Compounds > aspirin, butalbital and caffeine drug combination
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aspirin, butalbital and caffeine drug combination

Description

aspirin, butalbital and caffeine drug combination: combination drug of butalbital, caffeine and aspirin [MeSH]

Cross-References

ID SourceID
PubMed CID24847961
MeSH IDM0041327

Synonyms (19)

Synonym
51005-25-5
aspirin and caffeine w/ butalbital
butal compound
butalbital, aspirin and caffeine
butalbital w/ aspirin & caffeine
butalbital compound
butalbital aspirin and caffeine
aspirin, butalbital, caffeine drug combination
dolomo
aspirin - butalbital - caffeine
aspirin, butalbital and caffeine drug combination
butalbital, aspirin, and caffeine
benzoic acid, 2-(acetyloxy)-, mixt. with 3,7-dihydro-1,3,7-trimethyl-1h-purine-2,6-dione, and 5-(2-methylpropyl)-5-(2-propenyl)-2,4,6(1h,3h,5h)-pyrimidinetrione
b-a-c
marnal
fiorgen pf
isollyl improved
2-acetyloxybenzoic acid;5-(2-methylpropyl)-5-prop-2-enyl-1,3-diazinane-2,4,6-trione;1,3,7-trimethylpurine-2,6-dione
2-acetoxybenzoic acid compound with 1,3,7-trimethyl-3,7-dihydro-1h-purine-2,6-dione and 5-allyl-5-isobutylpyrimidine-2,4,6(1h,3h,5h)-trione (1:1:1)

Research

Studies (19)

