acetaminophen has been researched along with Acute Post-operative Pain in 1630 studies
Acetaminophen: Analgesic antipyretic derivative of acetanilide. It has weak anti-inflammatory properties and is used as a common analgesic, but may cause liver, blood cell, and kidney damage.
paracetamol : A member of the class of phenols that is 4-aminophenol in which one of the hydrogens attached to the amino group has been replaced by an acetyl group.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Among patients with cancer pain on strong opioid regime, acetaminophen may not improve pain control, or decrease total opioid use." | 9.69 | Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial. ( Castellano, J; González, A; Leiva-Vásquez, O; Letelier, LM; Pérez-Cruz, PE; Rojas, L; Viviani, P, 2023) |
| "This study aims to evaluate the efficacy and safety of multiple or single-dosage intravenous ibuprofen (IVIB) in managing postoperative pain and fever in adults who are unable to take oral medications." | 9.41 | Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta-analysis of randomized controlled trials. ( Chen, L; He, L; Tian, S; Wang, E; Zhai, S; Zhou, P, 2023) |
| "The study aimed to compare the acetaminophen administration efficacy or its combination with codeine for pain control in acute apical abscesses cases." | 9.41 | Comparison between isolated and associated with codeine acetaminophen in pain control of acute apical abscess: a randomized clinical trial. ( Cardoso, MBF; da Rosa, RA; da Silva, PB; do Nascimento, AL; Mendes, AT; Pereira, JR; Só, MVR, 2021) |
| " Eligible patients (male and female subjects, aged 18-65 years, reporting pain intensity levels ≥40 mm on a 100-mm visual analog scale (VAS) after distal, first metatarsal bunionectomy) were randomized (3:3:3:2) to receive the FDC (ibuprofen 300 mg + acetaminophen 1000 mg), ibuprofen 300 mg, acetaminophen 1000 mg, or placebo (vehicle), administered as 15-minute intravenous infusions every 6 hours for 48 hours." | 9.30 | Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial. ( Atkinson, HC; Daniels, SE; Gottlieb, IJ; Playne, R; Stanescu, I; Zhang, J, 2019) |
| " With evidence suggesting that intravenous acetaminophen (IVA) can be an opioid sparing option, we conducted a prospective, randomized trial that evaluated the effect of IVA on the postoperative pain course of children with perforated appendicitis." | 9.30 | Does Intravenous Acetaminophen Improve Postoperative Pain Control after Laparoscopic Appendectomy for Perforated Appendicitis? A Prospective Randomized Trial. ( Desai, AA; Doyle, NM; Fraser, JD; Gonzalez, KW; Millspaugh, DL; Poola, AS; Sola, R; St Peter, SD; Weaver, KL, 2019) |
| "To evaluate the prevention of opioid-induced nausea and vomiting (OINV) and the relief of moderate to severe acute pain by CL-108, a novel drug combining a low-dose antiemetic (rapid-release promethazine 12." | 9.30 | Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi ( Chou, JC; Daniels, SE; Giannakopoulos, HE; Granquist, EJ; Levin, LM; Maibach, H; Muse, DD; Oreadi, D; Papas, AS; Patrick, K; Schachtel, BP; Zuniga, JR, 2019) |
| "To compare the effect of preoperative intravenous (IV) acetaminophen compared with placebo on pain scores after pelvic organ prolapse surgery." | 9.30 | Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. ( Shepherd, JP; Turner, LC; Zyczynski, HM, 2019) |
| "We evaluated the efficacy of oral administration of a mixture of diosmin, coumarin glycosides, and Centella asiatica (Venoplant®) in preventing bleeding, pain, and thrombosis of internal and external hemorrhoids after stapled anopexy (SA)." | 9.24 | Effect of a mixture of diosmin, coumarin glycosides, and triterpenes on bleeding, thrombosis, and pain after stapled anopexy: a prospective, randomized, placebo-controlled clinical trial. ( Cipolat Mis, T; Del Giudice, R; Nicolì, F; Schiano di Visconte, M, 2017) |
| "The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery." | 9.24 | Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017) |
| "A fixed-dose combination biphasic immediate-release (IR)/extended-release (ER) hydrocodone bitartrate (HB)/acetaminophen (APAP) tablet is being developed for the management of acute pain severe enough to require opioid treatment and for which alternative treatment options are inadequate." | 9.20 | Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen tablets for acute postoperative pain. ( Barrett, T; Chen, Y; Giuliani, MJ; Kostenbader, K; Margulis, R; Singla, N; Young, JL; Zheng, Y, 2015) |
| "To assess opioid-sparing effects of oral or intravenous acetaminophen following primary cleft palate repair in children." | 9.19 | Analgesic effectiveness of acetaminophen for primary cleft palate repair in young children: a randomized placebo controlled trial. ( Applegate, RL; Hassanian, M; Martin, M; Mason, L; Nour, C; Ratsiu, J; Ray, A; Singh, N; Uhler, J, 2014) |
| "The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery." | 9.19 | Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. ( Durmus, E; Eroglu, CN; Kiresi, D, 2014) |
| "We sought to compare the efficacy and safety profiles of aspirin, acetaminophen with codeine, and placebo in the treatment of post-operative dental pain and tension-type headache." | 9.16 | Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension-type headache and postoperative dental pain. ( Fisher, M; Gatoulis, SC; Voelker, M, 2012) |
| "Pregabalin in the doses given decreased morphine requirements for the first 48 h postoperatively, but neither altered the analgesic requirements beyond 48 h nor had any effect on acute, late or chronic pain." | 9.16 | Perioperative pregabalin for acute and chronic pain after abdominal hysterectomy or myomectomy: a randomised controlled trial. ( Fassoulaki, A; Melemeni, A; Paraskeva, A; Tsaroucha, A, 2012) |
| "To assess clinical equivalence of 20 mg controlled-release oxycodone (Oxygesic; Mundipharma, Limburg, Germany) and 200 mg controlled-release tramadol (Tramal long; Grunenthal, Aachen, Germany) on a 12-hour dosing schedule in a randomized, double-blinded study of 54 ASA I-III physical status (American Society of Anesthesiologists classification of physical status) patients undergoing surgery for breast cancer." | 9.14 | Clinical equivalence of controlled-release oxycodone 20 mg and controlled-release tramadol 200 mg after surgery for breast cancer. ( Dagtekin, O; Kampe, S; Landwehr, S; Shaheen, S; Warm, M; Wolter, K, 2009) |
| "In this prospective, randomized, double-blinded study we sought to evaluate the efficacy and safety of combined use of intravenous ketorolac and acetaminophen in small children undergoing outpatient inguinal hernia repair." | 9.14 | Fentanyl sparing effects of combined ketorolac and acetaminophen for outpatient inguinal hernia repair in children. ( Hong, JY; Kil, HK; Kim, WO; Won Han, S, 2010) |
| "To assess clinical efficacy of IV paracetamol 1 g and IV dipyrone 1 g on a 24-h dosing schedule in this randomised, double-blinded study of 40 ASA I-III (American Society of Anesthesiologists classification of physical status) patients undergoing surgery for breast cancer." | 9.12 | Clinical equivalence of IV paracetamol compared to IV dipyrone for postoperative analgesia after surgery for breast cancer. ( Dagtekin, O; Haussmann, S; Kampe, S; Kiencke, P; Landwehr, S; Paul, M; Pilgram, B; Warm, M, 2006) |
| "The aim of the study is to evaluate the efficacy of post-incisional wound infiltration with levobupivacaine in preventing the postoperative pain associated with inguinal hernia repair in children." | 9.12 | Wound infiltration with levobupivacaine: an alternative method of postoperative pain relief after inguinal hernia repair in children. ( Kostopanagiotou, G; Matsota, P; Papageorgiou-Brousta, M, 2007) |
| "Acetaminophen decreases post-thoracotomy ipsilateral shoulder pain when given preemptively and regularly during the first 48 hours postoperatively in patients who received thoracic epidural analgesia." | 9.11 | Acetaminophen decreases early post-thoracotomy ipsilateral shoulder pain in patients with thoracic epidural analgesia: a double-blind placebo-controlled study. ( Boudreault, D; Chouinard, P; Ferraro, P; Girard, F; Lafontaine, ER; Mac, TB; Ruel, M, 2005) |
| "Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery." | 9.10 | Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002) |
| "To determine the efficacy of oral granisetron in preventing postoperative vomiting (POV) following strabismus repair in children." | 9.09 | Oral granisetron for strabismus surgery in children. ( D'Errico, CC; Lauder, GR; Munro, HM; Tait, AR; Voepel-Lewis, T; Wagner, DS, 1999) |
| "This randomized, double-blind, placebo-controlled study compared the time to onset of analgesia and the analgesic efficacy of two formulations of acetaminophen 1000 mg--an effervescent solution and tablet--in 242 patients with moderate or severe pain following dental surgery." | 9.09 | Time to onset of analgesia and analgesic efficacy of effervescent acetaminophen 1000 mg compared to tablet acetaminophen 1000 mg in postoperative dental pain: a single-dose, double-blind, randomized, placebo-controlled study. ( Ganry, HE; Insuasty, JH; Møller, PL; Nørholt, SE; Sindet-Pedersen, S; Skoglund, LA; Vincent, FG, 2000) |
| "Rectal acetaminophen (Ac) is often administered prophylactically at anesthesia induction for postoperative pain management in small children and is thought to have an opioid-sparing effect." | 9.09 | Prophylactically-administered rectal acetaminophen does not reduce postoperative opioid requirements in infants and small children undergoing elective cleft palate repair. ( Behne, M; Bremerich, DH; Heimann, K; Kessler, P; Neidhart, G, 2001) |
| " This study has attempted to assess postoperative analgesic consumption and nausea and vomiting after general anaesthesia for tonsillectomy using either paracetamol premedication, paracetamol plus a NSAID or intravenous morphine to provide postoperative analgesia." | 9.08 | Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques. ( Mather, SJ; Peutrell, JM, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 9.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "A prospective, comparative, randomized study to assess rectal acetaminophen (n = 45) to intravenous fentanyl-droperidol (n = 45) to resolve recovery profile, emesis rate, and adequacy of analgesia in a pediatric strabismus repair population was performed, with standardization of the anesthetic technique." | 9.08 | Comparison of postoperative emesis, recovery profile, and analgesia in pediatric strabismus repair. Rectal acetaminophen versus intravenous fentanyl-droperidol. ( Cruz, OA; Krock, JL; Padda, GS, 1997) |
| "Recognizing the concerns about the use of local anesthesia in neonatal circumcision, a painful procedure usually performed without analgesia or anesthesia, we undertook a study of acetaminophen for pain management of this procedure." | 9.07 | Acetaminophen analgesia in neonatal circumcision: the effect on pain. ( Howard, CR; Howard, FM; Weitzman, ML, 1994) |
| " The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus." | 9.07 | Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. ( Morrison, NA; Repka, MX, 1994) |
| "At Helsinki University Central Hospital in Finland, clinical researchers divided 169 women into two groups (group 1: diagnostic laparoscopies; group 2: laparoscopic sterilizations) as part of a study to evaluate the effect of intravenous diclofenac on postoperative pain, nausea, and recovery after outpatient gynecological laparoscopy." | 9.07 | Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy. ( Hovorka, J; Kallela, H; Korttila, K, 1993) |
| "We compared naproxen sodium (550 mg) and propoxyphene napsylate with acetaminophen (PN/A, 100 mg with 650 mg) for pain relief after arthroscopy or arthroscopic meniscectomy." | 9.06 | Pain relief after arthroscopy: naproxen sodium compared to propoxyphene napsylate with acetaminophen. ( Drez, D; Ritter, M; Rosenberg, TD, 1987) |
| "The anxiety and pain-relieving effect of paracetamol 10 mg/kg or a combination of aminophenazone 4 mg/kg and diazepam 0." | 9.05 | Comparison of paracetamol and aminophenazone plus diazepam suppositories for anxiety and pain relief after tonsillectomy in children. ( Lindgren, L; Saarnivaara, L, 1985) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 8.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 8.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "The inclusion criteria were: full journal publication, clinical trial, random allocation of adult patients to treatment groups, double blind design, moderate to severe baseline pain, postoperative administration of study drugs, treatment arms which included oxycodone or oxycodone plus paracetamol and placebo (or active control for which comparable efficacy data exist), and oral, intramuscular or intravenous administration of study drugs." | 8.80 | Single dose oxycodone and oxycodone plus paracetamol (acetominophen) for acute postoperative pain. ( Edwards, JE; McQuay, HJ; Moore, RA, 2000) |
| "In order to assess the analgesia obtained from single oral doses of paracetamol alone and in combination with codeine in postoperative pain, we conducted a systematic review of randomised controlled trials." | 8.79 | Paracetamol with and without codeine in acute pain: a quantitative systematic review. ( Carroll, D; Collins, S; McQuay, H; Moore, A, 1997) |
| "Opioid analgesia for acute painful conditions has come under increasing scrutiny with the public health crisis of opioid overdose, leading clinicians to seek nonopioid alternatives, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (paracetamol)." | 8.02 | Can NSAIDs and Acetaminophen Effectively Replace Opioid Treatment Options for Acute Pain? ( Breve, F; LeQuang, JA; Magnusson, P; Pergolizzi, JV; Taylor, R; Varrassi, G; Wollmuth, C, 2021) |
| "The goal of this prospective cohort study was to model cost-effectiveness of adding acetaminophen or acetaminophen + ketorolac to opioids for postoperative outcomes in children having scoliosis surgery." | 7.88 | Cost-effectiveness of intravenous acetaminophen and ketorolac in adolescents undergoing idiopathic scoliosis surgery. ( Chidambaran, V; Ding, L; Eckman, MH; Geisler, K; Jain, V; Sadhasivam, S; Stubbeman, B; Sturm, P; Subramanyam, R, 2018) |
| "The objective of this study was to determine: 1) the incidence and the risk factors of diclofenac/acetaminophen combination as a single agent induced Acute Kidney Injury (AKI) in postoperative pain relief 2) the average cost and length of hospital stay for patients in AKI group and non-AKI group." | 7.88 | Diclofenac--Acetaminophen Combination Induced Acute Kidney Injury In Postoperative Pain Relief. ( Banh, HL; Cave, A; Li, YY; Luo, JQ; Wang, Q; Xiao, YW; Xu, P; Zhou, YG; Zhu, Y, 2018) |
| "Trials in acute postoperative pain are usually small." | 7.80 | Meta-analysis of single dose oral tramadol plus acetaminophen in acute postoperative pain. ( Edwards, J; McQuay, H, 2003) |
| "A retrospective review of cleft palate cases over a 1-year period, 6 months with hemostatic pledgets, and 6 months with bupivacaine-soaked hemostatic pledgets." | 7.77 | Does use of bupivacaine-soaked pledgets aid in the care of postoperative cleft palate patients? ( Burstein, FD; Otterburn, DM, 2011) |
| " Paracetamol has a very flat analgesic dose-response profile." | 7.01 | Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study. ( Lyngstad, G; Skjelbred, P; Skoglund, LA; Swanson, DM, 2021) |
| " Pain at rest/motion (based on pain visual analog scale (VAS) score), rescue analgesia consumption, satisfaction level and adverse events were assessed after AKS." | 7.01 | Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. ( Di, J; Liu, J; Xing, E; Zhang, Y, 2021) |
| "PONV was assessed in recovery and 24 hours after surgery in the ward." | 7.01 | Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. ( Aghabagheri, M; Khajavi, MR; Najjari, K; Pourfakhr, P; Talebpour, M; Zabihi Mahmoudabadi, H, 2021) |
| " When compared with placebo, total rescue opioid consumption was similar and significantly fewer intravenous acetaminophen patients prematurely discontinued because of treatment-emergent adverse events (P < ." | 6.94 | Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants. ( Cooper, DS; Devarakonda, K; Gosselin, NH; Hammer, GB; Lu, J; Maxwell, LG; Pheng, LH; Szmuk, P; Taicher, BM; Visoiu, M, 2020) |
| "Secondary outcome measures are postoperative pain intensity scores, psychological parameters, length of hospital stay and adverse events and will be reassessed at 3 and 6 months after surgery, with a baseline measurement preoperatively." | 6.90 | Assessing the effectiveness of perioperative s-ketamine on new-onset headache after resective epilepsy surgery (ESPAIN-trial): protocol for a randomised, double-blind, placebo-controlled trial. ( Bastiaenen, C; Bos, M; Colon, A; Dings, J; Hoogland, G; Rijkers, K; Rouhl, RPW; Schijns, OEMG; Sloekers, JCT; Theunissen, M; van Kuijk, S, 2019) |
| "To reduce postoperative pain by using additional analgesic agent in between the usual parenteral analgesia that is used in the postoperative period in surgical patients." | 6.87 | Effectiveness of acetaminophen in control of breakthrough pain: Randomized controlled trial. ( Bangash, AA; Durrani, Z, 2018) |
| " Secondary endpoints included SPID at additional time points, total pain relief at all on-therapy time points (TOTPAR), sum of SPID and TOTPAR at all on-therapy time points (SPID + TOTPAR), use of rescue medication, subjective pain assessment (PGIC, Patient Global Impression of Change), and adverse events (AEs)." | 6.80 | A randomized study to compare the efficacy and safety of extended-release and immediate-release tramadol HCl/acetaminophen in patients with acute pain following total knee replacement. ( Bin, SI; Chang, N; Cho, SD; Choi, CH; Ha, CW; Kang, SB; Kyung, HS; Lee, JH; Lee, MC; Park, YB; Rhim, HY; Seo, SS, 2015) |
| "Postoperative pain was assessed regularly with the Children Hospital of Eastern Ontario Pain Scale, and rescue analgesia was provided if scores were 7 or greater." | 6.76 | Effect of rectal diclofenac and acetaminophen alone and in combination on postoperative pain after cleft palate repair in children. ( Makarem, J; Mireskandari, SM, 2011) |
| " The outcome measures of interest in the meta-analysis were ≥ 50% pain relief , need for rescue medications, and occurrence of adverse drug events." | 6.72 | Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis. ( Abushanab, D; Al-Badriyeh, D, 2021) |
| " Mean total pain relief and the sum of pain intensity difference were also similar in the early period after dosing (0-4 hours)." | 6.71 | Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model. ( Cha, IH; Jung, YS; Kim, DK; Kim, HJ; Kim, MK; Lee, EW, 2004) |
| "Within the first 12 h after inguinal hernia repair in adult patients, a single injection of parecoxib 40 mg compares favorably with 2 injections of propacetamol 2 g." | 6.71 | A randomized, double-blind comparison between parecoxib sodium and propacetamol for parenteral postoperative analgesia after inguinal hernia repair in adult patients. ( Baechle, JP; Beaussier, M; Buffin, A; Didelot, JP; Goater, P; Lavazais, S; Lienhart, A; Loriferne, JF; Mosbah, A; Paugam, C; Perier, JF; Said, R; Weickmans, H, 2005) |
| "Propacetamol was not significantly different from ketorolac 15 mg and 30 mg with respect to the main analgesic efficacy variables during the 6-h assessment period." | 6.70 | Propacetamol versus ketorolac for treatment of acute postoperative pain after total hip or knee replacement. ( Tang, J; White, PF; Zhou, TJ, 2001) |
| "The acetaminophen group had lower pain scores on Day 1 (2." | 6.69 | Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain. ( Fox, L; McGuinnety, M; Schug, SA; Sidebotham, DA; Thomas, J, 1998) |
| "Acetaminophen does not inhibit this synthesis at the inflammatory site." | 6.55 | Pharmacology of Acetaminophen, Nonsteroidal Antiinflammatory Drugs, and Steroid Medications: Implications for Anesthesia or Unique Associated Risks. ( Candido, KD; Knezevic, NN; Perozo, OJ, 2017) |
| "This could be shown for dental but not postsurgical pain, because more patients were available for the former." | 6.41 | Combination analgesic efficacy: individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain. ( Edwards, JE; McQuay, HJ; Moore, RA, 2002) |
| "Forty-five patients with rhegmatogenous retinal detachments undergoing SB or SB and pars plana vitrectomy were randomly assigned to either standard care of postoperative oral acetaminophen and oxycodone/acetaminophen as needed or standard care plus 8 mg single-dose peri-operative intravenous dexamethasone." | 5.69 | Efficacy of Perioperative Intravenous Dexamethasone on Postoperative Analgesia in Scleral Buckle Surgery: A Randomized Clinical Trial. ( Fine, HF; Hassan, OT; Henderson, MN; Mantopoulos, D; Prenner, JL; Wheatley, EI, 2023) |
| "Among patients with cancer pain on strong opioid regime, acetaminophen may not improve pain control, or decrease total opioid use." | 5.69 | Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial. ( Castellano, J; González, A; Leiva-Vásquez, O; Letelier, LM; Pérez-Cruz, PE; Rojas, L; Viviani, P, 2023) |
| "As compared with placebo, VX-548 at the highest dose, but not at lower doses, reduced acute pain over a period of 48 hours after abdominoplasty or bunionectomy." | 5.69 | Selective Inhibition of Na ( Beaton, A; Bertoch, T; Bozic, C; Buvanendran, A; Correll, DJ; Habib, AS; Hare, B; Jazic, I; Jones, J; Lechner, SM; Miao, X; Negulescu, P; Osteen, JD; Pizzi, LJ; Pollak, RA; Shaw, D; Simard, C; Weiner, SG; White, PF, 2023) |
| " We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS." | 5.56 | Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020) |
| "Both ESB and PVB were effective in controlling acute pain and persistent herpetic pain after 6 months (which was evident by lower NRS for pain and doses of pregabalin and acetaminophen), but ESB is safer (no reported pneumothorax and hypotension)." | 5.51 | Ultrasound-Guided Erector Spinae Block Versus Ultrasound-Guided Thoracic Paravertebral Block for Pain Relief in Patients With Acute Thoracic Herpes Zoster: A Randomized Controlled Trial. ( Abdelwahab, EH; Afandy, ME; Fattooh, NH; Hodeib, AA; Marof, HM, 2022) |
| "Time to flatus was decreased by 1." | 5.48 | Liposomal bupivacaine reduces narcotic use and time to flatus in a retrospective cohort of patients who underwent laparotomy. ( Bamboat, ZM; Burnett, A; Faley, B; Nyirenda, T, 2018) |
| " We are uncertain whether tramadol reduces mortality compared to placebo; none of the studies reported pain scores, major neurodevelopmental disability, cognitive and educational outcomes in children older than five years old, retinopathy of prematurity, or intraventricular hemorrhage." | 5.41 | Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates. ( Borges do Nascimento, IJ; Bruschettini, M; Kinoshita, M; Stempel, KS, 2023) |
| "This study aims to evaluate the efficacy and safety of multiple or single-dosage intravenous ibuprofen (IVIB) in managing postoperative pain and fever in adults who are unable to take oral medications." | 5.41 | Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta-analysis of randomized controlled trials. ( Chen, L; He, L; Tian, S; Wang, E; Zhai, S; Zhou, P, 2023) |
| "The study aimed to compare the acetaminophen administration efficacy or its combination with codeine for pain control in acute apical abscesses cases." | 5.41 | Comparison between isolated and associated with codeine acetaminophen in pain control of acute apical abscess: a randomized clinical trial. ( Cardoso, MBF; da Rosa, RA; da Silva, PB; do Nascimento, AL; Mendes, AT; Pereira, JR; Só, MVR, 2021) |
| "Delirium is a side effect associated with narcotic analgesics, with a higher incidence in the elderly." | 5.37 | Oxycodone induced delirium and agitation in an elderly patient following total right knee arthroplasty. ( Crane, JH; Suda, KJ, 2011) |
| " Eligible patients (male and female subjects, aged 18-65 years, reporting pain intensity levels ≥40 mm on a 100-mm visual analog scale (VAS) after distal, first metatarsal bunionectomy) were randomized (3:3:3:2) to receive the FDC (ibuprofen 300 mg + acetaminophen 1000 mg), ibuprofen 300 mg, acetaminophen 1000 mg, or placebo (vehicle), administered as 15-minute intravenous infusions every 6 hours for 48 hours." | 5.30 | Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial. ( Atkinson, HC; Daniels, SE; Gottlieb, IJ; Playne, R; Stanescu, I; Zhang, J, 2019) |
| " With evidence suggesting that intravenous acetaminophen (IVA) can be an opioid sparing option, we conducted a prospective, randomized trial that evaluated the effect of IVA on the postoperative pain course of children with perforated appendicitis." | 5.30 | Does Intravenous Acetaminophen Improve Postoperative Pain Control after Laparoscopic Appendectomy for Perforated Appendicitis? A Prospective Randomized Trial. ( Desai, AA; Doyle, NM; Fraser, JD; Gonzalez, KW; Millspaugh, DL; Poola, AS; Sola, R; St Peter, SD; Weaver, KL, 2019) |
| "To evaluate the prevention of opioid-induced nausea and vomiting (OINV) and the relief of moderate to severe acute pain by CL-108, a novel drug combining a low-dose antiemetic (rapid-release promethazine 12." | 5.30 | Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi ( Chou, JC; Daniels, SE; Giannakopoulos, HE; Granquist, EJ; Levin, LM; Maibach, H; Muse, DD; Oreadi, D; Papas, AS; Patrick, K; Schachtel, BP; Zuniga, JR, 2019) |
| "To compare the effect of preoperative intravenous (IV) acetaminophen compared with placebo on pain scores after pelvic organ prolapse surgery." | 5.30 | Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial. ( Shepherd, JP; Turner, LC; Zyczynski, HM, 2019) |
| " The rate of ileus was reduced by using IV acetaminophen (22% vs 2." | 5.27 | Decreased opioid consumption and enhance recovery with the addition of IV Acetaminophen in colorectal patients: a prospective, multi-institutional, randomized, double-blinded, placebo-controlled study (DOCIVA study). ( Aryaie, AH; Juergens, C; Lalezari, S; Ogg, C; Puckett, Y; Ratermann, C; Sergent, WK, 2018) |
| "Anesthesia, acetaminophen, Persistent surgical pain, Postoperative acute pain." | 5.27 | Acetaminophen reduces acute and persistent incisional pain after hysterectomy. ( Akkurt, C; Hakimoglu, S; Koyuncu, O; Sessler, D; Turan, A; Turhanoglu, S; Ugur, M, 2018) |
| "Compared to women who received paracetamol, women who received lornoxicam after dilation and curettage for termination of pregnancy reported lower levels of pain, from 30 minutes postoperative until the time of discharge following the procedure." | 5.24 | Comparison between Lornoxicam and Paracetamol for Pain Management after Dilation and Curettage for Abortion. ( Abecassis, P; Assaraf, S; Dabaja, H; Hadad, S; Jarrous, S; Lowenstein, L; Mustafa-Mikhail, S, 2017) |
| "We evaluated the efficacy of oral administration of a mixture of diosmin, coumarin glycosides, and Centella asiatica (Venoplant®) in preventing bleeding, pain, and thrombosis of internal and external hemorrhoids after stapled anopexy (SA)." | 5.24 | Effect of a mixture of diosmin, coumarin glycosides, and triterpenes on bleeding, thrombosis, and pain after stapled anopexy: a prospective, randomized, placebo-controlled clinical trial. ( Cipolat Mis, T; Del Giudice, R; Nicolì, F; Schiano di Visconte, M, 2017) |
| "The aim of this study was to evaluate the effects of a preoperative popliteal block on sevoflurane consumption, postoperative pain, and analgesic consumption in children with cerebral palsy (CP) following lower limb surgery." | 5.24 | Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial). ( Akkaya, T; Bakir, M; Gonen, E; Ozkan, D, 2017) |
| " All studies analysed support that toxicity is not reached; and that acetaminophen provides a morphine sparing effect without adverse effects." | 5.22 | The efficacy and safety of acetaminophen use following liver resection: a systematic review. ( Koea, J; Murphy, V; Srinivasa, S, 2022) |
| "Buprenorphine formulations (including buprenorphine/naloxone) are effective treatments of pain and opioid use disorder (OUD)." | 5.22 | Perioperative Buprenorphine Management: A Multidisciplinary Approach. ( Abelleira, A; Acampora, G; Becker, WC; Falker, CG; Hickey, T; Nazario, M; Weimer, MB, 2022) |
| "The combination of ibuprofen/paracetamol, taken immediately after initial endodontic therapy and root canal preparation in teeth with irreversible pulpitis, reduced post-endodontic pain (ClinicalTrials." | 5.22 | Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain. ( Abubakr, NH; Elzaki, WM; Ibrahim, YE; Ziada, HM, 2016) |
| "A total of 120 children, who were candidate for elective surgical repair of unilateral inguinal hernia, were enrolled and randomly allocated to four groups of 30 patients each to receive IV acetaminophen, acetaminophen suppository, IV placebo, and placebo suppository during surgery." | 5.22 | COMPARISON OF THE EFFECTS OF PREEMPTIVE INTRAVENOUS AND RECTAL ACETAMINOPHEN ON PAIN MANAGEMENT AFTER INGUINAL HERNIORRHAPHY IN CHILDREN: A PLACEBO-CONTROLLED STUDY. ( Khalili, GR; Shafa, A; Yousefi, R, 2016) |
| "A fixed-dose combination biphasic immediate-release (IR)/extended-release (ER) hydrocodone bitartrate (HB)/acetaminophen (APAP) tablet is being developed for the management of acute pain severe enough to require opioid treatment and for which alternative treatment options are inadequate." | 5.20 | Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen tablets for acute postoperative pain. ( Barrett, T; Chen, Y; Giuliani, MJ; Kostenbader, K; Margulis, R; Singla, N; Young, JL; Zheng, Y, 2015) |
| "To assess opioid-sparing effects of oral or intravenous acetaminophen following primary cleft palate repair in children." | 5.19 | Analgesic effectiveness of acetaminophen for primary cleft palate repair in young children: a randomized placebo controlled trial. ( Applegate, RL; Hassanian, M; Martin, M; Mason, L; Nour, C; Ratsiu, J; Ray, A; Singh, N; Uhler, J, 2014) |
| "The aim of the present study was to investigate the analgesic and anti-inflammatory effects of dexketoprofen trometamol (DT) and paracetamol on deep acute somatic pain and inflammation in patients undergoing impacted third molar surgery." | 5.19 | Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study. ( Durmus, E; Eroglu, CN; Kiresi, D, 2014) |
| "To investigate the safety and satisfaction of patients treated ≤ 14 days after unilateral bunionectomy with extended-release oxycodone/acetaminophen (ER OC/APAP), a biphasic (ER and immediate release) fixed-dose combination analgesic being developed for moderate to severe acute pain." | 5.19 | Assessment of the safety and efficacy of extended-release oxycodone/acetaminophen, for 14 days postsurgery. ( Barrett, T; Kostenbader, K; Singla, N; Sisk, L; Young, J, 2014) |
| " In this double-blind clinical trial, 100 patients who had anterior or premolar teeth with irreversible pulpitis without any signs and symptoms of acute or chronic apical periodontitis and moderate to severe pain were divided by balanced block random allocation into four groups of 25 each, a control group receiving a placebo medication, and three experimental groups receiving a single dose of either Tramadol (100 mg), Novafen (325 mg of paracetamol, 200 mg ibuprofen and 40 mg caffeine anhydrous) or Naproxen (500 mg) immediately after the first appointment where the pulp was removed, and the canals were fully prepared." | 5.16 | Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial. ( Abbott, PV; Asgar, K; Delvarani, A; Karamifar, K; Khabazi, H; Kharazifard, MJ; Lotfi, M; Mehrvarzfar, P; Saghiri, MA, 2012) |
| "We sought to compare the efficacy and safety profiles of aspirin, acetaminophen with codeine, and placebo in the treatment of post-operative dental pain and tension-type headache." | 5.16 | Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension-type headache and postoperative dental pain. ( Fisher, M; Gatoulis, SC; Voelker, M, 2012) |
| "A randomized, placebo-controlled, double-blind study to evaluate the effect of intravenously (IV) administered acetaminophen on postoperative pain in children and adolescents undergoing surgery for idiopathic scoliosis or spondylolisthesis." | 5.16 | Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents. ( Hartikainen, T; Helenius, I; Hiller, A; Kaukonen, M; Korpela, R; Meretoja, OA; Neuvonen, PJ; Nurmi, E; Taivainen, T, 2012) |
| "Pregabalin in the doses given decreased morphine requirements for the first 48 h postoperatively, but neither altered the analgesic requirements beyond 48 h nor had any effect on acute, late or chronic pain." | 5.16 | Perioperative pregabalin for acute and chronic pain after abdominal hysterectomy or myomectomy: a randomised controlled trial. ( Fassoulaki, A; Melemeni, A; Paraskeva, A; Tsaroucha, A, 2012) |
| "This double-blind, randomized controlled study evaluated etoricoxib (90 and 120 mg), ibuprofen (600 mg), and acetaminophen (600 mg/codeine) (60 mg, (A/C)) in patients aged ≥ 18 years with moderate or severe pain after surgical extraction of ≥ 2 third molars (≥ 1 impacted)." | 5.15 | Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model. ( Bandy, DP; Boice, J; Christensen, SE; Daniels, SE; Liu, H; Losada, MC; Mehta, A; Peloso, PM, 2011) |
| "Investigators from Bristol described a fentanyl- and diclofenac-based analgesic technique for tonsillectomy with low postoperative nausea and vomiting rates and low pain scores." | 5.15 | A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy*. ( Bagshaw, O; Rawlinson, E; Skone, R; Thillaivasan, A; Walker, A, 2011) |
| "To assess clinical equivalence of 20 mg controlled-release oxycodone (Oxygesic; Mundipharma, Limburg, Germany) and 200 mg controlled-release tramadol (Tramal long; Grunenthal, Aachen, Germany) on a 12-hour dosing schedule in a randomized, double-blinded study of 54 ASA I-III physical status (American Society of Anesthesiologists classification of physical status) patients undergoing surgery for breast cancer." | 5.14 | Clinical equivalence of controlled-release oxycodone 20 mg and controlled-release tramadol 200 mg after surgery for breast cancer. ( Dagtekin, O; Kampe, S; Landwehr, S; Shaheen, S; Warm, M; Wolter, K, 2009) |
| " We hypothesized that dexamethasone would reduce the need for oxycodone after surgical correction of hallux valgus." | 5.14 | Dexamethasone decreases oxycodone consumption following osteotomy of the first metatarsal bone: a randomized controlled trial in day surgery. ( Hynynen, MJ; Kalso, E; Kontinen, VK; Mattila, K, 2010) |
| "In this prospective, randomized, double-blinded study we sought to evaluate the efficacy and safety of combined use of intravenous ketorolac and acetaminophen in small children undergoing outpatient inguinal hernia repair." | 5.14 | Fentanyl sparing effects of combined ketorolac and acetaminophen for outpatient inguinal hernia repair in children. ( Hong, JY; Kil, HK; Kim, WO; Won Han, S, 2010) |
| "This study compared the effect of single-dose caudal epidural bupivacaine, bupivacaine plus ketamine and bupivacaine plus tramadol for postoperative pain management in children having surgery for inguinal hernia." | 5.13 | Comparison of caudal epidural bupivacaine with bupivacaine plus tramadol and bupivacaine plus ketamine for postoperative analgesia in children. ( Choudhuri, AH; Dharmani, P; Kumarl, N; Prakash, A, 2008) |
| "To assess clinical efficacy of IV paracetamol 1 g and IV dipyrone 1 g on a 24-h dosing schedule in this randomised, double-blinded study of 40 ASA I-III (American Society of Anesthesiologists classification of physical status) patients undergoing surgery for breast cancer." | 5.12 | Clinical equivalence of IV paracetamol compared to IV dipyrone for postoperative analgesia after surgery for breast cancer. ( Dagtekin, O; Haussmann, S; Kampe, S; Kiencke, P; Landwehr, S; Paul, M; Pilgram, B; Warm, M, 2006) |
| "A prospective, randomised, double-blind, clinical evaluation was performed to compare the efficacy of a single bolus injection of 40 mg parecoxib and 2 g propacetamol, administered twice within 12 h following surgical repair of inguinal hernia." | 5.12 | Cost analysis applied to postoperative analgesia regimens: a comparison between parecoxib and propacetamol. ( Beaussier, M; Lienhart, A; Sean, PT; Tilleul, P; Weickmans, H, 2007) |
| "Peroral oxycodone is effective for early pain control after fast-track cardiac anesthesia." | 5.12 | Early oral analgesia after fast-track cardiac anesthesia. ( Eidelman, LA; Kogan, A; Medalion, B; Pak, N; Raanani, E; Sharoni, E; Stamler, A; Vidne, BA, 2007) |
| "Our aim was to show the efficacy of naproxen and paracetamol with and without pethidine on pain and nausea and vomiting after adenoidectomy." | 5.12 | Oral naproxen but not oral paracetamol reduces the need for rescue analgesic after adenoidectomy in children. ( Korpela, R; Laakso, E; Meretoja, OA; Silvola, J, 2007) |
| "The aim of the study is to evaluate the efficacy of post-incisional wound infiltration with levobupivacaine in preventing the postoperative pain associated with inguinal hernia repair in children." | 5.12 | Wound infiltration with levobupivacaine: an alternative method of postoperative pain relief after inguinal hernia repair in children. ( Kostopanagiotou, G; Matsota, P; Papageorgiou-Brousta, M, 2007) |
| "Dexmedetomidine provides a modest analgesic effect after knee arthroscopy, but the side effects of this drug, such as hypertension and bradycardia, may restrict the use of large bolus doses." | 5.12 | Clinical analgesic efficacy and side effects of dexmedetomidine in the early postoperative period after arthroscopic knee surgery. ( Gómez-Vázquez, ME; Hernández-Jiménez, A; Hernández-Salazar, E; Pérez-Sánchez, A; Salazar-Páramo, M; Zepeda-López, VA, 2007) |
| ") formulation of paracetamol and propacetamol (prodrug of paracetamol) were compared to determine tolerance and relative analgesic efficacy during the first 6 h after inguinal hernia repair performed under general anesthesia combined with ilioinguinal block in children." | 5.11 | Tolerance and analgesic efficacy of a new i.v. paracetamol solution in children after inguinal hernia repair. ( Baujard, C; Foussat, C; Guyot, E; Murat, I; Petel, H; Ricard, C; Rod, B, 2005) |
| "Acetaminophen decreases post-thoracotomy ipsilateral shoulder pain when given preemptively and regularly during the first 48 hours postoperatively in patients who received thoracic epidural analgesia." | 5.11 | Acetaminophen decreases early post-thoracotomy ipsilateral shoulder pain in patients with thoracic epidural analgesia: a double-blind placebo-controlled study. ( Boudreault, D; Chouinard, P; Ferraro, P; Girard, F; Lafontaine, ER; Mac, TB; Ruel, M, 2005) |
| "Intravesical morphine was recently recommended to reduce postoperative pain after reimplantation surgery for vesicoureteral reflux in children." | 5.10 | Intravesical morphine analgesia is not effective after bladder surgery in children: results of a randomied double-blind study. ( Aigrain, Y; Deffarges, C; El-Ghoneimi, A; Hankard, R; Jacqz-Aigrain, E; Jean-Eudes, F, 2002) |
| "Caudal neostigmine 2 micro g/kg provides postoperative analgesia comparable to caudal bupivacaine in children undergoing hypospadias repair surgery." | 5.10 | Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children. ( Abdulatif, M; El-Sanabary, M, 2002) |
| "The objectives of this study were to compare the incidence, onset, duration and pain scores of transient neurologic symptoms (TNS) with 1% versus 5% hyperbaric lidocaine in spinal anesthesia for short urological procedures in a large prospective study." | 5.10 | Prospective study on incidence and functional impact of transient neurologic symptoms associated with 1% versus 5% hyperbaric lidocaine in short urologic procedures. ( Bremang, J; Chung, F; Friedlander, M; Mezei, G; Streiner, D; Tong, D; Wong, J, 2003) |
| "In the sub-Tenon's bupivacaine group, there was a significant reduction in the perioperative opioid use and a reduction in the frequency of bradycardia and hypertensive episodes, defined as a rise > 25% of baseline for a duration of > 3 min." | 5.10 | Sub-Tenon's block reduces both intraoperative and postoperative analgesia requirement in vitreo-retinal surgery under general anaesthesia. ( Farmery, AD; Rahman, R; Rosen, P; Shlugman, D, 2003) |
| "To determine the efficacy of oral granisetron in preventing postoperative vomiting (POV) following strabismus repair in children." | 5.09 | Oral granisetron for strabismus surgery in children. ( D'Errico, CC; Lauder, GR; Munro, HM; Tait, AR; Voepel-Lewis, T; Wagner, DS, 1999) |
| "This randomized, double-blind, placebo-controlled study compared the time to onset of analgesia and the analgesic efficacy of two formulations of acetaminophen 1000 mg--an effervescent solution and tablet--in 242 patients with moderate or severe pain following dental surgery." | 5.09 | Time to onset of analgesia and analgesic efficacy of effervescent acetaminophen 1000 mg compared to tablet acetaminophen 1000 mg in postoperative dental pain: a single-dose, double-blind, randomized, placebo-controlled study. ( Ganry, HE; Insuasty, JH; Møller, PL; Nørholt, SE; Sindet-Pedersen, S; Skoglund, LA; Vincent, FG, 2000) |
| "Rectal acetaminophen (Ac) is often administered prophylactically at anesthesia induction for postoperative pain management in small children and is thought to have an opioid-sparing effect." | 5.09 | Prophylactically-administered rectal acetaminophen does not reduce postoperative opioid requirements in infants and small children undergoing elective cleft palate repair. ( Behne, M; Bremerich, DH; Heimann, K; Kessler, P; Neidhart, G, 2001) |
| "High dose acetaminophen (100 mg/kg) was no more effective than 40 mg/kg and was associated with increased nausea and vomiting." | 5.09 | Acetaminophen analgesia in children: placebo effect and pain resolution after tonsillectomy. ( Anderson, BJ; Holford, NH; Woollard, GA, 2001) |
| " Pain at rest, during cough, and mobilization, request for supplementary morphine, and time to first postoperative flatus, was reduced in patients receiving 24-h postoperative epidural anaesthesia, compared with the two other groups." | 5.09 | Effect of peri- and postoperative epidural anaesthesia on pain and gastrointestinal function after abdominal hysterectomy. ( Andreasson, B; Dahl, JB; Dirks, J; Fomsgaard, JS; Jørgensen, H; Wetterslev, J, 2001) |
| " This study has attempted to assess postoperative analgesic consumption and nausea and vomiting after general anaesthesia for tonsillectomy using either paracetamol premedication, paracetamol plus a NSAID or intravenous morphine to provide postoperative analgesia." | 5.08 | Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques. ( Mather, SJ; Peutrell, JM, 1995) |
| "Fifty-four ASA I and II children 1 to 10 yr of age undergoing strabismus surgery were randomized to receive in a double-blind fashion intravenous ketorolac (0." | 5.08 | The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery. ( Guarnieri, KM; Mendel, HG; Sundt, LM; Torjman, MC, 1995) |
| "A prospective, comparative, randomized study to assess rectal acetaminophen (n = 45) to intravenous fentanyl-droperidol (n = 45) to resolve recovery profile, emesis rate, and adequacy of analgesia in a pediatric strabismus repair population was performed, with standardization of the anesthetic technique." | 5.08 | Comparison of postoperative emesis, recovery profile, and analgesia in pediatric strabismus repair. Rectal acetaminophen versus intravenous fentanyl-droperidol. ( Cruz, OA; Krock, JL; Padda, GS, 1997) |
| "The efficacy and tolerability of nimesulide were assessed and compared with those of paracetamol in the treatment of 35 children with pain and inflammation following adenotonsillectomy." | 5.07 | An assessment of the efficacy and tolerability of nimesulide vs paracetamol in children after adenotonsillectomy. ( D'Agostino, R; Pasquale, G; Scaricabarozzi, I; Taborelli, G; Vallarino, R, 1993) |
| "Recognizing the concerns about the use of local anesthesia in neonatal circumcision, a painful procedure usually performed without analgesia or anesthesia, we undertook a study of acetaminophen for pain management of this procedure." | 5.07 | Acetaminophen analgesia in neonatal circumcision: the effect on pain. ( Howard, CR; Howard, FM; Weitzman, ML, 1994) |
| " The authors compare the effectiveness of a single intravenous dose of ketorolac with a single oral dose of either acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus." | 5.07 | Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus. ( Morrison, NA; Repka, MX, 1994) |
| "At Helsinki University Central Hospital in Finland, clinical researchers divided 169 women into two groups (group 1: diagnostic laparoscopies; group 2: laparoscopic sterilizations) as part of a study to evaluate the effect of intravenous diclofenac on postoperative pain, nausea, and recovery after outpatient gynecological laparoscopy." | 5.07 | Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy. ( Hovorka, J; Kallela, H; Korttila, K, 1993) |
| "Diclofenac sodium suppositories 150-200 mg day-1 were compared with placebo in a double-blind study during the first 3 days after uvulopalatopharyngoplasty in 40 patients with habitual snoring or obstructive sleep apnoea syndrome." | 5.07 | Treatment of postoperative pain with diclofenac in uvulopalatopharyngoplasty. ( Björkman, R; Ejnell, H; Hedner, J; Wåhlander, L, 1992) |
| "We compared naproxen sodium (550 mg) and propoxyphene napsylate with acetaminophen (PN/A, 100 mg with 650 mg) for pain relief after arthroscopy or arthroscopic meniscectomy." | 5.06 | Pain relief after arthroscopy: naproxen sodium compared to propoxyphene napsylate with acetaminophen. ( Drez, D; Ritter, M; Rosenberg, TD, 1987) |
| " The second study compared three weeks of treatment with daily doses of 200 mg of flurbiprofen and 4 g of acetaminophen in 50 patients with acute low back pain." | 5.06 | Flurbiprofen for the treatment of soft tissue trauma. ( Muckle, DS, 1986) |
| " Ketamine was shown to increased postoperative nausea and vomiting." | 5.05 | Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review. ( Lin, H; Nguyen, BK; Pashkova, AA; Pinto, J; Quan, D; Stathakios, J; Svider, PF, 2020) |
| "The anxiety and pain-relieving effect of paracetamol 10 mg/kg or a combination of aminophenazone 4 mg/kg and diazepam 0." | 5.05 | Comparison of paracetamol and aminophenazone plus diazepam suppositories for anxiety and pain relief after tonsillectomy in children. ( Lindgren, L; Saarnivaara, L, 1985) |
| "A double-blind, cross-over trial was made of three analgesic preparations--paracetamol, paracetamol with caffeine (Finimal) and aspirin in the relief of postoperative pain in 72 orthopedic inpatients and in 144 ambulatory outpatients suffering form common idiopathic headache." | 5.04 | A double-blind comparative evaluation of aspirin, paracetamol and paracetamol + caffeine (finimal) for their analgesic effectiveness. ( Lawczyński, L; Olszewska, M; Samochowiec, L; Szwed, G; Wójcicki, J, 1977) |
| " Paracetamol (acetaminophen) is the most commonly prescribed analgesic for the treatment of acute pain." | 4.93 | Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain. ( Carr, DB; Ferguson, MC; Haroutounian, S; McNicol, ED; Schumann, R, 2016) |
| " The earlier review included 20 studies (7238 participants) in valid comparisons, but because we used different outcomes for some headache studies, the number of participants in the analyses of the effects of caffeine is now 4262 when previously it was 5243." | 4.90 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2014) |
| " Most studies used paracetamol or ibuprofen, with 100 mg to 130 mg caffeine, and the most common pain conditions studied were postoperative dental pain, postpartum pain, and headache." | 4.88 | Caffeine as an analgesic adjuvant for acute pain in adults. ( Derry, CJ; Derry, S; Moore, RA, 2012) |
| "The inclusion criteria used were: full journal publication, postoperative pain, postoperative oral administration, adult patients, baseline pain of moderate to severe intensity, double-blind design, and random allocation to treatment groups which included dextropropoxyphene and placebo or a combination of dextropropoxyphene plus paracetamol and placebo." | 4.80 | Single dose dextropropoxyphene, alone and with paracetamol (acetaminophen), for postoperative pain. ( Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA, 2000) |
| "Inclusion criteria were: full journal publication, postoperative pain, postoperative oral administration, adult patients, baseline pain of moderate to severe intensity, double-blind design, and random allocation to treatment groups which compared paracetamol with placebo or a combination of paracetamol and codeine with either placebo or the same dose of paracetamol alone." | 4.80 | Single dose paracetamol (acetaminophen), with and without codeine, for postoperative pain. ( Carroll, D; Collins, S; Edwards, J; McQuay, H; Moore, A, 2000) |
| "The inclusion criteria were: full journal publication, clinical trial, random allocation of adult patients to treatment groups, double blind design, moderate to severe baseline pain, postoperative administration of study drugs, treatment arms which included oxycodone or oxycodone plus paracetamol and placebo (or active control for which comparable efficacy data exist), and oral, intramuscular or intravenous administration of study drugs." | 4.80 | Single dose oxycodone and oxycodone plus paracetamol (acetominophen) for acute postoperative pain. ( Edwards, JE; McQuay, HJ; Moore, RA, 2000) |
| "In order to assess the analgesia obtained from single oral doses of paracetamol alone and in combination with codeine in postoperative pain, we conducted a systematic review of randomised controlled trials." | 4.79 | Paracetamol with and without codeine in acute pain: a quantitative systematic review. ( Carroll, D; Collins, S; McQuay, H; Moore, A, 1997) |
| "The aim of this study was to determine whether the administration of liposomal bupivacaine decreased opioid use and delirium in patients sustaining a hip fracture." | 4.31 | Liposomal Bupivacaine Decreases Intravenous Opioid Use in Patients with Hip Fracture: A Modification to a Novel Pain Protocol. ( Donegan, D; Fryhofer, GW; Looby, S; Mehta, S; Stein, MK; Stevenson, KL, 2023) |
| "Opioid analgesia for acute painful conditions has come under increasing scrutiny with the public health crisis of opioid overdose, leading clinicians to seek nonopioid alternatives, such as nonsteroidal anti-inflammatory drugs (NSAIDs) and acetaminophen (paracetamol)." | 4.02 | Can NSAIDs and Acetaminophen Effectively Replace Opioid Treatment Options for Acute Pain? ( Breve, F; LeQuang, JA; Magnusson, P; Pergolizzi, JV; Taylor, R; Varrassi, G; Wollmuth, C, 2021) |
| "Regression analysis showed that severe spinal cord injury and peri-treatment use of acetaminophen dihydrocodeine were both one of the risk factors for postoperative chronic pain." | 4.02 | A retrospective analysis of the effects of different analgesics on the pain of patients with traumatic thoracolumbar fractures in the peri-treatment period. ( Chang, QY; Chen, J; Gan, ZJ; Li, TT; Wang, YT; Wen, S; Xiong, LL; Yuan, H, 2021) |
| "Scheduled intravenous acetaminophen administration is effective and feasible for the postoperative pain management of patients undergoing esophagectomy and may be associated with a lower incidence of anastomotic leakage and postoperative delirium." | 3.96 | Scheduled intravenous acetaminophen versus nonsteroidal anti-inflammatory drugs (NSAIDs) for better short-term outcomes after esophagectomy for esophageal cancer. ( Abe, T; Fukaya, M; Higaki, E; Hosoi, T; Ito, S; Kawakami, J; Komori, K; Nagino, M; Nakatochi, M; Shimizu, Y, 2020) |
| "The combinations of IV acetaminophen with either intramuscular pethidine or IV parecoxib are superior to IV acetaminophen monotherapy in achieving pain control in patients undergoing open inguinal hernia repair." | 3.96 | Postoperative Pain Scores After Open Inguinal Hernia Repair: Comparison of Three Postoperative Analgesic Regimens. ( Gatomati, F; Iliopoulos, F; Maroulis, I; Mulita, F; Parchas, N; Solou, K; Tchabashvili, L, 2020) |
| " Our anesthetic protocol for strabismus surgery included postoperative nausea and vomiting prevention using dexamethasone and ondansetron." | 3.91 | Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery. ( Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M, 2019) |
| " The protocol utilized oral celecoxib and scheduled oral acetaminophen for pain control, with opioids used only as needed for breakthrough pain." | 3.91 | Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass. ( Dove, J; Fluck, M; Gabrielsen, JD; Gionfriddo, MR; Horsley, RD; McField, DAP; Medico, C; Parker, DM; Petrick, AT; Vogels, ED, 2019) |
| "Scheduled intravenous acetaminophen after thoracoscopic esophagectomy in patients with esophageal cancer was a useful strategy in reducing the incidence of postoperative pneumonia." | 3.91 | Scheduled Intravenous Acetaminophen for Postoperative Management of Patients Who Had Thoracoscopic Esophagectomy for Esophageal Cancer. ( Hanazaki, K; Iwabu, J; Kitagawa, H; Kobayashi, M; Munekage, M; Namikawa, T; Tsuda, S; Uemura, S; Yokota, K, 2019) |
| " Patients were advised to use acetaminophen and ibuprofen, and were provided with a small "rescue" opioid prescription for breakthrough pain." | 3.91 | Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway. ( Brummett, C; Englesbe, M; Hallway, A; Howard, R; Lee, J; Palazzolo, W; Vu, J; Waljee, J, 2019) |
| "The goal of this prospective cohort study was to model cost-effectiveness of adding acetaminophen or acetaminophen + ketorolac to opioids for postoperative outcomes in children having scoliosis surgery." | 3.88 | Cost-effectiveness of intravenous acetaminophen and ketorolac in adolescents undergoing idiopathic scoliosis surgery. ( Chidambaran, V; Ding, L; Eckman, MH; Geisler, K; Jain, V; Sadhasivam, S; Stubbeman, B; Sturm, P; Subramanyam, R, 2018) |
| "The objective of this study was to determine: 1) the incidence and the risk factors of diclofenac/acetaminophen combination as a single agent induced Acute Kidney Injury (AKI) in postoperative pain relief 2) the average cost and length of hospital stay for patients in AKI group and non-AKI group." | 3.88 | Diclofenac--Acetaminophen Combination Induced Acute Kidney Injury In Postoperative Pain Relief. ( Banh, HL; Cave, A; Li, YY; Luo, JQ; Wang, Q; Xiao, YW; Xu, P; Zhou, YG; Zhu, Y, 2018) |
| "This study aimed to determine whether intraoperative acetaminophen was able to decrease opioid consumption, pain scores, and length of stay while increasing oral intake in cleft palate surgery." | 3.88 | Opioid Sparing in Cleft Palate Surgery. ( Brgoch, M; Carr, L; Gray, M; Mackay, D; Morrow, B; Samson, T, 2018) |
| "Trials in acute postoperative pain are usually small." | 3.80 | Meta-analysis of single dose oral tramadol plus acetaminophen in acute postoperative pain. ( Edwards, J; McQuay, H, 2003) |
| "A retrospective review of cleft palate cases over a 1-year period, 6 months with hemostatic pledgets, and 6 months with bupivacaine-soaked hemostatic pledgets." | 3.77 | Does use of bupivacaine-soaked pledgets aid in the care of postoperative cleft palate patients? ( Burstein, FD; Otterburn, DM, 2011) |
| "Presented are the results of four postsurgical pain studies, one study of acute gouty arthritis and nine studies of acute musculoskeletal disorders: acute low back pain, acute painful shoulder, tendinitis and bursitis, and acute sports injuries." | 3.76 | Etodolac: analgesic effects in musculoskeletal and postoperative pain. ( Pena, M, 1990) |
| "Despite the use of regional anesthesia, chronic opioid consumption before leg amputation is associated with increased postoperative morphine consumption and phantom limb pain." | 3.75 | Preoperative opioid consumption increases morphine requirement after leg amputation. ( Bénard, A; Bernard, N; Biais, M; Capdevila, X; Nouette-Gaulain, K; Revel, P; Roullet, S; Sztark, F, 2009) |
| " Switching to an opioid combined with acetaminophen or aspirin does not result in greater analgesia, but increases the incidence of side effects such as drowsiness and nausea." | 3.70 | Additive analgesia without opioid side effects. ( Dionne, R, 2000) |
| "Labor pain is one of the most agonizing pains experienced by all delivered women." | 3.30 | Comparison of intravenous paracetamol infusion versus intramuscular tramadol as labor analgesia: a randomized control trial. ( Monisha, N; Poomalar, GK, 2023) |
| " This open-label study (NCT03974932) evaluated the efficacy and safety of HTX-011 combined with an MMA regimen in patients undergoing TKA under spinal anesthesia." | 3.30 | HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study. ( Berkowitz, R; Hacker, S; Hu, J; Lee, GC; Rechter, A, 2023) |
| "Standardized postoperative pain medication including Ibuprofen, Acetaminophen, and narcotics were given as needed." | 3.30 | A randomized, placebo-controlled study of magnetic acupuncture for supplementary analgesia after laparoscopic appendectomy in children. ( Feng, H; König, J; König, T; Muensterer, O, 2023) |
| "The primary outcome measure was postoperative pain intensity on movement measured by an 11-point NRS (where 0 = no pain and 10 = worst pain imaginable) on POD 1." | 3.30 | Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial. ( Callebaut, I; Dreesen, I; Evers, S; Herbots, J; Lambrechts, M; Ory, JP; Stessel, B; Van de Velde, M; Vanderstappen, C; Vaninbroukx, M, 2023) |
| "Neostigmine was co-administered with caudal bupivacaine to shorten the onset and extend the duration of analgesia." | 3.30 | Ultrasound-guided Techniques for Perioperative Analgesia in Pediatric Lower Abdominal Surgeries: Quadratus Lumborum Block with Bupivacaine versus Caudal Bupivacaine and Neostigmine. ( Ashoor, TM; Esmat, IM; Hasseb, AM; Reyad, MK; Zain, EM, 2023) |
| "The acetaminophen group was administered celecoxib at 400 mg, pregabalin at 150 mg, and acetaminophen at 300 mg 2 h before TKA." | 3.30 | Efficacy of Adding Acetaminophen to Preemptive Multimodal Analgesia in Total Knee Arthroplasty: A Double-blinded Randomized Study. ( Kang, P; Ma, T; Wang, L; Wang, Q; Zhao, C, 2023) |
| "Test drugs provided a reduction in postoperative pain scores and lower use of rescue medication when compared to placebo." | 3.30 | Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial. ( Alvarenga-Brant, R; Costa, FO; Cota, LOM; Esteves-Lima, RP; Mattos-Pereira, GH, 2023) |
| " Appropriate dosing will be determined based on the participant's gestational age." | 3.30 | Intravenous acetaminophen for postoperative pain in the neonatal intensive care unit: A protocol for a pilot randomized controlled trial (IVA POP). ( Archer, VA; Braga, LH; Briatico, D; Farrokyhar, F; Samiee-Zafarghandy, S; Walton, JM, 2023) |
| "Postoperative pain was significantly less in the bupivacaine group at 240 and 360 min after the surgery." | 3.11 | Comparing the efficacy of peritonsillar injection of bupivacaine and intravenous acetaminophen on post-tonsillectomy pain in children. ( Ayatollahi, V; Hosseini, H; Meybodian, M; Shariatmadari, M; Vaziribozorg, S, 2022) |
| "Treatment with diclofenac sodium vs hydrocodone/APAP did not statistically impact pain scores at PODs 1, 2, 3, or 5." | 3.11 | Are nonsteroidal anti-inflammatory drugs effective enough for postoperative pain control after functional endoscopic sinus surgery and septoplasty? A randomized, controlled study. ( Citardi, MJ; Jiang, ZY; Luong, AU; Radabaugh, P; Saini, AT; Schmale, I; Starr, NC; Talmadge, J; Yao, WC, 2022) |
| "Postoperative pain was reduced at 24 hours with one dose, and at 48 hours with two doses, of dexamethasone." | 3.11 | Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial. ( Ammitzboell, M; Bagger, J; Brorson, S; Gasbjerg, KS; Hägi-Pedersen, D; Holmqvist, M; Jakobsen, JC; Jakobsen, K; Jensen, MS; Laursen, CC; Lindberg-Larsen, M; Lindholm, P; Lunn, TH; Mathiesen, O; Nørskov, AK; Overgaard, S; Pallesen, MJ; Pedersen, NA; Schrøder, HM; Thybo, KH; Vinstrup, LØ, 2022) |
| "The primary outcome was postoperative pain-free period in minutes since deflation of proximal tourniquet." | 3.11 | Lidocaine Plus Morphine Versus Lidocaine Plus Paracetamol for Bier Block: A Double-Blind Randomized Controlled Trial. ( Afsahi, M; Hazrati, E; Karbalaeikhani, A; Kheradmand, B; Rafiei, M, 2022) |
| "IV tramadol infusion was administered with a Patient Controlled Analgesia device for postoperative analgesia." | 3.11 | Efficacy of Intravenous Ibuprofen and Intravenous Paracetamol in Multimodal Pain Management of Postoperative Pain After Percutaneous Nephrolithotomy. ( Aydogan, MS; Colak, YZ; Erdogan, MA; Ozgul, U; Sanlı, M; Ucar, M; Yucel, A, 2022) |
| "Further, counseling patients on postoperative pain before surgery can reduce the total number of postoperative narcotic and non-narcotic medications taken." | 3.11 | A prospective randomized study evaluating the necessity of narcotics following ureteroscopy for urinary stone disease. ( Atallah, W; Bamberger, JN; Chandhoke, RA; Gallante, B; Gupta, M; Khusid, JA; Sadiq, A; Shimonov, R; Yaghoubian, A; Zampini, AM, 2022) |
| "Postoperative pain was assessed using a visual analog scale (VAS) during postoperative 24 h." | 3.11 | Posterior quadratus lumborum block versus posterior transversus abdominis plane block for unilateral inguinal hernia surgery. ( Akelma, FK; Altinsoy, S; Caparlar, CO; Ergil, J; Ozhan, MO, 2022) |
| "Morphine (0." | 3.11 | Nociception Level Index-Directed Erector Spinae Plane Block in Open Heart Surgery: A Randomized Controlled Clinical Trial. ( Balan, C; Bubenek-Turconi, SI; Coman, A; Morosanu, B; Stanculea, I; Stoian, A; Tomescu, DR; Valeanu, L, 2022) |
| " Paracetamol has a very flat analgesic dose-response profile." | 3.01 | Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study. ( Lyngstad, G; Skjelbred, P; Skoglund, LA; Swanson, DM, 2021) |
| "Efficacy and rapid onset of postsurgical oral pain relief are critical to improve clinical outcomes and reduce the risk of excessive dosing with analgesic drugs." | 3.01 | COMPARATIVE ANALGESIC EFFECTS OF SINGLE-DOSE PREOPERATIVE ADMINISTRATION OF PARACETAMOL (ACETAMINOPHEN) 500 mg PLUS CODEINE 30 mg AND IBUPROFEN 400 mg ON PAIN AFTER THIRD MOLAR SURGERY. ( Annibali, S; Cristalli, MP; La Monaca, G; Polimeni, A; Pompa, G; Pranno, N; Vozza, I, 2021) |
| "To optimize postoperative pain control and minimize opioid requirements, interventions must occur at the preoperative, intraoperative, and postoperative time points." | 3.01 | Opioid-Sparing Pain Control after Rhinoplasty: Updated Review of the Literature. ( Lee, LN; Liu, RH; Xu, LJ, 2023) |
| "The procedure-specific postoperative pain management (PROSPECT) working group develops evidence-based pain management recommendations." | 3.01 | PROSPECT methodology for developing procedure-specific pain management recommendations: an update. ( Albrecht, E; Joshi, GP; Kehlet, H; Lobo, DN; Van de Velde, M, 2023) |
| "Acetaminophen pretreatment did not add analgesia any more than that of placebo." | 3.01 | Can Acetaminophen Pretreatment Decrease the Pain Associated With Closed Nasal Bone Reduction? A Triple-Blind Randomized Clinical Trial. ( Aghazadeh, K; Firouzifar, M; Mousavi-Asl, B; Safaeyan, M; Sohrabpour, S, 2021) |
| "Effective postoperative pain management after lumbar disc surgery reduces complications and improves postoperative care." | 3.01 | Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial. ( Akbas, S; Durak, MA; Ozkan, AS; Yologlu, S, 2021) |
| "Ibuprofen is an effective analgesic for postoperative pain relief in children undergoing primary tooth extraction." | 3.01 | Comparison of preemptive ibuprofen, acetaminophen, and placebo administration in reducing peri- and postoperative pain in primary tooth extraction: A randomized clinical trial. ( Raslan, N; Zouzou, T, 2021) |
| " Pain at rest/motion (based on pain visual analog scale (VAS) score), rescue analgesia consumption, satisfaction level and adverse events were assessed after AKS." | 3.01 | Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery. ( Di, J; Liu, J; Xing, E; Zhang, Y, 2021) |
| " Adverse event data was collected throughout the study, in addition to scheduled vital sign assessments, laboratory tests and electrocardiograms." | 3.01 | Extending the safety profile of the post-operative administration of an intravenous acetaminophen/ibuprofen fixed dose combination: An open-label, multi-center, single arm, multiple dose study. ( Atkinson, H; Carson, S; Gilchrist, N; Gottlieb, IJ; Stanescu, I, 2021) |
| "Acetaminophen is a frequently used adjunct analgesic in pediatric patients undergoing tonsillectomy and adenoidectomy." | 3.01 | Comparison of Oral Loading Dose to Intravenous Acetaminophen in Children for Analgesia After Tonsillectomy and Adenoidectomy: A Randomized Clinical Trial. ( Aizenberg, DA; Applegate, RL; Funamura, JL; Hall, B; Kriss, RS; Lammers, CR; Nittur, V; Schwinghammer, AJ; Senders, CW, 2021) |
| "PONV was assessed in recovery and 24 hours after surgery in the ward." | 3.01 | Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. ( Aghabagheri, M; Khajavi, MR; Najjari, K; Pourfakhr, P; Talebpour, M; Zabihi Mahmoudabadi, H, 2021) |
| "A more extensive postoperative pain regimen than paracetamol, ibuprofen and opioids may be needed for a large proportion of patients having total hip arthroplasty." | 3.01 | Participants with mild, moderate, or severe pain following total hip arthroplasty. A sub-study of the PANSAID trial on paracetamol and ibuprofen for postoperative pain treatment. ( Hägi-Pedersen, D; Issa, LM; Jakobsen, JC; Mathiesen, O; Overgaard, S; Thybo, KH; Wetterslev, J, 2021) |
| " When compared with placebo, total rescue opioid consumption was similar and significantly fewer intravenous acetaminophen patients prematurely discontinued because of treatment-emergent adverse events (P < ." | 2.94 | Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants. ( Cooper, DS; Devarakonda, K; Gosselin, NH; Hammer, GB; Lu, J; Maxwell, LG; Pheng, LH; Szmuk, P; Taicher, BM; Visoiu, M, 2020) |
| "Duration, postoperative pain scores, Ramsay sedation scores, analgesic consumption, and side effects were recorded in all patients during the postoperative period." | 2.94 | Comparison of tramadol versus tramadol with paracetamol for efficacy of postoperative pain management in lumbar discectomy: A randomised controlled study. ( Atalay, B; Keskin, Ö; Köner, Ö; Türe, H; Uztüre, N, 2020) |
| "The primary outcome variable was postoperative pain measured on a visual analog scale at different time points." | 2.94 | Comparison of Low Pre-Emptive Oral Doses of Celecoxib Versus Acetaminophen for Postoperative Pain Management After Third Molar Surgery: A Randomized Controlled Study. ( Li, Z; Lv, K; Xie, L; Yang, RT; Zhou, HH, 2020) |
| " The incidence of adverse events (AEs) was significantly higher in the AC group compared to NS and PBO." | 2.94 | Efficacy and safety of naproxen sodium 440 mg versus acetaminophen 600 mg/codeine phosphate 60 mg in the treatment of postoperative dental pain. ( Cattry, E; Paredes-Diaz, A; Troullos, E, 2020) |
| "Limiting harm from postoperative pain treatment is important." | 2.94 | The PANSAID randomized clinical trial: A pre-planned 1-year follow-up regarding harm. ( Hägi-Pedersen, D; Mathiesen, O; Overgaard, S; Thybo, KH; Wetterslev, J, 2020) |
| " Time to meaningful pain relief and duration of pain relief were assessed; tolerability was evaluated by adverse events." | 2.94 | Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: Results From 2 Phase 3, Randomized, Parallel-group, Double-blind, Placebo-controlled Studies. ( Cruz-Rivera, M; DePadova, E; Kellstein, D; Leyva, R; Muse, D; Paluch, E; Searle, S, 2020) |
| "Hypoxemia was defined as peripheral oxygen saturation less than 90%." | 2.94 | The relationship between postoperative opioid consumption and the incidence of hypoxemic events following total hip arthroplasty: a post hoc analysis. ( Borgeat, A; Camu, F; Cheung, R; Essex, MN; Pan, S; Salomon, PA, 2020) |
| "After craniotomy a moderate level of postoperative pain observed." | 2.94 | Effect of Intravenous Paracetamol with Bupivacaine Scalp Nerve Block on Haemodynamics Response as Well as Anaesthetic Requirements during Supratentorial Craniotomies. ( Akhtaruzzaman, AK; Chowdhury, IH; Hossain, MJ; Islam, MI; Kamal, MM, 2020) |
| "To test the hypothesis that duration of hypoxemia is less in patients given intravenous acetaminophen than those given placebo." | 2.94 | Effect of Intravenous Acetaminophen on Postoperative Hypoxemia After Abdominal Surgery: The FACTOR Randomized Clinical Trial. ( Ali Sakr Esa, W; Ayad, S; Cohen, B; Delaney, CP; Essber, H; Hovsepyan, K; Kessler, H; Maheshwari, K; Makarova, N; Mascha, EJ; Ruetzler, K; Saasouh, W; Sessler, DI; Soliman, LM; Turan, A; Yang, D, 2020) |
| "In the practice of postoperative pain management, pain is still poorly managed in low resource setting where the practice of epidural and opioid free analgesia is impractical." | 2.94 | Comparison of preemptive paracetamol, paracetamol-diclofenac & paracetamol-tramadol combination on postoperative pain after elective abdominal surgery under general anesthesia, Ethiopia: a randomized control trial study, 2018. ( Aweke, Z; Doba, DN; Seyoum, F; Shitemaw, T, 2020) |
| " Secondary outcomes included morphine consumption at 24, 48, and 72 hours after surgery, length of hospital stay, range of motion, daily ambulation distance, and adverse events occurrence." | 2.94 | Effect and safety of intravenous versus oral acetaminophen after unicompartmental knee replacement: A protocol of randomized controlled study. ( Guo, D; Li, X; Wang, H; Zhou, T, 2020) |
| "Baclofen is an agonist for a subtype of gamma-amino butyric acid (GABA-B) receptors and traditionally been used for the systemic treatment of spasticity." | 2.94 | Effect of Topical Baclofen 5% on Post-Hemorrhoidectomy Pain: Randomized Double Blind Placebo-Controlled Clinical Trial. ( Ala, S; Alvandipour, M; Mansourifar, M; Monajati, M; Saeedi, M; Shiva, A, 2020) |
| "Ibuprofen is a NSAID that has anti-inflammatory, antipyretic, and analgesic effects." | 2.94 | A Randomized, Placebo-Controlled, Double-Blind Study that Evaluates Efficacy of Intravenous Ibuprofen and Acetaminophen for Postoperative Pain Treatment Following Laparoscopic Cholecystectomy Surgery. ( Celik, EC; Ciftci, B; Ekinci, M; Karakaya, MA; Köse, EA; Ozdenkaya, Y, 2020) |
| "Dysphagia and surgical incision pain scores were also significantly lower in the LMA group, compared with the ETT group, at 6 h and 12 h after surgery." | 2.90 | Comparison Between the Protector™ Laryngeal Mask Airway and the Endotracheal Tube for Minimally Invasive Thyroid and Parathyroid Surgery. ( Gkinas, D; Kotsovolis, G; Panidis, S; Papavramidis, T; Pliakos, I, 2019) |
| "Secondary outcome measures are postoperative pain intensity scores, psychological parameters, length of hospital stay and adverse events and will be reassessed at 3 and 6 months after surgery, with a baseline measurement preoperatively." | 2.90 | Assessing the effectiveness of perioperative s-ketamine on new-onset headache after resective epilepsy surgery (ESPAIN-trial): protocol for a randomised, double-blind, placebo-controlled trial. ( Bastiaenen, C; Bos, M; Colon, A; Dings, J; Hoogland, G; Rijkers, K; Rouhl, RPW; Schijns, OEMG; Sloekers, JCT; Theunissen, M; van Kuijk, S, 2019) |
| "To determine which non-narcotic analgesic, acetaminophen (Ofirmev®) or ketorolac (Toradol®), provides better post-operative pain control when combined with an opioid patient-controlled analgesia (PCA) pump." | 2.90 | A prospective randomized trial of intravenous ketorolac vs. acetaminophen administered with opioid patient-controlled analgesia in gynecologic surgery. ( Ahmad, S; Bigsby, GE; Ghurani, GB; Holloway, RW; James, JA; Jeppson, CN; Kendrick, JE; Rakowski, JA, 2019) |
| "Remifentanil can provide better postoperative pain control than apotel immediately after surgery." | 2.90 | The Effects of Apotel and Remifentanil on Postoperative Pain. ( Kamali, A; Mortazavi, L; Shokrpour, M; Vakilian, K, 2019) |
| "Pathophysiology of postoperative pain in spine surgery is unique, as it is a combination of nociceptive, inflammatory, and neuronal stimuli." | 2.90 | A prospective randomized study to analyze the efficacy of balanced pre-emptive analgesia in spine surgery. ( Kanna, RM; Raja S, DC; Rajasekaran, S; Shetty, AP; Subramanian, B, 2019) |
| "The difference in postoperative pain was assessed by 4 primary end-points: pain intensity (VAS 100mm, for 48 h), rescue medication, overall assessment and adverse effects." | 2.90 | Analgesic efficacy of ketorolac associated with a tramadol/acetaminophen combination after third molar surgery - a randomized, triple-blind clinical trial. ( Bortoluzzi, MC; Loguercio, AD; Martins, LD; Reis, A; Rezende, M, 2019) |
| " It was hypothesized that 1000 mg of intravenous acetaminophen (IA) dosed every 6 hours would significantly reduce the postoperative pain score at rest and the opioid consumption volume in patients who would undergo total hip arthroplasty (THA) when compared to a control group." | 2.90 | Evaluating the Effect of Intravenous Acetaminophen in Multimodal Analgesia After Total Hip Arthroplasty: A Randomized Controlled Trial. ( Fukunishi, S; Hashimoto, K; Nishio, S; Simura, Y; Takeda, Y; Yoshiya, S, 2019) |
| "FICB improved postoperative pain on movement compared with intravenous acetaminophen without increasing the complication rate." | 2.90 | Comparison of the postoperative analgesic efficacies of intravenous acetaminophen and fascia iliaca compartment block in hip fracture surgery: A randomised controlled trial. ( Dan'ura, T; Matsui, Y; Nishiyama, A; Noda, T; Ozaki, T; Sakura, S; Yamamoto, N, 2019) |
| "Ibuprofen is an effective analgesic after tonsillectomy alone or tonsillectomy with adenoidectomy, but concerns remain about whether it increases postoperative hemorrhage." | 2.90 | Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial. ( Bennett, K; Boseley, M; Brigger, M; Cohen, MS; Comins, J; Diercks, GR; Gallagher, TQ; Gaudreau, P; Hartnick, C; Keamy, D; Rogers, D; Setlur, J, 2019) |
| "Average postoperative pain intensity using a numerical rating scale and use of rescue medication were measured in the postanaesthesia care unit (PACU) and on postoperative days (POD) 1 to 3." | 2.90 | Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial. ( Boon, M; Buhre, WFFA; Evers, S; Joosten, EA; Ory, JP; Pelckmans, C; Stessel, B; Van de Velde, M; van Kuijk, SMJ; Wyckmans, W, 2019) |
| "Patient satisfaction with overall postoperative pain management was significantly higher in the IV acetaminophen group than the placebo group on a 1 to 10 scale (8." | 2.87 | Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study. ( Aijazi, H; Artime, CA; Cai, C; Ferrario, L; Gumbert, SD; Hagberg, CA; Normand, KC; Syed, T; Williams, GW; Zhang, H, 2018) |
| "I." | 2.87 | Randomized trial of oral versus intravenous acetaminophen for postoperative pain control. ( Bradford, LM; Garman, CD; Gregg, RW; Hickman, SR; Lukens, DW; Mathieson, KM, 2018) |
| "The patients' postoperative pain scores at 4 and 24 hours were collected via a verbal rating scale by the primary investigator." | 2.87 | Use of Intravenous Acetaminophen in Postoperative Pain Management After Partial and Full Bony Impacted Third Molar Extractions: A Randomized Double-Blind Controlled Trial. ( Atencio, I; Baur, DA; Beushausen, M; Fino, NF; Flores-Hidalgo, A; Kowalczyk, JJ, 2018) |
| "Postoperative pain is a frequent cause for delayed discharge following outpatient procedures, including anorectal surgery." | 2.87 | Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial. ( Callas, P; Cataldo, PA; Dominick, T; Jordan, MR; Leahy, DT; Moore, JS; Van Backer, JT, 2018) |
| "The increasing rate of opioid abuse warrants standardization of postoperative pain management." | 2.87 | Opioid Use following Outpatient Breast Surgery: Are Physicians Part of the Problem? ( Broecker, JS; Hart, AM; Kao, L; Losken, A, 2018) |
| "We also aimed to compare postoperative pain levels and side effects of the drugs." | 2.87 | Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial. ( Erdogan Kayhan, G; Kirteke, R; Ozgul, U; Sanli, M; Yologlu, S, 2018) |
| "We evaluated postoperative pain control and narcotic usage after thumb carpometacarpal (CMC) arthroplasty or open reduction and internal fixation (ORIF) of the distal radius in patients given opiates with or without other non-opiate medication using a specific dosing regimen." | 2.87 | Multi-Modal Pain Control in Ambulatory Hand Surgery. ( Awan, HM; DiMeo, T; Harrison, RK; Klinefelter, RD; Ruff, ME, 2018) |
| "Acute pain is a significant burden to the individual and to society." | 2.87 | Analgesic Efficacy of an Acetaminophen/Ibuprofen Fixed-dose Combination in Moderate to Severe Postoperative Dental Pain: A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial. ( Atkinson, HC; Daniels, SE; Frampton, C; Stanescu, I, 2018) |
| "Adequate postoperative pain control in hand surgery is a multifactorial issue affecting patient satisfaction, outcomes, and safety." | 2.87 | Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone. ( Graham, JG; Ilyas, AM; Matzon, JL; Miller, AJ, 2018) |
| "To reduce postoperative pain by using additional analgesic agent in between the usual parenteral analgesia that is used in the postoperative period in surgical patients." | 2.87 | Effectiveness of acetaminophen in control of breakthrough pain: Randomized controlled trial. ( Bangash, AA; Durrani, Z, 2018) |
| " Blood samples were collected for pharmacokinetic analysis for up to 6 hours after the loading dose." | 2.87 | Analgesic effectiveness, pharmacokinetics, and safety of a paracetamol/ibuprofen fixed-dose combination in children undergoing adenotonsillectomy: A randomized, single-blind, parallel group trial. ( Anderson, BJ; Atkinson, HC; Frampton, C; Playne, R; Stanescu, I, 2018) |
| "The amount of postoperative pain was measured on the basis of visual analog scale, arterial blood pressure, as well as heart rate at recovery and 4, 12, and 24 hours after surgery." | 2.87 | A comparative study on the prophylactic effects of paracetamol and dexmedetomidine for controlling hemodynamics during surgery and postoperative pain in patients with laparoscopic cholecystectomy. ( Ashrafi, TH; Kamali, A; Noori, G; Norouzi, A; Rakei, S, 2018) |
| "No studies have examined postoperative pain control following transsphenoidal surgery for pituitary lesions." | 2.87 | Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery. ( Jahnke, H; Little, AS; Shepherd, DM; White, WL, 2018) |
| "Nefopam is a centrally acting analgesic which has a theoretical risk of stopping lactation due to its anticholinergic and dopaminergic effects." | 2.84 | The effect of nefopam on lactation after caesarean section: a single-blind randomised trial. ( Baka, NE; Bouaziz, H; Guerci, P; Hubert, C; Iohom, G; Rouabah, M; Vial, F, 2017) |
| "Postoperative pain is a common complaint in day-case inguinal herniotomy, thus there is a need to provide effective analgesia." | 2.84 | The analgesic effects of rectal diclofenac versus rectal paracetamol following caudal-bupivacaine for pediatric day-case inguinal herniotomies: a randomized controlled prospective trial. ( Ebirim, L; Nnaji, CT; Onajin-Obembe, B, 2017) |
| "The primary outcome was postoperative pain measured by visual analog scale (VAS) scores up to 24 hours after surgery by blinded observers." | 2.84 | Analgesic Effects of Intravenous Acetaminophen vs Placebo for Endoscopic Sinus Surgery and Postoperative Pain: A Randomized Clinical Trial. ( Ashoori, F; Cai, C; Cattano, D; Citardi, MJ; Fakhri, S; Kain, JJ; Lam, K; Luong, A; Tyler, MA, 2017) |
| "Postoperative pain was assessed using the visual analog scale (VAS) every 3 hours (while awake) for the first 48 hours after surgery." | 2.84 | Efficacy of Codeine When Added to Paracetamol (Acetaminophen) and Ibuprofen for Relief of Postoperative Pain After Surgical Removal of Impacted Third Molars: A Double-Blinded Randomized Control Trial. ( Best, AD; Cameron, CM; De Silva, HL; De Silva, RK; Thomson, WM; Tong, DC, 2017) |
| "Management of postoperative pain is a common problem in endoscopic sinus surgery." | 2.84 | Administering of pregabalin and acetaminophen on management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery. ( Rezaeian, A, 2017) |
| "PCA morphine consumption was recorded and postoperative pain was evaluated by Visual Analog Scale (VAS) in postoperative recovery room, at the 1st, 2nd, 4th, 8th, 12th, 24th, 36th, and 48th hours." | 2.84 | Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery. ( Doğan, R; Karaca, Ö; Karakoç, F; Pınar, HU, 2017) |
| "POST, hoarseness, and dysphagia were monitored." | 2.84 | Combined intraoperative paracetamol and preoperative dexamethasone reduces postoperative sore throat: a prospective randomized study. ( Jeong, MH; Kim, HC; Lee, J; Park, HP, 2017) |
| "Effective postoperative pain management is essential for the rehabilitation of the surgical patient." | 2.84 | PANSAID-PAracetamol and NSAID in combination: detailed statistical analysis plan for a randomised, blinded, parallel, four-group multicentre clinical trial. ( Bjørck, JG; Bülow, HH; Dahl, JB; Hägi-Pedersen, D; Jakobsen, JC; Mathiesen, O; Overgaard, S; Pedersen, NA; Schrøder, HM; Thybo, KH; Wetterslev, J, 2017) |
| "Postoperative pain is a common clinical problem that greatly affects the length of hospitalization, functional status and patient quality of life." | 2.84 | Analgesic Effect - Comparison of Paracetamol Administered Intermittently and Through Patient-Controlled Analgesia Pump after Lumbar Discectomy: a Prospective Clinical Study. ( Božić, B; Kalauz, S; Kurtović, B; Milošević, M; Mladić Batinica, I; Rotim, K, 2017) |
| "Morphine consumption was comparable between the two groups both at H48, 38 mg (26:52) (median, 25th:75th percentile) (control group) versus 43 mg (19:74) (ropivacaine group), and at H24, 18 mg (16:22) versus 22 mg (9:35) respectively." | 2.84 | Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study. ( Albaladejo, P; Bosson, JL; Greze, J; Incagnoli, P; Palombi, O; Payen, JF; Quesada, JL; Tonetti, J; Vighetti, A, 2017) |
| "Postoperative pain is a common problem in hospitals." | 2.84 | Effect of intravenous vitamin C on postoperative pain in uvulopalatopharyngoplasty with tonsillectomy. ( Ayatollahi, V; Behdad, S; Dehghanpour Farashah, S; Rabbani Anari, M; Vaziribozorg, S, 2017) |
| "Data were compared with respect to postoperative pain with visual analog scale (VAS) and analgesic consumption, documented in a pain diary for 2 weeks after surgery." | 2.84 | Preemptive Analgesia in Hip Arthroscopy: A Randomized Controlled Trial of Preemptive Periacetabular or Intra-articular Bupivacaine in Addition to Postoperative Intra-articular Bupivacaine. ( Amar, E; Brill, S; Drexler, M; Kazum, E; Martin, HD; Paret, M; Rath, E; Sharfman, ZT; Shlaifer, A; Warschawski, Y, 2017) |
| "Atorvastatin is a 3-hydroxy-3-methylglutaryl coenzyme A (HMG CoA) reductase inhibitor widely used in treatment of hypercholesterolemia and prevention of coronary heart disease and has various pleiotropic effects." | 2.84 | Effects of Topical Atorvastatin (2 %) on Posthemorrhoidectomy Pain and Wound Healing: A Randomized Double-Blind Placebo-Controlled Clinical Trial. ( Ala, S; Alvandipour, M; Faramarzi, F; Hamidian, M; Rahmani, N; Saeedi, M; Shiva, A, 2017) |
| "DXM appears to decrease postoperative pain and thus is recommended as a pre-emptive analgesic in blowout fracture surgery." | 2.84 | Analgesic Effect of Perioperative Systemic Dexamethasone on Blowout Fracture Surgery. ( Koivusalo, AM; Kormi, E; Snäll, J; Suominen, AL; Thorén, H; Törnwall, J, 2017) |
| "The management of postoperative pain is a major health care issue." | 2.84 | A Preliminary Examination of the Comparative Efficacy of Intravenous vs Oral Acetaminophen in the Treatment of Perioperative Pain. ( Bartoszek, M; Beltran, T; Berry-Caban, C; Haley, C; Highland, KB; Lamberth, S; McCoart, A; Plunkett, A, 2017) |
| "Effective postoperative pain management is essential for the rehabilitation of the surgical patient." | 2.84 | PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial. ( Bjørck, JG; Bülow, HH; Dahl, JB; Hägi-Pedersen, D; Mathiesen, O; Schrøder, HM; Thybo, KH; Wetterslev, J, 2017) |
| "The celecoxib-treated group experienced significantly more vomiting (celecoxib vs placebo p < 0." | 2.84 | Is celecoxib a useful adjunct in the treatment of post-tonsillectomy pain in the adult population? A randomised, double-blind, placebo-controlled study. ( De Silva, N; Diamantaras, D; Mahanta, V; Ng, TT; Priestley, J; Redman, J, 2017) |
| "Because nefopam's morphine-sparing is debated when combined with paracetamol, this study aimed to assess pain relief by IV nefopam in combination with paracetamol after major abdominal surgery." | 2.84 | Opioid-sparing effect of nefopam in combination with paracetamol after major abdominal surgery: a randomized double-blind study. ( Alonso, S; Casano, F; Cuvillon, P; Demattei, C; L'hermite, J; Lefrant, JY; Muller, L; Ripart, J; Zoric, L, 2017) |
| "Acetaminophen is a widely clinically used analgesic." | 2.82 | Comparison of intravenous and oral administration of acetaminophen in adults undergoing general anesthesia. ( Cao, Q; Dong, H; Fan, C; Meng, H; Yuan, R; Zhang, S, 2022) |
| " Intravenous (iv) acetaminophen has been reported to have superior efficacy and bioavailability than oral acetaminophen." | 2.82 | Effect of intravenous acetaminophen on postoperative outcomes in hip fracture patients: a systematic review and narrative synthesis. ( Cho, JSH; Clarke, H; Engelsakis, M; Jacob, B; Karkouti, K; McCarthy, K; McCluskey, S; Schiavo, S; Wong, J; Zywiel, M, 2022) |
| " Gabapentenoid dosing varied among studies." | 2.82 | Gabapentinoids and Acetaminophen as Adjuvants for Managing Postoperative Pain. ( Gill, C; Giuliano, K, 2022) |
| "The PROSPECT (PROcedure SPEcific Postoperative Pain ManagemenT) Working Group is a global collaboration of surgeons and anaesthesiologists formulating procedure-specific recommendations for pain management after common operations." | 2.82 | Pain management after total knee arthroplasty: PROcedure SPEcific Postoperative Pain ManagemenT recommendations. ( Joshi, GP; Kehlet, H; Lavand'homme, PM; Rawal, N, 2022) |
| "ESPB was an efficient and safe procedure for postoperative pain management in PCNL." | 2.82 | Efficiency and Safety of Erector Spinae Plane Block in Percutaneous Nephrolithotomy: A Meta-Analysis Based on Randomized Controlled Trials. ( Jin, T; Lin, L; Luo, Z; Ma, Y; Xiao, K, 2022) |
| "Postoperative pain after head and neck cancer surgery is commonly treated with opioids, which are associated with considerable side effects." | 2.82 | Multimodal Analgesia in Head and Neck Free Flap Reconstruction: A Systematic Review. ( Chorath, K; Go, BC; Go, CC; Moreira, A; Rajasekaran, K, 2022) |
| "Intravenous APAP use in postsurgical pain management has been reported to decrease opioid usage, time to rescue dose, and subjective pain." | 2.82 | Randomized trial of OFIRMEV versus placebo for pain management after laparoscopic sleeve gastrectomy. ( Bland, CM; Choi, YU; Faler, BJ; Mangieri, CW; Prasad, BM; Sherman, W; Sparks, PJ; Strode, MA, 2016) |
| "Success was defined as no or mild postoperative pain and no use of escape medication." | 2.82 | What is the Effect of No Endodontic Debridement on Postoperative Pain for Symptomatic Teeth with Pulpal Necrosis? ( Beck, M; Drum, M; Fowler, S; Nusstein, J; Reader, A; Sebastian, R, 2016) |
| "Using IV acetaminophen for postoperative pain management produced notable indirect cost savings and reduced ED visits in the first 30 days postoperatively, with good safety and tolerance." | 2.82 | IV Acetaminophen Results in Lower Hospital Costs and Emergency Room Visits Following Bariatric Surgery: a Double-Blind, Prospective, Randomized Trial in a Single Accredited Bariatric Center. ( Claros, L; El Chaar, M; Stoltzfus, J; Wasylik, T, 2016) |
| "Acetaminophen is known to be a relatively weak analgesic with fewer side effects than nonsteroidal anti-inflammatory drugs (NSAIDs)." | 2.82 | Comparison of the analgesic effect of intravenous acetaminophen with that of flurbiprofen axetil on post-breast surgery pain: a randomized controlled trial. ( Hara, M; Miyamoto, C; Nonaka, T; Sugita, M; Yamamoto, T, 2016) |
| "Acetaminophen was superior to placebo on mean pain intensity scores and noninferior on opioid consumption, with estimated difference in mean pain (95% confidence interval) of -0." | 2.82 | Intravenous acetaminophen analgesia after cardiac surgery: A randomized, blinded, controlled superiority trial. ( Duncan, AE; Insler, SR; Lin, P; Mamoun, NF; Mascha, EJ; Mick, SL; Sessler, DI; Zimmerman, NM, 2016) |
| "Celecoxib is a cyclooxygenase-2-specific inhibitor indicated to treat acute pain and pain secondary to osteoarthritis and rheumatoid arthritis." | 2.82 | Celecoxib Versus Placebo in Tonsillectomy: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial. ( Bodeker, KL; Trask, DK; Van Daele, DJ, 2016) |
| "IV acetaminophen has also been shown to be effective in alleviating pain for surgical procedures." | 2.82 | A Randomized Trial Comparing the Safety and Efficacy of Intravenous Ibuprofen versus Ibuprofen and Acetaminophen in Knee or Hip Arthroplasty. ( Abubaker, H; Ahrendtsen, L; Demas, E; Gupta, A, 2016) |
| " The secondary outcomes included 48-hour postoperative opioid consumption, incisional pain scores, opioid-related adverse effects, length of mechanical ventilation, length of intensive care unit stay, and the extent of wound hyperalgesia assessed at 24 and 48 hours postoperatively." | 2.82 | Intravenous Acetaminophen as an Adjunct Analgesic in Cardiac Surgery Reduces Opioid Consumption But Not Opioid-Related Adverse Effects: A Randomized Controlled Trial. ( Bollag, L; Bowdle, A; Cain, KC; Jelacic, S; Richebe, P; Rivat, C, 2016) |
| " Despite this approval, pediatric pharmacokinetic data using this product have not been previously published." | 2.80 | Pharmacokinetics of hydrocodone/acetaminophen combination product in children ages 6-17 with moderate to moderately severe postoperative pain. ( Awni, W; Dutta, S; Kearns, G; Liu, W; Neville, KA, 2015) |
| " Secondary endpoints included SPID at additional time points, total pain relief at all on-therapy time points (TOTPAR), sum of SPID and TOTPAR at all on-therapy time points (SPID + TOTPAR), use of rescue medication, subjective pain assessment (PGIC, Patient Global Impression of Change), and adverse events (AEs)." | 2.80 | A randomized study to compare the efficacy and safety of extended-release and immediate-release tramadol HCl/acetaminophen in patients with acute pain following total knee replacement. ( Bin, SI; Chang, N; Cho, SD; Choi, CH; Ha, CW; Kang, SB; Kyung, HS; Lee, JH; Lee, MC; Park, YB; Rhim, HY; Seo, SS, 2015) |
| " The present study was intended to understand the pharmacodynamic interaction between paracetamol and ondansetron in postoperative patients." | 2.80 | Randomized, double-blind, placebo-controlled study to investigate the pharmacodynamic interaction of 5-HT3 antagonist ondansetron and paracetamol in postoperative patients operated in an ENT department under local anesthesia. ( Bhosale, UA; Kale, J; Khobragade, R; Naik, C; Yegnanarayan, R, 2015) |
| "Gabapentin was investigated as a single-dose adjunct to morphine for postoperative pain management." | 2.80 | Randomized controlled trial of gabapentin as an adjunct to perioperative analgesia in total hip arthroplasty patients. ( Avram, V; Buckley, N; Cheng, J; DeBeer, J; Nantha-Aree, M; Paul, JE; Punthakee, D; Shahzad, U; Thabane, L; Tidy, A; Winemaker, M; Wismer, D, 2015) |
| "Combined paracetamol and ibuprofen has been shown to be more effective than either constituent alone for acute pain in adults, but the dose-response has not been confirmed." | 2.80 | Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study. ( Atkinson, HC; Bisley, E; Carson, S; Currie, J; Evans, S; Frampton, C; Moodie, J; Steenberg, LJ; Worthington, JP, 2015) |
| " Safety was monitored through adverse event reporting." | 2.80 | Comparison of the efficacy and safety of different doses of propacetamol for postoperative pain control after breast surgery. ( Kang, JE; Kim, HS; Kim, JT; Lee, JH; Park, SK; Song, IK, 2015) |
| "The surgical treatment of hallux valgus deformity is connected with significant postoperative pain." | 2.80 | [Preemptive local anesthetic infiltration in hallux valgus one-day surgery]. ( Gądek, A; Liszka, H, 2015) |
| "Tramadol was more effective in the treatment of postoperative pain after lumbar disc surgery." | 2.80 | Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery. ( Çaglar Torun, A; Kelsaka, E; Köksal, E; Kuruoğlu, E; Sarihasan, BB; Taş, N; Yilmaz, MZ, 2015) |
| " Blood samples were collected for pharmacokinetic analysis of study drugs and their metabolites over an 8-hour period beginning after the second dose of the study medication." | 2.80 | Pharmacokinetics of hydrocodone and tramadol administered for control of postoperative pain in dogs following tibial plateau leveling osteotomy. ( Benitez, ME; KuKanich, B; McMurphy, R; Roush, JK, 2015) |
| "Tramadol consumption was lower in Group P and Group N, compared with Group C (p < 0." | 2.80 | Comparison of the postoperative analgesic effects of paracetamol-codeine phosphate and naproxen sodium-codeine phosphate for lumbar disk surgery. ( Akkaya, T; Ergil, J; Gülöksüz, ÇT; Peker, K; Polat, R, 2015) |
| "This study was conducted to determine if intravenous dexamethasone combined with caudal block was able to prolong post-operative analgesia in pediatric daycare surgeries." | 2.80 | INTRAVENOUS DEXAMETHASONE IN COMBINATION WITH CAUDAL BLOCK PROLONGS POSTOPERATIVE ANALGESIA IN PEDIATRIC DAYCARE SURGERY. ( Azarinah, I; Esa, K; Hamidah, I; Khairulamir, Z; Murni Sari Ahmad, A; Norsidah Abdul, M, 2015) |
| "Today, parents are more involved with postoperative pain management, because children are discharged as early as possible after surgery." | 2.79 | A randomized controlled trial of the effectiveness of educating parents about distraction to decrease postoperative pain in children at home after tonsillectomy. ( Helgadóttir, HL; Wilson, ME, 2014) |
| "Paracetamol is widely used to treat postoperative pain and is well known for its morphine-sparing effect." | 2.79 | Median effective dose (ED₅₀) of paracetamol and morphine for postoperative pain: a study of interaction. ( Ali Abdullah, M; Ghattas, T; Maaliki, H; Mazoit, JX; Saifan, A; Zeidan, A, 2014) |
| "The difference in postoperative pain was assessed by four primary points: pain intensity as measured by a 10 mm visual analogue scale hourly for 12 h, median time to rescue analgesics, number of analgesics consumed and patient's overall 5-point global assessment scale." | 2.79 | Comparative study of intravenous Tramadol versus Ketorolac for preventing postoperative pain after third molar surgery--a prospective randomized study. ( Gopalraju, P; Lalitha, RM; Prasad, K; Ranganath, K, 2014) |
| "Diclofenac dosing in children for analgesia is currently extrapolated from adult data." | 2.79 | Postoperative analgesia using diclofenac and acetaminophen in children. ( Anderson, BJ; Hannam, JA; Holford, NH; Mahadevan, M, 2014) |
| " When comparing all three groups, a statistically significant dose-response relationship was seen for present, average and worst pain intensity after 8 h and on the following morning." | 2.79 | Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial. ( Bjørnholdt, KT; Mønsted, PN; Nikolajsen, L; Søballe, K, 2014) |
| " The dosage of narcotics can be decreased (that of trimeperidine on an average from 80 to 45 mg/day) in the early postoperative period if non-narcotic analgesics, such as paracetamol 4 g/day, are incorporated into the analgesic regimen." | 2.79 | [Analgesia in hemophiliac patients during orthopedic surgery]. ( Gemdzhian, ÉG; Gorodetskiĭ, VM; Koniashina, NI; Krechetova, AV; Levchenko, OK; Shulutko, EM, 2014) |
| "Postoperative pain was assessed by use of the visual analog scale (VAS)." | 2.79 | Effect of preoperative administration of intravenous paracetamol during cesarean surgery on hemodynamic variables relative to intubation, postoperative pain and neonatal apgar. ( Ayatollahi, V; Baghianimoghadam, B; Behdad, S; Faghihi, S; Heiranizadeh, N, 2014) |
| "The Parent's Postoperative Pain Measure scores of control group children were significantly higher within the first 3 post-operative days (p = 0." | 2.78 | Pre-emptive triple analgesia protocol for tonsillectomy pain control in children: double-blind, randomised, controlled, clinical trial. ( El-Fattah, AM; Ramzy, E, 2013) |
| " Moderate to severe gastrointestinal adverse events occurred in 50% of patients in the oxycodone/acetaminophen group compared with 15% of the equianalgesic morphine/oxycodone group." | 2.78 | Comparison of the efficacy and safety of dual-opioid treatment with morphine plus oxycodone versus oxycodone/acetaminophen for moderate to severe acute pain after total knee arthroplasty. ( Gimbel, JS; Kelen, R; Minkowitz, HS; Richards, P; Stern, W, 2013) |
| "To compare postoperative pain scores and rescue analgesic use in patients who received acetaminophen preoperatively or during skin closure versus those who received a placebo." | 2.78 | Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery. ( Emaminejad, A; Janghorbani, M; Khalili, G; Saryazdi, H, 2013) |
| "For the treatment of postoperative pain, 30 patients constituted group F and received a 12." | 2.78 | Postoperative fentanyl patch versus subacromial bupivacaine infusion in arthroscopic shoulder surgery. ( Aantaa, R; Äärimaa, V; Koivisto, M; Kuusniemi, K; Leino, K; Liukas, A; Merivirta, R, 2013) |
| " Efficacy and rapid onset also reduce the risk of excessive dosing with the analgesic." | 2.78 | Efficacy and speed of onset of pain relief of fast-dissolving paracetamol on postsurgical dental pain: two randomized, single-dose, double-blind, placebo-controlled clinical studies. ( Brown, J; Buchanan, WL; Collaku, A; Cooper, SA; Otto, J; Reed, K; Yue, Y, 2013) |
| "In morphine group, it was higher after 4, 6 and 8 hours." | 2.78 | The postoperative analgesic effect of morphine and paracetamol in the patients undergoing laparotomy, using PCA method. ( Barikani, A; Kayalha, H; Pourfallah, R; Yaghoubi, S, 2013) |
| "The primary outcome was a reduction in postoperative pain as assessed by a visual analogue scale (VAS)." | 2.78 | Intravesical ropivacaine as a novel means of analgesia post-robot-assisted radical prostatectomy: a randomized, double-blind, placebo-controlled trial. ( Fuller, A; Martin, PR; Nott, L; Pautler, SE; Vanderhaeghe, L, 2013) |
| " Rescue medication consumption, requests, and actual administration were all significantly lower in the IV acetaminophen group compared with placebo for each dosing interval, except in the 6- to 12-hours interval where a numerical trend was observed." | 2.77 | Intravenous acetaminophen for pain after major orthopedic surgery: an expanded analysis. ( Breitmeyer, JB; Groudine, SB; Jahr, JS; Reynolds, L; Royal, MA; Sinatra, RS; Viscusi, ER, 2012) |
| "Dexamethasone also reduced postoperative pain after LITM surgical extraction significantly on postoperative days 2 and 7." | 2.77 | Effect of single dose preoperative intramuscular dexamethasone injection on lower impacted third molar surgery. ( Boonsiriseth, K; Kaewpradub, P; Klongnoi, B; Wongsirichat, N, 2012) |
| "Postoperative pain was assessed with a visual analogue scale at 4, 6, 12, 24, and 48 h postoperatively (p." | 2.77 | Comparative study of tramadol combined with dexamethasone and diclofenac sodium in third-molar surgery. ( Brandão, JR; da Silva, LC; de Assunção Oliveira, AC; de Santana Santos, T; de Sousa Santos, JA; Menezes Júnior, LR, 2012) |
| "Secondary outcomes included postoperative pain scores, rescue analgesia requirements and duration of stay in the recovery room." | 2.77 | Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: a double-blind randomised controlled trial. ( Barnett, SG; Brett, CN; Pearson, J, 2012) |
| "The purpose of this study, in a sample of preschool children (ages 3-5 years; N = 47), was to evaluate the feasibility of scheduled analgesic dosing following outpatient tonsillectomy in order to optimize pain management." | 2.77 | A descriptive feasibility study to evaluate scheduled oral analgesic dosing at home for the management of postoperative pain in preschool children following tonsillectomy. ( Holdridge-Zeuner, D; Lanier, B; Mahoney, K; Miaskowski, C; Paul, SM; Savedra, MC; Sutters, KA; Waite, S, 2012) |
| "Sixty patients who sustained moderate postsurgical pain (visual analog scale(3)3 cm) after undergoing implantation of venous access were randomized to two groups to receive either Ultracetor Depain-X for postoperative analgesia." | 2.77 | Analgesic efficacy of tramadol/acetaminophen and propoxyphene/acetaminophen for relief of postoperative wound pain. ( Chen, CY; Lai, CH; Lin, CP; Lin, FS; Lin, TF; Lin, WY; Sun, WZ, 2012) |
| "A significantly lower postoperative pain intensity was only found in the parecoxib group at 24 h after surgery compared to the metamizol group." | 2.77 | A randomized, double-blind, controlled trial on non-opioid analgesics and opioid consumption for postoperative pain relief after laparoscopic cholecystectomy. ( Abdulla, S; Abdulla, W; Eckhardt, R; Netter, U, 2012) |
| "Morphine consumption was statistically lower in the TPVB group than in the PCA group at 24 h (P = 0." | 2.77 | Comparison between systemic analgesia, continuous wound catheter analgesia and continuous thoracic paravertebral block: a randomised, controlled trial of postthoracotomy pain management. ( Bernard, A; Fortier, S; Girard, C; Hanna, HA, 2012) |
| "Emergence agitation and postoperative pain were assessed, recorded and compared." | 2.77 | A randomized evaluation of intravenous dexamethasone versus oral acetaminophen codeine in pediatric adenotonsillectomy: emergence agitation and analgesia. ( Hosseini, B; Khalili, G; Sajedi, P; Seyyedyousefi, H; Shafa, A, 2012) |
| "The intensity of postoperative pain was recorded on a visual analogue scale (VAS), and postoperative requests for analgesia, haemodynamic variables (systolic blood pressure and heart rate), and complications were compared." | 2.76 | Postoperative analgesia in orthognathic surgery patients: diclofenac sodium or paracetamol? ( Cambazoğlu, M; Cimen, E; Küçükyavuz, Z; Oncül, AM, 2011) |
| " Piritramide dosage and incidence of side effects were not reduced." | 2.76 | Efficacy of intravenous paracetamol compared to dipyrone and parecoxib for postoperative pain management after minor-to-intermediate surgery: a randomised, double-blind trial. ( Brodner, G; Cosanne, I; Ellger, B; Freise, H; Gogarten, W; Hahnenkamp, K; Huppertz-Thyssen, M; Van Aken, H; Wempe, C, 2011) |
| "To evaluate the efficacy of intraoperative local anesthetic infiltration in combination with intravenous paracetamol infusion on postoperative pain management in patients who underwent percutaneous nephrolithotomy (PCNL)." | 2.76 | Efficacy of levobupivacaine infiltration to nephrosthomy tract in combination with intravenous paracetamol on postoperative analgesia in percutaneous nephrolithotomy patients. ( Dogan, HS; Gokten, OE; Kilicarslan, H; Kordan, Y; Turker, G, 2011) |
| "In summary, pain, trismus and swelling after lower third molar extraction, independent of surgical difficulty, could be controlled by piroxicam 20mg administered orally or sublingually and no significant differences were observed between the route of delivery used in this study." | 2.76 | Comparison of oral versus sublingual piroxicam during postoperative pain management after lower third molar extraction. ( Brozoski, DT; Calvo, AM; Colombini-Ishikiriama, BL; Dionísio, TJ; Faria, FA; Giglio, FP; Lauris, JR; Modena, KC; Ribeiro, DA; Santos, CF; Trindade, PA, 2011) |
| "Postoperative pain is an adverse effect of periodontal surgeries and may therefore be prevented or minimized." | 2.76 | The use of etoricoxib and celecoxib for pain prevention after periodontal surgery: a double-masked, parallel-group, placebo-controlled, randomized clinical trial. ( Pilatti, GL; Santos, FA; Steffens, JP, 2011) |
| "When added to a standardized postoperative pain regimen, gabapentin use led to no additional improvement in PRK pain control compared with a placebo at the dose and the time intervals tested." | 2.76 | Oral gabapentin for photorefractive keratectomy pain. ( Bower, KS; Coe, CD; Eaddy, J; Edwards, J; Howard, RS; Kuhnle, MD; Kuzmowych, C; Ryan, DS, 2011) |
| "Nicotine treatment was associated with a highly significant decrease in pain reported during the 5 days after TM surgery." | 2.76 | Nicotine nasal spray as an adjuvant analgesic for third molar surgery. ( Afzali, P; Akkara, J; Alfi, DM; Conell-Price, J; Eisig, SB; Flood, P; Olson, L; Yagoubian, B; Yeh, J, 2011) |
| "The frequency of postoperative nausea and vomiting also was noted." | 2.76 | The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children. ( Baltaci, B; Başar, H; Takmaz, SA; Uysal, HY; Yaman, F, 2011) |
| "Postoperative pain was treated with patient-controlled intravenous hydromorphone 0." | 2.76 | The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy. ( Lee, J; Lee, YK; Moon, DE; Moon, YE, 2011) |
| "The extent of mechanical dynamic hyperalgesia on the middle line perpendicular to the wound was considered the primary endpoint." | 2.76 | Target-controlled dosing of remifentanil during cardiac surgery reduces postoperative hyperalgesia. ( Cahana, A; Calderon, J; Janvier, G; Jelacic, S; Mehta, S; Picard, W; Pouquet, O; Richebé, P; Rivat, C, 2011) |
| "The ibuprofen dose range was 100-400 mg, and acetaminophen dose range was 500-1000 mg." | 2.76 | Explaining the acetaminophen-ibuprofen analgesic interaction using a response surface model. ( Anderson, BJ; Hannam, J, 2011) |
| "and group L 8 mg lornoxicam i." | 2.76 | Postoperative analgesia in impacted third molar surgery: the role of preoperative diclofenac sodium, paracetamol and lornoxicam. ( Alanoglu, Z; Demiralp, S; Ozturk, A; Tuzuner Oncul, AM; Ucok, C; Yazicioglu, D, 2011) |
| "To evaluate postoperative pain using a multimodal analgesic protocol in women with uterine fibroids managed with minimally invasive myomectomy." | 2.76 | Improved recovery using multimodal perioperative analgesia in minimally invasive myomectomy: a randomised study. ( Kalogiannidis, I; Papadopoulos, E; Prapas, N; Prapas, Y; Xiromeritis, P, 2011) |
| "Postoperative pain was assessed regularly with the Children Hospital of Eastern Ontario Pain Scale, and rescue analgesia was provided if scores were 7 or greater." | 2.76 | Effect of rectal diclofenac and acetaminophen alone and in combination on postoperative pain after cleft palate repair in children. ( Makarem, J; Mireskandari, SM, 2011) |
| "The authors assessed the participants' postoperative pain by means of a visual analog scale at four, six, eight, 12, 24 and 48 hours." | 2.76 | Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction. ( Calazans, AC; de Oliveira E Silva, ED; de Santana Santos, T; Gomes, AC; Martins-Filho, PR; Silva, LC, 2011) |
| "The degree of satisfaction with postoperative pain management was excellent in 90% in Groups L and P, versus in only 30% in Group C." | 2.76 | [Comparison of the analgesic effects of intravenous paracetamol and lornoxicam in postoperative pain following thyroidectomies]. ( Arslan, M; Celep, B; Ciçek, R; Ustün Kalender, H; Yılmaz, H, 2011) |
| " We, therefore, investigated the analgesic effect of gabapentin, dexamethasone and low-dose ketamine in combination with paracetamol and ketorolac as compared with paracetamol and ketorolac alone after hip arthroplasty." | 2.75 | Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study. ( Christensen, BV; Dahl, JB; Dierking, G; Hilsted, KL; Larsen, TK; Mathiesen, O; Rasmussen, ML, 2010) |
| " Maxigesic tablets combine acetaminophen and ibuprofen in clinically appropriate doses to simplify administration and dosage regimen." | 2.75 | Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial. ( Anderson, BJ; Davies, E; Edwards, J; Frampton, C; Gibbs, RD; Merry, AF; Ting, GS, 2010) |
| "To determine the effectiveness of around-the-clock (ATC) analgesic administration, with or without nurse coaching, compared with standard care with as needed (PRN) dosing in children undergoing outpatient tonsillectomy." | 2.75 | A randomized clinical trial of the efficacy of scheduled dosing of acetaminophen and hydrocodone for the management of postoperative pain in children after tonsillectomy. ( Holdridge-Zeuner, D; Lanier, B; Mahoney, K; Miaskowski, C; Paul, SM; Savedra, MC; Sutters, KA; Waite, S, 2010) |
| "Pain, swelling, infection, trismus and temperature were recorded on days 3, 7 and 14 after surgery." | 2.75 | Antibiotic prophylaxis in third molar surgery: A randomized double-blind placebo-controlled clinical trial using split-mouth technique. ( Morkel, JA; Siddiqi, A; Zafar, S, 2010) |
| " Acetaminophen (as compared to placebo) in periodic doses starting at induction of anesthesia reduced the total dosage of oxycodone required over 0-24 h (P = 0." | 2.75 | The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy. ( Ahonen, J; Jokela, R; Korttila, K; Marjakangas, P; Seitsonen, E, 2010) |
| "We sought to study postoperative pain after endoscopic sinus surgery and to evaluate the efficacy of dexamethasone sodium phosphate in reducing pain and rescue analgesic requirements." | 2.75 | Role of dexamethasone in reducing pain after endoscopic sinus surgery in adults: a double-blind prospective randomized trial. ( Al-Qudah, M; Rashdan, Y, 2010) |
| " AEs were assessed at 8 hours after dosing in stage 1, at 72 hours after dosing in stage 2, and at the follow-up visit (7-10 days after surgery); in addition, patients were instructed to report any AE that occurred between scheduled assessments." | 2.75 | A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-control ( Aspley, S; Christensen, KS; Daniels, SE; Mehlisch, DR; Southerden, KA, 2010) |
| " dose of dexamethasone in combination with caudal block on postoperative analgesia in children." | 2.75 | Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy. ( Han, SW; Hong, JY; Kil, HK; Kim, EJ; Kim, WO, 2010) |
| "Acetaminophen has significant fentanyl-sparing effects and reduces side effects when combined with fentanyl in intravenous parent-/nurse-controlled analgesia for postoperative pediatric pain management." | 2.75 | Fentanyl-sparing effect of acetaminophen as a mixture of fentanyl in intravenous parent-/nurse-controlled analgesia after pediatric ureteroneocystostomy. ( Cho, JS; Hong, JY; Kil, HK; Kim, WO; Koo, BN; Suk, EH, 2010) |
