen, L2
Lu, L1
Tu, S1
Zhang, T1
Du, X1
Zhang, M1
Li, L2
Lin, H1
Dayal, S1
Kaur, R1
Sahu, P1
Zhao, J1
Zhou, B1
Hou, Y1
Zhuo, F1
Zayed, AA1
Sobhi, RM1
El Aguizy, RMS1
Sabry, D1
Mahmoud, SB1
Wiegmann, D1
Haddad, L1
Liu, H2
Yu, H2
Xia, J2
Liu, L2
Liu, GJ1
Sang, H2
Peinemann, F2
Valle-González, ER1
Jackman, JA1
Yoon, BK1
Mokrzecka, N1
Cho, NJ1
Villani, A1
Annunziata, MC1
Cinelli, E1
Donnarumma, M1
Milani, M2
Fabbrocini, G1
Liu, G1
Bettoli, V1
Micali, G1
Monfrecola, G1
Veraldi, S1
Bertolani, MB1
Rodighiero, E1
Gandolfi, M1
Lotti, T1
Pedrazzi, G1
Puviani, M1
Feliciani, C1
Satolli, F1
Bulbul Baskan, E1
Tilki Günay, I1
Saricaoglu, H1
Rana, S1
Mendiratta, V1
Chander, R1
In Jae, J1
Dong Ju, H1
Dong Hyun, K1
Yoon, MS1
Lee, HJ1
Saadawi, AN1
Esawy, AM1
Kandeel, AH1
El-Sayed, W1
Kaminaka, C1
Uede, M1
Matsunaka, H1
Furukawa, F1
Yamomoto, Y1
Abels, C2
Reich, H1
Knie, U2
Werdier, D2
Lemmnitz, G1
Bhatia, AC1
Jimenez, F1
Masini, F1
Ricci, F1
Fossati, B1
Frascione, P1
Capizzi, R1
De Waure, C1
Guerriero, C1
Ash, C1
Harrison, A1
Drew, S1
Whittall, R1
Kapuścińska, A1
Nowak, I1
Kurokawa, I2
Oiso, N1
Kawada, A1
Barros, BS1
Zaenglein, AL1
Khunger, N1
Kempiak, SJ1
Uebelhoer, N1
Garg, VK1
Sinha, S1
Sarkar, R1
Dreno, B4
Castell, A1
Tsankov, N1
Lipozencic, J1
Serdaroglu, S1
Gutierrez, V1
Gadroy, A1
Merial-Kieny, C1
Mery, S1
Ilknur, T1
Demirtaşoğlu, M1
Biçak, MU1
Ozkan, S1
Fischer, TC1
Perosino, E1
Poli, F2
Viera, MS1
Rendon, MI1
Berson, DS1
Cohen, JL1
Roberts, WE1
Starker, I1
Wang, B1
Perić, S1
Bubanj, M1
Bubanj, S1
Jančić, S1
Wakabayashi, M1
Fujimoto, N1
Uenishi, T1
Danno, K1
Tanaka, T1
Wheeland, RG1
Dhawan, S1
Kaszuba, A2
Michalak, I1
Takenaka, Y1
Hayashi, N1
Takeda, M1
Ashikaga, S1
Kawashima, M1
Sharad, J1
Callender, VD1
Inui, S1
Nakao, T1
Itami, S1
Ribet, V2
Lauze, C1
Adhoute, H1
Morinet, P2
Nocera, T2
Verrière, F1
Vienne, MP1
Ségard, C1
Vitse, S1
Carré, C1
Kasraee, B1
Tran, C1
Sorg, O1
Saurat, JH1
Katsambas, AD1
Lee, SH1
Huh, CH1
Park, KC1
Youn, SW1
Katsambas, A1
Pelfini, C1
Plantier, D1
Jancovici, E1
Khammari, A1
Kessler, E1
Flanagan, K1
Chia, C1
Rogers, C1
Glaser, DA1
Clark, CP1
Fratila, A1
Wang, CM1
Huang, CL1
Hu, CT1
Chan, HL1
Apfelberg, DB1
Atzori, L1
Brundu, MA1
Orru, A1
Biggio, P1
Kim, SW1
Moon, SE1
Kim, JA1
Eun, HC1
Erbağci, Z1
Akçali, C1
Van Scott, EJ1
Yu, RJ1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Efficacy of Combined Peels in Treatment of Melasma Using Modified Jessner's Solution With 20%Trichloroacetic Acid Versus 70%Glycolic Acid With 20% Trichloroacetic Acid : A Split-face Study[NCT03153852]Phase 430 participants (Anticipated)Interventional2018-03-15Not yet recruiting
Knowledge Evaluation and Assessment of the Effectiveness of an Education Intervention on Acne[NCT01629797]100 participants (Actual)Interventional2012-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Correct Responses to Questionnaire Items Before and 2 Months After an Educational Lecture

