Compounds > topterone
Page last updated: 2024-12-11

topterone

Description Research Excerpts Clinical Trials Roles Classes Pathways Study Profile Bioassays Related Drugs Related Conditions Protein Interactions Research Growth Market Indicators

Description

topterone: structure [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID9797605
CHEMBL ID2107659
SCHEMBL ID3844149
MeSH IDM0079702

Synonyms (27)

Synonym
topterone (usan/inn)
60607-35-4
D06191
topterone
androst-4-en-3-one, 17-hydroxy-17-propyl-, (17beta)-
einecs 262-321-4
win 17665
unii-77wpb17zk1
17beta-hydroxy-17-propylandrost-4-en-3-one
topteronum
(17beta)-17-hydroxy-17-propylandrost-4-en-3-one
topterona
77wpb17zk1 ,
topteronum [inn-latin]
topterona [inn-spanish]
topterone [usan:inn]
CHEMBL2107659
win-17665
topterone [inn]
topterone [usan]
SCHEMBL3844149
DTXSID20209417
HY-U00198
CS-7298
Q15633967
(8r,9s,10r,13s,14s,17s)-17-hydroxy-10,13-dimethyl-17-propyl-2,6,7,8,9,11,12,14,15,16-decahydro-1h-cyclopenta[a]phenanthren-3-one
AKOS040740440

Research Excerpts

Dosage Studied

ExcerptRelevanceReference
" They also indicate that the topical administration of effective dosage levels of L-651,580 causes few, if any, systemic effects."( Topical anti-androgenicity of a new 4-azasteroid in the hamster.
Berman, C; Brooks, JR; Krupa, DA; Primka, RL; Rasmusson, GH; Reynolds, GF, 1991)		0.28
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research

Studies (5)

TimeframeStudies, This Drug (%)All Drugs %
pre-19904 (80.00)18.7374
1990's1 (20.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Market Indicators

Research Demand Index: 12.36

According to the monthly volume, diversity, and competition of internet searches for this compound, as well the volume and growth of publications, there is estimated to be weak demand-to-supply ratio for research on this compound.

MetricThis Compound (vs All)
Research Demand Index12.36 (24.57)
Research Supply Index1.95 (2.92)
Research Growth Index4.31 (4.65)
Search Engine Demand Index0.00 (26.88)
Search Engine Supply Index0.00 (0.95)

This Compound (12.36)

All Compounds (24.57)

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials1 (20.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other4 (80.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]
SubstanceRelationship StrengthStudiesTrialsClassesRoles
dihydrotestosterone
Dihydrotestosterone: A potent androgenic metabolite of TESTOSTERONE. It is produced by the action of the enzyme 3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE.. 17beta-hydroxyandrostan-3-one : A 17beta-hydroxy steroid that is testosterone in which the 4-5 double bond has been reduced to a single bond with unspecified configuration at position 5.. 17beta-hydroxy-5alpha-androstan-3-one : A 17beta-hydroxy steroid that is testosterone in which the 4,5 double bond has been reduced to a single bond with alpha-configuration at position 5.		2.372017beta-hydroxy steroid;
17beta-hydroxyandrostan-3-one;
3-oxo-5alpha-steroid		androgen;
Daphnia magna metabolite;
human metabolite;
mouse metabolite
dihydrotestosterone propionate
dihydrotestosterone propionate: RN given refers to (5alpha,17beta)-isomer; structure		1.9710
mesterolone
Mesterolone: 17 beta-Hydroxy-1 alpha-methyl-5 alpha-androstan-3-one. A synthetic steroid with anabolic and androgenic activities.		1.97103-oxo-5alpha-steroid
17-propylmesterolone
17-propylmesterolone: under investigation as a topical anti-androgen for treatment of acne & seborrhea		1.9710
ConditionIndicatedRelationship StrengthStudiesTrials
Acne
[description not available]		03.7521
Acne Vulgaris
A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.		03.7521
Disease Models, Animal
Naturally-occurring or experimentally-induced animal diseases with pathological processes analogous to human diseases.		03.3611