| "Regarding its use as a unique drug for postoperative pain therapy, further comparative studies with higher doses of paracetamol are needed." | 2.75 | [Postoperative pain therapy after laparoscopic cholecystectomy: paracetamol versus diclofenac]. ( Dilber, E; Durak, P; Kılıç, M; Ozgök, A; Uzuner, A; Yağar, S, 2010) |
| "Of 200 consecutive breast cancer patients, 191 received the full package." | 2.75 | Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2010) |
| "The aim of this work was to evaluate the analgesic efficacy and safety of repeated doses of 2 dosing regimens of intravenous acetaminophen compared with placebo over 24 hours in subjects with moderate to severe pain after abdominal laparoscopic surgery." | 2.75 | A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery. ( Ang, RY; Breitmeyer, JB; Miller, H; Minkowitz, HS; Royal, MA; Singla, NK; Wininger, SJ, 2010) |
| " We investigated the analgesic effect of pregabalin and dexamethasone in combination with paracetamol after abdominal hysterectomy." | 2.74 | Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. ( Dahl, JB; Dierking, G; Fomsgaard, JS; Hilsted, KL; Lech, K; Lose, G; Mathiesen, O; Rasmussen, ML, 2009) |
| " Mild-to-moderate adverse effects were reported." | 2.74 | A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of paracetamol, serratiopeptidase, ibuprofen and betamethasone using the dental impaction pain model. ( Chopra, D; Kakkar, AK; Mehra, P; Rehan, HS, 2009) |
| "Postoperative pain was assessed during the first 8 hours and on the following day using the 101-point numeric rate scale (NRS-101) and the four-point verbal rating scale (VRS-4)." | 2.74 | The efficacy of acetaminophen-caffeine compared to Ibuprofen in the control of postoperative pain after periodontal surgery: a crossover pilot study. ( Rashwan, WA, 2009) |
| "The postoperative pain was assessed using visual analog scale (VAS) every 2 hours for the first 6 hours." | 2.74 | The prophylactic effect of rectal acetaminophen on postoperative pain and opioid requirements after adenotonsillectomy in children. ( Amini, S; Dashti, GA; Zanguee, E, 2009) |
| "Postoperative pain was evaluated and recovery characteristics were evaluated." | 2.74 | Evaluation of intravenous paracetamol administration on postoperative pain and recovery characteristics in patients undergoing laparoscopic cholecystectomy. ( Aytac, E; Demiroluk, S; Ertem, M; Karatas, A; Kaya, G; Salihoglu, Z; Yildirim, M, 2009) |
| " Additional measures included NPRS scores at predefined times over 48 hours, the summed pain intensity difference over 48 hours (SPID48), the time-weighted sum of pain relief scores over the first 8 hours, the mean dosing interval (the time from dosing to the time rescue medication or the next dose of study medication was administered, whichever was less), the proportion of patients requiring rescue medication, and the onset of perceptible and meaningful pain relief (2-stopwatch method)." | 2.74 | Diclofenac potassium liquid-filled soft gelatin capsules in the management of patients with postbunionectomy pain: a Phase III, multicenter, randomized, double-blind, placebo-controlled study conducted over 5 days. ( Boesing, SE; Diamond, E; Duckor, S; Gottlieb, I; Raymond, G; Riff, DS; Soulier, S, 2009) |
| "Ketamine has been shown to have a morphine-sparing effect soon after surgery." | 2.74 | The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study. ( Baud, A; Couvret, C; Favard, L; Fusciardi, J; Laffon, M; Le Tendre, C; Pourrat, X; Remérand, F, 2009) |
| "Morphine consumption was reduced, but this was not significant (p=0." | 2.74 | Placebo-controlled trial of local anaesthesia for treatment of pain after breast reconstruction. ( Beausang-Linder, M; Jurell, G; Legeby, M; Olofsson, C, 2009) |
| "Ibuprofen was consistently better than acetaminophen at 1 hour after treatment for relief of perineal pain after childbirth without any side effects." | 2.73 | Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial. ( Kamondetdecha, R; Tannirandorn, Y, 2008) |
| "Morphine consumption was not statistically significantly different between the groups (P>0." | 2.73 | Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements. ( Bakkal, K; Başar, H; Cakan, T; Culhaoglu, S; Inan, N, 2008) |
| " The limited efficacy of rofecoxib in this study contrasts to the results of previous surgical studies evaluating rofecoxib, and may be partially explained by the postoperative dosing in this arthroscopic surgical model." | 2.73 | The efficacy of rofecoxib 50 mg and hydrocodone/acetaminophen 7.5/750 mg in patients with post-arthroscopic pain. ( Chelly, JE; Nissen, CW; Rodgers, AJ; Smugar, SS; Tershakovec, AM, 2007) |
| "Postoperative pain was evaluated by visual analog scale, and it was measured at rest and during a deep breath." | 2.73 | Intravenous paracetamol as adjunctive treatment for postoperative pain after cardiac surgery: a double blind randomized controlled trial. ( Bacchi-Reggiani, L; Cattabriga, I; Di Bartolomeo, R; Grillone, G; Lamazza, G; Pacini, D; Talarico, F, 2007) |
| "To determine whether postoperative pain/distress in the early recovery period was different for those children who did or did not have local infiltration anaesthesia for extractions under general anaesthetic, and whether the incidence of clinically significant postoperative bleeding was different for the two groups." | 2.73 | Assessment of early postoperative pain and haemorrhage in young children undergoing dental extractions under general anaesthesia. ( McWilliams, PA; Rutherford, JS, 2007) |
| "Anaesthesia quality, postoperative pain and adverse events in a 24-hour period were evaluated." | 2.73 | Effects of reduction of the caudal morphine dose in paediatric circumcision on quality of postoperative analgesia and morphine-related side-effects. ( Alici, HA; Cesur, M; Erdem, AF; Silbir, F; Yapanoglu, T, 2007) |
| "Tramadol is reported to be an effective analgesic." | 2.73 | Peritonsillar infiltration with tramadol improves pediatric tonsillectomy pain. ( Atef, A; Fawaz, AA, 2008) |
| "On the second postoperative day, facial edema showed a statistically significant reduction in both dexamethasone 4-mg and dexamethasone 8-mg groups compared with the control group, but no statistically significant differences were observed between the 2 dosage regimens of dexamethasone." | 2.73 | Effect of submucosal injection of dexamethasone on postoperative discomfort after third molar surgery: a prospective study. ( Beretta, M; Borgonovo, A; Farronato, D; Garramone, RA; Grossi, GB; Maiorana, C; Santoro, F, 2007) |
| "Pre-treatment with fentanyl 1." | 2.73 | Administration of fentanyl before remifentanil-based anaesthesia has no influence on post-operative pain or analgesic consumption. ( Hoymork, SC; Lenz, H; Raeder, J, 2008) |
| "Postoperative pain was assessed regularly with the Children and Infants Postoperative Pain Scale score and rescue analgesia provided if scores were 4 or greater." | 2.73 | Randomized controlled trial of duration of analgesia following intravenous or rectal acetaminophen after adenotonsillectomy in children. ( Capici, F; Davidson, A; Fumagalli, R; Ingelmo, PM; Lorini, L; Milan, B; Sacchi, CA; Sperti, LR, 2008) |
| "To evaluate oral gabapentin for postoperative pain after photorefractive keratectomy (PRK)." | 2.73 | Oral gabapentin for the treatment of postoperative pain after photorefractive keratectomy. ( Babbar-Goel, A; Nissman, SA; Pasternak, JF; Tractenberg, RE, 2008) |
| "Midazolam was more frequently administered to patients receiving paracetamol suppositories, indicating that these children experienced more distress, possibly caused by pain." | 2.73 | Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery. ( Anderson, BJ; Mathot, RA; Prins, SA; Searle, S; Tibboel, D; Van Dijk, M; Van Leeuwen, P, 2008) |
| "Intravenous paracetamol resulted in a postoperative pain score of 0." | 2.72 | Intravenous versus oral paracetamol for postoperative analgesia: A systematic review. ( Stagg, K, 2021) |
| " The outcome measures of interest in the meta-analysis were ≥ 50% pain relief , need for rescue medications, and occurrence of adverse drug events." | 2.72 | Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis. ( Abushanab, D; Al-Badriyeh, D, 2021) |
| "Acetaminophen is a non-opioid analgesic commonly utilized for pain control after several types of surgical procedures." | 2.72 | Review of Intravenous Acetaminophen for Analgesia in the Postoperative Setting. ( Cohn, SM; DiPasquale, A; Segovia, M; Tompkins, DM, 2021) |
| "The primary outcome was 24-hour postoperative pain scores with movement as measured by the individual studies." | 2.72 | Perioperative intravenous acetaminophen and postcesarean pain control: a systematic review and meta-analysis of randomized controlled trials. ( Berghella, V; Felder, L; Quist-Nelson, J; Riegel, M, 2021) |
| "The studies evaluated patients' postoperative pain by either utilizing a visual analogue scale (VAS), measuring the time between surgery and when rescue analgesics were used, measuring the amount of rescue analgesics used, or by distributing questionnaires." | 2.72 | Pharmacological and Non-Pharmacological Methods of Postoperative Pain Control Following Oral and Maxillofacial Surgery: A Scoping Review. ( Elmowitz, JS; Shupak, RP, 2021) |
| " Adverse events occurred with the same frequency in the 3 treatment groups." | 2.72 | Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery. ( Hiesse-Provost, O; Jensen, TS; Juhl, GI; Norholt, SE; Tonnesen, E, 2006) |
| "Gabapentin-treated patients had less motor block when compared with control group." | 2.72 | Effect of oral gabapentin on postoperative epidural analgesia. ( Apfel, CC; Karamanlioglu, B; Kaya, G; Pamukçu, Z; Turan, A, 2006) |
| "Gabapentin has been suggested to decrease acute postoperative pain." | 2.72 | Gabapentin attenuates late but not acute pain after abdominal hysterectomy. ( Fassoulaki, A; Hassiakos, D; Petropoulos, G; Sarantopoulos, C; Siafaka, I; Stamatakis, E, 2006) |
| "Propacetamol is an injectable pro-drug of paracetamol (acetaminophen) with analgesic and antipyretic activities, especially used in the post-operative period." | 2.72 | Analgesic efficacy of parenteral paracetamol (propacetamol) and diclofenac in post-operative orthopaedic pain. ( Hiesse-Provost, O; Hynes, D; McCarroll, M, 2006) |
| "Morphine requirement was less in the combination than in the acetaminophen group both in the postanesthesia care unit (2." | 2.72 | The analgesic efficacy of acetaminophen, ketoprofen, or their combination for pediatric surgical patients having soft tissue or orthopedic procedures. ( Hiller, A; Korpela, R; Meretoja, OA; Piiparinen, S; Taivainen, T, 2006) |
| " Patient-controlled analgesia was used for the first 3 postoperative days in all patients, and the cumulative dosage used was recorded." | 2.72 | Analgesic effect of electroacupuncture in postthoracotomy pain: a prospective randomized trial. ( Chan, SK; Lee, TW; Liang, YM; Ng, CS; Sihoe, AD; Wan, IY; Wong, RH; Wong, WW; Yim, AP, 2006) |
| " The following medications were randomly given to the patients who declared pain in the sixth hour after the operation: naproxen sodium, meloxicam, rofecoxib, paracetamol, dipyrone, and etodolac in proper dosage to form groups of 20 for each medication." | 2.72 | [Postoperative pain management in clinics of otolaryngology]. ( Cağici, CA; Calişkan, EE; Erkan, AN; Gencay, S; Ozlüoğlu, LN; Sener, M; Yavuz, H; Yilmaz, I; Yilmazer, C, 2006) |
| "Postoperative pain was assessed at regular intervals for 24 h using All India Institute of Medical Sciences pain score." | 2.72 | Efficacy of three doses of tramadol with bupivacaine for caudal analgesia in paediatric inguinal herniotomy. ( Gogia, AR; Prakash, S; Singh, R; Tyagi, R, 2006) |
| "Postoperative pain was adequately controlled in those patients receiving suppositories when compared with those patients receiving oral pain medication." | 2.72 | Comparison of oral versus rectal administration of acetaminophen with codeine in postoperative pediatric adenotonsillectomy patients. ( Haddad, J; Owczarzak, V, 2006) |
| "The acetaminophen group was treated with antibiotics (amoxicillin-clavulonic acid), acetaminophen and placebo, acetaminophen-plus-honey group was treated with antibiotics (amoxicillin-clavulonic acid), acetaminophen, and honey." | 2.72 | Can postoperative pains following tonsillectomy be relieved by honey? A prospective, randomized, placebo controlled preliminary study. ( Elhan, AH; Genc, S; Ozlugedik, S; Tezer, M; Titiz, A; Unal, A, 2006) |
| "In addition to providing acute postoperative pain relief, preoperative PVB seems to reduce the prevalence of chronic pain 1 yr after breast cancer surgery." | 2.72 | Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery. ( Bachmann, MS; Kairaluoma, PM; Pere, PJ; Rosenberg, PH, 2006) |
| "Termination of pregnancy is a painful procedure." | 2.72 | Efficacy of suppository analgesia in postabortion pain reduction. ( Deutsch, M; Glik, A; Granot, M; Jakobi, P; Lowenstein, L; Tamir, A; Zimmer, EZ, 2006) |
| "ESS is associated with significant postoperative pain." | 2.72 | Acetaminophen is highly effective in pain treatment after endoscopic sinus surgery. ( Kemppainen, T; Kokki, H; Nuutinen, J; Seppä, J; Tuomilehto, H, 2006) |
| "Morphine requirements were decreased in the propacetamol group (21 vs 14." | 2.71 | Adjunctive analgesia with intravenous propacetamol does not reduce morphine-related adverse effects. ( Aubrun, F; Bellanger, A; Coriat, P; Kalfon, F; Langeron, O; Mottet, P; Riou, B, 2003) |
| " There were no significant differences between treatment groups with respect to the number of patients requiring rescue medication, however the time to dosing was significantly longer for those taking soluble aspirin when compared with placebo (hazard ratio 2." | 2.71 | An investigation into the comparative efficacy of soluble aspirin and solid paracetamol in postoperative pain after third molar surgery. ( Hawkesford, JE; Hill, CM; Seymour, RA; Stillings, M; Sykes, J, 2003) |
| "Alfentanil was available via patient-controlled analgesia (PCA) during the 4-h postoperative study period." | 2.71 | Analgesic effect of i.v. paracetamol: possible ceiling effect of paracetamol in postoperative pain. ( Hahn, TW; Hjortsoe, NC; Jacobsen, LS; Lund, C; Mogensen, T; Rasmussen, M; Rasmussen, SN, 2003) |
| "Ketoprofen was a more effective analgesic than acetaminophen on the day of surgery (SUMPI3." | 2.71 | Ketoprofen 75 mg qid versus acetaminophen 1000 mg qid for 3 days on swelling, pain, and other postoperative events after third-molar surgery. ( Bjørnsson, GA; Haanaes, HR; Skoglund, LA, 2003) |
| "Rofecoxib was also more effective than celecoxib in reducing pain and improving patient satisfaction after otolaryngologic surgery." | 2.71 | Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. ( Issioui, T; Klein, KW; Watcha, MF; White, PF, 2003) |
| "I." | 2.71 | Randomized, double-blind, placebo-controlled study of the effect of rectal paracetamol on morphine consumption after abdominal hysterectomy. ( Borchgrevink, PC; Dale, O; Hagen, L; Kvalsvik, O, 2003) |
| "6 l/h/70 kg with a maturation half-life of 8." | 2.71 | Paracetamol and metabolite pharmacokinetics in infants. ( Anderson, BJ; Holford, NH; Jansman, FG; Pluim, MA; Tibboel, D; van den Anker, JN; van der Marel, CD; van Lingen, RA, 2003) |
| "The intensity change of postoperative pain was then evaluated 10 times with visual analog scale and verbal describing scale during 6 h from the beginning of propacetamol infusion." | 2.71 | [A randomized, double blind, and controlled clinical trial of the non-addictive propacetamol in postoperative analgesia]. ( Cui, Y; Jiang, ZM; Liu, J; Ma, EL; Wang, R; Wang, XR, 2003) |
| "Ketoprofen lysine was more effective than paracetamol in reducing postoperative pain (P = 0." | 2.71 | Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial. ( Busoni, P; Fedele, G; Gallini, C; Grossetti, R; Ivani, G; Maestri, L; Messeri, A; Murolo, S; Noccioli, B; Novellini, R, 2003) |
| "Naproxen was statistically superior (p < or = 0." | 2.71 | Naproxen 500 mg bid versus acetaminophen 1000 mg qid: effect on swelling and other acute postoperative events after bilateral third molar surgery. ( Bjørnsson, GA; Haanaes, HR; Skoglund, LA, 2003) |
| "5 mg) vs paracetamol (500 mg) and placebo given in a flexible dosage regimen to treat pain resulting from extraction of impacted third molar teeth." | 2.71 | Analgesic efficacy of low-dose diclofenac versus paracetamol and placebo in postoperative dental pain. ( Gold, MS; Ionescu, E; Kubitzek, F; Liu, JM; Ziegler, G, 2003) |
| "Trismus was determined by measuring maximum interincisal opening and facial swelling was evaluated using a tape measuring method." | 2.71 | Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery. ( Erdogan, O; Esen, E; Karsli, ED; UStün, Y, 2003) |
| "Propacetamol and morphine were significantly more effective than placebo in all primary measures of analgesia over 5 h after the first administration and globally over 10 h (first and second administrations)." | 2.71 | Assessing analgesia in single and repeated administrations of propacetamol for postoperative pain: comparison with morphine after dental surgery. ( Buerkle, H; Thys, L; Van Aken, H; Veekman, L, 2004) |
| "Tramadol plus APAP was superior to placebo for total pain relief, sum of pain intensity differences, and sum of pain relief and pain intensity differences (P < or =0." | 2.71 | Combination tramadol plus acetaminophen for postsurgical pain. ( Jordan, D; Kamin, M; Ravikumar, TS; Rosenthal, N; Smith, AB; Xiang, J, 2004) |
| "Tramadol/APAP was superior to tramadol (P < 0." | 2.71 | A double-blind placebo-controlled comparison of tramadol/acetaminophen and tramadol in patients with postoperative dental pain. ( Fisher, A; Fricke, JR; Hewitt, DJ; Jordan, DM; Rosenthal, NR, 2004) |
| "Rofecoxib was associated with a significantly lower incidence of nausea (18." | 2.71 | Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: a randomized, double-blind, placebo-controlled study in patients with moderate to severe postoperative pain in the third molar extraction model. ( Fricke, JR; Korn, S; Kotey, PN; Vassil, TC, 2004) |
| " ATC) dosing of acetaminophen with codeine, with or without nurse coaching, compared to standard care with as needed (i." | 2.71 | A randomized clinical trial of the effectiveness of a scheduled oral analgesic dosing regimen for the management of postoperative pain in children following tonsillectomy. ( Holdridge-Zeuner, D; Lanier, B; Miaskowski, C; Paul, SM; Savedra, MC; Sutters, KA; Waite, S, 2004) |
| "The difference in postoperative pain was assessed by four primary end-points: pain intensity as measured by a 100-mm visual analogue scale hourly for 12 h, median time to rescue analgesic, postoperative acetaminophen consumption, and patient's global assessment." | 2.71 | Preoperative intravenous tramadol versus ketorolac for preventing postoperative pain after third molar surgery. ( Ong, KS; Tan, JM, 2004) |
| " Mean total pain relief and the sum of pain intensity difference were also similar in the early period after dosing (0-4 hours)." | 2.71 | Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model. ( Cha, IH; Jung, YS; Kim, DK; Kim, HJ; Kim, MK; Lee, EW, 2004) |
| " Postoperatively the propacetamol dosage was repeated twice and diclofenac once on the ward." | 2.71 | Propacetamol and diclofenac alone and in combination for analgesia after elective tonsillectomy. ( Hiller, A; Savolainen, S; Silvanto, M; Tarkkila, P, 2004) |
| "5 mg/kg of the study drug was injected and this dosage was added to the total amount." | 2.71 | The postoperative analgesic effect of tramadol when used as subcutaneous local anesthetic. ( Altunkaya, H; Babuccu, O; Demirel, CB; Hosnuter, M; Kargi, E; Ozer, Y; Ozkocak, I, 2004) |
| "The severity of the postoperative pain was evaluated by a visual pain scale (VAS) (0-100), side-effects such as vomiting and postoperative haemorrhage were documented." | 2.71 | [Postoperative pain therapy after tonsillectomy in children. An observational study for 7 days]. ( Ebeling, O; Fösel, T; Fötsch, S, 2005) |
| "The difference in postoperative pain between pretreated and post-treated side in each patient was assessed by four primary end-points: pain intensity as measured by a 100-mm visual analogue scale hourly for 12 h, time to rescue analgesic, postoperative analgesic consumption, and patient's global assessment." | 2.71 | Preoperative ketorolac has a preemptive effect for postoperative third molar surgical pain. ( Chen, FG; Ho, VC; Ong, KS; Seymour, RA, 2004) |
| "Diclofenac was repeated after 18 hours and paracetamol every 6 hours for 24 hours; diclofenac: diclofenac as in diclofenac/paracetamol, with placebos replacing paracetamol; and placebo: 2 placebo suppositories at same times as diclofenac/paracetamol." | 2.71 | Opioid-sparing effects of diclofenac and paracetamol lead to improved outcomes after cardiac surgery. ( Abel, RJ; Djaiani, G; Fayaz, MK; Hall, JE; Mecklenburgh, JS; Pugh, SC, 2004) |
| " Fentanyl (in post-anesthesia care unit) and paracetamol (at home) were supplementary analgesics and the dosage was also recorded." | 2.71 | [Comparison of preemptive analgesia efficacy between etoricoxib and rofecoxib in ambulatory gynecological surgery]. ( Liu, W; Loo, CC; Ren, HZ; Tan, HM; Ye, TH, 2004) |
| " Safety was monitored through adverse event reporting, clinical examination, and laboratory testing." | 2.71 | Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery. ( Groudine, SB; Jahr, JS; Payen-Champenois, C; Reynolds, LW; Sinatra, RS; Viscusi, ER, 2005) |
| "Within the first 12 h after inguinal hernia repair in adult patients, a single injection of parecoxib 40 mg compares favorably with 2 injections of propacetamol 2 g." | 2.71 | A randomized, double-blind comparison between parecoxib sodium and propacetamol for parenteral postoperative analgesia after inguinal hernia repair in adult patients. ( Baechle, JP; Beaussier, M; Buffin, A; Didelot, JP; Goater, P; Lavazais, S; Lienhart, A; Loriferne, JF; Mosbah, A; Paugam, C; Perier, JF; Said, R; Weickmans, H, 2005) |
| " The primary outcome measures were total pain relief through 6 hours after dosing (TOTPAR6), sum of pain intensity differences through 6 hours (SPID6), and adverse events." | 2.71 | Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: a randomized, double-blin ( Adamson, DN; Christensen, SE; Han, SH; Litkowski, LJ; Newman, KB; Van Dyke, T, 2005) |
| " Each side effect was recoded into a dichotomous response (i." | 2.71 | Time-contingent dosing of an opioid analgesic after tonsillectomy does not increase moderate-to-severe side effects in children. ( Holdridge-Zeuner, D; Lanier, B; Miaskowski, C; Paul, SM; Savedra, MC; Sutters, KA; Waite, S, 2005) |
| " However, it should be noted that there is a difference in the bioavailability between the 2 formulations of up to 30%, which may explain the findings." | 2.71 | The analgesic efficacy of intravenous versus oral tramadol for preventing postoperative pain after third molar surgery. ( Lirk, P; Ong, CK; Sow, BW; Tan, JM, 2005) |
| "Incidence of postoperative nausea and vomiting (PONV) was noted." | 2.71 | Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting. ( Jakobsson, J; Owall, A; Pettersson, PH, 2005) |
| " The present prospective, placebo-controlled and double-blind study aimed to evaluate the analgesic efficacy of diclofenac, a non-steroid anti-inflammatory drug (NSAID), in combination with paracetamol and opioids." | 2.71 | Analgesic efficacy of diclofenac in combination with morphine and paracetamol after mastectomy and immediate breast reconstruction. ( Legeby, M; Olofsson, C; Sandelin, K; Wickman, M, 2005) |
| "Rofecoxib was statistically significantly superior to codeine/acetaminophen with respect to TOPAR4, patient global assessment, peak pain relief, and duration of analgesic effect." | 2.71 | Analgesic efficacy of rofecoxib compared with codeine/acetaminophen using a model of acute dental pain. ( Bird, SR; Bohidar, NR; Chang, DJ; King, T, 2005) |
| "Effective and early treatment of postoperative pain and nausea have become pivotal for the early discharge of patients after tonsillectomy." | 2.71 | A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults. ( Ammar, MM; Gilbert, JG; Khrapov, AV; McClintock, A; Naesh, O; Niles, LA; Phibbs, PW; Phillips, AM; Robert, AJ, 2005) |
| "The prevalence of unrelieved postoperative pain is high and may lead to adverse effects including prolonged hospitalization and delayed recovery." | 2.71 | The effect of music therapy on postoperative pain, heart rate, systolic blood pressures and analgesic use following nasal surgery. ( Benzie, IF; Chan, MF; Tse, MM, 2005) |
| "To assess clinical efficacy of IV paracetamol 1 g and IV metamizol 1 IV metamizol 1 g on a 24-h dosing schedule in this randomized, double-blinded, placebo-controlled study of 38 ASA physical status I-III patients undergoing retinal surgery." | 2.71 | A comparison between IV paracetamol and IV metamizol for postoperative analgesia after retinal surgery. ( Eggert, D; Giesecke, T; Kampe, S; Kiencke, P; Landwehr, S; Thumann, G, 2005) |
| "Optimizing postoperative pain control is an important aspect in perioperative patient care." | 2.71 | Pre-incision infiltration of local anesthetic reduces postoperative pain with no effects on bruising and wound cosmesis after thyroid surgery. ( Bagul, A; Brook, NR; Metcalfe, MS; Nicholson, ML; Taha, R, 2005) |
| "Finally, patient satisfaction with postoperative pain control was significantly higher in the FT group." | 2.71 | Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. ( Cadeddu, JA; Duchene, D; Johnson, DB; Recart, A; Thomas, T; White, PF, 2005) |
| "Tramadol/APAP was superior to placebo for the following outcome variables: total pain relief (TOTPAR, P = ." | 2.71 | Tramadol/acetaminophen tablets in the treatment of postsurgical orthopedic pain. ( Bourne, MH; Jordan, D; Kamin, M; Rosenthal, NR; Xiang, J, 2005) |
| "Propacetamol did not enhance analgesia, nor did it decrease cumulative opioid consumption or reduce adverse effects in a dose of 2 g given every sixth hour for 3 days after surgery." | 2.70 | Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery. ( Hakala, T; Hendolin, H; Hynynen, M; Kokki, H; Lahtinen, P, 2002) |
| "Suppression of postoperative pain immediately after surgery attenuates the pain experienced 1 to 2 days after surgery." | 2.70 | Attenuation of pain in a randomized trial by suppression of peripheral nociceptive activity in the immediate postoperative period. ( Brahim, JS; Dionne, RA; Dubner, R; Gordon, SM; McCullagh, LM; Sang, C, 2002) |
| "Tramadol was the most effective analgesic, as evidenced by low pain scores, least rescue medication, and fewest number of patients with sleep disturbance." | 2.70 | Postoperative analgesia at home after ambulatory hand surgery: a controlled comparison of tramadol, metamizol, and paracetamol. ( Allvin, R; Amilon, A; Hallén, J; Ohlsson, T; Rawal, N, 2001) |
| " Mean Cmax was 2." | 2.70 | Pharmacokinetics of oral diclofenac and acetaminophen in children after surgery. ( Drozdziewicz, D; Ostergaard, D; Ravn, G; Rømsing, J; Senderovitz, T; Sonne, J, 2001) |
| "The Ketoprofen group had lower numerical rating scale (P < 0." | 2.70 | Intravenous ketoprofen in thyroid and parathyroid surgery. ( Basto, ER; Eurin, BG; Jacob, LP; Landru, JP; Mourey, FD; Waintrop, C, 2001) |
| "5 hours) after dosing (P < or = 0." | 2.70 | Efficacy and tolerability of celecoxib versus hydrocodone/acetaminophen in the treatment of pain after ambulatory orthopedic surgery in adults. ( Brugger, A; Geis, GS; Gimbel, JS; Verburg, KM; Zhao, W, 2001) |
| "Propacetamol was not significantly different from ketorolac 15 mg and 30 mg with respect to the main analgesic efficacy variables during the 6-h assessment period." | 2.70 | Propacetamol versus ketorolac for treatment of acute postoperative pain after total hip or knee replacement. ( Tang, J; White, PF; Zhou, TJ, 2001) |
| " Adverse effects were comparable in the three groups, except for significantly more nausea in the control group (39% vs." | 2.70 | Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection. ( Fletcher, D; Gillon, MC; Incagnoli, P; Josse, C; Kuhlman, L; Mimoz, O; Mirand, A; Soilleux, H, 2001) |
| "Ibuprofen is a peripherally acting nonsteroidal anti-inflammatory drug indicated fo ranalgesia, antipyresis, and various arthritic conditions." | 2.70 | Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain. ( Cooper, S; Doyle, G; Jayawardena, S; Marrero, I; Olson, NZ; Otero, AM; Sunshine, A; Tirado, S, 2001) |
| "Postoperative pain was assessed in the fully awake patient after extubation (hour 0) and at 1, 2, 4, 8, and 24 hours using a visual analog scale (VAS)." | 2.70 | Postoperative pain management after supratentorial craniotomy. ( Grenier, B; Maurette, P; Mesli, A; Sesay, M; Siao, D; Verchère, E, 2002) |
| "Postoperative pain was assessed by a blinded observer using the CHEOPS score on eye-opening, and then at 10, 30 and 60 minutes." | 2.70 | Diclofenac or paracetamol for analgesia in paediatric myringotomy outpatients. ( Tan, S; Tay, CL, 2002) |
| "Valdecoxib has a tolerability profile superior to that of oxycodone/acetaminophen." | 2.70 | The analgesic efficacy of valdecoxib vs. oxycodone/acetaminophen after oral surgery. ( Daniels, SE; Desjardins, PJ; Recker, DP; Talwalker, S; Verburg, KM, 2002) |
| "2 cases from the morphine group." | 2.69 | [Comparison of propacetamol and morphine in postoperative analgesia]. ( Biollaz, J; Buclin, T; Vuilleumier, PA, 1998) |
| "Morphine was administered by a patient-controlled analgesia (PCA) device." | 2.69 | Efficacy of propacetamol in the treatment of postoperative pain. Morphine-sparing effect in orthopedic surgery. Italian Collaborative Group on Propacetamol. ( Ballabio, M; Peduto, VA; Stefanini, S, 1998) |
| " There were no serious adverse events observed in this study, with the overall incidence of side effects being somewhat less in the (R)- ketoprofen groups than in the acetaminophen 1,000 mg group." | 2.69 | Analgesic efficacy and safety of (R)- ketoprofen in postoperative dental pain. ( Cooper, SA; Hersh, EV; Reynolds, B; Reynolds, DC, 1998) |
| "We have examined acetaminophen (paracetamol) dosing for outpatient management of posttonsillectomy pain in children." | 2.69 | Examination of acetaminophen for outpatient management of postoperative pain in children. ( Harder, A; Hertel, S; Rasmussen, M; Rømsing, J, 1998) |
| "Postoperative pain was assessed by self-report 1." | 2.69 | Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy. ( Ostergaard, D; Rømsing, J; Valentin, N; Walther-Larsen, S, 1998) |
| "The acetaminophen group had lower pain scores on Day 1 (2." | 2.69 | Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain. ( Fox, L; McGuinnety, M; Schug, SA; Sidebotham, DA; Thomas, J, 1998) |
| "To determine the relative bioavailability and plasma paracetamol concentration profiles following administration of a proprietary formulation of paracetamol suppositories to postoperative children." | 2.69 | Relative bioavailability and plasma paracetamol profiles of Panadol suppositories in children. ( Coulthard, KP; Covino, A; Matthews, NT; Murray, RS; Nielson, HW; Schroder, M; Van Der Walt, JH, 1998) |
| "Acetaminophen with codeine was more effective in controlling pain on days 1 and 3 (p = 0." | 2.69 | Ibuprofen for tonsillectomy pain in children: efficacy and complications. ( Dattolo, RA; Harley, EH, 1998) |
| "morphine was administered along with oral hydrocodone/acetaminophen and other medications commonly administered after cesarean delivery." | 2.69 | Determination of an effective dose of intrathecal morphine for pain relief after cesarean delivery. ( Eisenach, J; Floyd, H; Gerancher, JC, 1999) |
| "Oral clonidine is an effective analgesic and sedative for children undergoing tonsillectomy or adenotonsillectomy." | 2.69 | The effectiveness of clonidine as an analgesic in paediatric adenotonsillectomy. ( Dunn, GS; Merrick, PM; Montgomery, CJ; Reimer, EJ; Sanderson, PM; Scheepers, LD, 1998) |
| "Propacetamol and ketorolac, combined with patient-controlled analgesia morphine, show similar analgesic efficacy after gynecologic surgery." | 2.69 | A double-blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: analgesic efficacy and tolerability after gynecologic surgery. ( Agrò, F; Aloe, L; Ballabio, M; De Cillis, P; De Nicola, A; Giunta, F; Ischia, S; Marinangeli, F; Stefanini, S; Varrassi, G, 1999) |
| "Postoperative pain was assessed by VAS score." | 2.69 | Paracetamol 1 g given rectally at the end of minor gynaecological surgery is not efficacious in reducing postoperative pain. ( Hein, A; Jakobsson, J; Ryberg, G, 1999) |
| "Postoperative pain is a major problem in day-case surgery in children." | 2.69 | Morphine-sparing effect of acetaminophen in pediatric day-case surgery. ( Korpela, R; Korvenoja, P; Meretoja, OA, 1999) |
| " The equipotent morphine dosage requirements were also not statistically different." | 2.69 | Patient-controlled analgesia in postoperative cardiac surgery. ( Brush, B; Tsang, J, 1999) |
| " The time-concentration profiles for each individual were used to estimate pharmacokinetic parameters using a non-linear mixed effects model (NONMEM)." | 2.69 | Pharmacokinetics of paracetamol in adults after cardiac surgery. ( Anderson, BJ; Holford, NH; Schuitmaker, M; Woollard, GA, 1999) |
| "Postoperative pain was assessed by means of a modified Objective Pain Score and analgesia was administered if this score exceeded four." | 2.69 | The effect of ketamine on 0.25% and 0.125% bupivacaine for caudal epidural blockade in children. ( Aldridge, LM; Doyle, E; Findlow, D; Johnston, P, 1999) |
| "Postoperative pain was assessed by self-report each day before scheduled medication at 7 h, 12 h, 18 h and 23 h." | 2.69 | Diclofenac or acetaminophen for analgesia in paediatric tonsillectomy outpatients. ( Drozdziewicz, D; Ostergaard, D; Ravn, G; Rømsing, J; Schultz, P, 2000) |
| "Fentanyl was the intraoperative analgesic and postoperative rescue analgesia was paracetamol, diclofenac and intramuscular codeine." | 2.69 | A comparison of rectal and intramuscular codeine phosphate in children following neurosurgery. ( Andrews, KA; Hack, HA; Jenkins, AM; Llewelyn, N; MacKersie, A; May, L; McEwan, A; Sigston, PE, 2000) |
| "Most of the patients experienced little postoperative pain with more than 70% scoring less than 20 mm on a VAS-scale from 0-100 mm at any time during the postoperative period." | 2.69 | No effect of preoperative paracetamol and codeine suppositories for pain after termination of pregnancies in general anaesthesia. ( Dahl, V; Fjellanger, F; Raeder, JC, 2000) |
| "Tramadol is a weak centrally acting analgesic and it might provide efficacious postoperative pain relief with minimal sedative effects in the use of intravenous patient-controlled analgesia (PCA)." | 2.69 | Comparison of intravenous patient-controlled analgesia with tramadol versus morphine after microvascular breast reconstruction. ( Pitkänen, M; Rosenberg, PH; Silvasti, M; Svartling, N, 2000) |
| "Subsidiary outcome measures were postoperative pain score, sedative and analgesic requirements before and during surgery, and postoperative analgesic requirements." | 2.69 | A comparison of superficial versus combined (superficial and deep) cervical plexus block for carotid endarterectomy: a prospective, randomized study. ( Bree, S; Crider, B; Dillon, P; Elcock, D; McLaren, ID; Pandit, JJ, 2000) |
| " This dosage of paracetamol is lower than the current recommended dosage, which is 40 mg kg(-1) loading dose followed by 20 mg kg(-1) 8 h(-1)." | 2.69 | Double-blind randomized study of tramadol vs. paracetamol in analgesia after day-case tonsillectomy in children. ( Dort, JP; Pendeville, PE; Veyckemans, F; Von Montigny, S, 2000) |
| "Ibuprofen was apparently adequate in controlling pain for 147 out of 161 patients but on further questioning 42 of these patients took supplemental analgesics and self-prescribed paracetamol or a paracetamol combination." | 2.69 | Pain control after routine dento-alveolar day surgery: a patient satisfaction survey. ( Joshi, A; Rood, JP; Snowdon, AT; Worthington, HV, 2000) |
| "Need to improve the efficiency of postoperative pain management by early switching from intravenous to oral acetaminophen." | 2.69 | Effect of multifaceted intervention promoting early switch from intravenous to oral acetaminophen for postoperative pain: controlled, prospective, before and after study. ( Auleley, GR; Conort, O; Durieux, P; Hazebroucq, G; Lamas, JP; Ripouteau, C, 2000) |
| "Ibuprofen liquigel is a solubilized potassium ibuprofen 200-mg gelatin capsule formulation that was approved for over-the-counter use in 1995." | 2.69 | Ibuprofen liquigel for oral surgery pain. ( Cooper, SA; Doyle, G; Hersh, EV; Hong, D; Levin, LM; Secreto, SA; Waksman, J; Wedell, D, 2000) |
| "Tramadol hydrochloride is a synthetic mu-opioid agonist with additional monoaminergic activity." | 2.68 | Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison. ( Breivik, H; Grimstad, J; Stubhaug, A, 1995) |
| "After umbilical hernia surgery, and wound infiltration with bupivacaine 0." | 2.68 | The effect of ketorolac as an adjuvant to local anaesthetic infiltration for analgesia in paediatric umbilical hernia surgery. ( Graham, SG; Wandless, JG, 1995) |
| " Peak concentration occurred (Tmax) at 2." | 2.68 | Pharmacokinetics of rectal paracetamol after major surgery in children. ( Anderson, BJ; Holford, NH; Woolard, GA, 1995) |
| "Postoperative pain was assessed with mCHEOPS in the anaesthesia recovery room, with postoperative usage of opioid and acetaminophen in the hospital, and with parental assessment of pain with a VAS." | 2.68 | Regional anaesthesia for hernia repair in children: local vs caudal anaesthesia. ( Bass, J; Komocar, L; Splinter, WM, 1995) |
| "Propacetamol doses were statistically higher in the S group than in the D group (7." | 2.68 | [Efficacy of propacetamol in postoperative pain based on two modes of intravenous administration]. ( Farhat, F; Jayr, C; Savoyen, MC, 1995) |
| "Buprenorphine requirements were decreased to 56% and 37% in groups 2 and 3 respectively, compared to group 1 (P < 0." | 2.68 | [Comparative study of buprenorphine and its combination to ketoprofen or propacetamol for postoperative analgesia in urologic surgery]. ( Delort-Laval, S; Guenard, Y; Krol-Houdek, MC; Maurette, P; Muscagorry, JM; Tauzin-Fin, P, 1996) |
| "Both ketoprofen treatments and patients treated with paracetamol 1000 mg reported significantly greater pain relief (P < 0." | 2.68 | The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery. ( Hawkesford, JE; Kelly, PJ; Seymour, RA, 1996) |
| "Morphine consumption was greatest in the group that received paracetamol alone and lowest in the group given the combination (P < 0." | 2.68 | Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination. ( Kestin, IG; Montgomery, JE; Sneyd, JR; Sutherland, CJ, 1996) |
| "Postoperative pain was assessed with a verbal pain scale and a visual analog scale (VAS) at rest and during movement and cough, 1, 2, 4, 6, and 24 h postoperatively." | 2.68 | Comparison of tenoxicam by intramuscular injection or wound infiltration for analgesia after inguinal herniorrhaphy. ( Dahl, JB; Friis, E; Knudsen, KE; Kristensen, BB; Linnemann, MU; Mikkelsen, SS, 1996) |
| "0 ml, dosage 1." | 2.68 | Comparison of the efficacy of paracetamol versus paracetamol, codeine and promethazine (Painstop) for premedication and analgesia for myringotomy in children. ( Davidson, A; Ragg, P, 1997) |
| "Postoperative pain is a significant problem that continues to be undertreated in the pediatric population." | 2.68 | Effect of preemptive acetaminophen on postoperative pain scores and oral fluid intake in pediatric tonsillectomy patients. ( Merkel, SI; Quinn, P; Reynolds, PI; Romej, M; Voepel-Lewis, T, 1996) |
| "05) were observed between efficacy measures and the various pharmacokinetic parameters (AUC0-300, Cmax and Tmax) for ibuprofen after the soluble dose." | 2.68 | Are the pharmacokinetics of ibuprofen important determinants for the drug's efficacy in postoperative pain after third molar surgery? ( Hawkesford, JE; Jones, K; Seymour, RA, 1997) |
| "Postoperative pain was assessed using the Children's Hospital of Eastern Ontario Pain Scale (CHEOPS) upon arrival to the PACU and at 5, 10, 15, 30, 45, and 60 min." | 2.68 | Postoperative analgesia with preoperative oral ibuprofen or acetaminophen in children undergoing myringotomy. ( Allen, H; Bennie, RE; Boehringer, LA; Dierdorf, SF; McMahon, S, 1997) |
| "Propacetamol was statistically superior to placebo on all assessment criteria." | 2.68 | The analgesic efficacy of an injectable prodrug of acetaminophen in children after orthopaedic surgery. ( Berniere, J; Boccard, E; Granry, JC; Jean, N; Merckx, J; Monrigal, JP; Rod, B, 1997) |
| "Postoperative pain was assessed by means of a modified Objective Pain Score and analgesia was administered if this exceeded a value of 4." | 2.68 | Comparison of caudal block using bupivacaine and ketamine with ilioinguinal nerve block for orchidopexy in children. ( Aldridge, LM; Doyle, E; Findlow, D, 1997) |
| " The population was divided into two groups: group 1 received 20 mg of nalbuphine hydrochloride and group 2 received 2 g of propacetamol combined with 10 mg of nalbuphine hydrochloride." | 2.67 | [Comparison of the analgesic efficacy of nalbuphine and its combination with propacetamol during the immediate postoperative period in gynecologic-obstetric surgery]. ( Granry, JC; Jacob, JP; Monrigal, C, 1994) |
| "Postoperative pain was rated on a paediatric pain scale." | 2.67 | Pre-emptive analgesia: comparison of preoperative with postoperative caudal block on postoperative pain in children. ( Eichwede, F; Holthusen, H; Lipfert, P; Stevens, M; Willnow, U, 1994) |
| "Late postoperative pain, fatigue and conservative attitudes and routines in the postoperative care, were the most important reasons limiting mobilization and activity." | 2.67 | The effect of balanced analgesia on early convalescence after major orthopaedic surgery. ( Dahl, JB; Gebuhr, P; Hansen, BL; Hjortsø, NC; Kehlet, H; Møiniche, S; Rosenberg, J, 1994) |
| "There were no major intraoperative complications in either group." | 2.67 | Laparoscopic versus open appendicectomy: prospective randomised trial. ( Chung, SC; Dawson, JW; Lau, WY; Li, AK; Tate, JJ, 1993) |
| "There is a trend toward reduced postoperative pain in the acetaminophen pretreatment groups." | 2.67 | The efficacy of preoperative analgesic administration for postoperative pain management of pediatric dental patients. ( Antony, SJ; Courts, FJ; Primosch, RE, 1993) |
| "Ketoprofen (Orudis) is a nonsteroidal anti-inflammatory drug that is currently approved in the United States for the management of mild to moderate pain." | 2.67 | Ketoprofen, acetaminophen plus oxycodone, and acetaminophen in the relief of postoperative pain. ( De Castro, A; Olson, NZ; Sunshine, A; Zighelboim, I, 1993) |
| "Acute postoperative pain is a common experience in oral surgery practice." | 2.67 | [Analgesic efficacy and the tolerance for piroxicam-beta-cyclodextrin compared to piroxicam, paracetamol and placebo in the treatment of postextraction dental pain]. ( Dolci, G; Pacifici, L; Ripari, M; Umile, A, 1993) |
| "Postoperative pain was reported in 35% of patients, with no significant difference between treated and control patients." | 2.67 | Prophylactic paracetamol for analgesia after vaginal termination of pregnancy. ( Ashley, J; Cade, L, 1993) |
| "Tramadol hydrochloride is a synthetic opiate agonist with a plasma elimination half-life of 5 to 6 hours and peak plasma levels at about 1 1/2 hours." | 2.67 | Analgesic oral efficacy of tramadol hydrochloride in postoperative pain. ( DeCastro, A; Minn, FL; Olson, NZ; Sunshine, A; Zighelboim, I, 1992) |
| "Ibuprofen was more effective after one hour than either of the other two drugs, whatever the scale or parameter used." | 2.67 | [Analgesic effect of ibuprofen in pain after episiotomy]. ( Barrat, J; Behotas, S; Boureau, F; Castiel, J; Chauvin, A; Lienhart, A; Martin, A, 1992) |
| "The profiles of postoperative pain in the two groups were similar from the first postoperative day, but Ibumetin was better pain reliever on the day of surgery." | 2.67 | Pain control after third molar surgery--a comparative study of ibuprofen (Ibumetin) and a paracetamol/codeine combination (Citodon). ( Anzén, B; Lysell, L, 1992) |
| " This trial design (crossover with multiple dosing in outpatients) is a sensitive way of testing for analgesia, and is potentially more predictive of adverse effect problems than single-dose studies." | 2.67 | A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery. ( Carroll, D; Guest, P; Juniper, RP; McQuay, HJ; Moore, RA, 1992) |
| "In a double-blind, placebo-controlled study in 125 patients undergoing a cholecystectomy, a comparison was made of the quality of post-operative pain relief during 'patient-controlled' intake of sublingual buprenorphine in combination with either rectally administered naproxen 1000 mg/24 h, paracetamol 4000 mg/24 h or a placebo." | 2.67 | Application of sublingual buprenorphine in combination with naproxen or paracetamol for post-operative pain relief in cholecystectomy patients in a double-blind study. ( Crul, BJ; Joosten, HJ; Vollaard, EJ; von Egmond, J; Witjes, WP, 1992) |
| " Flurbiprofen in 50 mg and 100 mg dosages demonstrated effective analgesic activity with the 100 mg dosage being at least as effective as the acetaminophen/codeine combination." | 2.67 | The analgesic efficacy of flurbiprofen compared to acetaminophen with codeine. ( Cooper, SA; Kupperman, A, 1991) |
| "Two-hundred six outpatients with postoperative pain after the surgical removal of impacted third molars were randomly assigned on a double-blind basis to receive oral doses of ketorolac tromethamine 10 and 20 mg, ibuprofen 400 mg, acetaminophen 600 mg, a combination of acetaminophen 600 mg plus codeine 60 mg, or placebo." | 2.67 | Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain. ( Beaver, WT; Forbes, JA; Grodin, CD; Kehm, CJ, 1990) |
| "Ibuprofen has important implications for postoperative pain in clinical practice." | 2.67 | Multicenter clinical trial of ibuprofen and acetaminophen in the treatment of postoperative dental pain. ( Helfrick, JF; Leibold, DG; Markowitz, R; Mehlisch, DR; Schow, CE; Shultz, R; Sollecito, WA; Waite, DE, 1990) |
| " Both plasma elimination half life and area under the plasma concentration time curve were significantly increased in neonates after suppository dosing compared with older children." | 2.67 | Pharmacokinetics of paracetamol after cardiac surgery. ( Booker, PD; Hopkins, CS; Underhill, S, 1990) |
| "Flurbiprofen was shown to possess an adequate analgesic effect superior to either placebo (P less than 0." | 2.67 | Analgesic efficacy of flurbiprofen as compared to acetaminophen and placebo after periodontal surgery. ( Gallardo, F; Rossi, E, 1990) |
| "Ibuprofen was found to be the most effective analgesic in post-episiotomy pain followed by analgin and paracetamol in that order." | 2.67 | A comparison of four analgesics in post-episiotomy pain. ( Agshikar, NV; Bhounsule, SA; Dhume, VG; Nevreker, PR; Pal, MN, 1990) |
| "It is essential to find good postoperative pain control strategies that facilitate early mobility, early recovery, and early hospital discharge with minimal side effects on the mother and infant." | 2.66 | Strategies of analgesic treatment after cesarean delivery. Current state and new alternatives. ( Arroyo-Fernández, FJ; Calderón Seoane, JE; Torres Morera, LM, 2020) |
| "The rate of pregnant women with an opioid use disorder has risen drastically in the past 20 years, paralleling that in the general population." | 2.66 | Opioid Use and Misuse in Pregnancy. ( Landau, R; Shatil, B, 2020) |
| "When treating pain in the orthopaedic trauma patient opioids have classically represented the mainstay of treatment." | 2.66 | Pain management in the orthopaedic trauma patient: Non-opioid solutions. ( Gessner, DM; Horn, JL; Lowenberg, DW, 2020) |
| " Patients treated with benorylate 4 g reported significantly less pain between 3-6 h after dosage than those treated with placebo." | 2.66 | The efficacy of benorylate in postoperative dental pain. ( Moore, U; Nicholson, E; Rawlins, MD; Seymour, RA; Williams, FM, 1989) |
| "Aceclofenac was administered in single 100 mg doses and paracetamol in single 650 mg doses (both drugs in tablet form) to 60 women aged between 18 and 38 years with post-episiotomal pain." | 2.66 | Evaluation of the analgesic activity and tolerability of aceclofenac in the treatment of post-episiotomy pain. ( Movilia, PG, 1989) |
| "Ibuprofen 400 mg was more effective than acetaminophen 1000 mg for the sum of pain intensity difference, total pain relief, and reduction of pain by more than 50% (P less than ." | 2.66 | Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain. ( Baybutt, RI; Schachtel, BP; Thoden, WR, 1989) |
| "Ibuprofen 400 mg was more effective than acetaminophen 1000 mg for Sum Pain Intensity Difference (SPID), Total Pain Relief (TOTPAR), sum pain half-gone, and overall evaluation (P less than ." | 2.66 | Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study. ( Cohn, P; Cooper, SA; Gelb, S; Goldman, E; Schachtel, BP, 1989) |
| "Flurbiprofen was significantly superior to the acetaminophen codeine combination with respect to the number of hours until remedication." | 2.66 | Evaluation of flurbiprofen, acetaminophen, an acetaminophen-codeine combination, and placebo in postoperative oral surgery pain. ( Beaver, WT; Burchfield, WH; Butterworth, GA; Forbes, JA; Rosenmertz, SK; Selinger, LR; Yorio, CC, 1989) |
| "One hundred sixty-one patients with postoperative pain were treated at a single center in a double-blind, randomized, parallel study designed to compare the efficacy and safety of single oral doses of ketoprofen (50 and 150 mg), an acetaminophen (650 mg) plus codeine (60 mg) combination, and placebo." | 2.66 | Double-blind parallel comparison of ketoprofen (Orudis), acetaminophen plus codeine, and placebo in postoperative pain. ( Baird, WM; Turek, MD, 1988) |
| "With suprofen, there were 8 moderate results and 4 insufficient ones." | 2.66 | Suprofen versus paracetamol after oral surgery. ( Boering, G; Reijntjes, RJ; van Rijn, LJ; Wesseling, H, 1987) |
| "Flupirtine was given as a single dose of 100 mg (one capsule) or as a single day's treatment (100 mg t." | 2.66 | Flupirtine: the first Italian experience. ( Ceccarelli, G; Ciampini, M; Frontespezi, S, 1987) |
| "Flupirtine was given in oral doses of 100 to 300 mg, with a maximum daily dose of 600 mg to patients with pain resulting from episiotomy, surgical or dental procedures." | 2.66 | Clinical experience with flupirtine in the U.S. ( Arndt, WF; McMahon, FG; Montgomery, PA; Newton, JJ; Perhach, JL, 1987) |
| "When acetaminophen was administered before surgery, the onset of peak pain was delayed and patient discomfort was decreased 3, 4, and 5 hours after surgery." | 2.66 | Analgesic regimens for third molar surgery: pharmacologic and behavioral considerations. ( Moore, PA; Seldin, EB; Stevens, CM; Werther, JR, 1986) |
| "Acetaminophen was no better than placebo." | 2.66 | Effect of pretreatment with acetaminophen-propoxyphene for oral surgery pain. ( Desjardins, PJ; Liashek, P; Triplett, RG, 1987) |
| "Acetaminophen, 1000 mg, was statistically superior to 500 mg acetaminophen, demonstrating assay sensitivity." | 2.66 | Ketorolac and acetaminophen for orthopedic postoperative pain. ( Bullingham, RE; Carroll, D; McQuay, HJ; Moore, RA; Poppleton, P; Summerfield, RJ, 1986) |
| " A double-placebo method was used, as dosage regimens for the two treatments were different." | 2.66 | The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery. ( Olstad, OA; Skjelbred, P, 1986) |
| "Nalbuphine was equally effective as pethidine as a postoperative analgesic, but may have been a less effective supplement to anaesthesia in the doses used in this study." | 2.66 | Analgesic and gastrointestinal effects of nalbuphine--a comparison with pethidine. ( Couch, RA; Mark, A; Slattery, PJ, 1986) |
| "Suprofen was better than cosalgesic in the patients' opinion of initial (p = 0." | 2.66 | Suprofen compared to dextropropoxyphene hydrochloride and paracetamol (Cosalgesic) after extraction of wisdom teeth under general anaesthesia. ( Absi, EG; Rosen, M; Webster, JA, 1985) |
| "Ibuprofen, 400 mg, was compared with 300 mg acetaminophen plus 30 mg of codeine and placebo in 120 post-orthopedic surgery patients with moderate to severe pain." | 2.66 | Efficacy and quality of ibuprofen and acetaminophen plus codeine analgesia. ( Heidrich, G; Kaiko, RF; Slavic-Svircev, V, 1985) |
| "Ibuprofen pretreatment resulted in significantly less pain than placebo or acetaminophen pretreatment as the local anesthetic wore off." | 2.65 | Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine. ( Buckingham, B; Campbell, RA; Cooper, SA; Dionne, RA; Hall, DL, 1983) |
| "Acetaminophen was significantly better than aspirin with respect to the maximum difference in the intensity of pain (P less than 0." | 2.65 | A controlled comparative evaluation of acetaminophen and aspirin in the treatment of postoperative pain. ( Frakes, LA; Mehlisch, DR, 1984) |
| " A statiscally significant dose-response relationship was obtained between the supplementary doses of codeine and analgesic efficacy." | 2.65 | Paracetamol plus supplementary doses of codeine. An analgesic study of repeated doses. ( Ahlström, U; Bångens, S; Hellem, S; Johansson, G; Jönsson, E; Nordh, PG; Persson, G; Quiding, H, 1982) |
| " Plasma concentrations of paracetamol were measured and pharmacokinetic variables were determined." | 2.65 | Pharmacokinetics of parenteral paracetamol and its analgesic effects in post-operative dental pain. ( Rawlins, MD; Seymour, RA, 1981) |
| " 5 On the day of operation 18 patients reported adverse effects like nausea, dizziness and drowsiness with paracetamol + codeine, while only 3 patients experienced side effects with paracetamol alone (P less than 0." | 2.65 | Codeine added to paracetamol induced adverse effects but did not increase analgesia. ( Løkken, P; Skjelbred, P, 1982) |
| "Sixty patients suffering moderate postoperative pain after bone surgery were divided randomly into 3 treatment groups on the day following operation." | 2.64 | Effect of paracetamol, mephenoxalone and their combination on pain following bone surgery. ( Eskenazi, J; Livio, JJ; Nikiforidis, T; Schelling, JL, 1976) |
| "Randomized controlled trials evaluating postoperative pain after laparoscopic hysterectomy published between January 1996 and May 2018 were retrieved, according to the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines, from the EMBASE and MEDLINE databases and the Cochrane Register of Controlled Trials." | 2.61 | Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations. ( Bonnet, F; Bonnet, MP; Joshi, GP; Lirk, P; Thiry, J, 2019) |
| "Anxiety reduction may lead to less postoperative pain." | 2.61 | Postoperative Pain Management in Dermatologic Surgery: A Systematic Review. ( Golda, N; Saco, M, 2019) |
| "Acute postoperative pain is of considerable significance, and the late development of neuropathic pain syndrome is also an issue." | 2.58 | Postoperative analgesia after pulmonary resection with a focus on video-assisted thoracoscopic surgery. ( Addesa, S; Baldo, G; Carpanese, V; Lena, E; Lovadina, S; Lucangelo, U; Moro, V; Umari, M, 2018) |
| "Therefore, the optimal postoperative pain management (PPM) applying multimodal analgesia (MA) is one of the most important components of ERAS." | 2.58 | Role of Multimodal Analgesia in the Evolving Enhanced Recovery after Surgery Pathways. ( Benetis, R; Bilskienė, D; Gelman, D; Gelmanas, A; Macas, A; Naudžiūnas, A; Sadauskas, S; Širvinskas, E; Tamošiūnas, R; Urbanaitė, D, 2018) |
| "Acetaminophen does not inhibit this synthesis at the inflammatory site." | 2.55 | Pharmacology of Acetaminophen, Nonsteroidal Antiinflammatory Drugs, and Steroid Medications: Implications for Anesthesia or Unique Associated Risks. ( Candido, KD; Knezevic, NN; Perozo, OJ, 2017) |
| "Severe acute postoperative pain is also strongly associated with persistent pain after cesarean delivery." | 2.55 | Postcesarean delivery analgesia. ( Butwick, AJ; Carvalho, B, 2017) |
| "The primary outcomes were postoperative pain scores and opioid consumption." | 2.55 | Intravenous acetaminophen as an adjunct to multimodal analgesia after total knee and hip arthroplasty: A systematic review and meta-analysis. ( Du, S; Sun, Y; Yang, L, 2017) |
| "Mechanistic approaches and multimodal analgesic techniques have been clearly demonstrated to be the most effective pain management strategy to improve outcomes." | 2.55 | Analgesia in the surgical intensive care unit. ( Brudney, CS; Ehieli, E; Pyati, S; Yalamuri, S, 2017) |
| "Less postoperative pain typically is associated with a minimally invasive hysterectomy compared with a laparotomy approach; however, poor pain control can still be an issue." | 2.55 | Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review. ( As-Sanie, S; Barron, KI; Blanton, E; Lamvu, G; Patanwala, I; Tu, FF; Witzeman, K, 2017) |
| "Optimal postoperative pain control allows for faster recovery, reduced complications, and improved patient satisfaction." | 2.55 | The Role of Multimodal Analgesia in Spine Surgery. ( Kreitz, T; Kurd, MF; Schroeder, G; Vaccaro, AR, 2017) |
| "NSAIDs are safe and effective in the treatment of postoperative pain, and they should be administered to all postoperative surgical patients unless contraindicated." | 2.53 | NSAIDs in the Treatment of Postoperative Pain. ( Bah, M; Gupta, A, 2016) |
| "Morphine was required by only two patients per group (no difference in dosage or frequency)." | 2.52 | Is single incision pediatric endoscopic surgery more painful than standard laparoscopy in children? Personal experience and review of the literature. ( Ade-Ajayi, N; Cancelliere, LA; Desai, AP; Kemal, KI; Patel, S; Zani, A, 2015) |
| "The optimal management of postoperative pain using multimodal analgesia is a key component of Enhanced Recovery After Surgery (ERAS)." | 2.52 | Optimizing pain management to facilitate Enhanced Recovery After Surgery pathways. ( Gan, TJ; Law, LS; Tan, M, 2015) |
| "Acute postoperative pain occurs as a result of tissue damage following surgery." | 2.52 | As required versus fixed schedule analgesic administration for postoperative pain in children. ( Conlon, JA; Hobson, A; Wiffen, PJ, 2015) |
| "Acetaminophen is a commonly used pediatric medication that has recently been approved for intravenous use in the United States." | 2.52 | Intravenous acetaminophen use in pediatrics. ( Shastri, N, 2015) |
| "Gabapentinoid treatment was associated with increased sedation, dizziness and visual disturbances, but the clinical relevance needs clarification." | 2.50 | Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review. ( Dahl, JB; Hamunen, K; Hansen, MS; Kjer, JJ; Kontinen, VK; Mathiesen, O; Nikolajsen, L; Pommergaard, HC; Rosenberg, J; Wetterslev, J, 2014) |
| "Acetaminophen is an old drug that is now available in an intravenous formulation." | 2.50 | OFIRMEV: an old drug becomes new again. ( Nishimoto, RN, 2014) |
| "Acetaminophen (paracetamol) is a familiar agent for treating many types of pain, including postsurgical pain." | 2.48 | Continuous multimechanistic postoperative analgesia: a rationale for transitioning from intravenous acetaminophen and opioids to oral formulations. ( Labhsetwar, SA; Pergolizzi, JV; Raffa, RB; Tallarida, R; Taylor, R, 2012) |
| "Postoperative chronic pain in spine surgery can be caused by damage or instability of spinal column; pressure on nerves or segment of spinal cord; or can be due to long lasting nociception caused by inflammation, infection or tumour." | 2.48 | [Chronic pain following spine surgery]. ( Derbent, A; Uyar, M; Yilmaz, B, 2012) |
| "paracetamol for acute postoperative pain in adults or children." | 2.47 | Single-dose intravenous paracetamol or propacetamol for prevention or treatment of postoperative pain: a systematic review and meta-analysis. ( Cepeda, MS; Farhat, T; Francia, MB; McNicol, ED; Schumann, R; Tzortzopoulou, A, 2011) |
| " formulation of APAP represents a safe and effective first-line analgesic agent for the treatment of acute mild-to-moderate pain in the perioperative setting when oral agents may be impractical or when rapid onset with predictable therapeutic dosing is required." | 2.47 | Perioperative intravenous acetaminophen and NSAIDs. ( Smith, HS, 2011) |
| " Subanaesthetic doses of ketamine have an opioid-sparing effect, but the optimal dosing regimen is uncertain." | 2.47 | [Post-operative pain management in hospitals]. ( Borchgrevink, PC; Fredheim, OM; Kvarstein, G, 2011) |
| "To determine which class of non-opioid analgesics - paracetamol (acetaminophen), NSAIDs or COX-2 inhibitors - is the most effective at reducing morphine consumption and associated adverse effects when used as part of multimodal analgesia following major surgery." | 2.46 | Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review. ( Jenkins, B; Maund, E; McDaid, C; Rice, S; Woolacott, N; Wright, K, 2010) |
| " To formulate regimens properly, it is essential to appreciate basic pharmacological principles and appropriate dosage strategies for each of the available analgesic classes." | 2.46 | Pain management: Part 1: Managing acute and postoperative dental pain. ( Becker, DE, 2010) |
| "Acetaminophen has unique analgesic and antipyretic properties." | 2.46 | Intravenous acetaminophen. ( Jahr, JS; Lee, VK, 2010) |
| "Codeine has opioid-related adverse effects and may not be safe during breastfeeding in the postpartum period for all neonates." | 2.45 | Codeine-acetaminophen versus nonsteroidal anti-inflammatory drugs in the treatment of post-abdominal surgery pain: a systematic review of randomized trials. ( Koren, G; Landsmeer, ML; Nauta, M, 2009) |
| "The prevalences of complex regional pain syndrome, phantom limb pain, chronic donor-site pain, and persistent pain following total joint arthroplasty are alarmingly high." | 2.44 | Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques. ( Buvanendran, A; Reuben, SS, 2007) |
| "A population pharmacokinetic analysis of paracetamol time-concentration profiles (846 observations) from 144 children [postconception age (PCA) 27 weeks-14 years] was undertaken using nonlinear mixed effects models (NONMEM)." | 2.43 | Pediatric intravenous paracetamol (propacetamol) pharmacokinetics: a population analysis. ( Allegaert, K; Anderson, BJ; Autret-Leca, E; Boccard, E; Pons, G, 2005) |
| "Acetaminophen was less effective for pain relief after orthopaedic procedures than after dental procedures." | 2.43 | Predicting postoperative analgesia outcomes: NNT league tables or procedure-specific evidence? ( Bonnet, F; Gray, A; Kehlet, H; Rawal, N, 2005) |
| "To assess analgesic drugs in the treatment of postoperative pain after traumatic and orthopaedic surgery (TOS)." | 2.43 | Analgesics for pain after traumatic or orthopaedic surgery: what is the evidence--a systematic review. ( Aguilera, C; Laporte, JR; Montané, E; Vallano, A; Vidal, X, 2006) |
| " However, if paracetamol is dosed according to traditional recommendations (about 20 mg/kg body weight) frequently a sufficient analgetic effect cannot be achieved immediately after painful interventions." | 2.41 | [Paracetamol in childhood. Current state of knowledge and indications for a rational approach to postoperative analgesia]. ( Brambrink, AM; Mantzke, US, 2002) |
| "Treatment of postoperative pain is imperative for inpatients, but is even more important for patients who are treated on an outpatient basis." | 2.41 | Treatment of postoperative pain after ophthalmic surgery. ( Coppens, M; Mortier, E; Versichelen, L, 2002) |
| "The standard pillar of postoperative treatment of severe pain is the use of opioids." | 2.41 | Non-opioid postoperative analgesia. ( Dahl, V; Raeder, JC, 2000) |
| " The result was supported a rational dose-response relationship for different doses of paracetamol and codeine in 17 additional trials with 1,195 patients." | 2.41 | Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg. ( Gavaghan, D; McQuay, HJ; Moore, RA; Smith, LA, 2001) |
| " The dosage of paracetamol must take into account the pharmacokinetic properties of the drug in children." | 2.41 | Nonsteroidal anti-inflammatory drugs and paracetamol in children. ( Camu, F; Van de Velde, A; Vanlersberghe, C, 2001) |
| "A high standard of acute postoperative pain control is achievable, using a comprehensive multimodal approach, resulting in improved patient outcomes." | 2.41 | Acute postoperative pain management: a review. ( Reid, RI, 2001) |
| "This could be shown for dental but not postsurgical pain, because more patients were available for the former." | 2.41 | Combination analgesic efficacy: individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain. ( Edwards, JE; McQuay, HJ; Moore, RA, 2002) |
| "Quantitative reviews of postoperative pain management have demonstrated that the number of patients needed to treat for one patient to achieve at least 50% pain relief (NNT) is 2." | 2.41 | Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review. ( Hyllested, M; Jones, S; Kehlet, H; Pedersen, JL, 2002) |
| " One study of single-dose administration of rectal paracetamol 40-60 mg kg(-1) and three studies of repeat dosing with 14-20 mg kg(-1) showed significant analgesic efficacy, while studies of a single dose of 10-20 mg kg(-1) were negative." | 2.41 | Rectal and parenteral paracetamol, and paracetamol in combination with NSAIDs, for postoperative analgesia. ( Dahl, JB; Møiniche, S; Rømsing, J, 2002) |
| " Tramadol showed a dose-response for analgesia in both postsurgical and dental pain patients." | 2.40 | Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics. ( McQuay, JH; Moore, AR, 1997) |
| "2231 patients with postsurgical pain, arthritis, and musculoskeletal pain reported in 26 randomised controlled trials." | 2.40 | Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol. ( Li Wan Po, A; Zhang, WY, 1997) |
| " Dose-response relationships show that higher doses of ibuprofen may be particularly effective." | 2.40 | Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. ( McQuay, HJ; Moore, RA, 1998) |
| "Tramadol hydrochloride is a novel, centrally acting analgesic with two complementary mechanisms of action: opioid and aminergic." | 2.40 | Pain management in dental practice: tramadol vs. codeine combinations. ( Moore, PA, 1999) |
| "The objective of this study was to quantify the analgesic efficacy of paracetamol and its combination with codeine or caffeine through a systematic overview and meta-analysis of relevant randomized controlled trials (RCTs)." | 2.39 | Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain--a meta-analysis. ( Li Wan Po, A; Zhang, WY, 1996) |
| "Pain is the most common symptom of acute pancreatitis (AP), and opioids have been utilized as the cornerstone of treatment." | 1.91 | Analgesic Patterns and Opioid Administration in Children Hospitalized With Acute Pancreatitis. ( Abu-El-Haija, M; Gorbounova, I; Palermo, TM; Tham, SW, 2023) |
| "Acute pain is a common symptom in children of all ages, and is associated with a variety of conditions." | 1.91 | Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT). ( Chiarugi, A; Cortis, E; D'Avino, A; Lanari, M; Marchisio, PG; Parri, N; Silvagni, D; Staiano, A; Vezzoli, C; Zampogna, S, 2023) |
| "Acetaminophen was administered as an additional antalgic drug on demand up to 3 g per day." | 1.91 | Multimodal evaluation of locoregional anaesthesia efficacy on postoperative pain after robotic pulmonary lobectomy for NSCLC: a pilot study. ( Alessandrini, G; Ambrogi, V; Coccia, C; Facciolo, F; Forcella, D; Gallina, FT; Melis, E; Papale, M; Pierconti, F; Sardellitti, F; Tajè, R, 2023) |
| " Plasma samples were collected, concentrations of drug and metabolites determined via liquid chromatography-mass spectrometry, and pharmacokinetic analyses were performed." | 1.91 | Pharmacokinetics and effects of codeine in combination with acetaminophen on thermal nociception in horses. ( Kanarr, K; Kass, PH; Knych, HK; McKemie, DS; Tueshaus, T, 2023) |
| "Postoperative pain is commonly severe for 1-2 weeks, but parental analgesia concerns lead to poor analgesia prescription compliance and under administration." | 1.91 | A service evaluation of the impact of parental information provision on analgesia administration at home posttonsillectomy. ( Bew, S; Bliss, A; Gupta, E; Nicholls, A, 2023) |
| "Postoperative pain was assessed using a numeric rating scale (NRS) with scores ranging from 0 to 10." | 1.91 | Efficacy and safety of patient-controlled thoracic epidural analgesia alone versus patient-controlled intravenous analgesia with acetaminophen after laparoscopic distal gastrectomy for gastric cancer: a propensity score-matched analysis. ( Ebara, G; Fujihata, S; Fujita, S; Lee, S; Matsui, K; Miyawaki, Y; Nishibeppu, K; Oya, S; Sakuramoto, S; Sato, H; Sugita, H; Yamashita, K, 2023) |
| "The choice of IV or other analgesics in treating hip fractures affects analgesic usage, side effects, medical costs, and patient outcomes." | 1.91 | Outcomes of hip fracture treatment with intravenous morphine and with other analgesics: postoperative analgesic medical expense, severity of pain and hospitalisation-a retrospective study. ( Nimkingratana, P; Phinyo, P; Srichan, R; Tanasombatkul, K, 2023) |
| "Propacetamol is a prodrug form of paracetamol (APAP) licensed for human use as a pain reliever in postoperative care." | 1.72 | Propacetamol in dogs: First description of its pharmacokinetics after intravenous and oral administration. ( Gajda, A; Gbylik-Sikorska, M; Giorgi, M; Kim, TW; Lisowski, A; Pietruk, K; Poapolathep, A; Sartini, I; Łebkowska-Wieruszewska, B, 2022) |
| "Parameters related to postoperative pain control were compared between patients who underwent robotic transabdominal lateral adrenalectomy with (after December 2018) or without laparoscopic TAP block (control group) (before December 2018) by one surgeon." | 1.72 | The efficacy of laparoscopic transversus abdominis plane block on reducing postoperative narcotic usage in patients undergoing minimally invasive adrenalectomy. ( Avci, SN; Berber, E; Erten, O; Isiktas, G, 2022) |
| "· ERAS protocols improve postoperative pain control and lower postoperative opioid use." | 1.72 | Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management. ( Berghella, V; Cao, CD; Dayaratna, S; Felder, L; Konys, C; Mercier, R; Weerasooriya, N, 2022) |
| "Acetaminophen was mixed with all 18 solutions and was examined at time 0, 15, 30, and 60 min." | 1.72 | Compatibility of intravenous acetaminophen with morphine, fentanyl and ketamine in acute pediatric pain setting. ( Chan, MTV; Cheaib, A; O'Loughlin, E; Peng, YG; Williams, R, 2022) |
| "Acetaminophen is a popular, universally used, over-the-counter pain medication contained in more than 600 different products and available in a plethora of dosage forms." | 1.72 | Acetaminophen: Is Too Much of a Good Thing Too Much? ( Donaldson, M; Goodchild, JH, 2022) |
| "Managing acute postoperative pain without opioids is of the utmost importance for the Veteran patient population." | 1.72 | Evaluation of a Novel Multimodal Opioid-Free Postoperative Pain Management Pathway Following Robotic-Assisted Radical Prostatectomy: A Pilot Series in the Veteran Population. ( Badlani, G; Bercu, C; Dutta, R; Hemal, A; Pathak, R, 2022) |
| " An electronic order set provided weight-based dosing and defaulted to non-opioid prescriptions (acetaminophen and ibuprofen)." | 1.72 | Sustaining standardized opioid prescribing practices after pediatric tonsillectomy. ( Alfonso, K; Brown, C; Cordray, H; Evans, S; Goudy, S; Govil, N; Landry, AM; Prickett, KK; Raol, N; Smith, K, 2022) |
| "Complex and invasive postoperative pain regimens for microtia reconstruction with costal cartilage are often utilized." | 1.72 | Pain management after microtia repair with costal cartilage: De-escalation and opioid use reduction. ( Epperson, MV; Kim, HM; Kim, JC; VanHorn, A; Zopf, D, 2022) |
| "Once a baseline incidence is known, predictors for serious ORADEs in surgical inpatients are useful in guiding medical-surgical nurses' opioid safety practices, with more frequent focused respiratory assessments before opioid dosing and closer monitoring when opioids are prescribed postoperatively, especially in higher-risk surgical inpatients." | 1.72 | Incidence of and predictors for serious opioid-related adverse drug events. ( Atem, FD; Denke, L; Khazzam, M, 2022) |
| "Gabapentin has not been shown to improve patient outcomes; however, pregabalin may decrease pain and opioid use after total joint arthroplasty." | 1.72 | A Case Illustrating the Practical Application of the AAOS Clinical Practice Guideline: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery. ( Patzkowski, JC; Patzkowski, MS, 2022) |
| "Standardization of postoperative pain medication doses may also reduce postoperative ED presentations." | 1.72 | Opioid and non-opioid analgesic prescribing practices for pediatric adenotonsillectomy in a tertiary care center. ( Commesso, EA; Eapen, RJ; Einhorn, L; Frank-Ito, DO; Greene, NH; Ji, KSY; Osazuwa-Peters, N; Raynor, EM, 2022) |
| "Acetaminophen first was associated with reduced opioid use on the day prior to and on the day of discharge (3." | 1.72 | Underutilization of Acetaminophen in Older Adult Trauma Patients. ( Agarwal, S; Antonescu, I; Bartz, RR; Cox, CE; Fuller, M; Haines, KL; Krishnamoorthy, V; Ohnuma, T; Raghunathan, K; Vaughan, JG, 2022) |
| "Women with opioid use disorder or postoperative intubation were excluded." | 1.72 | A standardized post-cesarean analgesia regimen reduces postpartum opioid use. ( Antony, KM; Broman, AT; Gnadt, SE; Meyer, MF; Sharma, S, 2022) |
| "Ibuprofen appears to be a safe option for fracture-related pain." | 1.62 | An observational cohort study comparing ibuprofen and oxycodone in children with fractures. ( Ali, S; Carleton, B; Drendel, AL; Johnson, DW; LeMay, S; Manaloor, R; McGrath, PJ; Rosychuk, RJ, 2021) |
| "We analyzed postoperative pain intensity, the incidence rate of acute kidney injury, drug-induced liver injury, and rate of elevation in serum creatinine after open radical prostatectomy." | 1.62 | Comparison between the Effects of Loxoprofen and Acetaminophen on Postoperative Pain Following Radical Prostatectomy: A Propensity Score Matching Analysis. ( Hamada, S; Hamada, Y; Hara, K; Kadowaki, D; Miyamura, S; Nishimura, F; Nojima, M; Oniki, K; Saruwatari, J; Ushijima, T, 2021) |
| "Postoperative pain was measured using a numeric rating scale (NRS) three times per day until discharge." | 1.62 | Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery. ( Kurosaki, T; Morimatsu, H; Ohtani, S; Okazaki, M; Oto, T; Shien, K; Shikatani, Y; Soh, J; Sugimoto, S; Taniguchi, A; Toyooka, S; Yamamoto, H; Yamane, M, 2021) |
| " Opioid outcomes calculated in morphine milligram equivalents per kilogram (MME/kg) per dosage and total prescribed." | 1.62 | Pediatric Post-Tonsillectomy Opioid Prescribing Practices. ( Agamawi, YM; Brinkmeier, JV; Cass, LM; Mouzourakis, M; Pannu, JS, 2021) |
| " The accumulated dosage of acetaminophen given by postoperative day 2 was significantly higher in the Single group versus the Continuous group (55." | 1.62 | The Effect of Continuous Field Block through Intercostal Muscles after Atrial Septal Defect Closure via a Mini-Right Thoracotomy in Pediatric Patients. ( Ishii, Y; Kishikawa, H; Miyagi, Y; Mori, K; Nitta, T; Sakamoto, A; Sasaki, T; Suzuki, K, 2021) |
| "Acetaminophen has been widely used as an analgesic agent after various types of surgery." | 1.62 | The feasibility and safety in using acetaminophen with fentanyl for pain control after liver resection with regards to liver function: A prospective single-center pilot study in Japan. ( Adachi, T; Eguchi, S; Hara, T; Hidaka, M; Ichinomiya, T; Kamada, N; Nakashima, M; Ohyama, K; Soyama, A, 2021) |
| "We investigated postoperative pain intensity and additional analgesic consumption on postoperative day 0, 1, 2, 3, and 5 between the two groups." | 1.62 | Postoperative around-the-clock administration of intravenous acetaminophen for pain control following robot-assisted radical prostatectomy. ( Hayashi, T; Hieda, K; Inoue, S; Miyoshi, H; Teishima, J; Tsutsumi, YM, 2021) |
| "The optimal dosing of post-operative total knee arthroplasty (TKA) narcotics is unclear." | 1.62 | Average narcotic usage in a group of TKA patients following a modern TKA protocol. ( Chapman, DM; Costales, TG; Dalury, DF; Greenwell, PH; Volkmann, MC, 2021) |
| "Acetaminophen was found to increase the AUB with an estimated median difference of 15 (95% CI, 5-25) mm Hg × minutes (P = ." | 1.62 | Effect of Intravenous Acetaminophen on Mean Arterial Blood Pressure: A Post Hoc Analysis of the EFfect of Intravenous ACetaminophen on PosToperative HypOxemia After Abdominal SurgeRy Trial. ( AlGharrash, A; Bakal, O; Bravo, M; Essber, H; Mascha, EJ; Mosteller, L; Pu, X; Rivas, E; Rodriguez-Patarroyo, F; Turan, A, 2021) |
| "Parents completed the Parents' Postoperative Pain Measure (PPPM-D) in addition." | 1.62 | Pain in children undergoing tonsillotomy with alternating ibuprofen and paracetamol - a prospective observational study. ( Dazert, S; Geldermann, N; Georgevici, AI; Gude, P; Herzog-Niescery, J; van Ackeren, K; Vogelsang, H; Volkenstein, S; Weber, TP, 2021) |
| "IV acetaminophen is an integral and effective part of our opioid-sparing multimodal pain regimen in TKA." | 1.56 | Evolution of an Opioid Sparse Pain Management Program for Total Knee Arthroplasty With the Addition of Intravenous Acetaminophen. ( Bosco, JA; Eftekhary, N; Iorio, R; Long, WJ; Schwarzkopf, R; Wiznia, D; Yu, S, 2020) |
| "Remifentanil is an ultrashort-acting opioid that provides quick and efficient analgesia but is associated with the induction of opioid-induced hyperalgesia." | 1.56 | Remifentanil for abdominal surgery is associated with unexpectedly unfavorable outcomes. ( Guenther, F; Heyn, J; Küchenhoff, H; Luchting, B; Niedermayer, S, 2020) |
| "Postoperative pain is a significant cause of morbidity in pediatric anesthesia, which can result in delayed discharge and unplanned hospital admission." | 1.56 | Reducing postoperative pain in children undergoing strabismus surgery: From bundle implementation to clinical decision support tools. ( Ali, U; Balakrishnan, S; Campbell, F; Igbeyi, B; Kotzer, G; Matava, C; Mc Donnell, C; Shackell, K; Tsang, M, 2020) |
| " Results The scheduled dosing group was found to have a statistically significant decrease in pain scores at all time intervals." | 1.56 | The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery. ( Chappelle, J; Poljak, D, 2020) |
| " We sought to evaluate the effectiveness and safety of over the counter dosing of ibuprofen on pain and bleeding rates following ESS." | 1.56 | Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study. ( Davis, GE; Humphreys, IM; Miller, C, 2020) |
| "Fentanyl consumption was significantly higher in group C compared to the other groups at all time intervals (p < 0." | 1.56 | Comparison of types 2 and 3 quadratus lumborum muscle blocks : Open inguinal hernia surgery in patients with spinal anesthesia. ( Ahiskalioglu, A; Ahiskalioglu, EO; Aydin, ME; Bagbanci, O; Karadeniz, E; Kursad, H; Yayik, AM, 2020) |
| "In this Quality Improvement (QI project) it was hypothesized that an increase in dosing intervals for postoperative analgesia when alternating Ibuprofen and Acetaminophen would reduce post-tonsillectomy hemorrhage (PTH) rates for those undergoing tonsillectomies with or without adenoidectomy, while maintaining the standard of postoperative analgesia and reducing visits to the Emergency Room (ER) for reasons other than PTH." | 1.56 | The Effect of Ibuprofen Dosing Interval on Post-Tonsillectomy Outcomes in Children: A Quality Improvement Study. ( Carr, MM; Henderson, K; Mast, G, 2020) |
| "2." | 1.51 | Contemporary Approaches to Postoperative Pain Management. ( Haykal, S; Lalonde, DH; Murphy, AM; Zhong, T, 2019) |
| "In 2014, we started to treat pilonidal sinus disease in our institution with sinus laser-assisted closure (SiLaC) procedure." | 1.51 | The SiLaC procedure for pilonidal sinus disease: long-term outcomes of a single institution prospective study. ( Chahidi, E; Dessily, M; Dziubeck, M; Simonelli, V, 2019) |
| "Managing postoperative pain is important for patients and surgeons." | 1.51 | Prospective Evaluation of Opioid Consumption Following Cubital Tunnel Decompression Surgery. ( Abboudi, J; Foltz, C; Gallant, G; Hozack, BA; Ilyas, AM; Jones, CM; Kirkpatrick, W; Liss, FE; Rivlin, M; Silverman, M; Takei, TR; Wang, ML, 2019) |
| "Oral morphine was prescribed in 59/199 (30% [23; 37]) centres, for home treatment in 25/59 (42% [30; 56]) centres." | 1.51 | Perioperative pain and post-operative nausea and vomiting (PONV) management after day-case surgery: The SFAR-OPERA national study. ( Albaladejo, P; Aubrun, F; Benhamou, D; Bosson, JL; Diemunsch, P; Ecoffey, C; Jouffroy, L; Skaare, K, 2019) |
| "The control of postoperative pain (POP) is a key component of perioperative care." | 1.51 | Postoperative pain after vitreo-retinal surgery is influenced by surgery duration and anesthesia conduction. ( Adembri, C; Barca, F; Caporossi, T; De Gaudio, AR; Di Filippo, A; Loriga, B; Rizzo, S; Signorini, P; Tofani, L, 2019) |
| "Midazolam was used in 95 patients (56%), with an average dose of 35 (±14) μg/kg/h." | 1.51 | Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study. ( Benahmed-Canat, A; Canat, G; Claris, O; Kassai, B; Nguyen, KA; Paret, N; Plaisant, F; Rabilloud, M; Riche, B, 2019) |
| "The purpose of this study is to compare postoperative pain scores between children undergoing tonsillectomy and adenoidectomy (T&A) surgery and their parents, identify potential predictors for this disagreement, and determine possible impact on analgesic administration." | 1.51 | Children and their parents' assessment of postoperative surgical pain: Agree or disagree? ( Fortier, MA; Gold, JI; Golianu, B; Jenkins, BN; Kain, ZN; Kaminsky, O; Kaplan, SH; Stevenson, RS; Zuk, J, 2019) |
| "We could not show that perioperative ivAPAP reduces inpatient opioid prescription with subsequent reduced odds for adverse outcomes." | 1.48 | Intravenous Acetaminophen Does Not Reduce Inpatient Opioid Prescription or Opioid-Related Adverse Events Among Patients Undergoing Spine Surgery. ( Cozowicz, C; Mazumdar, M; Memtsoudis, SG; Mörwald, EE; Poeran, J; Zubizarreta, N, 2018) |
| "To determine efficacy of postoperative pain control using nonopioid pain regimen vs traditional opioids for all aesthetic plastic surgery procedures." | 1.48 | Transition to Nonopioid Analgesia Does Not Impair Pain Control After Major Aesthetic Plastic Surgery. ( Lombana, NF; Moliver, CL; Nguyen, TC; Zavlin, D, 2018) |
| "Management of postoperative pain is one of the most important components in postoperative care, because most patients have pain after dental surgery." | 1.48 | Effective Postoperative Analgesia Using Intravenous Flurbiprofen and Acetaminophen. ( Doi, M; Irifune, M; Mukai, A; Shimizu, Y; Yoshida, K; Yoshida, M, 2018) |
| "Secondary outcome variables were postoperative pain intensity measured using the numeric rating scale (0 to 10) and length of hospital stay." | 1.48 | Postoperative Pain and Opioid Analgesic Requirements After Orthognathic Surgery. ( Chigurupati, R; Mehra, P; Mobini, A, 2018) |
| "Time to flatus was decreased by 1." | 1.48 | Liposomal bupivacaine reduces narcotic use and time to flatus in a retrospective cohort of patients who underwent laparotomy. ( Bamboat, ZM; Burnett, A; Faley, B; Nyirenda, T, 2018) |
| "Acute pain was associated with a variety of surgical procedures and patients were examined before and after surgical procedures." | 1.48 | The glycation products before and after therapy for acute and chronic pain. ( Fricová, J; Holeček, V; Houdek, K; Lejčko, J; Nedvídek, J; Rokyta, R; Trefil, L, 2018) |
| "Patients with gastric cancer who underwent surgery in our hospital from October 2016 to December 2016 were enrolled in this prospective study." | 1.46 | [Application of multimodal analgesia in radical gastrectomy for gastric cancer patients: a prospective nonrandomized controlled study]. ( Chen, X; Hu, J; Li, K; Liu, F; Liu, K; Song, X; Yang, K; Zhang, W, 2017) |
| "This study was aimed to evaluate the efficacy of preemptive analgesia (PA) by using celecoxib combined with low-dose tramadol/acetaminophen (tramadol/APAP) in treating post-operative pain of patients undergoing unilateral total knee arthroplasty (TKA)." | 1.46 | Preemptive analgesia by using celecoxib combined with tramadol/APAP alleviates post-operative pain of patients undergoing total knee arthroplasty. ( Luo, J; Xu, Z; Zhang, H; Zhang, J; Zhou, A, 2017) |
| " Suggested dosing regimens are proposed." | 1.46 | Oral Multimodal Analgesia for Total Joint Arthroplasty. ( Balch, KR; Dalury, DF; Golladay, GJ; Jiranek, WA; Satpathy, J, 2017) |
| "Postoperative pain is well known and usually disturbing complication of surgery." | 1.46 | Neutrophil lymphocyte ratio predicts postoperative pain after orthognathic surgery. ( Alkan, M; Altundağ, SK; Arslan, M; Ataç, MS; Bozkaya, S; Işik, B; Şimşek, B; Turgut, HC, 2017) |
| "Outcome measures were postsurgical pain at rest and during walking, consumption of opioids for pain rescue, knee swelling and knee range of motion, and complications." | 1.46 | Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty. ( Hansen, TB; Munk, S; Rytter, S; Stilling, M, 2017) |
| "Postoperative pain is a common complication of laparoscopic living-donor nephrectomies (LLDNs)." | 1.46 | Intravenous Acetaminophen for Postoperative Pain Management in Patients Undergoing Living Laparoscopic Living-Donor Nephrectomy. ( Baker, WL; Martin, ST; Rochon, C; Sheiner, PA; Tencza, EM; Vu, V, 2017) |
| " There is limited literature on the chronic use of opioids pre-TKA and post-TKA." | 1.46 | Chronic Use of Opioids Before and After Total Knee Arthroplasty: A Retrospective Cohort Study. ( Graves, SE; Hansen, CA; Inacio, MCS; Pratt, NL; Roughead, EE, 2017) |
| " Dosing could not be determined, so it was not possible to quantify utilization of IV-APAP or ascertain differences in opioid consumption between the 2 groups." | 1.46 | Hospitalization Costs for Patients Undergoing Orthopedic Surgery Treated With Intravenous Acetaminophen (IV-APAP) Plus Other IV Analgesics or IV Opioid Monotherapy for Postoperative Pain. ( Eaddy, MT; Lunacsek, OE; Maiese, BA; Pham, AT; Shah, MV; Wan, GJ, 2017) |
| "A reliable mechanical hyperalgesia was observed at 2 h post-surgery and lasted for 4 days." | 1.43 | Antinociceptive effects of vitexin in a mouse model of postoperative pain. ( Jiang, B; Li, JX; Liu, CP; Mao, LN; Sun, YH; Zhang, W; Zhu, Q, 2016) |
| "Pretreatment with sinomenine did not alter the mechanical hypersensitivity post-surgery." | 1.43 | Antinociceptive effects of sinomenine in a rat model of postoperative pain. ( Jiang, B; Li, JX; Liu, C; Mao, L; Sun, Y; Zhang, W; Zhu, Q, 2016) |
| "Study selectionAll Cochrane reviews of RCTs between 1999 to 2015, conducted in adults examining the adverse events associated with single dose oral analgesics used for acute post-operative pain were considered." | 1.43 | Single dose oral analgesics for postoperative pain have few adverse events. ( Wong, YJ, 2016) |
| "Acute pain following inguinal hernia repair can be difficult to treat." | 1.42 | Development and characterization of a novel, anatomically relevant rat model of acute postoperative pain. ( Bannerton, K; Bree, D; Broom, DC; Finn, DP; Kelly, JP; Moriarty, O; Morris, B; O'Mahony, CM; Roche, M, 2015) |
| "Registered nurses (RNs) play a pivotal role in treating pain and preventing and recognizing the adverse effects (AEs) of analgesics in patients with dementia." | 1.42 | Registered Nurses' Knowledge about Adverse Effects of Analgesics when Treating Postoperative Pain in Patients with Dementia. ( Hartikainen, S; Kankkunen, P; Kvist, T; Rantala, M, 2015) |
| "We investigate 24 children, undergoing umbilical hernia repair; mean age of 3 years (age range: 20-65 months)." | 1.42 | [Effectiveness of Sacral Intervertebral Epidural Block for Umbilical Hernia Repair in Children]. ( Furuya, A; Kiuchi, R; Kondo, S; Nagamine, N; Nonaka, A; Suzuki, S, 2015) |
| "Morphine requirements were markedly less for CLAWI." | 1.42 | Local anesthetic wound infusion versus standard analgesia in paediatric post-operative pain control. ( Albetyn, H; Cox, SG; Machoki, MS; Millar, AJ; Numanoglu, A; Thomas, J, 2015) |
| "I." | 1.42 | Effect of i.v. acetaminophen on total hip or knee replacement surgery: a case-matched evaluation of a national patient database. ( Ang, RY; Apfel, C; Jahr, JR; Kelly, CL; Oderda, GM, 2015) |
| "Abdominal pain was generally moderate for most patients and decreased significantly after about 4 days." | 1.40 | Pain and analgesic use after robot-assisted radical prostatectomy. ( Badani, KK; Bergman, A; Korets, R; Motamedinia, P; Shapiro, EY; Weinberg, AC; Woldu, SL, 2014) |
| "Tapentadol is a new partial µ-receptor opioid agonist with a combined action on norepinephrine-induced analgesia, representing a promising drug in terms of less side effects at equianalgesic doses compared with pure agonists." | 1.40 | Opioids in the treatment of postoperative pain: old drugs with new options? ( Raeder, J, 2014) |
| "Nurses play a pivotal role in treating postoperative pain in patients with dementia and monitoring the effects of administered analgesics." | 1.40 | Analgesics in postoperative care in hip fracture patients with dementia - reported by nurses. ( Hartikainen, S; Kankkunen, P; Kvist, T; Rantala, M, 2014) |
| "Codeine is a mild opioid widely used as an analgesic in various age groups, including various pediatric settings." | 1.40 | Doing without codeine: why and what are the alternatives? ( Barbi, E; Benini, F, 2014) |
| " Overall adverse events in the 2 treatment groups were also compared." | 1.40 | Efficacy and safety of transdermal fentanyl in the control of postoperative pain after photorefractive keratectomy. ( Bae, JH; Choi, CY; Kim, JM; Kim, YJ; Lee, YW, 2014) |
| " In order to assess covariate effects of intravenous paracetamol disposition in adults, pharmacokinetic data on discrete studies were pooled." | 1.40 | Covariates of intravenous paracetamol pharmacokinetics in adults. ( Allegaert, K; Anderson, BJ; de Maat, MM; Olkkola, KT; Owens, KH; Van de Velde, M, 2014) |
| "Expectation of postsurgical pain is part of this construct and should be considered preoperatively." | 1.40 | Less is more: limiting narcotic prescription quantities for common orthopedic procedures. ( O'Neill, DF; Webb Thomas, C, 2014) |
| "We enrolled endometrial cancer patients undergoing open abdominal hysterectomy with lymphadenectomy by the same surgeon." | 1.40 | Multimodal pain control is associated with reduced hospital stay following open abdominal hysterectomy. ( Jennings, PW; Santoso, JT; Ulm, MA; Wan, JY, 2014) |
| " Two hundred forty-one patients (80%) were appropriately dosed, whereas 59 (20%) patients were not appropriately dosed based on the FDA-approved dosing." | 1.40 | Postmarketing review of intravenous acetaminophen dosing based on Food and Drug Administration prescribing guidelines. ( dela Cruz Ubaldo, C; Hall, NS; Le, B, 2014) |
| "Ibuprofen was found to be a superior analgesic to paracetamol at several doses, with high quality evidence suggesting that ibuprofen 400 mg is superior to 1000 mg paracetamol based on pain relief (estimated from TOTPAR data) and the use of rescue medication meta-analyses." | 1.40 | Ibuprofen is superior to paracetamol for pain relief following third molar removal. ( Ferraiolo, DM; Veitz-Keenan, A, 2014) |
| "The incidence of severe postoperative pain is not significantly related to CK level." | 1.40 | Validity of creatine kinase as an indicator of muscle injury in spine surgery and its relation with postoperative pain. ( Bagó Granell, J; Lombao Iglesias, D; Vilor Rivero, T, 2014) |
| " Postoperatively, all patients were prescribed paracetamol (acetaminophen) on the basis of their weight; the standard pediatric dosage of this agent at the time of our study was 60 mg/kg/day." | 1.39 | A prospective study of parents' compliance with their child's prescribed analgesia following tonsillectomy. ( Amin, M; Colreavy, MP; Lennon, P, 2013) |
| "We compared an approach using scheduled analgesic dosing with as-needed analgesic dosing in patients after hip fracture surgery, to compare these approaches in terms of (1) resting and dynamic pain intensity, (2) postoperative patient mobility, and (3) functional end points." | 1.39 | Scheduled analgesic regimen improves rehabilitation after hip fracture surgery. ( Cheung, LP; Chin, RP; Ho, CH, 2013) |
| " Following implant surgery, postoperative pain was rated moderate or severe in 25/28 patients (89 percent), requiring prn analgesic dosing for up to 3 days in 14/25 individuals (56 percent)." | 1.39 | Characterization and treatment of postsurgical dental implant pain employing intranasal ketorolac. ( Bockow, R; Bodner, L; Hersh, EV; Hutcheson, M; Korostoff, J; Pinto, A; Secreto, SA, 2013) |
| "Implementing an algorithm for postoperative pain management resulted in a clinically relevant reduction of postoperative pain." | 1.39 | [An algorithm for postoperative pain management in visceral and thoracic surgery: an observational study]. ( Fass, J; Gehling, M; Klammer, A; Klammer, F; Tryba, M, 2013) |
| " We conclude that repeated dosing through transversus abdominis plane catheters may be offered to women as an alternative or adjuvant to intrathecal morphine." | 1.38 | Transversus abdominis plane catheters for post-cesarean delivery analgesia: a series of five cases. ( Bollag, L; Landau, R; Ortner, C; Richebe, P, 2012) |
| " In addition, we compiled dose-response data for 4 commonly used analgesics: buprenorphine, carprofen, ketoprofen, and acetaminophen." | 1.38 | Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice. ( King, OD; Matsumiya, LC; Mogil, JS; Sorge, RE; Sotocinal, SG; Tabaka, JM; Wieskopf, JS; Zaloum, A, 2012) |
| "Lymphangioma is a congenital malformation of the lymphatic system, often involving areas of the head and neck." | 1.38 | Anaesthetic management of a child posted for excision of lymphangioma of the tongue. ( Bhalla, AP; Garg, R; Mehta, S, 2012) |
| "To determine the risk of postoperative hemorrhage associated with the use of analgesic drugs including paracetamol, metamizole sodium and ibuprofen after pediatric tonsillectomy." | 1.38 | The effect of paracetamol, metamizole sodium and ibuprofen on postoperative hemorrhage following pediatric tonsillectomy. ( Kapusuz, Z; Özkiriş, M; Saydam, L; Yildirim, YS, 2012) |
| " Individual pharmacokinetic profiles were calculated assuming a linear one-compartment model with instantaneous input, first-order output." | 1.38 | The pharmacokinetics of a high intravenous dose of paracetamol after caesarean delivery: the effect of gestational age. ( Allegaert, K; de Hoon, J; Deprest, J; Devlieger, R; Hopchet, L; Kulo, A; van de Velde, M; Verbesselt, R, 2012) |
| "Untreated postoperative pain is an important ethical and financial issue that can lead to unnecessary suffering and prolonged stays in hospital." | 1.37 | Reducing postoperative pain by changing the process. ( Armstrong, D; Boardman, C; Coulthard, P; Crawford, FI, 2011) |
| "Data on practice and quality of postoperative pain treatment by anaesthesiologists after ambulatory surgery are sparse." | 1.37 | [Postoperative pain management after ambulatory surgery. A survey of anaesthesiologists]. ( Lux, EA; Meissner, W; Stamer, U; Wiebalck, A, 2011) |
| "Bupivacaine was injected intraoperatively in all UMBP and 89% of LAP infants." | 1.37 | Open transumbilical pyloromyotomy: is it more painful than the laparoscopic approach? ( Aspirot, A; Beaunoyer, M; Lemoine, C; Morris, M; Paris, C; Vali, K, 2011) |
| "Delirium is a side effect associated with narcotic analgesics, with a higher incidence in the elderly." | 1.37 | Oxycodone induced delirium and agitation in an elderly patient following total right knee arthroplasty. ( Crane, JH; Suda, KJ, 2011) |
| "Gastrectomy leads to pathophysiological changes within the alimentary tract, which may affect drug absorption and pharmacokinetic parameters (PK)." | 1.37 | Comparison of the pharmacokinetics of paracetamol from two generic products in patients after total gastric resection. ( Grabowski, T; Grześkowiak, E; Kamińska, A; Kokot, ZJ; Murawa, D; Murawa, P; Połom, K; Sobiech, M; Szałek, E; Urbaniak, B; Wolc, A, 2011) |
| " Differences between the protocols were frequency of pain measurement, more frequent use of local anesthesia and higher dosage of Acetaminophen." | 1.36 | Perioperative analgesia strategies in fast-track pediatric surgery of the kidney and renal pelvis: lessons learned. ( Dingemann, J; Kuebler, JF; Osthaus, WA; Reismann, M; Ure, BM; von Kampen, M; Wolters, M, 2010) |
| "Objectives:Despite efforts to improve acute postoperative pain management, a substantial number of patients still experience moderate to severe pain during the immediate postoperative days." | 1.36 | Predictors of acute postoperative pain after elective surgery. ( de Rijke, JM; Geurts, JW; Gramke, HF; Kessels, AG; Marcus, MA; Patijn, J; Peters, ML; Sommer, M; van Kleef, M, 2010) |
| "Postoperative pain was extremely statistically significant in those cases that had strangulation before operation (P < 0." | 1.35 | Indirect inguinal hernia in Nigerian older children and young adults: is herniorrhaphy necessary? ( Irowa, OO; Osifo, OD, 2008) |
| " prodrug of acetaminophen (propacetamol) in neonates after repeat dosing are reported, with scant data for i." | 1.35 | I.V. acetaminophen pharmacokinetics in neonates after multiple doses. ( Anderson, BJ; Atkins, M; Chalkiadis, GA; Culnane, TJ; Hunt, RW; McNally, CM; Palmer, GM; Perkins, EJ; Smith, KR, 2008) |
| " Therefore, even if traces of opioids are absorbed into the mother's milk, the doses will be very small and the infant's oral bioavailability at this time is likely to be low." | 1.35 | [Do women with Caesarean section have to choose between pain relief and breastfeeding?]. ( Breivik, H; Hestenes, S; Høymork, SC; Løland, BF; Nylander, G; Rosseland, LA, 2008) |
| "Morphine has demonstrated efficacy in the treatment of acute postoperative pain, yet codeine phosphate is commonly preferred as the standard treatment." | 1.35 | Morphine infusions after pediatric cranial surgery: a retrospective analysis of safety and efficacy. ( Bowen-Roberts, T; Hammond, AM; Kent, SK; Ou, CH; Steinbok, P; Warren, DT, 2008) |
| "Higher intensities of acute postoperative pain are associated with chronic pain development." | 1.35 | Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer. ( Fassoulaki, A; Melemeni, A; Sarantopoulos, C; Staikou, C; Triga, A, 2008) |
| "The mean preoperative and postoperative pain scores of the group at 6 hours, 12 hours, 24 hours and 36 hours were 6." | 1.35 | Multimodal pain management following minimally invasive total knee arthroplasty: an experience in 3-dose parecoxib. ( Tanavalee, A; Thiengwittayaporn, S, 2009) |
| "The opiate tolerance was complicated by tactile hyperalgesia at the site of the surgical wound." | 1.35 | [Acute opiate tolerance and postoperative hyperalgesia after a brief infusion of remifentanil managed with multimodal analgesia]. ( Cortiñas Sáenz, M; Cortiñas Sáenz, ML; Gerónimo Pardo, M; Hernández Vallecillo, MT; Ibarra Martí, ML; Mateo Cerdán, CM, 2008) |
| "The intensity of the postoperative pain was measured on a visual analog scale (VAS); measurements were noted up to 24 hours postop then at one month." | 1.34 | [Can the postoperative pain level be predicted preoperatively?]. ( Blay, M; Boileau, P; Carles, M; Dambreville, A; Hovorka, I, 2007) |
| "Postoperative pain was scored using the Oucher visual analog scale and nausea scored using a five point scale." | 1.33 | An evaluation of pain and postoperative nausea and vomiting following the introduction of guidelines for tonsillectomy. ( Nolan, JA; White, MC, 2005) |
| "The management of postoperative pain has been greatly informed by an increasing understanding of the basic science of pain transmission." | 1.33 | Pre-emptive analgesia and protective premedication. What is the difference? ( Bromley, L, 2006) |
| " These findings suggest that potent nonsteroidal anti-inflammatory agents, such as flunixin, may be useful alternatives to opioid-based agents for the control of acute postoperative pain associated with a minor surgical procedure and highlight the importance of assessing the risk-benefit ratio when selecting analgesics and dosing regimens." | 1.32 | Evaluation of postoperative analgesia in a rat model of incisional pain. ( Martin, WJ; St A Stewart, L, 2003) |
| "Pain, swelling and trismus were the commonest complaints." | 1.31 | Postoperative complaints following impacted mandibular third molar surgery in Ile-Ife, Nigeria. ( Assam, E; Oginni, FO; Ogunbodede, EO; Ugboko, VI, 2002) |
| "The primary purpose of the study was to examine the absorption of acetaminophen by measuring serum and saliva concentrations produced by a standard postoperative acetaminophen dosing regimen and secondary to examine the correlation between saliva and serum concentrations of acetaminophen after rectal and oral dosing." | 1.31 | High-dose rectal and oral acetaminophen in postoperative patients--serum and saliva concentrations. ( Hahn, TW; Lund, C; Mogensen, T; Rasmussen, M; Schouenborg, L, 2000) |
| " A combination of opioids, NSAIDs and paracetamol in order to relieve pain allows both for a significant reduction in the dosage of respective drugs, fewer side effects and an improved pain relief." | 1.31 | [Pharmacotherapy of postoperative pain]. ( Cieniawa, T; Dobrogowski, J; Przeklasa-Muszyńska, A; Wordliczek, J, 2000) |
| " There was no evidence of accumulation leading to supratherapeutic concentrations during this dosing schedule for a mean of approximately 2-3 days." | 1.31 | Pharmacokinetics of rectal paracetamol after repeated dosing in children. ( Eriksen, K; Hahn, TW; Henneberg, SW; Holm-Knudsen, RJ; Rasmussen, M; Rasmussen, SN, 2000) |
| "Seventy (93%) had had postoperative pain." | 1.31 | Treatment of postoperative pain in oral and maxillofacial surgery. ( Coulthard, P; Haywood, D; Jackson-Leech, D; Macfarlane, TV; Pleuvry, BJ; Tai, MA, 2000) |
| "Diclofenac sodium has a significant effect on decreasing the pain associated with swallowing postoperatively and on the general condition of the patient." | 1.31 | Comparative study of diclofenac sodium and paracetamol for treatment of pain after adenotonsillectomy in children. ( Husban, AM; Nawasreh, OO; Tawalbeh, MI, 2001) |
| "A pharmacokinetic dynamic simulation model was used to predict rectal paracetamol dosing schedules which would maintain steady state plasma concentrations of 10-20 mg." | 1.30 | Rectal paracetamol dosing regimens: determination by computer simulation. ( Anderson, BJ; Holford, NH, 1997) |
| "Although the postoperative pain treatment pathway was considered to be improved after better education and communication, in fact the opposite was found." | 1.30 | Compliance in administration of prescribed analgesics. ( Boer, C; de Lange, JJ; Treebus, AN; Zuurmond, WW, 1997) |
| "Ketorolac (K) is a useful addition to lidocaine for i." | 1.30 | The dose-response relationship of ketorolac as a component of intravenous regional anesthesia with lidocaine. ( Gardner, G; Reuben, SS; Steinberg, RB, 1998) |
| "To assess the intensity of postoperative pain after laryngeal surgery for cancer and the efficacy of analgesic injections at fixed hours." | 1.30 | Assessment of postoperative pain after laryngeal surgery for cancer. ( Avan, P; Bazin, JE; Commun, F; Derbal, C; Dubray, C; Eschalier, A; Gilain, L; Mom, T, 1998) |
| " In addition, the most current and efficacious dosage regimen for the rectal administration of acetaminophen (40." | 1.30 | Blocks and other techniques pediatric surgeons can employ to reduce postoperative pain in pediatric patients. ( Broadman, LM, 1999) |
| "Seventy-two cases of pyloric stenosis treated in our institution in the last five years were reviewed in an attempt to determine the need for postoperative analgesia after pyloromyotomy in infants." | 1.30 | An audit of postoperative analgesia after pyloromyotomy. ( Gollow, I; Habre, W; Johnson, C; Schwab, C, 1999) |
| "Postoperative pain was assessed using a visual analog scale (VAS) every 4 hours for 72 hours in the two phases." | 1.30 | Effectiveness of an acute pain service inception in a general hospital. ( Albert, A; Bardiau, FM; Boogaerts, JG; Braeckman, MM; Seidel, L, 1999) |
| "We assessed the quality of assessment and reporting of adverse effects in randomized, double-blind clinical trials of single-dose acetaminophen or ibuprofen compared with placebo in moderate to severe postoperative pain." | 1.30 | Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain. ( Collins, SL; Edwards, JE; McQuay, HJ; Moore, RA, 1999) |
| "Following herniorrhaphy the postoperative pain therapy with acetaminophen seems to be sufficient." | 1.29 | [Pain control with paracetamol following inguinal herniorrhaphy or orchidopexy in childhood]. ( Astfalk, W; Walz, GU; Warth, H, 1994) |
| "A propofol infusion was chosen for anaesthesia to achieve early discharge and to reduce the incidence of postoperative emesis." | 1.29 | Propofol for pulsed dye laser treatments in paediatric outpatients. ( Charest, J; Vischoff, D, 1994) |
| "Morphine was the most frequently administered analgesic." | 1.29 | Postoperative pain management in preverbal children: the prescription and administration of analgesics with and without caudal analgesia. ( Altimier, L; Dick, MJ; Holditch-Davis, D; Lawless, S; Norwood, S, 1994) |
| "Acetaminophen suppositories were administered in subtherapeutic doses and at too large time intervals." | 1.29 | Assessment of nurses' judgement for analgesic requirements of postoperative children. ( Rømsing, J, 1996) |
| "A plan for postoperative pain management in the compromised dental patient may be difficult to select." | 1.29 | Oral analgesics in the compromised dental patient: what are the options? ( Trapp, LD, 1995) |
| " Two moderate respiratory depressions occurred in 1989 due to error in dosage with no consequence for the child." | 1.28 | [Intraoperative and postoperative analgesia in pediatric surgery. 1 years' experience]. ( Charles-Guillard, S; Heloury, Y; Meignier, M; Pannier, M; Ricard, P; Rogez, JM; Zaouter, M, 1990) |
| " However, pain intensity scores indicate that APAP double dose gave less analgesia toward the end of the dosing interval than the standard regimen." | 1.28 | Effects of acetaminophen after bilateral oral surgery: double dose twice daily versus standard dose four times daily. ( Pettersen, N; Skoglund, LA, 1991) |
| "The morphine was administered as a single bolus, following delivery, in doses ranging from 2 to 5 mg." | 1.28 | Epidural morphine for analgesia after caesarean section: a report of 4880 patients. ( Douglas, MJ; Fuller, JG; McMorland, GH; Palmer, L, 1990) |
| "Propacetamol was insufficient for the pain in 23% of the cases but one subsequent injection of morphine was always sufficient to calm the child." | 1.28 | [Treatment of postoperative pain in children in the recovery room. Use of morphine and propacetamol by the intravenous route]. ( Cavellat, M; Granry, JC; Lepoittevin, L; Monrigal, JP; Rod, B, 1989) |
| "Ibuprofen 400 mg was consistently more effective than aspirin 650 mg, acetaminophen 600 mg, and both aspirin and acetaminophen when combined with codeine 60 mg." | 1.27 | Five studies on ibuprofen for postsurgical dental pain. ( Cooper, SA, 1984) |
| "Baclofen was not statistically superior to placebo at any one of the four hourly measurements." | 1.27 | Is baclofen an analgesic? ( Fromm, GH; Potter, DM; Terrence, CF, 1983) |
| "A strong interrelation between postoperative pain and trismus indicates pain as the main reason for reduced mouth opening after removal of impacted mandibular third molars." | 1.27 | Interrelation of complaints after removal of impacted mandibular third molars. ( Pedersen, A, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 128 (7.85) | 18.7374 |
| 1990's | 218 (13.37) | 18.2507 |
| 2000's | 369 (22.64) | 29.6817 |
| 2010's | 627 (38.47) | 24.3611 |
| 2020's | 288 (17.67) | 2.80 |
| Authors | Studies |
|---|---|
| Ackermann, R | 1 |
| Cohen, AS | 1 |
| Malizard, R | 1 |
| Meignier, M | 1 |
| Zaouter, M | 1 |
| Ricard, P | 1 |
| Charles-Guillard, S | 1 |
| Heloury, Y | 1 |
| Rogez, JM | 1 |
| Pannier, M | 1 |
| Zhu, CY | 1 |
| Schumm, MA | 1 |
| Hu, TX | 1 |
| Nguyen, DT | 1 |
| Kim, J | 1 |
| Tseng, CH | 1 |
| Lin, AY | 1 |
| Yeh, MW | 1 |
| Livhits, MJ | 1 |
| Wu, JX | 1 |
| Dahm, V | 1 |
| Lui, JT | 1 |
| Chen, JM | 1 |
| Kiss, A | 1 |
| Hamour, AF | 1 |
| Le, TN | 1 |
| Lin, VY | 1 |
| Subramaniam, K | 1 |
| Esper, SA | 1 |
| Mallikarjun, K | 1 |
| Dickson, A | 1 |
| Ruppert DrPH, K | 1 |
| Drabek, T | 1 |
| Wong, H | 1 |
| Holder-Murray, J | 1 |
| Marchesi, N | 1 |
| Govoni, S | 1 |
| Allegri, M | 1 |
| Ferguson, MC | 2 |
| Schumann, R | 4 |
| Gallagher, S | 1 |
| McNicol, ED | 4 |
| Ali, S | 1 |
| Manaloor, R | 1 |
| Johnson, DW | 1 |
| Rosychuk, RJ | 1 |
| LeMay, S | 1 |
| Carleton, B | 1 |
| McGrath, PJ | 2 |
| Drendel, AL | 1 |
| Hosseini, H | 1 |
| Shariatmadari, M | 1 |
| Ayatollahi, V | 4 |
| Vaziribozorg, S | 3 |
| Meybodian, M | 1 |
| Sacha, CR | 1 |
| Mortimer, R | 1 |
| Hariton, E | 1 |
| James, K | 1 |
| Hosseini, A | 1 |
| Gray, M | 2 |
| Xuan, C | 2 |
| Hammer, K | 1 |
| Lange, A | 1 |
| Mahalingaiah, S | 1 |
| Wang, J | 3 |
| Petrozza, JC | 1 |
| Murphy, V | 1 |
| Koea, J | 1 |
| Srinivasa, S | 1 |
| Nishimura, F | 1 |
| Ushijima, T | 1 |
| Nojima, M | 1 |
| Hamada, S | 1 |
| Hara, K | 2 |
| Hamada, Y | 1 |
| Kadowaki, D | 1 |
| Miyamura, S | 1 |
| Oniki, K | 1 |
| Saruwatari, J | 1 |
| Ebada, MA | 1 |
| Ali, AS | 1 |
| Elshakankiry, A | 1 |
| Essa, T | 1 |
| Khater, AG | 1 |
| Hossam, M | 1 |
| Al-Shami, H | 1 |
| Bahbah, EI | 1 |
| Ghaith, HS | 1 |
| Kanmounye, US | 1 |
| Negida, A | 1 |
| Lyngstad, G | 2 |
| Skjelbred, P | 10 |
| Swanson, DM | 2 |
| Skoglund, LA | 16 |
| Luo, MS | 1 |
| Huang, GJ | 1 |
| Cao, Q | 1 |
| Fan, C | 1 |
| Yuan, R | 1 |
| Dong, H | 1 |
| Zhang, S | 1 |
| Meng, H | 1 |
| Ali, H | 1 |
| Perveen, B | 1 |
| Jenkin, DE | 1 |
| Naylor, JM | 1 |
| Descallar, J | 1 |
| Harris, IA | 1 |
| Lubis, AM | 1 |
| Maruanaya, S | 1 |
| Tantri, AR | 1 |
| Pontoh, LAP | 1 |
| Ifran, NNPPS | 1 |
| Hickey, T | 1 |
| Abelleira, A | 1 |
| Acampora, G | 1 |