In order to evaluate the long-term effect of an educational lecture about acne, subjects completed a questionnaire to assess knowledge about acne immediately before and two months after the educational lecture. The number of correct responses to each questionnaire item was calculated pre- and two months post-educational lecture. (NCT01629797)
Timeframe: before and 2 months after an educational lecture

,
Interventionparticipants (Number)
How to wash skinHow often to wash faceDiet affects acneDirt affects acneHair product affects acneSweat affects acneCosmetics affect acneMoisturizers affect acneHumidity affects acneSeason affects acneStress affects acneDrugs affect acneStress worsens acneDiet worsens acneMenses worsens acneHormones worsen acneGenetics worsen acneExcess oil causes acneClogged pores cause acneBacteria causes acneInflammation causes acneAcne can be curedResults of acne treatmentAcne treatment lastsAcne can scar skinCosmetics worsen acne
Pre-educational Lecture7974603145276140354477567230646848677770332938458279
Two Months Post-educational Lecture7876551265227658323677807725767963818277696547438077

Number of Correct Responses to Questionnaire Items Immediately Before and After and Educational Lecture

In order to evaluate the immediate effect of an educational lecture about acne, subjects completed a questionnaire to assess knowledge about acne immediately before and after the educational lecture. The number of correct responses to each questionnaire item was calculated pre- and post-educational lecture. (NCT01629797)
Timeframe: immediately before and after an educational lecture

,
Interventionparticipants (Number)
How to wash skinHow often to wash faceDiet affects acneDirt affects acneHair product affects acneSweat affects acneCosmetics affect acneMoisturizers affect acneHumidity affects acneSeason affects acneStress affects acneDrugs affect acneStress worsens acneDiet worsens acneMenses worsens acneHormones worsen acneGenetics worsen acneExcess oil causes acneClogged pores cause acneBacteria causes acneInflammation causes acneAcne can be curedResults of acne treatmentAcne treatment lastsAcne can scarCosmetics worsen acne
Post-educational Lecture7979433763436543536376507646777666778077706970618179
Pre-educational Lecture7974603145276140354472567230646848677770332938458279

Reviews

9 reviews available for glycolic acid and Acne

ArticleYear
Topical azelaic acid, salicylic acid, nicotinamide, sulphur, zinc and fruit acid (alpha-hydroxy acid) for acne.
    The Cochrane database of systematic reviews, 2020, 05-01, Volume: 5

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Bias; Child; C

2020
Evidence-based topical treatments (azelaic acid, salicylic acid, nicotinamide, sulfur, zinc, and fruit acid) for acne: an abridged version of a Cochrane systematic review.
    Journal of evidence-based medicine, 2020, Volume: 13, Issue:4

    Topics: Acne Vulgaris; Administration, Cutaneous; Dermatologic Agents; Dicarboxylic Acids; Fruit; Glycolates