TimeframeStudies, This Drug (%)All Drugs %
pre-199011 (57.89)18.7374
1990's6 (31.58)18.2507
2000's2 (10.53)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials5 (25.00%)5.53%
Reviews0 (0.00%)6.00%
Case Studies5 (25.00%)4.05%
Observational0 (0.00%)0.25%
Other10 (50.00%)84.16%
SubstanceStudiesClassesRolesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
niacinamide
1
pyridine alkaloid;
pyridinecarboxamide;
vitamin B3		anti-inflammatory agent;
antioxidant;
cofactor;
EC 2.4.2.30 (NAD(+) ADP-ribosyltransferase) inhibitor;
EC 3.5.1.98 (histone deacetylase) inhibitor;
Escherichia coli metabolite;
geroprotector;
human urinary metabolite;
metabolite;
mouse metabolite;
neuroprotective agent;
Saccharomyces cerevisiae metabolite;
Sir2 inhibitor		1992199232.0low001000
acetaminophen
1
acetamides;
phenols		antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
cyclooxygenase 3 inhibitor;
environmental contaminant;
ferroptosis inducer;
geroprotector;
hepatotoxic agent;
human blood serum metabolite;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
xenobiotic		2005200519.0low100100
amobarbital
1
barbiturates1992199232.0low001000
aspirin
19
benzoic acids;
phenyl acetates;
salicylates		anticoagulant;
antipyretic;
cyclooxygenase 1 inhibitor;
cyclooxygenase 2 inhibitor;
drug allergen;
EC 1.1.1.188 (prostaglandin-F synthase) inhibitor;
geroprotector;
non-narcotic analgesic;
non-steroidal anti-inflammatory drug;
plant activator;
platelet aggregation inhibitor;
prostaglandin antagonist;
teratogenic agent		1953200538.0high4116200
caffeine
19
purine alkaloid;
trimethylxanthine		adenosine A2A receptor antagonist;
adenosine receptor antagonist;
adjuvant;
central nervous system stimulant;
diuretic;
EC 2.7.11.1 (non-specific serine/threonine protein kinase) inhibitor;
EC 3.1.4.* (phosphoric diester hydrolase) inhibitor;
environmental contaminant;
food additive;
fungal metabolite;
geroprotector;
human blood serum metabolite;
mouse metabolite;
mutagen;
plant metabolite;
psychotropic drug;
ryanodine receptor agonist;
xenobiotic		1953200538.0high4116200
chlordiazepoxide
1
benzodiazepine1992199232.0low001000
imipramine
1
dibenzoazepineadrenergic uptake inhibitor;
antidepressant;
EC 3.4.21.26 (prolyl oligopeptidase) inhibitor		1991199133.0low001000
meperidine
1
ethyl ester;
piperidinecarboxylate ester;
tertiary amino compound		antispasmodic drug;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic		1992199232.0low001000
phenacetin
13
acetamides;
aromatic ether		cyclooxygenase 3 inhibitor;
non-narcotic analgesic;
peripheral nervous system drug		1982199735.5medium385000
phenobarbital
1
barbituratesanticonvulsant;
drug allergen;
excitatory amino acid antagonist;
sedative		1985198539.0low010000
secobarbital
1
barbituratesanaesthesia adjuvant;
GABA modulator;
sedative		1992199232.0low001000
ergotamine
1
peptide ergot alkaloidalpha-adrenergic agonist;
mycotoxin;
non-narcotic analgesic;
oxytocic;
serotonergic agonist;
vasoconstrictor agent		1984198440.0low010000
ephedrine
1
phenethylamine alkaloid;
phenylethanolamines		bacterial metabolite;
environmental contaminant;
nasal decongestant;
plant metabolite;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic		1992199232.0low001000
methamphetamine
1
amphetamines;
secondary amine		central nervous system stimulant;
environmental contaminant;
neurotoxin;
psychotropic drug;
xenobiotic		1992199232.0low001000
diphenoxylate
1
ethyl ester;
nitrile;
piperidinecarboxylate ester;
tertiary amine		antidiarrhoeal drug1992199232.0low001000
isometheptene
1
secondary amino compound1984198440.0low010000
eletriptan
1
indoles;
N-alkylpyrrolidine;
sulfone		non-steroidal anti-inflammatory drug;
serotonergic agonist;
vasoconstrictor agent		2005200519.0low100100
cocaine
1
benzoate ester;
methyl ester;
tertiary amino compound;
tropane alkaloid		adrenergic uptake inhibitor;
central nervous system stimulant;
dopamine uptake inhibitor;
environmental contaminant;
local anaesthetic;
mouse metabolite;
plant metabolite;
serotonin uptake inhibitor;
sodium channel blocker;
sympathomimetic agent;
vasoconstrictor agent;
xenobiotic		1992199232.0low001000
codeine
4
morphinane alkaloid;
organic heteropentacyclic compound		antitussive;
drug allergen;
environmental contaminant;
opioid analgesic;
opioid receptor agonist;
prodrug;
xenobiotic		1985198837.5low340000
oxycodone
1
organic heteropentacyclic compound;
semisynthetic derivative		antitussive;
mu-opioid receptor agonist;
opioid analgesic		1985198539.0low010000
butorphanol
1
morphinane alkaloidantitussive;
kappa-opioid receptor agonist;
mu-opioid receptor agonist;
opioid analgesic		1999199925.0low001000
heroin
1
morphinane alkaloidmu-opioid receptor agonist;
opioid analgesic;
prodrug		1992199232.0low001000
ConditionIndicatedStudiesFirst YearLast YearAverage AgeRelationship StrengthTrialspre-19901990's2000's2010'spost-2020
Abdominal Migraine0
3
1984200530.7low111100
Ache0
5
1957199652.2low041000
Acute Post-operative Pain0
1
1985198539.0low010000
Anorexia Nervosa0
1
2005200519.0low000100
Anxiety0
1
1987198737.0low110000
Atypical Cluster Headache0
1
1984198440.0low010000
Bilateral Headache0
6
1953199941.2low351000
Body Weight0
1
2005200519.0low000100
Calcification, Pathologic0
1
1985198539.0low010000
Calcinosis0
1
1985198539.0low010000
Cardiac Failure0
1
2005200519.0low000100
Chemical Dependence0
3
1985200530.3low011100
Chronic Kidney Failure0
1
2005200519.0low000100
Costen's Syndrome0
1
1984198440.0low010000
Dissociation0
1
1991199133.0low001000
Drug-Induced Stevens Johnson Syndrome0
1
1982198242.0low010000
Essential Polyarteritis0
1
1982198242.0low010000
Headache0
6
1953199941.2low351000
Heart Failure0
1
2005200519.0low000100
Kidney Failure, Chronic0
1
2005200519.0low000100
Migraine Disorders0
3
1984200530.7low111100
Muscle Contraction0
1
1986198638.0low110000
Muscle Disorders0
1
1988198836.0low110000
Muscular Diseases0
1
1988198836.0low110000
Odontalgia0
1
1996199628.0low001000
Pain0
5
1957199652.2low041000
Pain, Postoperative0
1
1985198539.0low010000
Pregnancy0
1
1964196460.0low010000
Puerperal Disorders0
1
1964196460.0low010000
Recrudescence0
1
2005200519.0low000100
Stevens-Johnson Syndrome0
1
1982198242.0low010000
Substance-Related Disorders0
3
1985200530.3low011100
Tendinitis0
1
1985198539.0low010000
Tendinopathy0
1
1985198539.0low010000
Tooth Diseases0
1
1985198539.0low010000
Toothache0
1
1996199628.0low001000
Water-Electrolyte Imbalance0
1
2005200519.0low000100

Dosage (1)

ArticleYear
Comparison of butorphanol nasal spray and fiorinal with codeine in the treatment of migraine.
Headache, , Volume: 38, Issue:7