| Becker, WC | 1 |
| Falker, CG | 1 |
| Nazario, M | 1 |
| Weimer, MB | 1 |
| Watson, H | 1 |
| Hildebolt, C | 1 |
| Rowland, K | 1 |
| Cooper, SA | 17 |
| Desjardins, PJ | 7 |
| Bertoch, T | 2 |
| Paredes-Diaz, A | 2 |
| Troullos, E | 2 |
| Tajaddini, A | 1 |
| Centofanti, R | 1 |
| An, R | 1 |
| Morella, D | 1 |
| La Monaca, G | 2 |
| Pranno, N | 2 |
| Annibali, S | 2 |
| Polimeni, A | 1 |
| Pompa, G | 1 |
| Vozza, I | 1 |
| Cristalli, MP | 2 |
| Patel, AK | 1 |
| Gai, J | 1 |
| Trujillo-Rivera, E | 1 |
| Faruqe, F | 1 |
| Kim, D | 1 |
| Bost, JE | 1 |
| Pollack, MM | 1 |
| Saini, AT | 1 |
| Jiang, ZY | 1 |
| Starr, NC | 1 |
| Talmadge, J | 1 |
| Schmale, I | 1 |
| Radabaugh, P | 1 |
| Yao, WC | 1 |
| Luong, AU | 1 |
| Citardi, MJ | 2 |
| Gasbjerg, KS | 2 |
| Hägi-Pedersen, D | 9 |
| Lunn, TH | 3 |
| Laursen, CC | 1 |
| Holmqvist, M | 1 |
| Vinstrup, LØ | 1 |
| Ammitzboell, M | 1 |
| Jakobsen, K | 2 |
| Jensen, MS | 1 |
| Pallesen, MJ | 1 |
| Bagger, J | 1 |
| Lindholm, P | 4 |
| Pedersen, NA | 4 |
| Schrøder, HM | 4 |
| Lindberg-Larsen, M | 3 |
| Nørskov, AK | 2 |
| Thybo, KH | 9 |
| Brorson, S | 3 |
| Overgaard, S | 8 |
| Jakobsen, JC | 7 |
| Mathiesen, O | 21 |
| Levin, D | 2 |
| Acquadro, M | 1 |
| Cerasuolo, J | 1 |
| Gerges, F | 1 |
| Landes, EK | 1 |
| Leucht, P | 1 |
| Tejwani, NC | 1 |
| Ganta, A | 1 |
| McLaurin, TM | 1 |
| Lyon, TR | 1 |
| Konda, SR | 1 |
| Egol, KA | 1 |
| Sartini, I | 1 |
| Łebkowska-Wieruszewska, B | 1 |
| Gajda, A | 1 |
| Pietruk, K | 1 |
| Gbylik-Sikorska, M | 1 |
| Lisowski, A | 1 |
| Kim, TW | 1 |
| Poapolathep, A | 1 |
| Giorgi, M | 1 |
| Lalonde, DH | 2 |
| Lalonde, JF | 1 |
| MacDermid, JC | 1 |
| Chung, KC | 1 |
| Gan, BS | 1 |
| Mierisch, C | 1 |
| Van Demark, RE | 1 |
| Luc, M | 1 |
| Gabriel, I | 1 |
| Abdalian, T | 1 |
| Minassian, VA | 1 |
| Tomic, J | 1 |
| Wallner, J | 1 |
| Mischak, I | 1 |
| Sendlhofer, G | 1 |
| Zemann, W | 1 |
| Schanbacher, M | 1 |
| Hassanzadeh, H | 1 |
| Sandner-Kiesling, A | 1 |
| Payer, M | 1 |
| Zrnc, TA | 1 |
| Erten, O | 1 |
| Isiktas, G | 1 |
| Avci, SN | 1 |
| Berber, E | 1 |
| Song, Q | 1 |
| Xue, FS | 1 |
| Xiao, YG | 1 |
| Tian, T | 1 |
| Lee, CH | 1 |
| Jeong, GM | 1 |
| Yip, W | 1 |
| Chen, AB | 1 |
| Malekyan, C | 1 |
| Widjaja, W | 1 |
| Yan, K | 1 |
| Stankey, M | 1 |
| Sun, X | 1 |
| Ashrafi, AN | 1 |
| Graham, JN | 1 |
| Dickerson, SC | 1 |
| Eloustaz, MH | 1 |
| Desai, MM | 1 |
| Gill, IS | 1 |
| Aron, M | 1 |
| Kim, MP | 2 |
| Wilson, SH | 2 |
| Wilson, PR | 1 |
| Bridges, KH | 1 |
| Bell, LH | 1 |
| Clark, CA | 1 |
| DeVitis, J | 1 |
| Flom, E | 1 |
| Cooper-Roth, T | 1 |
| Davis, A | 1 |
| Krech, L | 1 |
| Fisk, C | 1 |
| Pounders, S | 1 |
| Kwazneski, D | 1 |
| Chapman, A | 1 |
| Valdez, C | 1 |
| Vilai, P | 1 |
| Dhanachanvisith, N | 1 |
| Kongmalai, P | 1 |
| Gettis, M | 1 |
| Brown, AM | 1 |
| Fujimoto, A | 1 |
| Wetzel, M | 1 |
| Thomsen, J | 1 |
| Shafeeq, H | 1 |
| DiGiacomo, JC | 1 |
| Sookraj, KA | 1 |
| Gerber, N | 1 |
| Bahr, A | 1 |
| Talreja, ON | 1 |
| Munnangi, S | 1 |
| Cardozo-Stolberg, S | 1 |
| Angus, LDG | 1 |
| DeMaio, EL | 1 |
| Hunnicutt, JL | 1 |
| Haley, RM | 1 |
| Nazzal, E | 1 |
| Chen, Y | 2 |
| Premkumar, A | 1 |
| Lamplot, JD | 1 |
| Samady, HA | 1 |
| Gottschalk, MB | 1 |
| Xerogeanes, JW | 1 |
| Rafiei, M | 1 |
| Afsahi, M | 1 |
| Karbalaeikhani, A | 1 |
| Kheradmand, B | 1 |
| Hazrati, E | 1 |
| Sun, LY | 1 |
| Gitman, M | 1 |
| Malik, A | 1 |
| Te Terry, PL | 1 |
| Spiro, M | 1 |
| Raptis, DA | 1 |
| Ramsay, M | 1 |
| Felder, L | 2 |
| Cao, CD | 1 |
| Konys, C | 1 |
| Weerasooriya, N | 1 |
| Mercier, R | 1 |
| Berghella, V | 2 |
| Dayaratna, S | 1 |
| Ucar, M | 1 |
| Erdogan, MA | 1 |
| Sanlı, M | 2 |
| Colak, YZ | 1 |
| Aydogan, MS | 1 |
| Yucel, A | 1 |
| Ozgul, U | 2 |
| Sadri, L | 1 |
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| Mejia-Sierra, L | 1 |
| Lam, Q | 1 |
| Heilman, JG | 1 |
| Balchander, D | 1 |
| Noonan, K | 1 |
| Pineda, DM | 1 |
| O'Loughlin, E | 1 |
| Peng, YG | 1 |
| Cheaib, A | 1 |
| Chan, MTV | 1 |
| Williams, R | 1 |
| Vavolizza, RD | 1 |
| Grabski, DF | 1 |
| Roecker, Z | 1 |
| Swanson, JR | 1 |
| McGahren, ED | 1 |
| Gander, JW | 1 |
| Freo, U | 1 |
| Yano, K | 2 |
| Muto, M | 1 |
| Nagai, T | 1 |
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| Kedoin, C | 1 |
| Nagano, A | 1 |
| Matsui, M | 1 |
| Murakami, M | 1 |
| Sugita, K | 1 |
| Onishi, S | 1 |
| Yamada, K | 1 |
| Yamada, W | 1 |
| Matsukubo, M | 1 |
| Kaji, T | 1 |
| Ieiri, S | 1 |
| Forkin, KT | 1 |
| Mitchell, RD | 1 |
| Chiao, SS | 1 |
| Song, C | 1 |
| Chronister, BNC | 1 |
| Wang, XQ | 1 |
| Chisholm, CA | 1 |
| Tiouririne, M | 1 |
| Passias, BJ | 1 |
| Johnson, DB | 2 |
| Schuette, HB | 1 |
| Secic, M | 1 |
| Heilbronner, B | 1 |
| Hyland, SJ | 1 |
| Sager, A | 1 |
| Cho, JSH | 1 |
| McCarthy, K | 1 |
| Schiavo, S | 1 |
| Jacob, B | 1 |
| Engelsakis, M | 1 |
| Zywiel, M | 1 |
| Karkouti, K | 1 |
| McCluskey, S | 1 |
| Clarke, H | 2 |
| Wong, J | 3 |
| Monisha, N | 1 |
| Poomalar, GK | 1 |
| Goodchild, JH | 1 |
| Donaldson, M | 1 |
| Gill, C | 1 |
| Giuliano, K | 1 |
| Lee, GC | 1 |
| Berkowitz, R | 1 |
| Hacker, S | 1 |
| Hu, J | 3 |
| Rechter, A | 1 |
| Dahl, ME | 1 |
| McDonald, KC | 1 |
| Brown, O | 1 |
| Halder, G | 1 |
| Crouss, T | 1 |
| Pan, C | 2 |
| Eckhardt, S | 1 |
| Hoover, M | 1 |
| Dancz, CE | 1 |
| Bercu, C | 1 |
| Hemal, A | 1 |
| Badlani, G | 1 |
| Dutta, R | 1 |
| Pathak, R | 1 |
| Cordray, H | 1 |
| Alfonso, K | 1 |
| Brown, C | 1 |
| Evans, S | 2 |
| Goudy, S | 1 |
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| Landry, AM | 1 |
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| Shahravan, A | 1 |
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| McGwin, G | 1 |
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| Feinstein, J | 2 |
| Momaya, A | 1 |
| Ponce, B | 1 |
| Brabston, E | 1 |
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| Caparlar, CO | 1 |
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| Raeder, J | 4 |
| Semyonov, M | 1 |
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| Cohen, N | 1 |
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| Friger, M | 1 |
| Acker, A | 1 |
| Geftler, A | 1 |
| Zlotnik, A | 1 |
| Brotfain, E | 1 |
| Patzkowski, JC | 1 |
| Patzkowski, MS | 1 |
| Steiness, J | 4 |
| Graungaard, BK | 2 |
| Lundstrom, LH | 1 |
| Bieder, MJ | 2 |
| Beck, T | 2 |
| Skettrup, M | 2 |
| von Cappeln, AG | 2 |
| Gazendam, A | 1 |
| Ekhtiari, S | 1 |
| Horner, NS | 1 |
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| de Sa, DL | 1 |
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| Ayeni, OR | 1 |
| Abo Elfadl, GM | 1 |
| AbdelRady, MM | 1 |
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| Ali, WN | 1 |
| Feng, H | 1 |
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| Abdelwahab, EH | 1 |
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| Morosanu, B | 1 |
| Stanculea, I | 1 |
| Coman, A | 1 |
| Stoian, A | 1 |
| Bubenek-Turconi, SI | 1 |
| Commesso, EA | 1 |
| Osazuwa-Peters, N | 1 |
| Frank-Ito, DO | 1 |
| Einhorn, L | 1 |
| Ji, KSY | 1 |
| Greene, NH | 1 |
| Eapen, RJ | 1 |
| Raynor, EM | 1 |
| Shnayder, Y | 1 |
| Baumanis, MM | 1 |
| Brown, A | 1 |
| Reese, A | 1 |
| Bur, AM | 1 |
| Kakarala, K | 1 |
| Sykes, KJ | 1 |
| Bjørnholdt, KT | 2 |
| Brix, LD | 1 |
| Archer, V | 3 |
| Cloutier, Z | 3 |
| Park, L | 3 |
| Briatico, D | 4 |
| Walton, JM | 4 |
| Halepas, S | 1 |
| Christiansen, C | 1 |
| Koch, A | 1 |
| Aziz, SR | 1 |
| Shafer, DM | 1 |
| Ferneini, EM | 1 |
| Lundstrøm, LH | 1 |
| Varnum, C | 1 |
| Pleckaitiene, L | 1 |
| Anker Pedersen, N | 1 |
| Torres, CM | 1 |
| Geneslaw, AS | 1 |
| Svoboda, L | 1 |
| Smerling, AJ | 1 |
| Schlosser Metitiri, KR | 1 |
| Shakir, FTZ | 1 |
| Sultan, R | 1 |
| Siddiqui, R | 1 |
| Shah, MZ | 1 |
| Javed, A | 1 |
| Jamal, A | 1 |
| Miroshnychenko, A | 1 |
| Ibrahim, S | 1 |
| Azab, M | 1 |
| Roldan, Y | 1 |
| Martinez, JPD | 1 |
| Tamilselvan, D | 1 |
| He, L | 2 |
| Little, JW | 1 |
| Urquhart, O | 1 |
| Tampi, M | 1 |
| Polk, DE | 1 |
| Moore, PA | 8 |
| Hersh, EV | 6 |
| Claytor, B | 1 |
| Carrasco-Labra, A | 2 |
| Brignardello-Petersen, R | 3 |
| Stessel, B | 2 |
| Lambrechts, M | 1 |
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| Vanderstappen, C | 1 |
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| Ory, JP | 2 |
| Herbots, J | 1 |
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| Vaninbroukx, M | 1 |
| Van de Velde, M | 8 |
| Creighton, EW | 1 |
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| Jelly, CA | 1 |
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| Shotwell, ME | 1 |
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| Stevenson, KL | 1 |
| Stein, MK | 1 |
| Fryhofer, GW | 1 |
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| Mehta, S | 3 |
| Kinoshita, M | 1 |
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| Marchisio, PG | 1 |
| Vezzoli, C | 1 |
| Zampogna, S | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Randomized Controlled Trial for Postoperative opt-in Narcotic Treatment in Outpatient Endocrine Surgery[NCT04710069] | 102 participants (Actual) | Interventional | 2020-06-26 | Completed | |||
| Role of Scheduled Intravenous Acetaminophen for Postoperative Pain Management in an Enhanced Recovery After Surgery (ERAS) Population: A Prospective, Randomized, Double-Blind and Placebo-Controlled Clinical Trial[NCT03198871] | Phase 4 | 180 participants (Actual) | Interventional | 2018-05-24 | Completed | ||
| Maxigesic IV Bunionectomy Study- A Phase 3, Randomized, Double-Blind, Multiple-Dose, Parallel-Group and Placebo-Controlled Study[NCT02689063] | Phase 3 | 276 participants (Actual) | Interventional | 2016-10-26 | Completed | ||
| Assessing Efficacy of Intravenous Acetaminophen for Perioperative Pain Control for Oocyte Retrieval: a Randomized, Double Blind, Placebo-controlled Trial[NCT03073980] | Phase 4 | 161 participants (Actual) | Interventional | 2019-09-01 | Completed | ||
| Analgesic Effect of Ibuprofen 400, 600 and 800 mg, Paracetamol 500 and 1000 mg, and Paracetamol 1000 mg Plus 60 mg Codeine: Single-dose, Randomized, Placebo-controlled and Double-blind Study on Acute Pain After Third Molar Surgery[NCT00699114] | Phase 4 | 350 participants (Anticipated) | Interventional | 2007-06-30 | Completed | ||
| Comparison of Analgesic Effects of Gabapentin and Paracetamol in Patients With Hand Injury[NCT04068506] | Phase 4 | 68 participants (Actual) | Interventional | 2019-09-01 | Completed | ||
| A Randomized, Double-Blind, Placebo-Controlled Trial to Compare the Analgesic Efficacy and Safety of Naproxen Sodium Tablets and Hydrocodone/Acetaminophen Tablets in Postsurgical Dental Pain[NCT04307940] | Phase 4 | 221 participants (Actual) | Interventional | 2020-03-12 | Completed | ||
| Comparative Analgesic Effects of Preoperative Administration of Paracetamol (Acetominophen) 500 mg Plus Codeine 30 mg and Ibuprofen 400 mg on Pain After Third Molar Surgery[NCT04730297] | Phase 4 | 120 participants (Actual) | Interventional | 2018-01-01 | Completed | ||
| Dexamethasone Twice for Pain Treatment of Total Knee Arthroplasty - A Randomized Blinded Placebo-controlled Clinical Trial[NCT03506789] | Phase 4 | 485 participants (Actual) | Interventional | 2018-09-14 | Completed | ||
| A Randomized, Controlled Trial Comparing Combination Therapy of Ibuprofen + Acetaminophen Versus Hydrocodone + Acetaminophen for the Treatment of Pain After Carpal Tunnel Surgery[NCT01974609] | Phase 4 | 347 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| Gabapentin Premedication for Pediatric Anterior Cruciate Ligament Reconstruction: Randomized Control Trial[NCT03417479] | 57 participants (Actual) | Observational | 2015-10-09 | Completed | |||
| The Effect of Cryoneurolysis for the Treatment of Acute Postoperative Pain Following Total Knee Arthroplasty in High Pain Responders - A Randomized, Participant- and Observer-masked, Sham-controlled Trial[NCT06088602] | 44 participants (Anticipated) | Interventional | 2023-11-30 | Not yet recruiting | |||
| Morphine-sparing Effect of Intravenous Paracetamol for Post-operative Pain Management Following Laparoscopic Gastric Banding in Morbidly Obese Patients[NCT02154464] | 220 participants (Anticipated) | Interventional | 2014-06-30 | Not yet recruiting | |||
| Effect of Combinations of Paracetamol, Ibuprofen, and Dexamethasone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty. The RECIPE Randomized Clinical Trial[NCT04123873] | Phase 4 | 1,060 participants (Actual) | Interventional | 2020-03-05 | Completed | ||
| Non-Opioid Prescriptions After Arthroscopic Surgery in Canada (NO PAin): A Randomized Controlled Trial[NCT04566250] | 200 participants (Actual) | Interventional | 2021-02-24 | Completed | |||
| NOL-Guided Superficial Parasternal Intercostal Plane Block Versus Erector Spinae Plane Block in Open Heart Surgery With Cardiopulmonary Bypass - A Propensity Matched Non-Inferiority Clinical Trial[NCT06070701] | 60 participants (Anticipated) | Interventional | 2023-06-01 | Recruiting | |||
| Pericapsular Nerve Group (PENG) Block and Lateral Femoral Cutaneous Nerve (LFCN) Block Versus Fascia Iliaca (FIC) Block for Multimodal Analgesia After Total Hip Replacement Surgery: a Retrospective Analysis[NCT05916209] | 60 participants (Actual) | Observational | 2023-02-01 | Completed | |||
| Study of the Laryngopharyngeal Symptoms After Minimally Invasive Thyroidectomy: Comparison Between the Protector Laryngeal Mask Airway and the Endotracheal Tube.[NCT03098667] | 79 participants (Actual) | Interventional | 2017-02-01 | Completed | |||
| A Randomized, Placebo Controlled, Multi-Center Study of the Efficacy, Pharmacokinetics (PK) and Pharmacodynamics (PD) of IV Acetaminophen for the Treatment of Acute Pain in Pediatric Patients[NCT01635101] | Phase 3 | 197 participants (Actual) | Interventional | 2012-06-30 | Completed | ||
| Evaluation of the Effect of Ultrasonographic Guided Erector Spina Plan Block Application on Postoperative Analgesia in Infants Undergoing Laparotomy[NCT04875390] | 40 participants (Actual) | Interventional | 2021-05-10 | Completed | |||
| Comparison of Analgesic Efficacy of Sacral erectOR Spinae Plane Block and Caudal Block in Patients Undergoing Hypospadias Surgery[NCT05632536] | 68 participants (Actual) | Interventional | 2022-12-21 | Completed | |||
| Comparative Efficacy of Intravenous Acetaminophen vs. Oral Acetaminophen in Ambulatory Surgery[NCT03558555] | Phase 4 | 103 participants (Actual) | Interventional | 2017-12-08 | Completed | ||
| Preemptive Oral vs Intravenous Acetominophen for Postoperative Pain in Minimally Invasive Gynecologic Surgery: A Randomized Control Trial[NCT03391284] | 75 participants (Actual) | Interventional | 2016-02-29 | Completed | |||
| Randomized Trial of Bupivacaine as Adjuvant for Post-operative Pain in Mohs Micrographic Surgery[NCT04362566] | Phase 4 | 174 participants (Actual) | Interventional | 2020-07-30 | Completed | ||
| Post-operative Pain Control With Acetaminophen and Ibuprofen After Functional Endoscopic Sinus Surgery for Chronic Rhinosinusitis: a Prospective Study.[NCT05287217] | 60 participants (Anticipated) | Interventional | 2022-07-29 | Not yet recruiting | |||
| The Effect of Sphenopalatine Ganglion Block on the Postoperative Pain in Patients Undergoing Septorhinoplasty[NCT04020393] | 42 participants (Actual) | Observational | 2019-01-10 | Completed | |||
| Assessing Perceived Quality of Care With Differing Pain Management Protocols After Outpatient Otolaryngology Procedures[NCT04976387] | Phase 3 | 150 participants (Actual) | Interventional | 2021-07-02 | Completed | ||
| Double Blinded Randomized Placebo Controlled Study in Evaluating the Effectiveness of IV Acetaminophen for Acute Post Operative Pain in C-Section Patients[NCT02069184] | Phase 4 | 66 participants (Actual) | Interventional | 2013-11-30 | Completed | ||
| Opioid-Free Intravenous Anesthesia for Patients With Joint Hypermobility Syndrome Undergoing Craneo-Cervical Fixation: A Case-series Study Focused on Anti-hyperalgesic Approach[NCT04437589] | 42 participants (Actual) | Observational | 2018-09-06 | Completed | |||
| Intravenous Lignocaine as an Analgesic Adjunct in Adolescent Idiopathic Scoliosis Surgery (IGNITE-AIS Study)[NCT04931433] | Phase 4 | 102 participants (Anticipated) | Interventional | 2020-12-24 | Recruiting | ||
| A Double-Blind Randomized Placebo-Controlled Clinical Trial of Preoperative Gabapentin Prior to Vaginal Apical Suspension Prolapse Procedures[NCT05658887] | Phase 4 | 110 participants (Anticipated) | Interventional | 2023-01-01 | Enrolling by invitation | ||
| Single Dose Preoperative Gabapentin Use in Minimally Invasive Hysterectomy for Acute Pain Management[NCT02703259] | Phase 4 | 137 participants (Actual) | Interventional | 2016-06-30 | Completed | ||
| EVALUATION OF THE EFFICACY OF NOVEL IBUPROFEN ACETAMINOPHEN COMBINATION FORMULATIONS IN THE TREATMENT OF POST-SURGICAL DENTAL PAIN[NCT01559259] | Phase 2 | 394 participants (Actual) | Interventional | 2012-04-10 | Completed | ||
| Effect of Intravenous Acetaminophen on Postoperative Opioid-related Complications[NCT02156154] | Phase 3 | 580 participants (Actual) | Interventional | 2014-12-31 | Completed | ||
| Comparison of the Effect of Propacetamol, Ibuprofen or Their Combination on Postoperative Pain and Quality of Recovery After Laparoscopic Hernia Repair in Children[NCT03352362] | 159 participants (Actual) | Interventional | 2017-12-15 | Completed | |||
| Comparing Protocols for Analgesia Following Elective Cesarean Section[NCT03622489] | Phase 4 | 120 participants (Anticipated) | Interventional | 2017-03-01 | Recruiting | ||
| Effect of Submucosal Dexamethasone on Postoperative Pain, Swelling and Trismus After Periodontal Surgery: Randomized Clinical Study[NCT06119893] | 25 participants (Actual) | Interventional | 2021-08-12 | Completed | |||
| Comparison of the Analgesic Effects of Scalp Nerve Block and Intravenous Ibuprofen Applications Under the Guidance of Nociception Level Index (NoL) in Patients Undergoing Elective Supratentorial Craniotomy[NCT05763836] | Phase 4 | 102 participants (Anticipated) | Interventional | 2022-11-01 | Recruiting | ||
| Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery[NCT03959969] | 48 participants (Actual) | Interventional | 2019-07-17 | Completed | |||
| A Randomized Controlled Study Evaluating Suprainguinal Fascia Iliaca Compartment Block in Direct Anterior Approach to Total Hip Arthroplasty - A Pilot Study[NCT05237479] | 0 participants (Actual) | Interventional | 2022-06-30 | Withdrawn (stopped due to Study never approved by IRB or initiated) | |||
| Modified Pre-operative Oral Doses Acetaminophen Versus Intravenous Acetaminophen[NCT02994940] | Phase 4 | 74 participants (Actual) | Interventional | 2017-08-28 | Completed | ||
| Multi-institutional, Randomized Controlled Trial Assessing Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery[NCT03783702] | Phase 4 | 118 participants (Actual) | Interventional | 2019-04-04 | Completed | ||
| Efficacy of Preoperative Administration of Paracetamol-codeine on Pain Following Impacted Mandibular Third Molar Surgery: a Randomized, Split-mouth, Placebo-controller, Double-blind Clinical Trial[NCT03049878] | Phase 4 | 32 participants (Actual) | Interventional | 2013-02-21 | Completed | ||
| Randomized Control Trial of IV Acetaminophen for Post Cesarean Delivery Pain Relief[NCT02046382] | Phase 4 | 132 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Comparison Between USG-Guided Infiltration Popliteal Artery Capsule Knee Block Versus Adductor Canal Block Application as Postoperative Analgesia in Total Knee Prosthesis Under General Anesthesia: Randomized Clinical Trial[NCT05956275] | Phase 4 | 20 participants (Actual) | Interventional | 2020-12-08 | Completed | ||
| A Double Blind, Randomized, Placebo-controlled Study to Investigate the Effectiveness of IV Acetominophen Administered During Functional Endoscopic Sinus Surgery in Reducing the Use of Opiates to Treat Postoperative Pain[NCT01608308] | 62 participants (Actual) | Interventional | 2012-07-31 | Completed | |||
| The Effect of a Non-Opioid Multimodal Pain (NOMO) Protocol in Decreasing Narcotic Use After Urogynecologic Surgery[NCT05386069] | Phase 3 | 11 participants (Actual) | Interventional | 2019-11-15 | Completed | ||
| Nurses' Knowledge and Attitudes Towards Opioids in Pain Management in North Cyprus[NCT04252443] | 127 participants (Actual) | Interventional | 2018-06-01 | Completed | |||
| Does Bilateral Continuous Peri Operative Erector Spinae Plane Block Improve The Enhanced Recovery Program After Open Heart Surgeries in Adults?[NCT04506762] | 20 participants (Actual) | Interventional | 2020-11-01 | Terminated (stopped due to Surgical team resigned from our hospital) | |||
| Efficacy of Transversus Abdominis Plane (TAP) Block Techniques: A Comparison Between Intraoperative Surgeon Administration by Direct Visualization vs Image Guided Administration by Anesthesiologist, a Prospective Randomized Controlled Trial[NCT03577912] | 60 participants (Actual) | Interventional | 2015-08-17 | Completed | |||
| Postoperative Narcotic Use After Laparoscopic Gynecologic Surgery: A Randomized, Double-blind, Placebo-controlled Trial Comparing Continuous Intraperitoneal Infusion of Ropivacaine Versus Saline for Post-operative Pain Control[NCT04118777] | 0 participants (Actual) | Interventional | 2020-05-01 | Withdrawn (stopped due to Misregistered to wrong sponsor.) | |||
| Use of Intravenous Acetaminophen in Adolescents and Pediatrics Undergoing Spinal Fusion Surgery: Randomized Controlled Trial[NCT04959591] | Phase 3 | 99 participants (Actual) | Interventional | 2021-06-01 | Completed | ||
| A Single Institutional Randomized Controlled Trial for A Multimodal Enhanced Recovery Program in Anorectal Surgery[NCT03992079] | 60 participants (Actual) | Interventional | 2019-06-20 | Terminated (stopped due to PI is no longer at institution) | |||
| Psychosocial and Psychophysical Factors Influencing the Effect of Preemptive Systemic Analgesia in Combination With Regional Anesthesia on Postoperative Pain Following Upper Limb Surgery[NCT05248152] | 90 participants (Anticipated) | Interventional | 2022-01-13 | Recruiting | |||
| Evaluation of Perioperative Usage of Ketorolac on Postoperative Pain Reduction in Pediatric Patients With Adenotonsillectom[NCT05074056] | Phase 4 | 200 participants (Anticipated) | Interventional | 2022-02-08 | Recruiting | ||
| Randomized, Controlled Trial of Post-operative Steroids and Pain Control After Tonsillectomy[NCT03995628] | Phase 2 | 150 participants (Anticipated) | Interventional | 2018-12-18 | Recruiting | ||
| Postoperative Ibuprofen Use and Risk of Bleeding in Pediatric Tonsillectomy[NCT03385057] | Phase 1 | 0 participants (Actual) | Interventional | 2018-09-30 | Withdrawn (stopped due to Study design flaws; research design needed to be reconfigured) | ||
| Assessing the Efficacy of Intravenous Acetaminophen Versus the Oral Formulation for Perioperative Pain Treatment[NCT02216682] | 174 participants (Anticipated) | Observational | 2014-08-31 | Not yet recruiting | |||
| Efficacy of Different Doses of Pregabalin as a Multimodal Analgesic Agent in Postoperative Pain Control After Total Knee Arthroplasty - A Randomized Controlled Trial[NCT05447364] | Phase 4 | 82 participants (Anticipated) | Interventional | 2021-07-01 | Recruiting | ||
| Transcutaneous Electrical Nerve Stimulation (TENS) for Pain Alleviation in Perioperative Fracture Patients[NCT04209673] | 50 participants (Anticipated) | Observational | 2020-01-06 | Recruiting | |||
| Randomized Clinical Trial of Non-Opioid Pain Medications After Adenotonsillectomy[NCT03618823] | Phase 1/Phase 2 | 268 participants (Actual) | Interventional | 2018-10-25 | Terminated (stopped due to Early termination due to COVID-19 cases and cancelled surgeries.) | ||
| Use of a Non-Opioid Pain Regimen for Post-Operative Analgesia Following Intracapsular Adenotonsillectomy[NCT04791761] | Phase 1/Phase 2 | 300 participants (Anticipated) | Interventional | 2021-04-13 | Recruiting | ||
| A Randomized Study of Codeine Plus Paracetamol Versus Placebo for PRK Post-operative Pain[NCT02625753] | Phase 3 | 40 participants (Actual) | Interventional | 2014-11-30 | Completed | ||
| PAracetamol and NSAID in Combination: A Randomised, Blinded, Parallel, 4-group Clinical Trial[NCT02571361] | Phase 4 | 556 participants (Actual) | Interventional | 2015-11-30 | Completed | ||
| Optimization of Opioid Discharge Prescriptions Following Thyroid and Parathyroid Surgeries[NCT04955444] | 240 participants (Actual) | Interventional | 2021-06-14 | Completed | |||
| Use of Single Dose Pre-Operative Pregabalin for Post-Operative Analgesia in Bilateral Head and Neck Cancer Surgery: A Randomized, Double-Blinded, Placebo-Controlled Trial[NCT03714867] | Phase 4 | 0 participants (Actual) | Interventional | 2019-03-22 | Withdrawn (stopped due to Inability to recruit patients) | ||
| Effect of the Peri-incisional Multimodal Cocktail Infiltration on Postcraniotomy Headache[NCT03915639] | 100 participants (Anticipated) | Interventional | 2022-04-30 | Not yet recruiting | |||
| The Opioid-Sparing and Analgesic Effects of IV Acetaminophen in Craniotomy: A Prospective, Randomized, Placebo-Controlled, Double-Blind Study[NCT01598701] | Phase 4 | 100 participants (Actual) | Interventional | 2012-05-02 | Completed | ||
| Pre-emptive Topical Lidocaine 5% Plaster for Prevention of Post-craniotomy Pain : a Protocol for a Randomized, Triple Blind, Placebo-controlled Trail[NCT04169854] | Phase 3 | 180 participants (Anticipated) | Interventional | 2020-10-15 | Recruiting | ||
| Standardization of Post-operative Opiate Prescriptions for Same-day Ankle and Wrist Fracture Surgeries[NCT05322564] | 100 participants (Anticipated) | Interventional | 2022-05-31 | Not yet recruiting | |||
| Relieving Acute Pain (RAP): A Pilot Study[NCT03426137] | Phase 2 | 3 participants (Actual) | Interventional | 2018-09-17 | Terminated (stopped due to The focus of the project has shifted to publishing a protocol for future trials because we were unable to recruit. Three participants signed the consent forms but withdrew before the randomization.) | ||
| Efficiency And Quality In Post-Surgical Pain Therapy After Discharge[NCT05221866] | 711 participants (Actual) | Interventional | 2022-03-14 | Completed | |||
| Using Difference-in-Differences to Evaluate the Effect of a Statewide Quality Improvement Program on New Persistent Opioid Use After Surgery[NCT04805229] | 30,000 participants (Actual) | Observational | 2013-01-01 | Completed | |||
| U.S Guided Erector Spinae Block for Postoperative Pain Control in Patients Undergoing Para Umblical Hernial Repair. (Comparative Study ).[NCT06120088] | 300 participants (Anticipated) | Observational | 2023-12-01 | Not yet recruiting | |||
| Preoperative Cesarean Section Intravenous Acetaminophen and Postoperative Pain Control: A Blinded Randomized Placebo-Controlled Trial[NCT02694653] | Phase 1 | 200 participants (Anticipated) | Interventional | 2014-10-31 | Enrolling by invitation | ||
| Impact of Counseling and Education on Opioid Consumption After Anterior Cruciate Ligament Reconstruction: A Randomized Controlled Trial[NCT04885231] | 80 participants (Anticipated) | Interventional | 2021-05-12 | Active, not recruiting | |||
| Liposomal Bupivacaine Reduces Opiate Consumption After Rotator Cuff Repair in a Randomized Control Trial[NCT03692546] | 50 participants (Actual) | Interventional | 2017-02-01 | Completed | |||
| LIBERATE - LIposomal Bupivacaine vERsus Adjuncts in Total shouldErs: A Randomized Controlled Trial of Injection at the Brachial Plexus[NCT03887650] | Phase 4 | 90 participants (Actual) | Interventional | 2019-03-11 | Completed | ||
| Increased Postoperative Opioid Use is a Risk Factor for an Ileus After Laparoscopic Colorectal Surgery---A Case Control Study[NCT05262569] | 596 participants (Actual) | Observational | 2022-04-01 | Completed | |||
| Post-operative Course of Dexamethasone to Reduce Tonsillectomy Morbidity[NCT04879823] | Phase 3 | 300 participants (Anticipated) | Interventional | 2021-08-05 | Recruiting | ||
| Clinical Outcomes of an Adductor Canal Block Versus Liposomal Bupivacaine in Total Knee Arthroplasty Patients: A Randomized Prospective Study[NCT04086186] | Phase 4 | 60 participants (Actual) | Interventional | 2017-03-22 | Completed | ||
| Ultrasound Guided Suprainguinal Fascia Iliaca Block vs. Periarticular Injection for Total Knee Arthroplasty: Prospective Randomized Study[NCT05636449] | 70 participants (Actual) | Interventional | 2022-11-25 | Completed | |||
| [NCT01948505] | Phase 4 | 210 participants (Actual) | Interventional | 2013-08-31 | Completed | ||
| The Impact of Using Enhanced Recovery After Surgery Approach on Orthognathic Surgery Outcome: A Historical Cohort Study[NCT04596774] | 90 participants (Actual) | Observational | 2018-08-01 | Completed | |||
| Erector Spinae Plane Block Versus Intrapleural Intercostal Plane Block for Post-thoracotomy Pain: a Randomized Trial[NCT04013815] | 60 participants (Actual) | Interventional | 2019-08-01 | Completed | |||
| Ropivacaine Plasma Concentrations and Pharmacokinetics Following Erector Spinae Plane Block in the Pediatric Population[NCT04298099] | Phase 4 | 24 participants (Anticipated) | Interventional | 2020-12-17 | Recruiting | ||
| Errector Spinae Plane Block for Postoperative Pain Management in Cardiac Surgery: A Randomized Controlled Trial[NCT04420104] | 40 participants (Anticipated) | Interventional | 2020-06-01 | Recruiting | |||
| Effects of Erector Spinae Plane Block on Sympathectomy in Off Pump Coronary Artery Bypass Surgery[NCT04447560] | 25 participants (Actual) | Interventional | 2020-07-06 | Completed | |||
| Erector Spinae Plane Block in Patients Undergoing Minimally Invasive Lumbar Spine Surgery: A Randomized Controlled Trial[NCT05856539] | 48 participants (Anticipated) | Interventional | 2023-05-15 | Recruiting | |||
| Intraoperative Surgeon Administered Transversus Abdominis Plan (TAP) Block With Liposomal Bupivacaine and Post-operative Pain Control After Repeat Cesarean Delivery[NCT05393908] | 40 participants (Anticipated) | Interventional | 2024-01-01 | Not yet recruiting | |||
| Maxigesic 325 Acute Dental Pain Study: A Double-blind, Placebo-controlled, Randomized, Parallel Group Comparison of the Effects of Maxigesic 325 Versus Acetaminophen, Ibuprofen and Placebo in Participants With Acute Dental Pain[NCT01420653] | Phase 3 | 408 participants (Actual) | Interventional | 2013-04-30 | Completed | ||
| Preoperative Melatonin to Decrease Analgesia Usage After Third Molar Surgery[NCT04791943] | Phase 2 | 60 participants (Anticipated) | Interventional | 2021-05-12 | Recruiting | ||
| Organisation PERiopératoire de l'anesthésie et de la Chirurgie Ambulatoire[NCT02380430] | 2,174 participants (Actual) | Observational | 2014-04-30 | Completed | |||
| Comparison of Lidocaine, Dexmedetomidine and Ketamine in Multimodal Analgesia Management Following Sleeve Gastrectomy Surgery: A Randomized Double-Blind Trial[NCT04836819] | 78 participants (Actual) | Interventional | 2021-04-08 | Completed | |||
| Comparison of Intravenous Ibuprofen and Erector Spinae Plane Block for Postoperative Pain Management After Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study[NCT04232072] | 0 participants (Actual) | Interventional | 2020-02-11 | Withdrawn (stopped due to no participants) | |||
| Pain Reduction and Changes in Upper Limb Function Produced by Physiotherapy, Ibuprofen Arginine, Gabapentin and the Absence of Treatment, in Carpal Tunnel Syndrome[NCT04025203] | Phase 4 | 80 participants (Anticipated) | Interventional | 2019-08-01 | Recruiting | ||
| Pain Reduction and Changes in Upper Limb Function Produced by Over the Counter Oral Ibuprofen Versus the Lack of Treatment, in Carpal Tunnel Syndrome.[NCT04328805] | Phase 4 | 45 participants (Anticipated) | Interventional | 2020-09-30 | Not yet recruiting | ||
| Pain Reduction Produced by Physiotherapy, Ibuprofen, and the Absence of Treatment, in Carpal Tunnel Syndrome[NCT04119739] | Phase 4 | 74 participants (Anticipated) | Interventional | 2020-04-14 | Not yet recruiting | ||
| Intravenous Versus Oral Acetaminophen for Postoperative Pain Control After Cesarean Delivery[NCT02487303] | 148 participants (Actual) | Interventional | 2015-03-17 | Completed | |||
| The Impact of IV Acetaminophen on Postoperative Pain in Women Undergoing Pelvic Organ Prolapse Repair: A Double-Blind Randomized Placebo Controlled Trial[NCT02155738] | Phase 4 | 204 participants (Actual) | Interventional | 2014-07-31 | Completed | ||
| The Impact of Tamsulosin on Duration of Post-Operative Urinary Retention in Women Undergoing Pelvic Reconstructive Surgery- A Double Blind, Randomized, Placebo-Controlled Study[NCT04597372] | Phase 2 | 154 participants (Anticipated) | Interventional | 2021-11-03 | Recruiting | ||
| Prospective, Randomized, Controlled Trial of an Opiate Sparing Protocol Versus Standard Opiate Based Protocol Following Open Reduction Internal Fixation of Distal Radius Fractures[NCT05215236] | 72 participants (Anticipated) | Interventional | 2022-03-01 | Enrolling by invitation | |||
| Achieving Peri-Operative Pain Control Without Opioids[NCT04813991] | Phase 3 | 0 participants (Actual) | Interventional | 2022-03-15 | Withdrawn (stopped due to Enrollment was never initiated and the PI is leaving the institution so the study is closing.) | ||
| Analgesic Efficacy of Oral Dexketoprofen Trometamol/Tramadol Hydrochloride Versus Tramadol Hydrochloride/Paracetamol: a Randomised, Double-blind, Placebo and Active-controlled, Parallel Group Study in Moderate to Severe Acute Pain After Removal of Impacte[NCT02777970] | Phase 4 | 654 participants (Actual) | Interventional | 2016-04-30 | Completed | ||
| Oxycodone or Ibuprofen for Suspected Isolated Forearm Fractures in Pediatric Patients: A Randomized Noninferiority Trial[NCT04523623] | 200 participants (Anticipated) | Interventional | 2020-09-30 | Not yet recruiting | |||
| Multimodal Pain Management for Cesarean Delivery: A Randomized Control Trial[NCT02922985] | Phase 4 | 120 participants (Actual) | Interventional | 2016-10-31 | Completed | ||
| Quadratus Lumborum Block for Total Abdominal Hysterectomy: a Double-blind, Randomized, Controlled Trial[NCT05765318] | 72 participants (Anticipated) | Interventional | 2023-02-27 | Recruiting | |||
| Effect of 24 mg Dexamethasone Preoperatively on Surgical Stress, Pain and Recovery in Robotic-assisted Laparoscopic Hysterectomy[NCT04762381] | 100 participants (Anticipated) | Interventional | 2022-06-01 | Recruiting | |||
| Prospective, Controlled Versus Placebo, Randomized, Double-blind Study, Evaluating the Value of Non-opioid Analgesic Combination (Based on Paracetamol, Nefopam, Ketoprofen) for Postoperative Analgesia.[NCT01882530] | Phase 4 | 223 participants (Actual) | Interventional | 2013-07-23 | Terminated (stopped due to Practice on postoperative pain management changed) | ||
| Opioid-Free Versus Transitional Anesthetic With Opioids From Tonsillectomy[NCT04528173] | Phase 4 | 550 participants (Anticipated) | Interventional | 2020-07-22 | Recruiting | ||
| Postoperative Ibuprofen and the Risk of Bleeding After Tonsillectomy With or Without Adenoidectomy[NCT01605903] | Phase 2 | 741 participants (Actual) | Interventional | 2012-05-03 | Completed | ||
| The Effectiveness Of Intravenous Ibuprofen Versus Intravenous Ketorolac For Postoperative Pain Relief After Cesarean Section[NCT05907993] | Phase 4 | 50 participants (Actual) | Interventional | 2023-02-01 | Active, not recruiting | ||
| Postoperative Analgesic Efficacy of Ultrasound-guided Para-sartorial Compartment Block in Knee Surgery: A Randomized Study[NCT05566561] | 60 participants (Anticipated) | Interventional | 2022-10-19 | Recruiting | |||
| Postoperative Analgesic Efficacy of Local Infiltration Analgesia Versus Adductor Canal Block After Anterior Cruciate Ligament Reconstruction: A Randomised Controlled Double-blinded Trial[NCT02524652] | Phase 4 | 104 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| Analgesic Efficacy of IPACK Versus Selective Tibial Nerve Block in Patients Scheduled for Anterior Cruciate Ligament Reconstruction Under General Anaesthesia With an Adductor Canal Block: a Randomized Controlled Double-blinded Trial[NCT05303233] | 80 participants (Anticipated) | Interventional | 2022-05-01 | Recruiting | |||
| A Prospective Pilot Study of a Non-Narcotic Post-Operative Course After Colectomy[NCT05200806] | Phase 4 | 25 participants (Anticipated) | Interventional | 2022-02-07 | Recruiting | ||
| STandard Versus No Opioid Prescription After Prolapse and Anti-INcontinence Surgery: A Randomized Controlled, Non-inferiority Trial[NCT04491617] | 148 participants (Actual) | Interventional | 2020-08-27 | Completed | |||
| ICE-T Postoperative Multimodal Pain Regimen Compared to the Standard Regimen in Same Day Vaginal Pelvic Reconstructive Surgery: a Randomized Controlled Trial[NCT03052816] | Phase 4 | 66 participants (Actual) | Interventional | 2017-04-01 | Completed | ||
| Randomised Surgical Intervention Study Between Adenotonsillectomy and Adenotonsillotomy in Children With Obstructive Sleep Apnea Syndrome[NCT01676181] | 79 participants (Actual) | Interventional | 2011-11-30 | Completed | |||
| Multiple Doses of Gabapentin and Postoperative Morphine Consumption in Total Knee Arthroplasty[NCT01307202] | 101 participants (Actual) | Interventional | 2007-10-31 | Completed | |||
| Does Single Dose Dexmedetomidine for Procedural Sedation Reduce Post-operative Pain in Total Knee Arthroplasty? A Randomized Control Study[NCT02466022] | Phase 3 | 54 participants (Actual) | Interventional | 2015-06-30 | Completed | ||
| An Open-Label Pilot Study of the Analgesic Efficacy and Safety Of Q8003 and of the Conversion From IV Morphine PCA Analgesia to Q8003 or to Percocet® in Patients Who Have Undergone Primary Unilateral Total Knee Arthroplasty or Total Hip Arthroplasty[NCT00818493] | Phase 2 | 44 participants (Actual) | Interventional | 2009-02-28 | Completed | ||
| Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients[NCT02160301] | Phase 4 | 0 participants (Actual) | Interventional | 2017-11-30 | Withdrawn (stopped due to Insufficient infrastructure/funding for enrollment) | ||
| Synergistic Effect Of Parenteral Diclofenac And Paracetamol In The Pain Management Of Acute Limb Injuries[NCT04199572] | Phase 4 | 162 participants (Actual) | Interventional | 2022-10-16 | Completed | ||
| Pre-Emptive Analgesia in Ano-Rectal Surgery[NCT02402543] | 90 participants (Actual) | Interventional | 2014-06-30 | Completed | |||
| The Effect of Intravenous Paracetamol in Combination With NSAIDs for Postoperative Pain in Children[NCT02248493] | Phase 4 | 54 participants (Actual) | Interventional | 2012-11-30 | Completed | ||
| Comparison of Tramadol vs. Tramadol With Paracetamol for Efficacy of Postoperative Pain Management in Lumbar Discectomy: A Randomised Controlled Trial[NCT03482492] | 60 participants (Actual) | Interventional | 2014-03-20 | Completed | |||
| A Prospective Randomized Double Blind Trial to Assess the Effect of a Single Preoperative Dose of Gabapentin on Postoperative Opioid Consumption in Patients Undergoing Rhinoplasty[NCT03498261] | Phase 1 | 50 participants (Actual) | Interventional | 2018-01-30 | Active, not recruiting | ||
| Erector Spinae Plane Block in Lumbar Spinal Fusion : Double-blind, Randomized Controlled Trial.[NCT04904575] | 130 participants (Anticipated) | Interventional | 2022-01-03 | Recruiting | |||
| Erector Spinae Plane Block in Lumbar Release Surgery : Double-blind, Randomized Controlled Trial[NCT04925882] | 100 participants (Actual) | Interventional | 2022-01-03 | Completed | |||
| Effects of Intra-Operative Ropivaciane Epidural Injection on Post-Operative Outcomes Following Elective Lumbar Fusion[NCT03035656] | Phase 4 | 228 participants (Anticipated) | Interventional | 2019-03-01 | Not yet recruiting | ||
| UControlPain App (This is the Official IRB Title)[NCT03833648] | 60 participants (Actual) | Interventional | 2019-06-19 | Completed | |||
| Effect of Paracetamol and Ibuprofen When Intravenously Given Combination or Alone in Reducing Morphine Requirements After Total Knee Arthroplasty[NCT04414995] | Phase 2/Phase 3 | 36 participants (Actual) | Interventional | 2020-06-05 | Completed | ||
| Comparison of the Effect of Intra-articular Administration of 2% Ropivacaine vs. 7.5% Ropivacaine as an Analgesic in the Immediate Postoperative Period of Knee Arthroscopy in Acute Injuries at the ABC Medical Center[NCT05807945] | Phase 4 | 68 participants (Actual) | Interventional | 2020-04-01 | Completed | ||
| Opiate Free Multimodal Pain Pathway in Elective Foot and Ankle Surgery: A Prospective Study[NCT04771741] | 72 participants (Actual) | Observational | 2020-12-01 | Completed | |||
| Demonstration of OTC Naproxen Sodium's (Aleve's) Anti-inflammatory Action in Dental Implant Surgery Patients[NCT04694300] | Phase 4 | 32 participants (Actual) | Interventional | 2021-02-07 | Completed | ||
| Transmuscular Quadratus Lumborum Block for Postoperative Pain After Total Abdominal Hysterectomy[NCT02586454] | 64 participants (Actual) | Interventional | 2015-11-30 | Completed | |||
| Ultrasound-guided Quadratus Lumborum Block Versus Transversus Abdominis Plane Block in Children Undergoing Laparoscopic Appendicectomy: A Randomized Clinical Study[NCT04031196] | 34 participants (Actual) | Interventional | 2018-10-01 | Completed | |||
| Quadratus Lumborum Nerve Blocks in Laparoscopic Myomectomy Patients[NCT03935815] | Phase 1 | 26 participants (Actual) | Interventional | 2019-05-01 | Terminated (stopped due to Closed prior to completion secondary to surgeon leaving UCLA) | ||
| Comparison of Ultrasound Guided Quadratus Lumborum Block With Ultrasound Guided TAP Block for Postoperative Analgesia After Laparoscopic Nephrectomy: a Prospective Randomized Controlled Trial[NCT02824939] | 96 participants (Actual) | Interventional | 2016-09-30 | Completed | |||
| The Efficacy of Ultrasound Guided Continuous Quadratus Lumborum Block Versus Continuous Paravertebral Block In Radical Cystectomy[NCT03547011] | 60 participants (Actual) | Interventional | 2017-09-16 | Completed | |||
| A Randomized Controlled Trial Comparing Quadratus Lumborum Block and Paravertebral Block for Postoperative Analgesia in Laparoscopic Hepatectomy and Open Hepatectomy[NCT03540537] | 180 participants (Anticipated) | Interventional | 2018-05-09 | Recruiting | |||
| Effects of Lavender Oil on Postoperative Pain, Sleep Quality and Mood[NCT03093454] | Phase 3 | 58 participants (Actual) | Interventional | 2017-10-27 | Completed | ||
| Aromatherapy for Post-operative Anxiety and Pain After Primary Unilateral Total Knee Replacement: A Pilot Randomized Controlled Trial[NCT06045078] | 30 participants (Anticipated) | Interventional | 2023-10-03 | Recruiting | |||
| The Effect of Aromatic Solution Applied After Percutaneous Nephrolithotomy Surgery on Sore Throat, Thirst and Nausea-Vomiting[NCT05522023] | 105 participants (Actual) | Interventional | 2021-02-15 | Completed | |||
| The Use of Lavender Aromatherapy to Decrease Women's Anxiety and Perception of Pain During Multi-channel Urodynamics Procedure[NCT02344745] | 80 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| [NCT03016650] | Phase 4 | 80 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | ||
| A Study to Compare the Analgesic Efficacy of Two Different Paracetamol Doses as Measured by Post-operative Dental Pain Relief[NCT01082081] | Phase 4 | 300 participants (Actual) | Interventional | 2009-10-31 | Completed | ||
| A Study to Compare the Analgesic Efficacy of Two Different Paracetamol Doses as Measured by Post-operative Pain Relief[NCT01075243] | Phase 4 | 401 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Comparing Narcotic vs. Non-narcotic Pain Regimens After Pediatric Appendectomy: A Randomized Controlled Trial[NCT03528343] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2017-09-05 | Withdrawn (stopped due to Lost research support for enrolling patients) | ||
| ROPIVACAINE WITH CLONIDINE FOR PEDIATRIC RECTUS SHEATH BLOCKS- THE MAGIC COMBINATION? - A Double Blinded Prospective Study[NCT02439281] | 50 participants (Actual) | Interventional | 2015-05-31 | Terminated (stopped due to The patients were discharged on the day of the surgery.) | |||
| A Randomized, Double-blinded, Placebo-controlled Study of Ketorolac Use in Pediatric Patients Undergoing Tonsillectomy[NCT03453541] | Phase 4 | 600 participants (Anticipated) | Interventional | 2017-11-21 | Recruiting | ||
| The Evaluation of Pre-incisional and Post-closure Local Anesthetic vs. Normal Saline on Postoperative Pain in Pediatric Appendectomies[NCT02483689] | 100 participants (Anticipated) | Interventional | 2015-08-31 | Recruiting | |||
| The Median Effective Dose (ED50) of Paracetamol and Morphine for Postoperative Patients: A Study of Interaction.[NCT01366313] | 90 participants (Actual) | Interventional | 2007-09-30 | Completed | |||
| Opioid-Free Shoulder Arthroplasty[NCT03540030] | Phase 4 | 86 participants (Actual) | Interventional | 2016-09-30 | Completed | ||
| Efficacy and Side Effects of Intrathecal Morphine in Multimodal Analgesia for Unilateral Total Knee Arthroplasty[NCT03232957] | 131 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| A Prospective, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial Evaluating the Use of Perioperative Intravenous Lidocaine Infusion to Decrease Pain Scores and Opioid Consumption After Robotic-Assisted Prostatectomy and Robotic-Assisted Partia[NCT03824808] | Phase 4 | 21 participants (Actual) | Interventional | 2019-02-26 | Terminated (stopped due to Challenges with recruitment of surgical research subjects in the target population.) | ||
| THE EFFECT OF ULTRASOUND GUIDED RECTUS SHEATH BLOCK ON POSTOPERATIVE ANALGESIA AND URETHRAL CATHETER PAIN IN ROBOTIC PROSTATECTOMY OPERATIONS: A PROSPECTIVE RANDOMIZED CONTROLLED TRIAL[NCT05242198] | 60 participants (Actual) | Interventional | 2022-03-15 | Completed | |||
| Ultrasound Guided External Oblique Intercostal Plane Block vs. Transversus Abdominis Plane Block for Laparoscopic Cholecystectomy: Prospective Randomized Study[NCT05632991] | 80 participants (Anticipated) | Interventional | 2022-12-01 | Recruiting | |||
| A Comparison of Analgesic and Respiratory Effects From Tapentadol Versus Oxycodone After Laparoscopic Hysterectomy.[NCT03314792] | Phase 4 | 86 participants (Actual) | Interventional | 2017-12-04 | Completed | ||
| A Double-blind, Randomized, Placebo-controlled Phase IV Clinical Study of the Efficacy and Safety of a New Formulation of Paracetamol for the Management of Fever of Infectious Origin[NCT02283203] | Phase 4 | 80 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| Single-dose and Multi-dose Open-label Pilot Trial of the Analgesic Efficacy and Tolerability of Intranasal Ketorolac Tromethamine (SPRIX®) in Dental Implant Surgery Patients With Postoperative Pain.[NCT01490931] | Phase 4 | 28 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| Multimodal Opiate-sparing Analgesia Versus Traditional Opiate Based Analgesia After Cardiac Surgery, a Randomized Controlled Trial[NCT01966172] | Phase 4 | 180 participants (Actual) | Interventional | 2007-03-31 | Completed | ||
| Comparing Pain Outcomes of Intra-operative IV Tylenol and/or IV Toradol Administration for Carpal Tunnel Release and Distal Radius Fracture Surgeries[NCT02313675] | Phase 4 | 44 participants (Actual) | Interventional | 2015-05-31 | Completed | ||
| Efficacy of Intravenous Acetaminophen as Analgesic Adjuvant Therapy in Children Undergoing Posterior Fossa Surgery[NCT02532322] | Phase 2 | 0 participants (Actual) | Interventional | 2015-11-30 | Withdrawn (stopped due to not enough patients meeting criteria) | ||
| A Randomized, Double-Blinded, Placebo Controlled Trial Using Single Dose Dexmedetomidine In The Treatment Of Pain In Patients Undergoing Cleft Palate Repair[NCT02915042] | Phase 4 | 0 participants (Actual) | Interventional | 2017-12-31 | Withdrawn (stopped due to Recruitment concerns) | ||
| High Dose Dexamethasone as Pain Treatment After Arthroscopic Shoulder Surgery: A Randomised, Blinded Clinical Trial[NCT01414569] | Phase 4 | 97 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| Efficacy of Intra-operative Subacromial Corticosteroid Injections on Surgical Outcomes After Arthroscopic Shoulder Surgery[NCT02867904] | Phase 4 | 12 participants (Actual) | Interventional | 2016-03-31 | Terminated (stopped due to It was difficult to recruit patients to get the appropriate sample size.) | ||
| Early Post-op. Viscosupplementation After Primary Anterior Cruciate Ligament (ACL) Reconstruction: a Randomized, Placebo Controlled Trial[NCT02630407] | Phase 4 | 60 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| A Phase 3 Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Evaluation of the Safety and Analgesic Efficacy of COV795 in Moderate to Severe Post-Operative Bunionectomy Pain Followed by an Open-Label Extension[NCT01484652] | Phase 3 | 329 participants (Actual) | Interventional | 2011-11-30 | Completed | ||
| Evaluation of Honey as Adjunct Therapy to Tylenol and Motrin in Treating Post-Operative Pain and Nausea Following Tonsillectomy[NCT03931395] | 230 participants (Actual) | Interventional | 2019-04-16 | Completed | |||
| Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy[NCT05024825] | Phase 4 | 17 participants (Actual) | Interventional | 2017-08-04 | Terminated (stopped due to recruitment target not met.) | ||
| Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?[NCT05025228] | 170 participants (Actual) | Observational | 2019-06-01 | Completed | |||
| A Randomized, Active-Controlled, Parallel Group, Double-Blind Study to Compare the Efficacy and Safety of Tramadol HCl/Acetaminophen ER and IR in Subjects Who Complain of Moderate to Severe Postoperative Pain[NCT01814878] | Phase 3 | 320 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| Effect of Ultrasound Guided Bilateral Thoracolumbar Interfascial Plane (TLIP) Block on Post-operative Opioid Consumption After Lumbar Spine Surgeries. A Randomized Double Blinded Study.[NCT03193658] | 34 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| Evaluation of Post-operative Pain in Bascom Cleft Lift Operation Receiving Multimodal Analgesia and Spinal Saddle Block in Day Case Surgery Setting.[NCT02196727] | 32 participants (Actual) | Observational [Patient Registry] | 2013-05-31 | Completed | |||
| The Effect of Preoperative Steroids Injection on Pain and Oedema After Total Knee Arthroplasty . A Double -Blinded Randomized Controlled Study.[NCT04084912] | Phase 3 | 86 participants (Anticipated) | Interventional | 2020-01-01 | Not yet recruiting | ||
| Efficacy of Steroids on Functional Outcomes After Musculoskeletal Injuries of the Hand[NCT05003596] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2021-09-01 | Not yet recruiting | ||
| A Prospective Randomized Double-blind Placebo Controlled Trial; Does Pre and Postoperative Dextromethorphan Reduce Post-tonsillectomy Pain in Children?[NCT02727491] | Phase 4 | 85 participants (Actual) | Interventional | 2012-03-31 | Completed | ||
| Investigating the Safety of Morphine and Ibuprofen in Children Post-adenotonsillectomy for Obstructive Sleep Apnea[NCT01680939] | Phase 3 | 120 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | ||
| Clonidine for Tourniquet-related Pain in Children: A Pilot Study[NCT04564430] | Phase 4 | 20 participants (Anticipated) | Interventional | 2021-03-01 | Recruiting | ||
| Effectiveness of a Combined Acetaminophen and Ibuprofen Regimen for Management of Post-Tonsillectomy Pain in Pediatric Patients[NCT04551196] | Phase 3 | 47 participants (Actual) | Interventional | 2020-09-28 | Completed | ||
| Intravenous Acetaminophen Versus Saline in Postoperative Analgesia After Laparoscopic Hysterectomy: A Randomized, Double Blind, Placebo Controlled Trial[NCT02400580] | Phase 4 | 183 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| The Effectiveness of IV/PO Acetaminophen in the Perioperative Period in Reducing Opiate Use After Lumbar Spine Fusion: a Prospective, Randomized Controlled Trial[NCT03104816] | Phase 4 | 28 participants (Actual) | Interventional | 2016-10-31 | Terminated (stopped due to Could not get an approval from Department Reviewer for the study continuation.) | ||
| Perioperative Regular Usage of Propacetamol to Reduce Post Cesarean Section Uterine Contraction Pain and Opioid Consumption[NCT03878082] | 100 participants (Actual) | Interventional | 2019-08-12 | Completed | |||
| Implementation of ERAS Protocol for Cesarean Delivery in Clinical Center Vojvodina[NCT04058444] | 200 participants (Anticipated) | Interventional | 2019-09-19 | Recruiting | |||
| Video-based, Patient-Focused Opioid Education in the Perioperative Period: A Feasibility Study[NCT03986866] | 110 participants (Actual) | Interventional | 2019-04-29 | Completed | |||
| The Effect of Dexamethasone in Combination With Paracetamol and Ibuprofen as Adjuvant, Postoperative Pain After Herniated Disc Surgery[NCT01953978] | Phase 4 | 160 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| The Analgesic Efficacy of Continuous Sub-fascial Bupivacaine Infusion and Lidocaine Patches in Post-cesarean Patients With Opiate Use Disorder: A Comparative Efficacy Analysis[NCT04033562] | Phase 4 | 2 participants (Actual) | Interventional | 2020-01-15 | Terminated (stopped due to limited enrollment and unable to enroll subjects to reach statistical significance) | ||
| Efficacy of a Single-shot Wound Infiltration With Bupivacaine/Adrenalin During Cesarean Section in Reducing Postoperative Pain. A Randomized Prospective Controlled Trial[NCT03395912] | 288 participants (Actual) | Interventional | 2018-01-25 | Completed | |||
| Ultrasound Guided Quadratus Lumborum Block Versus Erector Spinae Plane Block For Postoperative Analgesia In Patient Undergoing Laparoscopic Hysterectomy: A Randomized Double Blinded Study[NCT05465525] | 81 participants (Actual) | Interventional | 2022-07-25 | Completed | |||
| Ultrasound Guided Quadratus Lumborum Block Versus Erector Spinae Plane Block For Postoperative Analgesia In Patient Undergoing Abdominal Hysterectomy: A Randomized Double Blinded Study[NCT05675657] | 81 participants (Actual) | Interventional | 2023-01-15 | Completed | |||
| Assessment of Postoperative Pain After Using Two Formulations of Calcium Hydroxide Intracanal Medication : A Randomized Clinical Trial.[NCT05021809] | Phase 4 | 60 participants (Anticipated) | Interventional | 2021-07-25 | Recruiting | ||
| Efficacy of Continuous Wound Infusion in Major Lumbar and Thoracic Spine Surgery : A Randomised, Double-blinded, Placebo-controlled Study[NCT01743794] | Phase 2/Phase 3 | 60 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| The Efficacy of Intraoperative Parecoxib Combined With Paracetamol for Reducing Opioid Consumption in Patients Undergoing Breast Cancer Surgery Under General Anesthesia: A Prospective Randomized Controlled Trial[NCT05757388] | 60 participants (Anticipated) | Interventional | 2023-03-28 | Recruiting | |||
| Efficacy of Pain Control Following Root Canal Treatment Using Paracetamol Alone and in Combination With Three Different Non-Steroidal Anti-Inflammatory Analgesics[NCT02417337] | Phase 2 | 170 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Effect of Preoperative, Single-dose Diclofenac Potassium on Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis: A Double Blind Randomized Controlled Trial[NCT03341260] | Phase 2/Phase 3 | 70 participants (Actual) | Interventional | 2016-12-31 | Completed | ||
| Paragastric Lesser Omentum Neural Block to Prevent Visceral Pain After Laparoscopic Sleeve Gastrectomy: A Randomized Clinical Trial Protocol.[NCT05353426] | 145 participants (Actual) | Interventional | 2021-08-13 | Completed | |||
| The Effect of Timing of Intravenous Paracetamol Administration on Post-surgical Pain and Cytokines Levels Following Laparoscopic Sleeve Gastrectomy[NCT03221998] | Early Phase 1 | 126 participants (Anticipated) | Interventional | 2017-07-31 | Not yet recruiting | ||
| Effect of Unilateral Ultrasound-Guided Subcostal Transversus Abdominis Plane Block in Patients Undergoing Laparoscopic Sleeve Gastrectomy[NCT03856788] | Phase 4 | 43 participants (Actual) | Interventional | 2018-12-10 | Completed | ||
| Postoperative Pain After Laparoscopic Sleeve Gastrectomy: Comparison of Isolated Intravenous Analgesia, Epidural Analgesia Associated With Analgesia iv and Port-sites Infiltration With Bupivacaine Associated With Analgesia iv[NCT02662660] | Phase 3 | 147 participants (Actual) | Interventional | 2012-01-31 | Completed | ||
| Randomized Placebo Controlled Trial of Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair[NCT02992028] | Phase 4 | 54 participants (Anticipated) | Interventional | 2016-12-31 | Recruiting | ||
| Perioperative Use of Celecoxib to Improve Pain Control in Patients Undergoing Tonsillectomy: a Randomized, Double Blind, Placebo-controlled Trial[NCT00583453] | Phase 2 | 18 participants (Actual) | Interventional | 2007-10-31 | Completed | ||
| Pre-emptive Effect of Duloxetine in the Second Knee in Staged Total Knee Arthroplasty: A Randomized Controlled Study[NCT03792828] | Phase 4 | 90 participants (Anticipated) | Interventional | 2019-01-31 | Not yet recruiting | ||
| Perioperative Duloxetine for Pain Management After Laparoscopic Hysterectomy: A Prospective Randomized Placebo-controlled Study[NCT03350334] | 100 participants (Actual) | Interventional | 2017-12-04 | Completed | |||
| Effect of Transversus Abdominis Plane (TAP) Block as Postoperative Pain Management After Laparoscopic Colon Surgery[NCT01418144] | Phase 4 | 80 participants (Actual) | Interventional | 2010-08-31 | Completed | ||
| Erector Spinae Plane Block Versus Transverse Abdominis Plane Block in Laparoscopic Hysterectomy[NCT04003987] | Phase 3 | 78 participants (Actual) | Interventional | 2019-05-01 | Completed | ||
| Randomized Double-blind Controlled Study to Assess the Efficacy of Intravenous Acetaminophen Associated With Strong Opioids in the Management of Acute Pain in Adult Cancer Patients[NCT04779567] | Phase 4 | 112 participants (Actual) | Interventional | 2019-06-10 | Completed | ||
| Analgesic Duration of Interscalene Block After Outpatient Arthroscopic Shoulder Surgery With Intravenous Dexamethasone, Dexmedetomidine or Their Combination: A Randomized Controlled Trial[NCT03270033] | Phase 4 | 198 participants (Actual) | Interventional | 2017-09-18 | Completed | ||
| Postoperative Analgesia After Cardiac Surgery - A Double-Blind, Prospective and Randomized Comparison of Wound Infiltration With Liposomal Bupivacaine and Bupivacaine Hydrochloride[NCT03270514] | Phase 3 | 60 participants (Actual) | Interventional | 2018-11-15 | Completed | ||
| The Effect of Dexamethasone Versus Local Infiltration Technique on Postoperative Nausea and Vomiting After Tonsillectomy in Children: A Randomized Double-blind Clinical Trial[NCT02355678] | 129 participants (Actual) | Interventional | 2015-01-31 | Completed | |||
| Multimodal Pain Management After Robotic-Assisted Total Laparoscopic Hysterectomy[NCT04429022] | Phase 3 | 68 participants (Actual) | Interventional | 2020-11-24 | Completed | ||
| A Randomized Control Trial Study of the Efficacy of Celecoxib Versus Ketorolac for Perioperative Pain Control[NCT03331315] | Phase 2 | 170 participants (Actual) | Interventional | 2013-09-01 | Completed | ||
| "Postoperative Pain Management in Pediatric Patients With Cerebral Palsy - Comparative Observational Study"[NCT05252650] | 130 participants (Anticipated) | Observational | 2022-02-15 | Recruiting | |||
| Popliteal Block for Postoperative Pain in Knee-ankle Soft Tissue Surgery in Cerebral Palsy[NCT02507700] | 60 participants (Actual) | Interventional | 2015-06-30 | Completed | |||
| Inter-semispinal Plane (ISP) Block for Postoperative Analgesia Following Cervical Spine Surgery: A Prospective Randomized Controlled Trial[NCT06003933] | 50 participants (Actual) | Interventional | 2023-03-03 | Completed | |||
| Non-Steroidal Anti-inflammatory Drugs (NSAIDS) vs. Tramadol in Pain Management After Transnasal Transsphenoidal Surgery Among Patients With Pituitary Adenomas: A Prospective Randomized Controlled Trial[NCT04611685] | 202 participants (Anticipated) | Interventional | 2020-10-31 | Recruiting | |||
| Randomized, Double-Blind, Placebo-Controlled Trial Comparing Opioid-Sparing and Opioid-Containing Analgesia Regimens Following Trans-sphenoidal Surgery for Pituitary Tumors[NCT02351700] | Phase 4 | 62 participants (Actual) | Interventional | 2015-02-01 | Completed | ||
| An Open-label Non-randomized Phase IV Trial of the Clinical Efficacy of Intravenously Administered 1000mg Paracetamol as Antipyretic and Analgesic Medication[NCT01070732] | Phase 4 | 100 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| Comparison of the Efficacy of IV Acetaminophen Versus IV Indomethacin in Treatment of Hemodynamically Significant PDA in VLBW Infants[NCT03537144] | Phase 3 | 37 participants (Actual) | Interventional | 2016-06-30 | Terminated (stopped due to Difficulty enrolling patients) | ||
| The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy: A Prospective, Double Blinded, Placebo Controlled Study[NCT01106547] | Phase 4 | 55 participants (Anticipated) | Interventional | 2009-08-31 | Completed | ||
| Preoperative Use of Pregabalin and Analgesia Levels After Laparoscopic Cholecystectomy[NCT01321801] | 50 participants (Actual) | Interventional | 2009-11-30 | Completed | |||
| Impact of Preemptive Intravenous Ibuprofen on Intraoperative Analgesia in Third Molar Teeth[NCT03170726] | 60 participants (Anticipated) | Interventional | 2017-05-15 | Active, not recruiting | |||
| Ultrasound Guided Transversus Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Colonic Resection- a Double Blind Randomised Controlled Trial[NCT01339273] | 72 participants (Actual) | Interventional | 2011-09-30 | Completed | |||
| ERAS Lazio Network Clinical Registry[NCT03353311] | 1,000 participants (Actual) | Observational [Patient Registry] | 2014-09-01 | Completed | |||
| Assessment of Preemptive Analgesic Effect of Caldolor® vs. Ofirmev® on Third Molar Surgery: A Prospective, Randomized, Double-blinded Clinical Trial[NCT02133326] | Phase 2 | 67 participants (Actual) | Interventional | 2014-03-31 | Active, not recruiting | ||
| Analgesic Effect of Single Dose Intravenous Acetaminophen in Pediatric Patients Undergoing Tonsillectomy[NCT01691690] | Phase 2 | 250 participants (Actual) | Interventional | 2012-10-31 | Completed | ||
| A Randomized Trial Comparing Ibuprofen Plus Acetaminophen Versus Oxycodone Alone After Outpatient Soft Tissue Hand Surgery[NCT03111186] | Phase 2 | 40 participants (Actual) | Interventional | 2017-04-24 | Completed | ||
| Effect of Single Dose of Tramadol on Extubation Response and Quality of Emergence(Cough and Nausea Vomiting) Following Supratentorial Intracranial Surgery[NCT02964416] | Phase 4 | 80 participants (Actual) | Interventional | 2016-03-31 | Completed | ||
| Effects of Pre-emptive Scalp Infiltration With Ropivacaine and Methylprednisolone- Ropivacaine on Pain After Craniotomy in Adults[NCT04078139] | Phase 4 | 188 participants (Anticipated) | Interventional | 2021-03-05 | Not yet recruiting | ||
| Pre-emptive Scalp Infiltration With Dexamethasone Plus Ropivacaine vs. Ropivacaine for Relief of Postoperative Pain After Craniotomy in Adults[NCT03618264] | Phase 4 | 140 participants (Actual) | Interventional | 2019-04-04 | Completed | ||
| Evaluation of the Efficacy of Adding Magnesium Sulfate as an Adjuvant to Bupivacaine in Bilateral Ultrasound Guided Paravertebral Block for Laparoscopic Cholecystectomy[NCT05099250] | 50 participants (Actual) | Interventional | 2019-07-15 | Completed | |||
| Do Peri-operative High Doses of Intravenous Glucocorticoids Improve Short-term Functional Outcome After Direct Anterior Total Hip Arthroplasty? A Randomized, Single Surgeon, Placebo Controlled, Double Blind Study[NCT04317872] | 70 participants (Anticipated) | Interventional | 2020-07-01 | Recruiting | |||
| [NCT01340313] | 72 participants (Actual) | Observational | 2011-03-31 | Completed | |||
| Effects of Addition of Systemic Tramadol or Adjunct Tramadol to Lidocaine Used for Intravenous Regional Anesthesia in Patients Undergoing Hand Surgery[NCT02658721] | Phase 3 | 60 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| Does Magnesium Sulfate as a Supplement in Adductor Canal Blocks Improve Pain Control After Total Knee Arthroplasty?[NCT02581683] | Phase 4 | 130 participants (Actual) | Interventional | 2015-09-30 | Completed | ||
| Multicenter Study to Evaluate the Analgesic Efficacy of XP21L in Subjects With Pain Following Bunionectomy Surgery[NCT00366444] | Phase 3 | 201 participants (Actual) | Interventional | 2006-08-31 | Completed | ||
| The Effect and Contribution of a Perioperative Ketamine Infusion in an Established Enhanced Recovery Pathway[NCT04625283] | Phase 4 | 1,544 participants (Anticipated) | Interventional | 2021-04-12 | Enrolling by invitation | ||
| Multicentre, Double-blind, Placebo-controlled, Randomized, Parallel Group Comparison of the Analgesic Effects of Different Maxigesic Doses Versus Acetaminophen, Ibuprofen and Placebo for the Teeth Extraction Pain[NCT01104844] | Phase 2 | 0 participants (Actual) | Interventional | Withdrawn (stopped due to The study was withdrawn due to administrative reason) | |||
| Home Care Management of Pediatric Pain[NCT00251628] | Phase 4 | 211 participants (Actual) | Interventional | 2000-06-30 | Completed | ||
| Analgesic Effect of IntraPeritoneal LIGNOcaine in Gynaecological Open Surgery: A Double-blinded Randomised Placebo-controlled Trial (IP LIGNO Trial)[NCT05897385] | 112 participants (Anticipated) | Interventional | 2023-08-22 | Recruiting | |||
| Management Of Pain After Cesarean Trial[NCT03929640] | Phase 3 | 49 participants (Actual) | Interventional | 2019-08-05 | Completed | ||
| Efficacy of Combined Ibuprofen and Acetaminophen Therapy Versus Ibuprofen Alone Versus Placebo Alone for Pain of Initial Orthodontic Wire Insertion: a Randomized Controlled Trial[NCT04059172] | Early Phase 1 | 375 participants (Anticipated) | Interventional | 2019-12-10 | Recruiting | ||
| An Open-label, Single-dose, Pharmacokinetic Study of Acetaminophen/Naproxen Sodium Fixed Combination Tablets in Adolescents 12 to <17 Years of Age With Orthodontic Pain[NCT05844995] | Phase 1 | 30 participants (Anticipated) | Interventional | 2023-09-13 | Recruiting | ||
| Oral Ibuprofen Plus Acetaminophen Versus Ibuprofen Alone for Acute Pain Reduction in Children[NCT04630834] | Phase 4 | 100 participants (Anticipated) | Interventional | 2021-03-30 | Recruiting | ||
| Prospective Randomized Double Blind Study of Intraoperative Dexmedetomidine and Postoperative Pain Control in Patients Undergoing Multi-level Thoraco-lumbar Spine Surgery[NCT01850017] | Phase 4 | 142 participants (Actual) | Interventional | 2012-08-31 | Completed | ||
| Intra-Venous Acetaminophen and Muscle Relaxants After Total Knee Arthroplasty (TKA). Prospective, Randomized, Open-label Trial to Determine if Switching From Oral to Intravenous Acetaminophen and Orphenadrine for 48 Hours After TKA Improves Outcomes.[NCT02449369] | Phase 4 | 180 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Double Blinded Study Ondansetron's Opposite Effect on Postoperative Analgesia of Acetaminophen[NCT02296333] | Phase 4 | 80 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| Analgesic Efficacy of Preoperative Oral Administration of Dexketoprofen Trometamol in Third Molar Surgery, Compared to Postoperative Administration[NCT02380001] | Phase 4 | 60 participants (Actual) | Interventional | 2015-01-31 | Completed | ||
| A Full-Factorial, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Single-Dose Efficacy and Safety Study of an Acetaminophen/Naproxen Sodium Fixed Combination, Acetaminophen, and Naproxen Sodium in Postoperative Dental Pain[NCT05761574] | Phase 3 | 440 participants (Anticipated) | Interventional | 2023-05-22 | Recruiting | ||
| Multimodal Analgesia Versus Routine Care Pain Management for Minimally Invasive Spine Surgery: A Prospective Randomized Study[NCT01861743] | 42 participants (Actual) | Interventional | 2013-04-30 | Terminated (stopped due to data was not collected accurately) | |||
| Effectiveness of Transversus Abdominis Plane Block Versus Quadratus Lumborum Technique in Patients After Cesarean Section[NCT02804126] | Phase 4 | 232 participants (Actual) | Interventional | 2017-06-01 | Completed | ||
| Randomised Controlled Trial Comparing the Effect of Intravenous Dexamethasone vs. Placebo on the Duration of Analgesia of Spinal Anaesthesia for Caesarean Sections at the Victoria Jubilee Hospital in Jamaica[NCT04624360] | Phase 4 | 60 participants (Anticipated) | Interventional | 2020-06-27 | Recruiting | ||
| Low Dose IV Dexamethasone in Prolonging Caudal Anesthesia in Children Undergoing Genitourinary Surgery[NCT02436265] | Phase 4 | 8 participants (Actual) | Interventional | 2015-02-28 | Terminated (stopped due to Lack of enrollment/lack of potential subjects fitting criteria) | ||
| [NCT01041378] | 80 participants (Actual) | Interventional | 2010-01-31 | Completed | |||
| Comparison of Analgesic Efficacy of Dexamethasone as an Adjuvant in Supraclavicular Block With Intravenous Dexamethasone After Supraclavicular Block in Patients Undergoing Forearm Surgeries[NCT04345588] | Phase 2 | 60 participants (Anticipated) | Interventional | 2021-01-01 | Not yet recruiting | ||
| Dexmedetomidine Versus Fentanyl Added to Levobupivacaine for Transversus Abdominis Plane (TAP) Block in Elderly Patients Undergoing Lower Abdominal Surgery[NCT03778671] | Phase 1/Phase 2 | 90 participants (Actual) | Interventional | 2019-01-01 | Completed | ||
| Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial[NCT01904266] | 60 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study[NCT04875559] | 236 participants (Actual) | Observational [Patient Registry] | 2021-04-19 | Completed | |||
| Oral Versus Intravenous Acetaminophen for Postoperative Pain Management After Oocyte Retrieval Procedure. A Double Blinded, Placebo Controlled, Randomized Clinical Trial[NCT04662567] | 42 participants (Actual) | Interventional | 2021-03-12 | Terminated (stopped due to It was determined that the study should not continue as the study drug, Acetaminophen, could only be mixed in a solvent that would not allow the patients to be NPO prior to procedure.) | |||
| Advancing the Multimodal Pathway: Investigating the Use of Sleep and Zolpidem in the Recovery After Shoulder Arthroplasty[NCT03269760] | Phase 1 | 122 participants (Actual) | Interventional | 2017-09-01 | Completed | ||
| Intrathecal Opioid Versus Ultrasound Guided Fascia Iliaca Plane Block for Analgesia After Primary Hip Arthroplasty[NCT01217294] | 108 participants (Actual) | Interventional | 2011-05-31 | Completed | |||
| Lumbar Erector Spinae Plane Block: Cadaveric Study[NCT04166188] | 7 participants (Actual) | Interventional | 2019-06-01 | Completed | |||
| Phase 3 Randomized, Double-Blind Placebo-Controlled, Multicenter, Parallel-Group, Repeated-Dose Study of the Analgesic Efficacy & Safety of IV Acetaminophen Versus Placebo for the Treatment of Postop Pain[NCT00564486] | Phase 3 | 244 participants (Actual) | Interventional | 2007-11-30 | Completed | ||
| Oral Acetaminophen Use for Pain Reduction in Electrophysiology Procedures[NCT03702023] | Phase 4 | 200 participants (Anticipated) | Interventional | 2019-02-08 | Enrolling by invitation | ||
| A Randomized, Double-Blind, Placebo-Controlled, Single Center Study of IV Acetaminophen for the Treatment of Post-Operative Pain After Laparoscopic Roux-en-Y Gastric Bypass Surgery (LRYGBP)[NCT01460667] | 85 participants (Anticipated) | Interventional | 2011-10-31 | Recruiting | |||
| The Scalp Block for Postoperative Pain Control in Craniosynostosis Surgery: a Case Control Study[NCT04133467] | 26 participants (Actual) | Observational | 2016-01-01 | Completed | |||
| Comparison of Pre-emptive Ibuprofen, Acetaminophen, and Placebo Administration in Reducing Local Anesthesia Injection Pain and Post-operative Pain in Primary Tooth Extraction. A Clinical Study[NCT03786029] | Phase 2/Phase 3 | 66 participants (Actual) | Interventional | 2019-04-01 | Completed | ||
| Perioperative Systemic Acetaminophen to Improve Postoperative Quality of Recovery After Ambulatory Breast Surgery[NCT01852955] | 70 participants (Actual) | Interventional | 2013-11-30 | Completed | |||
| Hypoalgesic Effect of Median Nerve Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02596815] | 51 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Hypoalgesic Effect of Neural Mobilization in Cervicobrachial Pain Compared to a Controlled Group[NCT02595294] | 52 participants (Actual) | Interventional | 2015-07-31 | Completed | |||
| Hypoalgesic Effect of Median Nerve Neural Mobilization Versus Ibuprofen Pharmacologic Treatment in Patients With Cervicobrachial Pain[NCT02593721] | Phase 2/Phase 3 | 50 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| Improved Recovery Using Multimodal Peri-operative Analgesia in Minimally Invasive Myomectomy.A Randomized Study.[NCT00978601] | 95 participants (Actual) | Interventional | 2007-01-31 | Completed | |||
| Comparison of the Efficacy of Prophylactic Intraligamentary Injection of Piroxicam Versus Mepecaine for Management of Post-endodontic Pain in Posterior Teeth[NCT03006107] | 26 participants (Anticipated) | Interventional | 2016-12-31 | Not yet recruiting | |||
| Survey of Postoperative Pain and Pain Management in Norwegian Hospitals[NCT01413724] | 300 participants (Actual) | Observational | 2010-06-30 | Completed | |||
| Caudal Epidural Block and Ultrasound-guided Dorsal Penile Nerve Block With the In-plane Technique for Pediatric Distal Hypospadias Surgery: A Prospective Observational Study[NCT04215874] | 26 participants (Actual) | Observational | 2019-04-14 | Completed | |||
| Effect on Initial Endodontic Treatment on Postoperative Pain in Symptomatic Teeth With Pulpal Necrosis[NCT01870973] | 108 participants (Actual) | Interventional | 2013-03-31 | Completed | |||
| Ultrasound Guided Erector Spinae Plane Block in Patients Undergoing Video-assisted Thoracoscopic Surgery (VATS) Lobectomy or Wedge Resections - a Pilot Randomized Control Trial[NCT03176667] | 20 participants (Actual) | Interventional | 2018-12-06 | Completed | |||
| Efficacy of Avoiding Chest Drain After Video-assisted Thoracoscopic Surgery Wedge Resection[NCT05358158] | 94 participants (Anticipated) | Interventional | 2022-05-04 | Recruiting | |||
| Ultrasound-guided Serratus Anterior Plane Block for Thoracic Surgery Pain?[NCT03240562] | 89 participants (Actual) | Interventional | 2017-08-03 | Completed | |||
| Why Are Patients Still in Hospital After Video-Assisted Thoracoscopic Surgery Lobectomy?[NCT04294108] | 160 participants (Actual) | Observational | 2020-04-20 | Completed | |||
| Randomized Control Trial of Ultrasound-Guided Erector Spinae Block Versus Shoulder Periarticular Anesthetic Infiltration for Pain Control After Arthroscopic Shoulder Surgery[NCT03691922] | 62 participants (Actual) | Interventional | 2019-07-06 | Completed | |||
| INTACT-HIP: INTravenous Acetaminophen vs. Oral Randomized Controlled Trial in HIP Fracture Patients - a Feasibility Trial[NCT05425355] | Phase 4 | 42 participants (Anticipated) | Interventional | 2022-11-04 | Not yet recruiting | ||
| The Effect of Intravenous Infusion of Tramadol-ondansetron on Recovery After Caesarean Section. A Prospective, Observational and Non-inferiority Study Against Epidural Analgesia.[NCT05879536] | 312 participants (Anticipated) | Observational | 2023-05-23 | Recruiting | |||
| The Pharmacokinetics of Intravenous Acetaminophen and Its Metabolites in Obese Children and Adolescents[NCT03192566] | Phase 3 | 6 participants (Anticipated) | Interventional | 2016-08-31 | Recruiting | ||
| Anaesthesiological Involvement in Postoperative Pain Treatment - A Questionnaire Survey at Danish Hospitals[NCT03496194] | 42 participants (Actual) | Observational | 2018-04-13 | Completed | |||
| Intravenous Lornoxicam is More Effective Than Paracetamol as a Supplemental Analgesic After Lower Abdominal Surgery; A Randomized Controlled Trial[NCT01564680] | Phase 4 | 60 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Immediate Postoperative Pain and Recovery Time After Pulpotomy Performed Under General Anaesthesia in Young Children[NCT03142672] | 90 participants (Actual) | Interventional | 2016-01-28 | Completed | |||
| Post-operative Analgesia in Elective, Soft-tissue Hand Surgery: A Randomized, Double Blind Comparison of Acetaminophen/Ibuprofen Versus Acetaminophen/Hydrocodone[NCT02029235] | Phase 4 | 72 participants (Actual) | Interventional | 2015-02-10 | Terminated (stopped due to Early termination due to slower than anticipated recruitment.) | ||
| Use of IV Acetaminophen Intraoperatively in Obese Patients at Risk for Obstructive Sleep Apnea Undergoing Laparoscopic Cholecystectomy[NCT02056678] | Phase 4 | 0 participants (Actual) | Interventional | 2014-02-28 | Withdrawn (stopped due to Investigator left institution) | ||
| Adductor Canal Block in an Enhanced Recovery Program After Total Knee Arthroplasty[NCT03915522] | 140 participants (Anticipated) | Interventional | 2018-05-14 | Recruiting | |||
| Prospective, Randomized, Double-Blinded, Allocation Concealed Study Comparing the Efficacy of Liposomal Bupivacaine Over Standard Bupivacaine Plus Dexamethasone in Quadriceps Sparing Femoral Nerve Block and Wound Infiltration for Primary Total Knee Arthro[NCT02624856] | Phase 4 | 0 participants (Actual) | Interventional | 2015-11-30 | Withdrawn (stopped due to Lack of funding) | ||
| Femoral Versus Adductor Canal Continuous Peripheral Nerve Blocks for Knee Arthroplasty[NCT01759277] | Phase 4 | 80 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| Prospective, Double-blind, Randomized Study to Evaluate a Single Shot Adductor Canal Nerve Block Versus Femoral Nerve Block Combined With LIA (Local Infiltration Analgesia): Early Postoperative Period Functional Outcomes After Total Knee Replacement[NCT02218814] | 106 participants (Actual) | Interventional | 2014-08-31 | Completed | |||
| Adductor Canal Mid-thigh and Adductor Canal Distal Thigh: Is Cutaneous Sensory Blockade Similar Among Block Techniques?[NCT02788019] | Phase 4 | 52 participants (Actual) | Interventional | 2016-05-26 | Terminated (stopped due to Unable to complete the sample size needed for 80% power due to changes in surgical approach to adductor block usage.) | ||
| The Efficacy of Adductor-Canal-Blockade on Pain and Morphine Consumption After Total Knee Arthroplasty[NCT01261897] | Phase 4 | 40 participants (Anticipated) | Interventional | 2011-01-31 | Completed | ||
| Optimal Volume of Bupivacaine in Adductor Canal Nerve Block in Patients Undergoing Unilateral Cruciate Ligament Reconstruction Surgery[NCT02557386] | Phase 4 | 60 participants (Anticipated) | Interventional | 2016-01-31 | Recruiting | ||
| Ultrasound Guided Single Shot Adductor Canal Block (ACB) Versus Single Shot Femoral Nerve Block (FNB) for Postoperative Analgesia After Arthroscopic Anterior Cruciate Ligament (ACL) Reconstruction in Pediatrics[NCT03053401] | 52 participants (Actual) | Interventional | 2017-02-09 | Completed | |||
| Continuous Adductor Canal Block With Epidural Analgesia for Total Knee Arthroplasty: A Prospective, Randomized, Double-blinded, Placebo-Controlled Trial[NCT02121392] | 165 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| Randomized Prospective Study Comparing Paravertebral Catheters, Single Shot Paravertebral Block, Thoracic Epidural, for Postoperative Analgesia Following Video-assisted Thoracoscopic Surgery[NCT03151434] | Phase 3 | 147 participants (Actual) | Interventional | 2017-02-07 | Completed | ||
| Continuous Paravertebral Block by Intraoperative Direct Access Versus Systemic Analgesia for Postthoracotomy Pain Relief[NCT04482192] | Phase 3 | 63 participants (Actual) | Interventional | 2015-06-15 | Completed | ||
| An Evaluation of Hydrocodone/Acetaminophen for Pain Control in First Trimester Surgical Abortion[NCT01330459] | Phase 4 | 121 participants (Actual) | Interventional | 2011-02-28 | Completed | ||
| Auricular Acupuncture as Adjunct for Pain Management During First Trimester Uterine Aspiration.[NCT03391986] | 153 participants (Actual) | Interventional | 2017-09-09 | Completed | |||
| Single and Multiple Dose Trial to Evaluate Pharmacokinetics, -Dynamics and Safety of iv Paracetamol in Preterm and Term Neonates[NCT00969176] | Phase 2/Phase 3 | 60 participants (Anticipated) | Interventional | 2009-09-30 | Completed | ||
| A Single-Center, Randomized, Double-Blind, Placebo-Controlled, Single-Dose, Safety and Efficacy Study of Acetaminophen 1000 mg and Acetaminophen 650 mg in Post Operative Dental Pain[NCT01115673] | Phase 3 | 540 participants (Actual) | Interventional | 2010-06-30 | Completed | ||
| IV vs. Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty: a Randomized, Blinded Trial[NCT03020966] | Phase 4 | 154 participants (Actual) | Interventional | 2017-02-16 | Completed | ||
| A Prospective Clinical Trial Evaluating the Post-Operative Analgesic Effects of Acetaminophen Given Per Os and Intravenous[NCT03295214] | Phase 3 | 124 participants (Anticipated) | Interventional | 2018-03-28 | Recruiting | ||
| Ultrasound-guided Transversus Abdominis Plane Block After Abdominal Hysterectomy: a Prospective Randomized Controlled Trial[NCT01153503] | 75 participants (Actual) | Interventional | 2010-04-30 | Completed | |||
| Bilateral Transversus Abdominis Plane Block With or Without Magnesium for Total Abdominal Hysterectomy With or Without Salpingo-oophorectomy: a Randomized Controlled Trial[NCT02680626] | Phase 4 | 86 participants (Actual) | Interventional | 2016-01-31 | Terminated (stopped due to Pfannenstiel hysterectomies are now rarely performed so cannot recruit eligible patients) | ||
| Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Tramadol Consumption in Shoulder Surgery: Prospective, Randomized, Double-Blind Clinical Trial[NCT05401916] | 2 participants (Actual) | Interventional | 2022-06-10 | Completed | |||
| Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Hysterectomy: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial[NCT04691856] | 66 participants (Actual) | Interventional | 2020-12-24 | Completed | |||
| Efficacy of Intravenous Ibuprofen and Paracetamol on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial[NCT03437707] | 3 participants (Actual) | Interventional | 2018-02-13 | Completed | |||
| Evaluation of Postoperative Edema and Pain Following Third Molar Extraction With Application of Pulsed Electromagnetic Field (PEMF) Therapy[NCT02376946] | 49 participants (Actual) | Interventional | 2014-01-31 | Terminated (stopped due to Sponsor decision) | |||
| Comparison of Periosteal and Subcutaneous Infusions of Articaine and Bupivacaine in Treatment of Acute Pain After Sternotomy[NCT01536717] | Phase 4 | 36 participants (Actual) | Interventional | 2012-03-31 | Suspended | ||
| Genetic Basis For Variation In NSAID Analgesia In A Clinical Model Of Acute Pain[NCT00115752] | Phase 2 | 96 participants | Interventional | 2005-06-20 | Completed | ||
| A Phase 3, Multicenter, Randomized, Double-Masked Clinical Trial to Assess the Efficacy and Safety of Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% Compared to Placebo in the Treatment of Inflammation and Pain Associated With Cataract Surgery[NCT04249076] | Phase 3 | 215 participants (Actual) | Interventional | 2020-06-04 | Completed | ||
| A Phase 3, Multicenter, Randomized, Double-Masked Clinical Trial to Assess the Efficacy and Safety of Clobetasol Propionate Ophthalmic Nanoemulsion 0.05% Compared to Placebo in the Treatment of Inflammation and Pain Associated With Cataract Surgery[NCT04246801] | Phase 3 | 250 participants (Actual) | Interventional | 2020-06-10 | Completed | ||
| Assessment of Hemodynamic Response and Pos-operatory Pain in Surgery of Circumcision in Children[NCT00943475] | Phase 4 | 40 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| A Randomized Controlled Trial: Pain Management After Cesarean Section: Oxycodon vs. Intravenous Piritramide[NCT01115101] | Phase 4 | 239 participants (Actual) | Interventional | 2009-07-31 | Completed | ||
| The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Cesarean Delivery[NCT02257346] | 0 participants (Actual) | Interventional | 2014-11-01 | Withdrawn (stopped due to PI terminated study with no subjects enrolled.) | |||
| The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Outpatient Gynecologic Laparoscopy[NCT01250002] | 70 participants (Actual) | Interventional | 2010-11-30 | Completed | |||
| Erector Spinae Plane Block (ESPB): A New Technique for Perioperative Pain Control in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.[NCT03691935] | Phase 4 | 40 participants (Anticipated) | Interventional | 2018-09-28 | Enrolling by invitation | ||
| [NCT01872871] | 80 participants (Anticipated) | Interventional | 2013-01-31 | Recruiting | |||
| Dexmedetomidine as a Sole Premedication for BMT Placement in Children Undergoing Bilateral Myringotomy Tube Placement Surgery[NCT05903326] | 276 participants (Actual) | Observational | 2022-02-11 | Completed | |||
| Prospective, Randomized, Allocation-Concealed, Blinded Study Designed to Compare Ketorolac Sublingual and Fentanyl Intranasal in Pain Control for Bilateral Myringotomy and Tubes (BMT) Placement in Children[NCT02653742] | Phase 4 | 150 participants (Anticipated) | Interventional | 2015-05-31 | Recruiting | ||
| Assessment of the Operative Course in Connection With Removal of Lower Third Molars With Particular Consideration to the Occurence of Pain and Swelling[NCT00805298] | 154 participants (Actual) | Interventional | 2008-08-31 | Completed | |||
| Evaluation of the Effectiveness of the Use of the Therapeutic Bandage Method in Third Molar Surgery. Splint-mouth Randomized Blind Controlled Clinical Trial[NCT03393533] | 7 participants (Actual) | Interventional | 2017-10-20 | Completed | |||
| Topical Hydrocortisone for Pain and Edema Control After Third Molar Surgery: a Clinical, Crossover, Randomized, Double-blind, Controlled Study[NCT03179813] | Phase 4 | 40 participants (Anticipated) | Interventional | 2017-05-01 | Completed | ||
| A Pilot Study of Bupivacaine Infusion in Abdominal Surgery[NCT00280553] | Phase 2 | 60 participants (Anticipated) | Interventional | 2005-04-30 | Recruiting | ||
| Opioid Requirements Post Discharge of Patients Having Total Knee Arthroplasty (TKA)[NCT03106129] | 200 participants (Anticipated) | Observational | 2017-02-09 | Active, not recruiting | |||
| A Comparison of the Efficacy and Safety of ULTRACET® (Tramadol HCl/Acetaminophen) Versus ULTRAM® (Tramadol HCl) Versus Placebo in Subjects With Pain Following Oral Surgery[NCT00236483] | Phase 4 | 456 participants (Actual) | Interventional | 2002-11-30 | Completed | ||
| Efficacy of Two Dental Local Anesthetics on the Oral Health-Related Quality of Life After Endodontic Treatment in the Symptomatic Mandibular Molars: A Double Blind Randomized Controlled Trial[NCT04787731] | Phase 4 | 100 participants (Anticipated) | Interventional | 2019-07-29 | Suspended (stopped due to COVID-19 and Personnel changes) | ||
| Post-operative Pain Following Treatment Using the Gentlewave System[NCT03635515] | 87 participants (Actual) | Interventional | 2018-09-01 | Completed | |||
| Predicting Perioperative Opioid Adverse Effects and Personalizing Analgesia in Children: A Multicenter Pharmacogenetic Study[NCT01495611] | 1,000 participants (Actual) | Observational | 2010-11-30 | Completed | |||
| Effect of Intravenous Paracetamol in Combination With Caudal Ropivacaine on Quality of Postoperative Recovery in Paediatric Patients Undergoing Hypospadias Repair[NCT03781505] | Phase 4 | 64 participants (Anticipated) | Interventional | 2019-01-31 | Recruiting | ||
| Post-tonsillectomy Pain Control in Adults: a Randomized Prospective Study[NCT02358850] | Phase 4 | 27 participants (Actual) | Interventional | 2016-01-31 | Terminated (stopped due to low enrollment) | ||
| Efficacy of the Combination Mepivacaine-Tramadol on the Success of Inferior Alveolar Nerve Block in Patients With Symptomatic Irreversible Pulpitis: a Randomized Clinical Trial.[NCT02110966] | Phase 4 | 56 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| Serratus Anterior Plane Block in Pediatric Patients Undergoing Thoracic Surgeries: A Randomized Controlled Trial[NCT04444635] | 70 participants (Actual) | Interventional | 2020-06-14 | Completed | |||
| Gabapentin as a Pre-emptive Analgesic in Oral and Maxillofacial Surgical Procedures[NCT02957097] | Phase 4 | 0 participants (Actual) | Interventional | 2019-09-30 | Withdrawn (stopped due to Original PI left institution and the PI who took over was not able to initiate the study so it was never started.) | ||
| Effects of Hyperbaric Gaseous Cryotherapy on Knee Flexion Range of Motion in the First Two Days After Total Knee Arthroplasty: A Feasibility Randomized Controlled Trial[NCT02516280] | 65 participants (Actual) | Interventional | 2012-01-31 | Completed | |||
| The Management of Chronic Pain With Acetaminophen Four Times a Day[NCT02086747] | Phase 4 | 140 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| Intravenous Acetaminophen as Adjuvant Therapy for Pain Control in Geriatric Hip Fracture Patients[NCT01520298] | Phase 3 | 0 participants (Actual) | Interventional | 2011-12-31 | Withdrawn (stopped due to Difficulty in recruiting subjects for the trial.) | ||
| A Comparison of Postoperative Tramadol Versus Acetaminophen With Codeine in Children Undergoing Tonsillectomy[NCT01267136] | Phase 4 | 84 participants (Actual) | Interventional | 2011-01-31 | Completed | ||
| Patient Comfort Using Green (532 nm) Versus Yellow (577 nm) Laser Indirect Ophthalmoscopy Panretinal Photocoagulation for Proliferative Diabetic Retinopathy[NCT02995629] | 40 participants (Actual) | Interventional | 2016-03-31 | Completed | |||
| An Observational Prospective Study of Comparing Pain Responses With Pattern Laser Platform and Conventional Laser System During the Panretinal Photocoagulation in Proliferative Diabetic Retinopathy[NCT02645383] | 30 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| A Double Blind Randomized Control Trial on the Efficacy of Periarticular Levo Bupivicaine Injection Following Primary Hip Arthroplasty[NCT01106001] | Phase 4 | 91 participants (Actual) | Interventional | 2008-09-30 | Completed | ||
| The Role of Intra-Operative Intracapsular Blocks in Post-Operative Pain Management Following Total Knee Arthroplasty: A Double-Blinded Randomized Controlled Trial[NCT00620828] | Phase 4 | 67 participants (Actual) | Interventional | 2007-05-31 | Completed | ||
| Ultrasound-Guided Submandibular Parapharyngeal Glossopharyngeal Nerve Block for Post -Tonsillectomy Pain Relief in Adults. A Prospective Randomized Study[NCT05435833] | 50 participants (Actual) | Interventional | 2022-11-05 | Completed | |||
| Ambulant Laparoscopic Nephrectomy[NCT01600157] | 62 participants (Actual) | Interventional | 2013-04-30 | Completed | |||
| Effect of Celecoxib on Postoperative Narcotic Use and Disease Severity in Patients With Aspirin-exacerbated Respiratory Disease and Chronic Rhinosinusitis: a Randomised Controlled Trial[NCT04147013] | Phase 4 | 44 participants (Anticipated) | Interventional | 2020-02-18 | Recruiting | ||
| Intranasal Dexmedetomidine Decreases Emergence Delirium in Pediatric Patients After Sevoflurane Based General Anesthesia[NCT00778063] | 40 participants (Actual) | Interventional | 2008-09-30 | Terminated (stopped due to Difficulty enrolling patients) | |||
| Intravenous Lidocaine Infusion in the Management of Post-operative Pain in Colorectal Patients[NCT01836614] | Phase 1/Phase 2 | 0 participants (Actual) | Interventional | 2015-01-31 | Withdrawn (stopped due to Study was closed due to recommendations of performing a PK study first.) | ||
| Personalizing Perioperative Morphine Analgesia for Adolescents Undergoing Major Spine Surgeries[NCT01839461] | 137 participants (Actual) | Observational | 2009-07-31 | Completed | |||
| Longitudinal Virtual Reality Use in Pediatric Surgical Procedures[NCT03832478] | 0 participants (Actual) | Interventional | 2019-01-01 | Withdrawn (stopped due to Technical difficulty with sending device home with patients) | |||
| Does Anxiety in Children on the Day of Surgery Impact Compliance in the Ophthalmology Clinic?[NCT02704442] | 82 participants (Anticipated) | Observational | 2016-02-29 | Recruiting | |||
| Developing and Testing the Effectiveness of Intelligent Customer-driven Solution for Pediatric Surgery Care on the Improvement of Outcomes of Parents and Their Children Undergoing Circumcision[NCT04174404] | 160 participants (Anticipated) | Interventional | 2019-11-01 | Recruiting | |||
| Use of Handheld Audiovisual Devices to Treat Pediatric Preoperative Anxiety: A Randomized Control Trial.[NCT02286674] | 200 participants (Actual) | Interventional | 2014-11-30 | Completed | |||
| A Randomized Controlled Trial to Compare Pain Medications in Children Undergoing Strabismus Surgery[NCT02789969] | 128 participants (Anticipated) | Interventional | 2016-04-30 | Recruiting | |||
| The Effect of Pre Surgery Dog Visits on Post Surgery Consumption of Pain Medication[NCT00452738] | 0 participants (Actual) | Interventional | 2007-04-30 | Withdrawn (stopped due to PI left university. Did not start study) | |||
| Genetic, Epigenetic, Psychosocial, and Biological Determinants of Post-surgical Pain After Pectus or Spine Surgery[NCT04031716] | 600 participants (Anticipated) | Interventional | 2018-07-06 | Enrolling by invitation | |||
| Adaptive Care in the Perioperative Setting: An Observational Study[NCT03353129] | 60 participants (Actual) | Observational | 2017-08-15 | Completed | |||
| A Pilot Study to Evaluate the Efficacy of Virtual Reality on Pre-Operative Anxiety and Induction of Anesthesia in a Children's Hospital[NCT03239743] | 80 participants (Anticipated) | Interventional | 2017-07-20 | Recruiting | |||
| Intelligent Customer-driven Solution for Children and Their Parents Undergoing Children´s Day Surgery[NCT04277299] | 40 participants (Actual) | Interventional | 2020-08-12 | Completed | |||
| Efficacy of an Educational Pop-Up Book in Preparing Children for Anesthesia: A Randomized Controlled Trial[NCT04796077] | 148 participants (Actual) | Interventional | 2020-08-26 | Completed | |||
| The Effects of Operating Room Virtual Tour on Preoperative Anxiety, Emergence Delirium and Postoperative Behavioral Changes of Pediatric Patients: Prospective, Randomized, and Controlled Trial[NCT03172182] | 86 participants (Actual) | Interventional | 2017-08-01 | Completed | |||
| Non-Interventional Pharmacogenetic Study of Patient / Proxy Controlled Analgesia in Children Undergoing Surgery[NCT01731873] | 182 participants (Actual) | Observational | 2012-01-17 | Completed | |||
| Analgesia Efficacy of Pre-operative and Post-operative PEC I/II Block for Bilateral Mastectomy With Reconstruction[NCT03653988] | 35 participants (Actual) | Interventional | 2019-03-12 | Completed | |||
| Comparison Between Serratus Anterior Plane Block, and Transversus Thoracic Plane Block Combined With Serratus Anterior Plane Block, for the Management of Post-mastecomy Pain.[NCT04375111] | 54 participants (Actual) | Interventional | 2021-06-15 | Completed | |||
| Dexmedetomidine and IV Acetaminophen for the Prevention of Postoperative Delirium Following Cardiac Surgery in Adult Patients 60 Years of Age and Older[NCT02546765] | Phase 4 | 140 participants (Actual) | Interventional | 2015-10-31 | Completed | ||
| Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Rofecoxib 50 mg and Hydrocodone 7.5 mg With Acetaminophen 750 mg in Patients With Postoperative Arthroscopic Pain[NCT00390260] | Phase 3 | 420 participants | Interventional | 2002-02-28 | Completed | ||
| The Effect of Ibuprofen, Paracetamol Versus Placebo on Pain During Local Anesthetic Injection and Following Dental Extraction in Primary Molars: A Randomized Clinical Trial[NCT03184649] | Phase 1/Phase 2 | 52 participants (Anticipated) | Interventional | 2017-05-01 | Enrolling by invitation | ||
| Preoperatively Administered Single Dose Diclofenac Reduces the Intensity of Acute Postcraniotomy Headache and Decreases Postoperative Analgesic Requirements- a Randomized, Controlled Trial[NCT01907984] | Phase 4 | 200 participants (Actual) | Interventional | 2012-12-31 | Completed | ||
| A Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled Study to Evaluate the Efficacy of Rofecoxib and a Dosing Regimen of Oxycodone With Acetaminophen Over 24 Hours in Patients With Postoperative Dental Pain[NCT00092326] | Phase 3 | 269 participants (Actual) | Interventional | 2002-06-30 | Completed | ||
| Low Dose Spinal Morphine for Patients With Obstructive Sleep Apnea (OSA) Undergoing Total Hip Arthroplasty (THA)[NCT01790971] | 40 participants (Anticipated) | Interventional | 2020-01-31 | Suspended (stopped due to competing studies) | |||
| Quality of Recovery Following Administration of Transverse Abdominus Plane (TAP) Catheter as Compared to Intrathecal Morphine After Cesarean Delivery Under Spinal Anesthesia: a Prospective, Randomized Trial[NCT01593280] | 80 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| Intraoperative Wound Instillation of Levobupivacaine is Effective in Postoperative Pain Management for Hernia Repair in Children: a Randomized Controlled Clinical Trial[NCT04869046] | Phase 4 | 100 participants (Actual) | Interventional | 2013-03-31 | Completed | ||
| Use of Caudal Anesthesia Supplemented With Morphine in Children Undergoing Renal Surgery - Prospective Study[NCT01869036] | Phase 4 | 40 participants (Actual) | Interventional | 2012-07-31 | Completed | ||
| The Use of Very Low Dose Caudal Morphine for Postoperative Pain Management in Out Patients[NCT00938821] | 33 participants (Actual) | Observational | 2010-01-31 | Completed | |||
| Pharmacokinetics of Levobupivacaine and Epinephrine for Transversus Abdominis Plane (TAP) Block for Cesarean Section Postoperative Analgesia[NCT02852720] | Phase 4 | 12 participants (Actual) | Interventional | 2016-12-15 | Completed | ||
| Transversus Abdominis Plane (TAP) Block for Cesarean Section[NCT01015807] | 90 participants (Actual) | Interventional | 2009-11-30 | Completed | |||
| Efficacy of the Ultrasound-guidedTransversus Abdominis Plane (TAP) Block on Postoperative Pain Control in Open Aortic Abdominal Aneurysm Repair Surgery[NCT02292667] | Phase 3 | 60 participants (Anticipated) | Interventional | 2015-01-31 | Recruiting | ||
| Analgesic Efficacy of Ultrasound Guided Transversus Abdominis Plane Block After Cesarean Delivery in Patients With a BMI > 30[NCT01217580] | 0 participants (Actual) | Interventional | 2010-10-31 | Withdrawn (stopped due to The study was not feasible to perform at one institution with the amount of subjects that were needed to complete it.) | |||
| Randomized, Prospective, Double Blind Study Comparing Single Shot Versus Continuous Transverses Abdominis Plane (TAP) Block for Postoperative Analgesia After Laparoscopic Live Donor Nephrectomy[NCT02475031] | Phase 4 | 70 participants (Actual) | Interventional | 2012-07-31 | Completed | ||
| Analgesic Efficacy of Transversus Abdominis Plane (TAP) Block After Lumbar Spine Surgery Through Anterior Approach (Anterior Lumbar or Direct Lateral Interbody Fusion): a Prospective, Randomized, Double-blind Placebo-controlled Study[NCT02778178] | Phase 4 | 40 participants (Actual) | Interventional | 2016-05-02 | Completed | ||
| Transversus Abdominis Plane (TAP) Block for Gynaecological Laparotomies - a Comparison of Ultrasound-guided Block and Blind Technique[NCT00972920] | 120 participants (Anticipated) | Interventional | 2009-08-31 | Completed | |||
| The Postoperative Analgesic Efficacy of Varied Concentrations of Ropivacaine Used for the Transverse Abdominis Plane (TAP) Block After Cesarean Delivery[NCT01170702] | Phase 4 | 120 participants (Actual) | Interventional | 2010-01-31 | Completed | ||
| Effect of Transversus Abdominis Plane (TAP) Block and the Perioperative Stress Response: Randomized Control Trial in Patient Undergoing Total Abdominal Hysterectomy in a Tertiary Care Hospital of Pakistan[NCT03443271] | Phase 4 | 50 participants (Actual) | Interventional | 2016-06-17 | Completed | ||
| Decreased Neuraxial Morphine and Adjunctive Peripheral Nerve Blockade to Reduce Severity of Side Effects and Opioid Use After Cesarean Delivery[NCT04279054] | Early Phase 1 | 87 participants (Actual) | Interventional | 2020-09-09 | Active, not recruiting | ||
| Effect of a Transversus Abdominis Plane Block on Operative Wound Healing, Stress, and Immune Response After a Cesarean Delivery[NCT05840406] | 120 participants (Anticipated) | Interventional | 2024-04-01 | Not yet recruiting | |||
| Transversus Abdominis Bilateral Plane Block in Total Laparoscopic Hysterectomy : A Randomized Controlled Trial[NCT01596660] | 200 participants (Anticipated) | Interventional | 2011-08-31 | Recruiting | |||
| Comparison of Oral Gabapentin and Pregabalin in Postoperative Pain Control After Photorefractive Keratectomy: a Prospective, Randomized Study.[NCT00954187] | 8 participants (Actual) | Interventional | 2009-11-30 | Terminated (stopped due to PI left institution) | |||
| Pre-Emptive Analgesic Effects of a Selective COX-2 Inhibitor (Rofecoxib) in the Oral Surgery Model[NCT00026819] | Phase 2 | 150 participants | Interventional | 2001-11-30 | Completed | ||
| A New Approach to Ilio-inguinal Nerve Blocks: 3-layer Injection vs Conventional Ultrasound-guided Single-shot Approach[NCT01625780] | 32 participants (Actual) | Interventional | 2012-04-30 | Terminated (stopped due to Not a significant difference in outcomes between groups) | |||
| Effective Analgesia Using the 5 S's During Routine Immunizations at 2 and 4 Months[NCT01368861] | 230 participants (Actual) | Observational | 2010-06-30 | Completed | |||
| Preoperative Controlled-Release Oxycodone or Intraoperative Morphine As Transition Opioid After Intravenous Anesthesia For Video-Assisted Thoracic Surgery: a Randomized, Double-blind, Controlled Trial.[NCT00681174] | Phase 4 | 22 participants (Actual) | Interventional | 2008-07-31 | Terminated (stopped due to Failure to enroll sufficient patients by expected deadline.) | ||
| Ultrasound Guided Caudal Block Versus Quadratus Lumborum Block for Inguinal Hernioraphy in Preschool Children.[NCT03811392] | 60 participants (Actual) | Interventional | 2019-10-01 | Completed | |||
| "Comparison of Analgesic Effects of USG-Guided Caudal Versus Ilioinguinal/Iliohypogastric Nerve Block Techniques for Inguinal Surgeries in Children, a Randomized Controlled Trial."[NCT05558748] | 128 participants (Anticipated) | Interventional | 2022-12-06 | Recruiting | |||
| Efficacy of Ultrasound-Guided Transversus Abdominis Plane Block for Postoperative Pain Control in Laparoscopic Cholecystectomy: Prospective Randomized Controlled Trial in Pediatric Patients[NCT02712151] | Phase 3 | 80 participants (Anticipated) | Interventional | 2024-03-01 | Not yet recruiting | ||
| Short Term Topical Tetracaine is Safe and Highly Efficacious for the Treatment of Pain Caused by Corneal Abrasions: a Double-blind Randomized Clinical Trial[NCT04187417] | 118 participants (Actual) | Interventional | 2015-01-01 | Completed | |||
| Comparing Narcotics With Non-steroidal Anti-inflammatory Drugs (NSAIDS) Post-operatively in Pediatric Patients Undergoing Adenotonsillectomy[NCT02296840] | Phase 4 | 45 participants (Actual) | Interventional | 2014-11-30 | Terminated | ||
| A Prospective, Randomized, Double-Blind, Active-Comparator, Pilot Study to Observe Relative Efficacy of Ultrasound-Guided Erector Spinae Plane Block (ESP) vs. Combination of Ultrasound - Guided Erector Spinae Plane Block With Serratus Anterior Plane Block[NCT04349774] | Phase 4 | 0 participants (Actual) | Interventional | 2022-10-01 | Withdrawn (stopped due to Study was never initiated due to COVID-19) | ||
| The cryoICE™ CryoAnalgesia Study For Pain Management in Post thoRacic Procedures Via intercOSTal Cryoanalgesia (FROST)[NCT02922153] | 84 participants (Actual) | Interventional | 2016-06-13 | Completed | |||
| Comparison of Caudal Bupivacaine Alone With Bupivacaine Plus Two Doses of Dexmedetomidine for Postoperative Analgesia in Pediatric Patients Undergoing Infra-umbilical Surgery: A Randomized Controlled Double Blinded Study[NCT02385435] | Phase 2/Phase 3 | 91 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Randomized Control Trial of Combined Cryotherapy With Compression Versus Cryotherapy Alone After Orthopaedic Surgery[NCT05011084] | 504 participants (Anticipated) | Interventional | 2020-11-02 | Recruiting | |||
| The Effects of Propofol vs. Sevoflurane Administered During Anesthesia Maintenance on Early and Late Recovery After Gynecological Surgery[NCT01755234] | Phase 4 | 90 participants (Actual) | Interventional | 2012-11-30 | Completed | ||
| Spinal Hydromorphone Versus Morphine for Post-Cesarean Delivery Analgesia: A Non-Inferiority Trial[NCT03592992] | Phase 4 | 126 participants (Actual) | Interventional | 2020-11-11 | Completed | ||
| Intrathecal Opioids for Pain Control After Cesarean Delivery: Determining the Optimal Dose[NCT02009722] | Phase 4 | 84 participants (Actual) | Interventional | 2014-01-31 | Completed | ||
| Phase III Clinical Trial Studying Analgesic Efficacy of Morphine Alone or Combined With Paracetamol and/or Ibuprofen for Long-bones Fractures in Children[NCT02477007] | Phase 3 | 304 participants (Actual) | Interventional | 2015-12-03 | Completed | ||
| Analgesic Effect of Ibuprofen 400 mg/Paracetamol 1000 mg, Ibuprofen 400 mg/ Paracetamol 1000 mg/60 mg Codeine, and Paracetamol 1000 mg/Codeine 60 mg: A Single-dose, Randomized, Placebo-controlled and Double-blind Study[NCT00921700] | Phase 4 | 200 participants (Actual) | Interventional | 2009-06-30 | Completed | ||
| Improving Post-Operative Pain and Recovery in Gynecologic Surgery[NCT04175509] | Phase 4 | 40 participants (Actual) | Interventional | 2019-12-23 | Completed | ||
| Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction[NCT03893175] | Phase 1 | 86 participants (Actual) | Interventional | 2019-05-10 | Completed | ||
| Effectiveness of Distal Peripheral Nerve Blocks on Postoperative Pain Management After Ambulatory Thumb Resection Arthroplasty.[NCT01597479] | Phase 4 | 52 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| Perioperative IV Steroid Administration Lowers Post-operative Pain Levels and Opioid Use in Pediatric Patients After Posterior Spinal Fusion and Instrumentation for Spine Deformity.[NCT05287035] | Early Phase 1 | 70 participants (Anticipated) | Interventional | 2023-07-01 | Enrolling by invitation | ||
| [NCT01833728] | 16 participants (Actual) | Interventional | 2013-04-30 | Completed | |||
| Effect of Preoperative, Single-dose Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Double-Blind Randomized Controlled Trial.[NCT03033147] | 72 participants (Actual) | Interventional | 2019-10-18 | Completed | |||
| Effect of Amoxicillin/Clavulanic Acid Combination on Postoperative Endodontic Pain in Patients With Symptomatic Apical Periodontitis: A Randomized Controlled Trial[NCT03007342] | 78 participants (Anticipated) | Interventional | 2017-01-31 | Not yet recruiting | |||
| Fast-track Laparoscopic Surgery. The Effect of Anesthetic Technique[NCT01275911] | 40 participants (Actual) | Interventional | 2009-01-31 | Completed | |||
| Intra-operative Magnesium Sulphate for Post-operative Pain in Patients Undergoing Total Abdominal Hysterectomy Under General Anesthesia[NCT06026527] | Phase 3 | 42 participants (Anticipated) | Interventional | 2023-10-31 | Not yet recruiting | ||
| The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in[NCT02852382] | Phase 2 | 45 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| Evaluation of the Efficacy of the Photobiomodulation on the Pelvi-perineal Pain in Patients in Immediate Post-partum Situation[NCT04896034] | 677 participants (Anticipated) | Interventional | 2021-05-06 | Recruiting | |||
| Evaluation of the Analgesic Effects of Locally Applied Flurbiprofen and Bupivacaine in the Oral Surgery Model[NCT00001724] | Phase 2 | 100 participants | Interventional | 1997-11-30 | Completed | ||
| Ropivacaine Through Continuous Infusion Versus Epidural Morphine for Postoperative Analgesia After Emergency Cesarean Section[NCT02410317] | Phase 3 | 101 participants (Actual) | Interventional | 2015-02-28 | Completed | ||
| Randomized, Controlled, Double Blind, to Evaluate the Postpartum Analgesia With Epidural Morphine: Analgesic Effect of Two Different Doses Compared to Placebo[NCT04887649] | Phase 3 | 114 participants (Actual) | Interventional | 2009-03-31 | Completed | ||
| Transcutaneous Electrical Nerve Stimulation and Maternal Opioid Use After Cesarean Delivery[NCT03843788] | 20 participants (Anticipated) | Interventional | 2018-11-09 | Active, not recruiting | |||
| Ibuprofen vs. Codeine. Is One Better for Post-operative Pain Relief Following Reduction of Paediatric Forearm Fractures?[NCT01605240] | 50 participants (Anticipated) | Interventional | 2012-07-31 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Number of patients who score greater than a 4 on the 0-8 point ICDSC scale to assess delirium scores. 8 separate levels of signs for delirium assessed (1. altered level of consciousness, 2. inattention, 3. disorientation, 4. hallucination, delusion, or psychosis, 5. psychomotor agitation or retardation, 6. inappropriate speech or mood, 7. sleep-wake cycle disturbance, 8. symptom fluctuation), with 0 points awarded when patient does not exhibit above signs of delirium and 1 point awarded per confirmed sign of delirium. Score then totaled, 0 = normal, 1-3 = subsyndromal delirium, 4-8 = delirium. (NCT03198871)
Timeframe: The delirium scores will first be measured every 12 hours for 72 hours after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 0 |
| Sodium Chloride 0.9%, Intravenous | 0 |
If the patient is readmitted to the hospital after being fully discharged, the event will be recorded. (NCT03198871)
Timeframe: From the time of consent until 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 9 |
| Sodium Chloride 0.9%, Intravenous | 10 |
Number of patients with unsatisfactory pain relief defined as average numeric rating scale (NRS) more than 5 will be compared between the two groups. This may include patients using IVPCA for pain relief during the first 48 hours postoperative. (NCT03198871)
Timeframe: PACU admission every thirty minutes until discharge to the floor and thereafter every four hours for first 24-hour, then every six hours until 48 hours and then every twelve hours until 72 hours postoperatively.