2020
[Use of organic acids in acne and skin discolorations therapy].
    Postepy higieny i medycyny doswiadczalnej (Online), 2015, Mar-22, Volume: 69

    Topics: Acne Vulgaris; Adolescent; Adult; Child; Dermatitis; Female; Glycolates; Gram-Positive Bacterial Inf

2015
The Use of Cosmeceuticals in Acne: Help or Hoax?
    American journal of clinical dermatology, 2017, Volume: 18, Issue:2

    Topics: Acne Vulgaris; Complementary Therapies; Contraindications; Cosmeceuticals; Deception; Glycolates; Hu

2017
Superficial chemical peels and microdermabrasion for acne vulgaris.
    Seminars in cutaneous medicine and surgery, 2008, Volume: 27, Issue:3

    Topics: Acne Vulgaris; Dermabrasion; Glycolates; Humans; Keratolytic Agents; Salicylic Acid; Treatment Outco

2008
Expert opinion: efficacy of superficial chemical peels in active acne management--what can we learn from the literature today? Evidence-based recommendations.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2011, Volume: 25, Issue:6

    Topics: Acne Vulgaris; Chemexfoliation; Evidence-Based Medicine; Glycolates; Humans; Keratolytic Agents; Pyr

2011
Acne in ethnic skin: special considerations for therapy.
    Dermatologic therapy, 2004, Volume: 17, Issue:2

    Topics: Acne Vulgaris; Administration, Cutaneous; Administration, Oral; Anti-Bacterial Agents; Glycolates; H

2004
RALGA (Diacneal), a retinaldehyde and glycolic acid association and postinflammatory hyperpigmentation in acne--a review.
    Dermatology (Basel, Switzerland), 2005, Volume: 210 Suppl 1

    Topics: Acne Vulgaris; Adolescent; Dermatologic Agents; Drug Combinations; Drug Synergism; Glycolates; Human

2005
Alpha hydroxy acids in skin care.
    Clinics in plastic surgery, 1996, Volume: 23, Issue:1

    Topics: Acne Vulgaris; Chemexfoliation; Female; Glycolates; Humans; Hydroxy Acids; Male; Melanosis; Skin Agi

1996

Trials

21 trials available for glycolic acid and Acne

ArticleYear
Efficacy and safety of 5% glycolic acid-based Gel essence in the treatment of mild to moderate acne.
    Journal of cosmetic dermatology, 2022, Volume: 21, Issue:10

    Topics: Acne Vulgaris; Erythema; Female; Glycolates; Humans; Male; Treatment Outcome

2022
Efficacy of Microneedling With 35% Glycolic Acid Peels Versus Microneedling With 15% Trichloroacetic Acid Peels in Treatment of Atrophic Acne Scars: A Randomized Controlled Trial.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2022, 11-01, Volume: 48, Issue:11

    Topics: Acne Vulgaris; Atrophy; Cicatrix; Connective Tissue Diseases; Humans; Needles; Treatment Outcome; Tr

2022
Efficacy and tolerability of short contact therapy with tretinoin, clindamycin, and glycolic acid gel in acne: A randomized, controlled, assessor-blinded two-center trial: The MASCOTTE study.
    Dermatologic therapy, 2021, Volume: 34, Issue:1

    Topics: Acne Vulgaris; Adolescent; Adult; Clindamycin; Dermatologic Agents; Female; Gels; Glycolates; Humans

2021
Efficacy of peeling during different periods of the menstrual cycle on acne.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2017, Volume: 19, Issue:6

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Female; Glycolates; Humans; Menstrual Cycle; Ovulation; Young

2017
Efficacy of microneedling with 70% glycolic acid peel vs microneedling alone in treatment of atrophic acne scars-A randomized controlled trial.
    Journal of cosmetic dermatology, 2017, Volume: 16, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Atrophy; Chemexfoliation; Cicatrix; Combined Modality Therapy; Gly