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 33 |
| Sodium Chloride 0.9%, Intravenous | 42 |
The time it takes for the patient to successfully ambulate post-surgery will be measured. (NCT03198871)
Timeframe: From date of PACU admission until the date of first documented ambulation, assessed up to 72 hours postoperatively
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 18.82 |
| Sodium Chloride 0.9%, Intravenous | 17.38 |
The time it takes for the first bowel movement postoperatively will be measured. (NCT03198871)
Timeframe: From time patient left operating room until the time of first documented bowel movement, assessed up to hospital discharge
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 46.30 |
| Sodium Chloride 0.9%, Intravenous | 64.66 |
The time it takes for the patient to be fully discharged from the hospital post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of hospital discharge or 30 days postoperatively, whichever comes first
| Intervention | days (Median) |
|---|---|
| Acetaminophen Injectable Product | 4.08 |
| Sodium Chloride 0.9%, Intravenous | 4.94 |
The time it takes for the patient to ingest orally post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of first documented oral intake, assessed up to 72 hours postoperatively
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 12.15 |
| Sodium Chloride 0.9%, Intravenous | 9.40 |
The time from PACU admission to PACU discharge to the floor will be measured. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge, assessed up to 24 hours postoperatively
| Intervention | minutes (Median) |
|---|---|
| Acetaminophen Injectable Product | 129.00 |
| Sodium Chloride 0.9%, Intravenous | 152.50 |
Overall patient satisfaction as well as satisfaction relating to pain management and cost analyses will be measured. These will be measured with a numerical rating scale (NRS) with 0- being worst satisfaction and 10 - best satisfaction. (NCT03198871)
Timeframe: These measurements will be taken at time of discharge up to 30 days, whichever comes first
| Intervention | score on a scale (Median) | |
|---|---|---|
| Patient satisfaction score, overall | Patient Satisfaction score, pain management | |
| Acetaminophen Injectable Product | 10 | 10 |
| Sodium Chloride 0.9%, Intravenous | 10 | 10 |
Frequency of emesis and rescue antiemetic requirement will be documented (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Emesis incidence 0-72 hours | Antiemetic use | |
| Acetaminophen Injectable Product | 12 | 31 |
| Sodium Chloride 0.9%, Intravenous | 14 | 45 |
Nausea will be evaluated by nausea score from 0 to 10, with 0 equaling no nausea and 10 equaling the worst nausea imaginable. (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Nausea score POD 1 (am visit) | Nausea score POD 1 (pm visit) | Nausea score POD 2 (am visit) | Nausea score POD 2 (pm visit) | Nausea score POD 3 (am visit) | Nausea score POD 3 (pm visit) | |
| Acetaminophen Injectable Product | 1.13 | 0.49 | 0.71 | 0.55 | 0.32 | 0.56 |
| Sodium Chloride 0.9%, Intravenous | 0.60 | 0.92 | 0.75 | 0.69 | 0.66 | 0.78 |
Survey to assess patient's overall health (via a combination of mental and physical health assessment) at 30 days post-discharge. Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12). The scores may be reported as Z-scores (difference compared to the population average, measured in standard deviations). The United States population average PCS-12 and MCS-12 are both 50 points. The United States population standard deviation is 10 points. So each 10 increment of 10 points above or below 50, corresponds to one standard deviation away from the average (NCT03198871)
Timeframe: These measurements will take place at 30-days post hospital discharge
| Intervention | Z-scores (difference compared to the pop (Median) | |
|---|---|---|
| SF 12 Physical score | SF 12 Mental score | |
| Acetaminophen Injectable Product | 38.72 | 54.02 |
| Sodium Chloride 0.9%, Intravenous | 38.07 | 52.08 |
Rescue analgesia will be given according to institutional pain management protocol. Unit of Measure recorded as OME (Oral Morphine Equivalent) consumption in mg. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge and 72-hours postoperatively, whichever comes first
| Intervention | mg (Median) | ||||
|---|---|---|---|---|---|
| 0-24 hours | 24-48 hours | 48-72 hours | 0-48 hours | 0-72 hours | |
| Acetaminophen Injectable Product | 27.4 | 31.3 | 30 | 74 | 105.00 |
| Sodium Chloride 0.9%, Intravenous | 36 | 45 | 37.5 | 88.8 | 127.1 |
"A Pain Intensity Difference (PID) is the difference between the Visual Analogue Scale (VAS) pain intensity score recorded at baseline and a score recorded at any time after the first dose of study medication. Taken together, a patient's PID scores capture the pain relief profile attributable to the assigned study medication. A high PID score indicates a better pain relief experienced.~The extent of pain relief can then be calculated by the Area Under the Curve the PID scores (also referred to as the Sum of Pain Intensity Differences [SPID]). SPID48 scores were adjusted by the time interval from baseline to the final VAS score used in the SPID, using the following formula:~Time-adjusted SPID48 (mm) = SPID (mm*hr) / Time (hr) In the event that a patient required rescue medication, the SPID was calculated up until the first Pre-Rescue VAS pain assessment (inclusive)." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic IV | 23.4 |
| IV Acetaminophen | 10.4 |
| IV Ibuprofen | 9.5 |
| Placebo IV | -1.3 |
"At the end of 48 hours study period, participants will be asked to How do you rate the study medication? on a 5 point categorical scale:~Poor~Fair~Good~Very Good~Excellent The high score means the participants believed that a better treatment for pain relief received." (NCT02689063)
Timeframe: 48 hrs after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 24 |
| IV Acetaminophen | 5 |
| IV Ibuprofen | 8 |
| Placebo IV | 1 |
"VAS Pain intensity difference (PID) at each scheduled assessment time point after Time 0.~A Pain Intensity Difference (PID) is the difference between the Visual Analogue Scale (VAS) pain intensity score recorded at baseline and a score recorded at any time after the first dose of study medication. Taken together, a patient's PID scores capture the pain relief profile attributable to the assigned study medication. A high PID score indicates a better pain relief experienced." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic IV | 52.50 |
| IV Acetaminophen | 38.95 |
| IV Ibuprofen | 45.04 |
| Placebo IV | 37.24 |
"VAS Pain intensity score at each scheduled assessment time point VAS pain intensity score-marking on a 100 mm VAS scale with anchors for no pain (0 mm) and worst pain imaginable (100 mm). A high VAS score indicates a more intensive pain level experienced." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic IV | 18.43 |
| IV Acetaminophen | 29.28 |
| IV Ibuprofen | 27.21 |
| Placebo IV | 28.22 |
Treatment-emergent Adverse events coded to MedDRA v 20.0 Preferred Term and System Organ Class Code were tabulated as the counts and percentages by treatment group. (NCT02689063)
Timeframe: Day 7
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 52 |
| IV Acetaminophen | 45 |
| IV Ibuprofen | 58 |
| Placebo IV | 39 |
"Peak Pain Relief was assessed on Pain Relief scores (on a 5 point categorical rating-please see outcome measure description No. 7) recorded up until the first dose of rescue (First Pre-Rescue Pain Relief score inclusive).~The percentage of participants who achieve the peak pain relief was summarized." (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 22 |
| IV Acetaminophen | 11 |
| IV Ibuprofen | 4 |
| Placebo IV | 3 |
"Pain relief score was assessed on a 5-point categorical scale at each scheduled time point after Time 0:~0 = No pain relief (the pain is the same, or worse, than the starting pain)~= A little pain relief (the pain is less than half gone)~= some pain relief (the pain is about half gone)~= A lot pain relief (the pain is more than half gone)~= Complete pain relief (the pain is completely gone)~Assessed at scheduled time points:~5, 10, 15, 30, 45 minutes, 1, 1.5, 2, 3, 4, 5, 6 hours after the first dose of the study drug~Immediately before and 2 hours after each subsequent dose (doses 2-8) of the study drug while awake~At the end of 48 hours of double-blind treatment period~Immediately before taking each dose of the rescue medication if additional analgesia is required.~At the time of withdrawal (if applicable)" (NCT02689063)
Timeframe: 48 hours after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 29 |
| IV Acetaminophen | 7 |
| IV Ibuprofen | 16 |
| Placebo IV | 4 |
The percentage of participants who used at lease one dose of rescue medication was summarized in each treatment group (NCT02689063)
Timeframe: 48 hrs after the first dose
| Intervention | Participants (Count of Participants) |
|---|---|
| Maxigesic IV | 56 |
| IV Acetaminophen | 70 |
| IV Ibuprofen | 70 |
| Placebo IV | 48 |
"Time to peak pain relief-Peak Pain Relief was assessed on Pain Relief scores recorded up until the first dose of rescue (First Pre-Rescue Pain Relief score inclusive). Time for participants who experienced peak pain relief was summarized.~Note: For the reader to interpret this outcome measure, a very short Time to Peak Pain Relief indicates the absence of analgesic effect for a treatment because peak pain relief was determined prior to the first dose of rescue medication (or 48 hours if no rescue medication was used)." (NCT02689063)
Timeframe: 48 hrs after the first dose
| Intervention | hours (Mean) |
|---|---|
| Maxigesic IV | 4.00 |
| IV Acetaminophen | 2.46 |
| IV Ibuprofen | 1.47 |
| Placebo IV | 0.91 |
Time to first use of rescue medication (duration of analgesia) (NCT02689063)
Timeframe: 48 hrs
| Intervention | hours (Mean) |
|---|---|
| Maxigesic IV | 12.98 |
| IV Acetaminophen | 5.62 |
| IV Ibuprofen | 3.09 |
| Placebo IV | 2.92 |
"Two-stopwatch method~Start two stopwatches ('Stopwatch A' and 'Stopwatch B') at the same time that the infusion of study drug is initiated. This is Time 0.~The participant is given 'Stopwatch A' and instructed to Stop 'Stopwatch A' when you first feel any pain relief whatsoever. This does not mean you feel completely better, although you might, but when you first feel any relief in the pain you have now. (Perceptible Pain Relief)~When the participant stops the 'Stopwatch A', the participant then was asked Do you consider the pain relief you experienced meaningful?~If the participant answered No, then the participant was given the Stopwatch B and instructed to Stop 'Stopwatch B' when you feel the pain relief is meaningful to you (Meaningful Pain Relief)~If the subject did not experience perceptible pain relief, they would retain 'Stopwatch A' for the entire 6 hour evaluation period." (NCT02689063)
Timeframe: 6 hours
| Intervention | minutes (Median) |
|---|---|
| Maxigesic IV | 9.4 |
| IV Acetaminophen | 23.9 |
| IV Ibuprofen | 13.8 |
| Placebo IV | 0 |
"Time adjusted SPID-6, SPID-12, SPID-24 were derived in a similar manner to the Time-adjusted SPID-48 (i.e. up until the first Pre-Rescue VAS inclusive). Please see the primary outcome measure descriptions.~Each of these variables were derived from VAS (Visual Analogue Scale) scores recorded prior to the first dose of rescue medication in the first 6 (to calculate SPID6), 12 (to calculate SPID12) or 24 hours (to calculate SPID24) of the study.~VAS pain intensity scores were obtained by marking on a 100 mm VAS scale with anchors for no pain (0 mm) and worst pain imaginable (100 mm). The VAS was completed at rest." (NCT02689063)
Timeframe: 6, 12, 24 hours after the first dose
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| SPID 6 | SPID 12 | SPID 24 | |
| IV Acetaminophen | 10.13 | 9.42 | 9.59 |
| IV Ibuprofen | 9.01 | 8.44 | 8.64 |
| Maxigesic IV | 20.10 | 20.63 | 21.99 |
| Placebo IV | -1.49 | -1.66 | -1.54 |
Total use of rescue analgesia over 0 to 24 hours and over 0 to 48 hours (NCT02689063)
Timeframe: 24, 48 hrs after the first dose
| Intervention | mg (Mean) | |
|---|---|---|
| Total Dose in 48 hrs | Total Dose in 24 hrs | |
| IV Acetaminophen | 33.1 | 23.7 |
| IV Ibuprofen | 32.4 | 22.1 |
| Maxigesic IV | 22.9 | 17.2 |
| Placebo IV | 44.7 | 29.6 |
"Total Pain Relief (TOTPAR) is a measure of total Area Under the Curve of Pain Relief scores. In the event that a patient required rescue medication, the TOTPAR endpoints were calculated using Pain Relief Assessments recorded prior to the first dose of rescue (i.e. inclusive of the first pre-rescue Pain Relief score).~Pain relief scores were obtained by marking on a 5-point categorical rating at scheduled time points.~The high score means more pain relief experienced:~0 = No pain relief (the pain is the same, or worse, than the starting pain)~= A little pain relief (the pain is less than half gone)~= some pain relief (the pain is about half gone)~= A lot pain relief (the pain is more than half gone)~= Complete pain relief (the pain is completely gone) Each of these variables were derived from pain relief scores recorded prior to the first dose of rescue medication in the first 6 (0-48), 12 (0-48), 24 (0-48) or 48 (0-48) hours of the study." (NCT02689063)
Timeframe: 6, 12, 24, 48 hours after the first dose
| Intervention | score on a scale*hour (Mean) | |||
|---|---|---|---|---|
| TOTPAR 6 | TOTPAR 12 | TOTPAR 24 | TOTPAR 48 | |
| IV Acetaminophen | 4.59 | 6.74 | 8.66 | 13.28 |
| IV Ibuprofen | 3.34 | 4.46 | 6.51 | 11.95 |
| Maxigesic IV | 6.84 | 11.86 | 22.13 | 43.98 |
| Placebo IV | 1.60 | 1.82 | 2.49 | 4.51 |
The number of oocytes retrieved from the patient's ovaries as part of an in vitro-fertilization treatment. This includes both immature and mature oocytes. (NCT03073980)
Timeframe: 0 days
| Intervention | oocytes (Mean) |
|---|---|
| Group A: IV Acetaminophen/PO Placebo | 12.6 |
| Group B: IV Placebo/PO Acetaminophen | 13.4 |
| Group C: IV Placebo/ PO Placebo | 11.4 |
Visual analog scale of pain, ranging from 0 (no pain) to 10 (worst pain imaginable) in whole numbers. The final score is the post-operative score minus the pre-operative score. (NCT03073980)
Timeframe: Pain was measured pre-operatively and at 10 minutes post-procedure.
| Intervention | score on a scale (Mean) |
|---|---|
| Group 1: IV Acetaminophen/PO Placebo | 1.3 |
| Group 2: IV Placebo/PO Acetaminophen | 1.3 |
| Group 3: IV Placebo/PO Placebo | 1.8 |
One or more episodes of nausea and vomiting in the recovery room and through post-operative day 2 (NCT03073980)
Timeframe: 0-2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Group A: IV Acetaminophen/PO Placebo | 3 |
| Group B: IV Placebo/PO Acetaminophen | 4 |
| Group C: IV Placebo/ PO Placebo | 2 |
Duration of egg retrieval (NCT03073980)
Timeframe: 0-2 hours
| Intervention | minutes (Mean) |
|---|---|
| Group A: IV Acetaminophen/PO Placebo | 13.5 |
| Group B: IV Placebo/PO Acetaminophen | 13.7 |
| Group C: IV Placebo/ PO Placebo | 14.1 |
One or more doses of opiate pain medication given due to pain during the procedure or immediately post-operative in the recovery room. (NCT03073980)
Timeframe: During procedure and immediately post-operative in recovery room within 45 minutes
| Intervention | Participants (Count of Participants) |
|---|---|
| Group A: IV Acetaminophen/PO Placebo | 4 |
| Group B: IV Placebo/PO Acetaminophen | 10 |
| Group C: IV Placebo/ PO Placebo | 8 |
Discharge time was based on the nurse's assessment of patient alertness, ability to tolerate oral liquids and food, and ability to void. (NCT03073980)
Timeframe: 0-6 hours post-procedure
| Intervention | minutes (Mean) |
|---|---|
| Group 1: IV Acetaminophen/PO Placebo | 60.1 |
| Group 2: IV Placebo/PO Acetaminophen | 58.8 |
| Group 3: Placebo / Standard of Care | 57.6 |
"To quantify the use of opioid analgesics in treatment of post-operative dental pain, the amount of rescue medications (opioids) was converted to a standard unit, which was Morphine Milligram Equivalent (MME) using below formula:~MME/Day = Strength per Unit × (Number of units / Days supply) × MME conversion factor" (NCT04307940)
Timeframe: Up to 12 hours postdose
| Intervention | Morphine Milligram Equivalent (MME) (Mean) |
|---|---|
| Naproxen Sodium | 7.8 |
| Hydrocodone / APAP | 9.3 |
| Placebo | 10.5 |
(NCT04307940)
Timeframe: Up to 12 hours postdose
| Intervention | Hours (Least Squares Mean) |
|---|---|
| Naproxen Sodium | 8.87 |
| Hydrocodone / APAP | 6.57 |
| Placebo | 3.31 |
(NCT04307940)
Timeframe: Up to 6 hours postdose
| Intervention | Hours (Least Squares Mean) |
|---|---|
| Naproxen Sodium | 4.60 |
| Hydrocodone / APAP | 4.08 |
| Placebo | 1.49 |
Pain intensity is measured using Numerical Rating Scale (from 0 to 10: 0 = no pain, 10 = worst possible pain). For each post dose time point, pain intensity difference (PID) is derived by subtracting the pain intensity at the post dose time point from the baseline intensity score (baseline score - post-baseline score). A positive difference is indicative of improvement. Sum of Pain Intensity Differences (SPIDs) was calculated by multiplying the PID score at each post-dose time point by the duration (in hours) since the preceding time point and then summing these values over the specific time period. SPID over 12 hours ranges from -120 to 120. A higher value indicates a better pain reduction. (NCT04307940)
Timeframe: Up to 12 hours postdose
| Intervention | Scores on a scale*hours (Least Squares Mean) |
|---|---|
| Naproxen Sodium | 53.20 |
| Hydrocodone / APAP | 38.39 |
| Placebo | 13.57 |
Pain intensity is measured using Numerical Rating Scale (from 0 to 10: 0 = no pain, 10 = worst possible pain). For each post dose time point, pain intensity difference (PID) is derived by subtracting the pain intensity at the post dose time point from the baseline intensity score (baseline score - post-baseline score). A positive difference is indicative of improvement. Sum of Pain Intensity Differences (SPIDs) was calculated by multiplying the PID score at each post-dose time point by the duration (in hours) since the preceding time point and then summing these values over the specific time period. SPID over 6 hours ranges from -60 to 60. A higher value indicates a better pain reduction. (NCT04307940)
Timeframe: Up to 6 hours postdose
| Intervention | Scores on a scale*hours (Least Squares Mean) |
|---|---|
| Naproxen Sodium | 28.41 |
| Hydrocodone / APAP | 24.35 |
| Placebo | 6.23 |
If a subject did not take the rescue medication during the treatment period, (s)he was censored at the time of last assessment. (NCT04307940)
Timeframe: Up to 12 hours postdose
| Intervention | Hours (Median) |
|---|---|
| Naproxen Sodium | NA |
| Hydrocodone / APAP | 10.42 |
| Placebo | 2.57 |
Pain relief is measured using Categorical Pain Relief Rating Scale (0 = No relief, 1 = A little relief, 2 = Some relief, 3 = A lot of relief, 4 = Complete relief). Total Pain Relief is calculated as the area under the curve of pain relief score over time for the given time period by multiplying the pain relief score at each time point by the duration (in hours) since the preceding time point and then summing these values over the specific time period. TOTPAR over 12 hours ranges from 0 to 48, a higher value indicates more pain relief. (NCT04307940)
Timeframe: Up to 12 hours postdose
| Intervention | Scores on a scale*hours (Least Squares Mean) |
|---|---|
| Naproxen Sodium | 28.41 |
| Hydrocodone / APAP | 21.31 |
| Placebo | 10.63 |
Pain relief is measured using Categorical Pain Relief Rating Scale (0 = No relief, 1 = A little relief, 2 = Some relief, 3 = A lot of relief, 4 = Complete relief). Total Pain Relief is calculated as the area under the curve of pain relief score over time for the given time period by multiplying the pain relief score at each time point by the duration (in hours) since the preceding time point and then summing these values over the specific time period. TOTPAR over 6 hours ranges from 0 to 24, a higher value indicates more pain relief. (NCT04307940)
Timeframe: Up to 6 hours postdose
| Intervention | Scores on a scale*hours (Least Squares Mean) |
|---|---|
| Naproxen Sodium | 14.53 |
| Hydrocodone / APAP | 12.69 |
| Placebo | 5.14 |
(NCT04307940)
Timeframe: Up to 12 hours postdose
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Number of participants required rescue pain medication | Number of participants did not require any rescue pain medication | |
| Hydrocodone / APAP | 43 | 40 |
| Naproxen Sodium | 18 | 68 |
| Placebo | 29 | 14 |
(NCT01635101)
Timeframe: within 24 hours
| Intervention | hours (Median) |
|---|---|
| Low Dose Acetaminophen | 4.78 |
| High Dose Acetaminophen | 4.76 |
| Placebo | 3.81 |
Total micrograms per kilogram (µg/kg) of rescue opioid used during the same 24 hours the subject is on study medication (NCT01635101)
Timeframe: in 24 hours
| Intervention | µg/kg (Mean) |
|---|---|
| Low Dose Acetaminophen | 166.9 |
| High Dose Acetaminophen | 179.9 |
| Placebo | 180.2 |
The Face, Leg, Activity, Cry, and Consolability (FLACC) scale is used to assess pain intensity in intermediate aged infants. The scale is scored in a range of 0-10 with 0 representing no pain. A higher score means more pain. (NCT01635101)
Timeframe: within 24 hours
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| at 0 hours | at 6 hours | at 12 hours | at 18 hours | at 24 hours | |
| High Dose Acetaminophen | 1.6 | 2.1 | 0.08 | 0.9 | 0.9 |
| Low Dose Acetaminophen | 0.6 | 0.7 | 1.2 | 1.4 | 1.4 |
| Placebo | 1.2 | 1.4 | 1.8 | 0.5 | 0.3 |
The FLACC scale is used to assess pain intensity in older infants. The scale is scored in a range of 0-10 with 0 representing no pain. A higher score means more pain. (NCT01635101)
Timeframe: within 24 hours
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| at 0 hours | at 6 hours | at 12 hours | at 18 hours | at 24 hours | |
| High Dose Acetaminophen | 1.8 | 1.2 | 1.7 | 0.1 | 0.8 |
| Low Dose Acetaminophen | 2.2 | 0.5 | 0.8 | 1.3 | 2.0 |
| Placebo | 1.8 | 1.5 | 2.4 | 1.3 | 0.1 |
The LNPS is used for assessing pain intensity in neonates. Scores on the scale run from 0-14. Higher scores mean worse pain. (NCT01635101)
Timeframe: within 24 Hours
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| at 0 hours | at 6 hours | at 12 hours | at 18 hours | at 24 hours | |
| High Dose Acetaminophen | 0.8 | 1.0 | 1.8 | 1.8 | 1.3 |
| Low Dose Acetaminophen | 0.8 | 1.1 | 2.2 | 1.0 | 0.8 |
| Placebo | 1.1 | 1.2 | 2.0 | 0.8 | 0.9 |
The LNPS is used for assessing pain intensity in younger infants. Scores on the scale run from 0-14. Higher scores mean worse pain. (NCT01635101)
Timeframe: within 24 hours
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| at 0 hours | at 6 hours | at 12 hours | at 18 hours | at 24 hours | |
| High Dose Acetaminophen | 1.5 | 1.3 | 1.8 | 1.7 | 1.3 |
| Low Dose Acetaminophen | 2.1 | 2.1 | 2.2 | 1.6 | 2.3 |
| Placebo | 2.2 | 2.4 | 1.9 | 2.1 | 2.9 |
Time in PACU (NCT03558555)
Timeframe: up to 24 hours after PACU arrival
| Intervention | minutes (Mean) |
|---|---|
| Oral Acetaminophen | 82.93 |
| Acetaminophen IV Soln | 64.05 |
home opiod use (NCT03558555)
Timeframe: average 7 days
| Intervention | MME (Mean) |
|---|---|
| Oral Acetaminophen | 14.06 |
| Acetaminophen IV Soln | 17.56 |
Patient satisfaction total scale from 1 to 10, with higher score indicating more satisfaction (NCT03558555)
Timeframe: 7 days post surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Oral Acetaminophen | 5.05 |
| Acetaminophen IV Soln | 6.20 |
Total Morphine Milligram Equivalent (MME) use intraoperatively (NCT03558555)
Timeframe: Day 1
| Intervention | MME (Mean) |
|---|---|
| Oral Acetaminophen | 63.75 |
| Acetaminophen IV Soln | 57.24 |
Total narcotic use in PACU expressed in total morphine milligram equivalents (MME) (NCT03558555)
Timeframe: Day 1
| Intervention | MME (Mean) |
|---|---|
| Oral Acetaminophen | 11.33 |
| Acetaminophen IV Soln | 9.83 |
Post-Anesthesia Care Unity (PACU) pain scores at baseline, 1 hour, and on discharge from PACU. Pain score by visual analogue score, total scale from 0 to 10 with 10 being the worse pain. (NCT03558555)
Timeframe: baseline, 1 hour, and Day 1 discharge
| Intervention | score on a scale (Mean) | ||||
|---|---|---|---|---|---|
| Baseline | 1 hour | Discharge from PACU, up to 2.5 hours | 6 hour post op | 24 hour post op | |
| Acetaminophen IV Soln | 1.52 | 2.41 | 1.59 | 4.27 | 4.16 |
| Oral Acetaminophen | 2.13 | 2.88 | 1.45 | 3.82 | 3.64 |
Compare the percentage of patients using non-opioid pain medication at 24 hours, and 48 hours and had experienced any adverse events. (NCT02069184)
Timeframe: For the first 24 hours after the c-section until the patient is discharged or up to 48 hours
| Intervention | percentage of patients (Number) |
|---|---|
| IV Acetaminophen | 27 |
| Saline as Placebo | 30.3 |
Sedation was assessed on a scale of 1-3 (1= wide awake, 2= sleepy but easily aroused, 3= sleepy and difficult to arouse). These assessments were made at the same time points as the pain assessments by the same research assistant. Score 1 is the only good outcome. (NCT02069184)
Timeframe: Percentage of Participants Reporting to be Wide Awake up to 72 hours after the C-section
| Intervention | percentage of patients (Number) |
|---|---|
| IV Acetaminophen | 95 |
| Saline as Placebo | 95 |
No patients were re hospitalized in the first 7 days (NCT02069184)
Timeframe: From time of discharge to 1 week after discharge
| Intervention | percentage of patients (Number) |
|---|---|
| IV Acetaminophen | 0 |
| Saline as Placebo | 0 |
Subjects were specifically asked about adverse events such as nausea, vomiting, pruritus and breathing difficulties and information regarding their bowel movements. This information was collected on a scale of none, mild, moderate or severe. These are categorical outcomes. (NCT02069184)
Timeframe: every 6 hours for the first 24 hours after the c-section and there after every 8 hours until the patient is discharged or upto 72 hours. Finally, 1 week after discharge.
| Intervention | percentage of patients (Number) | |||
|---|---|---|---|---|
| 24 hour nausea | 24 hour vomiting | 24 hour itching | 24 hour breathing difficulty | |
| IV Acetaminophen | 22 | 21 | 57 | 9 |
| Saline as Placebo | 27 | 27 | 63 | 6 |
(NCT02069184)
Timeframe: 24 and 48 hours after Cesarean Section
| Intervention | mg (Mean) | |
|---|---|---|
| 24 hours cumulative | 48 hours cumulative | |
| IV Acetaminophen | 44 | 58 |
| Saline as Placebo | 48 | 57 |
Post-operative pain was assessed using VAS pain scores (0-10 scale) with 10 being the worst (NCT02069184)
Timeframe: every 6 hours for the first 24 hours after the c-section and there after every 8 hours until the patient is discharged or up to 48 hours
| Intervention | scores on a scale (Mean) | |||||||
|---|---|---|---|---|---|---|---|---|
| 0 hr pain after CS | 6 hours after CS pain | 12 hours after CS | 18 hours after CS | 24 hours after CS | 32 hours after CS | 40 hours after CS | 48 hours after CS | |
| IV Acetaminophen | 2.2 | 3.4 | 1.2 | 3.1 | 4.0 | 3.1 | 2.0 | 3.2 |
| Saline as Placebo | 1.4 | 3.6 | 2.3 | 2.9 | 5.1 | 2.9 | 1.2 | 2.6 |
Assessment of the amount of narcotic use postoperatively at 2 weeks. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 2 weeks
| Intervention | morphine milligram equivalents (Mean) |
|---|---|
| Gabapentin | 167.2 |
| Control | 187.3 |
Assessment of the amount of narcotic use postoperatively at 24 hours. will use opioid equivalence table to convert all narcotic use to oxycodone equivalents (NCT02703259)
Timeframe: 24 hours
| Intervention | morphine milligram equivalents (Mean) |
|---|---|
| Gabapentin | 158.8 |
| Control | 175.0 |
"Assessment of the subject pain score postoperatively at 2 weeks. will use a numeric analog scale from 0-10.~The pain scale ranging from 0-10 with 0 representing No Pain and 10 representing the Worst Pain Possible" (NCT02703259)
Timeframe: 2 weeks
| Intervention | score on a scale (Mean) |
|---|---|
| Gabapentin | 1.3 |
| Control | 1.4 |
Pain score assesses patient subjective pain via patient reported numeric analogue scale, range 0-10 with 0 being no pain and 10 being severe pain. (NCT02703259)
Timeframe: 24 hours
| Intervention | score on a scale (Mean) |
|---|---|
| Gabapentin | 3.4 |
| Control | 3.4 |
Will assess for known symptoms of gabapentin postoperatively at 2 weeks. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 2 weeks
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Dizziness | Blurred vision | Somnolence | Difficulty walking | Tremulousness | Nausea | Vomiting | |
| Control | 8 | 3 | 21 | 5 | 2 | 7 | 1 |
| Gabapentin | 12 | 4 | 18 | 5 | 4 | 12 | 0 |
Will assess for known symptoms of gabapentin postoperatively at 24 hours. We will survey subjects regarding their experience of the following symptoms: dizziness/drowsiness, fatigue, loss of balance, blurry vision, tremulousness, swelling, nausea, vomiting, diarrhea, and allergic reaction (NCT02703259)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Dizziness | Blurred Vision | Somnolence | Difficulty walking | Tremulousness | Nausea | Vomiting | |
| Control | 8 | 4 | 23 | 11 | 6 | 25 | 15 |
| Gabapentin | 17 | 7 | 20 | 13 | 11 | 24 | 9 |
Participant global evaluation of study medication was performed at the 12-hour time point or immediately before taking the rescue medication. It was scored on a 6-point categorical scale where 0= Very poor, 1= Poor, 2= Fair, 3= Good, 4= Very Good and 5= Excellent. (NCT01559259)
Timeframe: 12 hour
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 1.0 |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 3.8 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 3.4 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 3.6 |
| Ibuprofen 400 mg | 3.5 |
Participants evaluated the time to first perceptible relief (confirmed by meaningful relief) by stopping the first stopwatch labelled 'first perceptible relief' at the moment they first began to experience any pain relief, if the participant also achieved meaningful relief by the end of the study. Stopwatch was active up to 12 hours after dosing or until stopped by the participant, or until the participant dropped out due to treatment failure (defined as participant taking rescue medication, or discontinuing due to lack of efficacy) prior to depressing the first stopwatch or until the time of withdrawal (discontinuation). (NCT01559259)
Timeframe: From 0 hour up to 12 hours post-dose
| Intervention | minutes (Median) |
|---|---|
| Placebo | NA |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 18.5 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 22.8 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 18.5 |
| Ibuprofen 400 mg | 24.9 |
"Participants evaluated time to meaningful relief by stopping a second stopwatch labelled as meaningful relief at the moment they first began to experience meaningful relief. Stopwatch was active up to 12 hours after dosing or until stopped by participant, or participant became treatment failure prior to depressing the second stopwatch. Treatment failure was defined as participant taking rescue medication, or discontinuing due to lack of efficacy." (NCT01559259)
Timeframe: From 0 hour up to 12 hours post-dose
| Intervention | minutes (Median) |
|---|---|
| Placebo | NA |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 44.5 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 54.1 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 45.9 |
| Ibuprofen 400 mg | 56.2 |
Time to treatment failure was defined as the time interval from the study drug administration up to the first documentation of treatment failure. Treatment failure was defined as taking the rescue medication or discontinuation of the participants from the study due to lack of efficacy, whichever came first. Participants were censored at 12 hours or at their final assessment time, whichever came first. (NCT01559259)
Timeframe: From 0 hour up to 12 hours post-dose
| Intervention | hours (Median) |
|---|---|
| Placebo | 1.6 |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 9.7 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 10.1 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 11.1 |
| Ibuprofen 400 mg | 10.4 |
SPRID4:Time-weighted sum of pain relief rating (PRR) and pain intensity difference (PID) based on 4 point categorical severity rating scale (PRID) over 8 hours.SPRID 0-8 score range:-8 (worst score) to 56 (best score).PRID: sum of PRR and PID at each time point.PRID score range:-1= worst score to 7= best score.PID4 was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [none] to 3 [severe]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 = severe pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID: -1 (worst score) to 3 (best score).PRR assessed on 5-point categorical scale with range:0 =no relief to 4 =complete relief. (NCT01559259)
Timeframe: From 0 hour up to 8 hours post-dose
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo | 5.0 |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 30.8 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 29.6 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 31.7 |
| Ibuprofen 400 mg | 28.8 |
Percentage of participants with confirmed first perceptible relief was reported. Participants evaluated the time to first perceptible relief (confirmed by meaningful relief) by stopping the first stopwatch labelled 'first perceptible relief' at the moment they first began to experience any pain relief, if the participant also achieved meaningful relief by the end of the study. Stopwatch was active up to 12 hours after dosing or until stopped by the participant, or until the participant dropped out due to treatment failure prior to depressing the first stopwatch or until the time of withdrawal (discontinuation). Treatment failure was defined as participant taking rescue medication, or discontinuing due to lack of efficacy. (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | percentage of participants (Number) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 26.7 | 73.3 | 88.9 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 18.3 | 66.7 | 83.9 | 86.0 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 28.1 | 77.5 | 88.8 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 |
| Ibuprofen 400 mg | 19.6 | 63.0 | 80.4 | 84.8 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 |
| Placebo | 3.3 | 10.0 | 16.7 | 16.7 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 | 20.0 |
"Percentage of participants with meaningful relief was reported. Participants evaluated time to meaningful relief by stopping a second stopwatch labeled meaningful relief at the moment they first began to experience meaningful relief. Stopwatch was active up to 12 hours after dosing or until stopped by participant, or participant became treatment failure prior to depressing the second stopwatch. Treatment failure was defined as participant taking rescue medication, or discontinuing due to lack of efficacy." (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | percentage of participants (Number) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hours | 0.5 hours | 1 hour | 1.5 hours | 2 hours | 3 hours | 4 hours | 5 hours | 6 hours | 7 hours | 8 hours | 9 hours | 10 hours | 11 hours | 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 1.1 | 33.3 | 65.6 | 81.1 | 85.6 | 90.0 | 90.0 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 | 91.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 1.1 | 23.7 | 54.8 | 69.9 | 77.4 | 81.7 | 83.9 | 84.9 | 86.0 | 87.1 | 88.2 | 88.2 | 88.2 | 88.2 | 88.2 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 3.4 | 22.5 | 67.4 | 77.5 | 84.3 | 88.8 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 | 89.9 |
| Ibuprofen 400 mg | 1.1 | 13.0 | 54.3 | 66.3 | 73.9 | 80.4 | 81.5 | 82.6 | 83.7 | 84.8 | 85.9 | 85.9 | 85.9 | 85.9 | 85.9 |
| Placebo | 0.0 | 0.0 | 3.3 | 6.7 | 10.0 | 10.0 | 13.3 | 13.3 | 16.7 | 16.7 | 16.7 | 16.7 | 20.0 | 20.0 | 20.0 |
Treatment failure was defined as taking the rescue medication or discontinuation of the participants from the study due to lack of efficacy, whichever came first. Participants were censored at 12 hours or at their final assessment time, whichever came first. Percentage of participants who had treatment failure were reported. (NCT01559259)
Timeframe: 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | percentage of participants (Number) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 2.2 | 2.2 | 2.2 | 3.3 | 4.4 | 8.9 | 17.8 | 28.9 | 40.0 | 51.1 | 57.8 | 64.4 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 2.2 | 6.5 | 8.6 | 9.7 | 14.0 | 18.3 | 20.4 | 23.7 | 33.3 | 46.2 | 53.8 | 57.0 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 4.5 | 5.6 | 6.7 | 7.9 | 10.1 | 14.6 | 15.7 | 25.8 | 36.0 | 42.7 | 48.3 | 50.6 |
| Ibuprofen 400 mg | 5.4 | 10.9 | 13.0 | 15.2 | 15.2 | 20.7 | 27.2 | 32.6 | 35.9 | 45.7 | 53.3 | 55.4 |
| Placebo | 43.3 | 73.3 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 | 80.0 |
PID11: baseline pain severity score minus pain severity score at a given time point. Pain intensity was assessed on an 11-point numerical pain severity rating scale. PID11 was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 =no pain to 10 =worst possible pain) from the baseline pain intensity scores (score range: 5 =moderate pain to 10 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID11: -5 (worst score) to 10 (best score). (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 1.0 | 3.0 | 4.7 | 5.3 | 5.5 | 5.7 | 5.5 | 5.3 | 4.6 | 3.9 | 3.1 | 2.5 | 1.9 | 1.6 | 1.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.8 | 2.5 | 4.2 | 5.0 | 5.3 | 5.5 | 5.4 | 5.1 | 4.8 | 4.2 | 3.5 | 2.7 | 2.1 | 1.7 | 1.5 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 0.9 | 2.6 | 4.5 | 5.3 | 5.6 | 5.7 | 5.6 | 5.3 | 5.0 | 4.2 | 3.2 | 2.8 | 2.5 | 2.0 | 1.7 |
| Ibuprofen 400 mg | 0.4 | 1.7 | 3.8 | 4.6 | 5.0 | 5.2 | 5.1 | 4.9 | 4.4 | 3.9 | 3.5 | 2.9 | 2.5 | 2.2 | 1.9 |
| Placebo | 0.1 | 0.2 | 0.1 | 0.0 | -0.1 | 0.1 | 0.3 | 0.2 | 0.4 | 0.3 | 0.3 | 0.5 | 0.6 | 0.6 | 0.7 |
PID4: baseline pain severity score minus pain severity score at a given time point. Pain intensity was assessed on a 4-point categorical pain severity rating scale. PID4 was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [no pain] to 3 [worst possible pain]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID4: -1 (worst score) to 3 (best score). (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 0.3 | 0.9 | 1.5 | 1.6 | 1.7 | 1.7 | 1.7 | 1.6 | 1.4 | 1.2 | 0.9 | 0.8 | 0.6 | 0.5 | 0.3 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.2 | 0.7 | 1.2 | 1.5 | 1.6 | 1.6 | 1.6 | 1.5 | 1.4 | 1.2 | 1.0 | 0.7 | 0.6 | 0.5 | 0.4 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 0.3 | 0.8 | 1.4 | 1.6 | 1.7 | 1.7 | 1.7 | 1.6 | 1.6 | 1.3 | 1.0 | 0.8 | 0.7 | 0.6 | 0.4 |
| Ibuprofen 400 mg | 0.2 | 0.5 | 1.1 | 1.4 | 1.5 | 1.6 | 1.6 | 1.5 | 1.3 | 1.2 | 1.0 | 0.8 | 0.7 | 0.6 | 0.5 |
| Placebo | 0.1 | 0.1 | 0.1 | 0.1 | 0.0 | 0.1 | 0.1 | 0.1 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.2 | 0.3 |
"Participants answered a question: how much relief do you have from your starting pain? on a 5-point categorical pain relief rating scale. Scale ranges from 0= no relief to 4= complete relief." (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 0.6 | 1.7 | 2.5 | 2.8 | 2.9 | 2.9 | 2.9 | 2.7 | 2.5 | 2.1 | 1.7 | 1.4 | 1.2 | 0.9 | 0.8 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.5 | 1.5 | 2.3 | 2.6 | 2.7 | 2.8 | 2.7 | 2.6 | 2.4 | 2.2 | 1.9 | 1.5 | 1.2 | 1.0 | 0.9 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 0.7 | 1.6 | 2.5 | 2.8 | 2.9 | 3.0 | 2.9 | 2.8 | 2.7 | 2.3 | 1.9 | 1.7 | 1.5 | 1.3 | 1.1 |
| Ibuprofen 400 mg | 0.4 | 1.1 | 2.1 | 2.5 | 2.6 | 2.7 | 2.7 | 2.6 | 2.4 | 2.1 | 1.9 | 1.7 | 1.4 | 1.3 | 1.2 |
| Placebo | 0.2 | 0.3 | 0.4 | 0.4 | 0.4 | 0.5 | 0.5 | 0.5 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 | 0.6 |
PRID4: sum of PID and PRR at each post-dose time points up to 12 hours. Score range for PRID: -1(worst score) to 7(best score). PID was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [no pain] to 3 [worst possible pain]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID4: -1 (worst score) to 3 (best score). PRR was assessed on a 5-point categorical pain relief rating scale which ranges from 0 =no relief to 4 =complete relief. (NCT01559259)
Timeframe: 0.25, 0.5, 1, 1.5, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12 hours post-dose
| Intervention | units on a scale (Mean) | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 0.25 hour | 0.5 hour | 1 hour | 1.5 hour | 2 hour | 3 hour | 4 hour | 5 hour | 6 hour | 7 hour | 8 hour | 9 hour | 10 hour | 11 hour | 12 hour | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 1.0 | 2.6 | 4.0 | 4.5 | 4.6 | 4.6 | 4.5 | 4.3 | 3.8 | 3.3 | 2.7 | 2.2 | 1.7 | 1.4 | 1.1 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 0.7 | 2.2 | 3.6 | 4.1 | 4.3 | 4.4 | 4.3 | 4.1 | 3.9 | 3.4 | 2.9 | 2.2 | 1.7 | 1.5 | 1.2 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 1.0 | 2.4 | 3.9 | 4.5 | 4.7 | 4.7 | 4.6 | 4.4 | 4.2 | 3.6 | 2.8 | 2.5 | 2.2 | 1.9 | 1.6 |
| Ibuprofen 400 mg | 0.6 | 1.6 | 3.2 | 3.9 | 4.2 | 4.3 | 4.2 | 4.1 | 3.7 | 3.3 | 3.0 | 2.5 | 2.1 | 1.9 | 1.7 |
| Placebo | 0.3 | 0.3 | 0.5 | 0.5 | 0.4 | 0.6 | 0.7 | 0.6 | 0.8 | 0.7 | 0.7 | 0.8 | 0.8 | 0.9 | 0.9 |
Pain intensity was assessed on an 11-point numerical pain severity rating scale. SPID11: Time-weighted sum of PID scores over 12 hours. SPID11 score range was -10 (worst score) to 20 (best score) for SPID 0-2, -30 (worst score) to 60 (best score) for SPID 0-6, -40 (worst score) to 80 (best score) for SPID 0-8, -60 (worst score) to 120 (best score) for SPID 0-12. PID was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 =no pain to 10 =worst possible pain) from the baseline pain intensity scores (score range: 5 =moderate pain to 10 =worst possible pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID: -5 (worst score) to 10 (best score). (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 8 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 8 hours | 0 to12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 8.8 | 29.9 | 36.9 | 44.0 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 8.0 | 28.8 | 36.5 | 44.5 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 8.6 | 30.1 | 37.6 | 46.5 |
| Ibuprofen 400 mg | 7.2 | 26.8 | 34.2 | 43.7 |
| Placebo | 0.1 | 1.1 | 1.8 | 4.1 |
Pain intensity was assessed on a 4-point categorical pain severity rating scale. SPID4: Time-weighted sum of PID over post-dose time points. SPID4 score range was -2 (worst score) to 6 (best score) for SPID 0-2, -6 (worst score) to 18 (best score) for SPID 0-6, -8 (worst score) to 24 (best score) for SPID 0-8, -12 (worst score) to 36 (best score) for SPID 0-12. PID was calculated by subtracting the pain intensity score at given post-dose time points (pain severity score range: 0 [none] to 3 [severe]) from the baseline pain intensity scores (score range: 2 =moderate pain to 3 = severe pain; as participants with baseline pain score of at least moderate were included in study). Total possible score range for PID: -1 (worst score) to 3 (best score). (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 8 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 8 hours | 0 to 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 2.7 | 9.1 | 11.2 | 13.3 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 2.4 | 8.5 | 10.7 | 12.9 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 2.7 | 9.3 | 11.6 | 14.1 |
| Ibuprofen 400 mg | 2.2 | 8.2 | 10.4 | 13.0 |
| Placebo | 0.1 | 0.7 | 1.0 | 2.0 |
TOTPAR: time-weighted sum of PRR scores over 2, 6, 8 and 12 hours. TOTPAR score range was 0 (worst score) to 8 (best score) for TOTPAR 0-2, 0 (worst score) to 24 (best score) for TOTPAR 0-6, 0 (worst score) to 32 (best score) for TOTPAR 0-8, 0 (worst score) to 48 (best score) for TOTPAR 0-12. PRR was assessed on a 5-point categorical pain relief rating scale where 0= No relief to 4= Complete relief. (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 8 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | |||
|---|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 8 hours | 0 to 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 4.7 | 15.7 | 19.6 | 23.9 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 4.3 | 14.8 | 18.9 | 23.4 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 4.7 | 16.0 | 20.2 | 25.8 |
| Ibuprofen 400 mg | 4.0 | 14.3 | 18.4 | 23.9 |
| Placebo | 0.7 | 2.8 | 4.0 | 6.4 |
SPRID4: Time-weighted sum of PRR and PID based on 4 point categorical pain severity rating scale (PRID) with score range: -2(worst score) to 14 (best score) for SPRID 0-2, -6 (worst score) to 42 (best score) for SPRID 0-6 and -12 (worst score) to 84 (best score) for SPRID 0-12. PRID: sum of PID and PRR at post-dose time point with score range: -1 (worst score) to 7 (best score). PID calculated by subtracting pain intensity score at post-dose time points (score range: 0 [none] to 3 [severe]) from baseline pain intensity scores (score range: 2 =moderate pain to 3 = severe pain; as participants with baseline score of at least moderate were included). PID total possible score range: -1 (worst score) to 3(best score). PRR assessed on 5-point categorical scale with range: 0 =no relief to 4 =complete relief. (NCT01559259)
Timeframe: 0 to 2 hours, 0 to 6 hours, 0 to 12 hours post-dose
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| 0 to 2 hours | 0 to 6 hours | 0 to 12 hours | |
| Ibuprofen 200 mg + Acetaminophen 500 mg | 7.4 | 24.8 | 37.2 |
| Ibuprofen 250 mg + Acetaminophen 500 mg | 6.7 | 23.3 | 36.3 |
| Ibuprofen 300 mg + Acetaminophen 500 mg | 7.4 | 25.3 | 39.9 |
| Ibuprofen 400 mg | 6.2 | 22.5 | 36.9 |
| Placebo | 0.9 | 3.5 | 8.4 |
Hypoxemia is measured as minutes with hypoxemia (Spo2 <90%) per hour of successful Spo2 monitoring. Patients will have nearly continuous pulseoximeter monitoring and recording. Data from the monitor will be downloaded daily for 48 hours postoperatively. (NCT02156154)
Timeframe: the initial 48 hours of postoperative monitoring or for the duration of hospitalization, if shorter.
| Intervention | min/h (Median) |
|---|---|
| Intravenous Acetaminophen | 0.7 |
| Intravenous 0.9% Sodium Chloride | 1.1 |
Fatigue scores were calculated on a scale of 1 to 10, with 1 being no fatigue and 10 being the worst fatigue imaginable. (NCT02156154)
Timeframe: Postoperative day 1
| Intervention | score on a scale (Mean) |
|---|---|
| Intravenous Acetaminophen | 5 |
| Intravenous 0.9% Sodium Chloride | 4.9 |
A low respiratory function event was defined as an episode of less than 40% of predicted minute ventilation for 2 minutes. (NCT02156154)
Timeframe: Initial 48 postoperative hours or duration of hospitalization (whichever comes first)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intravenous Acetaminophen | 52 |
| Intravenous 0.9% Sodium Chloride | 50 |
Patients were asked about postoperative nausea and vomiting in the postanesthesia care unit, at 4-hour intervals while awake through the remaining initial day of surgery, and on the first and second postoperative mornings. (NCT02156154)
Timeframe: Initial 48 postoperative hours or duration of hospitalization (whichever comes first)
| Intervention | Participants (Count of Participants) |
|---|---|
| Intravenous Acetaminophen | 140 |
| Intravenous 0.9% Sodium Chloride | 124 |
Sedation was estimated by the RASS score and recorded at 2-hour intervals by ward nurses per clinical routine during the initial 48 postoperative hours. The Richmond Agitation-Sedation Scale (RASS) is scored from -5 to +4, with -5 being unarousable, 0 being alert and calm, and +4 being combative. (NCT02156154)
Timeframe: Initial 48 postoperative hours or duration of hospitalization (whichever comes first)
| Intervention | score on a scale (Mean) |
|---|---|
| Intravenous Acetaminophen | -0.96 |
| Intravenous 0.9% Sodium Chloride | -0.89 |
Total opioid consumption over the initial 48 postoperative hours was extracted from patients' medical records and converted to intravenous morphine equivalents (NCT02156154)
Timeframe: Initial 48 postoperative hours
| Intervention | mg (Median) |
|---|---|
| Intravenous Acetaminophen | 50 |
| Intravenous 0.9% Sodium Chloride | 58 |
Treatment effect data are reported as ratios of geometric means (NCT02156154)
Timeframe: Initial 48 postoperative hours or duration of hospitalization (whichever comes first)
| Intervention | hours (Median) |
|---|---|
| Intravenous Acetaminophen | 2.2 |
| Intravenous 0.9% Sodium Chloride | 2.2 |
Pain scores were calculated on a visual analog scale of 0 to 10, with 0 being no pain and 10 being the most pain imaginable; time-weighted mean was calculated as the area under the curve of the pain score measurements divided by total measurement time. (NCT02156154)
Timeframe: Initial 48 postoperative hours or duration of hospitalization (whichever comes first)
| Intervention | score on a scale (Mean) |
|---|---|
| Intravenous Acetaminophen | 4.3 |
| Intravenous 0.9% Sodium Chloride | 4.4 |
Pain scores were calculated on a visual analog scale of 0 to 10, with 0 being no pain and 10 being the most pain imaginable; time weighted mean was calculated as the area under the curve of the pain score measurements divided by total measurement time. Pain was recorded at roughly 15-minute intervals in the postanesthesia care unit and at 4-hour intervals on surgical wards (NCT02156154)
Timeframe: Initial 48 postoperative hours or duration of hospitalization (whichever comes first)
| Intervention | score on a scale (Mean) |
|---|---|
| Intravenous Acetaminophen | 4.2 |
| Intravenous 0.9% Sodium Chloride | 4.4 |
Total anesthetic dose is measured in minimal alveolar concentration hours. (NCT02156154)
Timeframe: Induction to extubation (3 hours on average)
| Intervention | minimal alveolar concentration hours (Median) |
|---|---|
| Intravenous Acetaminophen | 2.9 |
| Intravenous 0.9% Sodium Chloride | 2.9 |
mg/L acetaminophen in the plasma at the end of surgery (NCT02994940)
Timeframe: at the end of surgery, about 1 hour after IV Dose
| Intervention | mg/L (Median) |
|---|---|
| Oral Acetaminophen | 22 |
| Intravenous Acetaminophen | 20 |
mg/L acetaminophen in the plasma 3 hours after IV study drug administration (NCT02994940)
Timeframe: Outcome will be measured 3hrs post first IV Dose
| Intervention | mg/L (Median) |
|---|---|
| Oral Acetaminophen | 18 |
| Intravenous Acetaminophen | 11 |
A secondary endpoint is the proportion of patients with pain scores in the severe pain range (7 or higher) on numeric pain rating scale of 0 to 10; higher score more severe. (NCT02994940)
Timeframe: 24 hrs period following surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Oral Acetaminophen | 15 |
| Intravenous Acetaminophen | 17 |
Total dose of opioid, in morphine equivalents, that the patient receives for breakthrough pain in the 24 hour period following surgery. (NCT02994940)
Timeframe: Within 24hrs
| Intervention | mcg/kg (Median) |
|---|---|
| Oral Acetaminophen | 147.6 |
| Intravenous Acetaminophen | 125.4 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 2.8 |
| Control Group | 2.9 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 2
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 2.5 |
| Control Group | 2.3 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 3
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.9 |
| Control Group | 2.1 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 4
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.5 |
| Control Group | 1.9 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 5
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.7 |
| Control Group | 1.6 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 6
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.5 |
| Control Group | 1.4 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: Average BPI score will be collected for postoperative day 7
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.3 |
| Control Group | 1.4 |
"The Brief Pain Inventory (BPI) Severity short form is a validated, patient-reported outcome measure that assesses pain over a 24-hour period. The Pain Severity score is calculated as a composite mean score using the degree of pain a patient experiences per day at its least, worst, average, and now. The score ranges from 0 to 10 (higher indicates more pain).~Keller S, Bann CM, Dodd SL, Schein J, Mendoza TR, Cleeland CS. Validity of the brief pain inventory for use in documenting the outcomes of patients with noncancer pain. Clin J Pain 2004. 20(5): 309-318." (NCT03783702)
Timeframe: BPI score will be collected at the preoperative visit
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 1.6 |
| Control Group | 1.0 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score was collected for postoperative day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 30.2 |
| Control Group | 29.4 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 2
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 27.0 |
| Control Group | 23.5 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 3
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 19.2 |
| Control Group | 22.5 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 4
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 14.1 |
| Control Group | 16.8 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 5
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 15.8 |
| Control Group | 15.0 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 6
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 13.9 |
| Control Group | 11.7 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for postoperative day 7
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 8.1 |
| Control Group | 10.1 |
"A 10-cm visual analog scale (VAS) will be used to assess pain severity.The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no pain with a score of 0 to worst imaginable pain, corresponding to a score of 100." (NCT03783702)
Timeframe: Average pain score will be collected for preoperative visit (the day before surgery)
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 12.4 |
| Control Group | 8.5 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected at the preoperative visit
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 0 |
| Control Group | 0 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 1
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 36.3 |
| Control Group | 38.9 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 2
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 23.0 |
| Control Group | 21.6 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 3
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 15.9 |
| Control Group | 12.9 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 4
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 9.3 |
| Control Group | 11.8 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 5
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 10.1 |
| Control Group | 7.8 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 6
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 6.5 |
| Control Group | 6.6 |
"A 10-cm visual analog scale (VAS) will be used to assess bleeding. The VAS is a continuous, patient-reported outcome measure determined using a horizontal 100-mm scale ranging from no bleeding with a score of 0 to continuous bleeding, corresponding to a score of 100." (NCT03783702)
Timeframe: Epistaxis severity will be collected for postoperative day 7
| Intervention | units on a scale (Mean) |
|---|---|
| Experimental Group | 4.6 |
| Control Group | 5.4 |
Patients kept a daily medication log and reported the number of doses consumed per day (650mg acetaminophen, 600mg ibuprofen, 5mg oxycodone). The mean number of medication doses per day was calculated for each treatment group. (NCT03783702)
Timeframe: Postoperative day 1 to 7
| Intervention | Average number of medication doses/day (Mean) | ||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Oxycodone POD1 | Oxycodone POD2 | Oxycodone POD3 | Oxycodone POD4 | Oxycodone POD5 | Oxycodone POD6 | Oxycodone POD7 | Acetaminophen POD1 | Acetaminophen POD2 | Acetaminophen POD3 | Acetaminophen POD4 | Acetaminophen POD5 | Acetaminophen POD6 | Acetaminophen POD7 | Ibuprofen POD1 | Ibuprofen POD2 | Ibuprofen POD3 | Ibuprofen POD4 | Ibuprofen POD5 | Ibuprofen POD6 | Ibuprofen POD7 | |
| Control Group | 0.6 | 0.4 | 0.3 | 0.3 | 0.3 | 0.1 | 0 | 2.1 | 1.9 | 1.6 | 1.5 | 1.3 | 1.1 | 0.6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 |
| Experimental Group | 0.3 | 0.1 | 0.1 | 0.1 | 0.1 | 0.1 | 0 | 2.0 | 1.8 | 1.3 | 1.0 | 0.9 | 0.9 | 0.6 | 0.6 | 0.5 | 0.4 | 0.3 | 0.4 | 0.3 | 0.2 |
Length of hospital stay (admission to discharge) will be collected. (NCT02046382)
Timeframe: 2-7 days
| Intervention | hours (Median) |
|---|---|
| IV Acetaminophen | 78 |
| Normal Saline | 78 |
Only outcome for nausea/emesis is reported. (NCT02046382)
Timeframe: 2-7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| IV Acetaminophen | 17 |
| Normal Saline | 9 |
Patients will have access to ibuprofen for mild to moderate pain. The amount consumed during inpatient stay will be collected. (NCT02046382)
Timeframe: 2-7 days
| Intervention | mg (Mean) |
|---|---|
| IV Acetaminophen | 4786 |
| Normal Saline | 5260 |
Total oxycodone (mg) for breakthrough pain during inpatient stay (NCT02046382)
Timeframe: approximately 2 - 7 days
| Intervention | mg (Mean) |
|---|---|
| IV Acetaminophen | 47.0 |
| Normal Saline | 65.0 |
Post-operative nausea will be monitored and measured through direct observation and nursing clinical record (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | participants (Number) |
|---|---|
| IV Acetaminophen | 13 |
| Control | 10 |
Number of participants who received intraoperative supplemental fentanyl. The decision to administer fentanyl is based on hemodynamic changes, such as increasing blood pressure and heart rate. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | participants (Number) |
|---|---|
| IV Acetaminophen | 9 |
| Control | 4 |
Postoperative vital signs (systolic and diastolic blood pressure, pulse, temperature, and respiratory rate) were measured at different time points up to 4 hours after surgery. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | mmHg (Mean) |
|---|---|
| IV Acetaminophen | 75 |
| Control | 78.3 |
Postoperative vital signs (systolic and diastolic blood pressure, pulse, temperature, and respiratory rate) were measured at different time points up to 4 hours after surgery. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | beats per minute (Mean) |
|---|---|
| IV Acetaminophen | 76.3 |
| Control | 80 |
Postoperative vital signs (systolic and diastolic blood pressure, pulse, temperature, and respiratory rate) were measured at different time points up to 4 hours after surgery. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | breaths per minute (Mean) |
|---|---|
| IV Acetaminophen | 17.4 |
| Control | 17.2 |
Postoperative vital signs (systolic and diastolic blood pressure, pulse, temperature, and respiratory rate) were measured at different time points up to 4 hours after surgery. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | mmHg (Mean) |
|---|---|
| IV Acetaminophen | 133 |
| Control | 144 |
Postoperative vital signs (systolic and diastolic blood pressure, pulse, temperature, and respiratory rate) were measured at different time points up to 4 hours after surgery. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | Fahrenheit (Mean) |
|---|---|
| IV Acetaminophen | 97.1 |
| Control | 97.4 |
The total amount of morphine utilized in Postoperative Acute Care Unit (PACU) will be recorded. One dose is a 1mg bolus of morphine. (NCT01608308)
Timeframe: During Postoperative Acute Care Unit (PACU) stay (up to 4 hours after surgery)
| Intervention | doses (Median) |
|---|---|
| IV Acetaminophen | 1.5 |
| Control | 2.5 |
VAS is a validated, self-reported data sheet assessing average pain intensity. Possible scores range from 0 (no pain) to 10 (highest level of pain). (NCT01608308)
Timeframe: 15 minutes and 120 minutes Post-Operatively
| Intervention | units on a scale (Median) | |
|---|---|---|
| 15 minutes (n=24, 26) | 120 minutes (n=7, 11) | |
| Control | 0 | 2 |
| IV Acetaminophen | 0 | 0 |
Number of non-opioid group members switching to receiving opioid medication - assessed via the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Non-opioid Pain Control | 7 |
Number of participants with emergency department or urgent care visits in 14 post-operative days - assessed via the electronic medical record and the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Opioid Pain Control | 8 |
| Non-opioid Pain Control | 11 |
Number of participants with hospitalizations after discharge in 14 days - assessed using the electronic medical record and the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Opioid Pain Control | 3 |
| Non-opioid Pain Control | 8 |
"Score assigned by the patient at the end of 14 post-operative days in the take-home pain diary using a Likert scale. Patients will respond to the following statement I am happy with the pain relief I received in the last 14 days with responses ranging from strongly agree to strongly disagree. The responses will be assigned a numerical value, from 0 (strongly disagree) to 4 (strongly agree), and the average value for all subjects in the group will be reported as the overall pain relief satisfaction. Higher scores mean a better outcome." (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | score on a scale (Mean) |
|---|---|
| Opioid Pain Control | 3.35 |
| Non-opioid Pain Control | 3.09 |
Number of post-operative phone calls to nursing staff, obtained using the electronic medical record. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | post-operative phone calls (Mean) |
|---|---|
| Opioid Pain Control | 0.35 |
| Non-opioid Pain Control | 0.47 |
In the take-home pain diary, patients will record the amount of medication taken for each dose. The mean value of these doses will be calculated and averaged within each group to determine the average dose of each analgesic used. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Milliliters (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 7.52 | 7.53 | 0.04 |
| Opioid Pain Control | 6.54 | 7.53 | 0.13 |
Average pain over 14 post-operative days before and after medications. This is quantified using the validated Wong-Baker FACES pain metric. Patients receive a take-home pain diary and for 14 days report their maximum pain both before and after taking pain medication. The mean of these pain ratings will be the primary outcome measure. The Wong-Baker FACES scale is from 0 (min) to 10 (max). A higher score indicates worse outcome/pain. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Score on a scale (Mean) | |
|---|---|---|
| Before | After | |
| Non-opioid Pain Control Group | 5.66 | 2.24 |
| Opioid Pain Control Group | 5.78 | 2.33 |
Using the results of the take-home pain diary, we will calculate the average number of days of use of each analgesic for each group. The last day after which there is no subsequent use of analgesic will define the end-point of the duration of use. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | days (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 8.64 | 8.75 | 0.45 |
| Opioid Pain Control | 8.61 | 8.49 | 2.62 |
Using the take-home pain diary, the total amount in mL of each analgesic used over 14 days by each patient in a group will be averaged and reported. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Milliliters (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 326.98 | 334.65 | 2.96 |
| Opioid Pain Control | 292.48 | 324.14 | 6.47 |
Proportion of patients who receive new opioid discharge prescriptions at discharge following a thyroidectomy or parathyroidectomy procedure. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 128 |
| Post-implementation Group | 28 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients who receive new opioid prescriptions from the surgeon's office within 7 days of surgery including discharge prescriptions. This outcome excludes continuation of previous, chronic opioid therapy. (NCT04955444)
Timeframe: Up to 7 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 0 |
| Post-implementation Group | 0 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding the recommended dose of 112.5 oral MMEs (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 52 |
| Post-implementation Group | 8 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid discharge prescriptions exceeding 5 days of therapy (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 27 |
| Post-implementation Group | 5 |
Proportion of thyroidectomy and parathyroidectomy postoperative patients with opioid prescriptions exceeding 50 oral MMEs/day when new, postoperative discharge prescriptions are added to existing opioid therapy (NCT04955444)
Timeframe: Up to 2 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Historical Control Group | 9 |
| Post-implementation Group | 0 |
Opioid Consumption will be monitored in the first 24 post-operative hours. All non-opioid analgesics are disallowed. Total opioid consumption was calculated based on morphine equivalents (MEs), where 1 mg of IV morphine was equivalent to 1 ME, and 1 mg IV hydromorphone was calculated as 7 MEs. (NCT01598701)
Timeframe: 24 hours post-operatively
| Intervention | Morphine Equivalents (Median) |
|---|---|
| Intravenous Acetaminophen | 11.0 |
| Placebo | 10.1 |
(NCT01598701)
Timeframe: From time of entry to PACU to time to meet PACU discharge criteria, an average of 12 minutes
| Intervention | minutes (Mean) |
|---|---|
| Intravenous Acetaminophen | 11.4 |
| Placebo | 13.5 |
(NCT01598701)
Timeframe: Time from of discontinuation of anesthetic to time of extubation, an average of 7 minutes
| Intervention | minutes (Median) |
|---|---|
| Intravenous Acetaminophen | 6 |
| Placebo | 8 |
Patients will be assessed for pain using a Visual Analogue Scale (VAS) Scale at set time points after surgery (0,1,2,4,8,12,16,20,24 hours post-operatively). The Visual Analogue Scale (VAS) scale was measured on a scale of 0 - 10 (0 = no pain, 1-3 = mild, 4-6 = moderate, 7-10 = severe). Higher values on the VAS represent a worse outcome. The two rows below report: 1. the average VAS score for the least amount of pain reported per group and 2. the average VAS score of the worst amount of pain reported per group. (NCT01598701)
Timeframe: 24 Hours Post-Operatively
| Intervention | units on a scale (Mean) | |
|---|---|---|
| Least amount of pain reported | Worst amount of pain reported | |
| Intravenous Acetaminophen | 1.4 | 6.3 |
| Placebo | 2.6 | 6.4 |
Patients will be monitored for 24 hours post-operatively to detect the incidence of any drug or opioid-related side effects. These side effects were not considered to be adverse events. (NCT01598701)
Timeframe: 24 Hours Post-Operatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Emesis | Itching | Dizziness | Drowsiness | |
| Intravenous Acetaminophen | 23 | 8 | 14 | 24 |
| Placebo | 20 | 5 | 14 | 19 |
The postoperative day that patients in each group took their last opioid, from the end of surgery up to 96 postoperative hours. (NCT03887650)
Timeframe: 0-96 postoperative hours
| Intervention | day (Median) |
|---|---|
| Liposomal Bupivacaine 1.3% | 4 |
| Bupivacaine 0.5% With Adjuncts | 4 |
From the date and time of admission to the date and time of discharge, Measured in hours. (NCT03887650)
Timeframe: From the date of admission until discharge, assessed up to 72 hours.
| Intervention | hour (Median) |
|---|---|
| Liposomal Bupivacaine 1.3% | 31.05 |
| Bupivacaine 0.5% With Adjuncts | 31.63 |
From block time to the first dose of opioids given, measured in hours. (NCT03887650)
Timeframe: from the time of the block injection until discharge, assessed up to 72 postoperative hours.
| Intervention | hours (Median) |
|---|---|
| Liposomal Bupivacaine 1.3% | 10.5667 |
| Bupivacaine 0.5% With Adjuncts | 12.025 |
Total opioids used for the first 120 postoperative hours after TSA, standardized to morphine milligram equivalents (MMEs) (NCT03887650)
Timeframe: Up to 120 postoperative hours
| Intervention | MME (Median) |
|---|---|
| Liposomal Bupivacaine 1.3% | 71.25 |
| Bupivacaine 0.5% With Adjuncts | 90.30 |
"The Motor function was assessed by shoulder abduction and elbow flexion using the Oxford scale of muscle strength grading (Muscle Grading Scores 0-5):~0= No detectable muscle contraction (visible or palpation)~Detectable contraction (visible or palpation), but no movement achieved~Limb movement achieved, but unable to move against gravity~Limb movement against the resistance of gravity~Limb movement against gravity and external resistance~Normal strength~The results were grouped to show the return of any movement at the PACU, Day 1, after Day 1 (day2-60), and on day 60. And the return of full movement between day 2 and 60 and at day 60, in addition to the missing data." (NCT03887650)
Timeframe: PACU, Day 1, after Day 1 (day 2 and 60), and at postoperative day 60.
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| Any movement in PACU | Any movement in day1 | Any movement after day1 | Any movement missing data | Return of full movement day 2-60 | Not yet by day 60 | Return of full movement missing data | |
| Bupivacaine 0.5% With Adjuncts | 11 | 3 | 29 | 2 | 31 | 6 | 8 |
| Liposomal Bupivacaine 1.3% | 1 | 4 | 38 | 2 | 32 | 3 | 10 |
Pain assessment is categorized as minimum, maximum, and average pain scores reported by patients using questions from the Modified Brief Pain Inventory-short form (MBPI-SF) during the following intervals; PACU-24, 24-48, 48-72, and 72-96 postoperative hours, and at day 60. This form collected minimum, maximum, and average on a numeric pain scale (0-10) where 0 is no pain and 10 is the worst pain. (NCT03887650)
Timeframe: 24, 24-48, 48-72, and 72-96 hours postoperation, and at day 60
| Intervention | units on a scale 0-10 (Median) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PACU | PACU-24 hours Minimum | PACU-24 hours Maximum | PACU-24 hours Average | 24-48 hours Minimum | 24-48 hours Maximum | 24-48 hours Average | 48-72 hours Minimum | 48-72 hours Maximum | 48-72 hours Average | 72-96 hours Minimum | 72-96 hours Maximum | 72-96 hours Average | 60 days postoperative Maximum | 60 days postoperative Average | 60 days postoperative Minimum | |
| Bupivacaine 0.5% With Adjuncts | 0.00 | 0.00 | 1.00 | 0.00 | 2.00 | 7.00 | 4.00 | 2.00 | 6.00 | 3.00 | 2.00 | 5.00 | 3.00 | 6.00 | 2.00 | 0.00 |
| Liposomal Bupivacaine 1.3% | 0.00 | 0.00 | 2.00 | 1.00 | 0.00 | 4.50 | 2.00 | 1.00 | 4.00 | 2.00 | 0.50 | 4.00 | 2.00 | 5.00 | 1.00 | 0.00 |
Opioid use was calculated using the Morphine MilliEquevalent per day, this was assessed daily during the postoperative period, 0-24, 24-48, 48-72, and 72-120 postoperative hours. (NCT03887650)
Timeframe: 0-24, 24-48, 48-72, and 72-120 postoperative hours.
| Intervention | MME/day (Median) | |||
|---|---|---|---|---|
| 0-24 hours | 24-48 hours | 48-72 hours | 72-120 hours | |
| Bupivacaine 0.5% With Adjuncts | 25.00 | 23.25 | 5.00 | 15.00 |
| Liposomal Bupivacaine 1.3% | 25.00 | 16.00 | 2.00 | 10.00 |
Patient overall satisfaction with pain control was assessed two times; on the fourth and the 60th postoperative days. It was assessed using a numeric scale (0-10) where 0 is very dissatisfied while 10 is extremely satisfied. The results indicated only the percentage of participants who reported a 10/10 satisfaction rate. (NCT03887650)
Timeframe: POD4 - 60 days
| Intervention | Participants (Count of Participants) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| POD472268834 | POD472268835 | POD6072268834 | POD6072268835 | |||||||||
| 10/10 | below 10 | Missing data | ||||||||||
| Liposomal Bupivacaine 1.3% | 32 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 24 | |||||||||||
| Liposomal Bupivacaine 1.3% | 9 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 17 | |||||||||||
| Liposomal Bupivacaine 1.3% | 4 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 1 | |||||||||||
| Liposomal Bupivacaine 1.3% | 27 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 28 | |||||||||||
| Liposomal Bupivacaine 1.3% | 12 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 13 | |||||||||||
| Liposomal Bupivacaine 1.3% | 5 | |||||||||||
Using the sensory assessment test, the results show the percentage of participants who had the return of first sensation and full sensation either on Day 1, after Day 1 (day 2 to 60), and at postoperative day 60. (NCT03887650)
Timeframe: Day 1, after Day 1 (day 2 to 60), and at postoperative day 60
| Intervention | Participants (Count of Participants) | |||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Full sensation72268834 | Full sensation72268835 | First sensation72268834 | First sensation72268835 | |||||||||||||
| Returned on day 1 after the block | Returned on day 2-60 | Not by day 60 | Missing data | |||||||||||||
| Liposomal Bupivacaine 1.3% | 11 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 11 | |||||||||||||||
| Liposomal Bupivacaine 1.3% | 27 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 27 | |||||||||||||||
| Liposomal Bupivacaine 1.3% | 0 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 2 | |||||||||||||||
| Liposomal Bupivacaine 1.3% | 7 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 5 | |||||||||||||||
| Liposomal Bupivacaine 1.3% | 35 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 33 | |||||||||||||||
| Liposomal Bupivacaine 1.3% | 9 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 10 | |||||||||||||||
| Bupivacaine 0.5% With Adjuncts | 0 | |||||||||||||||
| Liposomal Bupivacaine 1.3% | 1 | |||||||||||||||
On a distress scale of (0 -10) with 0 = not at all and 10 = very much distressed, the scores were gathered and the results are grouped to show the percentage of either the presence of distress (any positive score) or no distress, assessed at two times; at the PACU and the second postoperative day. (NCT03887650)
Timeframe: At PACU and Postoperative day 2
| Intervention | Participants (Count of Participants) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PACU distress72268834 | PACU distress72268835 | POD2 Distress72268834 | POD2 Distress72268835 | |||||||||
| No distress | any distress | Missing data | ||||||||||
| Liposomal Bupivacaine 1.3% | 31 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 31 | |||||||||||
| Liposomal Bupivacaine 1.3% | 14 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 14 | |||||||||||
| Liposomal Bupivacaine 1.3% | 0 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 0 | |||||||||||
| Liposomal Bupivacaine 1.3% | 32 | |||||||||||
| Liposomal Bupivacaine 1.3% | 12 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 12 | |||||||||||
| Liposomal Bupivacaine 1.3% | 1 | |||||||||||
| Bupivacaine 0.5% With Adjuncts | 2 | |||||||||||
The primary efficacy end point was narcotic consumption during the first 48 hours after craniotomy. Opioid usage was calculated by converting the amount of the narcotics taken by the patient into oral morphine equivalents (ME), which were totaled for each postoperative day. At 48 hours after surgery, patients who received IV acetaminophen in addition to our standardized pain protocol did not have a statistically significantly lower mean narcotic requirement, measured in ME, when compared with those in the placebo group. (NCT01948505)
Timeframe: 48 hours
| Intervention | Morphine Equivalents (Mean) |
|---|---|
| Experimental Group | 123.5 |
| Placebo Group | 134.2 |
"The time-adjusted Summed Pain Intensity Differences (SPIDs) of the VAS pain intensity scores up to 48 hours after the first dose of study medication.~This was calculated from the visual analogue scale (VAS) pain intensity scores recorded during the 48 hours double blind treatment period, with the last measure taken just prior to the final dose of blinded study medication. The visual analogue scale is 100mm long with 0= no pain and 100=worst pain imaginable. The Visual Analogue Scale It is expected that treatments which can provide superior analgesic effect will demonstrate a greater Summed Pain Intensity Difference." (NCT01420653)
Timeframe: 48 hours afte the first dose
| Intervention | score on a scale (Mean) |
|---|---|
| Maxigesic 325 | 31.56 |
| Acetaminophen | 17.71 |
| Ibuprofen | 23.18 |
| Placebo | 14.86 |
Cumulative opiate consumption (IV morphine equivalents) (NCT02487303)
Timeframe: 24 hours
| Intervention | mg (Mean) |
|---|---|
| Acetaminophen Intravenous | 2.9 |
| Acetaminophen Oral | 3.8 |
| No Acetaminophen | 5.7 |
Time patient meets discharge criteria will be recorded (NCT02487303)
Timeframe: 24 hours postoperative
| Intervention | hours (Mean) |
|---|---|
| Acetaminophen Intravenous | 48.4 |
| Acetaminophen Oral | 48.6 |
| No Acetaminophen | 50.5 |
Time to first opiate pain medicine requested by patient (NCT02487303)
Timeframe: 48 hours
| Intervention | hours (Mean) |
|---|---|
| Acetaminophen Intravenous | 25.3 |
| Acetaminophen Oral | 24.0 |
| No Acetaminophen | 21.3 |
"Visual Analog Scale (VAS) pain assessment with ambulation. The visual analog scale (VAS) is a validated, subjective measure for acute and chronic pain. Scores are recorded by making a handwritten mark on a 10-cm line that represents a continuum between no pain and worst pain. For pain intensity, the scale is most commonly anchored by no pain (score of 0) and pain as bad as it could be or worst imaginable pain (score of 100 [100-mm scale]) ." (NCT02487303)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Acetaminophen Intravenous | 37.8 |
| Acetaminophen Oral | 44.3 |
| No Acetaminophen | 50.8 |
"VAS or Visual Analog Score is a quantitative measure, in this study, of pain that the subject is currently experiencing. The VAS is presented as a straight line which measures 100mm. The subject is instructed to mark an 'X' through this line reflecting the amount of pain that they are currently experiencing. Zero would indicate no pain, while '100' would indicate the most severe pain ever. Thus the total range for this scale would be 0-100 mm. Higher values indicate more pain; lower value indicate less pain.~For this outcome measure, the VAS scores from Baseline and the VAS scores from 24 hours after the end of surgery are being used. The change from baseline in postoperative pain equals the 24 hour VAS score minus the baseline VAS score.~The Change from Baseline would be the 24-hour VAS score minus the Baseline VAS score. Higher values indicate more pain; lower values indicate less pain." (NCT02155738)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Vaginal Surgery - Placebo | 20.5 |
| Vaginal Surgery - IV Acetaminophen | 29.2 |
| Laparoscopic Surgery - Placebo | 20.7 |
| Laparoscopic Surgery - IV Acetaminophen | 20.1 |
Equianalgesic dosage tables will be used to convert intra- and postoperative narcotics into morphine equivalents to compare narcotic requirements for the first week after surgery. Higher numbers indicate higher narcotic usage. (NCT02155738)
Timeframe: First 24 hours
| Intervention | mg (Mean) |
|---|---|
| Vaginal Surgery - Placebo | 32.5 |
| Vaginal Surgery - IV Acetaminophen | 31.6 |
| Laparoscopic Surgery - Placebo | 47.4 |
| Laparoscopic Surgery - IV Acetaminophen | 44.5 |
"Interference of pain with physical, mental and social activities will be measured by the Patient Reported Outcomes Measures Information Systems-Pain Interference-Short Form 8a (PROMIS PI-SF-8a) administered on POD#7.~This instrument measures the self reported consequences of pain on relevant aspects of one's life. This scale is considered to be universal rather than disease specific. Each question has five response options ranging in value from 1-5. The total raw score for the scale is the sum of all values. The total raw score can range from 8-40. All questions much be answered to obtain a valid score.~A higher PROMIS score indicates more 'hurt' or pain." (NCT02155738)
Timeframe: 1 week
| Intervention | units on a scale (Mean) |
|---|---|
| Vaginal Surgery - Placebo | 18.4 |
| Vaginal Surgery - IV Acetaminophen | 22.0 |
| Laparoscopic Surgery - Placebo | 22.9 |
| Laparoscopic Surgery - IV Acetaminophen | 25.2 |
"Percentage of patients who achieved at least 50% of the maximum TOTPAR at 8 hours. In the present trial the achievable TOTPAR over 8 hours ranges between 0 and 32." (NCT02777970)
Timeframe: 8 hours post-dose
| Intervention | percentage of patients (Number) |
|---|---|
| Tramadol/Dexketoprofen | 47.7 |
| Tramadol/Paracetamol | 35.5 |
| Placebo | 5.3 |
Percentage of patients who achieve at least 30% of PI Reduction versus baseline Over 8 Hours Post-dose. Percentage change of PI is calculated using the baseline value minus the PI assessed at 8 hours post-dose divided for the baseline value, then multiplied for 100. (NCT02777970)
Timeframe: 8 hours post-dose
| Intervention | percentage of patients (Number) |
|---|---|
| Tramadol/Dexketoprofen | 40.0 |
| Tramadol/Paracetamol | 35.5 |
| Placebo | 9.9 |
Percentage of patients who required RM within the first over 8 hours post-dose. (NCT02777970)
Timeframe: 8 hours post-dose
| Intervention | percentage of patients (Number) |
|---|---|
| Tramadol/Dexketoprofen | 51.2 |
| Tramadol/Paracetamol | 55.0 |
| Placebo | 88.5 |
PGE of the study medication (measured according to a five-point VRS from 1 = poor to 5 = excellent) at 8 hours post-dose or whenever the patient uses Rescue Medication (RM). (NCT02777970)
Timeframe: 8 hours postdose
| Intervention | units on a scale (Mean) |
|---|---|
| Tramadol/Dexketoprofen | 3.6 |
| Tramadol/Paracetamol | 2.8 |
| Placebo | 1.5 |
"Time to confirmed FPPAR (time to onset of analgesia) - i.e. time to FPPAR if confirmed by experiencing Meaningful Pain Relief (MPAR)~FPPAR and MPAR assessed by using stopwatches:~'first perceptible' PAR (FPPAR), i.e, at the moment they first felt any PAR whatsoever;~'meaningful' PAR (MPAR, ie, when the relief from pain became meaningful to them)" (NCT02777970)
Timeframe: 2 hours post-dose
| Intervention | minutes (Median) |
|---|---|
| Tramadol/Dexketoprofen | 21 |
| Tramadol/Paracetamol | 24 |
"TOTPAR calculated as the weighted sum of the PAR scores, measured according to a 5-point VRS (Verbal Rating Scale) from 0=no relief to 4=complete relief, over 6 hours post-dose (TOTPAR6).~The TOTPAR6 ranges from a minimum of 0 to a maximum of 24." (NCT02777970)
Timeframe: 6 hours post-dose
| Intervention | 5-point Verbal Rating Scale (Mean) |
|---|---|
| Tramadol/Dexketoprofen | 13.0 |
| Tramadol/Paracetamol | 9.2 |
| Placebo | 1.9 |
This is the Apgar score of the newborn collected at 5 minutes. Range is from 0-10, with the higher scores meaning a better outcome. (NCT02922985)
Timeframe: 5 minutes after birth
| Intervention | score on a scale (Median) |
|---|---|
| Placebo Control Group | 9 |
| Multimodal Pain Regimen Group | 9 |
Time to discharge from hospital, measured in hours (NCT02922985)
Timeframe: From time of hospital admission to time of discharge home up to 168 hours.
| Intervention | hours (Median) |
|---|---|
| Placebo Control Group | 50.2 |
| Multimodal Pain Regimen Group | 50 |
neonate receipt of oxygen by nasal cannula or mechanical ventilation (NCT02922985)
Timeframe: after birth and before hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo Control Group | 0 |
| Multimodal Pain Regimen Group | 4 |
Rate of admission to the neonatal intensive care unit (NCT02922985)
Timeframe: after birth and before hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Placebo Control Group | 2 |
| Multimodal Pain Regimen Group | 6 |
Number of opioid pain tablets remaining on post-operative day #7 from hospital discharge as reported by patients (NCT02922985)
Timeframe: 7 days post delivery
| Intervention | Tablets (Median) |
|---|---|
| Placebo Control Group | 18 |
| Multimodal Pain Regimen Group | 19 |
Pain Score at 24 Hours Post Operatively, expressed on a pain scale from 0-10 with the higher score meaning worse pain (outcome). (NCT02922985)
Timeframe: 24 hours post-operatively
| Intervention | score on a scale (Median) |
|---|---|
| Placebo Control Group | 5 |
| Multimodal Pain Regimen Group | 6 |
Pain Score at 48 Hours Post-operatively, expressed on a pain scale from 0-10 with the higher score meaning worse pain (outcome). (NCT02922985)
Timeframe: 48 hours post-operatively
| Intervention | score on a scale (Median) |
|---|---|
| Placebo Control Group | 4 |
| Multimodal Pain Regimen Group | 3 |
Pain score at 6-12 hours post-operatively, expressed on a pain scale from 0-10 with the higher score meaning worse pain (outcome). (NCT02922985)
Timeframe: 6-12 hours post-operatively
| Intervention | score on a scale (Median) |
|---|---|
| Placebo Control Group | 6 |
| Multimodal Pain Regimen Group | 6 |
Time, in hours, to first administration of opioid pain medication post operatively (NCT02922985)
Timeframe: 48 hours post cesarean delivery
| Intervention | hours (Median) |
|---|---|
| Placebo Control Group | 6.05 |
| Multimodal Pain Regimen Group | 6.35 |
Every opioid intake by the patient in the first 48 hours after CD will be recorded and quantified in morphine milligram equivalents (NCT02922985)
Timeframe: 48 hours post cesarean delivery
| Intervention | morphine milligram equivalents (Median) |
|---|---|
| Placebo Control Group | 42 |
| Multimodal Pain Regimen Group | 49.5 |
Postoperative hemorrhage is defined as any history of bleeding occurring within the 14 day postoperative period. Hemorrhage will be stratified into 3 levels of severity. Level 1: includes children with a history of postoperative bleeding evaluated and/or treated by a physician in the emergency room, inpatient unit or operating room; Level 2: children requiring inpatient admission for postoperative bleeding regardless of the need for operative intervention; Level 3: children requiring inpatient admission and return to the operating room for control of post-tonsillectomy hemorrhage. (NCT01605903)
Timeframe: Data about post-tonsillectomy bleeding will be obtained after the end of a 14-day postoperative period.
| Intervention | Participants (Count of Participants) |
|---|---|
| Treatment With Ibuprofen | 10 |
| Treatment With Acetaminophen | 4 |
Length of time from the end of surgery to discharge home from the hospital, assessed up to 1 week. (NCT03052816)
Timeframe: Time from end of surgery to discharge home from hospital, assessed up to 1 week.
| Intervention | hours (Mean) |
|---|---|
| ICE T | 24.1 |
| STANDARD | 24.1 |
Number of participants with urinary retention (discharge home with foley) (NCT03052816)
Timeframe: Number of participants with urinary retention (discharge home with foley) measured on day patient is discharged home/study completion up to 1 week.
| Intervention | Participants (Count of Participants) |
|---|---|
| ICE T | 5 |
| STANDARD | 7 |
Number of patients with postoperative nausea and vomiting at 7AM after surgery (NCT03052816)
Timeframe: Postoperative nausea and vomiting from the time to end of surgery until 7AM after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| ICE T | 14 |
| STANDARD | 18 |
Quality of Recovery scores on post op day 1. The QoR-40 is a 40-item quality of recovery score measuring 5 dimensions: physical comfort (12 items), emotional state (9 items), physical independence (5 items), psychological support (7 items), and pain (7 items). Each item is rated on a 5-point Likert scale. The QoR-40 has a possible score of 40 (extremely poor quality of recovery) to 200 (excellent quality of recovery). It was specifically designed to measure a patient's health status after surgery and anesthesia, and it has been proposed as a measure of outcome in clinical trials. (NCT03052816)
Timeframe: Quality of Recovery scores on post op day 1
| Intervention | score on a scale (Median) |
|---|---|
| ICE T | 182 |
| STANDARD | 173 |
Satisfaction scores 96 hours after surgery. The satisfaction score is a numerical score from 0-10 with a score of 0 indicating very dissatisfied on the left of the scale and 10 indicating very satisfied on the right of the scale. (NCT03052816)
Timeframe: Satisfaction scores 96 hours after surgery
| Intervention | score on a scale (Median) |
|---|---|
| ICE T | 10 |
| STANDARD | 9 |
Satisfaction scores in the morning after surgery (7AM). The satisfaction score is a numerical score from 0-10 with a score of 0 indicating very dissatisfied on the left of the scale and 10 indicating very satisfied on the right of the scale. (NCT03052816)
Timeframe: Satisfaction scores in the morning after surgery (7AM)
| Intervention | score on a scale (Median) |
|---|---|
| ICE T | 10 |
| STANDARD | 10 |
Total dose of opioids administered during hospitalization in morphine equivalents upon hospital discharge. (NCT03052816)
Timeframe: Total dose of opioids administered during hospitalization in morphine equivalents from the end of surgery to discharge up to 1 week
| Intervention | milligrams of oral morphine equivalents (Mean) |
|---|---|
| ICE T | 55.7 |
| STANDARD | 91.2 |
VAS Scores 96 hours after surgery. The VAS is a 100mm scale with a score of no pain on the left of the scale, indicating a score of 0, and a score of worst pain on the right, indicating a score of 10. Patient is instructed to score the scale where they feel is appropriate. Each demarcation in between marks is 10mm and after the patient marks their score it is measured using mm from 0mm-100mm. A score of 0 is 0mm and a score of 10 is 100mm. (NCT03052816)
Timeframe: VAS Scores 96 hours after surgery
| Intervention | mm (Median) |
|---|---|
| ICE T | 20 |
| STANDARD | 30 |
VAS Scores at 4 hours post surgery. The VAS is a 100mm scale with a score of no pain on the left of the scale, indicating a score of 0, and a score of worst pain on the right, indicating a score of 10. Patient is instructed to score the scale where they feel is appropriate. Each demarcation in between marks is 10mm and after the patient marks their score it is measured using mm from 0mm-100mm. A score of 0 is 0mm and a score of 10 is 100mm. (NCT03052816)
Timeframe: VAS Scores at 4 hours post surgery
| Intervention | mm (Median) |
|---|---|
| ICE T | 35 |
| Standard | 50 |
Visual Analog Scores (VAS) Scores in the morning of post op day 1. The VAS is a 100mm scale with a score of no pain on the left of the scale, indicating a score of 0, and a score of worst pain on the right, indicating a score of 10. Patient is instructed to score the scale where they feel is appropriate. Each demarcation in between marks is 10mm and after the patient marks their score it is measured using mm from 0mm-100mm. A score of 0 is 0mm and a score of 10 is 100mm. (NCT03052816)
Timeframe: Visual Analog Scores (VAS) Score in the morning of post op day 1 at 7am.
| Intervention | mm (Median) |
|---|---|
| ICE T | 20 |
| Standard | 40 |
"Assess anxiety by hospital anxiety depression scale survey~This 14-component scoring system is used to tabulate a total sum score (0-42) or separate anxiety and depression scores (0-21). A higher score represents a more severe degree of anxiety and/or depression. The severity of a patient's anxiety or depression may then be grouped into three categories based on the score (Normal, 0-7; Borderline abnormal, 8-10; Abnormal 11-21)." (NCT03093454)
Timeframe: Pre-operatively, Post-op Day 1 (POD1), Final Post-op Day (Final POD)
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| Pre-operative | Post-op Day 1 (POD1) | Final Post-op Day (Final POD) | |
| Control Group | 14.9 | 14.8 | 15.8 |
| Lavender Group | 14.4 | 15.0 | 15.7 |
"Assess pain through pain scores documented in medical record compared to control group.~Pain score of 0 is no pain versus pain score of 10 is highest pain possible." (NCT03093454)
Timeframe: Pre-operatively, Post-op Day 1 (POD1), and final post-op day (final POD)
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Preoperative | Post-op Day 1 (POD1) | Final Post-op Day (final POD) | |
| Control Group | 0.5 | 3.5 | 2.5 |
| Lavender Group | 0.9 | 3.1 | 2.9 |
Assess sleep quality by Richards Campbell sleep questionnaire survey A score of zero (0) minimal if any sleep at all versus 10 deep and sound sleeping during hospital stay. (NCT03093454)
Timeframe: Pre-operatively, Post-op Day 1(POD1), and final Post-op Day (final POD)
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Pre-operative | Post-op Day 1 (POD1) | Final Post-op Day (Final POD) | |
| Control Group | 6.5 | 5.5 | 6.6 |
| Lavender Group | 5.6 | 5.1 | 7.4 |
Anxiety was measured using a visual analogue scale, from 0-10 cm. All measurements were rounded to the nearest 0.5 cm. Higher values indicate more anxiety. (NCT02344745)
Timeframe: 15 min after removal of the urodynamics catheters
| Intervention | cm (Median) |
|---|---|
| Control | 0.5 |
| Lavender | 0 |
Anxiety was measured using a visual analogue scale, from 0-10 cm. All measurements were rounded to the nearest 0.5 cm. Higher values indicate more anxiety. (NCT02344745)
Timeframe: At the time of catheter placement
| Intervention | cm (Median) |
|---|---|
| Control | 4 |
| Lavender | 3 |
Pain was measured on the Wong Baker scale from 0-10. Higher values indicate more pain. (NCT02344745)
Timeframe: 15 min after removal of the urodynamics catheters
| Intervention | units on a scale (Median) |
|---|---|
| Control | 0 |
| Lavender | 0 |
Pain was measured on the Wong Baker scale from 0-10. Higher values indicate more pain. (NCT02344745)
Timeframe: At the time of catheter placement
| Intervention | units on a scale (Median) |
|---|---|
| Control | 0 |
| Lavender | 0 |
PGART was measured by a score in a scale from 0-4: 0- Poor; 1- Fair 2- Good; 3- Very Good; 4- Excellent. (NCT01082081)
Timeframe: Baseline to 6 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 1.54 |
| Paracetamol Caplet 500 mg | 1.24 |
| Placebo Caplet | 0.63 |
Percentage of participants who took rescue medication during 2 to 6 hours (NCT01082081)
Timeframe: Within 2 to 6 hours post dose
| Intervention | Percentage of participants (Number) |
|---|---|
| Paracetamol Caplet 1000 mg | 57.9 |
| Paracetamol Caplet 500 mg | 55.5 |
| Placebo Caplet | 53.3 |
Percentage of participants who received rescue medication within 2 hours (NCT01082081)
Timeframe: Baseline to 2 hours post dose
| Intervention | Percentage of participants (Number) |
|---|---|
| Paracetamol Caplet 1000 mg | 5.00 |
| Paracetamol Caplet 500 mg | 11.80 |
| Placebo Caplet | 18.30 |
"SPID was calculated as sum of products of Pain Intensity Differences (PID) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240. Positive and higher scores indicate greater reduction in pain.~SPIDt = ∑PID x (timet - timet-1)~Pain Intensity was assessed at baseline and at each time-point based on a 4-point categorical Verbal Rating Scale (VRS) scale: 0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain.~If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from pain scores taken at baseline." (NCT01082081)
Timeframe: Every two hours from baseline to 4 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 2.0 |
| Paracetamol Caplet 500 mg | 0.7 |
| Placebo Caplet | -0.5 |
"SPID was calculated as sum of products of Pain Intensity Differences (PID) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240, 240-300 and 300-360. Positive and higher scores indicate greater reduction in pain.~SPIDt = ∑PID x (timet - timet-1)~Pain Intensity was assessed at baseline and at each time-point based on a 4-point categorical Verbal Rating Scale (VRS) scale: 0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain.~If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from pain scores taken at baseline." (NCT01082081)
Timeframe: Every two hours from baseline to 6 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 2.6 |
| Paracetamol Caplet 500 mg | 0.7 |
| Placebo Caplet | -0.8 |
SPRID:Sum of Pain Intensity Difference (SPID) and Total Pain Relief (TOTPAR) at each post-dosing time-point. SPRID score ranged from -1.8 (least pain relief) to 12.3 (highest pain relief). SPID and TOTPAR were calculated as weighted sums of Pain Intensity Differences (PID) and Pain Relief Scores (PRS) at each measurement time, respectively. PID was derived by subtracting the pain severity score at a given post-dosing time-point from the baseline [pain severity score range:0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain using a 4-point categorical Verbal Rating Scale (VRS)]. If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from baseline pain scores. PRS was assessed on 5-point categorical pain relief rating scale [0-no relief, 1-little relief, 2-some relief, 3-a lot of relief, 4-complete relief] (NCT01082081)
Timeframe: Every two hours from baseline to 2 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 4.62 |
| Paracetamol Caplet 500 mg | 3.26 |
| Placebo Caplet | 1.49 |
SPRID:Sum of Pain Intensity Difference (SPID) and Total Pain Relief (TOTPAR) at each post-dosing time-point. SPRID score ranged from -3.8 (least pain relief) to 26.3 (highest pain relief). SPID and TOTPAR were calculated as weighted sums of Pain Intensity Differences (PID) and Pain Relief Scores (PRS) at each measurement time, respectively. PID was derived by subtracting the pain severity score at a given post-dosing time-point from the baseline [pain severity score range:0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain using a 4-point categorical Verbal Rating Scale (VRS)]. If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from baseline pain scores. PRS was assessed on 5-point categorical pain relief rating scale [0-no relief, 1-little relief, 2-some relief, 3-a lot of relief, 4-complete relief] (NCT01082081)
Timeframe: Every two hours from baseline to 4 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 7.82 |
| Paracetamol Caplet 500 mg | 4.42 |
| Placebo Caplet | 2.07 |
"SPID was calculated as sum of products of Pain Intensity Differences (PID) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120. Positive and higher scores indicate greater reduction in pain.~SPIDt = ∑PID x (timet - timet-1)~Pain Intensity was assessed at baseline and at each time-point based on a 4-point categorical Verbal Rating Scale (VRS) scale: 0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain.~If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from pain scores taken at baseline." (NCT01082081)
Timeframe: Every two hours from baseline to 2 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 1.3 |
| Paracetamol Caplet 500 mg | 0.8 |
| Placebo Caplet | 0.0 |
SPRID:Sum of Pain Intensity Difference (SPID) and Total Pain Relief (TOTPAR) at each post-dosing time-point. SPRID score ranged from -5.8 (least pain relief) to 40.3 (highest pain relief). SPID and TOTPAR were calculated as weighted sums of Pain Intensity Differences (PID) and Pain Relief Scores (PRS) at each measurement time, respectively. PID was derived by subtracting the pain severity score at a given post-dosing time-point from the baseline [pain severity score range:0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain using a 4-point categorical Verbal Rating Scale (VRS)]. If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from baseline pain scores. PRS was assessed on 5-point categorical pain relief rating scale [0-no relief, 1-little relief, 2-some relief, 3-a lot of relief, 4-complete relief] (NCT01082081)
Timeframe: Every two hours from baseline to 6 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 10.60 |
| Paracetamol Caplet 500 mg | 5.87 |
| Placebo Caplet | 3.35 |
Participants recorded the time to first perceptible relief by starting the first stopwatch at the time of dosing and stopping it when he/she experienced the first perceptible pain relief. The first perceptible pain relief was confirmed if the participant also stopped the second stopwatch indicating meaningful relief. (NCT01082081)
Timeframe: Baseline to 6 hours post dose
| Intervention | minutes (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 80.63 |
| Paracetamol Caplet 500 mg | 119.10 |
| Placebo Caplet | 189.53 |
Participants evaluated the time to meaningful relief by stopping a second stopwatch when they first began to experience meaningful relief. (NCT01082081)
Timeframe: Baseline to 6 hours post dose
| Intervention | minutes (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 96.44 |
| Paracetamol Caplet 500 mg | 129.75 |
| Placebo Caplet | 207.67 |
Median time of use of rescue medication by participants was calculated. (NCT01082081)
Timeframe: Baseline to 6 hours post dose
| Intervention | minutes (Median) |
|---|---|
| Paracetamol Caplet 1000 mg | 242.00 |
| Paracetamol Caplet 500 mg | 189.00 |
| Placebo Caplet | 148.00 |
"TOTPAR was calculated as sum of products of pain relief (PR) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120. Higher score indicated greater pain relief.~TOTPARt = ∑PR x (timet - timet-1).~PR score was assessed at each of the above time-points based on a 5-point categorical scale [0-no relief, 1-little relief, 2-meaningful relief, 3-a lot of relief, 4-complete relief]." (NCT01082081)
Timeframe: Every two hours from baseline to 2 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 3.33 |
| Paracetamol Caplet 500 mg | 2.46 |
| Placebo Caplet | 1.47 |
"TOTPAR was calculated as sum of products of pain relief (PR) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240. Higher score indicated greater pain relief.~TOTPARt = ∑PR x (timet - timet-1).~PR score was assessed at each of the above time-points based on a 5-point categorical scale [0-no relief, 1-little relief, 2-meaningful relief, 3-a lot of relief, 4-complete relief]." (NCT01082081)
Timeframe: Every two hours from baseline to 4 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 5.82 |
| Paracetamol Caplet 500 mg | 3.73 |
| Placebo Caplet | 2.55 |
"TOTPAR was calculated as sum of products of pain relief (PR) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240, 240-300 and 300-360. Higher score indicated greater pain relief.~TOTPARt = ∑PR x (timet - timet-1).~PR score was assessed at each of the above time-points based on a 5-point categorical scale [0-no relief, 1-little relief, 2-meaningful relief, 3-a lot of relief, 4-complete relief]." (NCT01082081)
Timeframe: Every two hours from baseline to 6 hours post dose
| Intervention | Units on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000 mg | 8.05 |
| Paracetamol Caplet 500 mg | 5.18 |
| Placebo Caplet | 4.10 |
PGART was measured by a score in a scale from 0-4: 0- Poor; 1- Fair 2- Good; 3- Very Good; 4- Excellent. (NCT01075243)
Timeframe: Baseline to 6 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 2.20 |
| Paracetamol Caplet 650 mg | 1.80 |
| Placebo Caplet | 0.80 |
Percentage of participants who received rescue medication at different time points post dose. (NCT01075243)
Timeframe: Baseline to 2 hours post dose
| Intervention | Percentage of participants (Number) |
|---|---|
| Paracetamol Caplet 1000mg | 0.00 |
| Paracetamol Caplet 650 mg | 0.00 |
| Placebo Caplet | 1.30 |
Percentage of participants who received rescue medication at different time points post dose. (NCT01075243)
Timeframe: Baseline to 6 hours post dose
| Intervention | Percentage of participants (Number) |
|---|---|
| Paracetamol Caplet 1000mg | 44.20 |
| Paracetamol Caplet 650 mg | 51.90 |
| Placebo Caplet | 70.00 |
"SPID was calculated as sum of products of Pain Intensity Differences (PID) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240. Positive and higher scores indicate greater reduction in pain.~SPIDt = ∑PID x (timet - timet-1)~Pain Intensity was assessed at baseline and at each time-point based on a 4-point categorical Verbal Rating Scale (VRS) scale: 0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain.~If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from pain scores taken at baseline." (NCT01075243)
Timeframe: Every two hours from baseline to 4 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 3.88 |
| Paracetamol Caplet 650 mg | 2.81 |
| Placebo Caplet | 0.20 |
"SPID was calculated as sum of products of Pain Intensity Differences (PID) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240, 240-300 and 300-360. Positive and higher scores indicate greater reduction in pain.~SPIDt = ∑PID x (timet - timet-1)~Pain Intensity was assessed at baseline and at each time-point based on a 4-point categorical Verbal Rating Scale (VRS) scale: 0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain.~If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from pain scores taken at baseline." (NCT01075243)
Timeframe: Every two hours from baseline to 6 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 5.02 |
| Paracetamol Caplet 650 mg | 3.59 |
| Placebo Caplet | 0.34 |
SPRID:Sum of Pain Intensity Difference (SPID) and Total Pain Relief (TOTPAR) at each post-dosing time-point. SPRID score ranged from -1.8 (least pain relief) to 12.3 (highest pain relief). SPID and TOTPAR were calculated as weighted sums of Pain Intensity Differences (PID) and Pain Relief Scores (PRS) at each measurement time, respectively. PID was derived by subtracting the pain severity score at a given post-dosing time-point from the baseline [pain severity score range:0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain using a 4-point categorical Verbal Rating Scale (VRS)]. If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from baseline pain scores. PRS was assessed on 5-point categorical pain relief rating scale [0-no relief, 1-little relief, 2-some relief, 3-a lot of relief, 4-complete relief (NCT01075243)
Timeframe: Every two hours from baseline to 2 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 6.49 |
| Paracetamol Caplet 650 mg | 5.57 |
| Placebo Caplet | 1.55 |
SPRID:Sum of Pain Intensity Difference (SPID) and Total Pain Relief (TOTPAR) at each post-dosing time-point. SPRID score ranged from -3.8 (least pain relief) to 26.3 (highest pain relief). SPID and TOTPAR were calculated as weighted sums of Pain Intensity Differences (PID) and Pain Relief Scores (PRS) at each measurement time, respectively. PID was derived by subtracting the pain severity score at a given post-dosing time-point from the baseline [pain severity score range:0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain using a 4-point categorical Verbal Rating Scale (VRS)]. If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from baseline pain scores. PRS was assessed on 5-point categorical pain relief rating scale [0-no relief, 1-little relief, 2-some relief, 3-a lot of relief, 4-complete relief (NCT01075243)
Timeframe: Every two hours from baseline to 4 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 12.09 |
| Paracetamol Caplet 650 mg | 9.45 |
| Placebo Caplet | 3.00 |
"SPID was calculated as sum of products of Pain Intensity Differences (PID) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120. Positive and higher scores indicate greater reduction in pain.~SPIDt = ∑PID x (timet - timet-1)~Pain Intensity was assessed at baseline and at each time-point based on a 4-point categorical Verbal Rating Scale (VRS) scale: 0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain.~If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from pain scores taken at baseline." (NCT01075243)
Timeframe: Every two hours from baseline to 2 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 2.17 |
| Paracetamol Caplet 650 mg | 1.77 |
| Placebo Caplet | 0.19 |
SPRID:Sum of Pain Intensity Difference (SPID) and Total Pain Relief (TOTPAR) at each post-dosing time-point. SPRID score ranged from -5.8 (least pain relief) to 40.3 (highest pain relief). SPID and TOTPAR were calculated as weighted sums of Pain Intensity Differences (PID) and Pain Relief Scores (PRS) at each measurement time, respectively. PID was derived by subtracting the pain severity score at a given post-dosing time-point from the baseline [pain severity score range:0-no pain, 1-mild pain, 2-moderate pain, 3-severe pain using a 4-point categorical Verbal Rating Scale (VRS)]. If the subject rated pain intensity as 2 or 3, pain was assessed using a 100 mm Visual Analog Scale (VAS) [0 (no pain), 100 (worst pain)]. VAS scores were converted into PID scores by subtracting them from baseline pain scores. PRS was assessed on 5-point categorical pain relief rating scale [0-no relief, 1-little relief, 2-some relief, 3-a lot of relief, 4-complete relief] (NCT01075243)
Timeframe: Every two hours from Baseline to 6 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 16.08 |
| Paracetamol Caplet 650 mg | 12.42 |
| Placebo Caplet | 4.63 |
Participants recorded the time to first perceptible relief by starting the first stopwatch at the time of dosing and stopping it when he/she experienced the first perceptible pain relief. The first perceptible pain relief was confirmed if the participant also stopped the second stopwatch indicating meaningful relief. (NCT01075243)
Timeframe: Baseline to 6 hours post dose
| Intervention | minutes (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 54.72 |
| Paracetamol Caplet 650 mg | 69.67 |
| Placebo Caplet | 225.70 |
Participants recorded the time to meaningful relief by stopping a second stopwatch when they first began to experience meaningful relief. (NCT01075243)
Timeframe: Baseline to 6 hours post dose
| Intervention | minutes (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 70.53 |
| Paracetamol Caplet 650 mg | 88.16 |
| Placebo Caplet | 247.14 |
Median time of use of rescue medication by participants. (NCT01075243)
Timeframe: Baseline to 6 hours post dose
| Intervention | minutes (Median) |
|---|---|
| Paracetamol Caplet 1000 mg | 360.00 |
| Paracetamol Caplet 650 mg | 314.00 |
| Placebo Caplet | 131.00 |
"TOTPAR was calculated as sum of products of pain relief (PR) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120. Higher score indicated greater pain relief.~TOTPARt = ∑PR x (timet - timet-1).~PR score was assessed at each of the above time-points based on a 5-point categorical scale [0-no relief, 1-little relief, 2-meaningful relief, 3-a lot of relief, 4-complete relief]." (NCT01075243)
Timeframe: Every two hours from baseline to 2 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 4.31 |
| Paracetamol Caplet 650 mg | 3.80 |
| Placebo Caplet | 1.36 |
"TOTPAR was calculated as sum of products of pain relief (PR) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240. Higher score indicated greater pain relief.~TOTPARt = ∑PR x (timet - timet-1).~PR score was assessed at each of the above time-points based on a 5-point categorical scale [0-no relief, 1-little relief, 2-meaningful relief, 3-a lot of relief, 4-complete relief]." (NCT01075243)
Timeframe: Every two hours from baseline to 4 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 8.21 |
| Paracetamol Caplet 650 mg | 6.64 |
| Placebo Caplet | 2.79 |
"TOTPAR was calculated as sum of products of pain relief (PR) at a given time-point (t) with the time-interval from that time-point to the previous time-point (t-1). The time-intervals used were 0-15, 15-30, 30-45, 45-60, 60-90, 90-120, 120-240, 240-300 and 300-360. Higher score indicated greater pain relief.~TOTPARt = ∑PR x (timet - timet-1).~PR score was assessed at each of the above time-points based on a 5-point categorical scale [0-no relief, 1-little relief, 2-meaningful relief, 3-a lot of relief, 4-complete relief]." (NCT01075243)
Timeframe: Every two hours from baseline to 6 hours post dose
| Intervention | Score on a scale (Mean) |
|---|---|
| Paracetamol Caplet 1000mg | 11.06 |
| Paracetamol Caplet 650 mg | 8.83 |
| Placebo Caplet | 4.29 |
Numeric Rating Pain Scores ( 0-10), will be obtained every 2 hours after PACU discharge up to 18 hours or until hospital discharge, whichever occurs first. The pain score of 0, means no pain, is a good outcome , and a pain score of 10 is excruciating pain, a very bad outcome. The average of these scores will be evaluated.The pain scores will not longer be documented after the numbness went away. (NCT02439281)
Timeframe: Logistic regression of the 4 th pain score assessment
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine Group | 2 |
| Ropivacaine/ Clonidine Group | 1.5 |
The investigators hypothesize that patient postoperative anxiety scores are lower in the Ropivacaine/Clonidine group and postoperative anxiety scores decrease more in Ropivacaine /Clonidine Group, than in Ropivacaine Group. (NCT02439281)
Timeframe: 6 hours after block placement
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine Group | 30 |
| Ropivacaine/ Clonidine Group | 29 |
The investigators expect no difference in incidence of complications (e.g. oversedation, hypotension, bradycardia episodes, etc.). (NCT02439281)
Timeframe: until study completion
| Intervention | Participants (Count of Participants) |
|---|---|
| Ropivacaine/ Clonidine Group | 1 |
| Ropivacaine Group | 1 |
The investigators hypothesize that rectus sheath injections with ropivacaine/ clonidine would result in longer duration of analgesia and decreased pain scores compared to ropivacaine alone. (NCT02439281)
Timeframe: indicated by the first request for pain medication at umbilicus site
| Intervention | minutes (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 230 |
| Ropivacaine Group | 240 |
The investigators hypothesize that rectus sheath injections with ropivacaine and clonidine result in longer duration of sensory block (paresthesia) compared to ropivacaine alone. (NCT02439281)
Timeframe: Indicated by return of normal sensation (expected average of 12 hours after block placement).
| Intervention | minutes (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 823.5 |
| Ropivacaine Group | 540 |
Total intravenous morphine equivalents mg/kg (NCT02439281)
Timeframe: 18 hours after surgery
| Intervention | mg/kg (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 0.20 |
| Ropivacaine Group | 0.22 |
The investigators hypothesize that rectus sheath injections with ropivacaine/ clonidine would result in better satisfaction with pain control. (NCT02439281)
Timeframe: Prior to hospital discharge (up to 24 hours after surgery)
| Intervention | units on a scale (Median) |
|---|---|
| Ropivacaine/ Clonidine Group | 9 |
| Ropivacaine Group | 9 |
American Shoulder and Elbow Surgeons (ASES) Shoulder Score for pain and function. Range 0-100. Low score = worse shoulder condition. Function, disability, and pain subscores (all ranges 0-50), and are summed for total ASES score. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | units on a scale (Median) |
|---|---|
| Observational | 54.3 |
| Non-Opioid Intervention | 54.2 |
Morphine milli-equivalents In-hospital post-operative. Continuous scale of MME, no defined better/worse. Measured as number and dose of medications taken. For example, if the patient received an opioid, the drug and dose was recorded and converted to MME. A time frame of when to assess opioid use in-hospital post-operative was not used but was a continuous monitor for rescue opioid from in-hospital post-operative through discharge. (NCT03540030)
Timeframe: In-hospital Stay
| Intervention | Morphine milli-equivalents (Median) |
|---|---|
| Observational | 45.0 |
| Non-Opioid Intervention | 19.0 |
Pain at patient discharge or 24-hours, whichever comes first - measured on a 0 (no pain) -10 (worst possible pain) numeric rating scale (NRS). A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 24 hours
| Intervention | score on a scale (Median) |
|---|---|
| Observational | 3.0 |
| Non-Opioid Intervention | 2.0 |
Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Months
| Intervention | score on a scale (Median) |
|---|---|
| Observational | 6 |
| Non-Opioid Intervention | 6 |
Simple Shoulder Test (SST) activity score. Range 0-12. 0 = worse activity score. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | score on a scale (Median) |
|---|---|
| Observational | 2.0 |
| Non-Opioid Intervention | 2.0 |
post-operative pain: measured on a 0 (no pain) -10 (worst) numeric rating scale (NRS) at 6hrs, 12hrs, 2 weeks, and 2 months. A score of 0(no pain) is preferable to 10(worst possible pain) (NCT03540030)
Timeframe: 6hrs, 12hrs, 2weeks, 2 months
| Intervention | score on a scale (Median) | |||
|---|---|---|---|---|
| 6 Hrs | 12 hrs | 2 weeks | 2 months | |
| Non-Opioid Intervention | 0.0 | 0 | 0.82 | 0 |
| Observational | 2 | 4 | 1.3 | 0.7 |
rate of constipation (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 4 | 27 | 4 |
| Observational | 7 | 21 | 2 |
rate of constipation (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 13 | 22 | 0 |
| Observational | 19 | 9 | 2 |
rate of falls (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 4 | 27 | 4 |
| Observational | 4 | 24 | 2 |
rate of falls (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 5 | 30 | 0 |
| Observational | 1 | 27 | 2 |
rate of nausea (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 1 | 30 | 0 |
| Observational | 0 | 28 | 2 |
rate of nausea (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 1 | 34 | 0 |
| Observational | 5 | 23 | 2 |
Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Months
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 29 | 2 | 4 |
| Observational | 23 | 5 | 2 |
Satisfaction with overall pain using Numeric Pain Rating (NRS) scale. yes, no. No being better than yes. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | Participants (Count of Participants) | ||
|---|---|---|---|
| Yes | No | Unknown | |
| Non-Opioid Intervention | 34 | 1 | 0 |
| Observational | 27 | 1 | 2 |
quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Months
| Intervention | score on a scale (Median) | |
|---|---|---|
| PCS | MCS | |
| Non-Opioid Intervention | 40.3 | 60.8 |
| Observational | 38.4 | 58.7 |
quality of life using VR-12 subscores. Physical Health (PCS) subscore and Mental Health (MCS) subscore, not summed. Range reported in weighted units. Physical Health subscore: 1 point increase in PCS is associated with 6% lower total health care expenditures, 5% lower pharmacy expenditures, 9% lower rate of hospital inpatient visits, 4% lower rate of medical provider visits, 5% lower rate of hospital outpatient visits. Mental Health sub score a 1 point increase in MCS is associated with 7% lower total health care expenditures, 4% lower pharmacy expenditures, 15% lower rate of hospital inpatient visits, and 4% lower rate of medical provider visits. Both PCS/MCS are score 0-100 with 100 indicating the highest level of health. (NCT03540030)
Timeframe: 2 Weeks
| Intervention | score on a scale (Median) | |
|---|---|---|
| PCS | MCS | |
| Non-Opioid Intervention | 35.0 | 59.1 |
| Observational | 36.7 | 56.3 |
Difference in time in the Post Anesthesia Care Unit (PACU) after surgery (NCT03824808)
Timeframe: During hospitalization, approximately 2 hours post-surgery
| Intervention | Minutes (Mean) |
|---|---|
| Treatment Group | 59 |
| Control Group | 122.5 |
"10-cm Visual Analog Scale (VAS), score of 0 no pain to a score of 10 worst pain ever" (NCT03824808)
Timeframe: Through study completion, assessed at 1h, 2h, 4h, 6h, 12h and 24h post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | score on a scale (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Pain 1 hour post operative | Pain 2 hours post operative | Pain 4 hours post operative | Pain 6 hours post operative | Pain 12 hours post operative | Pain 24 hours post operative | Pain 48 hours post operative | Pain 72 hours post operative | Pain 96 hours post operative | Pain 120 hours post operative | Pain on discharge | Pain at post operative visit | |
| Treatment Group | 5.5 | 4.4 | 4.8 | 4.0 | 3.6 | 2.3 | 2.5 | 5 | 6 | 5 | 1 | 0.5 |
"10-cm Visual Analog Scale (VAS), score of 0 no pain to a score of 10 worst pain ever" (NCT03824808)
Timeframe: Through study completion, assessed at 1h, 2h, 4h, 6h, 12h and 24h post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | score on a scale (Mean) | ||||||||
|---|---|---|---|---|---|---|---|---|---|
| Pain 1 hour post operative | Pain 2 hours post operative | Pain 4 hours post operative | Pain 6 hours post operative | Pain 12 hours post operative | Pain 24 hours post operative | Pain 48 hours post operative | Pain on discharge | Pain at post operative visit | |
| Control Group | 4.0 | 4.2 | 3.1 | 2.5 | 2.4 | 1.9 | 2 | 2 | 0.5 |
Difference in opioid consumption in first 24 hours, discharge and 21 days post-operatively (morphine equivalents) (NCT03824808)
Timeframe: Through study completion, assessed for first 24-hours post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | Milligram Morphine Equivalent (Mean) | |||
|---|---|---|---|---|
| Milligram morphine equivalent (MME) 0-24h postop | Milligram morphine equivalent (MME) 25-48h postop | Milligram morphine equivalent (MME) prescribed at discharge for home use | Milligram morphine equivalent (MME) used of discharge prescription | |
| Control Group | 12.0 | 21.3 | 23.0 | 8.8 |
Difference in opioid consumption in first 24 hours, discharge and 21 days post-operatively (morphine equivalents) (NCT03824808)
Timeframe: Through study completion, assessed for first 24-hours post operatively, then every 24 hours until discharge, and at the post operative visit which occurred within 21-days post-operatively.
| Intervention | Milligram Morphine Equivalent (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Milligram morphine equivalent (MME) 0-24h postop | Milligram morphine equivalent (MME) 25-48h postop | Milligram morphine equivalent (MME) 49-72h postop | Milligram morphine equivalent (MME) 73-96h postop | Milligram morphine equivalent (MME) 97-120h postop | Milligram morphine equivalent (MME) prescribed at discharge for home use | Milligram morphine equivalent (MME) used of discharge prescription | |
| Treatment Group | 22.5 | 26.3 | 7.5 | 7.5 | 7.5 | 26.8 | 20.0 |
(NCT01490931)
Timeframe: 2 Hours
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 9.1 |
Pain intensity scores will be recorded by patient employing a standard 100 mm visual analog scale (NCT01490931)
Timeframe: 20 minutes post dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 14.3 |
(NCT01490931)
Timeframe: 3 hours post-dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 9.6 |
(NCT01490931)
Timeframe: 4 Hours post-dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 10.0 |
VAS pain intensity score at 40 minutes post-dose (NCT01490931)
Timeframe: 40 minutes post dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 10.1 |
(NCT01490931)
Timeframe: 5 Hours post-dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 16.2 |
(NCT01490931)
Timeframe: 6 Hours post-dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 19.8 |
VAS pain intensity score 60 minutes after dosing. (NCT01490931)
Timeframe: 60 minutes post dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 10.6 |
(NCT01490931)
Timeframe: 90 minutes post-dose
| Intervention | millimeters (Mean) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 9.6 |
Measure obtained using recognized double-stop watch technique. Patient is asked to depress the second stop watch when pain relief is meaningful to them. Each patient decides what meaningful relief is for them. (NCT01490931)
Timeframe: At time of depressing meaningful relief stopwatch up to 6 hours.
| Intervention | seconds (Median) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 172 |
Self explanatory (NCT01490931)
Timeframe: Up to 5 days
| Intervention | days (Number) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 3 |
(NCT01490931)
Timeframe: Up to 5 hours after last suture is placed
| Intervention | percentage of participants (Number) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 89 |
Data will be obtained employing the well-described double stop watch technique (NCT01490931)
Timeframe: Censored at 6 hours
| Intervention | seconds (Median) |
|---|---|
| Ketorolac Nasal Spray 31.5 mg (SPRIX) | 86 |
"Daily opioid consumption assessed as number of pills taken that day, each day for 7 days post-operatively~Outcome measure reported below is mean number of opioid pills consumed per day." (NCT02313675)
Timeframe: 7 days
| Intervention | pills consumed (Mean) |
|---|---|
| IV Tylenol | 0.2 |
| IV Toradol | 0.7 |
| IV Tylenol/Toradol Combination | 1.0 |
| Saline | 0.7 |
This is an ordinal pain scale. The patient picks a number from 0-10 scale every 4 hours for 7 days post-operatively. 0 is no pain, 10 is the worst pain imaginable. Lower scores would be preferable to higher scores. (NCT02313675)
Timeframe: 7 days
| Intervention | units on a scale (Mean) |
|---|---|
| IV Tylenol | 2.0 |
| IV Toradol | 2.9 |
| IV Tylenol/Toradol Combination | 2.7 |
| Saline | 2.0 |
Pain intensity (PI) is measured using the 11-point (0-10) Numeric Pain Rating Scale (NPRS) score. PID is the arithmetic difference in NPRS score at the time point of interest from the baseline score. SPID48 is the sum of time-weighted PID scores measured 22 times over the 48 hour assessment period, with a total score ranging from -480 (worst) to 480 (best). A higher SPID value indicates greater pain relief. (NCT01484652)
Timeframe: 48 hours
| Intervention | scores on a scale (Mean) |
|---|---|
| COV795 | 114.9 |
| Placebo | 66.9 |
The dosage of the rescue medication (rescue medications are medicines that are administered to the participants when the efficacy of the study drug is not satisfactory, or the effect of the study drug is too great and is likely to cause a hazard to the participant, or to manage an emergency situation) because of insufficient pain relief was measured after administration of the study drug. Rescue medications allowed were oral or injection of tramadol HCl (intramuscular or intravenous injection). (NCT01814878)
Timeframe: Baseline up to Day 3
| Intervention | Milligram (Mean) |
|---|---|
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 50.0 |
| Tramadol HCl/Acetaminophen IR | 51.7 |
The frequency of the rescue medication (rescue medications are medicines that are administered to the participants when the efficacy of the study drug is not satisfactory, or the effect of the study drug is too great and is likely to cause a hazard to the participant, or to manage an emergency situation) because of insufficient pain relief was measured after administration of the study drug. Rescue medications allowed were oral or injection of tramadol HCl (intramuscular or intravenous injection). (NCT01814878)
Timeframe: Baseline up to Day 3
| Intervention | Doses (Mean) |
|---|---|
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 2.1 |
| Tramadol HCl/Acetaminophen IR | 1.4 |
The PGIC was used to assess the degree of participant's overall improvement with treatment, and participants were instructed to assess how much the overall status had been improved after investigational product administration compared to baseline in 7 grades (1=Very much improved and B=Very much worsened). (NCT01814878)
Timeframe: Day 3
| Intervention | Units on scale (Mean) |
|---|---|
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 2.71 |
| Tramadol HCl/Acetaminophen IR | 2.60 |
The SPID is time-weighted sum of all observations of pain intensity difference (PID) collected at each measurement time point from Baseline to 48 hours. PID: Baseline pain intensity (PI) minus current PI; PI was assessed using 11-point numeric rating scale (NRS, 0=no pain to 10=worst pain imaginable). PI score ranges from 0-3 where 0=no pain and 3=severe pain. PI score of 0=NRS score of 0, PI score of 1=NRS score >=1 and <=3, PI score of 2=NRS score of >=4 and <=6 and PI score of 3=NRS score of >=7 and <=10. Total score for SPID at 48 hours (SPID48) ranges from -144 (worst) to 144 (best). (NCT01814878)
Timeframe: Hour 48
| Intervention | Units on scale (Mean) |
|---|---|
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 32.5 |
| Tramadol HCl/Acetaminophen IR | 37.2 |
The time until administration of the first rescue medication (rescue medications are medicines that are administered to the participants when the efficacy of the study drug is not satisfactory, or the effect of the study drug is too great and is likely to cause a hazard to the participant, or to manage an emergency situation) because of insufficient pain relief after administration of the study drug was recorded. Rescue medications allowed were oral or injection of tramadol HCl (intramuscular [directly into muscle] or intravenous injection [directly into vein]). (NCT01814878)
Timeframe: Baseline up to Day 3
| Intervention | Minutes (Mean) |
|---|---|
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 1339 |
| Tramadol HCl/Acetaminophen IR | 1212 |
The SPID is time-weighted sum of all observations of PID collected at each measurement time point from Baseline to 24 hours. PID: Baseline PI minus current PI; PI was assessed using 11-point NRS, 0=no pain to 10=worst pain imaginable. PI score ranges from 0-3 where 0=no pain and 3=severe pain. PI score of 0=NRS score of 0, PI score of 1=NRS score >=1 and <=3, PI score of 2=NRS score of >=4 and <=6 and PI score of 3=NRS score of >=7 and <=10. Total score ranges from -18 (worst) to 18 (best) for SPID6, -36 (worst) to 36 (best) for SPID12 and -72 (worst) to 72 (best) for SPID24. (NCT01814878)
Timeframe: Hour 6, 12, 24
| Intervention | Units on scale (Mean) | ||
|---|---|---|---|
| Hour 6 | Hour 12 | Hour 24 | |
| Tramadol HCl/Acetaminophen IR | 3.9 | 8.1 | 17.6 |
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 3.6 | 7.0 | 14.6 |
The SPRID is sum of SPID and TOTPAR. In SPID, PI score ranges from 0-3 where 0=no pain and 3=severe pain. PI score of 0=NRS score of 0, PI score of 1=NRS score >=1 and <= 3, PI score of 2=NRS score of >=4 and <=6 and PI score of 3=NRS score of >=7 and <=10. In TOTPAR, pain relief score ranges from 0-4 (0=no change, 1=slight relief, 2=moderate relief, 3=fair relief, 4=pain resolved completely). Total score ranges from -18 (worst) to 42 (best) for SPRID6, -36 (worst) to 84 (best) for SPRID12, -72 (worst) to 168 (best) for SPRID24 and -144 (worst) to 336 (best) for SPRID48. (NCT01814878)
Timeframe: Hour 6, 12, 24, 48
| Intervention | Units on scale (Mean) | |||
|---|---|---|---|---|
| Hour 6 | Hour 12 | Hour 24 | Hour 48 | |
| Tramadol HCl/Acetaminophen IR | 10.9 | 23.1 | 49.1 | 97.0 |
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 9.6 | 19.6 | 41.8 | 85.9 |
Pain relief was measured on a 5-point categorical scale of 0-4 (0=no change, 1=slight relief, 2=moderate relief, 3=fair relief, 4=pain resolved completely). TOTPAR was calculated as the time-weighted sum over all pain relief up to 48 hours. Total score ranges from 0 (worst) to 24 (best) for TOTPAR6, 0 (worst) to 48 (best) for TOTPAR12, 0 (worst) to 96 (best) for TOTPAR24 and 0 (worst) to 192 (best) for TOTPAR48. (NCT01814878)
Timeframe: Hour 6, 12, 24, 48
| Intervention | Units on scale (Mean) | |||
|---|---|---|---|---|
| Hour 6 | Hour 12 | Hour 24 | Hour 48 | |
| Tramadol HCl/Acetaminophen IR | 6.8 | 14.7 | 31.0 | 61.7 |
| Tramadol Hydrochloride (HCl)/Acetaminophen ER | 6.0 | 12.5 | 27.1 | 55.6 |
Quality of recovery will be evaluated through the use of the validated Quality of Recovery-40 questionnaire. The hypothesis is that the intravenous acetaminophen group will experience an increased quality of recovery as compared to the placebo group. (NCT02400580)
Timeframe: 4 weeks
| Intervention | units on a scale (Mean) |
|---|---|
| Intravenous IV Acetaminophen | 4.11 |
| Normal Saline | 4.31 |
The secondary outcome is comparison of narcotic pain medical requirements within the first 24 hours after surgery. The hypothesis is that the intravenous acetaminophen group will require less narcotic medications than the placebo group. Narcotic use in this study will be calculated by converting all narcotics (fentanyl, dilaudid etc) into standardized units of morphine using well validated conversion tables. (NCT02400580)
Timeframe: 24 hours
| Intervention | Morphine Equivalents (Mean) |
|---|---|
| Intravenous IV Acetaminophen | 16.4 |
| Normal Saline | 18.4 |
A secondary aim of this study is to compare post-operative nausea on post-operative day zero and one as reported by the patients on a visual analog scale with a range of 0 to 10 where 0 is no nausea at all and 10 is the worst nausea that a person can imagine. Less nausea is considered preferable to more nausea. The hypothesis is that the intravenous acetaminophen group will experience decreased nausea compared with the placebo group. (NCT02400580)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Intravenous IV Acetaminophen | 0.69 |
| Normal Saline | 0.85 |
A secondary aim of this study is to compare post-operative vomiting scores on post-operative day zero and one. Vomiting is reported as either having vomited or not vomited. The hypothesis is that the intravenous acetaminophen group will experience decreased vomiting compared with the placebo group. (NCT02400580)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Intravenous IV Acetaminophen | 1 |
| Normal Saline | 2 |
The primary aim of this study is to compare overall post-surgical pain after hysterectomy as reported by the patients on a visual analog scale with a range of 0 to 10 where 0 is no pain at all and 10 is the worst pain that a person can imagine. Less pain is considered preferable to more pain. The theory is that patients who have intravenous acetaminophen will report less post-surgical pain. (NCT02400580)
Timeframe: 24 hours
| Intervention | units on a visual analog scale (Mean) |
|---|---|
| Intravenous IV Acetaminophen | 3.55 |
| Normal Saline | 3.11 |
Patient perception of satisfaction at time of discharge on post-operative day zero will be evaluated. The hypothesis is that intravenous acetaminophen group will experience increased satisfaction for discharge than the placebo group. (NCT02400580)
Timeframe: 24 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Intravenous IV Acetaminophen | 7.76 |
| Normal Saline | 8.15 |
Determine the impact of administering a supplemental non-opioid analgesic drug such as IV/oral acetaminophen on total opioid dose administered over the perioperative period. (NCT03104816)
Timeframe: Within 24 hours after surgery
| Intervention | mg (Mean) | |
|---|---|---|
| PACU dose | Ward dose | |
| Acetaminophen IV Soln 10 MG/ML (A) | 1.2 | 9.8 |
| Hydromorphone (Control Arm) (C) | 1.7 | 13 |
| PO Acetaminophen (B) | 1.3 | 10.4 |
Feasibility of collecting data on the percentage of patients who develop chronic opioid use. This is measured as the number of patients who received an opioid prescription per the Arkansas prescription drug monitoring database during the 90-150 day period post operatively. (NCT03986866)
Timeframe: 90-150 days
| Intervention | Participants (Count of Participants) |
|---|---|
| No Video | 12 |
| Video | 5 |
Knowledge of Post operative Opioids after surgery via 7 day post operative phone call. Knowledge is measured on a scale of 1 to 10 with 10 being complete knowledge and 1 being no knowledge. (NCT03986866)
Timeframe: 7 days
| Intervention | units on a scale (Mean) |
|---|---|
| No Video | 8.32 |
| Video | 9.36 |
Post-operative pain control as determined by opioid utilization at three months. This is the number of patients that have discontinued opioids at the 3 month mark. (NCT03986866)
Timeframe: Up to 3 months
| Intervention | Participants (Count of Participants) |
|---|---|
| No Video | 47 |
| Video | 38 |
Feasibility of collecting data on the number of days until opioid cessation (NCT03986866)
Timeframe: Up to 3 months
| Intervention | days (Mean) |
|---|---|
| No Video | 13.9 |
| Video | 13.9 |
Amount of intravenous (IV) opioid consumption within 24-hour period (NCT03856788)
Timeframe: 24 Hours postoperative
| Intervention | morphine milligram equivalents (Median) |
|---|---|
| Saline | 44.7 |
| Bupivacaine | 38.7 |
Amount of intravenous opioid consumption during the surgery (NCT03856788)
Timeframe: average 2-3 Hours
| Intervention | morphine milligram equivalents (Median) |
|---|---|
| Saline | 35 |
| Bupivacaine | 32.5 |
Number of participants who answered yes to having presence of nausea after surgery (NCT03856788)
Timeframe: 24 Hours postoperative
| Intervention | Participants (Count of Participants) |
|---|---|
| Saline | 16 |
| Bupivacaine | 14 |
Patients asked for the areas of pain (right upper quadrant (RUQ), left upper quadrant, (LUQ) right lower quadrant (RLQ), or left lower quadrant (LLQ), diffuse and epigastric) after surgery. (NCT03856788)
Timeframe: 24 Hours postoperative
| Intervention | Participants (Count of Participants) | ||||||
|---|---|---|---|---|---|---|---|
| none | diffuse | RUQ | LUQ | RLQ | LLQ | epigastric | |
| Bupivacaine | 7 | 1 | 3 | 2 | 0 | 0 | 6 |
| Saline | 3 | 7 | 3 | 1 | 0 | 0 | 7 |
The incidence of post-operative hemorrhage, defined as post-operative bleeding requiring medical intervention or hospitalization during the 10 day post-operative follow-up period. (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | Participants (Count of Participants) |
|---|---|
| Celecoxib 200 mg Tablets | 0 |
| Placebo With Same Dosing Schedule as the Active Comparator Arm | 0 |
Participant reported acetaminophen use and its equivalent. Medication use was collected from reported participant journals. (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | mg (Mean) | |||
|---|---|---|---|---|
| Day 1 | Average, days 2 to 4 | Average, days 5 to 7 | Average, days 8 to 10 | |
| Celecoxib as Experimerimental Intervention | 2074 | 2245 | 2028 | 1418 |
| Placebo Control, Active Comparator | 3006 | 2934 | 3610 | 2483 |
Activity level, reported by participant utilizing a 10-point ordinal scale (0 = no activity, 10 = return to normal activities). Activity level was measured was collected once daily. (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | Activity score (units on a scale) (Mean) | |||
|---|---|---|---|---|
| Day 1 | Average, days 2 to 4 | Average, days 5 to 7 | Average, days 8 to 10 | |
| Celecoxib as Experimerimental Intervention | 2.8 | 3.1 | 5.4 | 7.4 |
| Placebo Control, Active Comparator | 4.5 | 4.1 | 3.7 | 5.7 |
Pain score as reported by participant, measured on a 10 point scale, where 0 = none and 10 = unbearable, collected once daily. (NCT00583453)
Timeframe: day of procedure through post-operative day 10
| Intervention | pain score (units on a scale) (Mean) | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Maximum pain, day 1 | maximum pain, averaged across days 2 to 4 | maximum pain, averaged across days 5 to 7 | maximum pain, averaged across days 8 to 10 | Average pain, day 1 | Average pain, averaged across days 2 to 4 | Average pain, averaged across days 5 to 7 | Average pain, averaged across days 8 to 10 | Pain with drinking, day 1 | Pain with drinking, averaged across days 2 to 4 | Pain with drinking, averaged across days 5 to 7 | Pain with drinking, averaged across days 8 to 10 | Activity, day 1 | |
| Celecoxib 200 mg Tablets | 5.0 | 5.1 | 4.4 | 3.6 | 6.1 | 6.2 | 6.1 | 4.9 | 5.7 | 5.4 | 4.9 | 3.9 | 2.8 |
| Placebo With Same Dosing Schedule as the Active Comparator Arm | 6.0 | 6.0 | 5.9 | 4.0 | 7.3 | 7.6 | 7.4 | 5.7 | 6.7 | 6.6 | 5.9 | 4.1 | 4.5 |
Participant reported mophine equivalent use (NCT00583453)
Timeframe: From operative day through 10 days post-operative
| Intervention | mg (Mean) | |||
|---|---|---|---|---|
| Day 1 | Average, days 2 to 4 | Average, days 5 to 7 | Average, days 8 to 10 | |
| Celecoxib as Experimerimental Intervention | 28.9 | 30.4 | 27.8 | 13.2 |
| Placebo Control, Active Comparator | 55.0 | 72.4 | 69.7 | 38.3 |
patient satisfaction is measured as minimum to maximum 1-5; the higher the score the better satisfied (very unsatisfied, unsatisfied, neutral, satisfied, very satisfied) (NCT04003987)
Timeframe: 24 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 3.7 |
| TAP Block | 3.6 |
patient satisfaction is measured as minimum to maximum 1-5; the higher the score the better satisfied (very unsatisfied, unsatisfied, neutral, satisfied, very satisfied) (NCT04003987)
Timeframe: 48 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 3.7 |
| TAP Block | 3.7 |
Visual Analogue Scale (VAS) score taken at rest is measured as minimal to maximal; higher values mean worse pain (scale 0-10) (NCT04003987)
Timeframe: 1 hour after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 2.8 |
| TAP Block | 3 |
Visual Analogue Scale (VAS) score taken at rest measured as minimal to maximal; higher values mean worse pain (scale 0-10) (NCT04003987)
Timeframe: 24 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 3 |
| TAP Block | 2.8 |
Visual Analogue Scale (VAS) score taken at rest measured as minimal to maximal; higher values mean worse pain(scale 0-10) (NCT04003987)
Timeframe: 48 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 2.1 |
| TAP Block | 2 |
Visual Analogue Scale (VAS) score taken with movement is measured as minimal to maximal; higher values mean worse pain (scale 0-10) (NCT04003987)
Timeframe: 1 hour after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 3 |
| TAP Block | 3.5 |
Visual Analogue Scale (VAS) score taken with movement measured as minimal to maximal; higher values mean worse pain (scale 0-10) (NCT04003987)
Timeframe: 24 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 4.3 |
| TAP Block | 4.1 |
Visual Analogue Scale (VAS) score taken with movement measured as minimal to maximal; higher values mean worse pain(scale 0-10) (NCT04003987)
Timeframe: 48 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| ESP Block | 3.4 |
| TAP Block | 3.2 |
Readmission to hospital will be noted (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 3 |
| Bupivacaine Hydrochloride | 3 |
Mortality will be noted at specific timepoints (NCT03270514)
Timeframe: From end of surgery assessed up to 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 0 |
| Bupivacaine Hydrochloride | 1 |
Episodes of NIV such as upper airway masks or similar devices will be quantified (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively or until hospital discharge
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 6 |
| Bupivacaine Hydrochloride | 5 |
Patient will give an assessment regarding pain management on a scale of 0 - 10 with 0 indicating the lowest satisfaction with pain management and 10 indicating the highest satisfaction with pain management (NCT03270514)
Timeframe: Given at the time of discharge up to 30 days post-operatively
| Intervention | score on a scale (Median) |
|---|---|
| Exparel Injectable Product | 10 |
| Bupivacaine Hydrochloride | 10 |
The time it takes until patient ambulates will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours or discharge, *assessed up to 120 hours*
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 42 |
| Bupivacaine Hydrochloride | 45 |
The time it takes until the patient is able to/medically cleared to consume food or liquid will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of oral intake up to 72 hours post-operatively or until hospital discharge
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 7 |
| Bupivacaine Hydrochloride | 5.6 |
The time it takes until the patient advances from bedrest to out of bed (OOB) to chair will be measured (NCT03270514)
Timeframe: From time of end of surgery to time of mobilization up to 72 hours post-operatively
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 16 |
| Bupivacaine Hydrochloride | 16 |
Whether a patient experiences at least one episode of nausea and emesis will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 3 |
| Bupivacaine Hydrochloride | 9 |
Instances of re-intubation will be recorded (NCT03270514)
Timeframe: From time of end of surgery to patient discharge up to one week
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 3 |
| Bupivacaine Hydrochloride | 3 |
The time it takes until the patient is extubated post-operatively will be measured (NCT03270514)
Timeframe: From the end of surgery until the patient is extubated up to 72 hours post-operatively
| Intervention | hours (Median) |
|---|---|
| Exparel Injectable Product | 3.85 |
| Bupivacaine Hydrochloride | 3.47 |
Frequency of incentive spirometry will be measured (NCT03270514)
Timeframe: From time of end of surgery to 72 hours post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Exparel Injectable Product | 29 |
| Bupivacaine Hydrochloride | 31 |
Length of both hospital and ICU stay will be measured (NCT03270514)
Timeframe: From date of surgery assessed up to 30 day post-operatively
| Intervention | days (Median) | |
|---|---|---|
| Length of ICU stay | Length of postoperative hospital stay | |
| Bupivacaine Hydrochloride | 1.71 | 6 |
| Exparel Injectable Product | 1.51 | 7 |
Postoperative pain scores evaluated by numeric rating scale or (NRS) where 0- no pain and 10- worst pain, at rest and at movement (NCT03270514)
Timeframe: NRS scores will be evaluated every 4 hours until 24 hours post-operatively, every 8 hours until 48 hours post-operatively, and every 12 hours for 72 hours post-operatively
| Intervention | score on a scale (Mean) | |||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 4hrs. at rest | 4hrs. with movement | 8hrs. at rest | 8hrs. with movement | 12hrs. at rest | 12hrs. with movement | 16hrs. at rest | 16hrs. with movement | 20hrs. at rest | 20hrs. with movement | 24hrs. at rest | 24hrs. with movement | 32hrs. at rest | 32hrs. with movement | 40hrs. at rest | 40hrs. with movement | 48hrs. at rest | 48hrs. with movement | 60hrs. at rest | 60hrs. with movement | 72hrs. at rest | 72hrs. with movement | |
| Bupivacaine Hydrochloride | 5.03 | 6.64 | 4.996 | 6.6 | 4.962 | 6.56 | 4.928 | 6.52 | 4.894 | 6.48 | 4.86 | 6.44 | 4.792 | 6.32 | 4.724 | 6.24 | 4.656 | 6.16 | 4.554 | 6.04 | 4.452 | 5.92 |
| Exparel Injectable Product | 4.7482 | 5.75 | 4.7262 | 5.74 | 4.7042 | 5.73 | 4.6822 | 5.72 | 4.6602 | 5.71 | 4.6382 | 5.7 | 4.5942 | 5.68 | 4.5282 | 5.66 | 4.4622 | 5.64 | 4.3742 | 5.61 | 4.2862 | 5.58 |
Stress response suppression as a result of treatment will be evaluated by comparing hormone levels between the groups. Serum cortisol levels will be taken to measure this. (NCT03270514)
Timeframe: Measured 8, 48, and 72 hours post-operatively
| Intervention | µg/dL (Median) | ||
|---|---|---|---|
| 8 hours postoperatively | 48 hours postoperatively | 72 hours postoperatively | |
| Bupivacaine Hydrochloride | 36.5 | 19 | 17 |
| Exparel Injectable Product | 30 | 15 | 16 |
All narcotics administered in the first 0-8, 8-24, 24-48, and 48-72 hours and the total narcotics administered in the 0-72 hours postoperative period(PCA narcotics, nurse-administered IV narcotics, and oral narcotics). All narcotics will be converted to total IV morphine equivalent for comparison between two groups. (NCT03270514)
Timeframe: 0-72 hours post-operative period
| Intervention | oral morphine equivalents in mg (Median) | ||||
|---|---|---|---|---|---|
| 0-8 hours | 8-24 hours | 24-48 hours | 48-72 hours | 0-72 hours | |
| Bupivacaine Hydrochloride | 10 | 34.5 | 45 | 26.5 | 105 |
| Exparel Injectable Product | 15 | 45 | 45 | 15 | 139 |
milliliters (mL) (NCT04429022)
Timeframe: 0-300 minutes
| Intervention | milliliters (Mean) |
|---|---|
| Prospective Cohort | 63.50 |
| Historical Control | 58.46 |
Length of stay in hours (NCT04429022)
Timeframe: 0- 240 hours
| Intervention | hours (Mean) |
|---|---|
| Prospective Cohort | 12.05 |
| Historical Control | 35.82 |
Number of patients with return to the clinic, emergency department due to post operative pain within a 2 week period (NCT04429022)
Timeframe: 0-14 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Prospective Cohort | 1 |
| Historical Control | 3 |
minutes (NCT04429022)
Timeframe: 0-300 minutes
| Intervention | minutes (Mean) |
|---|---|
| Prospective Cohort | 128.80 |
| Historical Control | 139.69 |
Subjective, Score 0-10 with 0 being no pain and 10 being severe pain (NCT04429022)
Timeframe: 0-3 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Prospective Cohort | 3.82 |
| Historical Control | 5.13 |
Subjective, Score 0-10 with 0 being no pain and 10 being severe pain (NCT04429022)
Timeframe: 3-24 hours after surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Prospective Cohort | 1.75 |
| Historical Control | 5.43 |
Total opioid pain medications required 0-3h post op in morphine milligram equivalents (MME) (NCT04429022)
Timeframe: 0-3 hours after surgery
| Intervention | morphine milligram equivalents (MME) (Mean) |
|---|---|
| Prospective Cohort | 2.00 |
| Historical Control | 5.32 |
Total opioid pain medications required through 3-24h post op in MME (NCT04429022)
Timeframe: 3-24 hours after surgery
| Intervention | morphine milligram equivalents (MME) (Mean) |
|---|---|
| Prospective Cohort | .20 |
| Historical Control | 12.27 |
Average inpatient hydromorphone use measured in milligrams (NCT03331315)
Timeframe: 48 hrs following surgery
| Intervention | Milligrams (Mean) |
|---|---|
| Ketorolac | 0.7 |
| Celecoxib | 0.8 |
Average inpatient ondansetron use measured in milligrams (NCT03331315)
Timeframe: 48 hrs following surgery
| Intervention | Milligrams (Mean) |
|---|---|
| Ketorolac | 1.5 |
| Celecoxib | 1.3 |
Pain measured using the Visual Analog Scale, no pain (0-0.4 cm), mild pain(0.5-4.4 cm), moderate pain (4.5-7.4 cm), and severe pain (7.5-10.0 cm). Subscale scoring was not used in analysis but provided as reference for patient and nursing staff. (NCT03331315)
Timeframe: 48 hrs following surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Ketorolac | 2.7 |
| Celecoxib | 2.4 |
Measured using postoperative questionnaire (NCT03331315)
Timeframe: 2 weeks after discharge
| Intervention | Days (Mean) |
|---|---|
| Ketorolac | 5.7 |
| Celecoxib | 3.8 |
Number of oral narcotic pills used after discharge until 2 week postoperative visit. (NCT03331315)
Timeframe: 2 weeks after discharge
| Intervention | Pills (Mean) |
|---|---|
| Ketorolac | 8.1 |
| Celecoxib | 6.0 |
Perioperative Complications measured intraoperatively and postoperatively by type (NCT03331315)
Timeframe: During and after surgery
| Intervention | Patients (Number) |
|---|---|
| Ketorolac | 5 |
| Celecoxib | 6 |
Average number of days required for complete return to independent activities of daily living (NCT03331315)
Timeframe: 2 weeks after discharge
| Intervention | Days (Mean) |
|---|---|
| Ketorolac | 2.4 |
| Celecoxib | 2.2 |
Total hospital stay from time fo admission to time of discharge measured in hours (NCT03331315)
Timeframe: Following surgery
| Intervention | Hours (Mean) |
|---|---|
| Ketorolac | 11.6 |
| Celecoxib | 11.9 |
Rescue narcotic in both groups will be recorded and compared using a standard equianalgesic oral morphine equivalent (OME) calculation (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | mg (Mean) |
|---|---|
| Opioid-sparing Group | 26.3 |
| Standard Treatment Group | 62.5 |
Comparison of pain scores between two arms using Visual Analog Scale (VAS) for Pain. Units of measure are 0=No Pain, 1=Annoying, 2=Mild Pain, 3=Troublesome, 4=Nagging Pain, Uncomfortable, 5=Distressing, 6=Miserable, 7=Horrible, 8=Intense, Dreadful, 9=Unbearable, 10=Worst Possible Pain. Higher values represent a worse outcome. There are no subscales. (NCT02351700)
Timeframe: mean pain score over 48 hours
| Intervention | 0-10 units on a scale (Mean) |
|---|---|
| Opioid-sparing Group | 1.7 |
| Standard Treatment Group | 2.8 |
Length of hospital stay from time of surgery to time of discharge. (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | hours (Mean) |
|---|---|
| Opioid-sparing Group | 71.3 |
| Standard Treatment Group | 51.7 |
Epistaxis, potentially related to IV ibuprofen, will be compared between two groups (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | participants (Number) |
|---|---|
| Opioid Sparing Group | 0 |
| Standard Treatment Group | 2 |
patients with one or more bowel movement(s) in the first 48 hours after surgery (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | participants (Number) |
|---|---|
| Opioid-sparing Group | 9 |
| Standard Treatment Group | 12 |
Use of antiemetics in first 48 hours after surgery (NCT02351700)
Timeframe: until discharge from hospital, an expected stay of 2 days
| Intervention | dose (Mean) |
|---|---|
| Opioid-sparing Group | 9.8 |
| Standard Treatment Group | 10.1 |
Total morphine consumption in the first 48 hours after the surgery will be calculated from the drug chart and the Patient controlled analgesia(PCA)pump. (NCT01339273)
Timeframe: 48 hours after the operation
| Intervention | mg (Mean) |
|---|---|
| TAP Block | 47.3 |
| Local Anaesthetic Infiltration | 46.7 |
(NCT01339273)
Timeframe: 24 hours
| Intervention | units on a scale (Median) |
|---|---|
| TAP Block | 0 |
| Local Anaesthetic Infiltration | 0 |
0-10 0= no nausea 10=severe nausea (NCT01339273)
Timeframe: 48 hours after the operation
| Intervention | units on a scale (Median) |
|---|---|
| TAP Block | 0 |
| Local Anaesthetic Infiltration | 0 |
Numerical Rating Scores for Pain (0-10) 0= no pain 10= severe pain (NCT01339273)
Timeframe: 48 hours after the operation
| Intervention | units on a scale (Mean) |
|---|---|
| TAP Block | 2 |
| Local Anaesthetic Infiltration | 2 |
Time will be calculated from the nursing notes and patient diary, when the patient had the first bowel motion. (NCT01339273)
Timeframe: After the operation patients will be followed up till they are medically fit to be discharged from the hospital an expected average of 5-7 days.
| Intervention | days (Median) |
|---|---|
| TAP Block | 2.5 |
| Local Anaesthetic Infiltration | 3 |
Time will be calculated from the nursing notes and patient diary, when the patient first passed flatus. (NCT01339273)
Timeframe: After the operation patients will be followed up till they are medically fit to be discharged from the hospital an expected average of 5-7 days.
| Intervention | days (Median) |
|---|---|
| TAP Block | 1 |
| Local Anaesthetic Infiltration | 1 |
(NCT01339273)
Timeframe: days
| Intervention | days (Median) |
|---|---|
| TAP Block | 4.5 |
| Local Anaesthetic Infiltration | 4.5 |
Time will be calculated from the medical notes, when the decision that the patient is medically fit to be discharged was made. (NCT01339273)
Timeframe: After the operation patients will be followed up till they are medically fit to be discharged from the hospital an expected average of 5-7 days.
| Intervention | days (Median) |
|---|---|
| TAP Block | 4.5 |
| Local Anaesthetic Infiltration | 4.5 |
Time will be calculated from the nursing notes and patient diary, when the patient was first mobilised. (NCT01339273)
Timeframe: After the operation patients will be followed up till they are medically fit to be discharged from the hospital an expected average of 5-7 days.
| Intervention | days (Median) |
|---|---|
| TAP Block | 1 |
| Local Anaesthetic Infiltration | 1 |
(NCT01339273)
Timeframe: days
| Intervention | days (Median) |
|---|---|
| TAP Block | 1 |
| Local Anaesthetic Infiltration | 1 |
Time will be calculated from the nursing notes and patient diary, when the patient resumed normal diet. (NCT01339273)
Timeframe: After the operation patients will be followed up till they are medically fit to be discharged from the hospital an expected average of 5-7 days.
| Intervention | days (Median) |
|---|---|
| TAP Block | 2 |
| Local Anaesthetic Infiltration | 2.5 |
Time will be calculated from the nursing notes and patient diary, when the patient had first successful intake of oral fluids. (NCT01339273)
Timeframe: After the operation patients will be followed up till they are medically fit to be discharged from the hospital an expected average of 5-7 days.
| Intervention | days (Median) |
|---|---|
| TAP Block | 1.5 |
| Local Anaesthetic Infiltration | 2 |
(NCT01339273)
Timeframe: 24 hours
| Intervention | mg (Mean) |
|---|---|
| TAP Block | 30.9 |
| Local Anaesthetic Infiltration | 31 |
The Face, Legs, Activity, Cry, Consolability scale or FLACC scale is a measurement used to assess pain for children between the ages of 2 months and 7 years or individuals that are unable to communicate their pain. The scale is scored in a range of 0-10 with 0 representing no pain. 5 pain measurements were performed at 0, 5, 15, 30, and 60 minutes after PACU arrival. This is the number of participants who reached a FLACC score >/= 4 at one or more time points. (NCT01691690)
Timeframe: 0-60 mins post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| IV Acetaminophen | 58 |
| Saline Placebo | 69 |
Mean time to first drug administration among patients requiring opioid analgesia in the PACU. (NCT01691690)
Timeframe: 0-90 minutes post-operatively
| Intervention | minutes (Mean) |
|---|---|
| IV Acetaminophen | 56.80 |
| Saline Placebo Infused Intraoperatively | 60.46 |
Analgesics administered after arrival to the inpatient ward included hydrocodone/acetaminophen, oxycodone, NSAIDS, acetaminophen, and morphine. (NCT01691690)
Timeframe: 8-12 hours post-operatively
| Intervention | Participants (Count of Participants) | ||||
|---|---|---|---|---|---|
| hydrocodone/acetaminophen | oxycodone | NSAIDS | acetaminophen | morphine | |
| IV Acetaminophen | 68 | 31 | 15 | 3 | 1 |
| Saline Placebo Infused Intraoperatively | 57 | 39 | 22 | 2 | 0 |
If there is any episode of bronchospasm or laryngospasm, it will be noted if it occured during emergence and for 6 hours post operatively. Absence of it will be considered as smooth emergence (NCT02964416)
Timeframe: at the time of extubation till 6 hours postoperatively
| Intervention | Number of Patients (Number) |
|---|---|
| Tramadol | 0 |
| Placebo | 0 |
Requirement of analgesia will be recorded at recovery room, 2, 4 and 6 hours postoperatively. If there is any need of analgesic, it will be noted and will be considered as one of the determinants of poor quality of emergence. (NCT02964416)
Timeframe: At Recovery room, 2, 4 and 6 hours postoperatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Recovery Room | 2h | 4h | 6h | |
| Placebo | 3 | 23 | 4 | 7 |
| Tramadol | 5 | 15 | 3 | 6 |
Convulsions will be recorded at Recovery Room, 2, 4 and 6 hours postoperatively.If there is any episode of convulsion, it will be noted. Absence of it will be considered as smooth emergence. (NCT02964416)
Timeframe: at Recovery Room, 2, 4 and 6 hours postoperatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Recovery Room | 2h | 4h | 6h | |
| Placebo | 0 | 0 | 0 | 0 |
| Tramadol | 0 | 0 | 1 | 0 |
"Post operative Glasgow Coma Scale (GCS) will be recorded at Recovery Room, 2, 4 and 6 hours postoperatively. If there is any deterioration in GCS less than 8/15, Patients will be intubated.~GCS categories <8 Low GCS 9-12 Intermediate GCS 13-15 Full GCS" (NCT02964416)
Timeframe: at Recovery Room, 2, 4 and 6 hours postoperatively
| Intervention | Number of Patients (Number) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Recovery Room : <8 | Recovery Room : 9-12 | Recovery Room : 13-15 | 2h : <8 | 2h : 9-12 | 2h : 13-15 | 4h : <8 | 4h : 9-12 | 4h : 13-15 | 6h : <8 | 6h : 9-12 | 6h : 13-15 | |
| Placebo | 0 | 0 | 41 | 0 | 1 | 40 | 1 | 0 | 40 | 1 | 0 | 40 |
| Tramadol | 0 | 1 | 38 | 0 | 1 | 38 | 0 | 0 | 39 | 0 | 0 | 39 |
Post operative nausea vomiting will be recorded at RR, 2, 4 and 6 hours postoperatively. If there is any episode of PONV it will be noted. Absence of it will be considered as smooth emergence (NCT02964416)
Timeframe: at Recovery Room , 2, 4 and 6 hours postoperatively
| Intervention | Participants (Count of Participants) | |||
|---|---|---|---|---|
| Recovery Room | 2h | 4h | 6h | |
| Placebo | 0 | 3 | 1 | 1 |
| Tramadol | 0 | 3 | 0 | 0 |
Diastolic blood pressure will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If values of blood pressure rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: Diastolic BP from the time of extubation till 6 hours post operatively
| Intervention | mm Hg (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Base line | 1min Before Extubation | 1min After Extubation | 2 min | 5min | 10min | 20min | 30min | 1h | 2h | 4h | 6h | |
| Placebo | 77.83 | 78.65 | 85.78 | 82.41 | 78.59 | 78.32 | 76.73 | 76.93 | 75.33 | 75.89 | 78.00 | 74.89 |
| Tramadol | 75.92 | 77.30 | 83.97 | 79.19 | 78.68 | 77.37 | 78.19 | 77.14 | 76.39 | 75.71 | 74.85 | 75.26 |
Heart rate will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If haemodynamic values of heart rate rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: HR from the time of extubation till 6 hours post operatively
| Intervention | bpm (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 1min Before Extubation | 1min After Extubation | 2 min | 5min | 10min | 20min | 30min | 1h | 2h | 4h | 6h | |
| Placebo | 79.37 | 91.41 | 98.54 | 93.50 | 90.00 | 86.70 | 83.38 | 84.10 | 82.46 | 81.97 | 81.23 | 78.20 |
| Tramadol | 82.26 | 89.30 | 93.61 | 89.61 | 86.27 | 86.26 | 82.44 | 81.92 | 79.53 | 80.03 | 78.94 | 79.65 |
Systolic blood pressure will be recorded at 1 minute before giving the reversal (glycopyrolate and neostigmine) and then 1,2,5,10,20,30 minutes ,1,2,4 and 6 hours after extubation. If values of blood pressure rise more than 20% from baseline values injection Metoprolol 1mg (beta blocker) bolus will be used and titrated according to response. The study will end at 6 hours post extubation. (NCT02964416)
Timeframe: Systolic BP from the time of extubation till 6 hours post operatively
| Intervention | mm Hg (Mean) | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Baseline | 1min Before Extubation | 1min After Extubation | 2 min | 5min | 10min | 20min | 30min | 1h | 2h | 4h | 6h | |
| Placebo | 132.34 | 134.29 | 143.70 | 139.77 | 133.37 | 131.59 | 133.15 | 132.10 | 129.80 | 125.74 | 125.81 | 122.61 |
| Tramadol | 128.55 | 132.63 | 141.81 | 134.89 | 130.05 | 126.95 | 127.86 | 127.19 | 128.11 | 127.76 | 127.35 | 122.97 |
"If there is any episodes of denaturation (Oxygen saturation <92%), it will be noted it it is occurring during emergence.~Absence of it will be considered as smooth emergence" (NCT02964416)
Timeframe: at the time of extubation
| Intervention | Participants (Count of Participants) | ||||
|---|---|---|---|---|---|
| at resumption of spontaneous breathing | at the time of obeying of verbal commands | at the time of cuff deflation | at the time of extubation | 2 min after extubation | |
| Placebo | 0 | 0 | 0 | 0 | 0 |
| Tramadol | 0 | 0 | 0 | 0 | 0 |
"Cough will be described on following scale 5 = No coughing or straining, 4 = Very smooth minimal coughing, 3 = Moderate coughing, 2 = Marked coughing or straining,~1 = Poor extubation~Cough will be recorded on the above mentioned scale by resident/consultant at following time intervals of emergence~At resumption of spontaneous breathing,~Ability to respond to verbal commands~At cuff deflation~At extubation~2 minutes after extubation. It will be noted if it occurs during emergence at the above mentioned time intervals. Absence of it will be considered as smooth emergence." (NCT02964416)
Timeframe: Cough at the time of emergence
| Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| At resumption of spontaneous breathing72201515 | At resumption of spontaneous breathing72201516 | Ability to respond to verbal commands72201516 | Ability to respond to verbal commands72201515 | At cuff deflation72201516 | At cuff deflation72201515 | At extubation72201516 | At extubation72201515 | 2 minutes after extubation72201515 | 2 minutes after extubation72201516 | |||||||||||||||||||||||||||||||||||||||||
| Poor extubation | Marked coughing or straining | Moderate coughing | Very smooth minimal coughing | No coughing or straining | ||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 33 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 36 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 3 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 34 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 37 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 3 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 4 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 33 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 4 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 6 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 32 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Placebo | 32 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||
| Tramadol | 36 | |||||||||||||||||||||||||||||||||||||||||||||||||
Pain intensity scores were measured using an 11-point numerical pain rating scale (NPRS) with 0=no pain to 10=worst possible pain (NCT00366444)
Timeframe: Over 48 hours after bunionectomy
| Intervention | units on a scale (Mean) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 2.5 |
| Placebo | 5.6 |
(NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | minutes (Median) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 70.2 |
(NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | minutes (Median) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 26.0 |
| Placebo | 22.2 |
(NCT00366444)
Timeframe: Day 1
| Intervention | participants (Number) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 40 |
| Placebo | 87 |
(NCT00366444)
Timeframe: Day 2
| Intervention | participants (Number) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 22 |
| Placebo | 64 |
Day 3 data reflect the use of rescue medication only up to the time of discharge (NCT00366444)
Timeframe: Day 3
| Intervention | participants (Number) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 5 |
| Placebo | 29 |
(NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | participants (Number) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 62 |
| Placebo | 40 |
Times to onset of Perceptible and Meaningful Relief were determined using the double-stopwatch method. (NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | participants (Number) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 58 |
| Placebo | 35 |
Times to onset of Perceptible and Meaningful Relief were determined using the double-stopwatch method. (NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | participants (Number) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 84 |
| Placebo | 69 |
(NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | minutes (Median) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 60 |
Pain relief was rated using a 5-point categorial scale (0=none, 1=a little, 2=some, 3=a lot, and 4=complete) at time of dose (time=0) and over 15 time points afterwards (10, 15, 20, 30, 45, and 60 minutes and at 1.5, 2, 2.5, 3, 4, 5, 6, 7, and 8 hours after the initial dose on Day 1 or until time of re-medication). A score of 0 across all time points would be the lowest (worst) and a score of 60 (4 X 15 time points) would be the highest (best) possible score. (NCT00366444)
Timeframe: 8 hours post single dose
| Intervention | units on a scale (Mean) |
|---|---|
| Zipsor (Diclofenac Potassium) Liquid Filled Capsule | 8.2 |
| Placebo | 2.6 |
"Pain Intensity (PI) as measured by a 100 millimeter (mm) long Visual Analogue Scale (VAS) over 24 hours after treatment minus the Baseline VAS score. The 100 mm VAS was drawn on a pain ruler and labeled at its left end with '0 = No Pain' and with 100 = Worst Pain Imaginable' at its right end. Subjects placed a mark on the scale to represent their perceived pain. The score was the distance in mm from the left end of the VAS to the point where the subject's mark crossed the line. PI at baseline was compared to the PI at each timepoint and differences were summed over the 24 hour time period." (NCT00564486)
Timeframe: Baseline to 24 hrs
| Intervention | Units on a scale (Mean) |
|---|---|
| IV Placebo | -45.2 |
| IV Acetaminophen 1 gm | -194.1 |
"Sum of Pain Intensity (PI) as measured by the 100 mm long Visual Analogue Scale (VAS) over 24 hours after treatment subtracting the Baseline VAS score.The 100 mm VAS was drawn on a pain ruler and labeled at it's left end with 0 = No Pain' and its right end with '100 = Worst Pain Imaginable.' Subjects placed a mark on the scale to represent their perceived pain. The score was the distance in mm from the left end of the VAS to the point where the subject's mark crossed the line. PI difference from baseline was calculated at each assessment over a 24 hour period." (NCT00564486)
Timeframe: Baseline to 24 hrs
| Intervention | Units on a scale (Mean) |
|---|---|
| IV Placebo | -45.2 |
| IV Acetaminophen 650 mg | -323.1 |
"Number of subjects who experienced at least one treatment emergent adverse event (TEAE).~A TEAE is an adverse event that occurs on or after the first dose of study medication (T0)." (NCT00564486)
Timeframe: First dose through 7 day follow up
| Intervention | Subjects (Number) |
|---|---|
| IV Placebo | 68 |
| IV Acetaminophen 1000 mg | 65 |
| IV Acetaminophen 650 mg | 28 |
"The number of subjects who reported at least one treatment emergent SAE during the study.~A Serious Adverse Event is defined as any untoward medical occurrence at any dose of blinded study medication that:~results in death~is life-threatening~requires inpatient hospitalization or causes prolongation of existing hospitalization~results in persistent or significant disability/incapacity~is a congenital anomaly/birth defect~is an important medical event" (NCT00564486)
Timeframe: First dose to 30 days after last dose of study medication.
| Intervention | Subjects (Number) |
|---|---|
| IV Placebo | 2 |
| IV Acetaminophen 1 gm | 1 |
| IV Acetaminophen 650 mg | 3 |
Postoperative opioid consumption over 24 hours. Converted into oral mg of morpine equivalents. (NCT01852955)
Timeframe: 24 hour
| Intervention | oral mg of morpine equivalents (Median) |
|---|---|
| IV Acetaminophen | 20 |
| Placebo | 30 |
Postoperative pain within the post anesthesia care unit after surgery. Area under the numeric rating scale for pain versus time curve in the post anesthesia care unit (score * min).Numeric rating scale for pain on a scale of 0-10 (0 is no pain and 10 is high pain) versus time curve in the post anesthesia care unit ( score * min). Area under a curve units of the horizontal axis multiplied by the units of the vertical axis. A higher value indicates more pain and time in the Post Anesthesia Care Unit.The range is 0 pain to x time in minutes x 1 hour to 5 hour ( 60-300 minutes) . The pain scores were collected at 15 minute intervals from the time of admission to the PACU. The area under the NRS pain scale versus time curve was calculated using the trapezoidal method as an indicator of pain burden during early recovery (Graph Pad Prism ver 5.03, Graph Pad Software INC. (NCT01852955)
Timeframe: Time in the post anesthesia care unit after surgery (average of 5 hours)
| Intervention | (units on a scale * minutes (Median) |
|---|---|
| IV Acetaminophen | 255 |
| Placebo | 240 |
Quality of recovery score 24 hours after the surgical procedure. Total score range of 40 (poor recovery) and a score of 200 (good recovery). (NCT01852955)
Timeframe: 24 hours after the surgical procedure
| Intervention | units on a scale (Median) |
|---|---|
| IV Acetaminophen | 189 |
| Placebo | 183 |
"pain measurement as assessed on a visual analog scale and pain medication usage~definition of success = no or mild pain as analyzed on VAS scale and no narcotic use; analyzed by logistic regression~VAS scale is 0 to 170 mm with the higher numbers indicating more pain and less success." (NCT01870973)
Timeframe: each day for 5 days
| Intervention | percentage of participants (Number) |
|---|---|
| Root Canal Treatment | 52 |
| no Root Canal Treatment | 43 |
"Subjects asked to fill out a patient diary recording their pain intensity level (on 100mm Visual Analog Scale) prior to taking study medication every 4 hours.~The daily average pain intensity levels are reported as a score on a scale of 0-100, with higher score meaning worse outcome.~The daily average pain levels were assessed daily for 1 week post-operatively, then compared between the 2 groups using a two-group Student's t-test." (NCT02029235)
Timeframe: 1 week post-operatively
| Intervention | score on a scale (0-100, higher = worse) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain intensity level on PostOp Day 1 | Daily average pain intensity level on PostOp Day 2 | Daily average pain intensity level on PostOp Day 3 | Daily average pain intensity levelon PostOp Day 4 | Daily average pain intensity level on PostOp Day 5 | Daily average pain intensity level on PostOp Day 6 | Daily average pain intensity level on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 24.07 | 30.16 | 22.11 | 18.53 | 16.61 | 13.58 | 13.00 |
| Acetaminophen/Ibuprofen (AIBU) Group | 22.17 | 22.22 | 15.67 | 13.17 | 14.03 | 13.44 | 12.67 |
"Subjects asked to fill out a patient diary recording their pain relief (on a Likert scale) one hour after taking study medication every 4 hours.~Daily average pain relief scores are reported as a score on a scale of 0-3, with higher score meaning better outcome.~The daily average pain relief scores were assessed daily for 1 week post-operatively, then compared using generalized linear mixed-effects models" (NCT02029235)
Timeframe: 1 week postoperatively
| Intervention | score on a scale (0-3, higher = better) (Mean) | ||||||
|---|---|---|---|---|---|---|---|
| Daily average pain relief on PostOp Day 1 | Daily average pain relief on PostOp Day 2 | Daily average pain relief on PostOp Day 3 | Daily average pain relief on PostOp Day 4 | Daily average pain relief on PostOp Day 5 | Daily average pain relief on PostOp Day 6 | Daily average pain relief on PostOp Day 7 | |
| Acetaminophen/Hydrocodone (AH) Group | 1.53 | 1.76 | 2.33 | 2.46 | 2.54 | 2.84 | 2.88 |
| Acetaminophen/Ibuprofen (AIBU) Group | 1.84 | 2.27 | 2.63 | 2.91 | 2.88 | 2.87 | 2.96 |
Discharge readiness is the number of hours until meeting the following 4 criteria: (1) adequate analgesia (defined as pain less than 4 on a NRS of 0-10); (2) independence from intravenous analgesics; (3) ability to ambulate 30 m and (4) ability to stand, walk 3 m, and return to a sitting position without another's assistance. (NCT01759277)
Timeframe: 7 postoperative days
| Intervention | hours (Median) |
|---|---|
| Control | 61 |
| Experimental | 55 |
The time in hours until adequate analgesia is defined as pain less than 4 on a Numeric Rating Scale of 0-10, with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: First 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 61.6 |
| Experimental | 61.0 |
The time in hours until a patient could ambulate at least 30 meters independently (regardless of time to achieve the 30 meters) (NCT01759277)
Timeframe: 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 40.9 |
| Experimental | 56.6 |
The time in hours until no intravenous analgesics were required for at least 12 hours (without future intravenous use during admission) (NCT01759277)
Timeframe: First 7 postoperative days
| Intervention | Hours (Mean) |
|---|---|
| Control | 46.1 |
| Experimental | 47.5 |
The timed-up-and-go (TUG) test measures the ability and speed of standing from a sitting position, walking 3 meters and returning to the original seated position independent from the assistance of healthcare personnel. This variable measured the time in hours until the patient could successfully achieve this test independently, regardless of the amount of time required. (NCT01759277)
Timeframe: Hours
| Intervention | Hours (Mean) |
|---|---|
| Control | 33.4 |
| Experimental | 46.8 |
Amount of opioid consumed as measured with intravenous morphine equivalents in milligrams (NCT01759277)
Timeframe: Postoperative Days 0-3
| Intervention | milligrams (Mean) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Recovery Room | Postoperative Day 0 (day) | Postoperative Day 0 (evening) | Postoperative Day 1 (night) | Postoperative Day 1 (Day) | Postoperative Day 1 (evening) | Postoperative Day 2 (night) | Postoperative Day 2 (day) | Postoperative Day 2 (evening) | Postoperative Day 3 (night | |
| Control | 8.6 | 0.9 | 7.2 | 5.1 | 11.0 | 8.6 | 4.1 | 9.6 | 6.5 | 4.9 |
| Experimental | 8.0 | 1.5 | 8.5 | 5.6 | 12.6 | 10.9 | 5.6 | 10.2 | 7.2 | 5.1 |
The amount of pain evaluated using the 0-10 Numeric Rating Scale with 0=no pain and 10=worst imaginable pain (NCT01759277)
Timeframe: Postoperative Days 1-3
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| Postoperative Day 1 (08:00-16:00) | Postoperative Day 2 (08:00-16:00) | Postoperative Day 3 (00:00-8:00) | |
| Control | 4.4 | 3.7 | 2.5 |
| Experimental | 3.7 | 3.4 | 2.8 |
The distribution of cutaneous sensation affected by the different techniques of adductor canal blockade is assessed using a monofilament Neuropen to prick points on a 20 point grid applied to the skin in a standard fashion according to this method: A grid will be marked starting with anatomical landmarks at the knee joint: the medial inter-knee-joint point where the tibia meets the femur, the mid medial patella, the mid lateral patella, and along the same line at the semitendinosus tendon and 5cm posterior from that point. Then 5cm intervals will be plotted progressing cephalad to a total of 15 centimeters. This will yield 20 grid points (5x4 points). Once the grid is made, testing proceeds with a Neuropen on a scale of 0-1, with 1 = normal sharp sensation, 0 = change of sensation. The Neuropen is used for the standardization of force. (NCT02788019)
Timeframe: 20 minutes
| Intervention | points of cutaneous sensation (Mean) |
|---|---|
| Mid-Thigh Adductor Block | 19.81 |
| Distal-Thigh Adductor Block | 20 |
Measuring the quadriceps muscle strength (surgical side) using a dynamometer.Patients were placed supine with a cushion underneath their knee, resulting in a 45-degree angle at the knee. A dynamometer was placed on the anterior of the ankle, between the malleoli. Patients were instructed to extend their legs three times each, with a 30-s pause between each attempt (Lafayette Manual Muscle Test System; Lafayette Instrument Company, Lafayette, IN; and all three dynamometer readings in Kgf unit for each leg were recorded.Kgf is a gravitational metric unit force ,it is equal to the magnitude of the force exerted on one kilogram of mass under standard gravity. (NCT03053401)
Timeframe: 4 hours following peripheral nerve block performance
| Intervention | Kilogram-force (Kgf) (Median) |
|---|---|
| Adductor Canal Block | 1.1 |
| Femoral Nerve Block | 0.0 |
Total intravenous morphine/morphine equivalent consumption in milligrams (mg) at 24 hours post-block (NCT03053401)
Timeframe: 24 hours following peripheral nerve block performance.
| Intervention | milligrams (Mean) |
|---|---|
| Adductor Canal Block | 28.9 |
| Femoral Nerve Block | 26.9 |
Assessed by Numeric Scale (NS) pain scoring system. Minimum 0 and maximum 10 . Higher scores means worse outcome (pain) (NCT03053401)
Timeframe: 4 hours and 24 hours
| Intervention | score on a scale (Median) | |
|---|---|---|
| 4 hours post block | 24 hours post block | |
| Adductor Canal Block | 4.5 | 5.0 |
| Femoral Nerve Block | 4.5 | 6.0 |
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Days (Mean) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 2.42 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 2.67 |
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 0 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 0 |
(NCT02121392)
Timeframe: within first 3 days (plus or minus 3 days) after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 0 |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 0 |
(NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter
| Intervention | milligrams of morphine (Mean) | |
|---|---|---|
| 12 hours postoperatively | 20 hours after placement of catheter | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 12.5 | 73.9 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 11.9 | 96.5 |
(NCT02121392)
Timeframe: Daily on postoperative days one and two
| Intervention | meters (Mean) | |
|---|---|---|
| Postoperative Day 1 | Postoperative Day 2 | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 17.6 | 39.4 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 13.8 | 32.5 |
Knee range of motion (ROM) was measured (in degrees) during physical therapy. (NCT02121392)
Timeframe: postoperative day 1 and 2
| Intervention | degrees (Mean) | |
|---|---|---|
| Postoperative Day 1 | Postoperative Day 2 | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 40.6 | 62.5 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 51.4 | 71.3 |
(NCT02121392)
Timeframe: 3 and 6 weeks
| Intervention | degrees (Mean) | |
|---|---|---|
| 3 weeks | 6 weeks | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 94.3 | 105 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 98.2 | 109 |
"The visual analog scale (VAS) is a pain rating scale. Scores are based on self-reported measures of symptoms that are recorded with a single mark placed at one point along the length of a line that represents a continuum between the two ends of the scale-no pain on the left end of the scale (equal to a score of 0) and the worst pain on the right end of the scale (equal to a score of 100)." (NCT02121392)
Timeframe: 12 hours postoperatively and 20 hours after placement of catheter
| Intervention | mm (Mean) | |
|---|---|---|
| 12 hours postoperatively | 20 hours after placement of catheter | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 26.9 | 28.6 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 27.9 | 36.4 |
The Western Ontario and McMaster Universities Arthritis Index (WOMAC) is widely used in the evaluation of Hip and Knee Osteoarthritis. It is a self administered questionnaire consisting of 24 items divided into 3 subscales: pain (5 items), stiffness (2 items), and physical function (17 items). The subscale scores can vary, with pain ranging from 0 to 20 points; stiffness, 0 to 8 points; and physical function, 0 to 68 points. Higher scores represent worse pain, stiffness, and functional limitations. A sum of the scores for all three subscales yields a total WOMAC score. (NCT02121392)
Timeframe: 3 and 6 weeks
| Intervention | score on a scale (Mean) | |
|---|---|---|
| 3 weeks | 6 weeks | |
| Epidural Catheter With Adductor Canal Nerve Block Catheter | 29.1 | 27.9 |
| Epidural Catheter Without Adductor Canal Nerve Block Catheter | 37.8 | 32.9 |
Nausea scores will be collected by a study team member post operatively up to 3 days per protocol. Nausea will be recorded as 0=none, 1=mild, 2=moderate, or 3=severe (NCT03151434)
Timeframe: Nausea scores will be documented at 1 hour post op, 24,48,and 72 hours after the surgery.The scores will then be averaged.
| Intervention | units on a scale (Mean) |
|---|---|
| Group #1 | 0.27 |
| Group #2 | 0.27 |
| Group #3 | 0.29 |
Sedation scores will be documented by a study team member post operatively up to 3 days per protocol requirements. Determining if patient is 0=awake and alert, 1=quietly awake, 2=asleep and arousable, or 3=deep sleep. (NCT03151434)
Timeframe: Sedation scores will be documented at 1 hour post op, 24,48,and 72 hours after the sugery. The scores will then be averaged.
| Intervention | units on a scale (Mean) |
|---|---|
| Group #1 | 0.38 |
| Group #2 | 0.32 |
| Group #3 | 0.22 |
Opioid consumption will be collected by a study team member post operatively up to 3 days per protocol time requirements (NCT03151434)
Timeframe: Opioid consumption will be measured at 1 hour post op, 24,48, and 72 hours post op. The total amount will be recorded.
| Intervention | miligram morphine equivalent (Median) |
|---|---|
| Group #1 | 57 |
| Group #2 | 35 |
| Group #3 | 21.3 |
Subjects will be followed up at 24 hours post operatively by a study team member to document patient overall satisfaction scores. Score was recorded as 0=dissatisfied, 1=satisfied, 2=very satisfied. (NCT03151434)
Timeframe: post operatively at hour 24
| Intervention | units on a scale (Mean) |
|---|---|
| Group #1 | 0.89 |
| Group #2 | 0.95 |
| Group #3 | 1.33 |
Subjects will be followed up at 48 hours post operatively by a study team member to document patient overall satisfaction scores. Scores will be recorded as 0=dissatisfied, 1=satisfied, 2=very satisfied. (NCT03151434)
Timeframe: post operatively at hour 48
| Intervention | units on a scale (Mean) |
|---|---|
| Group #1 | 1.19 |
| Group #2 | 1.05 |
| Group #3 | 1.32 |
"The VAS score will be taken with both rest and movement (knee flexion) and will be measured by a study team investigator using Visual Analog Scale (VAS). Using units on a scale of 1-10 for documentation with 10 being the worst pain and 0 being no pain" (NCT03151434)
Timeframe: Pain scores will be measured 24 hours after surgery.
| Intervention | units on a scale (Median) |
|---|---|
| US Guided Single Shot Paravertebral Block | 4.0 |
| US Guided Paravertebral Catheter | 4.5 |
| Thoracic Epidural | 3.0 |
"The VAS scores will be taken with both rest and movement (knee flexion) and will be measured by a study team investigator using Visual Analog Scale (VAS). Usingunits on a scale scale of 1-10 for documentation with 10 being the worst pain and 0 being no pain" (NCT03151434)
Timeframe: Pain scores will be measured 48 hours after surgery.