2017
Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris.
    Journal of cosmetic dermatology, 2018, Volume: 17, Issue:5

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Drug Combinations; Drug Therapy, Combination; Esthetics; Etha

2018
Clinical evaluation of glycolic acid chemical peeling in patients with acne vulgaris: a randomized, double-blind, placebo-controlled, split-face comparative study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2014, Volume: 40, Issue:3

    Topics: Acne Vulgaris; Adult; Asian People; Chemexfoliation; Double-Blind Method; Female; Glycolates; Humans

2014
Significant improvement in mild acne following a twice daily application for 6 weeks of an acidic cleansing product (pH 4).
    Journal of cosmetic dermatology, 2014, Volume: 13, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Detergents; Female; Glycolates; Humans; Hydrogen-Ion Concentration

2014
Rapid treatment of mild acne with a novel skin care system containing 1% salicylic acid, 10% buffered glycolic acid, and botanical ingredients.
    Journal of drugs in dermatology : JDD, 2014, Volume: 13, Issue:6

    Topics: Acne Vulgaris; Administration, Cutaneous; Adolescent; Adult; Child; Dermatologic Agents; Female; Gly

2014
A randomized controlled study for the treatment of acne vulgaris using high-intensity 414 nm solid state diode arrays.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2015, Volume: 17, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Combined Modality Therapy; Cosmetic Techniques; Double-Blind Metho

2015
Glycolic acid peels versus amino fruit acid peels for acne.
    Journal of cosmetic and laser therapy : official publication of the European Society for Laser Dermatology, 2010, Volume: 12, Issue:5

    Topics: Acne Vulgaris; Amino Acids; Cosmetic Techniques; Face; Fruit; Glycolates; Humans; Image Processing,

2010
Side effects assessment in glicolyc acid peelings in patients with acne type I.
    Bosnian journal of basic medical sciences, 2011, Volume: 11, Issue:1

    Topics: Acne Vulgaris; Adolescent; Chemexfoliation; Dose-Response Relationship, Drug; Female; Glycolates; Hu

2011
Evaluation of self-treatment of mild-to-moderate facial acne with a blue light treatment system.
    Journal of drugs in dermatology : JDD, 2011, Volume: 10, Issue:6

    Topics: Acne Vulgaris; Adult; Combined Modality Therapy; Dermatologic Agents; Dicarboxylic Acids; Drug Combi

2011
A 10% glycolic acid containing oil-in-water emulsion improves mild acne: a randomized double-blind placebo-controlled trial.
    Journal of cosmetic dermatology, 2011, Volume: 10, Issue:3

    Topics: Acne Vulgaris; Adolescent; Adult; Child; Emulsions; Erythema; Female; Glycolates; Humans; Intention

2011
Combination of microneedling and glycolic acid peels for the treatment of acne scars in dark skin.
    Journal of cosmetic dermatology, 2011, Volume: 10, Issue:4

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Cicatrix; Combined Modality Therapy; Female; Glycolates; Huma

2011
Efficacy and safety of 0.1% retinaldehyde/ 6% glycolic acid (diacneal) for mild to moderate acne vulgaris. A multicentre, double-blind, randomized, vehicle-controlled trial.
    Dermatology (Basel, Switzerland), 2005, Volume: 210 Suppl 1

    Topics: Acne Vulgaris; Adolescent; Adult; Biopsy; Child; Dermatologic Agents; Double-Blind Method; Drug Comb

2005
Topical retinaldehyde with glycolic acid: study of tolerance and acceptability in association with anti-acne treatments in 1,709 patients.
    Dermatology (Basel, Switzerland), 2005, Volume: 210 Suppl 1

    Topics: Acne Vulgaris; Administration, Cutaneous; Adolescent; Adult; Child; Dermatologic Agents; Drug Combin

2005
Combined 0.1% retinaldehyde/ 6% glycolic acid cream in prophylaxis and treatment of acne scarring.
    Dermatology (Basel, Switzerland), 2007, Volume: 214, Issue:3