| Intervention | units on a scale (Median) |
|---|---|
| US Guided Single Shot Paravertebral Block | 3.0 |
| US Guided Paravertebral Catheter | 4.0 |
| Thoracic Epidural | 2.0 |
To assess need for additional intraoperative and/or postoperative pain medication (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydrocodone/Acetaminophen | 0 |
| Placebo | 0 |
To determine whether HC/APAP, given in addition to a standard regimen of ibuprofen, lorazepam, and PCB, affects patient pain perception at the time of uterine aspiration, as measured by distance (mm) from the left of the 100 mm visual analog scale (VAS). The number 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: At time of uterine aspiration (baseline)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 65.7 |
| Placebo | 63.1 |
Distance (mm) from the left of the 100 mm VAS scale (VAS anchors: 0 = none, 100 mm = worst imaginable) recorded after cervical dilation (NCT01330459)
Timeframe: During procedure (approximately 45-90 min after hydrocodone/acetaminophen or placebo, and within 5 minutes of procedure starting)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 47.2 |
| Placebo | 43.9 |
To assess whether HC/APAP is associated with nausea, measured on the 100 mm VAS, recorded 30 minutes postoperatively. VAS anchors: 0 indicates no pain, and 100 indicates worst pain imaginable. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 19.4 |
| Placebo | 11.4 |
Distance (mm) from the left of the 100 mm VAS (VAS anchors: 0 = unsatisfied, 100 mm = very satisfied) recorded 30 minutes after completion of the procedure. (NCT01330459)
Timeframe: 30 minutes after completion of the procedure (which started 45-90 minutes after study drug administration)
| Intervention | mm (Mean) |
|---|---|
| Hydrocodone/Acetaminophen | 74.8 |
| Placebo | 67.3 |
Measure effectiveness of placebo as an adjunct to ibuprofen and paracervical block for pain control during uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive placebo adhesives and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). (NCT03391986)
Timeframe: prior to the procedure (baseline), at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Placebo Adhesives | 70.0 |
| Routine Care | 71.0 |
Using a satisfaction survey (investigator-developed, 6 questions, each question is graded on a scale of 1-5, 1 being very poor and 5 being very good) to measure effectiveness of auricular acupuncture for improving satisfaction. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 5-10 minutes)
| Intervention | percentage of participants (Number) |
|---|---|
| Pyonex Needles | 94 |
| Routine Care | 76 |
Measure effectiveness of auricular acupuncture as an adjunct to ibuprofen and paracervical block for pain control during first trimester uterine aspiration by comparing the maximum pain score; as measured by VAS between women randomized to receive auricular acupuncture and routine care controls - using a 100 mm visual analog scale (VAS-P) (anchors: 0 mm = no pain, 100 mm = worst pain in my life). The VAS has no sub-scales. (NCT03391986)
Timeframe: at the completion of the procedure (approximately 10 minutes later)
| Intervention | score on a scale (Mean) |
|---|---|
| Pyonex Needles | 39.5 |
| Routine Care | 71.0 |
Minutes until rescue medication was given. (NCT01115673)
Timeframe: within 6 Hours
| Intervention | Minutes (Median) |
|---|---|
| ACE-1000 | NA |
| ACE-650 | NA |
| ACE-0 | 99.5 |
Weighted Sum of Pain Intensity Difference and Pain Relief Scores Over Six Hours (SPRID6) - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief. For SPRID6, the total possible minimum value is -300 (worst) and the total possible maximum value is 1200 (best). The weights used in the calculation of weighted sums were equal to the elapsed time (hour) between the time point of interest and the preceding time point. (NCT01115673)
Timeframe: 6 Hours
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 529.4 |
| ACE-650 | 427.3 |
| ACE-0 | 60.0 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 120 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 44.8 |
| ACE-650 | 35.7 |
| ACE-0 | -2.7 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 15 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 5.6 |
| ACE-650 | 6.9 |
| ACE-0 | 1.3 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 180 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 40.8 |
| ACE-650 | 31.9 |
| ACE-0 | -2.6 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 240 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 40.8 |
| ACE-650 | 30.3 |
| ACE-0 | -1.1 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 30 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 21.3 |
| ACE-650 | 21.5 |
| ACE-0 | 0.5 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 300 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 37.9 |
| ACE-650 | 27.1 |
| ACE-0 | -0.1 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 360 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 33.4 |
| ACE-650 | 23.8 |
| ACE-0 | 1.0 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 45 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 33.9 |
| ACE-650 | 32.8 |
| ACE-0 | 0.2 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 60 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 40.4 |
| ACE-650 | 36.6 |
| ACE-0 | -0.1 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time Point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 75 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 43.1 |
| ACE-650 | 37.6 |
| ACE-0 | -0.9 |
Pain Intensity Difference (PID) from Baseline at Each Assessment Time point - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain with a highest possible score of 100. The pain intensity difference was calculated at each time point as the pain intensity score at baseline minus the pain intensity score at the stated time point. (NCT01115673)
Timeframe: 90 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 44.4 |
| ACE-650 | 38.0 |
| ACE-0 | -0.6 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 120 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 60.3 |
| ACE-650 | 50.8 |
| ACE-0 | 8.0 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 15 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 8.3 |
| ACE-650 | 9.4 |
| ACE-0 | 3.0 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 180 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 56.3 |
| ACE-650 | 46.3 |
| ACE-0 | 9.5 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 240 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 56.2 |
| ACE-650 | 44.3 |
| ACE-0 | 12.3 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 30 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 29.6 |
| ACE-650 | 29.9 |
| ACE-0 | 4.8 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 300 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 52.2 |
| ACE-650 | 40.5 |
| ACE-0 | 13.8 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 360 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 48.0 |
| ACE-650 | 36.6 |
| ACE-0 | 14.0 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 45 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 46.1 |
| ACE-650 | 44.8 |
| ACE-0 | 7.9 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 60 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 54.4 |
| ACE-650 | 50.1 |
| ACE-0 | 8.3 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 75 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 58.0 |
| ACE-650 | 52.0 |
| ACE-0 | 8.4 |
Pain Relief Scores at each Assessment Timepoint - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 100 (NCT01115673)
Timeframe: 90 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 59.9 |
| ACE-650 | 53.1 |
| ACE-0 | 10.1 |
Patient Assessment of the Pain Medication - Number of Subjects rating the medication they received as a pain reliever on a score of 0-4, where 0=poor, 1=fair, 2=good, 3=very good, 4=excellent (NCT01115673)
Timeframe: 6 Hours
| Intervention | Units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 2.28 |
| ACE-650 | 1.95 |
| ACE-0 | 0.60 |
Percentage of Subjects with >50% of the Maximum Possible TOTPAR6 Score - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief with a highest possible score of 600 so >50% is >300 out of 600 (NCT01115673)
Timeframe: 6 Hours
| Intervention | Percentage of Participants (Number) |
|---|---|
| ACE-1000 | 56.9 |
| ACE-650 | 44.4 |
| ACE-0 | 6.7 |
Percentage of subjects using rescue medication. (NCT01115673)
Timeframe: through 4 Hours
| Intervention | Percentage of Participants (Number) |
|---|---|
| ACE-1000 | 20.1 |
| ACE-650 | 32.4 |
| ACE-0 | 80.0 |
Percentage of subjects using rescue medication. (NCT01115673)
Timeframe: through 6 Hours
| Intervention | Percentage of Participants (Number) |
|---|---|
| ACE-1000 | 29.3 |
| ACE-650 | 45.6 |
| ACE-0 | 80.0 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 120 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 105.1 |
| ACE-650 | 86.5 |
| ACE-0 | 5.3 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 15 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 13.9 |
| ACE-650 | 16.4 |
| ACE-0 | 4.2 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 180 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 97.1 |
| ACE-650 | 78.2 |
| ACE-0 | 6.9 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 240 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 97.0 |
| ACE-650 | 74.6 |
| ACE-0 | 11.2 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 30 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 50.9 |
| ACE-650 | 51.3 |
| ACE-0 | 5.2 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 300 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 90.1 |
| ACE-650 | 67.6 |
| ACE-0 | 13.7 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 360 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 81.4 |
| ACE-650 | 60.4 |
| ACE-0 | 15.0 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 45 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 80.0 |
| ACE-650 | 77.6 |
| ACE-0 | 8.1 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 60 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 94.9 |
| ACE-650 | 86.7 |
| ACE-0 | 8.2 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 75 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 101.1 |
| ACE-650 | 89.6 |
| ACE-0 | 7.4 |
Sum of PID and PAR Scores (PRID) at each Assessment Time point - pain intensity and pain relief were evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain for pain intensity and 0 = no relief and 100 = complete relief for pain relief (NCT01115673)
Timeframe: 90 Minutes
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 104.2 |
| ACE-650 | 91.2 |
| ACE-0 | 9.4 |
Weighted Sum of the Pain Intensity Difference from Baseline Over Six Hours (SPID6) - pain intensity was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no pain and 100 = very severe pain. The total possible minimum value is -300 (worst) and the total possible maximum value is 600 (best). The weights used in the calculation of weighted sums were equal to the elapsed time (hour) between the time point of interest and the preceding time point. (NCT01115673)
Timeframe: 6 Hours
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 222.5 |
| ACE-650 | 174.3 |
| ACE-0 | -4.2 |
Weighted Sum of the Pain Relief Scores Over Six Hours (TOTPAR6) - pain relief was evaluated using a 0-100 mm visual analog scale (VAS) where 0 = no relief and 100 = complete relief. The total possible minimum value is 0 (worst) and the total possible maximum value is 600 (best). The weights used in the calculation of weighted sums were equal to the elapsed time (hour) between the time point of interest and the preceding time point. (NCT01115673)
Timeframe: 6 Hours
| Intervention | units on a scale (Least Squares Mean) |
|---|---|
| ACE-1000 | 306.9 |
| ACE-650 | 253.0 |
| ACE-0 | 64.3 |
Minutes until confirmed perceptible pain relief was achieved. A stopwatch was provided to the subject after ingestion of the study medication. The subject was instructed to stop the stopwatch when they first began to feel any pain relieving effect whatsoever of the drug, that was when they first felt any pain relief. It did not necessarily mean they felt completely better, although they might have, but when they first felt any difference in the pain. (NCT01115673)
Timeframe: within 6 Hours
| Intervention | Minutes (Median) |
|---|---|
| ACE-1000 | 22.2 |
| ACE-650 | 22.2 |
| ACE-0 | NA |
Minutes until meaningful pain relief was achieved. A stopwatch was provided to the subject after ingestion of the study medication. The subject was instructed to stop the stopwatch when the relief from the starting pain was meaningful to them. (NCT01115673)
Timeframe: within 6 Hours
| Intervention | Minutes (Median) |
|---|---|
| ACE-1000 | 53.7 |
| ACE-650 | 56.1 |
| ACE-0 | NA |
The Opioid-Related Symptom Distress Scale (ORSDS) is a Likert scale that evaluates 3 symptom distress dimensions (frequency, severity, bothersomeness) for 12 symptoms. Frequency is rated on a 4-point scale (1= 'Rarely', 4= 'Almost constantly'). Severity is rated on a 4-point scale (1= 'Slightly', 4= 'Very'). Bothersomeness is rated on a 5-point scale (0.8= 'Not at all', 4.0= 'Very much'). The symptom-specific ORSDS is the average of the 3 symptom distress dimensions. The composite ORSDS score is the average of 12 symptom-specific scores. (NCT03020966)
Timeframe: 24 hours after surgery (Post-operative day 1)
| Intervention | score on a scale (Mean) |
|---|---|
| Oral Tylenol | 0.4 |
| Intravenous Tylenol | 0.3 |
Oral morphine equivalents, cumulative, POD 0-3. Recorded in Medication Usage Database. (NCT03020966)
Timeframe: Day of surgery to post-operative day 3
| Intervention | Oral Morphine Equivalent (mg) (Mean) |
|---|---|
| Oral Tylenol | 108 |
| Intravenous Tylenol | 121 |
Numerical rating scale of pain on a scale of 0-10, with 0 representing the minimum value of no pain and 10, representing the maximum, defined as being pain as bad as imaginable. (NCT03020966)
Timeframe: 24 hours after the operation (post-operative day 1)
| Intervention | score on a scale (Mean) |
|---|---|
| Oral Tylenol | 3.6 |
| Intravenous Tylenol | 3.9 |
Morphine consumption over the first 24 hours (NCT01153503)
Timeframe: 24 hours post surgery
| Intervention | mg (Mean) |
|---|---|
| Ketorolac 30 mg, IV + TAP Block | 38.4 |
| TAP Block | 38.6 |
| Ketorolac 30 mg | 42.6 |
"Percentage of participants with anterior chamber cell grade of 0 (absence of cells)" (NCT04249076)
Timeframe: Day 8
| Intervention | Participants (Count of Participants) |
|---|---|
| Clobetasol Propionate | 38 |
| Placebo | 7 |
"Percentage of participants with VAS pain score of 0 (no eye pain)" (NCT04249076)
Timeframe: Day 8
| Intervention | Participants (Count of Participants) |
|---|---|
| Clobetasol Propionate | 68 |
| Placebo | 31 |
"Percentage of participants with anterior chamber cell grade of 0 (absence of cells)" (NCT04246801)
Timeframe: Day 8
| Intervention | Participants (Count of Participants) |
|---|---|
| Clobetasol Propionate | 67 |
| Placebo | 18 |
"Percentage of participants with VAS pain score of 0 (no eye pain). Pain was scored by ticking on a continuous scale comprised of a 10 cm horizontal line anchored by two verbal descriptions: no eye pain (score of 0) and worst imaginable eye pain (score of 10)." (NCT04246801)
Timeframe: Day 8
| Intervention | Participants (Count of Participants) |
|---|---|
| Clobetasol Propionate | 83 |
| Placebo | 19 |
"The primary outcome measure was the change in patients assessment of pain after cesarean (CS) from baseline.~For pain assessment a visual analog scale (VAS) was used. Women were asked to quantify pain using an eleven point numerical rating score from 0 to 10, with 0 indicating no pain, and 10 the worst pain.~Single value were calculated (averaged)." (NCT01115101)
Timeframe: Pain level was evaluated before therapy (2h after CS), 12h, 24h, 32h, 40h, 48 and 72h after CS.
| Intervention | VAS score at 24 hours (Mean) |
|---|---|
| Oxycodon | 5.88 |
| Patient Controlled Device With Pritramid | 4.85 |
opioid consumption (morphine equivalents)post operatively (NCT01250002)
Timeframe: 24 hours
| Intervention | mg (Median) |
|---|---|
| Group A (Study Group) Lidocaine | 20 |
| Placebo | 30 |
Quality of recovery 40 score on the day after surgery. Scale ranges from a low of 40 (poor recovery) to a high of 200 (good recovery). (NCT01250002)
Timeframe: 24 hours post surgery
| Intervention | units on a scale (Median) |
|---|---|
| Group A (Study Group) Lidocaine | 175 |
| Placebo | 157.5 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 168 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 5.22 |
| Gentlewave Treatment Group | 2.78 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 24 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 19.33 |
| Gentlewave Treatment Group | 7.78 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 6 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 23.2 |
| Gentlewave Treatment Group | 11.56 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 72 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 13.11 |
| Gentlewave Treatment Group | 5 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 168 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 8 |
| Gentlewave Treatment Group | 6 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 24 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 25 |
| Gentlewave Treatment Group | 21 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 6 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 22 |
| Gentlewave Treatment Group | 24 |
"To determine whether treatment with the Gentlewave system will significantly change the level of post-operative pain following endodontic treatment as measured by the VAS scale.~Pain measurements were made using a 0-100 VAS- NRS. The '0' mark represented 'no pain' and the '100' mark represented 'the worst pain imaginable'. Scores 0-19 represented low pain, 20-39 was mild pain, 40-59 was moderate pain, 60-79 was high pain, and 80-100 was very high or severe pain. For this study, scores in the very high range were considered severe pain." (NCT03635515)
Timeframe: 72 hours
| Intervention | score on VAS scale (Mean) |
|---|---|
| Standard Protocol (Control) Group | 17 |
| Gentlewave Treatment Group | 15 |
Average number of post-operative days with pain score >4/10. Pain score assessments were administered once daily by parents using either the Numeric Rating Scale (NRS-11) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 8-15 (von Baeyer et al., 2009) or the Faces Pain Scale-Revised (FPS-R) (with anchors 0=no pain and 10=highest pain imaginable) for children ages 4-10 (Hicks et al., 2001). (NCT01267136)
Timeframe: Efficacy was assessed daily during the 10-day postoperative recovery period.
| Intervention | days (Median) |
|---|---|
| Capital® With Codeine Suspension | 1.5 |
| Tramadol Suspension | 1 |
Parent-reported side effects entered in 10-day diary. (NCT01267136)
Timeframe: Side effects will be observed and recorded daily by caregivers for a total of 10 days in the take-home diary.
| Intervention | participants (Number) | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|
| Nausea | Vomiting | Fever | Itching | Rash | Sweating | Dizziness | Headache | Constipation | Oversedation | Tonsil bleed | |
| Capital® With Codeine Suspension | 20 | 21 | 11 | 5 | 1 | 9 | 15 | 12 | 21 | 14 | 3 |
| Tramadol Suspension | 20 | 18 | 10 | 12 | 1 | 7 | 17 | 17 | 21 | 8 | 0 |
Ambulation distance walked by participants 24-hours post-operatively (NCT00620828)
Timeframe: 24 hours post-op
| Intervention | Feet (Median) |
|---|---|
| Block Group | 38.4 |
| Control Group | 26.4 |
Participants were asked to rate their pain on a scale of 0 to 10 at all time intervals up to 24 hours post-injection. Scores were organized into the following categories: 3 or less (mild pain), 4 to 6 (moderate pain), 7 or higher (severe pain). (NCT00620828)
Timeframe: Post-anesthesia care unit (PACU), 4 hours, 8 hours, 12 hours and 24 hours post-injection
| Intervention | units on a scale (Mean) | ||||
|---|---|---|---|---|---|
| PACU | 4 hours | 8 hours | 12 hours | 24 hours | |
| Block Group | 0.67 | 2.5 | 3.8 | 3.2 | 3.9 |
| Control Group | 1.6 | 3.6 | 4.9 | 3.9 | 4.9 |
Straight Leg Raise (SLR): number of people that can perform a SLR at designated intervals (NCT00620828)
Timeframe: 4 hours, 8 hours, 12 hours and 24 hours post-op
| Intervention | participants (Number) | |||
|---|---|---|---|---|
| SLR 4 hrs | SLR 8 hrs | SLR 12 hrs | SLR 24 hrs | |
| Block Group | 4 | 13 | 12 | 13 |
| Control Group | 5 | 5 | 5 | 6 |
Knee extension and knee flexion measured at 24-hours post-operatively for patient cohort (NCT00620828)
Timeframe: 24 hours post-op
| Intervention | degrees (Mean) | |
|---|---|---|
| Knee extension | Knee flexion | |
| Block Group | 7.8 | 71.5 |
| Control Group | 7.0 | 69.6 |
The PCA total dose at the 4-hour, 8-hour, 12-hour and 24-hour post-operative time points. (NCT00620828)
Timeframe: 4 hours to 24 hours post-op
| Intervention | micrograms (Mean) | |||
|---|---|---|---|---|
| 4 hours | 8 hours | 12 hours | 24 hours | |
| Block Group | 22.4 | 95.6 | 173.4 | 418.5 |
| Control Group | 43.7 | 126.6 | 205.6 | 292.2 |
Duration of delirium will be analyzed, measured from 24 hours post-operation and daily until discharge. Additional measurements will be made at 1 month and 1 year after discharge. Delirium will be defined as an acute change in pre-operative baseline condition with additional features of inattention and either disorganized thinking and altered loss of consciousness, as defined by the Confusion Assessment Method (CAM). (NCT02546765)
Timeframe: Participants will be followed for the duration of the hospital stay, an average of 6 days, and at 1 month and 1- year following the date of surgery
| Intervention | days (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 1 |
| Acetaminophen and Propofol | 1 |
| Placebo and Dexmedetomidine | 1 |
| Placebo and Propofol | 3 |
The follow up incidence of cognitive dysfunction will be analyzed at 1 month after discharge. T-MoCA is Telephone Montreal Cognitive Assessment Scale (MOCA). The T-MoCA is scored out of 22. The minimum score is 0 (worst) and maximum score is 22 (best). T-MOCA is converted back to 30 (full MOCA) with the help of conversion algorithms to a full MOCA.Example: 19/22 converts back to 30 by performing the following equation: (19×30) ÷ 22. The total converted score is 25.9 or 26/30 which is considered in the normal range. (NCT02546765)
Timeframe: Patients will be assessed for cognitive dysfunction with T-MOCA at 1 month following the date of surgery
| Intervention | units on a scale (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 17 |
| Acetaminophen and Propofol | 18 |
| Placebo and Dexmedetomidine | 19 |
| Placebo and Propofol | 18 |
Defined by the number of days admitted in the hospital following the completion of surgery. (NCT02546765)
Timeframe: Measured in days admitted in the hospital, an average of 6 days
| Intervention | days (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 8 |
| Acetaminophen and Propofol | 8 |
| Placebo and Dexmedetomidine | 9 |
| Placebo and Propofol | 8 |
Defined by the number of days admitted in the ICU prior to transfer to the general cardiac surgical floor (NCT02546765)
Timeframe: Measured in days admitted in the ICU, an average of 2 days
| Intervention | hours (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 28.8 |
| Acetaminophen and Propofol | 30.3 |
| Placebo and Dexmedetomidine | 49.1 |
| Placebo and Propofol | 29.3 |
Incidence of delirium will be analyzed between patients treated with and without IV acetaminophen, measured from 24 hours post-operation and daily until discharge. Delirium will be defined as an acute change in pre-operative baseline condition with additional features of inattention and either disorganized thinking and altered loss of consciousness, as defined by the Confusion Assessment Method (CAM). (NCT02546765)
Timeframe: Participants will be followed for the duration of the hospital stay, an average of 5 days
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen and Dexmedetomidine | 2 |
| Acetaminophen and Propofol | 4 |
| Placebo and Dexmedetomidine | 8 |
| Placebo and Propofol | 9 |
MoCA scores at discharge will be reported in order to assess the occurrence of postoperative cognitive decline. Blinded study staff trained in administering the assessments will collect the data. MoCA is scored on a scale from 0 [worst] to 30 [best]; ǂA MoCA score of 24 would be equivalent to an Mini-Mental State Examination (MMSE) of about 27 or 28. Depending on education and peak intellectual attainment, such a score could be consistent with being either cognitively normal, or having very early mild cognitive impairment. Certainly such a person would be capable of living independently in the community and managing most or all of their affairs. (NCT02546765)
Timeframe: On the day of discharge, an average of 6 days
| Intervention | score on a scale (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 23 |
| Acetaminophen and Propofol | 24 |
| Placebo and Dexmedetomidine | 24 |
| Placebo and Propofol | 23 |
Defined by the amount of additional opioid (IV morphine or hydromorphone) and oral acetaminophen medications required in the first 48 hours postoperatively. Values will be converted to morphine equivalents for analysis. Total morphine equivalent is calculated as the sum of (fentanyl dose x 100)+(hydromorphone dose x 4)+morphine dose+(oxycodone dose x 1.5) (NCT02546765)
Timeframe: Participants will be followed for the first 48 hours postoperatively.
| Intervention | mcg (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 10050 |
| Acetaminophen and Propofol | 12611 |
| Placebo and Dexmedetomidine | 11382 |
| Placebo and Propofol | 12616 |
Severity of delirium will be analyzed, measured from 24 hours post-operation and daily until discharge. The worst severity experienced while in the hospital will be analyzed. Delirium will be defined as an acute change in pre-operative baseline condition with additional features of inattention and either disorganized thinking and altered loss of consciousness, as defined by the Confusion Assessment Method Severity Score (CAM-S, Confusion Assessment Method-Severity). range 0 [best/no delirium] to 19 [worst]; Minimal Clinical Important Difference (MCID) 2 points (NCT02546765)
Timeframe: Participants will be followed for the duration of the hospital stay, an average of 6 days
| Intervention | units on a scale (Median) |
|---|---|
| Acetaminophen and Dexmedetomidine | 10 |
| Acetaminophen and Propofol | 8 |
| Placebo and Dexmedetomidine | 6 |
| Placebo and Propofol | 9 |
Determine which of three different TAP formulations (Placebo, TAP, Clo-TAP) has the most beneficial effect on the postoperative area of hyperalgesia 48hrs after the start of the cesarean section. The smaller the area of WHA, assessed in cm2, the better the outcome. Area sizes may range from 0 to any size. (NCT01015807)
Timeframe: 48hrs after CS
| Intervention | cm^2 (Mean) |
|---|---|
| Placebo | 1.07 |
| TAP (Bupi) | 1.27 |
| Clo-TAP (Bupi + Clon) | 0.74 |
Post- operative VAS pain scores (range of 0-10. 0 being no pain and 10 being worst pain) will be recorded at 1,12, 24, 36,48 and 60 hours. The values at each time points were combined and averaged. (NCT02475031)
Timeframe: up to 60 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo Group (TAP-S) | 5.31 |
| Active Group (TAP-C) | 5.06 |
Post-operative nausea scores will be recorded at 48 hours. Range of nausea score is 0-3. 0= None, 1=Mild, 2=Moderate, 3=Severe. (NCT02475031)
Timeframe: up to 48 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo Group (TAP-S) | 0.34 |
| Active Group (TAP-C) | 0.34 |
All narcotic usage will be recorded at 1,12,24,36,48, and 60 hours. All narcotics will be converted to morphine equivalent for statistical calculation. These values reflect the total amount of narcotic used after combining all the data collected from each time point. (NCT02475031)
Timeframe: up to 60 hours
| Intervention | mg (Mean) |
|---|---|
| Placebo Group (TAP-S) | 14.31 |
| Active Group (TAP-C) | 14.40 |
Post-operative sedation scores will be recorded at 48 hours. Range of score is 0-3. 0=Awake and Alert, 1=Quietly Awake, 2=Asleep and Arousable, 3=Deep sleep. (NCT02475031)
Timeframe: 48 hours
| Intervention | units on a scale (Mean) |
|---|---|
| Placebo Group (TAP-S) | 0.2 |
| Active Group (TAP-C) | 0.06 |
The primary endpoint of this study will be narcotic requirement at 48 hours (NCT02475031)
Timeframe: 48 hours
| Intervention | mg (Mean) |
|---|---|
| Placebo Group (TAP-S) | 2.44 |
| Active Group (TAP-C) | 2.88 |
Total dose of morphine equivalents (IV equivalent of morphine) taken by the participant 0-24 hours after completion of the TAP block. (NCT01170702)
Timeframe: 24 hours
| Intervention | Morphine equivalents (mg) (Median) |
|---|---|
| Group 1 | 54 |
| Group 2 | 38 |
| Group 3 | 32 |
| Group 4 | 45 |
Total dose of morphine equivalents (IV equivalent of morphine) taken by the participant 24-72 hours after completion of the TAP block. (NCT01170702)
Timeframe: 24-72 hours
| Intervention | Morphine equivalents (mgs) (Median) |
|---|---|
| Group 1 | 67 |
| Group 2 | 60 |
| Group 3 | 67 |
| Group 4 | 67 |
Total dose of morphine equivalents (IV equivalent of morphine) taken by the participant 0-72 hours after completion of the TAP block. (NCT01170702)
Timeframe: 72 hours
| Intervention | Morphine equivalents (mgs) (Median) |
|---|---|
| Group 1 | 120 |
| Group 2 | 96 |
| Group 3 | 98 |
| Group 4 | 112 |
Pain burden at rest calculated as area under the pain score * time (hr) curve 0-72 hours. (NCT01170702)
Timeframe: 72 hours
| Intervention | score on scale * (hr) (Median) |
|---|---|
| Group 1 | 129 |
| Group 2 | 79 |
| Group 3 | 79 |
| Group 4 | 151 |
Pain burden with movement calculated as area under the pain score * time (hr) curve 0-72 hours. (NCT01170702)
Timeframe: 72 hours
| Intervention | pain score * time (hr) curve 72 hours (Median) |
|---|---|
| Group 1 | 265 |
| Group 2 | 202 |
| Group 3 | 233 |
| Group 4 | 327 |
The elapsed time in minutes of the first PCA (patient controlled analgesia) request in time (minutes) from the end of the TAP block. (NCT01170702)
Timeframe: Elapsed time in minutes
| Intervention | Minutes (Mean) |
|---|---|
| Group 1 | 90 |
| Group 2 | 118 |
| Group 3 | 126 |
| Group 4 | 83 |
Pain scores at rest ( 0 low 10 high) using an 11 point VRS (verbal pain scale) at the following hour time points, at the first request for patient controlled analgesia (PCA) then at 2,6,24,and 74 hours after the first request for PCA (patient controlled analgesia). (NCT01170702)
Timeframe: Request for first patient controlled analgesia then at 2,6,24,72 hours after initial PCA request
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| At first PCA request | 2 hous after first PCA request | 6 hours after first PCA request | 24 hours after first PCA request | 72 hours after first PCA reqest | |
| Group 1 | 3 | 3 | 3 | 2 | 1 |
| Group 2 | 3 | 1 | 2 | 1 | .5 |
| Group 3 | 2 | 0 | 2 | 1 | 1 |
| Group 4 | 2 | 2 | 2 | 3 | 1 |
Pain scores with movement ( 0 low 10 high) using an 11 point VRS (verbal pain scale) at the first request for patient controlled analgesia (PCA) then at 2,6,24,and 74 hours after the first request for PCA (patient controlled analgesia). (NCT01170702)
Timeframe: First PCA request then at 2,6,24,72 hours after first PCA request.
| Intervention | units on a scale (Median) | ||||
|---|---|---|---|---|---|
| At first PCA request | 2 hous after first PCA request | 6 hours after first PCA request | 24 hours after first PCA request | 72 hours after first PCA reqest | |
| Group 1 | 5 | 4 | 4 | 4 | 3.5 |
| Group 2 | 3.5 | 2 | 4 | 3 | 2 |
| Group 3 | 3.5 | 3 | 5 | 4 | 3 |
| Group 4 | 4 | 3 | 4 | 5 | 4 |
Using the Faces Pain Scale, the pediatric patient will indicate his/her pain level at scheduled intervals (7 times per day) for 14 days post-surgery.The Faces Pain Scale Revised is a dimensionless 10 point likert scale used to assess self-reported pain intensity on a scale from 0 (no pain) to 10 (most pain you can imagine). Greater pain scores are indicative of more severe pain. For this analysis, participant pain scores were summed and the mean per group was calculated. Total summed scores could range from 0 to 980. (NCT02296840)
Timeframe: 2 weeks after surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Ibuprofen | 158.95 |
| Hydrocodone-acetaminophen | 219.94 |
The occurrence of post-operative bleeding at the surgical site for each participant will be assessed by review of the participant's study records and clinical records and by questioning the caregiver in follow-up. If postoperative bleeding has occurred, details of the episode of bleeding will also be obtained (requirement for surgical intervention, observation at home, or observation at the hospital). (NCT02296840)
Timeframe: 2 weeks after surgery
| Intervention | Participants (Count of Participants) |
|---|---|
| Ibuprofen | 2 |
| Hydrocodone-acetaminophen | 0 |
Forced Expiratory Volume (FEV1) is the measurement of how much air, in volume, that a person can exhale with a forced breath. It is measured using a spirometer device. (NCT02922153)
Timeframe: 48-hours post-surgery
| Intervention | Liters (L) (Least Squares Mean) |
|---|---|
| Cryoanalgesia + SOC | 1.2 |
| Standard of Care | 0.93 |
The Visual Analogue Scale (VAS) uses a picture of a linear scale that shows numbers 0-10 with 0 being the least amount of pain and 10 being the most amount of pain. This outcome looked at pain in the surgical region specifically. (NCT02922153)
Timeframe: 48-hours post-surgery
| Intervention | units on a scale (Mean) |
|---|---|
| Cryoanalgesia + SOC | 2.82 |
| Standard of Care | 3.06 |
Oral endotracheal intubation is where a patient has a tube placed down their throat and into the trachea, the large airway from the mouth to the lungs. This is done to ensure that patients who are asleep under anesthesia are able to fully breath. This outcome measured the hours from the time the patient leaves the operating room until they were extubated, or had the tube removed from their trachea. (NCT02922153)
Timeframe: Hours until patient is extubated from time patient leaves the operating room
| Intervention | Hours (Mean) |
|---|---|
| Cryoanalgesia + SOC | 8.85 |
| Standard of Care | 7.33 |
Spirometry assessments measured included: forced expiratory volume (FEV1), forced vital capacity (FVC) and slow vital capacity (SVC), all of which are measured with a spirometer. FEV1 is the amount of air forcibly expired during the first second of breath, FVC is the total volume of air expired over the whole forced breath and SVC is the total volume over the whole breath but at a slow pace, not forced. (NCT02922153)
Timeframe: 48-hours post-extubation
| Intervention | Liters (L) (Mean) | ||
|---|---|---|---|
| FEV1 | FVC | SVC | |
| Cryoanalgesia + SOC | 1.20 | 1.60 | 1.52 |
| Standard of Care | 0.93 | 1.33 | 1.28 |
The Visual Analogue Scale (VAS) uses a picture of a linear scale that shows numbers 0-10 with 0 being the least amount of pain and 10 being the most amount of pain. This outcome looked at pain in the surgical region specifically. (NCT02922153)
Timeframe: 72-, 96- and 120-hours Post-Op
| Intervention | units on a scale (Mean) | ||
|---|---|---|---|
| 72 Hours Post-Op | 96 Hours Post-Op | 120 Hours Post-Op | |
| Cryoanalgesia + SOC | 2.08 | 1.84 | 2.50 |
| Standard of Care | 1.44 | 2.00 | 2.40 |
Allodynia is pain around surgical site. It is pain that occurs from stimuli that are not normally painful such as a light touch or a brush of hair around where the surgery took place. (NCT02922153)
Timeframe: 3 and 6 Months
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| 3 Month | 6 Month | |
| Cryoanalgesia + SOC | 0 | 1 |
| Standard of Care | 0 | 0 |
Patient Controlled Analgesia (PCA) is when the patient chooses to give themselves some form of analgesia, or painkiller, depending on their post-operation pain levels. Oral opioid consumption is the measure of all painkiller medicine that was prescribed by the hospital to the patient to take. This outcome measures each of these up to each time point and also measures the total PCA and oral opioid consumption post-procedure for the whole hospital stay. (NCT02922153)
Timeframe: 24-, 48, -96 and 120-hours
| Intervention | Morphine Milligram Equivalent (MME) (Mean) | ||||
|---|---|---|---|---|---|
| 24 Hours | 48 Hours | 96 Hours | 120 Hours | Total Post-Procedure for Hospital Stay | |
| Cryoanalgesia + SOC | 11.43 | 20.91 | 14.87 | 14.10 | 33.43 |
| Standard of Care | 17.32 | 31.05 | 16.67 | 13.13 | 38.31 |
The outcome measures the time spent in the intensive care unit (ICU) as well as the total hospital length of stay. (NCT02922153)
Timeframe: Procedure to Discharge
| Intervention | Days (Mean) | |
|---|---|---|
| ICU Length of Stay | Hospital Length of Stay | |
| Cryoanalgesia + SOC | 4.96 | 9.40 |
| Standard of Care | 2.96 | 6.32 |
Ambulatory Movement, defined as the subjects ability to sit up, stand up, walk and flex both the left and right shoulders, was measured at multiple time points during hospital stay. (NCT02922153)
Timeframe: Baseline, 48, 72, 96, 120 Hours and Discharge
| Intervention | Participants (Count of Participants) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| Baseline - Able to sit up in bed72559592 | Baseline - Able to sit up in bed72559593 | Baseline - Able to stand up72559593 | Baseline - Able to stand up72559592 | Baseline - Able to walk72559593 | Baseline - Able to walk72559592 | Baseline - Right shoulder flexion movement72559592 | Baseline - Right shoulder flexion movement72559593 | Baseline - Left shoulder flexion movement72559593 | Baseline - Left shoulder flexion movement72559592 | 48 Hours - Able to sit up in bed72559592 | 48 Hours - Able to sit up in bed72559593 | 48 Hours - Able to stand up72559592 | 48 Hours - Able to stand up72559593 | 48 Hours - Able to walk72559592 | 48 Hours - Able to walk72559593 | 48 Hours - Right shoulder flexion movement72559592 | 48 Hours - Right shoulder flexion movement72559593 | 48 Hours - Left shoulder flexion movement72559592 | 48 Hours - Left shoulder flexion movement72559593 | 72 Hours - Able to sit up in bed72559592 | 72 Hours - Able to sit up in bed72559593 | 72 Hours - Able to stand up72559592 | 72 Hours - Able to stand up72559593 | 72 Hours - Able to walk72559592 | 72 Hours - Able to walk72559593 | 72 Hours - Right shoulder flexion movement72559592 | 72 Hours - Right shoulder flexion movement72559593 | 72 Hours - Left shoulder flexion movement72559592 | 72 Hours - Left shoulder flexion movement72559593 | 96 Hours - Able to sit up in bed72559592 | 96 Hours - Able to sit up in bed72559593 | 96 Hours - Able to stand up72559592 | 96 Hours - Able to stand up72559593 | 96 Hours - Able to walk72559592 | 96 Hours - Able to walk72559593 | 96 Hours - Right shoulder flexion movement72559592 | 96 Hours - Right shoulder flexion movement72559593 | 96 Hours - Left shoulder flexion movement72559592 | 96 Hours - Left shoulder flexion movement72559593 | 120 Hours - Able to sit up in bed72559592 | 120 Hours - Able to sit up in bed72559593 | 120 Hours - Able to stand up72559593 | 120 Hours - Able to stand up72559592 | 120 Hours - Able to walk72559593 | 120 Hours - Able to walk72559592 | 120 Hours - Right shoulder flexion movement72559593 | 120 Hours - Right shoulder flexion movement72559592 | 120 Hours - Left shoulder flexion movement72559593 | 120 Hours - Left shoulder flexion movement72559592 | Discharge - Able to sit up in bed72559592 | Discharge - Able to sit up in bed72559593 | Discharge - Able to stand up72559592 | Discharge - Able to stand up72559593 | Discharge - Able to walk72559592 | Discharge - Able to walk72559593 | Discharge - Right shoulder flexion movement72559592 | Discharge - Right shoulder flexion movement72559593 | Discharge - Left shoulder flexion movement72559592 | Discharge - Left shoulder flexion movement72559593 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| No | Yes - Independently | Yes - with assistance | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 65 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 64 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 63 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 27 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 21 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 38 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 16 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 26 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 33 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 43 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 47 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 9 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 39 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 20 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 10 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 28 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 41 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 5 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 49 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 15 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 12 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 10 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 3 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 32 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 8 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 19 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 1 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 11 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 11 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 13 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 36 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 30 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 12 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 23 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 17 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 34 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 37 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 53 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 19 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 0 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 51 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 17 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 7 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 50 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 8 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 2 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 54 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Standard of Care | 16 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 6 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 5 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Cryoanalgesia + SOC | 4 | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Total opioid use in the post operative care unit (Mg of morphine equivalents) (NCT01755234)
Timeframe: PACU admission to discharge
| Intervention | miligrams of morphine equivalents (Median) |
|---|---|
| Sevoflurane | 9 |
| Propofol | 9.4 |
Opioid use in mg of morphine equivalents from discharge from the post anesthesia care unit to 24 hours after PACU discharge. (NCT01755234)
Timeframe: Discharge from PACU to 24 hours post operative after PACU discharge.
| Intervention | mg morphine equivalents (Median) |
|---|---|
| Sevoflurane | 30 |
| Propofol | 25 |
"Numeric rating scale for pain on a scale of 0-10 (0 is no pain and 10 is high pain) versus time curve in the post anesthesia care unit ( score * min). A higher value indicates more pain and time in the Post Anesthesia Care Unit.~The range is 0 pain to x time in minutes x 1 hour to 5 hour ( 60-300 minutes) . The pain scores were collected at 15 minute intervals from the time of admission to the PACU. The area under the NRS pain scale versus time curve was calculated using the trapezoidal method as an indicator of pain burden during early recovery (Graph Pad Prism ver 5.03, Graph Pad Software INC." (NCT01755234)
Timeframe: Time in the post anesthesia care unit
| Intervention | Pain Score * minutes in PACU (Median) |
|---|---|
| Sevoflurane | 270 |
| Propofol | 240 |
Quality of recovery score 24 hours after the surgical procedure.Score of 40 is poor recovery and a score of 200 is good recovery. (NCT01755234)
Timeframe: 24 hours after the surgical procedure
| Intervention | units on a scale (Median) |
|---|---|
| Sevoflurane | 175 |
| Propofol | 176 |
Each patient will be interviewed by a member of the study team 12 hours after receiving their spinal anesthetic (which will include either hydromorphone or morphine). Patients will be asked to rate their current level of pain on a scale of 0 (no pain) to 10 (worst pain imaginable). A pain score <4 will be considered a success. The up-down sequential allocation method will be used to determine the dose (mcg) of IT hydromorphone and IT morphine for subsequent patients (NCT02009722)
Timeframe: 12 hours after administration of spinal anesthesia
| Intervention | micrograms (Number) |
|---|---|
| Intrathecal Hydromorphone | 75 |
| Intrathecal Morphine | 150 |
Patients will be evaluated by a member of the study team at 12 hours after spinal administration. The number of patients with moderate or severe nausea will be recorded. (NCT02009722)
Timeframe: 12 hours after spinal
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 7 |
| Intrathecal Morphine | 5 |
Patients will be evaluated by a member of the study team at 24 hours after spinal administration. The number of patients with moderate or severe nausea will be recorded. (NCT02009722)
Timeframe: 24 hours after spinal
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 1 |
| Intrathecal Morphine | 4 |
Patients will be evaluated by a member of the study team at 12 hours after spinal administration. The number of patients with moderate or severe pruritus will be recorded. (NCT02009722)
Timeframe: 12 hours after spinal
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 10 |
| Intrathecal Morphine | 9 |
Patients will be evaluated by a member of the study team at 24 hours after spinal administration. The number of patients with moderate or severe pruritus will be recorded. (NCT02009722)
Timeframe: 24 hours after spinal
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 8 |
| Intrathecal Morphine | 8 |
Patients will be evaluated by a member of the study team at 6 hours after spinal administration. Patients with moderate or severe nausea will be recorded. (NCT02009722)
Timeframe: 6 hours after spinal
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 11 |
| Intrathecal Morphine | 16 |
Patients will be evaluated by a member of the study team at 6 hours after spinal administration. The number of patients with moderate or severe pruritus will be recorded. (NCT02009722)
Timeframe: 6 hours after spinal administration
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 23 |
| Intrathecal Morphine | 19 |
Patients will be evaluated by a member of the study team at 6, 12, and 24 hours after spinal administration. The presence of sedation will be graded by the Richmond Agitation Sedation Scale. Patients with a score of (-)2 or lower on the Richmond were classified as being positive for sedation. (NCT02009722)
Timeframe: 6, 12, and 24 hours after spinal administration
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 0 |
| Intrathecal Morphine | 0 |
number of patients needing medication treatment for nausea in first 24 hours (NCT02009722)
Timeframe: First 24 hours
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 13 |
| Intrathecal Morphine | 17 |
The number of patients needing medical treatment for pruritus in first 24 hours after surgery (NCT02009722)
Timeframe: First 24 hours after spinal
| Intervention | participants (Number) |
|---|---|
| Intrathecal Hydromorphone | 8 |
| Intrathecal Morphine | 4 |
Total estimated blood loss in millilitres for the surgery (NCT04175509)
Timeframe: During the duration of the surgery, from start to end time, on average 1.5 hours
| Intervention | Millilitres (Mean) |
|---|---|
| Rectal Acetaminophen | 273.53 |
| Intravenous Acetaminophen | 347.37 |
Operative time in minutes determined by the operating room record (NCT04175509)
Timeframe: From the start to end of the surgery
| Intervention | Minutes (Mean) |
|---|---|
| Rectal Acetaminophen | 88.71 |
| Intravenous Acetaminophen | 90.89 |
Total amount of opioid rescue calculated by converting all opiates to Morphine Milligram Equivalents in the first 12 hours following surgery (NCT04175509)
Timeframe: The first 12 hours following surgery
| Intervention | Morphine Milligram Equivalents (Mean) |
|---|---|
| Rectal Acetaminophen | 15.52 |
| Intravenous Acetaminophen | 14.17 |
Total amount of opioid rescue calculated by converting all opiates to Morphine Milligram Equivalents in the first 24 hours following surgery, or upon discharge, whichever comes first. (NCT04175509)
Timeframe: The first 24 hours following surgery, or upon discharge, whichever comes first.
| Intervention | Morphine Milligram Equivalents (Mean) |
|---|---|
| Rectal Acetaminophen | 25.75 |
| Intravenous Acetaminophen | 23.71 |
Total amount of opioid rescue calculated by converting all opiates to Morphine Milligram Equivalents in the first 6 hours following surgery (NCT04175509)
Timeframe: The first 6 hours following surgery
| Intervention | Morphine Milligram Equivalents (Mean) |
|---|---|
| Rectal Acetaminophen | 6.74 |
| Intravenous Acetaminophen | 7.97 |
Post-operative pain control using a standardized pain scale from 0 (no pain) to 10 (worse pain) for the first 12 hours after surgery. Time points were averaged for each participate and reported as a single value. (NCT04175509)
Timeframe: The 12 hours following surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Rectal Acetaminophen | 2.99 |
| Intravenous Acetaminophen | 3.36 |
Post-operative pain control using a standardized pain scale from 0 (no pain) to 10 (worse pain) for the first 6 hours after surgery. Time points were averaged for each participate and reported as a single value. (NCT04175509)
Timeframe: The first 6 hours following surgery
| Intervention | score on a scale (Mean) |
|---|---|
| Rectal Acetaminophen | 3.13 |
| Intravenous Acetaminophen | 1.36 |
Post-operative pain control using a standardized pain scale from 0 (no pain) to 10 (worse pain) measured every 4 hours for the 24 hours, or discharge, whichever comes first. Time points were averaged for each participate and reported as a single value. (NCT04175509)
Timeframe: The first 24 hours following surgery, or upon discharge, whichever comes first.
| Intervention | score on a scale (Mean) |
|---|---|
| Rectal Acetaminophen | 2.82 |
| Intravenous Acetaminophen | 3.18 |
Number of participants with Maximum pain intensity NVS > 3; Rescue analgesia; Nausea and Vomiting incidence; use of ondansetron for NVPO; Ondansetron being effective (number of participants for whom ondansetron was effective to stop NVPO). (NCT01597479)
Timeframe: Up to 48 hours
| Intervention | participants (Number) | |||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Maximum pain intensity 24h (NVS>3) | Maximum pain intensity 48h (NVS >3) | Rescue analgesia 24h (n) | Rescue Analgesia 48h (n) | Nausea and vomiting 24h (n) | Nausea and vomiting 48h (n) | Use of ondansetron 24h (n) | Use of ondansetron 48h (n) | Effectiveness of ondansetron 24h | Efectiveness of ondansetron 48h | |
| dPNBs Group | 8 | 5 | 2 | 5 | 1 | 0 | 1 | 0 | 1 | 0 |
| Non dPNBs Group | 24 | 21 | 17 | 17 | 10 | 5 | 5 | 5 | 4 | 2 |
Pain scores assessed using pain numerical visual scale (NVS) of 0-10 (o= no pain and 10= worst pain imaginable). We defined mild pain (NVS 0-3); moderate pain (NVS 4-6) and severe pain (NVS 7-10).The analysis of this variable at the end of the study will confirm or not the effectiveness of dPNBs for management of postoperative pain after TRA. (NCT01597479)
Timeframe: Up to 48 hours
| Intervention | percentage of patients (Number) | |
|---|---|---|
| Pain intensity NVS>3 on call 24h | Pain intensity NVS>3 on call 48h | |
| Distal Peripheral Nerve Blocks Group (dPNBs Group) | 8.3 | 4.2 |
| Non Distal Peripheral Nerve Blocks (Non dPNBs Group) | 80.8 | 42.3 |
198 reviews available for acetaminophen and Acute Post-operative Pain
| Article | Year |
|---|---|
Non-drug pain relievers active on non-opioid pain mechanisms.
Topics: Acetaminophen; Analgesics; Gabapentin; Humans; Neuralgia; Pain, Postoperative | 2022 |
Single-dose intravenous ibuprofen for acute postoperative pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Femal | 2021 |
The efficacy and safety of acetaminophen use following liver resection: a systematic review.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Hepatectomy; Humans; Liver; Morphine; Observational Studie | 2022 |
Should intravenous acetaminophen be considered for post craniotomy pain management? A meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesics, Opioid; Craniotomy; Humans; Pain Management; Pain, Postoperative; Randomi | 2022 |
Comparison of intravenous and oral administration of acetaminophen in adults undergoing general anesthesia.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesics, Opioid; Anesthe | 2022 |
Perioperative Buprenorphine Management: A Multidisciplinary Approach.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2022 |
Pain Relief with Combination Acetaminophen/Codeine or Ibuprofen following Third-Molar Extraction: A Systematic Review and Meta-Analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Codeine; Double-Blind Method; Drug Combinations; Humans; Ib | 2022 |
Nonopioid Analgesics for the Perioperative Geriatric Patient: A Narrative Review.
Topics: Acetaminophen; Acute Pain; Adult; Aged; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2022 |
Optimal management of perioperative analgesia regarding immediate and short-term outcomes after liver transplantation - A systematic review, meta-analysis and expert panel recommendations.
Topics: Acetaminophen; Analgesics, Opioid; Anesthetics, Local; Humans; Liver Transplantation; Pain Measureme | 2022 |
Paracetamol for multimodal analgesia.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, No | 2022 |
Effect of intravenous acetaminophen on postoperative outcomes in hip fracture patients: a systematic review and narrative synthesis.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Hip Fractures; Humans; Pain, Post | 2022 |
Gabapentinoids and Acetaminophen as Adjuvants for Managing Postoperative Pain.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; gamma-Aminobutyri | 2022 |
What is the best effective postoperative medication in reducing pain after non-surgical root canal treatment?
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2022 |
Pain management after total knee arthroplasty: PROcedure SPEcific Postoperative Pain ManagemenT recommendations.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents; Arthrop | 2022 |
Efficiency and Safety of Erector Spinae Plane Block in Percutaneous Nephrolithotomy: A Meta-Analysis Based on Randomized Controlled Trials.
Topics: Acetaminophen; Fentanyl; Humans; Nephrolithotomy, Percutaneous; Nerve Block; Pain, Postoperative; Ra | 2022 |
Efficacy of oxycodone for postoperative dental pain: A systematic review and meta-analysis.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Etoricoxib; Humans; Oxyc | 2022 |
Pain treatment and prophylaxis on pain.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2022 |
Intravenous acetaminophen for postoperative pain control after open abdominal and thoracic surgery in pediatric patients: a systematic review and meta-analysis.
Topics: Abdomen; Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Humans; Pain, Postoperative; Th | 2022 |
Intravenous acetaminophen for postoperative pain control after open abdominal and thoracic surgery in pediatric patients: a systematic review and meta-analysis.
Topics: Abdomen; Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Humans; Pain, Postoperative; Th | 2022 |
Intravenous acetaminophen for postoperative pain control after open abdominal and thoracic surgery in pediatric patients: a systematic review and meta-analysis.
Topics: Abdomen; Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Humans; Pain, Postoperative; Th | 2022 |
Intravenous acetaminophen for postoperative pain control after open abdominal and thoracic surgery in pediatric patients: a systematic review and meta-analysis.
Topics: Abdomen; Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Humans; Pain, Postoperative; Th | 2022 |
Acute Postoperative Pain Due to Dental Extraction in the Adult Population: A Systematic Review and Network Meta-analysis.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Human | 2023 |
Systemic opioids versus other analgesics and sedatives for postoperative pain in neonates.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Cerebral Hemorrhage; Child; Child, Preschool; Fentany | 2023 |
Glucocorticoids added to paracetamol and NSAIDs for post-operative pain: A systematic review with meta-analysis and trial sequential analysis.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Glucocorticoids; | 2023 |
Analgesia after cesarean section - what is new?
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesics, Opioid; Cesarean Section; Female; Humans; | 2023 |
Prevention of Post-Operative Pain after Elective Brain Surgery: A Meta-Analysis of Randomized Controlled Trials.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Brain; Humans; Pain, Postoperative; R | 2023 |
Opioid-Sparing Pain Control after Rhinoplasty: Updated Review of the Literature.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Gabapentin; Humans; Pain | 2023 |
Rational Multimodal Analgesia for Perioperative Pain Management.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Humans; Pain Management; Pain, Postoperati | 2023 |
Pain management after elective craniotomy: A systematic review with procedure-specific postoperative pain management (PROSPECT) recommendations.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Craniotomy; Dexmedetomidine; Hum | 2023 |
Pain management after cardiac surgery via median sternotomy: A systematic review with procedure-specific postoperative pain management (PROSPECT) recommendations.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cardiac Surg | 2023 |
Intravenous ibuprofen in postoperative pain and fever management in adults: A systematic review and meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Adult; Antipyretics; Fever; Humans; Ibuprofen; Pain, Postoperative; Randomized Contro | 2023 |
Living liver donor pain management.
Topics: Acetaminophen; Humans; Lidocaine; Liver; Pain Management; Pain, Postoperative | 2023 |
Modern Perioperative Pain Management Strategies to Minimize Opioids after Total Knee Arthroplasty.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Humans; Pain Management; Pain, P | 2023 |
PROSPECT methodology for developing procedure-specific pain management recommendations: an update.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain | 2023 |
Post-Procedure Analgesic Management.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain | 2024 |
Intravenous Acetaminophen (Paracetamol) for Postcraniotomy Pain: Systematic Review and Meta-Analysis of Randomized Controlled Trials.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Humans; Pain, Postoperative; R | 2020 |
Strategies of analgesic treatment after cesarean delivery. Current state and new alternatives.
Topics: Acetaminophen; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epi | 2020 |
Perioperative Analgesia for Patients Undergoing Thyroidectomy and Parathyroidectomy: An Evidence-Based Review.
Topics: Acetaminophen; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Bas | 2020 |
Tips and tricks in achieving zero peri-operative opioid used in onco-urologic surgery.
Topics: Acetaminophen; Analgesics, Opioid; Gabapentin; Humans; Narcotics; Pain, Postoperative | 2022 |
A systematic review and trial sequential analysis of intravenous vs. oral peri-operative paracetamol.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Humans; | 2021 |
The Efficacy and Safety of Acetaminophen in Total Joint Arthroplasty: Systematic Review and Direct Meta-Analysis.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; | 2020 |
Efficacy and Safety of Postoperative Medications in Reducing Pain after Nonsurgical Endodontic Treatment: A Systematic Review and Network Meta-analysis.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Endodontics; Humans; Net | 2020 |
Management of postoperative pain in ophthalmic plastic surgery: a major review.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ketorolac; Pain, Postoperative; Surg | 2021 |
Nonenteral Pain Management.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, No | 2020 |
Perioperative Analgesia for Sinus and Skull-Base Surgery.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; E | 2020 |
Evidence for the Efficacy of an Opioid-Sparing Effect of Intravenous Acetaminophen in the Surgery Patient: A Systematic Review.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; | 2020 |
Opioid Use and Misuse in Pregnancy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory A | 2020 |
Intravenous versus oral acetaminophen as an adjunct on pain and recovery after total knee arthroplasty: A systematic review and meta-analysis.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Knee; Huma | 2020 |
Intravenous versus oral paracetamol for postoperative analgesia: A systematic review.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Humans; Pain, Postoperative | 2021 |
Efficacy and Safety of Ibuprofen Plus Paracetamol in a Fixed-Dose Combination for Acute Postoperative Pain in Adults: Meta-Analysis and a Trial Sequential Analysis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Drug Combinations; Humans; Ibuprofen; Pain, Postoper | 2021 |
Review of Intravenous Acetaminophen for Analgesia in the Postoperative Setting.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Humans; Pain Management; Pain | 2021 |
Perioperative intravenous acetaminophen and postcesarean pain control: a systematic review and meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Opioid; Female; Humans; Pain, Postoperative; | 2021 |
Effect of Preemptive Acetaminophen on Opioid Consumption: A Meta-Analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Pain, Postoperative; Randomized | 2021 |
Pharmacological and Non-Pharmacological Methods of Postoperative Pain Control Following Oral and Maxillofacial Surgery: A Scoping Review.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Ibuprofen; Pain, | 2021 |
An Update on Multimodal Pain Management After Total Joint Arthroplasty.
Topics: Acetaminophen; Adrenal Cortex Hormones; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Ane | 2021 |
Multimodal Analgesia in Head and Neck Free Flap Reconstruction: A Systematic Review.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Free Tissue F | 2022 |
Pharmacology of Acetaminophen, Nonsteroidal Antiinflammatory Drugs, and Steroid Medications: Implications for Anesthesia or Unique Associated Risks.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Anti-Inflammatory Agents, N | 2017 |
An Update on Nonopioids: Intravenous or Oral Analgesics for Perioperative Pain Management.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug T | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Postoperative Multimodal Analgesia Pain Management With Nonopioid Analgesics and Techniques: A Review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2017 |
Intravenous paracetamol or intravenous propacetamol can provide effective postoperative analgesia for some patients.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Double-Blind Method; Humans; Pain, Postoperative | 2017 |
Postcesarean delivery analgesia.
Topics: Acetaminophen; Analgesia; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anes | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Control of Pain After Tonsillectomy in Children: A Review.
Topics: Ablation Techniques; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2017 |
Perioperative pain management strategies among women having reproductive surgeries.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Evidence-Based Med | 2017 |
Enhanced recovery after surgery: Pain management.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain Management; Pain, P | 2017 |
Intravenous acetaminophen as an adjunct to multimodal analgesia after total knee and hip arthroplasty: A systematic review and meta-analysis.
Topics: Acetaminophen; Administration, Intravenous; Arthroplasty, Replacement, Hip; Arthroplasty, Replacemen | 2017 |
The efficiency of intravenous acetaminophen for pain control following total knee and hip arthroplasty: A systematic review and meta-analysis.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Hip | 2017 |
Postoperative analgesia after pulmonary resection with a focus on video-assisted thoracoscopic surgery.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Humans; Nerve Block; Pain, Postoperative; Pneumonecto | 2018 |
[Pain management for cancer patients in drug-assisted rehabilitation].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2018 |
Comparison of intravenous and oral acetaminophen for pain control after total knee and hip arthroplasty: A systematic review and meta-analysis.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Arthropl | 2018 |
Benefits and harms associated with analgesic medications used in the management of acute dental pain: An overview of systematic reviews.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inf | 2018 |
Perioperative analgesia for patients undergoing endoscopic sinus surgery: an evidence-based review.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; E | 2018 |
The impact of intravenous acetaminophen on pain after abdominal surgery: a meta-analysis.
Topics: Abdomen; Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2018 |
A meta-analysis evaluates the efficacy of intravenous acetaminophen for pain management in knee or hip arthroplasty.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthrop | 2018 |
Updates on Multimodal Analgesia for Orthopedic Surgery.
Topics: Acetaminophen; Amines; Analgesia; Celecoxib; Cyclohexanecarboxylic Acids; Gabapentin; gamma-Aminobut | 2018 |
The Use of Intravenous Ibuprofen and Intravenous Acetaminophen in Surgical Patients and the Effect on Opioid Reduction.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Female; Humans; Ibuprofe | 2017 |
Efficacy of intravenous acetaminophen in multimodal management for pain relief following total knee arthroplasty: a meta-analysis.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Kne | 2018 |
Role of Multimodal Analgesia in the Evolving Enhanced Recovery after Surgery Pathways.
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Pain Management for Ambulatory Arthroscopic Anterior Cruciate Ligament Reconstruction: Evidence-Based Recommendations From the Society for Ambulatory Anesthesia.
Topics: Acetaminophen; Ambulatory Care; Ambulatory Surgical Procedures; Analgesics; Anesthesia; Anesthesia, | 2019 |
Intravenous Acetaminophen Versus Placebo in Post-bariatric Surgery Multimodal Pain Management: a Meta-analysis of Randomized Controlled Trials.
Topics: Acetaminophen; Administration, Intravenous; Analgesics; Bariatric Surgery; Humans; Obesity, Morbid; | 2019 |
Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-In | 2019 |
Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-In | 2019 |
Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-In | 2019 |
Pain management after laparoscopic hysterectomy: systematic review of literature and PROSPECT recommendations.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-In | 2019 |
Pain management in the orthopaedic trauma patient: Non-opioid solutions.
Topics: Acetaminophen; Anesthesia, Conduction; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; | 2020 |
Postoperative Pain Management in Dermatologic Surgery: A Systematic Review.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Dermatologic Surgical Procedures; Humans; Ibuprofen; | 2019 |
[Procedure specific pain management in relation to laparoscopic colonic surgery].
Topics: Abdominal Wall; Acetaminophen; Adrenal Cortex Hormones; Analgesia, Epidural; Analgesics; Analgesics, | 2013 |
Opioid-sparing effects of perioperative paracetamol and nonsteroidal anti-inflammatory drugs (NSAIDs) in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
Perioperative analgesia in pediatric surgery.
Topics: Acetaminophen; Adjuvants, Anesthesia; Analgesia; Analgesics, Opioid; Anesthesia, Conduction; Anti-In | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Single dose oral ibuprofen plus paracetamol (acetaminophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Analgesics, Non-Narcotic; Drug Combinations; | 2013 |
Combining ibuprofen and acetaminophen for acute pain management after third-molar extractions: translating clinical research to dental practice.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug C | 2013 |
Tonsillectomy and adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Codeine; Humans; Narcotics; Pain, Pos | 2013 |
Ibuprofen and/or paracetamol (acetaminophen) for pain relief after surgical removal of lower wisdom teeth.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Drug Combinations; Drug Therapy, Comb | 2013 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Postoperative pain management after total knee arthroplasty in elderly patients: treatment options.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Opioid; Anesthesia; Anesthesia, Conduction; Anti-Inflam | 2014 |
Posttonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2014 |
Intravenous acetaminophen and intravenous ketorolac for management of pediatric surgical pain: a literature review.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2014 |
Intravenous acetaminophen and intravenous ketorolac for management of pediatric surgical pain: a literature review.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2014 |
Intravenous acetaminophen and intravenous ketorolac for management of pediatric surgical pain: a literature review.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2014 |
Intravenous acetaminophen and intravenous ketorolac for management of pediatric surgical pain: a literature review.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2014 |
Is single incision pediatric endoscopic surgery more painful than standard laparoscopy in children? Personal experience and review of the literature.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Opioid; Appendectomy; Child; Child, Preschool; Ch | 2015 |
Nonopioid analgesics for postoperative pain management.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Humans; | 2014 |
Adverse effects of perioperative paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexan | 2014 |
Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexan | 2014 |
Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexan | 2014 |
Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexan | 2014 |
Post-operative analgesic effects of paracetamol, NSAIDs, glucocorticoids, gabapentinoids and their combinations: a topical review.
Topics: Acetaminophen; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexan | 2014 |
OFIRMEV: an old drug becomes new again.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Humans; | 2014 |
Immediate rescue designs in pediatric analgesic trials: a systematic review and meta-analysis.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Ste | 2015 |
Pain control after liver transplantation surgery.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Drug Therapy, Combination; Fenta | 2014 |
Single-dose systemic acetaminophen to prevent postoperative pain: a meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Databases, Bibliographic; Humans; Movement; Pain, Postopera | 2015 |
Optimizing pain management to facilitate Enhanced Recovery After Surgery pathways.
Topics: Acetaminophen; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lidocaine; Pain Managemen | 2015 |
Optimizing pain management to facilitate Enhanced Recovery After Surgery pathways.
Topics: Acetaminophen; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lidocaine; Pain Managemen | 2015 |
Optimizing pain management to facilitate Enhanced Recovery After Surgery pathways.
Topics: Acetaminophen; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lidocaine; Pain Managemen | 2015 |
Optimizing pain management to facilitate Enhanced Recovery After Surgery pathways.
Topics: Acetaminophen; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Humans; Lidocaine; Pain Managemen | 2015 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics; Caffeine; Chemotherapy, Adjuvant; Di | 2014 |
As required versus fixed schedule analgesic administration for postoperative pain in children.
Topics: Acetaminophen; Acute Pain; Adolescent; Analgesia; Analgesics; Analgesics, Opioid; Child; Child, Pres | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Best evidence in multimodal pain management in spine surgery and means of assessing postoperative pain and functional outcomes.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Steroidal; Com | 2015 |
Intravenous acetaminophen use in pediatrics.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Antipyretics; Bicycling; Body Weight; Chemic | 2015 |
Postoperative pain management.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduct | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
Laparoscopic surgery: a narrative review of pharmacotherapy in pain management.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adrenergic alpha-2 Receptor Agonists; Amines; Analgesics; An | 2015 |
The combination of non-selective NSAID 400 mg and paracetamol 1000 mg is more effective than each drug alone for treatment of acute pain. A systematic review.
Topics: Acetaminophen; Acute Pain; Anti-Inflammatory Agents, Non-Steroidal; Drug Synergism; Drug Therapy, Co | 2014 |
Use of Nonopioid Analgesics and the Impact on Patient Outcomes.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2016 |
Single dose intravenous paracetamol or intravenous propacetamol for postoperative pain.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Child; Humans; Injections, Intravenous; Pain Measureme | 2016 |
Old Drug, New Route: A Systematic Review of Intravenous Acetaminophen After Adult Cardiac Surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Cardiac Surgical Proced | 2017 |
Paracetamol (acetaminophen) for prevention or treatment of pain in newborns.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Delivery, Obstetric; Diagnostic Techniques, Ophthalmologica | 2016 |
Analgesia in the surgical intensive care unit.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Anesthesia, Conduction; Anesthetics, Local; C | 2017 |
NSAIDs in the Treatment of Postoperative Pain.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibit | 2016 |
Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anticonvulsants; Dexamethaso | 2017 |
Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anticonvulsants; Dexamethaso | 2017 |
Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anticonvulsants; Dexamethaso | 2017 |
Non-opioid pain management in benign minimally invasive hysterectomy: A systematic review.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthesia, Obstetrical; Anticonvulsants; Dexamethaso | 2017 |
The Role of Multimodal Analgesia in Spine Surgery.
Topics: Acetaminophen; Amines; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclohexaneca | 2017 |
Single dose oral paracetamol (acetaminophen) for postoperative pain in adults.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Humans; Pain, Postoperative; Randomized Controlled T | 2008 |
Peri-operative use of paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Administration Routes; Drug Administration Schedule; H | 2009 |
Single dose oral paracetamol (acetaminophen) with codeine for postoperative pain in adults.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; D | 2009 |
[Weak opioids. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Chemical and Drug Induced Liver Injur | 2009 |
Single dose oral oxycodone and oxycodone plus paracetamol (acetaminophen) for acute postoperative pain in adults.
Topics: Acetaminophen; Acute Disease; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Synergism; D | 2009 |
Codeine-acetaminophen versus nonsteroidal anti-inflammatory drugs in the treatment of post-abdominal surgery pain: a systematic review of randomized trials.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cesarean Section; Codeine; Episi | 2009 |
Evidence-based review of clinical studies on pharmacology (non-anesthetic studies).
Topics: Acetaminophen; Administration, Oral; Analgesics; Anxiety; Dental Pulp Diseases; Dexamethasone; Drug | 2009 |
What anesthesiologists should know about paracetamol (acetaminophen).
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anesthesiology; Humans; Pain, Postoperative | 2009 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Combining paracetamol (acetaminophen) with nonsteroidal antiinflammatory drugs: a qualitative systematic review of analgesic efficacy for acute postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2010 |
Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs (NSAIDs) for the reduction of morphine-related side effects after major surgery: a systematic review.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2010 |
[Treatment of acute pain during drug-assisted rehabilitation].
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents | 2010 |
Pain management: Part 1: Managing acute and postoperative dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain | 2010 |
The role of multimodal analgesia in pain management after ambulatory surgery.
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-1 Receptor Antagonists; Ambulat | 2010 |
Intravenous acetaminophen.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Clinical Trials as Topic; Fever; Humans; Inje | 2010 |
Transurethral resection of the prostate revisited and updated.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Humans; Male; Pain, Postoperative; Prostate; | 2011 |
Paracetamol and selective and non-selective non-steroidal anti-inflammatory drugs for the reduction in morphine-related side-effects after major surgery: a systematic review.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Sche | 2011 |
Use of intravenous acetaminophen in the treatment of postoperative pain.
Topics: Acetaminophen; Humans; Infusions, Intravenous; Pain, Postoperative | 2011 |
Minimum efficacy criteria for comparisons between treatments using individual patient meta-analysis of acute pain trials: examples of etoricoxib, paracetamol, ibuprofen, and ibuprofen/paracetamol combinations after third molar extraction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Drug Therapy, Combination; Etoricoxib; | 2011 |
Single-dose intravenous paracetamol or propacetamol for prevention or treatment of postoperative pain: a systematic review and meta-analysis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Drug Administration Schedule; Humans; Injecti | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Perioperative intravenous acetaminophen and NSAIDs.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; | 2011 |
Continuous multimechanistic postoperative analgesia: a rationale for transitioning from intravenous acetaminophen and opioids to oral formulations.
Topics: Acetaminophen; Administration, Oral; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug T | 2012 |
[Post-operative pain management in hospitals].
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opi | 2011 |
Multimodal systemic and intra-articular analgesics.
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Adrenergic beta-Antagonists; Ambulatory Surgica | 2011 |
Single dose intravenous propacetamol or intravenous paracetamol for postoperative pain.
Topics: Acetaminophen; Adult; Analgesics; Child; Humans; Injections, Intravenous; Pain, Postoperative; Rando | 2011 |
Tramadol hydrochloride/acetaminophen combination for the relief of acute pain.
Topics: Acetaminophen; Acute Pain; Drug Combinations; Humans; Pain, Postoperative; Tramadol | 2011 |
[Chronic pain following spine surgery].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2012 |
Caffeine as an analgesic adjuvant for acute pain in adults.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Caffeine; Chemotherapy, Adjuvant; Female; Headache; Hu | 2012 |
Mechanisms of reducing postoperative pain, nausea and vomiting: a systematic review of current techniques.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory | 2012 |
Clinical and economic evidence for intravenous acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Clinical Trials as Topic; Cost-Benefit Analysis; Drug Costs | 2012 |
The role of intravenous acetaminophen in acute pain management: a case-illustrated review.
Topics: Acetaminophen; Acute Pain; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Synergism; Femal | 2012 |
Perioperative pain control in pediatric patients undergoing orthopaedic surgery.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory | 2012 |
The role of intravenous acetaminophen in multimodal pain protocols for perioperative orthopedic patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Clinical Protocols; Humans; Infusions, Intravenous; Orthope | 2013 |
Pain control in outpatient surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anesthetics, General; | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
The efficacy of combination analgesic therapy in relieving dental pain.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2002 |
[Paracetamol in childhood. Current state of knowledge and indications for a rational approach to postoperative analgesia].
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Child; Humans; Infant, Newb | 2002 |
Treatment of postoperative pain after ophthalmic surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex | 2002 |
Treatment of postoperative pain after ophthalmic surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex | 2002 |
Treatment of postoperative pain after ophthalmic surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex | 2002 |
Treatment of postoperative pain after ophthalmic surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cataract Ex | 2002 |
Pharmacology of systemic analgesics.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dipyr | 2002 |
Meta-analysis of single dose oral tramadol plus acetaminophen in acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Do | 2003 |
Single dose oral paracetamol (acetaminophen) for postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Pain, Postoperative; Randomized Controlled Trials a | 2004 |
Relative efficacy of oral analgesics after third molar extraction.
Topics: Acetaminophen; Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Codeine; C | 2004 |
Single high-dose rectal acetaminophen in children.
Topics: Acetaminophen; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Chemistry, Pharmaceutic | 2004 |
Recent advances in postoperative pain therapy.
Topics: Acetaminophen; Acute Disease; Analgesia; Cyclooxygenase Inhibitors; Gastrointestinal Diseases; Human | 2005 |
Postoperative analgesia in infants and children.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, | 2005 |
Postoperative analgesia in infants and children.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, | 2005 |
Postoperative analgesia in infants and children.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, | 2005 |
Postoperative analgesia in infants and children.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Effects of acetaminophen on morphine side-effects and consumption after major surgery: meta-analysis of randomized controlled trials.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Syn | 2005 |
Pediatric intravenous paracetamol (propacetamol) pharmacokinetics: a population analysis.
Topics: Acetaminophen; Adolescent; Algorithms; Analgesics, Non-Narcotic; Biological Availability; Child; Chi | 2005 |
Predicting postoperative analgesia outcomes: NNT league tables or procedure-specific evidence?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Evidence-Based Medicine; Humans; Meta-Analysis as Topic; Pa | 2005 |
How high should total pain-relief score be to obviate the need for analgesic remedication in acute pain? Estimation using signal detection theory and individual-patient meta-analysis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Humans; Naproxen; Pain, Postoperative; Predi | 2006 |
State of the art of paracetamol in acute pain therapy.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Animals; Central Nervous System; Clinical Tr | 2006 |
Analgesics for pain after traumatic or orthopaedic surgery: what is the evidence--a systematic review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2006 |
Postoperative pain management: new, convenient analgesic therapies.
Topics: Acetaminophen; Analgesics; Fentanyl; Humans; Oxycodone; Pain, Postoperative | 2007 |
Clinical update: postoperative analgesia.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; C | 2007 |
Update on the role of non-opioids for postoperative pain treatment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Humans; | 2007 |
Preventing the development of chronic pain after orthopaedic surgery with preventive multimodal analgesic techniques.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesia, Epidural; Analgesics; Anesthetics, Local; Anima | 2007 |
Paracetamol for pain relief after surgical removal of lower wisdom teeth.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Molar, Third; Outcome Assessment, Health Care; Pain | 2007 |
Standardised analgesia packs after day case orthopaedic surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Attitude to Health; Codeine; D | 2007 |
The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic review.
Topics: Acetaminophen; Amines; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; An | 2007 |
The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic review.
Topics: Acetaminophen; Amines; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; An | 2007 |
The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic review.
Topics: Acetaminophen; Amines; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; An | 2007 |
The effect of analgesic technique on postoperative patient-reported outcomes including analgesia: a systematic review.
Topics: Acetaminophen; Amines; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; An | 2007 |
A review of the literature on post-operative pain in older cancer patients.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Nefopam; Neoplas | 2007 |
Post-operative pain management using patient-controlled analgesia.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Opioid; Drug Therapy, Combination; Humans; | 2008 |
Analgesic efficacy in dental pain.
Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 1982 |
Analgesic agents and strategies in the dental pain model.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Humans; Mola | 1994 |
Managing postoperative pain in the elderly.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroi | 1996 |
Analgesic efficacy of paracetamol and its combination with codeine and caffeine in surgical pain--a meta-analysis.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Codeine | 1996 |
Single-patient data meta-analysis of 3453 postoperative patients: oral tramadol versus placebo, codeine and combination analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammat | 1997 |
Paracetamol with and without codeine in acute pain: a quantitative systematic review.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Drug Therapy, C | 1997 |
Systematic overview of co-proxamol to assess analgesic effects of addition of dextropropoxyphene to paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Dextropropoxyphene; Drug Combinations; | 1997 |
The efficacy of nonopioid analgesics for postoperative dental pain: a meta-analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
Single-dose dextropropoxyphene in post-operative pain: a quantitative systematic review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Dextropropoxyphene; Humans; Pain, Posto | 1998 |
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio | 1998 |
Pain management in dental practice: tramadol vs. codeine combinations.
Topics: Acetaminophen; Adrenergic Uptake Inhibitors; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infl | 1999 |
Single dose dextropropoxyphene, alone and with paracetamol (acetaminophen), for postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Dextropropoxyphene; Drug Therapy, Combi | 2000 |
Single dose paracetamol (acetaminophen), with and without codeine, for postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Drug Therapy, Combination; Hum | 2000 |
Single dose oxycodone and oxycodone plus paracetamol (acetominophen) for acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Therapy, Combinatio | 2000 |
Non-opioid postoperative analgesia.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroida | 2000 |
Using evidence from different sources: an example using paracetamol 1000 mg plus codeine 60 mg.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Aspirin; Codeine; Drug Combinations; Dr | 2001 |
Nonsteroidal anti-inflammatory drugs and paracetamol in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Cyclooxygen | 2001 |
Acute postoperative pain management: a review.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ster | 2001 |
Interactions between systemic analgesics.
Topics: Acetaminophen; Adrenergic alpha-Agonists; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Stero | 2001 |
Combination analgesic efficacy: individual patient data meta-analysis of single-dose oral tramadol plus acetaminophen in acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Doub | 2002 |
The role of non-opioid analgesic techniques in the management of pain after ambulatory surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-In | 2002 |
The role of non-opioid analgesic techniques in the management of pain after ambulatory surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-In | 2002 |
The role of non-opioid analgesic techniques in the management of pain after ambulatory surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-In | 2002 |
The role of non-opioid analgesic techniques in the management of pain after ambulatory surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-In | 2002 |
Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2002 |
Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2002 |
Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2002 |
Comparative effect of paracetamol, NSAIDs or their combination in postoperative pain management: a qualitative review.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Metho | 2002 |
Rectal and parenteral paracetamol, and paracetamol in combination with NSAIDs, for postoperative analgesia.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Stero | 2002 |
Rectal and parenteral paracetamol, and paracetamol in combination with NSAIDs, for postoperative analgesia.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Stero | 2002 |
Rectal and parenteral paracetamol, and paracetamol in combination with NSAIDs, for postoperative analgesia.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Stero | 2002 |
Rectal and parenteral paracetamol, and paracetamol in combination with NSAIDs, for postoperative analgesia.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Stero | 2002 |
Developments in the treatment of postoperative pain in paediatrics.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anesthesia, Loc | 2002 |
Effective use of analgesic drugs.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Ast | 1976 |
Pain in neonatal circumcision.
Topics: Acetaminophen; Anesthesia, Local; Circumcision, Male; Humans; Infant, Newborn; Male; Nerve Block; Pa | 1991 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries | 1990 |
893 trials available for acetaminophen and Acute Post-operative Pain
| Article | Year |
|---|---|
Pain Management Following Otological Surgery: A Prospective Study of Different Strategies.
Topics: Acetaminophen; Adult; Aged; Analgesics; Cochlear Implantation; Codeine; Ear, Middle; Female; Humans; | 2022 |
The Effect of Scheduled Intravenous Acetaminophen in an Enhanced Recovery Protocol Pathway in Patients Undergoing Major Abdominal Procedures: A Prospective, Randomized, and Placebo-Controlled Clinical Trial.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2022 |
Comparing the efficacy of peritonsillar injection of bupivacaine and intravenous acetaminophen on post-tonsillectomy pain in children.
Topics: Acetaminophen; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Double-Blind Method; Female | 2022 |
Assessing efficacy of intravenous acetaminophen for perioperative pain control for oocyte retrieval: a randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Double-Blind Method; Female; Humans; | 2022 |
Analgesic effect of oral ibuprofen 400, 600, and 800 mg; paracetamol 500 and 1000 mg; and paracetamol 1000 mg plus 60 mg codeine in acute postoperative pain: a single-dose, randomized, placebo-controlled, and double-blind study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Codeine; Dose-Response Relationship, Drug; Double-Blin | 2021 |
Comparison of analgesic effects of Gabapentin and Paracetamol post-operatively in patients with hand injury.
Topics: Acetaminophen; Adult; Analgesics; Double-Blind Method; Female; Gabapentin; Hand Injuries; Humans; Ma | 2021 |
Effectiveness of Oxycodone Hydrochloride (Strong Opioid) vs Combination Acetaminophen and Codeine (Mild Opioid) for Subacute Pain After Fractures Managed Surgically: A Randomized Clinical Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Australia; Codeine; Double-Blind Method; Drug Combinations | 2021 |
The Use of Combination Paracetamol and Ibuprofen in Postoperative Pain after Total Knee Arthroplasty, a Randomized Controlled Trial.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Double-Blind Method; Humans; Ibu | 2021 |
Analgesic efficacy of naproxen sodium versus hydrocodone/acetaminophen in acute postsurgical dental pain: a randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2022 |
COMPARATIVE ANALGESIC EFFECTS OF SINGLE-DOSE PREOPERATIVE ADMINISTRATION OF PARACETAMOL (ACETAMINOPHEN) 500 mg PLUS CODEINE 30 mg AND IBUPROFEN 400 mg ON PAIN AFTER THIRD MOLAR SURGERY.
Topics: Acetaminophen; Analgesics; Codeine; Double-Blind Method; Humans; Ibuprofen; Molar, Third; Pain, Post | 2021 |
Are nonsteroidal anti-inflammatory drugs effective enough for postoperative pain control after functional endoscopic sinus surgery and septoplasty? A randomized, controlled study.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans; Hydr | 2022 |
Effect of dexamethasone as an analgesic adjuvant to multimodal pain treatment after total knee arthroplasty: randomised clinical trial.
Topics: Acetaminophen; Aged; Analgesics; Arthroplasty, Replacement, Knee; Dexamethasone; Double-Blind Method | 2022 |
Time to Stop Routinely Prescribing Opiates after Carpal Tunnel Release.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Canada; Carpal Tunnel Synd | 2022 |
Intravenous ibuprofen versus diclofenac plus orphenadrine in orthognathic surgery: a prospective, randomized, double-blind, controlled clinical study.
Topics: Acetaminophen; Adolescent; Adult; Diclofenac; Double-Blind Method; Humans; Ibuprofen; Middle Aged; O | 2022 |
A Randomised Control Trial Comparing Opioid and Paracetamol for Pain Control after Carpal Tunnel Release.
Topics: Acetaminophen; Analgesics, Opioid; Carpal Tunnel Syndrome; Humans; Pain, Postoperative; Prospective | 2022 |
Efficacy of Preemptive Analgesia on Tourniquet and Postoperative Pain Relief in Open Carpal Tunnel Release: A Prospective Randomized Control Trial.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Anesthetics, Local; Carpal Tunnel Syndrome; Humans; Pa | 2023 |
Gabapentin Premedication to Reduce Postoperative Pain for Pediatric Tonsillectomy/Adenoidectomy: A Pilot Study.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Aftercare; Analgesics; Analgesics, Opioid; Child; Child, P | 2022 |
Lidocaine Plus Morphine Versus Lidocaine Plus Paracetamol for Bier Block: A Double-Blind Randomized Controlled Trial.
Topics: Acetaminophen; Anesthesia, Conduction; Anesthetics, Local; Double-Blind Method; Female; Humans; Lido | 2022 |
Efficacy of Intravenous Ibuprofen and Intravenous Paracetamol in Multimodal Pain Management of Postoperative Pain After Percutaneous Nephrolithotomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Double-Bl | 2022 |
Comparison of intravenous paracetamol infusion versus intramuscular tramadol as labor analgesia: a randomized control trial.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Double-Blind Method; Female; Humans; Infant, Newborn; | 2023 |
HTX-011 in Combination with Multimodal Analgesic Regimen Minimized Severe Pain and Opioid Use after Total Knee Arthroplasty in an Open-Label Study.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Local; Arthroplasty, Replacement, Knee; | 2023 |
Opioid-sparing pain management protocol after shoulder arthroplasty results in less opioid consumption and higher satisfaction: a prospective, randomized controlled trial.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Shoulder; Bupivacaine; Celecoxib; Gaba | 2022 |
The Effect of Erector Spinae Plane Block With and Without Addition of Magnesium on Relief of Pain from Post-herpetic Neuralgia.
Topics: Acetaminophen; Analgesics; Bupivacaine; Humans; Magnesium; Magnesium Sulfate; Nerve Block; Neuralgia | 2022 |
A prospective randomized study evaluating the necessity of narcotics following ureteroscopy for urinary stone disease.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2022 |
Nerve block with liposomal bupivacaine yields fewer complications and similar pain relief when compared to an interscalene catheter for arthroscopic shoulder surgery: a randomized controlled trial.
Topics: Acetaminophen; Anesthetics, Local; Aspirin; Brachial Plexus Block; Bupivacaine; Catheters; Humans; P | 2022 |
Posterior quadratus lumborum block versus posterior transversus abdominis plane block for unilateral inguinal hernia surgery.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Hernia | 2022 |
The effect of timing of intravenous paracetamol on perioperative pain and cytokine levels following laparoscopic bariatric surgery, a randomized controlled trial.
Topics: Acetaminophen; Adult; Bariatric Surgery; Cytokines; Double-Blind Method; Humans; Laparoscopy; Pain M | 2022 |
Paracetamol, ibuprofen and dexamethasone for pain treatment after total hip arthroplasty: protocol for the randomised, placebo-controlled, parallel 4-group, blinded, multicentre RECIPE trial.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty | 2022 |
Effect of a Postoperative Multimodal Opioid-Sparing Protocol vs Standard Opioid Prescribing on Postoperative Opioid Consumption After Knee or Shoulder Arthroscopy: A Randomized Clinical Trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Ulcer Agents; Arthroscopy; | 2022 |
Efficacy of Levobupivacaine Versus Levobupivacaine Plus Dexmedetomidine Infiltration for Post-Tonsillectomy Analgesia: A Randomized Controlled Trial.
Topics: Acetaminophen; Analgesia; Analgesics; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Dexm | 2022 |
A randomized, placebo-controlled study of magnetic acupuncture for supplementary analgesia after laparoscopic appendectomy in children.
Topics: Acetaminophen; Acupuncture Therapy; Adolescent; Analgesia; Analgesics; Appendectomy; Child; Child, P | 2023 |
Ultrasound-Guided Erector Spinae Block Versus Ultrasound-Guided Thoracic Paravertebral Block for Pain Relief in Patients With Acute Thoracic Herpes Zoster: A Randomized Controlled Trial.
Topics: Acetaminophen; Acute Pain; Antiviral Agents; Bupivacaine; Dexamethasone; Herpes Zoster; Humans; Midd | 2022 |
Nociception Level Index-Directed Erector Spinae Plane Block in Open Heart Surgery: A Randomized Controlled Clinical Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Cardiac Surgical Procedures; Dexamethasone; Fentanyl; Huma | 2022 |
The Use of Dissemination and Implementation to Improve Multimodal Analgesia in Head and Neck Surgery.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Gabapentin; Humans; Ketorolac; Pain, Postoperative; Pi | 2023 |
Pain treatment after total hip arthroplasty: Detailed statistical analysis plan for the RECIPE randomised clinical trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Humans; | 2023 |
Perioperative Intravenous Lidocaine Infusion for Postlaparoscopic Cholecystectomy Pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Opioid; Anesthetics, Local; Cholecystectom | 2023 |
Additive or synergistic analgesic effect of metamizole on standard pain treatment at home after arthroscopic shoulder surgery: A randomised controlled superiority trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Humans; Ibuprofen; Pain, Postopera | 2023 |
Efficacy of Perioperative Intravenous Dexamethasone on Postoperative Analgesia in Scleral Buckle Surgery: A Randomized Clinical Trial.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Dexamethasone; Humans; Pain, Postoperative; Retinal De | 2023 |
Multimodal Analgesia and Patient Education Reduce Postoperative Opioid Consumption in Otology.
Topics: Acetaminophen; Adult; Analgesia; Analgesics, Opioid; Humans; Naproxen; Otolaryngology; Pain Manageme | 2023 |
Quality of recovery after pericapsular nerve group (PENG) block for primary total hip arthroplasty under spinal anaesthesia: a randomised controlled observer-blinded trial.
Topics: Acetaminophen; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroplasty, Replacement | 2023 |
Ultrasound-guided Techniques for Perioperative Analgesia in Pediatric Lower Abdominal Surgeries: Quadratus Lumborum Block with Bupivacaine versus Caudal Bupivacaine and Neostigmine.
Topics: Acetaminophen; Analgesia; Analgesics; Anesthetics, Local; Bupivacaine; Child; Humans; Neostigmine; P | 2023 |
Outpatient Treatment With Gabapentin in Women With Severe Acute Pain After Cesarean Delivery Is Ineffective: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Double-Blind Method; Female; Gabapentin; Humans; Ibup | 2023 |
The comparison of intraincisional bupivacaine infiltration and intravenous paracetamol administration for pain alleviation after cesarean section: a double-blinded randomized placebo controlled clinical trial.
Topics: Acetaminophen; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Cesarean Section; Double-Blind M | 2023 |
Is Acetaminophen Beneficial in Patients With Cancer Pain Who are on Strong Opioids? A Randomized Controlled Trial.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Cancer Pain; Double-Blind M | 2023 |
Analgesic effect of oral paracetamol 1000 mg/ibuprofen 400 mg, paracetamol 1000 mg/codeine 60 mg, paracetamol 1000 mg/ibuprofen 400 mg/codeine 60 mg, or placebo on acute postoperative pain: a single-dose, randomized, and double-blind study.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Codeine; Double-Blind Method; Drug-Relat | 2023 |
Efficacy of Adding Acetaminophen to Preemptive Multimodal Analgesia in Total Knee Arthroplasty: A Double-blinded Randomized Study.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Celecoxib; Double-Bli | 2023 |
Selective Inhibition of Na
Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Opioid; Double-Blind Method; Humans; Hydrocodone; | 2023 |
Combination of acetaminophen and ibuprofen is noninferior to acetaminophen and hydrocodone for postnail procedure analgesia: A randomized controlled trial.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Drug Combinations; Humans; Hydrocodone; Ibuprofe | 2023 |
Preemptive effects of etoricoxib, acetaminophen, nimesulide, and ibuprofen on postoperative pain management after single-implant surgery: A randomized clinical trial.
Topics: Acetaminophen; Dental Implants; Double-Blind Method; Etoricoxib; Female; Humans; Ibuprofen; Male; Mi | 2023 |
The evaluation of the efficacy of etofenamate spray in postoperative cesarean pain: Randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Cesarean Section; Female; Humans; Pain, Postoperative; Pregnancy; Prospective Studies | 2023 |
Evaluating Caudal Block Enhancements in Pediatric Circumcision: Do Additional Analgesics Make a Difference?
Topics: Acetaminophen; Analgesics; Anesthetics, Local; Bupivacaine; Child; Humans; Male; Meperidine; Nerve B | 2023 |
Efficacy of repeated administration of intravenous acetaminophen for pain management after total knee arthroplasty.
Topics: Acetaminophen; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Humans; Pain Management; Pain, P | 2023 |
Intravenous acetaminophen for postoperative pain in the neonatal intensive care unit: A protocol for a pilot randomized controlled trial (IVA POP).
Topics: Acetaminophen; Analgesics, Opioid; Double-Blind Method; Fentanyl; Humans; Infant, Newborn; Intensive | 2023 |
Comparison Between the Protector™ Laryngeal Mask Airway and the Endotracheal Tube for Minimally Invasive Thyroid and Parathyroid Surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Cough; Deglutition Disorders; Female; Humans; | 2019 |
Efficacy and Safety of an Intravenous Acetaminophen/Ibuprofen Fixed-dose Combination After Bunionectomy: a Randomized, Double-blind, Factorial, Placebo-controlled Trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroid | 2019 |
Randomized Population Pharmacokinetic Analysis and Safety of Intravenous Acetaminophen for Acute Postoperative Pain in Neonates and Infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Female; Humans; Infant; I | 2020 |
Assessing the effectiveness of perioperative s-ketamine on new-onset headache after resective epilepsy surgery (ESPAIN-trial): protocol for a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combinations; | 2019 |
Comparison of tramadol versus tramadol with paracetamol for efficacy of postoperative pain management in lumbar discectomy: A randomised controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Diskectomy; Drug Therapy, Combin | 2020 |
A prospective randomized trial of intravenous ketorolac vs. acetaminophen administered with opioid patient-controlled analgesia in gynecologic surgery.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inf | 2019 |
Ultrasound-guided erector spinae plane block for postoperative analgesia in pediatric patients undergoing splenectomy: A prospective randomized controlled trial.
Topics: Acetaminophen; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; Child, Presch | 2019 |
Ultrasound-guided erector spinae plane block for postoperative analgesia in pediatric patients undergoing splenectomy: A prospective randomized controlled trial.
Topics: Acetaminophen; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; Child, Presch | 2019 |
Ultrasound-guided erector spinae plane block for postoperative analgesia in pediatric patients undergoing splenectomy: A prospective randomized controlled trial.
Topics: Acetaminophen; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; Child, Presch | 2019 |
Ultrasound-guided erector spinae plane block for postoperative analgesia in pediatric patients undergoing splenectomy: A prospective randomized controlled trial.
Topics: Acetaminophen; Analgesia; Anesthesia, General; Anesthetics, Local; Bupivacaine; Child; Child, Presch | 2019 |
Benefits and harm of paracetamol and ibuprofen in combination for post-operative pain: Pre-planned subgroup analyses of the multicenter, randomized PANSAID trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; | 2020 |
Comparison of Low Pre-Emptive Oral Doses of Celecoxib Versus Acetaminophen for Postoperative Pain Management After Third Molar Surgery: A Randomized Controlled Study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Celecoxib; Double-Blind Method; Humans; Molar, Third; Pain, | 2020 |
Comparison of clinical outcomes of acetaminophen IV vs PO in the peri-operative setting for laparoscopic inguinal hernia repair surgeries: A triple-blinded, randomized controlled trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Hernia, Inguinal; | 2020 |
A randomized pilot program to reduce opioid use following dental surgery and increase safe medication return.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Male; | 2020 |
Impact of Preoperative Acetaminophen and Carbohydrate Loading on Pain and Functional Status in Patients Undergoing Mohs Micrographic Surgery for Nonmelanoma Skin Cancers.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Diet, Carbohydrate Loading; Female; Functional Status | 2020 |
Preemptive Oral Compared With Intravenous Acetaminophen for Postoperative Pain After Robotic-Assisted Laparoscopic Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Drug Adm | 2019 |
Effect of quadratus lumborum block on postoperative analgesic requirements in pediatric patients: a randomized controlled double-blinded study.
Topics: Abdomen; Abdominal Muscles; Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2020 |
An Evaluation of Ibuprofen Versus Ibuprofen/Acetaminophen for Postoperative Endodontic Pain in Patients With Symptomatic Irreversible Pulpitis and Symptomatic Apical Periodontitis.
Topics: Acetaminophen; Adult; Double-Blind Method; Endodontics; Female; Humans; Ibuprofen; Male; Pain, Posto | 2019 |
Comparing paracetamol/codeine and meloxicam for postoperative analgesia in dogs: a non-inferiority trial.
Topics: Acetaminophen; Analgesics; Animals; Codeine; Dogs; Drug Combinations; Female; Male; Meloxicam; Pain, | 2020 |
Randomized control trial of opioid- versus nonopioid-based analgesia after thyroidectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; Male; Middle | 2020 |
The analgesic efficacy of IV acetaminophen for acute postoperative pain in C-section patients: a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Double-Blind Method; | 2022 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Multimodal Analgesic Regimen for Spine Surgery: A Randomized Placebo-controlled Trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Therapy | 2020 |
Efficacy and safety of naproxen sodium 440 mg versus acetaminophen 600 mg/codeine phosphate 60 mg in the treatment of postoperative dental pain.
Topics: Acetaminophen; Codeine; Dental Care; Double-Blind Method; Humans; Naproxen; Pain, Postoperative | 2020 |
Does the pre-emptive administration of paracetamol or ibuprofen reduce trans- and post-operative pain in primary molar extraction? A randomized placebo-controlled clinical trial.
Topics: Acetaminophen; Child; Double-Blind Method; Humans; Ibuprofen; Molar; Pain, Postoperative; Tooth Extr | 2020 |
The PANSAID randomized clinical trial: A pre-planned 1-year follow-up regarding harm.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Denmark; Drug Therapy, Combination; Follow-Up S | 2020 |
Efficacy and Safety of Single and Multiple Doses of a Fixed-dose Combination of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: Results From 2 Phase 3, Randomized, Parallel-group, Double-blind, Placebo-controlled Studies.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Drug Combinations; Humans; Ibuprofen; | 2020 |
The relationship between postoperative opioid consumption and the incidence of hypoxemic events following total hip arthroplasty: a post hoc analysis.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Arthropla | 2020 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Preoperative Gabapentin for Minimally Invasive Hysterectomy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Celecoxib; Double-Blind Method; Drug Administration | 2021 |
Comparing the effects of ketorolac and Paracetamol on postoperative pain relief after coronary artery bypass graft surgery. A randomized clinical trial.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Coronary Artery Bypass; Coronary Artery Disease; Doub | 2020 |
Effect of Intravenous Paracetamol with Bupivacaine Scalp Nerve Block on Haemodynamics Response as Well as Anaesthetic Requirements during Supratentorial Craniotomies.
Topics: Acetaminophen; Adolescent; Adult; Anesthetics, Local; Bangladesh; Bupivacaine; Craniotomy; Double-Bl | 2020 |
Evaluation of Fixed-Dose Combinations of Ibuprofen and Acetaminophen in the Treatment of Postsurgical Dental Pain: A Pilot, Dose-Ranging, Randomized Study.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2020 |
Analgesic impact of buprenorphine transdermal patch in total hip arthroplasty: A randomized controlled trial protocol.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Analgesi | 2020 |
Comparison between isolated and associated with codeine acetaminophen in pain control of acute apical abscess: a randomized clinical trial.
Topics: Abscess; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blind Method; | 2021 |
Examining Reduced Opioid Prescriptions after Gynecologic Laparoscopy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Dose-Response Relationship | 2021 |
Addition of dexmedetomidine to ropivacaine for local infiltration anaesthesia improves analgesic efficacy after tonsillectomy and adenoidectomy: A randomized controlled trial.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Local; Child | 2020 |
Effect of Intravenous Acetaminophen on Postoperative Hypoxemia After Abdominal Surgery: The FACTOR Randomized Clinical Trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Female; Humans; Hy | 2020 |
Analgesia and side effects of codeine phosphate associated with paracetamol vs. paracetamol after the extraction of mandibular third molars: a randomized double-blind clinical trial using the split-mouth model.
Topics: Acetaminophen; Analgesia; Codeine; Double-Blind Method; Humans; Molar, Third; Pain, Postoperative; T | 2021 |
Comparison of preemptive paracetamol, paracetamol-diclofenac & paracetamol-tramadol combination on postoperative pain after elective abdominal surgery under general anesthesia, Ethiopia: a randomized control trial study, 2018.
Topics: Abdomen; Acetaminophen; Adult; Analgesics; Anesthesia, General; Diclofenac; Drug Therapy, Combinatio | 2020 |
Effect and safety of intravenous versus oral acetaminophen after unicompartmental knee replacement: A protocol of randomized controlled study.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Opioid; Arthroplasty, | 2020 |
Effects of preemptive analgesia with intravenous acetaminophen on postoperative pain relief in patients undergoing third molar surgery: a prospective, single-blind, randomized controlled trial.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Humans; | 2021 |
Effect of Acetaminophen on Postoperative Percocet Use In Hip Arthroscopy: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Arthroscopy; Female; Femoracetabular Impingement; Hip; Hum | 2021 |
Comparison of analgesic efficacy of acetaminophen monotherapy versus acetaminophen combinations with either pethidine or parecoxib in patients undergoing laparoscopic cholecystectomy: a randomized prospective study.
Topics: Acetaminophen; Analgesics; Cholecystectomy, Laparoscopic; Double-Blind Method; Humans; Isoxazoles; M | 2021 |
Comparison of Monotherapy Versus Combination of Intravenous Ibuprofen and Propacetamol (Acetaminophen) for Reduction of Postoperative Opioid Administration in Children Undergoing Laparoscopic Hernia Repair: A Double-Blind Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroi | 2021 |
Preoperative Intravenous Versus Oral Acetaminophen in Outpatient Surgery: A Double-Blinded, Randomized Control Trial.
Topics: Acetaminophen; Administration, Intravenous; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic | 2021 |
Comparison of 3 protocols for analgesia control after cesarean delivery: a randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesia; Analgesics; Anal | 2019 |
A Multimodal Pain Management Regimen for Open Treatment of Distal Radius Fractures: A Randomized Blinded Study.
Topics: Acetaminophen; Analgesics, Opioid; Celecoxib; Humans; Narcotics; Oxycodone; Pain Management; Pain, P | 2022 |
Can Acetaminophen Pretreatment Decrease the Pain Associated With Closed Nasal Bone Reduction? A Triple-Blind Randomized Clinical Trial.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Double-Blind Method; Humans; Male; Nasal Bone; P | 2021 |
The analgesic efficacy of ultrasound-guided transversus abdominis plane (TAP) block combined with oral multimodal analgesia in comparison with oral multimodal analgesia after caesarean delivery: a randomized controlled trial.
Topics: Abdominal Muscles; Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesics; C | 2021 |
Diclofenac Is Superior to Paracetamol in Postoperative Pain Scores and Analgesic Consumption in Supratentorial Craniotomy With No Difference in Platelet and Clot Function: A Prospective Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Crani | 2022 |
Effect of perioperative acetaminophen on pain management in patients undergoing rotator cuff repair: a prospective randomized study.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Humans; Middle Aged; Pain Management; Pain, Postoperative; | 2021 |
Efficacy of Intravenous Paracetamol and Ibuprofen on Postoperative Pain and Morphine Consumption in Lumbar Disc Surgery: Prospective, Randomized, Double-Blind, Placebo-Controlled Clinical Trial.
Topics: Acetaminophen; Humans; Ibuprofen; Morphine; Pain Measurement; Pain, Postoperative; Prospective Studi | 2021 |
The intraperitoneal ondansetron for postoperative pain management following laparoscopic cholecystectomy: A proof-of-concept, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Adult; Analgesics; Antiemetics; Cholecystectomy, Laparoscopi | 2021 |
Effect of intravenous dexamethasone on postoperative pain and swelling following periodontal flap surgery: A randomized controlled trial of patient-centered outcomes.
Topics: Acetaminophen; Analgesics; Dexamethasone; Double-Blind Method; Humans; Ibuprofen; Pain, Postoperativ | 2022 |
Prophylactic administration of diphenhydramine/paracetamol reduced emergence agitation and postoperative pain following maxillofacial surgeries: a randomized controlled trial.
Topics: Acetaminophen; Adult; Anesthesia Recovery Period; Anesthesia, General; Dexmedetomidine; Diphenhydram | 2022 |
Comparison of preemptive ibuprofen, acetaminophen, and placebo administration in reducing peri- and postoperative pain in primary tooth extraction: A randomized clinical trial.
Topics: Acetaminophen; Child; Double-Blind Method; Humans; Ibuprofen; Pain, Postoperative; Tooth, Deciduous | 2021 |
The erector spinae plane block can facilitate outpatient stone surgery by reducing breakthrough pain.
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Op | 2021 |
The effect of scalp block or local wound infiltration versus systemic analgesia on post-craniotomy pain relief.
Topics: Acetaminophen; Adult; Analgesia; Anesthetics, Local; Craniotomy; Double-Blind Method; Humans; Pain, | 2022 |
Oxycodone-paracetamol tablet exhibits increased analgesic efficacy for acute postoperative pain, higher satisfaction and comparable safety profiles compared with celecoxib in patients underwent arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Ag | 2021 |
Educational Video on Pain Management and Subsequent Opioid Use After Cesarean Delivery: A Randomized Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Cesarean Section; Female; Humans; Ibuprofen; Opioid-Relate | 2021 |
Extending the safety profile of the post-operative administration of an intravenous acetaminophen/ibuprofen fixed dose combination: An open-label, multi-center, single arm, multiple dose study.
Topics: Acetaminophen; Acute Pain; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, | 2021 |
Postoperative pain treatment with transmuscular quadratus lumborum block and fascia iliaca compartment block in patients undergoing total hip arthroplasty: a randomized controlled trial.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, Hip; Fema | 2021 |
Comparison of Oral Loading Dose to Intravenous Acetaminophen in Children for Analgesia After Tonsillectomy and Adenoidectomy: A Randomized Clinical Trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Intravenous; Administration, Oral; Adolescent; Analges | 2021 |
Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial.
Topics: Acetaminophen; Antiemetics; Diphenhydramine; Double-Blind Method; Gastrectomy; Humans; Laparoscopy; | 2021 |
The effect of PECS-1 block on postoperative pain in total implantable venous access port catheter (TIVAP) insertion.
Topics: Acetaminophen; Bupivacaine; Catheterization, Central Venous; Catheters; Humans; Nerve Block; Pain, P | 2023 |
Assessment of Opioid Use and Analgesic Requirements After Endoscopic Sinus Surgery: A Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2021 |
Participants with mild, moderate, or severe pain following total hip arthroplasty. A sub-study of the PANSAID trial on paracetamol and ibuprofen for postoperative pain treatment.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Hip; Humans; Ibuprofen; Pain, Po | 2021 |
Efficacy of Preoperative Administration of Paracetamol-Codeine on Pain following Impacted Mandibular Third Molar Surgery: A Randomized, Split-Mouth, Placebo-Controlled, Double-Blind Clinical Trial.
Topics: Acetaminophen; Adult; Analgesics; Codeine; Cohort Studies; Double-Blind Method; Drug Administration | 2017 |
The effect of nefopam on lactation after caesarean section: a single-blind randomised trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Obstetrical; Anesthesia, Spinal; Body We | 2017 |
Randomized controlled trial of intravenous acetaminophen for postcesarean delivery pain control.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Double-Blind M | 2017 |
Efficacy of Intravenous Acetaminophen in Periimplantation Pain of Cardiac Electronic Devices: A Randomized Double-Blinded Study.
Topics: Acetaminophen; Double-Blind Method; Female; Humans; Male; Pain Measurement; Pain, Postoperative; Pro | 2017 |
The analgesic effects of rectal diclofenac versus rectal paracetamol following caudal-bupivacaine for pediatric day-case inguinal herniotomies: a randomized controlled prospective trial.
Topics: Acetaminophen; Administration, Rectal; Analgesia; Analgesics; Anesthesia, Caudal; Child; Child, Pres | 2017 |
Analgesic Effects of Intravenous Acetaminophen vs Placebo for Endoscopic Sinus Surgery and Postoperative Pain: A Randomized Clinical Trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Double-Blind Method; Endoscopy; Female; Humans; Infusions, | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Decreasing postoperative narcotics in reconstructive pelvic surgery: a randomized controlled trial.
Topics: Acetaminophen; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Celecoxib; Cyclohexanecarboxylic | 2017 |
Intravenous Acetaminophen in Multimodal Pain Management for Patients Undergoing Total Knee Arthroplasty: A Randomized, Double-Blind, Placebo-Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti- | 2017 |
Efficacy of Codeine When Added to Paracetamol (Acetaminophen) and Ibuprofen for Relief of Postoperative Pain After Surgical Removal of Impacted Third Molars: A Double-Blinded Randomized Control Trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blind Method; Drug Ther | 2017 |
The effect of ondansetron on analgesic efficacy of acetaminophen after hysterectomy: A randomized double blinded placebo controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Double-Blind Method | 2017 |
Intravenous vs Oral Acetaminophen as an Adjunct to Multimodal Analgesia After Total Knee Arthroplasty: A Prospective, Randomized, Double-Blind Clinical Trial.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Aged; Analgesia, Patient-Controlle | 2017 |
Transcutaneous electrical nerve stimulation for postoperative pain relief after arthroscopic rotator cuff repair: a prospective double-blinded randomized trial.
Topics: Acetaminophen; Adult; Aged; Arthroscopy; Double-Blind Method; Drug Combinations; Female; Humans; Mal | 2017 |
Administering of pregabalin and acetaminophen on management of postoperative pain in patients with nasal polyposis undergoing functional endoscopic sinus surgery.
Topics: Acetaminophen; Adult; Analgesics; Double-Blind Method; Female; Humans; Male; Middle Aged; Nasal Poly | 2017 |
Codeine Plus Acetaminophen for Pain After Photorefractive Keratectomy: A Randomized, Double-Blind, Placebo-Controlled Add-On Trial.
Topics: Acetaminophen; Administration, Oral; Adult; Astigmatism; Codeine; Double-Blind Method; Drug Combinat | 2017 |
Randomized Prospective Evaluation of Intraoperative Intravenous Acetaminophen in Pediatric Adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; | 2018 |
Wound infiltration with bupivacaine 0.5% with or without adrenaline does not decrease pain after thyroidectomy. A randomized controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2017 |
Effects of Addition of Preoperative Intravenous Ibuprofen to Pregabalin on Postoperative Pain in Posterior Lumbar Interbody Fusion Surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; | 2017 |
Comparison between Lornoxicam and Paracetamol for Pain Management after Dilation and Curettage for Abortion.
Topics: Abortion, Induced; Acetaminophen; Dilatation and Curettage; Female; Humans; Pain, Postoperative; Pai | 2017 |
Combined intraoperative paracetamol and preoperative dexamethasone reduces postoperative sore throat: a prospective randomized study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Anesthesia, General; Dexamethasone; Doubl | 2017 |
PANSAID-PAracetamol and NSAID in combination: detailed statistical analysis plan for a randomised, blinded, parallel, four-group multicentre clinical trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2017 |
Postoperative Intravenous Acetaminophen for Craniotomy Patients: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioi | 2018 |
Intravenous Acetaminophen Does Not Decrease Persistent Surgical Pain After Cardiac Surgery.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Non-Narcotic; Cardiac Surgical Procedu | 2017 |
Periprocedural analgesic efficacy of a single, pre-emptive administration of propacetamol in catheter ablation for atrial fibrillation: a randomized controlled trial.
Topics: Acetaminophen; Analgesics; Atrial Fibrillation; Catheter Ablation; Double-Blind Method; Female; Huma | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Scheduled Intravenous Acetaminophen Improves Patient Satisfaction With Postcraniotomy Pain Management: A Prospective, Randomized, Placebo-controlled, Double-blind Study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Craniotomy; Double-Blind Metho | 2018 |
Pain Relief After Operative Treatment of an Extremity Fracture: A Noninferiority Randomized Controlled Trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2017 |
Single dose systemic acetaminophen to improve patient reported quality of recovery after ambulatory segmental mastectomy: A prospective, randomized, double-blinded, placebo controlled, clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Na | 2018 |
Preoperative cesarean delivery intravenous acetaminophen treatment for postoperative pain control: a randomized double-blinded placebo control trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Ces | 2018 |
Demonstration of analgesic effect of intranasal ketamine and intranasal fentanyl for postoperative pain after pediatric tonsillectomy.
Topics: Acetaminophen; Administration, Intranasal; Administration, Intravenous; Adolescent; Analgesics; Chil | 2018 |
Does Intravenous Acetaminophen Improve Postoperative Pain Control after Laparoscopic Appendectomy for Perforated Appendicitis? A Prospective Randomized Trial.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narc | 2019 |
The Effects of Apotel and Remifentanil on Postoperative Pain.
Topics: Acetaminophen; Analgesics, Opioid; Anesthetics, Intravenous; Cesarean Section; Female; Humans; Iran; | 2019 |
Decreased opioid consumption and enhance recovery with the addition of IV Acetaminophen in colorectal patients: a prospective, multi-institutional, randomized, double-blinded, placebo-controlled study (DOCIVA study).
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Colecto | 2018 |
Effect of intravenous preoperative versus postoperative paracetamol on postoperative nausea and vomiting in patients undergoing strabismus surgery: A prospective randomized study.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Child; Child, Preschool; Drug Administration | 2018 |
Analgesic Effect - Comparison of Paracetamol Administered Intermittently and Through Patient-Controlled Analgesia Pump after Lumbar Discectomy: a Prospective Clinical Study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics | 2017 |
Comparing the Efficacy of Peritonsillar Injection of Tramadol With Honey in Controlling Post-Tonsillectomy Pain in Adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Opioid; Anti-Bacterial Agents; Child; Combined Modalit | 2018 |
Randomized trial of oral versus intravenous acetaminophen for postoperative pain control.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Aged; Analgesics, Non-Narcotic; An | 2018 |
Use of Intravenous Acetaminophen in Postoperative Pain Management After Partial and Full Bony Impacted Third Molar Extractions: A Randomized Double-Blind Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesics, Non-Narcotic; Double-Blin | 2018 |
Grommet and adenoid pain evaluation (GRAPE) study.
Topics: Acetaminophen; Adenoidectomy; Adenoids; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; H | 2018 |
Effectiveness of Novel Adjuncts in Pain Management Following Total Knee Arthroplasty: A Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Opioid; Anesthetics, Local; Arthroplas | 2018 |
Effectiveness of Novel Adjuncts in Pain Management Following Total Knee Arthroplasty: A Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Opioid; Anesthetics, Local; Arthroplas | 2018 |
Effectiveness of Novel Adjuncts in Pain Management Following Total Knee Arthroplasty: A Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Opioid; Anesthetics, Local; Arthroplas | 2018 |
Effectiveness of Novel Adjuncts in Pain Management Following Total Knee Arthroplasty: A Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Opioid; Anesthetics, Local; Arthroplas | 2018 |
Intravenous acetaminophen for postoperative supratentorial craniotomy pain: a prospective, randomized, double-blinded, placebo-controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniotomy | 2018 |
Preemptive Analgesia Decreases Pain Following Anorectal Surgery: A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Anal Canal; Analgesics; Analgesics, Op | 2018 |
The analgesic efficacy and pharmacokinetics of epidural oxycodone after gynaecological laparotomy: a randomized, double-blind, double-dummy comparison with intravenous administration.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia, Epidural; Analgesics, Opioid; Dose-Res | 2018 |
Opioid Use following Outpatient Breast Surgery: Are Physicians Part of the Problem?
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Drug Combinations; D | 2018 |
Comparison of intravenous ibuprofen and acetaminophen for postoperative multimodal pain management in bariatric surgery: A randomized controlled trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid | 2018 |
A Randomized, Double-Blind, Placebo-Controlled Trial of Intravenous Acetaminophen on Hospital Length of Stay in Obese Individuals Undergoing Sleeve Gastrectomy.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Double-Blind Method; Gastrecto | 2018 |
Multi-Modal Pain Control in Ambulatory Hand Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combi | 2018 |
Do children undergoing bilateral myringotomy with placement of ventilating tubes benefit from pre-operative analgesia? A double-blinded, randomised, placebo-controlled trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2018 |
The comparison of single-dose preemptive intravenous ibuprofen and paracetamol on postoperative pain scores and opioid consumption after open septorhinoplasty: a randomized controlled study.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia, Patient-Controlled; Analgesics; Analge | 2018 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
Bilateral Erector Spinae Plane Block for Acute Post-Surgical Pain in Adult Cardiac Surgical Patients: A Randomized Controlled Trial.
Topics: Abdominal Muscles; Acetaminophen; Acute Pain; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics | 2019 |
A randomized controlled trial of postoperative intravenous acetaminophen plus thoracic epidural analgesia vs. thoracic epidural analgesia alone after gastrectomy for gastric cancer.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Fem | 2019 |
The analgesic efficiency of transversus abdominis plane (TAP) block after caesarean delivery.
Topics: Abdominal Muscles; Acetaminophen; Administration, Intravenous; Analgesia, Obstetrical; Analgesia, Pa | 2018 |
Analgesic Efficacy of an Acetaminophen/Ibuprofen Fixed-dose Combination in Moderate to Severe Postoperative Dental Pain: A Randomized, Double-blind, Parallel-group, Placebo-controlled Trial.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Analgesics; Double-Blind Method; Drug Combinations; Fe | 2018 |
Pain Management After Carpal Tunnel Release Surgery: A Prospective Randomized Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2018 |
Effectiveness of acetaminophen in control of breakthrough pain: Randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Breakthrough Pa | 2018 |
Does Pre-Emptive Administration of Intravenous Ibuprofen (Caldolor) or Intravenous Acetaminophen (Ofirmev) Reduce Postoperative Pain and Subsequent Narcotic Consumption After Third Molar Surgery?
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Bli | 2019 |
Acetaminophen reduces acute and persistent incisional pain after hysterectomy.
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Chronic Pain; Female; Humans; Hysterectomy; Pai | 2018 |
A prospective randomized study to analyze the efficacy of balanced pre-emptive analgesia in spine surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anti-Anxiety Agents; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
[Comparative study of the effect of two analgesic techniques in postoperative pain control in pediatric surgery].
Topics: Abdomen; Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anti-Inflamm | 2018 |
Analgesic effectiveness, pharmacokinetics, and safety of a paracetamol/ibuprofen fixed-dose combination in children undergoing adenotonsillectomy: A randomized, single-blind, parallel group trial.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Child, Preschool; Drug Therapy, Combi | 2018 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
Comparison of Intravenous Ibuprofen and Paracetamol for Postoperative Pain Management after Laparoscopic Sleeve Gastrectomy. A Randomized Controlled Study.
Topics: Acetaminophen; Administration, Intravenous; Bariatric Surgery; Gastrectomy; Humans; Ibuprofen; Lapar | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
A Prospective, Randomized, Double-Blinded Controlled Trial Comparing Ibuprofen and Acetaminophen Versus Hydrocodone and Acetaminophen for Soft Tissue Hand Procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opi | 2019 |
Intravenous vs Oral Acetaminophen for Analgesia After Cesarean Delivery: A Randomized Trial.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesics, Non-Narcotic; A | 2019 |
A comparative study on the prophylactic effects of paracetamol and dexmedetomidine for controlling hemodynamics during surgery and postoperative pain in patients with laparoscopic cholecystectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Blood Pressure; Cholecystectomy, L | 2018 |
Analgesic efficacy of ketorolac associated with a tramadol/acetaminophen combination after third molar surgery - a randomized, triple-blind clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infl | 2019 |
Prevention of Opioid-Induced Nausea and Vomiting During Treatment of Moderate to Severe Acute Pain: A Randomized Placebo-Controlled Trial Comparing CL-108 (Hydrocodone 7.5 mg/Acetaminophen 325 mg/Rapid-Release, Low-Dose Promethazine 12.5 mg) with Conventi
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Analgesics, Opioid; Antiemetics; Drug Combinations; Fe | 2019 |
Intravenous acetaminophen vs saline in perioperative analgesia with laparoscopic hysterectomy.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dou | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Intravenous Acetaminophen Before Pelvic Organ Prolapse Repair: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analg | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Effect of Combination of Paracetamol (Acetaminophen) and Ibuprofen vs Either Alone on Patient-Controlled Morphine Consumption in the First 24 Hours After Total Hip Arthroplasty: The PANSAID Randomized Clinical Trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplast | 2019 |
Is interferential current effective in the management of pain, range of motion, and edema following total knee arthroplasty surgery? A randomized double-blind controlled trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Knee; Double-Blind Method; | 2019 |
Tramadol/dexketoprofen (TRAM/DKP) compared with tramadol/paracetamol in moderate to severe acute pain: results of a randomised, double-blind, placebo and active-controlled, parallel group trial in the impacted third molar extraction pain model (DAVID stud
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Drug Therapy, Combi | 2019 |
Effect of Topical Baclofen 5% on Post-Hemorrhoidectomy Pain: Randomized Double Blind Placebo-Controlled Clinical Trial.
Topics: Acetaminophen; Administration, Topical; Adult; Analgesics; Baclofen; Double-Blind Method; Female; GA | 2020 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
A Prospective, Randomized, Double-Blinded Trial Comparing Acetaminophen, Ibuprofen, and Oxycodone for Pain Management After Hand Surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Carpal | 2019 |
Multimodal Pain Management for Cesarean Delivery: A Double-Blinded, Placebo-Controlled, Randomized Clinical Trial.
Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthet | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
A Randomized Single-Blinded Trial of Ibuprofen- versus Opioid-Based Primary Analgesic Therapy in Outpatient Otolaryngology Surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2019 |
Evaluating the Effect of Intravenous Acetaminophen in Multimodal Analgesia After Total Hip Arthroplasty: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, N | 2019 |
Comparison of the postoperative analgesic efficacies of intravenous acetaminophen and fascia iliaca compartment block in hip fracture surgery: A randomised controlled trial.
Topics: Acetaminophen; Aged, 80 and over; Analgesics; Arthroplasty, Replacement, Hip; Fascia; Female; Femora | 2019 |
Multicentre, prospective, double-blind, randomised controlled clinical trial comparing different non-opioid analgesic combinations with morphine for postoperative analgesia: the OCTOPUS study.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Do | 2019 |
Intravenous Paracetamol in Adjunct to Intravenous Ketoprofen for Postoperative Pain in Children Undergoing General Surgery: A Double-Blinded Randomized Study.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Comparison of Ibuprofen vs Acetaminophen and Severe Bleeding Risk After Pediatric Tonsillectomy: A Noninferiority Randomized Clinical Trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method; F | 2019 |
Metamizole vs. ibuprofen at home after day case surgery: A double-blind randomised controlled noninferiority trial.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics, | 2019 |
Intravenous vs Oral Acetaminophen as a Component of Multimodal Analgesia After Total Hip Arthroplasty: A Randomized, Blinded Trial.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesia; Analgesics, Opioid; Arthroplasty | 2019 |
A Randomized, Placebo-Controlled, Double-Blind Study that Evaluates Efficacy of Intravenous Ibuprofen and Acetaminophen for Postoperative Pain Treatment Following Laparoscopic Cholecystectomy Surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Double-B | 2020 |
Pain Management After Surgical Tonsillectomy: Is There a Favorable Analgesic?
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Child; Female; Humans; I | 2019 |
Peritonsillar dexamethasone-bupivacaine vs. bupivacaine infiltration for post-tonsillectomy pain relief in children: a randomized, double-blind, controlled study.
Topics: Acetaminophen; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; Dexamethasone; Double-Blind | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Adductor canal block versus local infiltration analgesia for postoperative pain after anterior cruciate ligament reconstruction: a single centre randomised controlled triple-blinded trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior | 2019 |
Bilateral subcostal transversus abdominis plane block does not improve the postoperative analgesia provided by multimodal analgesia after laparoscopic cholecystectomy: A randomised placebo-controlled trial.
Topics: Abdominal Muscles; Acetaminophen; Adult; Aged; Analgesia; Analgesics, Opioid; Anesthetics; Cholecyst | 2019 |
Multimodal opioid-sparing postoperative pain regimen compared with the standard postoperative pain regimen in vaginal pelvic reconstructive surgery: a multicenter randomized controlled trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Postoperative pain and bleeding after adenotonsillectomy versus adenotonsillotomy in pediatric obstructive sleep apnea: an RCT.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method | 2019 |
Postoperative pain and bleeding after adenotonsillectomy versus adenotonsillotomy in pediatric obstructive sleep apnea: an RCT.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method | 2019 |
Postoperative pain and bleeding after adenotonsillectomy versus adenotonsillotomy in pediatric obstructive sleep apnea: an RCT.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method | 2019 |
Postoperative pain and bleeding after adenotonsillectomy versus adenotonsillotomy in pediatric obstructive sleep apnea: an RCT.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind Method | 2019 |
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, K | 2013 |
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, K | 2013 |
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, K | 2013 |
Gabapentin does not improve multimodal analgesia outcomes for total knee arthroplasty: a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia, Patient-Controlled; Analgesics; Arthroplasty, Replacement, K | 2013 |
Pre-emptive triple analgesia protocol for tonsillectomy pain control in children: double-blind, randomised, controlled, clinical trial.
Topics: Acetaminophen; Anesthetics, Local; Child; Child, Preschool; Diclofenac; Double-Blind Method; Female; | 2013 |
Comparison of the efficacy and safety of dual-opioid treatment with morphine plus oxycodone versus oxycodone/acetaminophen for moderate to severe acute pain after total knee arthroplasty.
Topics: Acetaminophen; Aged; Algorithms; Drug Therapy, Combination; Female; Humans; Male; Middle Aged; Morph | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Effect of preemptive and preventive acetaminophen on postoperative pain score: a randomized, double-blind trial of patients undergoing lower extremity surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Double | 2013 |
Efficacy of extended-release oral diclofenac in postoperative pain management after photorefractive keratectomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Astigmatism | 2013 |
Morphine-sparing effect of intravenous paracetamol for post operative pain management following gynaecological surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Drug Therapy, Combination; Female; Gynecologic S | 2012 |
Morphine-sparing effect of intravenous paracetamol for post operative pain management following gynaecological surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Drug Therapy, Combination; Female; Gynecologic S | 2012 |
Morphine-sparing effect of intravenous paracetamol for post operative pain management following gynaecological surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Drug Therapy, Combination; Female; Gynecologic S | 2012 |
Morphine-sparing effect of intravenous paracetamol for post operative pain management following gynaecological surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Drug Therapy, Combination; Female; Gynecologic S | 2012 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
A comprehensive multimodal pain treatment reduces opioid consumption after multilevel spine surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics, Non-Narcotic; Analges | 2013 |
The importance of communication in the management of postoperative pain.
Topics: Acetaminophen; Adult; Amines; Analgesics; Analgesics, Opioid; Celecoxib; Communication; Cyclohexanec | 2013 |
Epidural versus continuous transversus abdominis plane catheter technique for postoperative analgesia after abdominal surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, | 2013 |
Postoperative fentanyl patch versus subacromial bupivacaine infusion in arthroscopic shoulder surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Bupiva | 2013 |
Patient education videos for elective colorectal surgery: results of a randomized controlled trial.
Topics: Acetaminophen; Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-St | 2013 |
A randomized controlled trial of the effectiveness of educating parents about distraction to decrease postoperative pain in children at home after tonsillectomy.
Topics: Acetaminophen; Child; Child Behavior; Child, Preschool; Female; Follow-Up Studies; Humans; Iceland; | 2014 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Evaluation of the effect of aromatherapy with lavender essential oil on post-tonsillectomy pain in pediatric patients: a randomized controlled trial.
Topics: Acetaminophen; Aromatherapy; Child; Female; Follow-Up Studies; Humans; Lavandula; Male; Oils, Volati | 2013 |
Opioid-sparing effect of intravenous paracetamol after percutaneous nephrolithotomy: a double-blind randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Female; Hum | 2014 |
Efficacy and speed of onset of pain relief of fast-dissolving paracetamol on postsurgical dental pain: two randomized, single-dose, double-blind, placebo-controlled clinical studies.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2013 |
Efficacy and speed of onset of pain relief of fast-dissolving paracetamol on postsurgical dental pain: two randomized, single-dose, double-blind, placebo-controlled clinical studies.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2013 |
Efficacy and speed of onset of pain relief of fast-dissolving paracetamol on postsurgical dental pain: two randomized, single-dose, double-blind, placebo-controlled clinical studies.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2013 |
Efficacy and speed of onset of pain relief of fast-dissolving paracetamol on postsurgical dental pain: two randomized, single-dose, double-blind, placebo-controlled clinical studies.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2013 |
Comparison of intravenous ketorolac with or without paracetamol in postoperative pain control following ambulatory surgery.
Topics: Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anti-Inf | 2013 |
Randomized comparison between the combination of acetaminophen and ibuprofen and each constituent alone for analgesia following tonsillectomy in children.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2013 |
Median effective dose (ED₅₀) of paracetamol and morphine for postoperative pain: a study of interaction.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Interactions; F | 2014 |
Comparative study of intravenous Tramadol versus Ketorolac for preventing postoperative pain after third molar surgery--a prospective randomized study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Ag | 2014 |
The postoperative analgesic effect of morphine and paracetamol in the patients undergoing laparotomy, using PCA method.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-B | 2013 |
Parecoxib and paracetamol for pain relief following minor day-stay gynaecological surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Cyclooxygenase 2 Inh | 2014 |
[Efficacy of intravenous dexketoprofen trometamol compared to intravenous paracetamol for postoperative pain management after day-case operative hysteroscopy: randomized, double-blind, placebo-controlled study].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; | 2014 |
Intravenous paracetamol as an antipyretic and analgesic medication: the significance of drug metabolism.
Topics: Abdominal Pain; Acetaminophen; Adolescent; Adult; Aged; Female; Fever; Humans; Infections; Infusions | 2014 |
Multimodal analgesia versus traditional opiate based analgesia after cardiac surgery, a randomized controlled trial.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; | 2014 |
Treatment of postoperative pain after total hip arthroplasty: comparison between metamizol and paracetamol as adjunctive to opioid analgesics-prospective, double-blind, randomised study.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non-Narcotic; Analgesics | 2014 |
Analgesic effectiveness of acetaminophen for primary cleft palate repair in young children: a randomized placebo controlled trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child, Preschool; Cleft Palate; Double-Blind Method; Female | 2014 |
Postoperative analgesia using diclofenac and acetaminophen in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Pres | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Dexamethasone for pain after outpatient shoulder surgery: a randomised, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Acromioclavicular Joint; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Validating speed of onset as a key component of good analgesic response in acute pain.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; | 2015 |
A comparison of pain scores and medication use in patients undergoing single-bundle or double-bundle anterior cruciate ligament reconstruction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior Cruciate Ligament; Ante | 2014 |
[Analgesia in hemophiliac patients during orthopedic surgery].
Topics: Acetaminophen; Adult; Analgesics; Arthroplasty, Replacement, Hip; Arthroplasty, Replacement, Knee; B | 2014 |
The addition of tramadol to the standard of i.v. acetaminophen and morphine infusion for postoperative analgesia in neonates offers no clinical benefit: a randomized placebo-controlled trial.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Synergism; Drug Therapy | 2014 |
Continuous wound infiltration with ropivacaine for analgesia after caesarean section: a randomised, placebo-controlled trial.
Topics: Abdominal Injuries; Acetaminophen; Adult; Amides; Analgesia; Anesthesia, Obstetrical; Anesthesia, Sp | 2014 |
Intermittent epidural vs continuous wound infusion of ropivacaine for acute and chronic pain control after hysterectomy or myomectomy: a randomized controlled trial.
Topics: Acetaminophen; Acute Pain; Adult; Amides; Analgesia, Epidural; Analgesics; Anesthetics, Local; Chron | 2014 |
Effect of low-dose dexketoprofen trometamol and paracetamol on postoperative complications after impacted third molar surgery on healthy volunteers: A pilot study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2014 |
Assessment of the safety and efficacy of extended-release oxycodone/acetaminophen, for 14 days postsurgery.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Analgesics, Opioid; Delayed-Action Preparations; | 2014 |
Analgesic interaction between ondansetron and acetaminophen after tonsillectomy in children: the Paratron randomized, controlled trial.
Topics: Acetaminophen; Adenoidectomy; Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2015 |
Efficacy of honey in reduction of post tonsillectomy pain, randomized clinical trial.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Bacterial Agents; Apitherapy; Child; Child | 2014 |
Pharmacokinetics of hydrocodone/acetaminophen combination product in children ages 6-17 with moderate to moderately severe postoperative pain.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Area Under Curve; Body Surface Area; Body Weight; Chi | 2015 |
Pre-emptive analgesia with pregabalin and celecoxib decreases postsurgical pain following maxillomandibular advancement surgery: a randomized controlled clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesia, Patient-Controlled; Analge | 2014 |
Effect of intraoperative analgesia on children's pain perception during recovery after painful dental procedures performed under general anaesthesia.
Topics: Acetaminophen; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, General; Anti-Inflammator | 2015 |
A randomized study to compare the efficacy and safety of extended-release and immediate-release tramadol HCl/acetaminophen in patients with acute pain following total knee replacement.
Topics: Acetaminophen; Acute Pain; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replace | 2015 |
Randomized, double-blind, placebo-controlled study to investigate the pharmacodynamic interaction of 5-HT3 antagonist ondansetron and paracetamol in postoperative patients operated in an ENT department under local anesthesia.
Topics: Acetaminophen; Analgesics; Anesthesia, Local; Double-Blind Method; Female; Humans; Male; Middle Aged | 2015 |
The effect of triple vs. double nonopioid therapy on postoperative pain and functional outcome after abdominal hysterectomy: a randomised double-blind control trial.
Topics: Acetaminophen; Adult; Amines; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclohexanecarboxyl | 2015 |
Effect of preoperative administration of intravenous paracetamol during cesarean surgery on hemodynamic variables relative to intubation, postoperative pain and neonatal apgar.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Ap | 2014 |
Opioid use in knee arthroplasty after receiving intravenous acetaminophen.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, | 2014 |
Acceptable effect of multimodal analgesic treatment after a Bascom cleft lift operation.
Topics: Acetaminophen; Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Antiemetics; Cyclohexaneca | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Morphine or Ibuprofen for post-tonsillectomy analgesia: a randomized trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Child; Child, Preschool; Dose-Response Relations | 2015 |
Randomized controlled trial of gabapentin as an adjunct to perioperative analgesia in total hip arthroplasty patients.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesia, Patient-Controlled; Analgesics; An | 2015 |
Combination paracetamol and ibuprofen for pain relief after oral surgery: a dose ranging study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2015 |
Randomized, double-blind, placebo-controlled study of the efficacy and safety of biphasic immediate-release/extended-release hydrocodone bitartrate/acetaminophen tablets for acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Delayed-Action Prepa | 2015 |
Comparison of the efficacy and safety of different doses of propacetamol for postoperative pain control after breast surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Analysis of Variance; Breast Neoplasms; D | 2015 |
[Preemptive local anesthetic infiltration in hallux valgus one-day surgery].
Topics: Acetaminophen; Ambulatory Surgical Procedures; Anesthesia, Local; Anesthetics, Local; Bupivacaine; H | 2015 |
Comparison of the analgesic effects of paracetamol and tramadol in lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics; Drug Monitoring; Female; Humans; Lumbar Vertebrae; Male; Middle Ag | 2015 |
Preoperative dexamethasone reduces acute but not sustained pain after lumbar disk surgery: a randomized, blinded, placebo-controlled trial.
Topics: Acetaminophen; Acute Pain; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammato | 2015 |
Pharmacokinetics of hydrocodone and tramadol administered for control of postoperative pain in dogs following tibial plateau leveling osteotomy.
Topics: Acetaminophen; Analgesics, Opioid; Animals; Area Under Curve; Dogs; Half-Life; Hydrocodone; Hydromor | 2015 |
Clinical efficacy of hydrocodone-acetaminophen and tramadol for control of postoperative pain in dogs following tibial plateau leveling osteotomy.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Animals; Anti-Inflammatory Agents, Non-Ste | 2015 |
Preemptive multimodal analgesia for postoperative pain management after lumbar fusion surgery: a randomized controlled trial.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Celecoxib; Delayed-Action Preparations; Drug Th | 2016 |
Comparison of the postoperative analgesic effects of paracetamol-codeine phosphate and naproxen sodium-codeine phosphate for lumbar disk surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Codeine; Female; Humans; Lumbar Vertebrae; Male; Middle Ag | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
Cesarean analgesia using levobupivacaine continuous wound infiltration: a randomized trial.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics | 2015 |
An Expedited Care Pathway with Ambulatory Brachial Plexus Analgesia Is a Cost-effective Alternative to Standard Inpatient Care after Complex Arthroscopic Elbow Surgery: A Randomized, Single-blinded Study.
Topics: Acetaminophen; Adult; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis | 2015 |
INTRAVENOUS DEXAMETHASONE IN COMBINATION WITH CAUDAL BLOCK PROLONGS POSTOPERATIVE ANALGESIA IN PEDIATRIC DAYCARE SURGERY.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Anesthesia, Caudal; Child; Child, Preschool; Dexameth | 2015 |
Preoperative Local Administration of Morphine as an Add-on Therapy in Patients Undergoing Surgical Removal of an Odontogenic Maxillary Cyst. A Randomized, Double-Blind Pilot Study.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Ane | 2015 |
Evaluation of a protocol-based intervention to promote timely switching from intravenous to oral paracetamol for post-operative pain management: an interrupted time series analysis.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Clinical Protocols; Drug Administration Routes; Drug Utiliz | 2015 |
A new analgesia regimen after (adeno) tonsillectomy in children: a pilot study.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Child; Child, Preschool; Drug Therapy, Combination; Female | 2016 |
Randomized trial of OFIRMEV versus placebo for pain management after laparoscopic sleeve gastrectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Bariatric Surge | 2016 |
Perioperative Continuous Ropivacaine Wound Infusion in Laparoscopic Cholecystectomy: A Randomized Controlled Double-blind Trial.
Topics: Acetaminophen; Adult; Aged; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2016 |
Tramadol-Paracetamol Combination for Postoperative Pain Relief in Elective Single-level Microdisectomy Surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Diskectomy; Double-Blind Method; | 2017 |
What is the Effect of No Endodontic Debridement on Postoperative Pain for Symptomatic Teeth with Pulpal Necrosis?
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Debridement | 2016 |
IV Acetaminophen Results in Lower Hospital Costs and Emergency Room Visits Following Bariatric Surgery: a Double-Blind, Prospective, Randomized Trial in a Single Accredited Bariatric Center.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Em | 2016 |
Does continuous wound infiltration enhance baseline intravenous multimodal analgesia after posterior spinal fusion surgery? A randomized, double-blinded, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics; Female; Humans; Male; Middle Aged; | 2017 |
Comparison of the analgesic effect of intravenous acetaminophen with that of flurbiprofen axetil on post-breast surgery pain: a randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Breas | 2016 |
Comparison of the effects of treatment with celecoxib, loxoprofen, and acetaminophen on postoperative acute pain after arthroscopic knee surgery: A randomized, parallel-group trial.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Non-Narcotic; Anterior Cruciate Ligament Injuries; Ant | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Double-blind Randomized Placebo-controlled Clinical Trial of Efficiency of Nonsteroidal Anti-inflammatory Drugs in the Control of Post-endodontic Pain.
Topics: Acetaminophen; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose- | 2016 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Postoperative pain after laparoscopic sleeve gastrectomy: comparison of three analgesic schemes (isolated intravenous analgesia, epidural analgesia associated with intravenous analgesia and port-sites infiltration with bupivacaine associated with intraven
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Anesthetics, Local; Bariatric S | 2017 |
Effect of intravenous vitamin C on postoperative pain in uvulopalatopharyngoplasty with tonsillectomy.
Topics: Acetaminophen; Adult; Analgesics; Antioxidants; Ascorbic Acid; Double-Blind Method; Female; Humans; | 2017 |
Effects of peroperative intravenous paracetamol and lornoxicam for lumbar disc surgery on postoperative pain and opioid consumption: A randomized, prospective, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Age | 2016 |
Intravenous acetaminophen analgesia after cardiac surgery: A randomized, blinded, controlled superiority trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; Double-Bli | 2016 |
Celecoxib Versus Placebo in Tonsillectomy: A Prospective, Randomized, Double-Blind Placebo-Controlled Trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Celecoxib; Chronic Disease; Cycl | 2016 |
Reduced anaesthetic requirements and postoperative analgesics in patients undergoing laparoscopic cholecystectomy: premedication with intravenous paracetamol versus ketorolac, a double blind and randomised clinical trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Inhalation; Anesthe | 2017 |
Duloxetine and Subacute Pain after Knee Arthroplasty when Added to a Multimodal Analgesic Regimen: A Randomized, Placebo-controlled, Triple-blinded Trial.
Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Anti-Inflammatory Agents, Non-Steroidal | 2016 |
Duloxetine and Subacute Pain after Knee Arthroplasty when Added to a Multimodal Analgesic Regimen: A Randomized, Placebo-controlled, Triple-blinded Trial.
Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Anti-Inflammatory Agents, Non-Steroidal | 2016 |
Duloxetine and Subacute Pain after Knee Arthroplasty when Added to a Multimodal Analgesic Regimen: A Randomized, Placebo-controlled, Triple-blinded Trial.
Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Anti-Inflammatory Agents, Non-Steroidal | 2016 |
Duloxetine and Subacute Pain after Knee Arthroplasty when Added to a Multimodal Analgesic Regimen: A Randomized, Placebo-controlled, Triple-blinded Trial.
Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Anti-Inflammatory Agents, Non-Steroidal | 2016 |
A Randomized Trial Comparing the Safety and Efficacy of Intravenous Ibuprofen versus Ibuprofen and Acetaminophen in Knee or Hip Arthroplasty.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, | 2016 |
COMPARISON OF THE EFFECTS OF PREEMPTIVE INTRAVENOUS AND RECTAL ACETAMINOPHEN ON PAIN MANAGEMENT AFTER INGUINAL HERNIORRHAPHY IN CHILDREN: A PLACEBO-CONTROLLED STUDY.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Child, Preschool; Double-Blind Meth | 2016 |
Transversus abdominis plane block after laparoscopic colonic resection in cancer patients: A randomised clinical trial.
Topics: Abdominal Muscles; Acetaminophen; Aged; Colectomy; Colonic Neoplasms; Denmark; Double-Blind Method; | 2016 |
Intravenous Acetaminophen as an Adjunct Analgesic in Cardiac Surgery Reduces Opioid Consumption But Not Opioid-Related Adverse Effects: A Randomized Controlled Trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Aged; Analgesia; Analgesics, Non-Narc | 2016 |
Tramadol hydrochloride/acetaminophen combination versus non-steroidal anti-inflammatory drug for the treatment of perioperative pain after total knee arthroplasty: A prospective, randomized, open-label clinical trial.
Topics: Acetaminophen; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Repla | 2016 |
Preoperative paracetamol improves post-cesarean delivery pain management: a prospective, randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthes | 2016 |
Periapical Microsurgery: The Effects of Locally Injected Dexamethasone on Pain, Swelling, Bruising, and Wound Healing.
Topics: Acetaminophen; Adrenal Cortex Hormones; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2016 |
Preemptive Analgesia in Hip Arthroscopy: A Randomized Controlled Trial of Preemptive Periacetabular or Intra-articular Bupivacaine in Addition to Postoperative Intra-articular Bupivacaine.
Topics: Acetaminophen; Adult; Anesthetics, Local; Arthroplasty, Replacement, Hip; Bupivacaine; Drug Combinat | 2017 |
Effects of Topical Atorvastatin (2 %) on Posthemorrhoidectomy Pain and Wound Healing: A Randomized Double-Blind Placebo-Controlled Clinical Trial.
Topics: Acetaminophen; Administration, Topical; Adult; Aged; Analgesics, Opioid; Atorvastatin; Defecation; D | 2017 |
Analgesic Effect of Perioperative Systemic Dexamethasone on Blowout Fracture Surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents; Dexamethasone; Female; Hum | 2017 |
[The effectiveness of preemptive analgesic techniques on postoperative analgesia in patients undergoing open septorhinoplasty].
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2016 |
Effect of a mixture of diosmin, coumarin glycosides, and triterpenes on bleeding, thrombosis, and pain after stapled anopexy: a prospective, randomized, placebo-controlled clinical trial.
Topics: Acetaminophen; Adult; Aged; Blood Loss, Surgical; Coumarins; Demography; Digestive System Surgical P | 2017 |
Randomized Prospective Trial Comparing the Use of Intravenous versus Oral Acetaminophen in Total Joint Arthroplasty.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Analgesi | 2017 |
Parecoxib, propacetamol, and their combination for analgesia after total hip arthroplasty: a randomized non-inferiority trial.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Arthroplasty, Replacem | 2017 |
The effect of IV dexamethasone versus local anesthetic infiltration technique in postoperative nausea and vomiting after tonsillectomy in children: A randomized double-blind clinical trial.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Anesthesia, Local; | 2017 |
A Preliminary Examination of the Comparative Efficacy of Intravenous vs Oral Acetaminophen in the Treatment of Perioperative Pain.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Analgesics, Non-Narcotic; C | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
PANSAID - PAracetamol and NSAID in combination: study protocol for a randomised trial.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Protocols; Drug Therapy, Combinatio | 2017 |
Is celecoxib a useful adjunct in the treatment of post-tonsillectomy pain in the adult population? A randomised, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Celecoxib; Cyclooxygenase 2 Inhibitors; Double-Blind M | 2017 |
The effect of tramadol plus paracetamol on consumption of morphine after coronary artery bypass grafting.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Co | 2017 |
Opioid-sparing effect of nefopam in combination with paracetamol after major abdominal surgery: a randomized double-blind study.
Topics: Abdomen; Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Dru | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Popliteal block for lower limb surgery in children with cerebral palsy: effect on sevoflurane consumption and postoperative pain (a randomized, double-blinded, controlled trial).
Topics: Acetaminophen; Adolescent; Anesthesia, General; Bupivacaine; Cerebral Palsy; Child; Child, Preschool | 2017 |
Fixed time interval compared with on-demand oral analgesia protocols for post-caesarean pain: a randomised controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesics; Cesarean Section; Di | 2017 |
Comparison of paracetamol, ibuprofen, and diclofenac potassium for pain relief following dental extractions and deep cavity preparations.
Topics: Acetaminophen; Adult; Anesthesia, Local; Anti-Inflammatory Agents, Non-Steroidal; Dental Cavity Prep | 2017 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Randomized, double-blinded, placebo-controlled trial comparing two multimodal opioid-minimizing pain management regimens following transsphenoidal surgery.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic | 2018 |
Ibuprofen versus acetaminophen for the relief of perineal pain after childbirth: a randomized controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Episiotomy; | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Intravenous paracetamol improves the quality of postoperative analgesia but does not decrease narcotic requirements.
Topics: Acetaminophen; Adult; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Blood Pres | 2008 |
Comparison of parecoxib and proparacetamol in endoscopic nasal surgery patients.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Double-Blind Method; Endo | 2008 |
[Does iv paracetamol have preemptive analgesic effect on lumber disc surgeries?].
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Diskectomy; Humans; Infusions, Intravenous; Inte | 2008 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pain management after tonsillectomy: morphine is not enough.
Topics: Acetaminophen; Adolescent; Algorithms; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioi | 2008 |
A randomized, double-blind, placebo-controlled study comparing the efficacy and safety of paracetamol, serratiopeptidase, ibuprofen and betamethasone using the dental impaction pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory | 2009 |
Efficacy of oral paracetamol and ketoprofen for pain management after major orthopedic surgery.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; | 2008 |
Onset of analgesia with sodium ibuprofen, ibuprofen acid incorporating poloxamer and acetaminophen--a single-dose, double-blind, placebo-controlled study in patients with post-operative dental pain.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Ibuprofen | 2009 |
Effects of combination treatment with ketoprofen 100 mg + acetaminophen 1000 mg on postoperative dental pain: a single-dose, 10-hour, randomized, double-blind, active- and placebo-controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 2009 |
Comparison of analgesic effect of tramadol alone and a combination of tramadol and paracetamol in day-care laparoscopic surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Blood Pressure; Doub | 2009 |
Analgesic efficacy of lysine clonixinate, paracetamol and dipyrone in lower third molar extraction: a randomized controlled trial.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Clonixin; Dipyrone; Female; Huma | 2009 |
[Postoperative analgesia after laparoscopic cholecystectomy: comparison of the preoperative administration of celecoxib with paracetamol?].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2008 |
The efficacy of acetaminophen-caffeine compared to Ibuprofen in the control of postoperative pain after periodontal surgery: a crossover pilot study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Caffeine; C | 2009 |
Paracetamol versus metamizol in the treatment of postoperative pain after breast surgery: a randomized, controlled trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2009 |
Preemptive analgesic effects of intravenous paracetamol in total abdominal hysterectomy.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Dose-Response Relationship, | 2009 |
Does 1 or 2 g paracetamol added to ketoprofen enhance analgesia in adult tonsillectomy patients?
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Anti-Inf | 2009 |
The prophylactic effect of rectal acetaminophen on postoperative pain and opioid requirements after adenotonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Analgesi | 2009 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Postoperative pain management with tramadol after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniot | 2010 |
Evaluation of intravenous paracetamol administration on postoperative pain and recovery characteristics in patients undergoing laparoscopic cholecystectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cholecystectomy, Laparoscopic; Humans; Infusions, Intraveno | 2009 |
[Assessment of quality in day-case hand surgery].
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Op | 2009 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
Multimodal analgesia with gabapentin, ketamine and dexamethasone in combination with paracetamol and ketorolac after hip arthroplasty: a preliminary study.
Topics: Acetaminophen; Aged; Amines; Analgesia; Analgesics; Arthroplasty, Replacement, Hip; Cyclohexanecarbo | 2010 |
A comparison of high volume/low concentration and low volume/high concentration ropivacaine in caudal analgesia for pediatric orchiopexy.
Topics: Acetaminophen; Administration, Oral; Ambulatory Surgical Procedures; Amides; Analgesics, Non-Narcoti | 2009 |
The analgesic effect of paracetamol when added to lidocaine for intravenous regional anesthesia.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recovery | 2009 |
Comparison of ibuprofen and acetaminophen with codeine following cosmetic facial surgery.
Topics: Acetaminophen; Analgesics; Codeine; Double-Blind Method; Drug Therapy, Combination; Face; Humans; Ib | 2009 |
Topical clindamycin in post-adenotonsillectomy analgesia in children: a double-blind, randomized clinical trial.
Topics: Acetaminophen; Adenoidectomy; Administration, Topical; Analgesia; Analgesics, Non-Narcotic; Anti-Bac | 2009 |
Clinical equivalence of controlled-release oxycodone 20 mg and controlled-release tramadol 200 mg after surgery for breast cancer.
Topics: Acetaminophen; Analgesics, Opioid; Breast Neoplasms; Delayed-Action Preparations; Double-Blind Metho | 2009 |
Dexamethasone decreases oxycodone consumption following osteotomy of the first metatarsal bone: a randomized controlled trial in day surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2010 |
A comparison of intra-articular magnesium and/or morphine with bupivacaine for postoperative analgesia after arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anesthetics, Local; Arthroscopy; Bupivacaine; Caffeine; Co | 2009 |
Diclofenac potassium liquid-filled soft gelatin capsules in the management of patients with postbunionectomy pain: a Phase III, multicenter, randomized, double-blind, placebo-controlled study conducted over 5 days.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; An | 2009 |
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana | 2009 |
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana | 2009 |
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana | 2009 |
The early and delayed analgesic effects of ketamine after total hip arthroplasty: a prospective, randomized, controlled, double-blind study.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Ana | 2009 |
The effect of a single dose of bupivacaine on donor site pain after anterior iliac crest bone harvesting.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Alveolar Ridge Augmentation; Analgesics, Non-Narcotic | 2010 |
Placebo-controlled trial of local anaesthesia for treatment of pain after breast reconstruction.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Anesthesia, Local; | 2009 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Combined acetaminophen and ibuprofen for pain relief after oral surgery in adults: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Drug Combinations; Female; Humans; Ibupr | 2010 |
Paracetamol reduces postoperative pain and rescue analgesic demand after robot-assisted endoscopic thyroidectomy by the transaxillary approach.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chi-Square Distribution; Double-Blind Method; Endosc | 2010 |
[Treating pain after dental surgery: a randomised, controlled, double-blind trial to assess a new formulation of paracetamol, opium powder and caffeine versus tramadol or placebo].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Caffeine; Central Nervous System Stimul | 2010 |
A randomized clinical trial of the efficacy of scheduled dosing of acetaminophen and hydrocodone for the management of postoperative pain in children after tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Child | 2010 |
Intraperitoneal lidocaine instillation and postcesarean pain after parietal peritoneal closure: a randomized double blind placebo-controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Cesarean Section; Double-Blind M | 2010 |
Antibiotic prophylaxis in third molar surgery: A randomized double-blind placebo-controlled clinical trial using split-mouth technique.
Topics: Acetaminophen; Adult; Amoxicillin; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Bacterial Agen | 2010 |
Brief report: improved pain relief using intermittent bupivacaine injections at the donor site after breast reconstruction with deep inferior epigastric perforator flap.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthetics, Local | 2010 |
Fentanyl sparing effects of combined ketorolac and acetaminophen for outpatient inguinal hernia repair in children.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Efficacy of intravenous paracetamol, metamizol and lornoxicam on postoperative pain and morphine consumption after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Double- | 2010 |
Intravenous paracetamol reduced the use of opioids, extubation time, and opioid-related adverse effects after major surgery in intensive care unit.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chemotherapy, Adjuvant; Female; H | 2010 |
Oral acetaminophen (paracetamol) for additional analgesia in phacoemulsification cataract surgery performed using topical anesthesia Randomized double-masked placebo-controlled trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesia; Analgesics, Non-Narcotic; Anesthesia, Local; A | 2010 |
[The effects of intravenous paracetamol on postoperative analgesia and tramadol consumption in cesarean operations].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
Preemptive effect of ketoprofen on postoperative pain following third molar surgery. A prospective, randomized, double-blinded clinical trial.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal | 2010 |
Preemptive dexamethasone and etoricoxib for pain and discomfort prevention after periodontal surgery: a double-masked, crossover, controlled clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Chronic Period | 2010 |
Is speech therapy useful as a complementary treatment for post-tonsillectomy pain?
Topics: Acetaminophen; Adolescent; Amoxicillin-Potassium Clavulanate Combination; Analgesics, Non-Narcotic; | 2010 |
Postoperative analgesia with parecoxib, acetaminophen, and the combination of both: a randomized, double-blind, placebo-controlled trial in patients undergoing thyroid surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics | 2010 |
Role of dexamethasone in reducing pain after endoscopic sinus surgery in adults: a double-blind prospective randomized trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Chronic Disease; Dexametha | 2010 |
The analgesic efficacy of subarachnoid morphine in comparison with ultrasound-guided transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesic | 2010 |
Acute pain after total hip arthroplasty does not predict the development of chronic postsurgical pain 6 months later.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Aged; Arthroplasty, Replacement, Hip; Celecoxib; Ch | 2010 |
Tramadol versus low dose tramadol-paracetamol for patient controlled analgesia during spinal vertebral surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Female; Humans; Male; M | 2010 |
Analgesic efficacy of topical tramadol in the control of postoperative pain in children after tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Topical; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2010 |
Effects of preemptive analgesia in laparoscopic cholecystectomy: a double-blind randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; | 2011 |
Postoperative analgesia in orthognathic surgery patients: diclofenac sodium or paracetamol?
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory | 2011 |
A single-tablet fixed-dose combination of racemic ibuprofen/paracetamol in the management of moderate to severe postoperative dental pain in adult and adolescent patients: a multicenter, two-stage, randomized, double-blind, parallel-group, placebo-control
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; | 2010 |
Comparison of efficacy and effectiveness between ULTRACET and tramadol/acetaminophen in acute postoperative pain after upper extremity surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Drug Combin | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Effect of dexamethasone in combination with caudal analgesia on postoperative pain control in day-case paediatric orchiopexy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2010 |
Comparison of the analgesic efficacy of concurrent ibuprofen and paracetamol with ibuprofen or paracetamol alone in the management of moderate to severe acute postoperative dental pain in adolescents and adults: a randomized, double-blind, placebo-control
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2010 |
Fentanyl-sparing effect of acetaminophen as a mixture of fentanyl in intravenous parent-/nurse-controlled analgesia after pediatric ureteroneocystostomy.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Child, Preschool; Cystostomy; Double-Blind Method; Dru | 2010 |
[Postoperative pain therapy after laparoscopic cholecystectomy: paracetamol versus diclofenac].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, L | 2010 |
Efficacy of intravenous paracetamol compared to dipyrone and parecoxib for postoperative pain management after minor-to-intermediate surgery: a randomised, double-blind trial.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anti-Inflammato | 2011 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal approach to postoperative pain control in patients undergoing rotator cuff repair.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Arthroscopy; Cyclooxygenase 2 | 2011 |
Two-agent analgesia versus acetaminophen in children having bilateral myringotomies and tubes surgery.
Topics: Acetaminophen; Administration, Intranasal; Administration, Rectal; Analgesics, Non-Narcotic; Analges | 2010 |
Efficacy of levobupivacaine infiltration to nephrosthomy tract in combination with intravenous paracetamol on postoperative analgesia in percutaneous nephrolithotomy patients.
Topics: Acetaminophen; Adult; Analgesia; Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Local; Bu | 2011 |
Rectal acetaminophen versus peritonsillar infiltration of bupivacaine for postoperative analgesia after adenotonsillectomy in children.
Topics: Acetaminophen; Acute Disease; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Anesthes | 2011 |
Comparison of oral versus sublingual piroxicam during postoperative pain management after lower third molar extraction.
Topics: Acetaminophen; Administration, Oral; Administration, Sublingual; Analgesics, Non-Narcotic; Anti-Infl | 2011 |
Comparison of peritonsillar levobupivacaine and bupivacaine infiltration for post-tonsillectomy pain relief in children: placebo-controlled clinical study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Drug Utilization; F | 2011 |
Evaluation of the dose range of etoricoxib in an acute pain setting using the postoperative dental pain model.
Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Dental; Anti-Inflammatory Agents, Non-Steroidal; Codei | 2011 |
The use of etoricoxib and celecoxib for pain prevention after periodontal surgery: a double-masked, parallel-group, placebo-controlled, randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Celecoxib; Chronic Periodontitis; Cycloo | 2011 |
Oral gabapentin for photorefractive keratectomy pain.
Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Astigmatism; Cyclohexanecarboxylic A | 2011 |
The use of a non-benzodiazepine hypnotic sleep-aid (Zolpidem) in patients undergoing ACL reconstruction: a randomized controlled clinical trial.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Analysis of Variance; Anterior Cruciate Ligament; Anti-Inf | 2011 |
Nicotine nasal spray as an adjuvant analgesic for third molar surgery.
Topics: Acetaminophen; Administration, Intranasal; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; | 2011 |
A randomised, five-parallel-group, placebo-controlled trial comparing the efficacy and tolerability of analgesic combinations including a novel single-tablet combination of ibuprofen/paracetamol for postoperative dental pain.
Topics: Acetaminophen; Adolescent; Analgesics; Dent Disease; Double-Blind Method; Drug Therapy, Combination; | 2011 |
Pregabalin and dexamethasone improves post-operative pain treatment after tonsillectomy.
Topics: Acetaminophen; Adult; Analgesics; Dexamethasone; Double-Blind Method; Drug Therapy, Combination; Fem | 2011 |
The efficacy of intravenous paracetamol versus tramadol for postoperative analgesia after adenotonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, | 2011 |
Intrathecal opioid versus ultrasound guided fascia iliaca plane block for analgesia after primary hip arthroplasty: study protocol for a randomised, blinded, noninferiority controlled trial.
Topics: Acetaminophen; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioi | 2011 |
Intrathecal opioid versus ultrasound guided fascia iliaca plane block for analgesia after primary hip arthroplasty: study protocol for a randomised, blinded, noninferiority controlled trial.
Topics: Acetaminophen; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioi | 2011 |
Intrathecal opioid versus ultrasound guided fascia iliaca plane block for analgesia after primary hip arthroplasty: study protocol for a randomised, blinded, noninferiority controlled trial.
Topics: Acetaminophen; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioi | 2011 |
Intrathecal opioid versus ultrasound guided fascia iliaca plane block for analgesia after primary hip arthroplasty: study protocol for a randomised, blinded, noninferiority controlled trial.
Topics: Acetaminophen; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioi | 2011 |
The effects of preoperative intravenous acetaminophen in patients undergoing abdominal hysterectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Femal | 2011 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
A randomized, double-blind, placebo-controlled, multicenter, repeat-dose study of two intravenous acetaminophen dosing regimens for the treatment of pain after abdominal laparoscopic surgery.
Topics: Abdomen; Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analge | 2010 |
Tropisetron and paracetamol association in post-operative patients.
Topics: Acetaminophen; Adult; Aged; Double-Blind Method; Female; Humans; Indoles; Male; Middle Aged; Otologi | 2012 |
Analgesia with paracetamol/tramadol vs. paracetamol/codeine in one day-surgery: a randomized open study.
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Codeine; Drug Therapy, Combin | 2011 |
Comparison of pre-emptive ibuprofen, paracetamol, and placebo administration in reducing post-operative pain in primary tooth extraction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
A randomized controlled trial comparing acetaminophen, acetaminophen and ibuprofen, and acetaminophen and codeine for postoperative pain relief after Mohs surgery and cutaneous reconstruction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Carcinoma, Basal Cel | 2011 |
[Tonsillotomy and adenotonsillectomy in childhood. Study on postoperative pain therapy].
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, | 2011 |
Efficiency of postoperative pain management after gynecologic oncological surgeries with the use of morphine + acetaminophen + ketoprofen versus morphine + metamizol + ketoprofen.
Topics: Acetaminophen; Analgesics; Carcinoma; Dipyrone; Drug Therapy, Combination; Endometrial Neoplasms; Fe | 2011 |
Target-controlled dosing of remifentanil during cardiac surgery reduces postoperative hyperalgesia.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Anesthesia, General; Anesthesia, Intravenous; Blood Pressur | 2011 |
Efficacy of augmenting a subacromial continuous-infusion pump with a preoperative interscalene block in outpatient arthroscopic shoulder surgery: a prospective, randomized, blinded, and placebo-controlled study.
Topics: Acetaminophen; Administration, Oral; Adult; Amides; Analgesics; Anesthetics, Local; Arthroscopy; Bra | 2011 |
Explaining the acetaminophen-ibuprofen analgesic interaction using a response surface model.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Child; Computer Simulation; Dose-Response Relationsh | 2011 |
Postoperative analgesia in impacted third molar surgery: the role of preoperative diclofenac sodium, paracetamol and lornoxicam.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non- | 2011 |
Improved recovery using multimodal perioperative analgesia in minimally invasive myomectomy: a randomised study.
Topics: Acetaminophen; Adult; Analgesics; Clinical Protocols; Diclofenac; Drug Therapy, Combination; Female; | 2011 |
A double-blind randomized crossover study to evaluate the timing of pregabalin for third molar surgery under local anesthesia.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Analge | 2012 |
A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy*.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; An | 2011 |
Effects of three oral analgesics on postoperative pain following root canal preparation: a controlled clinical trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C | 2012 |
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C | 2012 |
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C | 2012 |
Surgical outcome in children undergoing hypospadias repair under caudal epidural vs penile block.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Epidural; Blood Pressure; C | 2012 |
Effect of rectal diclofenac and acetaminophen alone and in combination on postoperative pain after cleft palate repair in children.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Stero | 2011 |
Evaluation of the muscle relaxant cyclobenzaprine after third-molar extraction.
Topics: Acetaminophen; Adolescent; Adult; Amitriptyline; Analgesics, Non-Narcotic; Double-Blind Method; Edem | 2011 |
Intravenous acetaminophen for pain after major orthopedic surgery: an expanded analysis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Female; Humans; Male; Middle Aged; Orthopedic | 2012 |
Comparison of three different analgesic protocols during shockwave lithotripsy.
Topics: Acetaminophen; Adult; Analgesia; Analgesics; Blood Pressure; Female; Heart Rate; Humans; Lithotripsy | 2012 |
Efficacy of Ibuprofen and ibuprofen/acetaminophen on postoperative pain in symptomatic patients with a pulpal diagnosis of necrosis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2011 |
Assessment of the efficacy and safety profiles of aspirin and acetaminophen with codeine: results from 2 randomized, controlled trials in individuals with tension-type headache and postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Va | 2012 |
Effect of single dose preoperative intramuscular dexamethasone injection on lower impacted third molar surgery.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents; Dexamethasone; Double-Blind Method; Edem | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
Multimodal analgesic treatment in video-assisted thoracic surgery lobectomy using an intraoperative intercostal catheter.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cath | 2012 |
The analgesic effect of continuous subacromial bupivacaine infusion after arthroscopic shoulder surgery: a randomized controlled trial.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Arthro | 2012 |
Comparison of efficacy of dexketoprofen versus paracetamol on postoperative pain and morphine consumption in laminectomy patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2011 |
[Comparison of the analgesic effects of intravenous paracetamol and lornoxicam in postoperative pain following thyroidectomies].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Ster | 2011 |
Comparative study of tramadol combined with dexamethasone and diclofenac sodium in third-molar surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: a double-blind randomised controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Arthroscopy; Double-Blin | 2012 |
Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: a double-blind randomised controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Arthroscopy; Double-Blin | 2012 |
Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: a double-blind randomised controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Arthroscopy; Double-Blin | 2012 |
Postoperative plasma paracetamol levels following oral or intravenous paracetamol administration: a double-blind randomised controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Non-Narcotic; Arthroscopy; Double-Blin | 2012 |
A descriptive feasibility study to evaluate scheduled oral analgesic dosing at home for the management of postoperative pain in preschool children following tonsillectomy.
Topics: Acetaminophen; Administration, Oral; Analgesics, Opioid; Caregivers; Child, Preschool; Drug Combinat | 2012 |
Pain relief after total hip replacement: oral CR oxycodone plus IV paracetamol versus epidural levobupivacaine and sufentanil. A randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics | 2012 |
Diclofenac-tramadol vs. diclofenac-acetaminophen combinations for pain relief after caesarean section.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Ag | 2012 |
Comparative analysis of preemptive analgesic effect of tramadol chlorhydrate and nimesulide following third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
Pregabalin and gabapentin for post-photorefractive keratectomy pain: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Codeine; Cyclohexanecarboxylic Acids | 2012 |
Intravenous lornoxicam is more effective than paracetamol as a supplemental analgesic after lower abdominal surgery: a randomized controlled trial.
Topics: Abdomen; Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Digestive System Sur | 2012 |
The efficacy of paracetamol versus tenoxicam on postoperative pain and morphine consumption after abdominal hysterectomy: a placebo-controlled, randomized study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2012 |
Acetaminophen improves analgesia but does not reduce opioid requirement after major spine surgery in children and adolescents.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid | 2012 |
A randomized, controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine (Tylenol 3) after outpatient breast surgery.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Breast Neoplasms; Ca | 2012 |
The analgesic concentration of oxycodone with co-administration of paracetamol -- a dose-finding study in adult patients undergoing laparoscopic cholecystectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Cholecystectomy, Laparoscopic; Dose-Response Relationship, D | 2012 |
Analgesic efficacy of tramadol/acetaminophen and propoxyphene/acetaminophen for relief of postoperative wound pain.
Topics: Acetaminophen; Adult; Aged; Analgesics; Dextropropoxyphene; Drug Combinations; Female; Humans; Male; | 2012 |
A randomized, double-blind, controlled trial on non-opioid analgesics and opioid consumption for postoperative pain relief after laparoscopic cholecystectomy.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Cholecyst | 2012 |
Comparison of post operative pain relief between paracetamol and wound infiltration with levobupivacaine in inguinal hernia repair.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; F | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Effect of adductor-canal-blockade on established, severe post-operative pain after total knee arthroplasty: a randomised study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 2012 |
Perioperative pregabalin for acute and chronic pain after abdominal hysterectomy or myomectomy: a randomised controlled trial.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics; Chronic Pain; Codeine; Double-Blind Method; Drug Combi | 2012 |
Comparison between systemic analgesia, continuous wound catheter analgesia and continuous thoracic paravertebral block: a randomised, controlled trial of postthoracotomy pain management.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2012 |
Comparison between systemic analgesia, continuous wound catheter analgesia and continuous thoracic paravertebral block: a randomised, controlled trial of postthoracotomy pain management.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2012 |
Comparison between systemic analgesia, continuous wound catheter analgesia and continuous thoracic paravertebral block: a randomised, controlled trial of postthoracotomy pain management.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2012 |
Comparison between systemic analgesia, continuous wound catheter analgesia and continuous thoracic paravertebral block: a randomised, controlled trial of postthoracotomy pain management.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; An | 2012 |
Intravesical ropivacaine as a novel means of analgesia post-robot-assisted radical prostatectomy: a randomized, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Administration, Intravesical; Aged; Amides; Analgesia; Anesthetics, Local; Double-Bli | 2013 |
Hydrocodone-acetaminophen for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2012 |
Hydrocodone-acetaminophen for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2012 |
Hydrocodone-acetaminophen for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2012 |
Hydrocodone-acetaminophen for pain control in first-trimester surgical abortion: a randomized controlled trial.
Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2012 |
Long-term quality of sleep after remifentanil-based anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Intravenous; Anesthetics, In | 2013 |
A randomized, double-blind, placebo-controlled study of acetaminophen 1000 mg versus acetaminophen 650 mg for the treatment of postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2012 |
A randomized, double-blind, placebo-controlled study of acetaminophen 1000 mg versus acetaminophen 650 mg for the treatment of postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2012 |
A randomized, double-blind, placebo-controlled study of acetaminophen 1000 mg versus acetaminophen 650 mg for the treatment of postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2012 |
A randomized, double-blind, placebo-controlled study of acetaminophen 1000 mg versus acetaminophen 650 mg for the treatment of postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Dose-Response Relationship, Drug; Double | 2012 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Oral vs intravenous paracetamol for lower third molar extractions under general anaesthesia: is oral administration inferior?
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Anesthesia, Genera | 2013 |
Median effective dose (ED50) of paracetamol and nefopam for postoperative pain: isobolographic analysis of their antinociceptive interaction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Dose-Response Relationship, Dru | 2013 |
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An | 2013 |
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An | 2013 |
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An | 2013 |
Ultrasound-guided transversus abdominal plane block with multimodal analgesia for pain management after total abdominal hysterectomy.
Topics: Abdominal Muscles; Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; An | 2013 |
Effect of intravenous paracetamol on postoperative morphine requirements in neonates and infants undergoing major noncardiac surgery: a randomized controlled trial.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind Method; Female; | 2013 |
A randomized evaluation of intravenous dexamethasone versus oral acetaminophen codeine in pediatric adenotonsillectomy: emergence agitation and analgesia.
Topics: Acetaminophen; Adenoidectomy; Administration, Intravenous; Administration, Oral; Analgesics, Non-Nar | 2012 |
Efficacy of three IV non-opioid-analgesics on opioid consumption for postoperative pain relief after total thyroidectomy: a randomised, double-blind trial.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2012 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
Efficacy of intravenous paracetamol and dexketoprofen on postoperative pain and morphine consumption after a lumbar disk surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opi | 2013 |
A double-blind, single-dose comparison of the analgesic efficacy of tramadol/acetaminophen combination tablets, hydrocodone/acetaminophen combination tablets, and placebo after oral surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Bl | 2002 |
Intravesical morphine analgesia is not effective after bladder surgery in children: results of a randomied double-blind study.
Topics: Acetaminophen; Administration, Intravesical; Adolescent; Child; Child, Preschool; Double-Blind Metho | 2002 |
Paracetamol versus paracetamol-codeine in the treatment of post-operative dental pain: a randomized, double-blind, prospective trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2002 |
Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Coronary Artery By | 2002 |
Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Coronary Artery By | 2002 |
Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Coronary Artery By | 2002 |
Propacetamol as adjunctive treatment for postoperative pain after cardiac surgery.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Coronary Artery By | 2002 |
Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; An | 2002 |
Analgesia for paediatric tonsillectomy and adenoidectomy with intramuscular clonidine.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Adrenergic alpha-Agonists; Ambulatory Surgical | 2002 |
Caudal neostigmine, bupivacaine, and their combination for postoperative pain management after hypospadias surgery in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; Child, Preschool; D | 2002 |
Attenuation of pain in a randomized trial by suppression of peripheral nociceptive activity in the immediate postoperative period.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesthesia, | 2002 |
Trials and tribulations: current challenges in conducting clinical trials.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Cholecystectomy, Laparoscopic; Clinical Trials, | 2003 |
[Postoperative comfort in pediatric outpatient tonsillectomy].
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2002 |
EMLA cream versus dorsal penile nerve block for postcircumcision analgesia in children.
Topics: Acetaminophen; Administration, Topical; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, C | 2003 |
Postoperative pain relief after hepatic resection in cirrhotic patients: the efficacy of a single small dose of ketamine plus morphine epidurally.
Topics: Acetaminophen; Adult; Aged; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Anesthetics, Dissoc | 2003 |
Prospective study on incidence and functional impact of transient neurologic symptoms associated with 1% versus 5% hyperbaric lidocaine in short urologic procedures.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, | 2003 |
A study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthe | 2002 |
Adjunctive analgesia with intravenous propacetamol does not reduce morphine-related adverse effects.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics; Analgesics, Opioid | 2003 |
An investigation into the comparative efficacy of soluble aspirin and solid paracetamol in postoperative pain after third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non- | 2003 |
Analgesic effect of i.v. paracetamol: possible ceiling effect of paracetamol in postoperative pain.
Topics: Absorption; Acetaminophen; Adult; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthes | 2003 |
Randomized, double-blind, placebo-controlled comparison of the analgesic efficacy of oxycodone 10 mg/acetaminophen 325 mg versus controlled-release oxycodone 20 mg in postsurgical pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Delayed-Action Preparations; Dose-Response Relationshi | 2003 |
Ketoprofen 75 mg qid versus acetaminophen 1000 mg qid for 3 days on swelling, pain, and other postoperative events after third-molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
A randomized, double-blind crossover trial of paracetamol 1000 mg four times daily vs ibuprofen 600 mg: effect on swelling and other postoperative events after third molar surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over Studies | 2003 |
Systematic evaluation of pain in neonates: effect on the number of intravenous analgesics prescribed.
Topics: Acetaminophen; Analgesics; Cohort Studies; Drug Utilization; Fentanyl; Humans; Infant, Newborn; Infa | 2003 |
Randomized, double-blind, placebo-controlled study of the effect of rectal paracetamol on morphine consumption after abdominal hysterectomy.
Topics: Acetaminophen; Administration, Rectal; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Postoperative analgesia in children undergoing myringotomy and placement equalization tubes in ambulatory surgery.
Topics: Acetaminophen; Administration, Intranasal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; | 2003 |
Paracetamol and metabolite pharmacokinetics in infants.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Infant; Male; Metabolic Clearance Rate; Pai | 2003 |
Meta-analysis of single dose oral tramadol plus acetaminophen in acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Do | 2003 |
Does ketamine or magnesium affect posttonsillectomy pain in children?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Child; Child | 2003 |
An evaluation of the safety and efficacy of administering rofecoxib for postoperative pain management.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2003 |
Dose response study of caudal neostigmine for postoperative analgesia in paediatric patients undergoing genitourinary surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Caudal; Child; Child, Preschool; Cholinesterase | 2003 |
[A randomized, double blind, and controlled clinical trial of the non-addictive propacetamol in postoperative analgesia].
Topics: Acetaminophen; Adult; Aged; Analgesics; Double-Blind Method; Female; Humans; Male; Meperidine; Middl | 2003 |
Analgesic efficacy of rectal acetaminophen and ibuprofen alone or in combination for paediatric day-case adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Ambulatory Surgical Procedures; Analgesics, No | 2003 |
Analgesic efficacy and tolerability of ketoprofen lysine salt vs paracetamol in common paediatric surgery. A randomized, single-blind, parallel, multicentre trial.
Topics: Acetaminophen; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Anesthesia, Epidural; A | 2003 |
Naproxen 500 mg bid versus acetaminophen 1000 mg qid: effect on swelling and other acute postoperative events after bilateral third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Confidence | 2003 |
Analgesic efficacy of low-dose diclofenac versus paracetamol and placebo in postoperative dental pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analysis of Variance; Anti-Inflammatory Agents, Non- | 2003 |
[Impact of 2 strategies of analgesia on postoperative pain after emergency hand surgery performed on an ambulatory basis].
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; An | 2003 |
Evaluation of postoperative bupivacaine infusion for pain management after anterior cruciate ligament reconstruction.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anterior Cruciate Li | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Comparison of the effects of 2 doses of methylprednisolone on pain, swelling, and trismus after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cross-Over Stu | 2003 |
Sub-Tenon's block reduces both intraoperative and postoperative analgesia requirement in vitreo-retinal surgery under general anaesthesia.
Topics: Acetaminophen; Aged; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; | 2003 |
Assessing analgesia in single and repeated administrations of propacetamol for postoperative pain: comparison with morphine after dental surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2004 |
Efficacy of scheduled nonnarcotic analgesic medications in children after suboccipital craniectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Arnold-Chiari Malformation; Child; Child, Preschool; C | 2004 |
Controlled-release codeine is equivalent to acetaminophen plus codeine for post-cholecystectomy analgesia.
Topics: Acetaminophen; Adult; Aged; Cholecystectomy, Laparoscopic; Codeine; Double-Blind Method; Drug Therap | 2004 |
Combination tramadol plus acetaminophen for postsurgical pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Double-Blind M | 2004 |
Pediatric tonsillotomy with the radiofrequency technique: less morbidity and pain.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2004 |
A double-blind placebo-controlled comparison of tramadol/acetaminophen and tramadol in patients with postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Dizziness; Double-Bl | 2004 |
Dose-dependent efficacy of diclofenac-cholestyramine on pain and periarticular ossifications after total hip arthroplasty: a double-blind, prospective, randomised trial.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N | 2004 |
Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: a randomized, double-blind, placebo-controlled study in patients with moderate to severe postoperative pain in the third molar extraction model.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Doubl | 2004 |
A double-blind randomised controlled clinical trial of the effect of preoperative ibuprofen, diclofenac, paracetamol with codeine and placebo tablets for relief of postoperative pain after removal of impacted third molars.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Ascorbic Acid; Codeine; Diclofenac; Double-Blind | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The efficacy of pain control following nonsurgical root canal treatment using ibuprofen or a combination of ibuprofen and acetaminophen in a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Double-Blind Method; Drug C | 2004 |
The effect of fusafungine on post-operative pain and wound healing after pediatric tonsillectomy.
Topics: Acetaminophen; Adolescent; Aerosols; Amoxicillin-Potassium Clavulanate Combination; Analgesics, Non- | 2004 |
Ibuprofen vs. acetaminophen vs. ibuprofen and acetaminophen after arthroscopically assisted anterior cruciate ligament reconstruction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, General; Anterior Cruciate Ligament; Ant | 2004 |
A randomized clinical trial of the effectiveness of a scheduled oral analgesic dosing regimen for the management of postoperative pain in children following tonsillectomy.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics; Analysis of Variance; Child; Codeine; D | 2004 |
A randomized clinical trial of the effectiveness of a scheduled oral analgesic dosing regimen for the management of postoperative pain in children following tonsillectomy.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics; Analysis of Variance; Child; Codeine; D | 2004 |
A randomized clinical trial of the effectiveness of a scheduled oral analgesic dosing regimen for the management of postoperative pain in children following tonsillectomy.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics; Analysis of Variance; Child; Codeine; D | 2004 |
A randomized clinical trial of the effectiveness of a scheduled oral analgesic dosing regimen for the management of postoperative pain in children following tonsillectomy.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics; Analysis of Variance; Child; Codeine; D | 2004 |
Evaluation of adding preoperative or postoperative rectal paracetamol to caudal bupivacaine for postoperative analgesia in children.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anesthetics, Lo | 2004 |
Preoperative intravenous tramadol versus ketorolac for preventing postoperative pain after third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflamm | 2004 |
The analgesic efficacy of etoricoxib compared with oxycodone/acetaminophen in an acute postoperative pain model: a randomized, double-blind clinical trial.
Topics: Acetaminophen; Acute Disease; Adult; Double-Blind Method; Drug Therapy, Combination; Etoricoxib; Fem | 2004 |
Onset of analgesia and analgesic efficacy of tramadol/acetaminophen and codeine/acetaminophen/ibuprofen in acute postoperative pain: a single-center, single-dose, randomized, active-controlled, parallel-group study in a dental surgery pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Opioid; Codeine; Drug Combinations; Female; | 2004 |
Propacetamol and diclofenac alone and in combination for analgesia after elective tonsillectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ant | 2004 |
Propacetamol and diclofenac alone and in combination for analgesia after elective tonsillectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ant | 2004 |
Propacetamol and diclofenac alone and in combination for analgesia after elective tonsillectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ant | 2004 |
Propacetamol and diclofenac alone and in combination for analgesia after elective tonsillectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Ant | 2004 |
Relative efficacy of oral analgesics after third molar extraction.
Topics: Acetaminophen; Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Codeine; C | 2004 |
The postoperative analgesic effect of tramadol when used as subcutaneous local anesthetic.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; | 2004 |
[Postoperative pain therapy after tonsillectomy in children. An observational study for 7 days].
Topics: Acetaminophen; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Ant | 2005 |
Preoperative ketorolac has a preemptive effect for postoperative third molar surgical pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over | 2004 |
The preoperative administration of ketoprofen improves analgesia after laparoscopic cholecystectomy in comparison with propacetamol or postoperative ketoprofen.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal | 2005 |
Opioid-sparing effects of diclofenac and paracetamol lead to improved outcomes after cardiac surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2004 |
[Comparison of preemptive analgesia efficacy between etoricoxib and rofecoxib in ambulatory gynecological surgery].
Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics, Non | 2004 |
Onset of acetaminophen analgesia: comparison of oral and intravenous routes after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; H | 2005 |
Onset of acetaminophen analgesia: comparison of oral and intravenous routes after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; H | 2005 |
Onset of acetaminophen analgesia: comparison of oral and intravenous routes after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; H | 2005 |
Onset of acetaminophen analgesia: comparison of oral and intravenous routes after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; H | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
Efficacy and safety of single and repeated administration of 1 gram intravenous acetaminophen injection (paracetamol) for pain management after major orthopedic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Ar | 2005 |
A randomized, double-blind comparison between parecoxib sodium and propacetamol for parenteral postoperative analgesia after inguinal hernia repair in adult patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhi | 2005 |
Propacetamol and ketoprofen after thyroidectomy.
Topics: Acetaminophen; Analgesics, Opioid; Analysis of Variance; Anesthesia, General; Anti-Inflammatory Agen | 2005 |
Analgesic efficacy and tolerability of oxycodone 5 mg/ibuprofen 400 mg compared with those of oxycodone 5 mg/acetaminophen 325 mg and hydrocodone 7.5 mg/acetaminophen 500 mg in patients with moderate to severe postoperative pain: a randomized, double-blin
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2005 |
Time-contingent dosing of an opioid analgesic after tonsillectomy does not increase moderate-to-severe side effects in children.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Codeine; Drug Administration Schedule; Drug Co | 2005 |
Time-contingent dosing of an opioid analgesic after tonsillectomy does not increase moderate-to-severe side effects in children.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Codeine; Drug Administration Schedule; Drug Co | 2005 |
Time-contingent dosing of an opioid analgesic after tonsillectomy does not increase moderate-to-severe side effects in children.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Codeine; Drug Administration Schedule; Drug Co | 2005 |
Time-contingent dosing of an opioid analgesic after tonsillectomy does not increase moderate-to-severe side effects in children.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Codeine; Drug Administration Schedule; Drug Co | 2005 |
Intravenous acetaminophen (paracetamol): comparable analgesic efficacy, but better local safety than its prodrug, propacetamol, for postoperative pain after third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Inf | 2005 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Interventions for relieving pain associated with panretinal photocoagulation: a prospective randomized trial.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Local; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2006 |
Tolerance and analgesic efficacy of a new i.v. paracetamol solution in children after inguinal hernia repair.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, General; Child; Child, Preschool; Double-Blind | 2005 |
Acetaminophen decreases early post-thoracotomy ipsilateral shoulder pain in patients with thoracic epidural analgesia: a double-blind placebo-controlled study.
Topics: Acetaminophen; Administration, Rectal; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia, Epidur | 2005 |
Analgesic efficacy and safety of intravenous paracetamol (acetaminophen) administered as a 2 g starting dose following third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthetics, Intravenous; Dose-Response Relationship | 2006 |
The analgesic efficacy of intravenous versus oral tramadol for preventing postoperative pain after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia | 2005 |
Postoperative epidural morphine for postpartum tubal ligation analgesia.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesic | 2005 |
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar | 2005 |
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar | 2005 |
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar | 2005 |
Intravenous acetaminophen reduced the use of opioids compared with oral administration after coronary artery bypass grafting.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coronary Ar | 2005 |
Analgesic efficacy of diclofenac in combination with morphine and paracetamol after mastectomy and immediate breast reconstruction.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, | 2005 |
Continuous intra-articular infusion of bupivacaine for postoperative pain following total knee arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; An | 2005 |
Continuous intra-articular infusion of bupivacaine for postoperative pain following total knee arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; An | 2005 |
Continuous intra-articular infusion of bupivacaine for postoperative pain following total knee arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; An | 2005 |
Continuous intra-articular infusion of bupivacaine for postoperative pain following total knee arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Analgesics, Opioid; An | 2005 |
Analgesic efficacy of rofecoxib compared with codeine/acetaminophen using a model of acute dental pain.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analy | 2005 |
Bupivacaine/ketamine is superior to intra-articular ketamine analgesia following arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Dissociative; Anest | 2005 |
Intermittent injection of bupivacaine into the margin or the cavity after reduction mammaplasty.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Dextro | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
The effect of music therapy on postoperative pain, heart rate, systolic blood pressures and analgesic use following nasal surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia; Analgesics; Blood Pressure; Diclofenac; Female; H | 2005 |
A comparison between IV paracetamol and IV metamizol for postoperative analgesia after retinal surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Dipyrone; Double-Blind Method; | 2005 |
Outpatient varicocelectomy performed under local anesthesia.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anesthesia, Local; Anesthetics, Lo | 2005 |
Pre-incision infiltration of local anesthetic reduces postoperative pain with no effects on bruising and wound cosmesis after thyroid surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Local; Anesthetics, | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Effect of oral gabapentin on postoperative epidural analgesia.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Amines; Analgesia, Epidural; Analgesia, Patient-Co | 2006 |
Analgesic efficacy of tramadol by route of administration in a clinical model of pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2005 |
Double masked randomised controlled trial to assess the effectiveness of paracetamol in reducing pain in panretinal photocoagulation.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Diabetic Retinopathy; Double-Blind Method; Fem | 2006 |
Gabapentin attenuates late but not acute pain after abdominal hysterectomy.
Topics: Acetaminophen; Adult; Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Codeine | 2006 |
Tramadol/acetaminophen tablets in the treatment of postsurgical orthopedic pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Codeine; D | 2005 |
Analgesic efficacy of parenteral paracetamol (propacetamol) and diclofenac in post-operative orthopaedic pain.
Topics: Acetaminophen; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Diclof | 2006 |
[Administration of Perfalgan (paracetamol) for postoperative analgesia in obstetrics and gynaecology].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Therapy, Combination; Female; Gyne | 2005 |
Oral analgesia compared with intravenous patient-controlled analgesia for pain after cesarean delivery: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Patient-Controlled; Analgesics; Cesarean Sect | 2006 |
Rofecoxib versus hydrocodone/acetaminophen for postoperative analgesia in functional endoscopic sinus surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Non-Narcotic; Anal | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
Effects of intraoperative i.v. acetaminophen vs i.m. meperidine on post-tonsillectomy pain in children.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2006 |
The analgesic efficacy of acetaminophen, ketoprofen, or their combination for pediatric surgical patients having soft tissue or orthopedic procedures.
Topics: Acetaminophen; Analgesics; Analysis of Variance; Chi-Square Distribution; Child; Child, Preschool; D | 2006 |
Zolpidem reduces postoperative pain, fatigue, and narcotic consumption following knee arthroscopy: a prospective randomized placebo-controlled double-blinded study.
Topics: Acetaminophen; Arthroscopy; Double-Blind Method; Drug Combinations; Fatigue; Female; Humans; Hydroco | 2006 |
Analgesic effect of electroacupuncture in postthoracotomy pain: a prospective randomized trial.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; | 2006 |
[Postoperative pain management in clinics of otolaryngology].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Dipyrone; Etodolac; Female; Humans; Lactones; Ma | 2006 |
[Analgesia in colon surgery. Can the use of NSAIDs reduce the opioid consumption following conventional and laparoscopic interventions?].
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; | 2006 |
The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
The efficacy of the non-opioid analgesics parecoxib, paracetamol and metamizol for postoperative pain relief after lumbar microdiscectomy.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2006 |
Efficacy of three doses of tramadol with bupivacaine for caudal analgesia in paediatric inguinal herniotomy.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recover | 2006 |
Oral oxycodone hydrochloride versus epidural anaesthesia for pain control after radical retropubic prostatectomy.
Topics: Acetaminophen; Administration, Oral; Aged; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Na | 2006 |
Intravenous magnesium sulphate decreases postoperative tramadol requirement after radical prostatectomy.
Topics: Acetaminophen; Aged; Analgesia; Analgesia, Patient-Controlled; Double-Blind Method; Drug Synergism; | 2006 |
Dental impaction pain model as a potential tool to evaluate drugs with efficacy in neuropathic pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; | 2006 |
Comparison of oral versus rectal administration of acetaminophen with codeine in postoperative pediatric adenotonsillectomy patients.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Administration, Rectal; Child, Preschool; Codein | 2006 |
Effect of intraoperative intravenous acetaminophen vs. intramuscular meperidine on pain and discharge time after paediatric dental restoration.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Child; Child, Pres | 2007 |
Efficacy of a fixed dose combination of diclofenac sodium and acetaminophen (Rhumacort) injection in postoperative pain.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Drug Combinations; Female | 2006 |
Combining paracetamol with a selective cyclooxygenase-2 inhibitor for acute pain relief after third molar surgery: a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cohort Studies; Cyclooxygenase 2 Inhibitors; Double- | 2006 |
Can postoperative pains following tonsillectomy be relieved by honey? A prospective, randomized, placebo controlled preliminary study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Drug Therapy, Combination; Female; Honey; Humans; Ma | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Preincisional paravertebral block reduces the prevalence of chronic pain after breast surgery.
Topics: Acetaminophen; Analgesia, Epidural; Breast Neoplasms; Bupivacaine; Codeine; Follow-Up Studies; Human | 2006 |
Efficacy of suppository analgesia in postabortion pain reduction.
Topics: Acetaminophen; Adolescent; Adult; Aftercare; Analgesia; Analgesics; Drug Administration Routes; Fema | 2006 |
Plasma concentrations following repeated rectal or intravenous administration of paracetamol after heart surgery.
Topics: Acetaminophen; Administration, Rectal; Aged; Analgesics, Non-Narcotic; Cardiac Surgical Procedures; | 2006 |
Etoricoxib pre-medication for post-operative pain after laparoscopic cholecystectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Ana | 2006 |
The associations between severity of early postoperative pain, chronic postsurgical pain and plasma concentration of stable nitric oxide products after breast surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia; Anxiety; Breast Neoplasms; Bupivacaine; Celecoxib; Chronic Di | 2006 |
Clinical equivalence of IV paracetamol compared to IV dipyrone for postoperative analgesia after surgery for breast cancer.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Breast Neoplasms; Dipyrone; Double-Blind Method; Fem | 2006 |
Postoperative pain management after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Craniotomy; Cyclooxygenase 2 Inhibitors; Dose- | 2006 |
Topical lidocaine and oral acetaminophen provide similar analgesia for myringotomy and tube placement in children.
Topics: Acetaminophen; Administration, Oral; Administration, Topical; Analgesics, Non-Narcotic; Anesthetics, | 2006 |
Comparison of bupivacaine and ropivacaine on postoperative pain after tonsillectomy in paediatric patients.
Topics: Acetaminophen; Adolescent; Amides; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Child; | 2007 |
Intraarticular tramadol plus pericapsular incisional bupivacaine provides better analgesia than intraarticular plus pericapsular incisional bupivacaine after outpatient arthroscopic partial meniscectomy.
Topics: Acetaminophen; Adult; Ambulatory Care; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Lo | 2007 |
Intravenous acetaminophen vs oral ibuprofen in combination with morphine PCIA after Cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesia, Patient-Controlled; A | 2006 |
Acetaminophen is highly effective in pain treatment after endoscopic sinus surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chronic Disease; Double-Blind Method; Endoscopy; Fem | 2006 |
Acetaminophen selectively suppresses peripheral prostaglandin E2 release and increases COX-2 gene expression in a clinical model of acute inflammation.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Cyclooxygenase 2; Dinoprostone; Female; | 2007 |
The efficacy of rofecoxib 50 mg and hydrocodone/acetaminophen 7.5/750 mg in patients with post-arthroscopic pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Arthroscop | 2007 |
[Evaluation of postoperative analgesia with continuous iliofascial nerve sheath block after total hip arthroplasty replacement: a pilot study].
Topics: Acetaminophen; Aged; Aged, 80 and over; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narco | 2007 |
The post-operative analgesic effects of a combination of gabapentin and paracetamol in patients undergoing abdominal hysterectomy: a randomized clinical trial.
Topics: Acetaminophen; Adult; Algorithms; Amines; Analgesics; Analgesics, Opioid; Anesthetics, Combined; Cyc | 2007 |
Management of postoperative pain in children following extractions of primary teeth under general anaesthesia: a comparison of paracetamol, Voltarol and no analgesia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia, General; Chi-Square Distrib | 2007 |
Rectal acetaminophen does not reduce morphine consumption after major surgery in young infants.
Topics: Abdomen; Acetaminophen; Administration, Rectal; Algorithms; Analgesics, Non-Narcotic; Analgesics, Op | 2007 |
Cost analysis applied to postoperative analgesia regimens: a comparison between parecoxib and propacetamol.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cost-Benefit Analysis; Cyclooxygenase | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
A comparison of paracetamol, ibuprofen or their combination for pain relief following extractions in children under general anaesthesia: a randomized controlled trial.
Topics: Acetaminophen; Administration, Oral; Age Factors; Analgesics, Non-Narcotic; Anesthesia Recovery Peri | 2007 |
Early oral analgesia after fast-track cardiac anesthesia.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesia; Analgesics, Opioid; Anesthesia; Anti-Inflammat | 2007 |
Oral naproxen but not oral paracetamol reduces the need for rescue analgesic after adenoidectomy in children.
Topics: Acetaminophen; Adenoidectomy; Administration, Inhalation; Administration, Oral; Analgesics; Anti-Inf | 2007 |
When to add supplemental rectal paracetamol for postoperative analgesia with caudal bupivacaine in children? A prospective, double-blind, randomized study.
Topics: Acetaminophen; Administration, Rectal; Analgesia; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anes | 2007 |
Pain treatment and recovery after endoscopic sinus surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Endoscopy; Female; Follow-Up Studi | 2007 |
Intravenous paracetamol as adjunctive treatment for postoperative pain after cardiac surgery: a double blind randomized controlled trial.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cardiac Surgical Procedures; Chem | 2007 |
A double-blind randomized controlled trial of rofecoxib and multidose oxycodone/acetaminophen in dental impaction pain.
Topics: Acetaminophen; Adult; Analgesics; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Dou | 2007 |
Assessment of early postoperative pain and haemorrhage in young children undergoing dental extractions under general anaesthesia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Dental; Anesthesia, | 2007 |
Effect of 3 g of intravenous paracetamol on post-operative analgesia, platelet function and liver enzymes in patients undergoing tonsillectomy under local anaesthesia.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Local; Anti-Inflammatory Agents, Non-Ste | 2007 |
Obturator versus femoral nerve block for analgesia after total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, | 2007 |
Wound infiltration with levobupivacaine: an alternative method of postoperative pain relief after inguinal hernia repair in children.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anesthetics, Local; Bupivacaine; Ch | 2007 |
Intravenous paracetamol is highly effective in pain treatment after tonsillectomy in adults.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Double-Blind Method; Female; Humans; Male; Pain Meas | 2008 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Effects of reduction of the caudal morphine dose in paediatric circumcision on quality of postoperative analgesia and morphine-related side-effects.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Circumcisio | 2007 |
Effects of reduction of the caudal morphine dose in paediatric circumcision on quality of postoperative analgesia and morphine-related side-effects.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Circumcisio | 2007 |
Effects of reduction of the caudal morphine dose in paediatric circumcision on quality of postoperative analgesia and morphine-related side-effects.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Circumcisio | 2007 |
Effects of reduction of the caudal morphine dose in paediatric circumcision on quality of postoperative analgesia and morphine-related side-effects.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Circumcisio | 2007 |
Peritonsillar infiltration with tramadol improves pediatric tonsillectomy pain.
Topics: Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Double-Blind Method; Female; Humans; Mal | 2008 |
Effect of submucosal injection of dexamethasone on postoperative discomfort after third molar surgery: a prospective study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anesthesia, Local; Anti-Inflammatory Agents; Dexamet | 2007 |
Comparative study of acetaminophen-morphine versus rofecoxib-morphine for post-tonsillectomy pain control.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; | 2007 |
A double-blind randomised controlled trial of paracetamol, diclofenac or the combination for pain relief after caesarean section.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient-Controlled; An | 2008 |
Pre-operative analgesia with rectal diclofenac and/or paracetamol in children undergoing inguinal hernia repair.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammato | 2007 |
Administration of fentanyl before remifentanil-based anaesthesia has no influence on post-operative pain or analgesic consumption.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Anesthesia, Intra | 2008 |
Operative treatment of midclavicular fractures in 62 elderly patients: knowles pin versus plate.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Bone Nails; Bo | 2007 |
Comparative safety and efficacy of two high dose regimens of oral paracetamol in healthy adults undergoing third molar surgery under local anaesthesia.
Topics: Acetaminophen; Administration, Oral; Adult; Anesthesia, Dental; Anesthesia, Local; Anti-Inflammatory | 2007 |
Clinical analgesic efficacy and side effects of dexmedetomidine in the early postoperative period after arthroscopic knee surgery.
Topics: Acetaminophen; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Age | 2007 |
Peritonsillar infiltration with bupivacaine and pethidine for relief of post-tonsillectomy pain: a randomised double-blind study.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivac | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The analgesic efficacy of transversus abdominis plane block after cesarean delivery: a randomized controlled trial.
Topics: Abdominal Wall; Acetaminophen; Adult; Amides; Analgesia, Patient-Controlled; Analgesics, Non-Narcoti | 2008 |
The differential effects of bupivacaine and lidocaine on prostaglandin E2 release, cyclooxygenase gene expression and pain in a clinical pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; | 2008 |
Randomized controlled trial of duration of analgesia following intravenous or rectal acetaminophen after adenotonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2008 |
Oral gabapentin for the treatment of postoperative pain after photorefractive keratectomy.
Topics: Acetaminophen; Administration, Oral; Adult; Amines; Analgesics; Anti-Bacterial Agents; Cyclohexaneca | 2008 |
Effect of the proteolytic enzyme serrapeptase on swelling, pain and trismus after surgical extraction of mandibular third molars.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cross-Over | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
A randomized controlled trial comparing acetaminophen plus ibuprofen versus acetaminophen plus codeine plus caffeine after outpatient general surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Caffeine; Centra | 2008 |
Comparison of caudal epidural bupivacaine with bupivacaine plus tramadol and bupivacaine plus ketamine for postoperative analgesia in children.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Disso | 2008 |
Effect of paracetamol and coxib with or without dexamethasone after laparoscopic cholecystectomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Cholecystectom | 2008 |
Analgesic efficacy of intravenous paracetamol for outpatient fractional curettage: a randomised, controlled trial.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Dilatation and Curettage; Double-Blind Me | 2009 |
Pharmacokinetics and analgesic effects of intravenous propacetamol vs rectal paracetamol in children after major craniofacial surgery.
Topics: Acetaminophen; Administration, Rectal; Analgesia; Analgesics; Anesthetics, Intravenous; Child, Presc | 2008 |
The visual analog scale in multiple-dose evaluations of analgesics.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Codeine; Dextropropo | 1981 |
Analgesia following adult tonsillectomy: a comparative study of solpadeine and a soluble form of dextropropoxyphene napsylate and paracetamol.
Topics: Acetaminophen; Adult; Aged; Analgesics; Caffeine; Codeine; Dextropropoxyphene; Drug Combinations; Dr | 1982 |
Ibuprofen in the treatment of postoperative pain.
Topics: Acetaminophen; Age Factors; Analgesics, Opioid; Anesthesia, Epidural; Aspirin; Cholecystectomy; Clin | 1984 |
[Postoperative pain: comparative study of the analgesic effect of sodium naproxen and paracetamol].
Topics: Acetaminophen; Adult; Double-Blind Method; Female; Humans; Male; Naproxen; Pain, Postoperative; Rand | 1984 |
Suppression of postoperative pain by preoperative administration of ibuprofen in comparison to placebo, acetaminophen, and acetaminophen plus codeine.
Topics: Acetaminophen; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Therapy, Combination; Hu | 1983 |
Analgesic efficacy and plasma concentration of three analgesics in pain after lower third molar removal.
Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Codeine; Female; Humans; Male; Molar, Third | 1983 |
[Clinical evaluation of a new analgesic UP 341.01 in patients with pain following orthopedic surgery].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Bone Diseases; Clinical Trials as Topic; Female; | 1983 |
[Treatment of postoperative wound pain with suprofen].
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Fema | 1983 |
Double-blind evaluation of suprofen and aspirin in the treatment of periodontal pain.
Topics: Acetaminophen; Adult; Aspirin; Clinical Trials as Topic; Codeine; Double-Blind Method; Female; Human | 1983 |
Caffeine as an analgesic adjuvant.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Analgesics; Aspirin; Caffeine; Clinical Trials as Topic; Dou | 1984 |
Comparison of ibuprofen and acetaminophen-codeine in postoperative foot pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug | 1984 |
The efficacy of diclofenac sodium (Voltarol) with and without paracetamol in the control of post-surgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Diclofenac; Double-Blind Method; Drug Co | 1984 |
A controlled comparative evaluation of acetaminophen and aspirin in the treatment of postoperative pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Double-Blind Method; Fema | 1984 |
Comparison of a traditional paracetamol medication and a new paracetamol/paracetamol-methionine ester combination.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics; Drug Combinations; Female; Humans; Male; Pa | 1984 |
Analgesic efficacy after single and repeated doses of codeine and acetaminophen.
Topics: Acetaminophen; Adult; Analgesia; Codeine; Humans; Pain, Postoperative; Tooth Extraction | 1984 |
Paracetamol plus supplementary doses of codeine. An analgesic study of repeated doses.
Topics: Acetaminophen; Clinical Trials as Topic; Codeine; Dose-Response Relationship, Drug; Double-Blind Met | 1982 |
Postoperative analgesics for superficial surgery. Comparison of four analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aminopyrine; Aspirin; Benzilates; Benzophenones; Clinical Tr | 1981 |
An analgesic study with repeated doses of phenazone, phenazone plus dextropropoxyphene, and paracetamol, using a visual analogue scale.
Topics: Acetaminophen; Adolescent; Adult; Antipyrine; Clinical Trials as Topic; Dextropropoxyphene; Double-B | 1982 |
Effect of caffeine on acetaminophen analgesia.
Topics: Acetaminophen; Analgesia; Analysis of Variance; Caffeine; Dose-Response Relationship, Drug; Drug Com | 1983 |
Effect of preoperative paracetamol on pain after oral surgery.
Topics: Acetaminophen; Adult; Double-Blind Method; Female; Humans; Male; Molar, Third; Pain, Postoperative; | 1983 |
An evaluation of the analgesic efficacy of three opioid-analgesic combinations in postoperative oral surgery pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Codeine; Drug Combinations; Female; Humans; H | 1981 |
Analgesia following dental surgery: a comparison of brufen and distalgesic.
Topics: Acetaminophen; Adolescent; Adult; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Female | 1981 |
Comparison of the analgesic efficacy of fluproquazone, propoxyphene and paracetamol in post-hysterectomy pain. Short communication.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Dextropropoxyphene; Female; Humans; Hysterec | 1981 |
A controlled comparison of dipyrone and paracetamol in post-episiotomy pain.
Topics: Acetaminophen; Adult; Aminopyrine; Clinical Trials as Topic; Dipyrone; Double-Blind Method; Episioto | 1980 |
Analgesic and anti-inflammatory effects of paracetamol evaluated by bilateral oral surgery.
Topics: Acetaminophen; Adult; Analgesics; Anti-Inflammatory Agents; Body Temperature; Clinical Trials as Top | 1980 |
Evaluation of oxycodone and acetaminophen in treatment of postoperative dental pain.
Topics: Acetaminophen; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Combinations; Female; Hu | 1980 |
Double-blind evaluation of naproxen and ibuprofen in periodontal surgery.
Topics: Acetaminophen; Aspirin; Clinical Trials as Topic; Double-Blind Method; Female; Gingivectomy; Humans; | 1980 |
Clinical evaluation of fluproquazone in post-operative pain. A report of double-blind comparative trials in patients after surgical interventions.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Double-Blin | 1981 |
Pharmacokinetics of parenteral paracetamol and its analgesic effects in post-operative dental pain.
Topics: Acetaminophen; Analgesics; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Injections | 1981 |
Postsurgical pain: zomepirac sodium, propoxyphene/-acetaminophen combination, and placebo.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Dextropropoxyphene; Do | 1981 |
An oral buprenorphine and paracetamol combination compared with paracetamol alone: a single dose double-blind postoperative study.
Topics: Acetaminophen; Adult; Buprenorphine; Clinical Trials as Topic; Double-Blind Method; Drug Combination | 1981 |
Zomepirac, placebo and paracetamol/dextropropoxyphene combination compared in orthopaedic postoperative pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Bone and Bones; Clinical Trials as Topic; Dextropropox | 1982 |
Codeine added to paracetamol induced adverse effects but did not increase analgesia.
Topics: Acetaminophen; Adolescent; Adult; Body Temperature; Codeine; Double-Blind Method; Drug Combinations; | 1982 |
Clinical efficacy of mild analgesics in pain following gynaecological or dental surgery: report on multicentre studies.
Topics: Acetaminophen; Adult; Analgesics; Dipyrone; Episiotomy; Female; Humans; Male; Pain, Postoperative; T | 1980 |
Lack of analgesic effect of 50 and 100 mg oral tramadol after orthopaedic surgery: a randomized, double-blind, placebo and standard active drug comparison.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bone and Bones; Bup | 1995 |
The effect of ketorolac as an adjuvant to local anaesthetic infiltration for analgesia in paediatric umbilical hernia surgery.
Topics: Acetaminophen; Adjuvants, Anesthesia; Analgesia; Analgesics, Non-Narcotic; Anesthetics, Local; Anti- | 1995 |
Postoperative morphine requirements, nausea and vomiting following anaesthesia for tonsillectomy. Comparison of intravenous morphine and non-opioid analgesic techniques.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia Recove | 1995 |
Pharmacokinetics of rectal paracetamol after major surgery in children.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Biological Availability; Child; Fem | 1995 |
An assessment of the efficacy and tolerability of nimesulide vs paracetamol in children after adenotonsillectomy.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Preschool; Female; Humans; Inf | 1993 |
The morphine-sparing effect of propacetamol in orthopedic postoperative pain.
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Female; Humans; Male; Morphine; Orthopedics; | 1995 |
A comparison of crossover versus parallel-group design in the evaluation of analgesic efficacy after molar extraction.
Topics: Acetaminophen; Analgesics; Codeine; Cross-Over Studies; Double-Blind Method; Doxylamine; Drug Combin | 1995 |
Intravenous regional anesthesia using lidocaine and ketorolac.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Conduction; Anesthesia, Intravenous; Anti-Infla | 1995 |
[Strabismus surgery in children. The effect of paracetamol and bupivacaine].
Topics: Acetaminophen; Anesthesia; Arousal; Bupivacaine; Child, Preschool; Female; Humans; Male; Pain Measur | 1995 |
Evaluation of piroxicam-beta-cyclodextrin, piroxicam, paracetamol and placebo in post-operative oral surgery pain.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclo | 1994 |
Normal postoperative gastric emptying after orthopaedic surgery with spinal anaesthesia and i.m. ketorolac as the first postoperative analgesic.
Topics: Acetaminophen; Aged; Anesthesia, Spinal; Female; Gastric Emptying; Humans; Injections, Intramuscular | 1995 |
Regional anaesthesia for hernia repair in children: local vs caudal anaesthesia.
Topics: Acetaminophen; Adolescent; Anesthesia Recovery Period; Anesthesia, Caudal; Anesthesia, Local; Bupiva | 1995 |
The effects of ketorolac and fentanyl on postoperative vomiting and analgesic requirements in children undergoing strabismus surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia; Child; Child, P | 1995 |
The effect of post-operative diet on recovery in the first twelve hours after tonsillectomy and adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Beverages; Child; Child Behavior; Child, Preschool; Diet; | 1995 |
[Comparison of the analgesic efficacy of nalbuphine and its combination with propacetamol during the immediate postoperative period in gynecologic-obstetric surgery].
Topics: Acetaminophen; Adult; Analgesics; Cesarean Section; Drug Combinations; Female; Genital Diseases, Fem | 1994 |
Analgesia for outpatient surgery: placebo versus naproxen sodium (a non-steroidal anti-inflammatory drug) given before or after surgery.
Topics: Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesia; Bone and Bones; Double- | 1994 |
Effectiveness of various medications on postoperative pain following complete instrumentation.
Topics: Acetaminophen; Adult; Analysis of Variance; Chi-Square Distribution; Codeine; Dental Anxiety; Erythr | 1994 |
Effectiveness of various medications on postoperative pain following root canal obturation.
Topics: Acetaminophen; Adult; Aged; Analysis of Variance; Chi-Square Distribution; Codeine; Erythromycin; Fe | 1994 |
Pre-emptive analgesia: comparison of preoperative with postoperative caudal block on postoperative pain in children.
Topics: Acetaminophen; Analgesia, Epidural; Anesthesia, General; Child; Child, Preschool; Circumcision, Male | 1994 |
Analgesic efficacy of flurbiprofen in comparison with acetaminophen, acetaminophen plus codeine, and placebo after impacted third molar removal.
Topics: Acetaminophen; Administration, Oral; Adult; Codeine; Double-Blind Method; Drug Combinations; Female; | 1994 |
The effect of balanced analgesia on early convalescence after major orthopaedic surgery.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia; Analgesia, Epidural; Anesthesia, Epidural; Anesth | 1994 |
Laparoscopic versus open appendicectomy: prospective randomised trial.
Topics: Acetaminophen; Adult; Appendectomy; Appendicitis; Female; Follow-Up Studies; Humans; Intraoperative | 1993 |
Analgesic efficiency of propacetamol hydrochlorid after lumbar disc surgery.
Topics: Acetaminophen; Adult; Analgesics; Drug Therapy, Combination; Female; Humans; Intervertebral Disc Dis | 1993 |
Comparison of a bupivacaine-clonidine mixture with plain bupivacaine for caudal analgesia in children.
Topics: Acetaminophen; Analgesia, Epidural; Bupivacaine; Cauda Equina; Child; Child, Preschool; Clonidine; D | 1994 |
Acetaminophen analgesia in neonatal circumcision: the effect on pain.
Topics: Acetaminophen; Circumcision, Male; Double-Blind Method; Humans; Infant, Newborn; Intraoperative Peri | 1994 |
Ketorolac versus acetaminophen or ibuprofen in controlling postoperative pain in patients with strabismus.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory A | 1994 |
Painless dental extraction in children.
Topics: Acetaminophen; Administration, Rectal; Administration, Topical; Child; Child, Preschool; Day Care, M | 1993 |
The efficacy of preoperative analgesic administration for postoperative pain management of pediatric dental patients.
Topics: Acetaminophen; Analysis of Variance; Anesthesia, Dental; Chi-Square Distribution; Child; Child Behav | 1993 |
Ketoprofen, acetaminophen plus oxycodone, and acetaminophen in the relief of postoperative pain.
Topics: Acetaminophen; Adult; Analysis of Variance; Cesarean Section; Dose-Response Relationship, Drug; Doub | 1993 |
Preoperative local infiltration with ropivacaine for postoperative pain relief after cholecystectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Amides; Analgesia; Anesthesia, Local; Anesthetics, Local; Bl | 1994 |
[Analgesic efficacy and the tolerance for piroxicam-beta-cyclodextrin compared to piroxicam, paracetamol and placebo in the treatment of postextraction dental pain].
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; beta-Cyclodextrins; Cyclo | 1993 |
Using memory for pain in analgesic research.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Codeine; Double-Blind Method; Female; Humans; Male; Men | 1993 |
The effect of post-operative instructions on recovery after tonsillectomy and adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Child; Child, Preschool; Diet Therapy; Female; Hemorrhage; | 1993 |
Prophylactic paracetamol for analgesia after vaginal termination of pregnancy.
Topics: Abortion, Induced; Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Anesthesia, | 1993 |
The efficacy of Na-naproxen after diagnostic and therapeutic arthroscopy of the knee joint.
Topics: Acetaminophen; Adult; Arthroscopy; Double-Blind Method; Female; Humans; Knee Joint; Male; Naproxen; | 1993 |
Effect of intravenous diclofenac on pain and recovery profile after day-case laparoscopy.
Topics: Acetaminophen; Adult; Ambulatory Care; Diclofenac; Double-Blind Method; Female; Fentanyl; Humans; In | 1993 |
[The drug treatment of postoperative pain].
Topics: Acetaminophen; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Me | 1993 |
[The treatment of postoperative pain in obstetrical-gynecologic surgery. A comparative study between ST-679 and paracetamol].
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroida | 1993 |
[An evaluation of the analgesic activity and tolerance of ST-679 in patients with pain following orthopedic and traumatological interventions].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Drug Tolerance; | 1993 |
Ketorolac and diclofenac for postoperative pain relief following oral surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Analgesics; Anti-Inflammatory Agents, | 1993 |
Preoperative diclofenac sodium reduces post-laparoscopy pain.
Topics: Acetaminophen; Administration, Rectal; Adult; Diclofenac; Double-Blind Method; Female; Genitalia, Fe | 1993 |
[Efficacy of propacetamol in postoperative pain based on two modes of intravenous administration].
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics; Breast Neoplasms; Female; Humans; I | 1995 |
A double-blind placebo-controlled study to assess the efficacy of a compound analgesic to prevent postoperative pain following oral surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; | 1996 |
A comparison of 2 analgesic regimens for the control of postoperative periodontal discomfort.
Topics: Acetaminophen; Administration, Oral; Adult; Alveolectomy; Analgesics, Non-Narcotic; Analgesics, Opio | 1996 |
Preoperative wound infiltration with bupivacaine reduces early and late opioid requirement after hysterectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-I | 1996 |
[Comparative study of buprenorphine and its combination to ketoprofen or propacetamol for postoperative analgesia in urologic surgery].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Buprenorphine; Drug Therapy, Combination; | 1996 |
Additive analgesic effect of codeine and paracetamol can be detected in strong, but not moderate, pain after Caesarean section. Baseline pain-intensity is a determinant of assay-sensitivity in a postoperative analgesic trial.
Topics: Acetaminophen; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Codeine; Double-Blind Method; Drug | 1996 |
The efficacy of ketoprofen and paracetamol (acetaminophen) in postoperative pain after third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Double-Blin | 1996 |
Post-operative pain relief in children following extraction of carious deciduous teeth under general anaesthesia: a comparison of nalbuphine and diclofenac.
Topics: Acetaminophen; Administration, Rectal; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Ana | 1996 |
Analgesic efficacy of controlled-release oxycodone in postoperative pain.