    Topics: Acne Vulgaris; Adolescent; Adult; Cicatrix; Female; Glycolates; Humans; Male; Ointments; Retinaldehy

2007
Comparison of alpha- and beta-hydroxy acid chemical peels in the treatment of mild to moderately severe facial acne vulgaris.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2008, Volume: 34, Issue:1

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Chemexfoliation; Double-Blind Method; Fac

2008
Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1999, Volume: 25, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe

1999
Biweekly serial glycolic acid peels vs. long-term daily use of topical low-strength glycolic acid in the treatment of atrophic acne scars.
    International journal of dermatology, 2000, Volume: 39, Issue:10

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Atrophy; Cicatrix; Dosage Forms; Drug Adm

2000

Other Studies

23 other studies available for glycolic acid and Acne

ArticleYear
Effect of 5% glycolic acid complex and 20% glycolic acid on mild-to-moderate facial acne vulgaris.
    Chinese medical journal, 2022, 11-05, Volume: 135, Issue:21

    Topics: Acne Vulgaris; Face; Glycolates; Humans; Treatment Outcome

2022
Sequential peeling as a monotherapy for treatment of milder forms of acne vulgaris.
    Journal of cosmetic dermatology, 2020, Volume: 19, Issue:6

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Female; Glycolates; Humans; Keratolytic Agents; M

2020
Two is better than one: The combined effects of glycolic acid and salicylic acid on acne-related disorders.
    Journal of cosmetic dermatology, 2020, Volume: 19, Issue:9

    Topics: Acne Vulgaris; Glycolates; Humans; Prospective Studies; Salicylic Acid; Treatment Outcome

2020
pH-Dependent Antibacterial Activity of Glycolic Acid: Implications for Anti-Acne Formulations.
    Scientific reports, 2020, 05-04, Volume: 10, Issue:1

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Glycolates; Humans; Hydrogen-Ion Concentration; Propionibacter

2020
Efficacy and safety of a new topical gel formulation containing retinol encapsulated in glycospheres and hydroxypinacolone retinoate, an antimicrobial peptide, salicylic acid, glycolic acid and niacinamide for the treatment of mild acne: preliminary resul
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2020, Volume: 155, Issue:5

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Anti-Infective Agents; Female; Gels; Glyc

2020
Effectiveness of a combination of salicylic acid-based products for the treatment of mild comedonal-papular acne: a multicenter prospective observational study.
    Giornale italiano di dermatologia e venereologia : organo ufficiale, Societa italiana di dermatologia e sifilografia, 2020, Volume: 155, Issue:6

    Topics: Acne Vulgaris; Adult; Carbamide Peroxide; Dermatologic Agents; Drug Combinations; Facial Dermatoses;

2020
Microneedling by dermapen and glycolic acid peel for the treatment of acne scars: Comparative study.
    Journal of cosmetic dermatology, 2019, Volume: 18, Issue:1

    Topics: Acne Vulgaris; Adult; Chemexfoliation; Cicatrix; Combined Modality Therapy; Cosmetic Techniques; Fem

2019
Combination therapy with retinaldehyde (0.1%) glycolic acid (6%) and efectiose (0.1%) in mild to moderate acne vulgaris during the period of sun exposure--efficacy and skin tolerability.
    European review for medical and pharmacological sciences, 2014, Volume: 18, Issue:16

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Child; Dermatologic Agents; Drug Combinations; F

2014
Case reports of adjuvant combination therapy in severe acne vulgaris with chemical peeling using glycolic acid and iontophoresis.
    The Journal of dermatology, 2015, Volume: 42, Issue:11

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Combined Modality Therapy; Female; Glycolates; Hu

2015
Adjuvant alternative treatment with chemical peeling and subsequent iontophoresis for postinflammatory hyperpigmentation, erosion with inflamed red papules and non-inflamed atrophic scars in acne vulgaris.
    The Journal of dermatology, 2017, Volume: 44, Issue:4

    Topics: Acne Vulgaris; Adapalene; Adolescent; Adult; alpha-Tocopherol; Anti-Infective Agents; Ascorbic Acid;

2017
Standard guidelines of care for chemical peels.
    Indian journal of dermatology, venereology and leprology, 2008, Volume: 74 Suppl

    Topics: Acne Vulgaris; Chemexfoliation; Glycolates; Humans; Skin; Skin Aging; Skin Diseases

2008
Glycolic acid peels versus salicylic-mandelic acid peels in active acne vulgaris and post-acne scarring and hyperpigmentation: a comparative study.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 2009, Volume: 35, Issue:1

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Cicatrix; Drug Combinations; Female; Glycolates;

2009
Interest of the association retinaldehyde/glycolic acid in adult acne.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2009, Volume: 23, Issue:5

    Topics: Acne Vulgaris; Administration, Topical; Adult; Drug Combinations; Female; Glycolates; Humans; Retina

2009
A case of acne fulminans in a patient with ulcerative colitis successfully treated with prednisolone and diaminodiphenylsulfone: a literature review of acne fulminans, rosacea fulminans and neutrophilic dermatoses occurring in the setting of inflammatory
    Dermatology (Basel, Switzerland), 2011, Volume: 222, Issue:3

    Topics: Acne Vulgaris; Anti-Inflammatory Agents; Biopsy; Cefozopran; Cephalosporins; Colitis, Ulcerative; Da

2011
Glycolic acid chemical peeling improves inflammatory acne eruptions through its inhibitory and bactericidal effects on Propionibacterium acnes.
    The Journal of dermatology, 2012, Volume: 39, Issue:4

    Topics: Acne Vulgaris; Adult; Agar; Bacterial Load; Chemexfoliation; Female; Glycolates; Humans; Keratolytic

2012
Modulation of androgen receptor transcriptional activity by anti-acne reagents.
    Journal of dermatological science, 2004, Volume: 36, Issue:2

    Topics: Acne Vulgaris; Androgen Antagonists; Animals; Cell Line; Dermatologic Agents; Fluoroquinolones; Glyc

2004
The depigmenting effect of RALGA in C57BL/6 mice.
    Dermatology (Basel, Switzerland), 2005, Volume: 210 Suppl 1

    Topics: Acne Vulgaris; Animals; Dermatologic Agents; Drug Combinations; Glycolates; Hyperpigmentation; Kerat

2005
Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 2006, Volume: 20, Issue:8

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe

2006
[Alpha-hydroxy acid treatment in acne therapy].
    Der Hautarzt; Zeitschrift fur Dermatologie, Venerologie, und verwandte Gebiete, 1996, Volume: 47, Issue:12

    Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Hydroxy Acids; Skin Pigmentation; Sugar

1996
The effect of glycolic acid on the treatment of acne in Asian skin.
    Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.], 1997, Volume: 23, Issue:1

    Topics: Acne Vulgaris; Adolescent; Adult; Asia; Chemexfoliation; Cicatrix; Cysts; Erythema; Female; Glycolat

1997
Ultrapulse carbon dioxide laser with CPG scanner for full-face resurfacing for rhytids, photoaging, and acne scars.
    Plastic and reconstructive surgery, 1997, Volume: 99, Issue:7

    Topics: Acne Vulgaris; Acyclovir; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents; Antiviral Agents

1997
Glycolic acid peeling in the treatment of acne.
    Journal of the European Academy of Dermatology and Venereology : JEADV, 1999, Volume: 12, Issue:2

    Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Cicatrix; Female; Glycolates; Humans; Keratolytic

1999
Alpha hydroxy acids: procedures for use in clinical practice.
    Cutis, 1989, Volume: 43, Issue:3

    Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic

1989