Topics: Acetaminophen; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; | 1996 |
Analgesic efficacy of the kappa-receptor agonist, enadoline, in dental surgery pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Benzofurans; Codeine; Double-Bli | 1996 |
Analgesic efficacy of enadoline versus placebo or morphine in postsurgical pain.
Topics: Abdomen; Acetaminophen; Adult; Analgesia; Analgesia, Obstetrical; Analgesics, Opioid; Benzofurans; C | 1996 |
Morphine consumption in patients receiving rectal paracetamol and diclofenac alone and in combination.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anti-Inflammatory Age | 1996 |
Comparison of tenoxicam by intramuscular injection or wound infiltration for analgesia after inguinal herniorrhaphy.
Topics: Abdomen; Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Non-Narcotic; Analges | 1996 |
Analgesic efficacy of paracetamol in children using tonsillectomy as a pain model.
Topics: Acetaminophen; Administration, Oral; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Nar | 1996 |
The effect of tramadol on dento-alveolar surgical pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Alveolectomy; Analgesics, Non-Narcotic; A | 1997 |
Analgesia following arthroscopy--a comparison of intra-articular morphine, pethidine and fentanyl.
Topics: Acetaminophen; Adult; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; | 1997 |
Comparison of the analgesic effects of diflunisal and paracetamol in the treatment of postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 1996 |
Comparison of the efficacy of paracetamol versus paracetamol, codeine and promethazine (Painstop) for premedication and analgesia for myringotomy in children.
Topics: Acetaminophen; Analgesia; Analgesics; Child; Child, Preschool; Codeine; Double-Blind Method; Drug Co | 1997 |
Comparison of postoperative emesis, recovery profile, and analgesia in pediatric strabismus repair. Rectal acetaminophen versus intravenous fentanyl-droperidol.
Topics: Acetaminophen; Administration, Rectal; Analgesia; Analgesics; Anesthesia Recovery Period; Child; Chi | 1997 |
A prospective, randomized, double-masked trial to evaluate the role of topical anesthetics in controlling pain after photorefractive keratectomy.
Topics: Acetaminophen; Administration, Topical; Adult; Aged; Anesthetics, Local; Cornea; Dextropropoxyphene; | 1995 |
Postoperative analgesia with i.v. propacetamol and ketoprofen combination after disc surgery.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; Female; Hu | 1997 |
Acetaminophen or ketorolac for post myringotomy pain in children? A prospective, double-blinded comparison.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Child; Child, Preschool; Double-Blind | 1997 |
Effect of preemptive acetaminophen on postoperative pain scores and oral fluid intake in pediatric tonsillectomy patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Humans; Infant; Male; Pain | 1996 |
A comparison of oral ketorolac and hydrocodone-acetaminophen for analgesia after ambulatory surgery: arthroscopy versus laparoscopic tubal ligation.
Topics: Acetaminophen; Administration, Oral; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic | 1997 |
Are the pharmacokinetics of ibuprofen important determinants for the drug's efficacy in postoperative pain after third molar surgery?
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non- | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
A comparison of ibuprofen versus acetaminophen with codeine in the young tonsillectomy patient.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 1997 |
Analgesia after day case laparoscopic sterilisation. A comparison of tramadol with paracetamol/dextropropoxyphene and paracetamol/codeine combinations.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesia; Analgesics, Opioid; Codeine; Dextro | 1997 |
Postoperative analgesia with preoperative oral ibuprofen or acetaminophen in children undergoing myringotomy.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 1997 |
A comparison of etodolac (Ultradol) with acetaminophen plus codeine (Tylenol #3) in controlling post-surgical pain in vasectomy patients.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; | 1997 |
The analgesic efficacy of an injectable prodrug of acetaminophen in children after orthopaedic surgery.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Bones of Upper Extremity; Child; Double-Blind M | 1997 |
Pattern of self-administered paracetamol and codeine analgesic consumption after mandibular third-molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Drug Combin | 1997 |
Comparison of caudal block using bupivacaine and ketamine with ilioinguinal nerve block for orchidopexy in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Caudal; Anesthesia, General; Anesthetics, Combi | 1997 |
A pilot study comparing ketoprofen and acetaminophen with hydrocodone for the relief of postoperative periodontal discomfort.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anti-Inflammatory A | 1997 |
Lysine clonixinate vs. paracetamol/codeine in postepisiotomy pain.
Topics: Acetaminophen; Adult; Analgesics; Analysis of Variance; Clonixin; Codeine; Double-Blind Method; Epis | 1998 |
Comparison of the safety and efficacy of a combination analgesic Myprodol and Ponstan in the treatment of dental pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 1992 |
Continuous-flow cold therapy for outpatient anterior cruciate ligament reconstruction.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anterior Cruci | 1998 |
[Comparison of propacetamol and morphine in postoperative analgesia].
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; Humans; Infusions | 1998 |
Efficacy of propacetamol in the treatment of postoperative pain. Morphine-sparing effect in orthopedic surgery. Italian Collaborative Group on Propacetamol.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioi | 1998 |
Analgesic efficacy and safety of (R)- ketoprofen in postoperative dental pain.
Topics: Acetaminophen; Adult; Analgesics; Dose-Response Relationship, Drug; Double-Blind Method; Drug Admini | 1998 |
Clinical effects of diflunisal and paracetamol in impacted mandibular third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 1997 |
Examination of acetaminophen for outpatient management of postoperative pain in children.
Topics: Acetaminophen; Administration, Oral; Administration, Rectal; Adolescent; Ambulatory Care; Analgesics | 1998 |
Efficacy and tolerance of lysine clonixinate versus paracetamol/codeine following inguinal hernioplasty.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Clonixin; Codeine; Double-Blind Method | 1998 |
Analgesic efficacy and safety of preoperative versus postoperative ketorolac in paediatric tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 1998 |
Acetaminophen as an adjunct to morphine by patient-controlled analgesia in the management of acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Administration, Oral; Adolescent; Adult; Aged; Analgesia, Patient-Cont | 1998 |
Variation in surgical trauma and baseline pain intensity: effects on assay sensitivity of an analgesic trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; | 1998 |
Relative bioavailability and plasma paracetamol profiles of Panadol suppositories in children.
Topics: Acetaminophen; Administration, Oral; Administration, Rectal; Analgesics, Non-Narcotic; Biological Av | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Ibuprofen for tonsillectomy pain in children: efficacy and complications.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 1998 |
Improved postoperative analgesia with isoflurane than with propofol anaesthesia.
Topics: Abdomen; Acetaminophen; Adult; Analgesia; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; A | 1998 |
Patient-controlled analgesia with oxycodone in the treatment of postcraniotomy pain.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inf | 1999 |
Determination of an effective dose of intrathecal morphine for pain relief after cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient | 1999 |
Determination of an effective dose of intrathecal morphine for pain relief after cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient | 1999 |
Determination of an effective dose of intrathecal morphine for pain relief after cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient | 1999 |
Determination of an effective dose of intrathecal morphine for pain relief after cesarean delivery.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesia, Obstetrical; Analgesia, Patient | 1999 |
The effectiveness of clonidine as an analgesic in paediatric adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Analgesics; Analgesics, Non-Narcotic; Analgesics | 1998 |
A double-blinded evaluation of propacetamol versus ketorolac in combination with patient-controlled analgesia morphine: analgesic efficacy and tolerability after gynecologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia; Analgesia, Patient-Controlled; Analgesics; Analge | 1999 |
Oral granisetron for strabismus surgery in children.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anesthetics, Inhalation; Antiemetics; | 1999 |
Paracetamol 1 g given rectally at the end of minor gynaecological surgery is not efficacious in reducing postoperative pain.
Topics: Abortion, Induced; Acetaminophen; Administration, Rectal; Adult; Analgesics, Non-Narcotic; Anesthesi | 1999 |
Intra-articular morphine for pain relief after knee arthroscopy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; | 1999 |
Preoperative oral dextromethorphan does not reduce pain or analgesic consumption in children after adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Analgesia; Analgesics; Anesthesia Recovery Perio | 1999 |
Tenoxicam and paracetamol-codeine combination after oral surgery: a prospective, randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Co | 1998 |
The analgesic effect of preoperative administration of propacetamol, tenoxicam or a mixture of both in arthroscopic, outpatient knee surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Anesthetics, Intravenous; An | 1999 |
Morphine-sparing effect of acetaminophen in pediatric day-case surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; | 1999 |
Oral tramadol: analgesic efficacy in children following multiple dental extractions.
Topics: Acetaminophen; Administration, Oral; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analg | 1999 |
Tramadol suppositories are less suitable for post-operative pain relief than rectal acetaminophen/codeine.
Topics: Acetaminophen; Administration, Rectal; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Co | 1999 |
Patient-controlled analgesia in postoperative cardiac surgery.
Topics: Acetaminophen; Administration, Oral; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analge | 1999 |
Analgesic efficacy of paracetamol and diclofenac in children receiving PCA morphine.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 1999 |
Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 1999 |
Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 1999 |
Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 1999 |
Combining diclofenac with acetaminophen or acetaminophen-codeine after oral surgery: a randomized, double-blind single-dose study.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 1999 |
Rectal paracetamol has a significant morphine-sparing effect after hysterectomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anti-Infla | 1999 |
Is routine procaine spirit application necessary in the care of episiotomy wound?
Topics: Acetaminophen; Administration, Cutaneous; Adult; Analgesics, Non-Narcotic; Anesthetics, Local; Baths | 1999 |
Pharmacokinetics of paracetamol in adults after cardiac surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Biological Availability; Cardi | 1999 |
The pharmacokinetics and analgesic efficacy of larger dose rectal acetaminophen (40 mg/kg) in adults: a double-blinded, randomized study.
Topics: Acetaminophen; Administration, Rectal; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inf | 2000 |
The effect of ketamine on 0.25% and 0.125% bupivacaine for caudal epidural blockade in children.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Anesthesia Recovery Period | 1999 |
Diclofenac or acetaminophen for analgesia in paediatric tonsillectomy outpatients.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Child; | 2000 |
A comparison of rectal and intramuscular codeine phosphate in children following neurosurgery.
Topics: Absorption; Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Analgesics, Opioid; Ana | 2000 |
Time to onset of analgesia and analgesic efficacy of effervescent acetaminophen 1000 mg compared to tablet acetaminophen 1000 mg in postoperative dental pain: a single-dose, double-blind, randomized, placebo-controlled study.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Analgesics, Non-Narcotic; Double-Blind Method; Dry Sock | 2000 |
The effect of paracetamol, fentanyl, and systematic assessments on children's pain after tonsillectomy and adenoidectomy.
Topics: Acetaminophen; Adenoidectomy; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, | 1999 |
Single-dose vicoprofen compared with acetaminophen with codeine and placebo in patients with acute postoperative pain after third molar extractions.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Analysis of Variance; Chi-Square Distribution; Codeine | 2000 |
Behavioural measurement of postoperative pain after oral surgery.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Alveolectomy; Analgesia; Analgesics; Analgesics, No | 2000 |
Combination hydrocodone and ibuprofen versus combination oxycodone and acetaminophen in the treatment of postoperative obstetric or gynecologic pain.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analge | 2000 |
No effect of preoperative paracetamol and codeine suppositories for pain after termination of pregnancies in general anaesthesia.
Topics: Abortion, Induced; Acetaminophen; Adult; Alfentanil; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2000 |
Comparison of intravenous patient-controlled analgesia with tramadol versus morphine after microvascular breast reconstruction.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthes | 2000 |
Randomised, placebo-controlled study of the postoperative analgesic effects of ketoprofen after spinal fusion surgery.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Age | 2000 |
A comparison of superficial versus combined (superficial and deep) cervical plexus block for carotid endarterectomy: a prospective, randomized study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2000 |
Double-blind randomized study of tramadol vs. paracetamol in analgesia after day-case tonsillectomy in children.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; | 2000 |
Acetaminophen versus acetaminophen with codeine after pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Doubl | 2000 |
Acetaminophen versus acetaminophen with codeine after pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Doubl | 2000 |
Acetaminophen versus acetaminophen with codeine after pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Doubl | 2000 |
Acetaminophen versus acetaminophen with codeine after pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Codeine; Doubl | 2000 |
Pain control after routine dento-alveolar day surgery: a patient satisfaction survey.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Dental Audi | 2000 |
Effect of multifaceted intervention promoting early switch from intravenous to oral acetaminophen for postoperative pain: controlled, prospective, before and after study.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Decis | 2000 |
Ibuprofen liquigel for oral surgery pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Dose-Response Relationshi | 2000 |
Preoperative rectal diclofenac versus paracetamol for tonsillectomy: effects on pain and blood loss.
Topics: Acetaminophen; Administration, Rectal; Adult; Analgesics, Non-Narcotic; Anesthesia; Anti-Inflammator | 2001 |
Postoperative analgesia at home after ambulatory hand surgery: a controlled comparison of tramadol, metamizol, and paracetamol.
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics; Dipyrone; Double-Blind Metho | 2001 |
Pharmacokinetics of oral diclofenac and acetaminophen in children after surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, | 2001 |
[Postoperative pain and surgical treatment of trapeziometacarpal osteoarthritis of the thumb after ambulatory surgery].
Topics: Acetaminophen; Aged; Ambulatory Surgical Procedures; Analgesics; Anti-Inflammatory Agents, Non-Stero | 2000 |
Prophylactically-administered rectal acetaminophen does not reduce postoperative opioid requirements in infants and small children undergoing elective cleft palate repair.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia; Cle | 2001 |
Intravenous ketoprofen in thyroid and parathyroid surgery.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2001 |
Efficacy and tolerability of celecoxib versus hydrocodone/acetaminophen in the treatment of pain after ambulatory orthopedic surgery in adults.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2001 |
Patient-controlled epidural analgesia versus continuous epidural analgesia after total knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesi | 2001 |
Intravenous tramadol compared to propacetamol for postoperative analgesia following thyroidectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Analgesics, Opioid; Double-Blind Method; Female; | 2001 |
Oral ibuprofen versus paracetamol plus codeine for analgesia after ambulatory surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2001 |
Intravenous administration of propacetamol reduces morphine consumption after spinal fusion surgery.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2001 |
Intravenous administration of propacetamol reduces morphine consumption after spinal fusion surgery.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2001 |
Intravenous administration of propacetamol reduces morphine consumption after spinal fusion surgery.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2001 |
Intravenous administration of propacetamol reduces morphine consumption after spinal fusion surgery.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2001 |
Propacetamol versus ketorolac for treatment of acute postoperative pain after total hip or knee replacement.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Arthroplasty, Replacem | 2001 |
Analgesic efficacy and safety of nefopam vs. propacetamol following hepatic resection.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Ana | 2001 |
Effect of apical trephination on postoperative pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Anti-Infla | 2001 |
Effect of prophylactic amoxicillin on endodontic flare-up in asymptomatic, necrotic teeth.
Topics: Acetaminophen; Adult; Amoxicillin; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Varianc | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Effect of penicillin on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Infla | 2001 |
Pain control with paracetamol from a sustained release formulation and a standard release formulation after third molar surgery: a randomised controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Delayed-Action Preparations; Double-Blin | 2001 |
Rofecoxib versus codeine/acetaminophen in postoperative dental pain: a double-blind, randomized, placebo- and active comparator-controlled clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blin | 2001 |
Onset of analgesia for liquigel ibuprofen 400 mg, acetaminophen 1000 mg, ketoprofen 25 mg, and placebo in the treatment of postoperative dental pain.
Topics: Abdominal Pain; Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory | 2001 |
Acetaminophen analgesia in children: placebo effect and pain resolution after tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Humans; Male; | 2001 |
The effectiveness of an anesthetic continuous-infusion device on postoperative pain control.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Non-Nar | 2002 |
The effect of ketoprofen on recovery after tonsillectomy in children: a 3-week follow-up study.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2002 |
Recovery after tonsillectomy in adults: a three-week follow-up study.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Adolescent; Adult; Aged; Codeine; Drug Therapy, | 2002 |
Efficacy of nimesulide in pain relief after day care surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2002 |
Effect of peri- and postoperative epidural anaesthesia on pain and gastrointestinal function after abdominal hysterectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Ep | 2001 |
Double-blind, placebo-controlled analgesic study of ibuprofen or rofecoxib in combination with paracetamol for tonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-St | 2002 |
Postoperative pain management after supratentorial craniotomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe | 2002 |
Postoperative pain management after supratentorial craniotomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe | 2002 |
Postoperative pain management after supratentorial craniotomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe | 2002 |
Postoperative pain management after supratentorial craniotomy.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Intravenous; Anesthe | 2002 |
Diclofenac or paracetamol for analgesia in paediatric myringotomy outpatients.
Topics: Acetaminophen; Administration, Oral; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anti- | 2002 |
The efficacy of premedication with celecoxib and acetaminophen in preventing pain after otolaryngologic surgery.
Topics: Acetaminophen; Adenoids; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents | 2002 |
The analgesic efficacy of valdecoxib vs. oxycodone/acetaminophen after oral surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Consumer P | 2002 |
Effective pain relief: comparative results with acetaminophen in a new dose formulation, propoxyphene napsylate-acetaminophen combination, and placebo.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Dextropropoxyphene; Dosage Forms; Dose-R | 1976 |
Pulsed electromagnetic energy therapy in third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Edema; Electromagnetic Phenomena; Female; Hum | 1978 |
A comparison of analgesic effectiveness of oral butorphanol/acetaminophen, oxycodone/acetaminophen and placebo in hospitalized postsurgical patients.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics; Butorphanol; Codeine; Double-Blind Met | 1979 |
A double-blind comparative evaluation of aspirin, paracetamol and paracetamol + caffeine (finimal) for their analgesic effectiveness.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Caffeine; Clinical Trials as Topic; Drug Therapy, C | 1977 |
Acetylsalicylic acid vs paracetamol: effects on post-operative course.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Clinical Trials as Topic; Female; Hemorrhage; Humans; Mal | 1977 |
Analgesia following oral surgery for day patients: a clincial comparison of two analgesics.
Topics: Acetaminophen; Adult; Analgesics; Clinical Trials as Topic; Dextropropoxyphene; Drug Combinations; F | 1977 |
Diflunisal in post-episiotomy pain: a preliminary report of a double-blind comparative study.
Topics: Acetaminophen; Analgesics; Biphenyl Compounds; Clinical Trials as Topic; Dextropropoxyphene; Double- | 1978 |
Comparative assessment of fenoprofen and paracetamol given in combination for pain after surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, | 1978 |
Paracetamol versus placebo: effects on post-operative course.
Topics: Acetaminophen; Adult; Body Temperature; Clinical Trials as Topic; Double-Blind Method; Female; Human | 1979 |
Analgesic combinations with orphenadrine in oral post-surgical pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Clinical Trials as Topic; Double-Blind Method; D | 1979 |
Butorphanol/acetaminophen double-blind study in postoperative pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Analgesics; Butorphanol; Child; Clinic | 1979 |
A model to evaluate mild analgesics in oral surgery outpatients.
Topics: Acetaminophen; Adolescent; Adult; Ambulatory Care; Analgesics; Aspirin; Clinical Trials as Topic; Co | 1976 |
Effect of paracetamol, mephenoxalone and their combination on pain following bone surgery.
Topics: Acetaminophen; Bone and Bones; Clinical Trials as Topic; Drug Administration Schedule; Drug Synergis | 1976 |
[Clinical experimentation of an analgesic in dental surgery].
Topics: Acetaminophen; Adolescent; Adult; Anesthesia, Dental; Ascorbic Acid; Child; Clinical Trials as Topic | 1976 |
Relief of severe pain with acetaminophen in a new dose formulation versus propoxyphene hydrochloride 65 mg. and placebo: a comparative double-blind study.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Dextropropoxyphene; Episiotomy; Female; | 1975 |
The analgesic effect of Syndol following neurosurgery and neurosurgical procedures.
Topics: Acetaminophen; Adult; Caffeine; Clinical Trials as Topic; Codeine; Doxylamine; Drug Combinations; Fe | 1975 |
Tenoxicam for pain relief following third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Fema | 1992 |
Analgesic oral efficacy of tramadol hydrochloride in postoperative pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics; Cesarean Section; Dextropropoxyp | 1992 |
[Analgesic effect of ibuprofen in pain after episiotomy].
Topics: Acetaminophen; Adult; Double-Blind Method; Drug Evaluation; Episiotomy; Female; Humans; Ibuprofen; P | 1992 |
Lignocaine vs bupivacaine in prominent ear correction: a controlled trial.
Topics: Acetaminophen; Adolescent; Adult; Anesthesia, General; Anesthesia, Local; Bupivacaine; Child; Child, | 1992 |
Pain control after third molar surgery--a comparative study of ibuprofen (Ibumetin) and a paracetamol/codeine combination (Citodon).
Topics: Acetaminophen; Adolescent; Adult; Codeine; Drug Combinations; Edema; Female; Humans; Ibuprofen; Male | 1992 |
A multiple dose comparison of combinations of ibuprofen and codeine and paracetamol, codeine and caffeine after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adult; Caffeine; Codeine; Double-Blind Method; Drug Combination | 1992 |
The efficacy of locally applied aspirin and acetaminophen in postoperative pain after third molar surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aspirin; Double-Blind Method; Gels; Humans; | 1992 |
Effect of combined prednisolone, epidural analgesia, and indomethacin on the systemic response after colonic surgery.
Topics: Acetaminophen; Activities of Daily Living; Aged; Analgesia, Epidural; Body Temperature; Bupivacaine; | 1992 |
Application of sublingual buprenorphine in combination with naproxen or paracetamol for post-operative pain relief in cholecystectomy patients in a double-blind study.
Topics: Acetaminophen; Administration, Sublingual; Adult; Aged; Analgesia, Patient-Controlled; Buprenorphine | 1992 |
[Prevention and control of pain in (adeno)tonsillectomy].
Topics: Acetaminophen; Adenoidectomy; Child; Child, Preschool; Codeine; Drug Combinations; Humans; Pain Meas | 1992 |
Treatment of postoperative pain with diclofenac in uvulopalatopharyngoplasty.
Topics: Acetaminophen; Adult; Bleeding Time; Diclofenac; Double-Blind Method; Female; Humans; Male; Middle A | 1992 |
Analgesic efficacy of acetaminophen 1000 mg, acetaminophen 2000 mg, and the combination of acetaminophen 1000 mg and codeine phosphate 60 mg versus placebo in acute postoperative pain.
Topics: Acetaminophen; Adult; Analgesia; Codeine; Double-Blind Method; Drug Therapy, Combination; Female; Hu | 1991 |
Analgesia in tonsillectomy: a double-blind study on pre and post-operative treatment with diclofenac.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Diclofenac; Double-Blind Method; Female; Humans; Male; | 1991 |
[Efficacy and tolerance of tiaprofenic acid for extraction complications. Results of a randomized double-blind study, tiaprofenic acid versus paracetamol].
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Humans; Molar, T | 1991 |
Day case laparoscopy: a survey of postoperative pain and an assessment of the value of diclofenac.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Dextropropoxyphene; Diclofenac; Drug Combinati | 1991 |
Intrapleural bupivacaine analgesia after thoraco-abdominal incision for oesophagectomy.
Topics: Abdomen; Acetaminophen; Analgesia; Bupivacaine; Chest Tubes; Double-Blind Method; Esophagus; Female; | 1991 |
Third molar surgery: the effect of primary closure, wound dressing and metronidazole on postoperative recovery.
Topics: Acetaminophen; Adult; Analgesics; Bandages; Bismuth; Caffeine; Codeine; Drug Combinations; Female; H | 1991 |
The analgesic efficacy of flurbiprofen compared to acetaminophen with codeine.
Topics: Acetaminophen; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Chi-Square Dist | 1991 |
Comparison of postpartum pain treatments using a sequential trial design. I. Paracetamol versus placebo.
Topics: Acetaminophen; Adult; Episiotomy; Female; Humans; Pain Measurement; Pain, Postoperative; Placebos; P | 1991 |
Evaluation of ketorolac, aspirin, and an acetaminophen-codeine combination in postoperative oral surgery pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Asp | 1990 |
Evaluation of ketorolac, ibuprofen, acetaminophen, and an acetaminophen-codeine combination in postoperative oral surgery pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesia; Anti-Inflammatory Agents, Non-Ste | 1990 |
Etodolac: analgesic effects in musculoskeletal and postoperative pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Gouty; Aspirin; Athletic Injuries | 1990 |
Multicenter clinical trial of ibuprofen and acetaminophen in the treatment of postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Male; Middle Aged; | 1990 |
Pharmacokinetics of paracetamol after cardiac surgery.
Topics: Acetaminophen; Administration, Rectal; Cardiac Surgical Procedures; Child; Child, Preschool; Fever; | 1990 |
A study of the comparative efficacy of four common analgesics in the control of postsurgical dental pain.
Topics: Acetaminophen; Adult; Analgesics; Analysis of Variance; Aspirin; Caffeine; Codeine; Drug Combination | 1990 |
Preoperative piroxicam for postoperative analgesia in dental surgery.
Topics: Acetaminophen; Adult; Anesthesia Recovery Period; Anesthesia, Dental; Female; Humans; Male; Opium; P | 1990 |
[The efficacy of paracetamol (Tylenol) and acetyl salicylic acid (Aspirin) in treating postoperative pain].
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Double-Blind Method; Female; Humans; Male; Middle A | 1990 |
[Double blind biometric study on postoperative effects of analgesics].
Topics: Acetaminophen; Adult; Codeine; Double-Blind Method; Drug Combinations; Female; Humans; Male; Molar, | 1990 |
Analgesic efficacy of flurbiprofen as compared to acetaminophen and placebo after periodontal surgery.
Topics: Acetaminophen; Adult; Double-Blind Method; Female; Flurbiprofen; Humans; Male; Middle Aged; Pain Mea | 1990 |
Bromfenac, acetaminophen, and placebo in orthopedic postoperative pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Benzophenones; Bromobenzenes; Female; Humans; Ma | 1990 |
A comparison of four analgesics in post-episiotomy pain.
Topics: Acetaminophen; Analgesics; Aspirin; Dipyrone; Episiotomy; Female; Humans; Ibuprofen; Pain, Postopera | 1990 |
Comparison of flurbiprofen and acetaminophen with codeine in postoperative foot pain.
Topics: Acetaminophen; Adolescent; Codeine; Double-Blind Method; Drug Therapy, Combination; Flurbiprofen; Fo | 1990 |
A comparison of paracetamol and diflunisal for pain control following 3rd molar surgery.
Topics: Acetaminophen; Adult; Diflunisal; Double-Blind Method; Female; Humans; Male; Molar, Third; Pain, Pos | 1989 |
The efficacy of benorylate in postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Female; Humans; Male; Molar, Third; Pain, Pos | 1989 |
Augmentation of acetaminophen analgesia by the antihistamine phenyltoloxamine.
Topics: Acetaminophen; Adolescent; Adult; Benzhydryl Compounds; Double-Blind Method; Drug Synergism; Drug Th | 1989 |
Evaluation of the analgesic activity and tolerability of aceclofenac in the treatment of post-episiotomy pain.
Topics: Acetaminophen; Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; | 1989 |
Ibuprofen and acetaminophen in the relief of postpartum episiotomy pain.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Episiotomy; Female; | 1989 |
[Postoperative analgesia with morphine versus morphine and paracetamol. A double-blind clinically controlled study with a placebo].
Topics: Acetaminophen; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Female; Hip | 1989 |
Ibuprofen and acetaminophen in the relief of acute pain: a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Double-Blind Method; Female; Humans; Ibuprofen; Mal | 1989 |
Evaluation of flurbiprofen, acetaminophen, an acetaminophen-codeine combination, and placebo in postoperative oral surgery pain.
Topics: Acetaminophen; Adolescent; Adult; Codeine; Double-Blind Method; Drug Combinations; Drug Evaluation; | 1989 |
Postoperative pain relief with pentazocine and acetaminophen: comparison with other analgesic combinations and placebo.
Topics: Acetaminophen; Clinical Trials as Topic; Codeine; Dextropropoxyphene; Drug Combinations; Female; Hum | 1985 |
Pain relief after arthroscopy: naproxen sodium compared to propoxyphene napsylate with acetaminophen.
Topics: Acetaminophen; Adolescent; Adult; Arthroscopy; Clinical Trials as Topic; Dextropropoxyphene; Double- | 1987 |
[Clinical evaluation of analgesics in surgical patients in the postoperative period].
Topics: Acetaminophen; Adult; Aged; Anesthesia; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind M | 1987 |
[Measurement of pain intensity in surgery patients for the purpose of evaluating the effects of analgesics].
Topics: Acetaminophen; Adult; Aged; Clinical Trials as Topic; Dextropropoxyphene; Double-Blind Method; Femal | 1988 |
Flurbiprofen for the treatment of soft tissue trauma.
Topics: Acetaminophen; Aspirin; Back Pain; Flurbiprofen; Humans; Knee; Leg Injuries; Ligaments, Articular; P | 1986 |
Aceclofenac and paracetamol in episiotomal pain.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Diclofenac; Double | 1988 |
Double-blind parallel comparison of ketoprofen (Orudis), acetaminophen plus codeine, and placebo in postoperative pain.
Topics: Acetaminophen; Adult; Aged; Clinical Trials as Topic; Codeine; Double-Blind Method; Female; Humans; | 1988 |
Suprofen versus paracetamol after oral surgery.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Double-Blind Method; Female; Humans; Mal | 1987 |
Postoperative pain control for outpatient oral surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Codeine; Diflunisa | 1987 |
Paracetamol and diflunisal for pain relief following third molar surgery in Hong Kong Chinese.
Topics: Acetaminophen; Adult; China; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hong | 1987 |
Double-blind comparison of meclofenamate sodium with acetaminophen, acetaminophen with codeine and placebo for relief of postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Codeine; Double-Blind Method; Female; Humans; Male; Meclofenamic A | 1988 |
Flupirtine: the first Italian experience.
Topics: Acetaminophen; Aminopyridines; Analgesics; Athletic Injuries; Clinical Trials as Topic; Episiotomy; | 1987 |
Clinical experience with flupirtine in the U.S.
Topics: Acetaminophen; Aminopyridines; Analgesics; Clinical Trials as Topic; Double-Blind Method; Drug Thera | 1987 |
Pharmacokinetics and clinical efficacy of intrarectal solution of acetaminophen.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Child; Child, Preschool; Double-Blind Method; | 1988 |
Post-tonsillectomy haemorrhage and analgesics. A comparative study of acetylsalicylic acid and paracetamol.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Child; Child, Preschool; Female; Hemorrhage; Hemostasis, | 1988 |
Analgesic regimens for third molar surgery: pharmacologic and behavioral considerations.
Topics: Acetaminophen; Adolescent; Adult; Drug Administration Schedule; Female; Humans; Male; Middle Aged; M | 1986 |
Effect of pretreatment with acetaminophen-propoxyphene for oral surgery pain.
Topics: Acetaminophen; Adolescent; Adult; Dextropropoxyphene; Double-Blind Method; Drug Administration Sched | 1987 |
RF 46-790 versus paracetamol: effect on post-operative pain.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; | 1986 |
Ketorolac and acetaminophen for orthopedic postoperative pain.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analysis of Variance; Clinical Trials as Topic; Do | 1986 |
Comparison of oral nalbuphine, acetaminophen, and their combination in postoperative pain.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Clinical Trials as Topic; Double-Blind | 1986 |
The effects of indoprofen vs paracetamol on swelling, pain and other events after surgery.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Female; Hemorrhage; Humans; Indoprofen; | 1986 |
Suppression of dental pain by the preoperative administration of flurbiprofen.
Topics: Acetaminophen; Clinical Trials as Topic; Double-Blind Method; Drug Therapy, Combination; Etidocaine; | 1986 |
Comparative study of flurbiprofen, zomepirac sodium, acetaminophen plus codeine, and acetaminophen for the relief of postsurgical dental pain.
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Codeine; Double-Blind Method; Drug Evaluation; Drug | 1986 |
The additive analgesic efficacy of acetaminophen, 1000 mg, and codeine, 60 mg, in dental pain.
Topics: Acetaminophen; Adult; Codeine; Drug Synergism; Drug Therapy, Combination; Female; Humans; Male; Pain | 1987 |
Epidural morphine: a new approach to combined anesthesia and analgesia in urological patients.
Topics: Acetaminophen; Aged; Analgesia; Anesthesia, Epidural; Bupivacaine; Epinephrine; Humans; Male; Middle | 1986 |
Analgesic and gastrointestinal effects of nalbuphine--a comparison with pethidine.
Topics: Absorption; Acetaminophen; Adult; Animals; Double-Blind Method; Drug Evaluation; Female; Gastric Emp | 1986 |
A new paracetamol/paracetamol-methionine ester combination effects on postoperative course.
Topics: Acetaminophen; Adolescent; Adult; Body Temperature; Drug Therapy, Combination; Female; Humans; Male; | 1986 |
Comparison of meclofenamate sodium with buffered aspirin and placebo in the treatment of postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aspirin; Codeine; Female; Humans; Male; Meclofenamic Acid; M | 1985 |
Analgesics for pain relief after gynaecological surgery. A two-phase study.
Topics: Acetaminophen; Administration, Oral; Adult; Analgesics; Benzophenones; Caffeine; Clinical Trials as | 1985 |
Multiple doses of paracetamol plus codeine taken immediately after oral surgery.
Topics: Acetaminophen; Adult; Clinical Trials as Topic; Codeine; Dose-Response Relationship, Drug; Double-Bl | 1985 |
Suprofen compared to dextropropoxyphene hydrochloride and paracetamol (Cosalgesic) after extraction of wisdom teeth under general anaesthesia.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anesthesia, Dental; Anesthes | 1985 |
Postextraction pain relief in children: a clinical trial of liquid analgesics.
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Clinical Trials as Topic; Codeine; Double-Blind | 1985 |
Effects of doxylamine and acetaminophen on postoperative sleep.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Aged; Double-Blind Method; Doxylamine; Drug | 1985 |
Efficacy and quality of ibuprofen and acetaminophen plus codeine analgesia.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Codeine; Drug Combinations; Drug Evaluation; Emo | 1985 |
Comparison of paracetamol and aminophenazone plus diazepam suppositories for anxiety and pain relief after tonsillectomy in children.
Topics: Acetaminophen; Aminopyrine; Anxiety; Child; Child, Preschool; Diazepam; Drug Combinations; Female; H | 1985 |
Acetaminophen with codeine for the relief of severe pain in postpartum patients.
Topics: Acetaminophen; Adolescent; Adult; Clinical Trials as Topic; Codeine; Drug Combinations; Drug Evaluat | 1974 |
542 other studies available for acetaminophen and Acute Post-operative Pain
| Article | Year |
|---|---|
[Respective indications of two analgesics].
Topics: Acetaminophen; Adolescent; Adult; Ascorbic Acid; Child; Drug Combinations; Drug Tolerance; Humans; M | 1981 |
[Intraoperative and postoperative analgesia in pediatric surgery. 1 years' experience].
Topics: Acetaminophen; Analgesia; Analgesics; Anesthesia, Epidural; Ascorbic Acid; Child; Codeine; Dextromor | 1990 |
Patient-Centered Decision-making for Postoperative Narcotic-Free Endocrine Surgery: A Randomized Clinical Trial.
Topics: Acetaminophen; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Op | 2021 |
An observational cohort study comparing ibuprofen and oxycodone in children with fractures.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Co | 2021 |
Comparison between the Effects of Loxoprofen and Acetaminophen on Postoperative Pain Following Radical Prostatectomy: A Propensity Score Matching Analysis.
Topics: Acetaminophen; Acute Kidney Injury; Aged; Anti-Inflammatory Agents, Non-Steroidal; Chemical and Drug | 2021 |
The efficacy of peritonsillar injection of bupivacaine vs intravenous acetaminophen on post-tonsillectomy pain in children.
Topics: Acetaminophen; Anesthetics, Local; Bupivacaine; Child; Humans; Pain, Postoperative; Tonsillectomy | 2022 |
Association of Intravenous Acetaminophen Administration With the Duration of Intravenous Opioid Use Among Hospitalized Pediatric Patients.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, | 2021 |
Sphenopalatine ganglion block for ipsilateral shoulder pain following open pancreaticoduodenectomy.
Topics: Acetaminophen; Female; Humans; Lidocaine; Middle Aged; Pain, Postoperative; Pancreaticoduodenectomy; | 2022 |
Decreasing Postoperative Opioid Prescriptions After Orthopedic Trauma Surgery: The "Lopioid" Protocol.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Gabapentin; Humans; Meloxicam; Morphine Derivatives; | 2022 |
Propacetamol in dogs: First description of its pharmacokinetics after intravenous and oral administration.
Topics: Acetaminophen; Administration, Oral; Animals; Cross-Over Studies; Dog Diseases; Dogs; Humans; Pain, | 2022 |
Perioperative use of pain medications in vaginal versus laparoscopic pelvic organ prolapse surgery.
Topics: Acetaminophen; Analgesics, Opioid; Female; Humans; Laparoscopy; Pain, Postoperative; Pelvic Organ Pr | 2022 |
The efficacy of laparoscopic transversus abdominis plane block on reducing postoperative narcotic usage in patients undergoing minimally invasive adrenalectomy.
Topics: Abdominal Muscles; Acetaminophen; Adrenalectomy; Analgesics, Opioid; Humans; Laparoscopy; Narcotics; | 2022 |
Comparison of Preoperative Intravenous and Oral Acetaminophen: Methodological Issues.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Pa | 2022 |
An Enhanced Recovery After Surgery protocol for robotic-assisted laparoscopic nephrectomies utilizing a quadratus lumborum block.
Topics: Acetaminophen; Analgesics, Opioid; Enhanced Recovery After Surgery; Gabapentin; Humans; Laparoscopy; | 2022 |
The NOpioid Project: a prospective observational feasibility study examining the implementation of a non-narcotic post-operative pain control regimen.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Appendectomy; Appendicitis; Feas | 2022 |
Perioperative Multimodal Pain Management Approach in Older Adults With Polytrauma.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Humans; Multiple Trauma; Opioid-Related Disorders; Pain Man | 2022 |
Liposomal Bupivacaine and Ropivacaine Adductor Canal Blocks for Anterior Cruciate Ligament Reconstruction Provide Similar Postoperative Analgesia.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Anesthetics, Local; Anterior Cruciate Ligament Reconst | 2023 |
Enhanced Recovery after Surgery Protocol to Improve Racial and Ethnic Disparities in Postcesarean Pain Management.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents; Celecoxib; Endrin; Enhanced | 2022 |
An Enhanced Recovery After Surgery Protocol Decreases the Use of Narcotics in Infrainguinal Bypass Patients.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Enhanced Recovery After Surgery; Female; Gabapentin; Humans | 2022 |
Compatibility of intravenous acetaminophen with morphine, fentanyl and ketamine in acute pediatric pain setting.
Topics: Acetaminophen; Acute Pain; Analgesics, Opioid; Child; Double-Blind Method; Fentanyl; Humans; Ketamin | 2022 |
Standing Intravenous Acetaminophen Is Associated With a Reduction of Post-operative Opioid Use in Infants Aged Less Than 1 Year Treated on the Acute Care Floor.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Opiate Alkaloids; Opioid-Related Disorders; Pain, Postope | 2022 |
The analgesic effect of the intravenous administration of acetaminophen for pediatric laparoscopic appendectomy: A comparison of scheduled and on-demand procedures.
Topics: Acetaminophen; Acute Disease; Administration, Intravenous; Appendectomy; Appendicitis; Child; Humans | 2022 |
Impact of timing of multimodal analgesia in enhanced recovery after cesarean delivery protocols on postoperative opioids: A single center before-and-after study.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Human | 2022 |
Preemptive multimodal analgesia and post-operative pain outcomes in total hip and total knee arthroplasty.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arthroplasty, Replacem | 2023 |
Acetaminophen: Is Too Much of a Good Thing Too Much?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2022 |
Opioid Consumption After Urogynecologic Surgery: A Prospective Multicenter Observational Study Using a Text-Messaging Survey Tool.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Female; Humans; Ibuprof | 2022 |
Evaluation of a Novel Multimodal Opioid-Free Postoperative Pain Management Pathway Following Robotic-Assisted Radical Prostatectomy: A Pilot Series in the Veteran Population.
Topics: Acetaminophen; Analgesics, Opioid; Gabapentin; Humans; Hydrocodone; Ketorolac; Male; Pain, Postopera | 2022 |
Sustaining standardized opioid prescribing practices after pediatric tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, P | 2022 |
Postoperative Gabapentin's Effect on Opioid Consumption and Pain Control Following Sinonasal Surgery.
Topics: Acetaminophen; Analgesics, Opioid; Female; Gabapentin; Humans; Hydrocodone; Male; Middle Aged; Pain | 2023 |
Optimal Timing of Intravenous Acetaminophen Administration for Postoperative Analgesia.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia; Analgesics; Analgesics, Non-Narcotic; | 2022 |
A Prospective Analysis of Opioid Use Following Outpatient Pediatric Urologic Surgery.
Topics: Acetaminophen; Analgesics, Opioid; Child; Child, Preschool; Female; Humans; Ibuprofen; Male; Opioid- | 2022 |
Pain management after microtia repair with costal cartilage: De-escalation and opioid use reduction.
Topics: Acetaminophen; Analgesics, Opioid; Child; Congenital Microtia; Costal Cartilage; Humans; Narcotics; | 2022 |
Use of Scheduled Nonopioid Analgesia to Decrease Inpatient Opioid Consumption After Scheduled Cesarean Birth.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Ibuprofen; I | 2022 |
Incidence of and predictors for serious opioid-related adverse drug events.
Topics: Acetaminophen; Analgesics, Opioid; Drug-Related Side Effects and Adverse Reactions; Humans; Hydrocod | 2022 |
A Case Illustrating the Practical Application of the AAOS Clinical Practice Guideline: Pharmacologic, Physical, and Cognitive Pain Alleviation for Musculoskeletal Extremity/Pelvis Surgery.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cognition; Cyclooxygenas | 2022 |
Opioid and non-opioid analgesic prescribing practices for pediatric adenotonsillectomy in a tertiary care center.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Humans; Pain, Postop | 2022 |
Problems in self-management of analgesics after outpatient shoulder surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opi | 2022 |
Opioid-Prescribing Patterns in Connecticut and New Jersey Following Third Molar Extractions.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Connecticut | 2022 |
Effect of Standing Intravenous Acetaminophen on Postoperative Opioid Exposure in a Pediatric Cardiac Intensive Care Unit.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Humans; Intensive Care Units, Pe | 2023 |
Remote smart pill cap monitoring of post-surgical pain management in thyroid and parathyroid surgery.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Ibuprofen; Pain, Postoperative; Pilot Projects; Prospecti | 2023 |
Does Facial Fracture Management Require Opioids? A Pilot Trial of a Narcotic-Minimizing Analgesia Protocol for Operative Facial Trauma.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Narcotics; Pain, Pos | 2023 |
Efficacy and feasibility of scheduled intravenous acetaminophen administration after pancreatoduodenectomy: a propensity score-matched study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid | 2023 |
Opioid sparing effects of intravenous and oral acetaminophen in hip fracture patients: A population-based study.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Hip Fractu | 2023 |
The Association Between Enhanced Recovery After Cardiac Surgery-Guided Analgesics and Postoperative Delirium.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Cardiac Surgical Procedures; Dexmedetomidine; | 2023 |
Liposomal Bupivacaine Decreases Intravenous Opioid Use in Patients with Hip Fracture: A Modification to a Novel Pain Protocol.
Topics: Acetaminophen; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Delirium; Hip | 2023 |
Analgesic Patterns and Opioid Administration in Children Hospitalized With Acute Pancreatitis.
Topics: Acetaminophen; Acute Disease; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroida | 2023 |
Paracetamol and ibuprofen combination for the management of acute mild-to-moderate pain in children: expert consensus using the Nominal Group Technique (NGT).
Topics: Acetaminophen; Acute Pain; Administration, Oral; Analgesics, Non-Narcotic; Child; Consensus; Drug Co | 2023 |
Multimodal evaluation of locoregional anaesthesia efficacy on postoperative pain after robotic pulmonary lobectomy for NSCLC: a pilot study.
Topics: Acetaminophen; Analgesics, Opioid; Carcinoma, Non-Small-Cell Lung; Humans; Lung Neoplasms; Morphine; | 2023 |
Pharmacokinetics and effects of codeine in combination with acetaminophen on thermal nociception in horses.
Topics: Acetaminophen; Analgesics; Animals; Codeine; Double-Blind Method; Drug Combinations; Drug Therapy, C | 2023 |
Intravenous patient-controlled analgesia regimen in postoperative pain management following elective cesarean section: A single-center retrospective evaluation.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics, Opioid; Cesarean Section; Female; Humans; | 2023 |
Providers' Perceptions Versus Practices Inform Pediatric Colorectal Enhanced Recovery After Surgery Implementation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Colorectal Neoplasms; Enhanced Recovery After Surger | 2023 |
Oral paracetamol dosing in hospitalised children in the UK.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child, Hospitalized; Double-Blind Method; Humans; Pa | 2023 |
Comparison of outcome of compression dressing for two days Vs seven days after varicose surgery.
Topics: Acetaminophen; Humans; Pain, Postoperative; Saphenous Vein; Stockings, Compression; Treatment Outcom | 2022 |
Opioid-Sparing Protocol for Endocrine Surgery (OSPREY): A Prospective Study.
Topics: Acetaminophen; Analgesics, Opioid; Humans; Ibuprofen; Pain, Postoperative; Prospective Studies | 2023 |
Does Liposomal Bupivacaine Injectable Suspension Peripheral Nerve Block Further Aid in Decreasing At-home Narcotic Utilization in Children and Adolescents After Anterior Cruciate Ligament Reconstruction.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Opioid; Anesthetics, Local; Anterior Cruciate Lig | 2023 |
Oral versus intravenous acetaminophen for perioperative pain management in adult patients undergoing non-cardiac surgery: A quantile segmented regression analysis.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Middle Aged; Narcotics; | 2023 |
A service evaluation of the impact of parental information provision on analgesia administration at home posttonsillectomy.
Topics: Acetaminophen; Analgesia; Analgesics; Child; Humans; Ibuprofen; Morphine; Pain, Postoperative; Paren | 2023 |
Efficacy and safety of patient-controlled thoracic epidural analgesia alone versus patient-controlled intravenous analgesia with acetaminophen after laparoscopic distal gastrectomy for gastric cancer: a propensity score-matched analysis.
Topics: Acetaminophen; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; G | 2023 |
Opioid-Free Discharge After Pancreatic Resection Through a Learning Health System Paradigm.
Topics: Acetaminophen; Adult; Aftercare; Aged; Analgesics, Opioid; Celecoxib; Cohort Studies; Female; Humans | 2023 |
An opioid-minimizing multimodal pain regimen reduces opioid exposure and pain in trauma-injured patients at high risk for opioid misuse: Secondary analysis from the mast trial.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Bayes Theorem; Gabapentin; Humans; Morphine Derivativ | 2023 |
Outcomes of hip fracture treatment with intravenous morphine and with other analgesics: postoperative analgesic medical expense, severity of pain and hospitalisation-a retrospective study.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2023 |
Implementation of a Multimodal Pain Management Order Set Reduces Perioperative Opioid Use after Liver Transplantation.
Topics: Acetaminophen; Adult; Analgesics; Analgesics, Opioid; Drug Therapy, Combination; Female; Gabapentin; | 2019 |
Paracetamol-Galactose Conjugate: A Novel Prodrug for an Old Analgesic Drug.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Carcinoma, Hepatocellular; Cell Proliferation; Gal | 2019 |
Optimizing Perioperative Pain Control After Ambulatory Urogynecologic Surgery.
Topics: Acetaminophen; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2020 |
Evolution of an Opioid Sparse Pain Management Program for Total Knee Arthroplasty With the Addition of Intravenous Acetaminophen.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Humans | 2020 |
Remifentanil for abdominal surgery is associated with unexpectedly unfavorable outcomes.
Topics: Acetaminophen; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2020 |
Enhanced recovery after surgery (ERAS) protocol reduces perioperative narcotic requirement and length of stay in patients undergoing mastectomy with implant-based reconstruction.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Breast Implantation; Breast Neoplasms; Dose-Response | 2020 |
Cost-effective multimodal analgesia in the perioperative period: Use of intravenous vs. oral acetaminophen.
Topics: Acetaminophen; Administration, Intravenous; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2020 |
Contemporary Approaches to Postoperative Pain Management.
Topics: Acetaminophen; Adrenergic alpha-2 Receptor Agonists; Analgesics, Opioid; Anesthesia, Conduction; Ane | 2019 |
The SiLaC procedure for pilonidal sinus disease: long-term outcomes of a single institution prospective study.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Female; Follow-Up Studies; Humans; Laser | 2019 |
How We Do It: Postoperative Pain Control in Mohs Micrographic Surgery.
Topics: Acetaminophen; Aged; Analgesics; Anesthesia, Local; Anesthetics, Local; Breakthrough Pain; Celecoxib | 2021 |
Reducing postoperative pain in children undergoing strabismus surgery: From bundle implementation to clinical decision support tools.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Antiemetics; Child | 2020 |
The effect of a scheduled regimen of acetaminophen and ibuprofen on opioid use following cesarean delivery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2020 |
The Effect of Intravenous Acetaminophen on Patient Outcomes within a Large Integrated Delivery Network.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Delivery of Health Care, Integrated; Female; Humans; Infusi | 2020 |
Oral Versus Intravenous Acetaminophen within an Enhanced Recovery after Surgery Protocol in Colorectal Surgery.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Colorect | 2020 |
Effect of Over the Counter Ibuprofen Dosing after Sinus Surgery for Chronic Rhinosinusitis: A Prospective Cohort Pilot Study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Chronic Disease; Cohort St | 2020 |
Defining Typical Acetaminophen and Narcotic Usage in the Postoperative Rhinoplasty Patient.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Male; Oxycodone; | 2021 |
Clinical evaluation of postoperative analgesia, cardiorespiratory parameters and changes in liver and renal function tests of paracetamol compared to meloxicam and carprofen in dogs undergoing ovariohysterectomy.
Topics: Acetaminophen; Analgesia; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carbazoles; Cardiorespir | 2020 |
The Effect of Sphenopalatine Ganglion Block on the Postoperative Pain in Patients Undergoing Septorhinoplasty.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Case-Control Studies; Female; Hu | 2020 |
Effects of Acetaminophen, NSAIDs, Gabapentinoids, and Their Combinations on Postoperative Pulmonary Complications After Total Hip or Knee Arthroplasty.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Hip; Arthr | 2020 |
No pain is gain: A prospective evaluation of strict non-opioid pain control after pediatric appendectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Appendectomy; Appendicitis; | 2020 |
Prospective Study of Acute Opioid Use After Adolescent Anterior Cruciate Ligament Reconstruction Shows No Effect From Patient- or Surgical-Related Factors.
Topics: Acetaminophen; Adolescent; Age Factors; Analgesics, Opioid; Anterior Cruciate Ligament; Child; Drug | 2020 |
Comparison of the short-term outcomes of using DST and PPH staplers in the treatment of grade III and IV hemorrhoids.
Topics: Acetaminophen; Anal Canal; Analgesics; Anus Diseases; Constriction, Pathologic; Equipment Design; Fe | 2020 |
Implementation of Opioid-Free Thyroid and Parathyroid Procedures: A Single Center Experience.
Topics: Academic Medical Centers; Acetaminophen; Aged; Analgesics, Opioid; Drug Combinations; Drug Prescript | 2020 |
Scheduled intravenous acetaminophen versus nonsteroidal anti-inflammatory drugs (NSAIDs) for better short-term outcomes after esophagectomy for esophageal cancer.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Aged, 80 and over; Anastomotic Leak; Anti-Inflamma | 2020 |
Comparison of types 2 and 3 quadratus lumborum muscle blocks : Open inguinal hernia surgery in patients with spinal anesthesia.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Spinal; Anesthe | 2020 |
Parental assessment of pain control following pediatric adenotonsillectomy: Do opioids make a difference?
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child | 2020 |
Perioperative Multimodal Analgesia Reduces Opioid Use Following Skin Grafting in Nonintubated Burn Patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Bandages; | 2020 |
A comprehensive model for pain management in patients undergoing pelvic reconstructive surgery: a prospective clinical practice study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2020 |
The effect of intraoperative intravenous acetaminophen on intraoperative and postoperative opioid use and pain scores in minimally invasive spine surgery.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Pa | 2020 |
Correction to Meta-analysis of Intravenous Acetaminophen (paracetamol) Versus Placebo Post-bariatric Surgery.
Topics: Acetaminophen; Bariatric Surgery; Humans; Obesity, Morbid; Pain, Postoperative; Randomized Controlle | 2020 |
The Effect of Ibuprofen Dosing Interval on Post-Tonsillectomy Outcomes in Children: A Quality Improvement Study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Drug Administration Schedule; Emergency Service, Hos | 2020 |
Post-operative discomforts in children after extraction of primary teeth.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Local; Child; Child, P | 2020 |
Intravenous Versus Oral Acetaminophen in Outpatient Cystoscopy Procedures: Retrospective Comparison of Postoperative Opioid Requirements and Analgesia Scores.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Aged; Analgesics, Non-Narcotic; An | 2020 |
Effectiveness of scheduled intravenous acetaminophen in the postoperative pain management of video-assisted thoracic surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Administration Schedule; Female; Humans; Infusions, In | 2021 |
Patient Satisfaction and Refill Rates After Decreasing Opioids Prescribed for Urogynecologic Surgery.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Clinical Protocols; Combined Modality Ther | 2020 |
Small trial did not find evidence that preemptive use of acetaminophen or ibuprofen reduces perioperative pain in children undergoing primary molar extraction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Humans; Ibuprofen; Molar; Pain, Postoperative | 2020 |
Pediatric Post-Tonsillectomy Opioid Prescribing Practices.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2021 |
Postoperative pain course after paediatric tonsillectomy: A prospective observational study comparing one behavioural and one numerical pain assessment tool.
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Humans; Pain Measurement; Pain, Postoperative; T | 2020 |
The Effect of Continuous Field Block through Intercostal Muscles after Atrial Septal Defect Closure via a Mini-Right Thoracotomy in Pediatric Patients.
Topics: Acetaminophen; Anesthesia, Local; Child; Female; Heart Defects, Congenital; Heart Septal Defects, At | 2021 |
Effect of preoperative intravenous vs oral acetaminophen on postoperative opioid consumption in an enhanced recovery after surgery (ERAS) program in patients undergoing open gynecologic oncology surgery.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Aged; Aged, 80 and over; An | 2021 |
Opioid-free multimodal analgesia pathway to decrease opioid utilization after cesarean delivery.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Female; Humans; Oxycodone; Pain, Postoperative; Pregna | 2021 |
Impact of a multimodal analgesic protocol modification on opioid consumption after cesarean delivery: a retrospective cohort study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2022 |
Effectiveness of ibuprofen plus paracetamol combination on persistence of acute musculoskeletal disorders in primary care patients.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Female; Humans; Ibuprofen; Midd | 2021 |
Parental Assessment of Pain Control Following Pediatric Circumcision: Do Opioids Make a Difference?
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Ci | 2021 |
The feasibility and safety in using acetaminophen with fentanyl for pain control after liver resection with regards to liver function: A prospective single-center pilot study in Japan.
Topics: Acetaminophen; Feasibility Studies; Fentanyl; Humans; Japan; Liver; Pain, Postoperative; Pilot Proje | 2021 |
Postoperative Pain Scores After Open Inguinal Hernia Repair: Comparison of Three Postoperative Analgesic Regimens.
Topics: Acetaminophen; Adult; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method | 2020 |
Opioid use after cesarean: a cohort study comparing combined versus separate oxycodone and acetaminophen regimens.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Female; Humans; | 2022 |
Postoperative around-the-clock administration of intravenous acetaminophen for pain control following robot-assisted radical prostatectomy.
Topics: Acetaminophen; Administration, Intravenous; Aged; Female; Humans; Male; Middle Aged; Pain, Postopera | 2021 |
Can NSAIDs and Acetaminophen Effectively Replace Opioid Treatment Options for Acute Pain?
Topics: Acetaminophen; Acute Pain; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2021 |
Average narcotic usage in a group of TKA patients following a modern TKA protocol.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Spinal; Anti-Inflammatory Ag | 2021 |
Opioid Free Ureteroscopy: What is the True Failure Rate?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Diclofenac; Drug Prescriptions; Female; | 2021 |
Effect of Intravenous Acetaminophen on Mean Arterial Blood Pressure: A Post Hoc Analysis of the EFfect of Intravenous ACetaminophen on PosToperative HypOxemia After Abdominal SurgeRy Trial.
Topics: Abdomen; Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesics, Non-Narcotic; Blood Pr | 2021 |
A retrospective analysis of the effects of different analgesics on the pain of patients with traumatic thoracolumbar fractures in the peri-treatment period.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Chronic Pain; Cod | 2021 |
Recommendations for total hip arthroplasty pain management: what's old, what's new and what continues to be missing?
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty | 2021 |
Is the Preoperative Use of Antidepressants and Benzodiazepines Associated with Opioid and Other Analgesic Use After Hip and Knee Arthroplasty?
Topics: Acetaminophen; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Antidepressive Age | 2021 |
The impact of intravenous acetaminophen pricing on opioid utilization and outcomes for children with appendicitis.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Opioid; Appendectomy; Appendicit | 2021 |
Analgesia After Cesarean Delivery in the United States 2008-2018: A Retrospective Cohort Study.
Topics: Acetaminophen; Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Non-Narcotic; Analgesics, Opio | 2021 |
Underutilization of Acetaminophen in Older Adult Trauma Patients.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans | 2022 |
Paracetamol, non-steroidal anti-inflammatory drugs and glucocorticoids for postoperative pain: A protocol for a systematic review with meta-analysis and trial sequential analysis.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Glucocorticoids; Humans; Meta-Analysis as To | 2021 |
Preemptive analgesia for endoscopic sinus surgery: a retrospective study.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Humans; Pain, Postoperative; Retrospective Studies | 2021 |
Pain in children undergoing tonsillotomy with alternating ibuprofen and paracetamol - a prospective observational study.
Topics: Acetaminophen; Child; Humans; Ibuprofen; Infant; Pain Measurement; Pain, Postoperative; Tonsillectom | 2021 |
Preemptive Acetaminophen: Quantification of Opioid-sparring Effects and Need for Further Research.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Pain, Postoperative | 2021 |
Reduction of Opioid Overprescribing and Use Following Standardized Educational Intervention: A Survey of Patient Experiences Following Anorectal Procedures.
Topics: Acetaminophen; Adult; Anal Canal; Analgesics, Non-Narcotic; Analgesics, Opioid; Colorectal Surgery; | 2021 |
A standardized post-cesarean analgesia regimen reduces postpartum opioid use.
Topics: Acetaminophen; Analgesia; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Female; Human | 2022 |
Topical Ropivacaine in Prevention of Post-Tonsillectomy Pain in Adults.
Topics: Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Amides; Analgesics, Non-Narcotic; | 2017 |
[Application of multimodal analgesia in radical gastrectomy for gastric cancer patients: a prospective nonrandomized controlled study].
Topics: Acetaminophen; Amides; Analgesia, Patient-Controlled; China; Comparative Effectiveness Research; Def | 2017 |
Intravenous Acetaminophen.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroid | 2017 |
Anaesthetic management of a patient with Michels syndrome.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, General; Anesthetics; Child, Preschool; Cranios | 2017 |
Patients at Risk: Large Opioid Prescriptions After Total Knee Arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Knee; Drug Co | 2017 |
Preemptive analgesia by using celecoxib combined with tramadol/APAP alleviates post-operative pain of patients undergoing total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacem | 2017 |
Rethinking Pain Management in Endoscopic Sinus Surgery.
Topics: Acetaminophen; Analgesics; Endoscopy; Humans; Pain Management; Pain, Postoperative; Paranasal Sinuse | 2017 |
Comparative Analysis of Inpatient Costs for Obstetrics and Gynecology Surgery Patients Treated With IV Acetaminophen and IV Opioids Versus IV Opioid-only Analgesia for Postoperative Pain.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cos | 2017 |
Oral Multimodal Analgesia for Total Joint Arthroplasty.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Re | 2017 |
Evaluation of Pain Assessment Techniques and Analgesia Efficacy in a Female Guinea Pig (
Topics: Acetaminophen; Analgesics, Opioid; Animals; Buprenorphine; Carbazoles; Drug Therapy, Combination; Fe | 2017 |
Variability in opioid prescribing for children undergoing ambulatory surgery in the United States.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflammatory Age | 2017 |
Variability in opioid prescribing for children undergoing ambulatory surgery in the United States.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflammatory Age | 2017 |
Variability in opioid prescribing for children undergoing ambulatory surgery in the United States.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflammatory Age | 2017 |
Variability in opioid prescribing for children undergoing ambulatory surgery in the United States.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflammatory Age | 2017 |
Multimodal oral analgesic protocol after cuff rotator arthroscopic surgery: A retrospective comparative study.
Topics: Acetaminophen; Arthroscopy; Clinical Protocols; Humans; Ketoprofen; Morphine; Pain, Postoperative; R | 2017 |
Gender and arch effects on the use of non-opioid analgesics for post endodontic pain reduction.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Therapy, Combination; Female; Humans; Ibuprofen; Male; | 2018 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Multimodal Analgesia in Outpatient Head and Neck Surgery: A Feasibility and Safety Study.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anti | 2017 |
Pain after tonsillectomy: effectiveness of current guidelines?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Drug Therapy, | 2018 |
Acetaminophen plus caffeine or plus codeine probably results in less pain but more swelling in patients undergoing placement of a single implant without bone grafting in the posterior zone.
Topics: Acetaminophen; Bone Transplantation; Caffeine; Codeine; Humans; Pain, Postoperative | 2018 |
Analgesic Consumption Following Outpatient Carpal Tunnel Release.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2018 |
Efficacy of Intravenous Acetaminophen for Postoperative Analgesia in Primary Total Knee Arthroplasty.
Topics: Acetaminophen; Administration, Intravenous; Aged; Aged, 80 and over; Analgesia; Analgesics, Opioid; | 2018 |
Hospitalization costs and resource allocation in cholecystectomy with use of intravenous versus oral acetaminophen.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Cholecys | 2018 |
Neutrophil lymphocyte ratio predicts postoperative pain after orthognathic surgery.
Topics: Acetaminophen; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Fem | 2017 |
Intravenous Acetaminophen Reduces Length of Stay Via Mediation of Postoperative Opioid Consumption After Posterior Spinal Fusion in a Pediatric Cohort.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adolescent; Analgesics; Analgesics | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
Reduction in Opioid Prescribing Through Evidence-Based Prescribing Guidelines.
Topics: Acetaminophen; Aged; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Drug Prescriptions; Evidence | 2018 |
A new postoperative pain management (intravenous acetaminophen: Acelio®) leads to enhanced recovery after esophagectomy: a propensity score-matched analysis.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, Epidural; Drug Admini | 2018 |
Combined Popliteal Catheter With Single-Injection vs Continuous-Infusion Saphenous Nerve Block for Foot and Ankle Surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Ankle Injuries; Bupivacaine; Catheters, Indwelling; | 2018 |
Outcomes During a Transition Period from Open to Laparoscopic Pyloromyotomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Incisional Hernia; Infant; Laparoscopy; Lea | 2018 |
Perioperative Celecoxib and Postoperative Opioid Use in Hand Surgery: A Prospective Cohort Study.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Multimodal analgesia decreases opioid consumption after shoulder arthroplasty: a prospective cohort study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2018 |
Cost-effectiveness of intravenous acetaminophen and ketorolac in adolescents undergoing idiopathic scoliosis surgery.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2018 |
Diclofenac--Acetaminophen Combination Induced Acute Kidney Injury In Postoperative Pain Relief.
Topics: Acetaminophen; Acute Kidney Injury; Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Presch | 2018 |
Bridging multimodal pain management provides 48-hour pain control in patients undergoing total shoulder replacement.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthe | 2018 |
Preoperative pain measures ineffective in outpatient abdominal surgeries.
Topics: Abdomen; Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Anti-Inflammatory Agents, Non-St | 2018 |
Controlling postoperative use of i.v. acetaminophen at an academic medical center.
Topics: Academic Medical Centers; Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Anal | 2018 |
Impact of Intravenous Acetaminophen on Lengths of Stay and Discharge Status after Total Knee Arthroplasty.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Knee | 2019 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
The effect of postoperative steroids on post-tonsillectomy pain and need for postoperative physician contact.
Topics: Acetaminophen; Anti-Inflammatory Agents; Child; Child, Preschool; Dexamethasone; Emergency Service, | 2018 |
Opioid Sparing in Cleft Palate Surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cleft Palate; Female; Humans; Infant; L | 2018 |
Intravenous Acetaminophen Does Not Reduce Inpatient Opioid Prescription or Opioid-Related Adverse Events Among Patients Undergoing Spine Surgery.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cost | 2018 |
Comparison of tramadol/acetaminophen fixed-dose combination, tramadol, and acetaminophen in patients undergoing ambulatory arthroscopic meniscectomy.
Topics: Acetaminophen; Adult; Analgesics; Arthroscopy; Dose-Response Relationship, Drug; Drug Combinations; | 2018 |
Transition to Nonopioid Analgesia Does Not Impair Pain Control After Major Aesthetic Plastic Surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anticonvulsants; Celecoxib; Cyclooxygenase 2 Inhibit | 2018 |
Impact of Intravenous Acetaminophen on Perioperative Opioid Utilization and Outcomes in Open Colectomies: A Claims Database Analysis.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Coho | 2018 |
Effective Postoperative Analgesia Using Intravenous Flurbiprofen and Acetaminophen.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Ant | 2018 |
Nonnarcotic analgesics reduce average pain up to 24 hours after endodontic treatment compared with placebo.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain, Post | 2018 |
Safety in Acute Pain Medicine-Pharmacologic Considerations and the Impact of Systems-Based Gaps.
Topics: Acetaminophen; Acute Pain; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Humans; K | 2018 |
Continuous local bupivacaine wound infusion with neuraxial morphine reduces opioid consumption after cesarean delivery.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, S | 2019 |
Postoperative Pain and Opioid Analgesic Requirements After Orthognathic Surgery.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; F | 2018 |
Administration of Oral Acetaminophen to Reduce Costs for the Hysterectomy Patient at a Community Hospital.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Adult; Aged; Analgesics, Non-Narco | 2019 |
Implementing a standardised discharge analgesia guideline to reduce paediatric post tonsillectomy pain.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesics; Child; Child, Preschool; Clinical Protocols; Drug | 2018 |
Clinically effective implementation of intravenous paracetamol as primary analgesia after major surgery in neonates and young infants.
Topics: Acetaminophen; Administration, Intravenous; Analgesia; Analgesics, Non-Narcotic; Female; Humans; Inf | 2018 |
Development of Multimodal Analgesia Pathways in Outpatient Thyroid and Parathyroid Surgery and Association With Postoperative Opioid Prescription Patterns.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anti-Inflammatory Age | 2018 |
Possible confounders in study of oral versus i.v. acetaminophen for postoperative pain control.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Humans; Pain, Postoperative | 2018 |
Opioid Prescription Patterns After Rhinoplasty.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Female; Humans; Male; Massachusetts; Pain, Postoperative; | 2019 |
Reduced length of stay and hospitalization costs among inpatient hysterectomy patients with postoperative pain management including IV versus oral acetaminophen.
Topics: Acetaminophen; Administration, Intravenous; Administration, Oral; Analgesics, Non-Narcotic; Database | 2018 |
Why Do We Prescribe Vicodin?.
Topics: Acetaminophen; Analgesics, Opioid; Drug Combinations; Drug Prescriptions; Humans; Hydrocodone; Molar | 2017 |
Prospective Evaluation of Opioid Consumption Following Cubital Tunnel Decompression Surgery.
Topics: Acetaminophen; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Cubital Tunnel Syndr | 2019 |
Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery.
Topics: Acetaminophen; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anti-Anxiety Agen | 2019 |
Liposomal bupivacaine reduces narcotic use and time to flatus in a retrospective cohort of patients who underwent laparotomy.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Bupivacaine; Combined Modality Th | 2018 |
Multimodal Postoperative Pain Control Is Effective and Reduces Opioid Use After Laparoscopic Roux-en-Y Gastric Bypass.
Topics: Acetaminophen; Administration, Oral; Adult; Aged; Analgesics, Opioid; Breakthrough Pain; Celecoxib; | 2019 |
"Randomization at the Expense of Relevance." L. J. Cronbach and Intravenous Acetaminophen as an Opioid-Sparing Adjuvant.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Inpatients; Pain, Postoperative; Random Allocation | 2018 |
Perioperative pain and post-operative nausea and vomiting (PONV) management after day-case surgery: The SFAR-OPERA national study.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; | 2019 |
Postoperative pain after vitreo-retinal surgery is influenced by surgery duration and anesthesia conduction.
Topics: Acetaminophen; Age Factors; Aged; Analgesics; Anesthesia, Conduction; Anesthesia, General; Anesthesi | 2019 |
Prevention and Management of Post-Operative Pain in Oral Surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Oral Surgical Procedures; Pain, | 2018 |
Utilization of a novel interactive mobile health platform to evaluate functional outcomes and pain following septoplasty and functional endoscopic sinus surgery.
Topics: Acetaminophen; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations | 2019 |
Scheduled Intravenous Acetaminophen for Postoperative Management of Patients Who Had Thoracoscopic Esophagectomy for Esophageal Cancer.
Topics: Acetaminophen; Administration, Intravenous; Aged; Esophageal Neoplasms; Esophagectomy; Female; Human | 2019 |
Acetaminophen dosing in the era of enhanced recovery after surgery.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Humans; Obesity; Pain, Postoperative; Young Adu | 2019 |
The glycation products before and after therapy for acute and chronic pain.
Topics: Acetaminophen; Acute Pain; Adult; Analgesics, Opioid; Biomarkers; Chronic Pain; Female; Glycation En | 2018 |
Population Pharmacokinetic Modeling of Acetaminophen and Metabolites in Children After Cardiac Surgery With Cardiopulmonary Bypass.
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Biological Variation, Populati | 2019 |
The Utility of Oral Nonsteroidal Anti-inflammatory Drugs Compared With Standard Opioids Following Arthroscopic Meniscectomy: A Prospective Observational Study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy | 2019 |
Reduction of Postoperative Pain by Addition of Intravenous Acetaminophen after Total Hip Arthroplasty: A Retrospective Cohort Study.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Hip; Cohort Studies; Femal | 2019 |
Sage wisdom or anecdotal dictum? Equivalent opioid use after open, laparoscopic, and robotic inguinal hernia repair.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2019 |
Effectiveness of intravenous acetaminophen for postoperative pain management in hip and knee arthroplasties: a population-based study.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Non-Narcotic; Arthroplasty, Replacemen | 2019 |
Are peripheral nerve blocks effective in pain control of pediatric orthopedic tumor surgery?
Topics: Acetaminophen; Adolescent; Analgesics; Anesthetics, Local; Bone Neoplasms; Bupivacaine; Child; Child | 2019 |
Postsurgery analgesic and sedative drug use in a French neonatal intensive care unit: A single-center retrospective cohort study.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Cohort Studies; Drug Utilization; Femal | 2019 |
[Postoperative Analgesia with Regular Acetaminophen Drip Infusion after Surgery for Lung Cancer].
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Humans; Infusions, Intravenous; Lung Neoplasms; | 2019 |
Reductions in length of stay, narcotics use, and pain following implementation of an enhanced recovery after surgery program for 1- to 3-level lumbar fusion surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; | 2019 |
Children and their parents' assessment of postoperative surgical pain: Agree or disagree?
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics; Child; Child, Preschool; Female; Humans; Longi | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
Patient Satisfaction and Pain Control Using an Opioid-Sparing Postoperative Pathway.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2019 |
IV Acetaminophen-As Benign As We Thought?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Humans; Pain, Postoperative | 2019 |
Utilization of prescription opioid analgesia after oculoplastic surgery.
Topics: Acetaminophen; Analgesics, Opioid; Drug Combinations; Humans; Hydrocodone; Ophthalmologic Surgical P | 2020 |
The effect of post-operative NSAID administration on bone healing after elective foot and ankle surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Ankle Joint; Anti-Inflammatory Agents, Non-Steroidal; | 2020 |
Parents' attitudes toward post-operative narcotic use in pediatric patients.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Caregivers; Child; Child, Preschool; Female; He | 2019 |
Feasibility of erector spinae plane catheter and patient controlled analgesia for continuous perioperative analgesia in open biliary surgery: Report of two cases.
Topics: Acetaminophen; Administration, Intravenous; Analgesia, Patient-Controlled; Bupivacaine; Catheters; C | 2020 |
How low can you go: Achieving postoperative outpatient pain control without opioids.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Appendectomy; Cholecystectomy, Laparosc | 2019 |
Post-Tonsillectomy Outcomes in Children With and Without Narcotics Prescriptions.
Topics: Acetaminophen; Adolescent; Analgesics; Child; Child, Preschool; Codeine; Databases, Factual; Drug Co | 2021 |
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female | 2021 |
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female | 2021 |
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female | 2021 |
Narcotic Free Cervical Endocrine Surgery: A Shift in Paradigm.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Opioid; Endocrine System Diseases; Female | 2021 |
Application of current pain management concepts to the prevention and management of postoperative pain.
Topics: Acetaminophen; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Cycl | 2013 |
Suboptimal pain treatment after craniotomy.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Craniotomy; Female; Humans | 2013 |
A prospective study of parents' compliance with their child's prescribed analgesia following tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Humans; Male; | 2013 |
Scheduled analgesic regimen improves rehabilitation after hip fracture surgery.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; Biomechanical | 2013 |
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2013 |
The comparison of two analgesic regimes after ambulatory surgery: an observational study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesia; Analgesics; Diclo | 2014 |
Wither codeine?
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; | 2013 |
[Assessment of practices in postoperative analgesia in caesarean before and after implementation of an information program].
Topics: Acetaminophen; Adult; Analgesia, Obstetrical; Analgesics; Anesthesia, General; Anesthesia, Obstetric | 2013 |
Multimodal analgesia therapy reduces length of hospitalization in patients undergoing fusions of the ankle and hindfoot.
Topics: Acetaminophen; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthesia, General; A | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Continuous postoperative analgesia via quadratus lumborum block - an alternative to transversus abdominis plane block.
Topics: Abdominal Muscles; Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesi | 2013 |
Codeine and acetaminophen recommendations for children.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Chemical and Drug Induce | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
A retrospective study of multimodal analgesic treatment after laparoscopic appendectomy in children.
Topics: Acetaminophen; Adolescent; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opio | 2013 |
The application of clinical audit to improve pain control following third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 2013 |
[Inadvertent epidural infusion of paracetamol].
Topics: Acetaminophen; Analgesia, Epidural; Bupivacaine; Epidural Space; Female; Humans; Hysterectomy; Infus | 2014 |
Survey of analgesia for cleft lip and palate repair in the UK and Republic of Ireland.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Cleft Lip; Cleft Pala | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Pain and analgesic use after robot-assisted radical prostatectomy.
Topics: Abdominal Pain; Acetaminophen; Aged; Analgesics, Opioid; Catheterization; Codeine; Drug Combinations | 2014 |
Opioids in the treatment of postoperative pain: old drugs with new options?
Topics: Acetaminophen; Analgesics, Opioid; Drug Combinations; Drug Therapy, Combination; Fentanyl; Humans; M | 2014 |
Analgesics in postoperative care in hip fracture patients with dementia - reported by nurses.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Attitude of Health Pe | 2014 |
Doing without codeine: why and what are the alternatives?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Codeine; Contraindications; Huma | 2014 |
Characterization and treatment of postsurgical dental implant pain employing intranasal ketorolac.
Topics: Acetaminophen; Administration, Intranasal; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Nar | 2013 |
Characterization and treatment of postsurgical dental implant pain employing intranasal ketorolac.
Topics: Acetaminophen; Administration, Intranasal; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Nar | 2013 |
Characterization and treatment of postsurgical dental implant pain employing intranasal ketorolac.
Topics: Acetaminophen; Administration, Intranasal; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Nar | 2013 |
Characterization and treatment of postsurgical dental implant pain employing intranasal ketorolac.
Topics: Acetaminophen; Administration, Intranasal; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Nar | 2013 |
Cost-effectiveness of intravenous acetaminophen for pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Cost-Benefit Analysis; Decision | 2014 |
Evaluation of medicated gel as a supplement to providing acetaminophen in the drinking water of C57BL/6 mice after surgery.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Drinking; Gels; Male; Mice; | 2014 |
Postoperative pain during the first week after adenoidectomy and guillotine adenotonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, | 2014 |
Outpatient analgesia via paravertebral peripheral nerve block catheter and On-Q pump--a case series.
Topics: Acetaminophen; Adolescent; Amides; Analgesia; Analgesia, Epidural; Analgesics, Non-Narcotic; Analges | 2014 |
A prescription for pain relief.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Drug Overdose; Female; Hu | 2014 |
Opioid prescribing patterns after Mohs micrographic surgery and standard excision: a survey of American Society for Dermatologic Surgery members and a chart review at a single institution.
Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Analgesics, Opioid; Carcinoma, Basal Cell; Carc | 2014 |
Efficacy and safety of transdermal fentanyl in the control of postoperative pain after photorefractive keratectomy.
Topics: Acetaminophen; Administration, Cutaneous; Adult; Analgesics, Opioid; Drug Combinations; Female; Fent | 2014 |
Transnasal endoscopic approach to the impacted maxillary canine.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Cuspid; Endoscopy; | 2014 |
Acetaminophen plus ibuprofen versus opioids for treatment of post-tonsillectomy pain in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Dehydration; D | 2014 |
Acetaminophen plus a nonsteroidal anti-inflammatory drug decreases acute postoperative pain more than either drug alone.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Humans; Pain, Post | 2014 |
Ibuprofen with acetaminophen for postoperative pain control following tonsillectomy does not increase emergency department utilization.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Age Factors; Analgesics; Child; Child, Preschool; Codeine; | 2014 |
Postoperative analgesia in patients older than 75 years undergoing intervention for per-trochanteric hip fracture: a single centre retrospective cohort study.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Cohort Studies; Drug Administration Routes; Drug Adminis | 2015 |
The addition of tramadol to a standard i.v. acetaminophen/morphine analgesia protocol in neonates: purposeful or just polypharmacy?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Male; Morphine; Pain, P | 2014 |
Covariates of intravenous paracetamol pharmacokinetics in adults.
Topics: Acetaminophen; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Computer Simul | 2014 |
Less is more: limiting narcotic prescription quantities for common orthopedic procedures.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Opioid; Arthroscopy; Drug Combinations; Female; | 2014 |
Maternal satisfaction with analgesia following hospital discharge after caesarean section.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, No | 2015 |
Multimodal pain control is associated with reduced hospital stay following open abdominal hysterectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Bupivacaine; Cohort S | 2014 |
Optimizing multimodal analgesia with intravenous acetaminophen and opioids in postoperative bariatric patients.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesia; Analgesics, Non-Narcotic; Analgesics, | 2014 |
Impact of intravenous acetaminophen on reducing opioid use after hysterectomy.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioi | 2014 |
Postmarketing review of intravenous acetaminophen dosing based on Food and Drug Administration prescribing guidelines.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Body Weight; Drug Presc | 2014 |
Ibuprofen is superior to paracetamol for pain relief following third molar removal.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Ibuprofen; Molar, Third; Pain, Postoperative; Tooth | 2014 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Methylprednisolone reduces pain and decreases knee swelling in the first 24 h after fast-track unicompartmental knee arthroplasty.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amines; Analgesics; Anti-Inflammatory Agents; Arthroplasty, | 2017 |
Development and characterization of a novel, anatomically relevant rat model of acute postoperative pain.
Topics: Acetaminophen; Acute Pain; Analgesics; Animals; Behavior, Animal; Carbazoles; Disease Models, Animal | 2015 |
Impact of Postoperative Intravenous Acetaminophen on Opioid Requirements and Pain Scores Following Gynecologic Procedures.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cas | 2016 |
Intravenous acetaminophen in bariatric surgery: effects on opioid requirements.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Bariatric Surg | 2015 |
[Postoperative non-opioid analgesics management].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Therapy, Combination; Humans; Pain Management; Pain, P | 2015 |
Ibuprofen and acetaminophen for posttonsillectomy pain.
Topics: Acetaminophen; Codeine; Emergency Service, Hospital; Female; Humans; Ibuprofen; Male; Pain, Postoper | 2015 |
Ibuprofen with acetaminophen for tonsillectomy pain.
Topics: Acetaminophen; Codeine; Emergency Service, Hospital; Female; Humans; Ibuprofen; Male; Pain, Postoper | 2015 |
Successful Rehabilitation of a Young Adult With Total Hip Arthroplasty a Decade After a Girdlestone Procedure: A Case Presentation.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Hip; Female; Femur Head Necrosis | 2015 |
Outcomes of an Alternating Ibuprofen and Acetaminophen Regimen for Pain Relief After Tonsillectomy in Children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Scheduled acetaminophen with as-needed opioids compared to as-needed acetaminophen plus opioids for post-cesarean pain management.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cesarean Section; Female; Humans | 2015 |
Severity and duration of pain after colonoscopy and gastroscopy: a cohort study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Australia; Carbon Dioxide; Co | 2015 |
Postoperative pain control after tonsillectomy.
Topics: Acetaminophen; Codeine; Dexamethasone; Emergency Service, Hospital; Female; Humans; Ibuprofen; Male; | 2015 |
A survey of the administration of prednisolone versus ibuprofen analgesic protocols after ambulatory tonsillectomy.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-In | 2015 |
[Primary surgery for cleft palate and short hospital stay (48 h): Are they compatible?].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Cleft Palate; Female; Humans; Infant; Length of Stay; Male; | 2016 |
The Potential Role of an Extended-Release, Abuse-Deterrent Oxycodone/Acetaminophen Fixed-Dose Combination Product for the Treatment of Acute Pain.
Topics: Acetaminophen; Acute Pain; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Chemistry, Phar | 2015 |
Registered Nurses' Knowledge about Adverse Effects of Analgesics when Treating Postoperative Pain in Patients with Dementia.
Topics: Acetaminophen; Adult; Age Factors; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Ste | 2015 |
A Comparative Investigation of the Analgesic Effects of Metamizole and Paracetamol in Rats.
Topics: Acetaminophen; Animals; Anti-Inflammatory Agents, Non-Steroidal; Carrageenan; Cyclooxygenase 2; Dipy | 2015 |
[Effectiveness of Sacral Intervertebral Epidural Block for Umbilical Hernia Repair in Children].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Epidural; Child, Preschool; Heart Rate; Hernia, | 2015 |
Postoperative nonsteroidal anti-inflammatory drugs and risk of bleeding in pediatric intracapsular tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Chi | 2015 |
Validity of creatine kinase as an indicator of muscle injury in spine surgery and its relation with postoperative pain.
Topics: Acetaminophen; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics; Creatine Kinase; Dipyrone; F | 2014 |
Local anesthetic wound infusion versus standard analgesia in paediatric post-operative pain control.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local | 2015 |
Closing the Gaps in Postsurgical Pain Management.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Arthroplasty, Replacement; Bupivacaine; Cyclooxygenas | 2015 |
Letter to the Editor.
Topics: Acetaminophen; Adenoidectomy; Female; Humans; Ibuprofen; Male; Pain, Postoperative; Postoperative He | 2016 |
Effect of i.v. acetaminophen on total hip or knee replacement surgery: a case-matched evaluation of a national patient database.
Topics: Acetaminophen; Administration, Intravenous; Adult; Analgesics, Non-Narcotic; Arthroplasty, Replaceme | 2015 |
Oral morphine for pain management in paediatric patients after tonsillectomy and adenotonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Administration, Oral; Adolescent; Analgesics, Non-Narcotic; Analgesics | 2015 |
Effect size comparison of ketorolac nasal spray and commonly prescribed oral combination opioids for pain relief after third molar extraction surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents | 2016 |
Response to Letter to the Editor by Bakshi et al.
Topics: Acetaminophen; Adenoidectomy; Animals; Bone and Bones; Chickens; Female; Fishes; Foreign Bodies; Hum | 2016 |
Utilization of a Preemptive, Multimodal Analgesic Regimen in Adult Ambulatory Septoplasty Patients: A Quality Improvement Project.
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Amines; Analgesics; Celecoxib; Cyclohexanecarb | 2015 |
Antinociceptive effects of vitexin in a mouse model of postoperative pain.
Topics: Acetaminophen; Analgesics; Animals; Apigenin; Disease Models, Animal; Dose-Response Relationship, Dr | 2016 |
A Comparison of Nonopioid and Opioid Oral Analgesia Following Pediatric Palatoplasty.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Combinations | 2017 |
In newborns, oral or rectal paracetamol fails to reduce procedural pain, whereas intravenous paracetamol reduces morphine requirements after major surgery.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Infant, Newborn; Morphine; Pain | 2016 |
Antinociceptive effects of sinomenine in a rat model of postoperative pain.
Topics: Acetaminophen; Analgesics; Animals; Dose-Response Relationship, Drug; Female; Male; Morphinans; Pain | 2016 |
Opioids Prescribed After Low-Risk Surgical Procedures in the United States, 2004-2012.
Topics: Acetaminophen; Adult; Age Factors; Analgesics, Opioid; Arthroscopy; Carpal Tunnel Syndrome; Cholecys | 2016 |
Postoperative Treatment of Pain after Hip Fracture in Elderly Patients with Dementia.
Topics: Acetaminophen; Administration, Oral; Aged; Aged, 80 and over; Analgesics; Analgesics, Opioid; Dement | 2016 |
Analgesic management after thoracotomy for decortication in children: a retrospective audit of 83 children managed with a paravertebral infusion-based regime.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, Opi | 2016 |
Opioid consumption in total knee arthroplasty patients: a retrospective comparison of adductor canal and femoral nerve continuous infusions in the presence of a sciatic nerve catheter.
Topics: Acetaminophen; Administration, Oral; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics | 2016 |
Is i.v. acetaminophen really superior?
Topics: Acetaminophen; Administration, Intravenous; Analgesics, Non-Narcotic; Humans; Pain, Postoperative | 2016 |
Comparative Analysis of Length of Stay and Inpatient Costs for Orthopedic Surgery Patients Treated with IV Acetaminophen and IV Opioids vs. IV Opioids Alone for Post-Operative Pain.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Cost | 2016 |
Analgesic requirements and pain experience after caesarean section under neuraxial anesthesia in women with preeclampsia.
Topics: Acetaminophen; Adult; Analgesics; Cesarean Section; Female; Humans; Isoxazoles; Oxycodone; Pain Meas | 2016 |
Pain after Major Craniotomy in a University Hospital: A Prospective Cohort Study.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Cohort Studies; Craniotomy; Female; Humans; Male; Mi | 2016 |
Intravenous Acetaminophen for Postoperative Pain Management in Patients Undergoing Living Laparoscopic Living-Donor Nephrectomy.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesics, Non-Narcotic; Analgesics, Opioi | 2017 |
Comment.
Topics: Acetaminophen; Humans; Laparoscopy; Living Donors; Nephrectomy; Pain, Postoperative | 2017 |
Single dose oral analgesics for postoperative pain have few adverse events.
Topics: Acetaminophen; Acute Pain; Administration, Oral; Analgesics; Humans; Pain, Postoperative | 2016 |
Estimating the Effect of Intravenous Acetaminophen for Postoperative Pain Management on Length of Stay and Inpatient Hospital Costs.
Topics: Acetaminophen; Administration, Intravenous; Adult; Cost Savings; Health Care Costs; Hospital Costs; | 2017 |
Chronic Use of Opioids Before and After Total Knee Arthroplasty: A Retrospective Cohort Study.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Arthralgia; Arthroplasty, Replacement, K | 2017 |
Minimizing pain medication use and its associated costs following robotic surgery.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Anti-Inflammatory Agents, Non-Steroi | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Local injection of liposomal bupivacaine combined with intravenous dexamethasone reduces postoperative pain and hospital stay after shoulder arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Anesthetics, Local; Anti-Inflamma | 2017 |
Analgesia following adenotonsillar surgery in children: is Oramorph required in addition to paracetamol and ibuprofen?
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child | 2017 |
Hospitalization Costs for Patients Undergoing Orthopedic Surgery Treated With Intravenous Acetaminophen (IV-APAP) Plus Other IV Analgesics or IV Opioid Monotherapy for Postoperative Pain.
Topics: Acetaminophen; Administration, Intravenous; Aged; Analgesics; Analgesics, Opioid; Female; Hospitaliz | 2017 |
The first 6 weeks of recovery after primary total hip arthroplasty with fast track.
Topics: Acetaminophen; Activities of Daily Living; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Proce | 2017 |
Voluntary intake of paracetamol-enriched drinking water and its influence on the success of embryo transfer in mice.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Animals; Drinking Water; Embryo Trans | 2017 |
A Non-Narcotic Pathway for the Management of Postoperative Pain Following Pediatric Robotic Pyeloplasty.
Topics: Acetaminophen; Administration, Intravenous; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory | 2017 |
Role of diclofenac sodium and paracetamol on colonic anastomosis: An experimental rodent model.
Topics: Acetaminophen; Anastomosis, Surgical; Anastomotic Leak; Animals; Anti-Inflammatory Agents, Non-Stero | 2018 |
Comparative analysis of length of stay, hospitalization costs, opioid use, and discharge status among spine surgery patients with postoperative pain management including intravenous versus oral acetaminophen.
Topics: Acetaminophen; Administration, Intravenous; Adult; Aged; Analgesics, Opioid; Female; Hospital Costs; | 2017 |
[Postoperative inconveniences after breast cancer surgery].
Topics: Acetaminophen; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyc | 2008 |
Rapamycin, mycophenolate mofetil, methylprednisolone, and cytotoxic T-lymphocyte-associated antigen 4 immunoglobulin-based conditioning regimen to induce partial tolerance to hind limb allografts without cytoreductive conditioning.
Topics: Abatacept; Acetaminophen; Analgesia; Analgesics; Animals; Buprenorphine; Hindlimb; Immune Tolerance; | 2008 |
Indirect inguinal hernia in Nigerian older children and young adults: is herniorrhaphy necessary?
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Child; Elective Surgical Procedures; Eme | 2008 |
I.V. acetaminophen pharmacokinetics in neonates after multiple doses.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Body Weight; Female; Gestational Age; Humans; Hyperbilirubi | 2008 |
Pain management for dentists.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2008 |
[Do women with Caesarean section have to choose between pain relief and breastfeeding?].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2008 |
Morphine infusions after pediatric cranial surgery: a retrospective analysis of safety and efficacy.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; British Columbia; Child; Child, Preschool; Codeine; C | 2008 |
Post-operative pain: the impact of prescribing patterns on nurses' administration of analgesia.
Topics: Acetaminophen; Analgesia; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Child; Codeine; Diclo | 2008 |
Intra-articular bupivacaine as treatment for postoperative pain after arthroscopy of the wrist.
Topics: Acetaminophen; Adolescent; Adult; Aged; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; | 2008 |
Efficacy and tolerability of ready-to-use intravenous paracetamol solution as monotherapy or as an adjunct analgesic therapy for postoperative pain in patients undergoing elective ambulatory surgery: open, prospective study.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesic | 2009 |
The evolution of analgesia in an 'accelerated' recovery programme for resectional laparoscopic colorectal surgery with anastomosis.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Anastomosis, Surgical; Colectomy; Early Ambulation; Huma | 2010 |
The evolution of analgesia in an 'accelerated' recovery programme for resectional laparoscopic colorectal surgery with anastomosis.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Anastomosis, Surgical; Colectomy; Early Ambulation; Huma | 2010 |
The evolution of analgesia in an 'accelerated' recovery programme for resectional laparoscopic colorectal surgery with anastomosis.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Anastomosis, Surgical; Colectomy; Early Ambulation; Huma | 2010 |
The evolution of analgesia in an 'accelerated' recovery programme for resectional laparoscopic colorectal surgery with anastomosis.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Anastomosis, Surgical; Colectomy; Early Ambulation; Huma | 2010 |
Current therapy: a moving target.
Topics: Acetaminophen; Alveolar Ridge Augmentation; Analgesics, Non-Narcotic; Antibiotic Prophylaxis; Bone D | 2009 |
Acute postoperative pain predicts chronic pain and long-term analgesic requirements after breast surgery for cancer.
Topics: Acetaminophen; Adult; Analgesia; Analgesics; Breast Neoplasms; Case-Control Studies; Dextropropoxyph | 2008 |
Combination of paracetamol, codeine and lidocaine for pain relief during transrectal ultrasound guided biopsy of the prostate.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthetics, Local; Biopsy, Needle; Code | 2009 |
Post-operative analgesic in children.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, N | 2008 |
Perioperative analgesia strategies in fast-track pediatric surgery of the kidney and renal pelvis: lessons learned.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Loc | 2010 |
The dextropropoxyphene controversy.
Topics: Acetaminophen; Analgesics, Opioid; Dextropropoxyphene; Humans; Licensure; Pain, Postoperative; Recep | 2009 |
Acetaminophen as a postsurgical analgesic in rats: a practical solution to neophobia.
Topics: Acetaminophen; Administration, Oral; Analgesia; Analgesics, Non-Narcotic; Animals; Behavior, Animal; | 2003 |
Etoricoxib, paracetamol, and dextropropoxyphene for postoperative pain management: a questionnaire survey of consumption of take-home medication after elective hallux valgus surgery.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Analgesics; Data Collection; Dextropropoxyphene | 2008 |
Preoperative opioid consumption increases morphine requirement after leg amputation.
Topics: Acetaminophen; Aged; Aged, 80 and over; Amides; Amputation, Surgical; Analgesics, Non-Narcotic; Anal | 2009 |
Therapeutic dose of acetaminophen may induce fulminant hepatitis in the presence of risk factors: a report of two cases.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; Humans; Liver Failure, Acute; Middle Aged; P | 2009 |
A comparison of early postoperative results between urgent closed hemorrhoidectomy for prolapsed thrombosed hemorrhoids and elective closed hemorrhoidectomy.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Elective Surgical Pro | 2009 |
Predictors of acute postoperative pain after elective surgery.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug | 2010 |
Multimodal pain management following minimally invasive total knee arthroplasty: an experience in 3-dose parecoxib.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, O | 2009 |
A prospective evaluation of 2 different pain management protocols for total hip arthroplasty.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Arthroplasty, Replacement, | 2010 |
Evidence for the use of non-steroidal anti-inflammatory drugs for acute pain in the post anaesthesia care unit.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Blood Platelets; C | 2009 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
The value of the dental impaction pain model in drug development.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Drug Design; Human | 2010 |
Comparison of perioperative oral multimodal analgesia versus IV PCA for spine surgery.
Topics: Acetaminophen; Administration, Oral; Amines; Analgesia; Analgesia, Patient-Controlled; Analgesics; A | 2010 |
Comparison of perioperative oral multimodal analgesia versus IV PCA for spine surgery.
Topics: Acetaminophen; Administration, Oral; Amines; Analgesia; Analgesia, Patient-Controlled; Analgesics; A | 2010 |
Comparison of perioperative oral multimodal analgesia versus IV PCA for spine surgery.
Topics: Acetaminophen; Administration, Oral; Amines; Analgesia; Analgesia, Patient-Controlled; Analgesics; A | 2010 |
Comparison of perioperative oral multimodal analgesia versus IV PCA for spine surgery.
Topics: Acetaminophen; Administration, Oral; Amines; Analgesia; Analgesia, Patient-Controlled; Analgesics; A | 2010 |
Prediction of postoperative pain after mandibular third molar surgery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Anxiety; Attitude; Depression; Eating; Female; Follo | 2010 |
[Pain perception and pain therapy in premature infants].
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Fentanyl; Humans; Infant; | 2010 |
[Postoperative analgesia].
Topics: Acetaminophen; Adult; Aged; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammato | 2010 |
Preemptive multimodal pain regimen reduces opioid analgesia for patients undergoing robotic-assisted laparoscopic radical prostatectomy.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; C | 2010 |
Transversus abdominis plane block for renal transplant recipients.
Topics: Abdominal Wall; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Kidney Transpla | 2010 |
The addition of metamizole to morphine and paracetamol improves early postoperative analgesia and patient satisfaction after lumbar disc surgery.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Opioid; Dose-Response Relationship, Drug; Drug The | 2010 |
Reducing postoperative pain by changing the process.
Topics: Acetaminophen; Acute Pain; Adolescent; Adult; Aged; Aged, 80 and over; Analgesics; Analgesics, Non-N | 2011 |
[Paracetamol for perioperative analgesia. Old substance - new insights].
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Chemical and Drug Induced Liver | 2010 |
A randomized clinical trial of the efficacy of scheduled dosing of acetaminophen and hydrocodone for the management of postoperative pain in children after tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Humans; Hydrocodo | 2011 |
Evaluation of pain following supratentorial craniotomy.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Craniotomy; Female; Humans; Male; Middle | 2011 |
Analgesia in fast-track paediatric cardiac patients.
Topics: Acetaminophen; Adolescent; Analgesia; Analgesia, Patient-Controlled; Analgesics, Opioid; Cardiac Sur | 2011 |
Post-craniotomy pain in a paediatric population.
Topics: Acetaminophen; Adolescent; Age Factors; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, | 2011 |
[Postoperative pain management after ambulatory surgery. A survey of anaesthesiologists].
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics; Analgesics, Opioid; Anesthesia, Conductio | 2011 |
Does use of bupivacaine-soaked pledgets aid in the care of postoperative cleft palate patients?
Topics: Acetaminophen; Administration, Topical; Anesthetics, Local; Bone Transplantation; Bupivacaine; Case- | 2011 |
[Interest of ultrasound in the realization of thoracic paravertebral block in breast surgery].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; | 2011 |
[An algorithm for postoperative pain management in visceral and thoracic surgery: an observational study].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Algorithms; Amines; Analgesia, Epidural; Analgesics; | 2013 |
Prescribing recommendations for the treatment of acute pain in dentistry.
Topics: Acetaminophen; Acute Disease; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroida | 2011 |
Determinants of patient satisfaction in postoperative pain management following hand ambulatory day-surgery.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics; Drug Administration Schedule; | 2011 |
Patient-controlled oral analgesia following cesarean section: tramadol versus a combination of tramadol and acetaminophen.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics; Cesarean Section; Drug Therapy, Com | 2011 |
Open transumbilical pyloromyotomy: is it more painful than the laparoscopic approach?
Topics: Acetaminophen; Administration, Oral; Analgesics; Anesthesia, Local; Anesthetics, Local; Anti-Inflamm | 2011 |
Treatment of pain in children after limb-sparing surgery: an institution's 26-year experience.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 2011 |
Limitations regarding double-blinding, adherence to the intention to treat principle, and postoperative dosage of paracetamol.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Carbon Dioxide; Colonic Neoplasms; Dose-Response Relationsh | 2011 |
Reply to 'Two-agent analgesia versus acetaminophen in children having bilateral myringotomies and tubes surgery'.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2011 |
Diclofenac sodium intramuscularly, or paracetamol intravenously? Question not answered.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Female | 2012 |
Oxycodone induced delirium and agitation in an elderly patient following total right knee arthroplasty.
Topics: Acetaminophen; Aged; Akathisia, Drug-Induced; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthropl | 2011 |
Single-dose intravenous paracetamol or propacetamol for prevention or treatment of postoperative pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Female; Humans; Male; Molar, Third; Pain, Postoperative; To | 2011 |
OFIRMEV: a recently introduced drug.
Topics: Acetaminophen; Acute Pain; Analgesics; Antipyretics; Clinical Trials as Topic; Drug Approval; Fever; | 2011 |
The transversus abdominis plane (TAP) block in neonates and infants - results of an audit.
Topics: Abdomen; Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anestheti | 2011 |
Multimodal analgesia including infraclavicular block in perioperative management of upper extremity amputation in neonate.
Topics: Acetaminophen; Amputation, Surgical; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesth | 2011 |
Relative efficacy of oral analgesics after third molar extraction--a 2011 update.
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Combinations; Facial Pain; | 2011 |
Transversus abdominis plane catheters for post-cesarean delivery analgesia: a series of five cases.
Topics: Abdominal Muscles; Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; | 2012 |
Aminotransferase levels in relation to short-term use of acetaminophen four grams daily in postoperative cardiothoracic patients in the intensive care unit.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Alanine Transaminase; Analgesics, Non-Nar | 2011 |
Using the Mouse Grimace Scale to reevaluate the efficacy of postoperative analgesics in laboratory mice.
Topics: Acetaminophen; Analgesics; Animals; Animals, Laboratory; Buprenorphine; Carbazoles; Dose-Response Re | 2012 |
Pharmacokinetics of a loading dose of intravenous paracetamol post caesarean delivery.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cesarean Section; Female; Humans; Infusions, Intrave | 2012 |
Safety and efficacy of intravenous acetaminophen in the elderly after major orthopedic surgery: subset data analysis from 3, randomized, placebo-controlled trials.
Topics: Acetaminophen; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Arthroplasty, Replacement; Female; | 2012 |
Comparison of the pharmacokinetics of paracetamol from two generic products in patients after total gastric resection.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Drugs, Generic; Female; Gastrectomy; Humans; Male; Mi | 2011 |
Tears at breakfast.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Child, Preschool; Drug Ther | 2012 |
Population pharmacokinetics of single-dose intravenous paracetamol in children.
Topics: Acetaminophen; Adolescent; Aging; Analgesics, Non-Narcotic; Anesthesia, General; Blood Specimen Coll | 2012 |
Anaesthetic management of a child posted for excision of lymphangioma of the tongue.
Topics: Acetaminophen; Anesthesia, General; Child; Follow-Up Studies; Humans; Intubation, Intratracheal; Lym | 2012 |
Need for improved treatment of postoperative pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Amines; Analgesics; Analgesics, Opioid; A | 2012 |
Postoperative pain assessment after functional endoscopic sinus surgery (FESS) for chronic pansinusitis.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; An | 2013 |
The effect of paracetamol, metamizole sodium and ibuprofen on postoperative hemorrhage following pediatric tonsillectomy.
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Dipyrone; Female; Humans; Ibuprofen; Male; Pain, | 2012 |
Post-operative pain and pain management in children after dental extractions under general anaesthesia.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia, General; Child; Child, Pres | 2012 |
[Continuous paravertebral analgesia versus intravenous analgesia in minimally invasive cardiac surgery by mini-thoracotomy].
Topics: Acetaminophen; Adult; Amides; Analgesia; Analgesics; Analgesics, Opioid; Anesthesia, Inhalation; Ane | 2012 |
The pharmacokinetics of a high intravenous dose of paracetamol after caesarean delivery: the effect of gestational age.
Topics: Acetaminophen; Administration, Intravenous; Adult; Cesarean Section; Comorbidity; Female; Gestationa | 2012 |
Plasma and red cell exchange transfusions for erythropoietic protoporphyria: a case report and review of the literature.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Arthroplasty, Replacement, Knee; Cholestasis, Intrahepatic; | 2012 |
Flap-off epi-LASIK versus automated epithelial brush in PRK: a prospective comparison study of pain and reepithelialization times.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Therapy, Combination; Epith | 2012 |
Additional economic and pharmacokinetic considerations of intravenous acetaminophen in acutely ill patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Costs; Humans; Pain, Postoperative | 2013 |
Authors' reply.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Drug Costs; Humans; Pain, Postoperative | 2013 |
The paracetamol concentration-effect relation in neonates.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Dose-Response Relationship, Drug; Fem | 2013 |
Nefopam after total hip arthroplasty: role in multimodal analgesia.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty | 2013 |
Pain panacea for opiophobia in infants?
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Female; Humans; Male; Morphine; Pain, P | 2013 |
Multimodal pain management after spinal surgery for adolescent idiopathic scoliosis.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Female; Humans; Infusions, Intravenous; Pain Ma | 2013 |
Effect of preoperative intravenous methocarbamol and intravenous acetaminophen on opioid use after primary total hip and knee replacement.
Topics: Acetaminophen; Aged; Analgesics, Non-Narcotic; Analgesics, Opioid; Arthroplasty, Replacement, Hip; A | 2013 |
The effect of addition of pregabalin and s-ketamine to local infiltration analgesia on the knee function outcome after total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia; Analgesics; Analgesics, Non-Narcotic; Anesthetics, Dissociative; Art | 2012 |
Observer-blinded comparison of two nonopioid analgesics for postoperative pain in piglets.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Animals; Behavior, Animal; Blood Pressure; Body Temperature | 2002 |
Effect of drainage upon access on postoperative endodontic pain and swelling in symptomatic necrotic teeth.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2002 |
[Opioids or paracetamol for postoperative analgesia in newborns and small children?].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Humans; Infant; Infant, Newborn; Pain, | 2002 |
Postoperative complaints following impacted mandibular third molar surgery in Ile-Ife, Nigeria.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Edema; Female; Humans; Ibuprofen; Male; | 2002 |
An update on analgesics for the management of acute postoperative dental pain.
Topics: Acetaminophen; Acute Disease; Adult; Aged; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, | 2002 |
Evaluation of postoperative analgesia in a rat model of incisional pain.
Topics: Acetaminophen; Analgesia; Analgesics; Animals; Biomechanical Phenomena; Buprenorphine; Clonixin; Fen | 2003 |
Ultracet: a new combination analgesic.
Topics: Acetaminophen; Analgesics; Contraindications; Drug Combinations; Facial Pain; Humans; Oral Surgical | 2003 |
Everything I know about endodontics, I learned after dental school. Part 2.
Topics: Acetaminophen; Analgesics, Opioid; Anti-Bacterial Agents; Anti-Inflammatory Agents; Anti-Inflammator | 2003 |
[Children often suffer unnecessary pain. A fever suppository after surgery is not enough!].
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Child; Dipyrone; Dose-Response Relationship, Dr | 2003 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
[Regional anesthesia for urologic interventions in the pediatric age group].
Topics: Acetaminophen; Age Factors; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia, Co | 2004 |
One shot spinal morphine injection for postthoracotomy pain control in children.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Anesth | 2004 |
Changing role of COX-2 inhibitors in the perioperative period: is parecoxib really the answer?
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Isoxazole | 2005 |
[Treatment of pain after laparoscopic cholecystectomy].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti-Inflammatory A | 2005 |
An evaluation of pain and postoperative nausea and vomiting following the introduction of guidelines for tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, General; Ant | 2005 |
Pharmaceutical prescribing for children. Part 2. Analgesia and prescribing for children in pain.
Topics: Acetaminophen; Adolescent; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammato | 2005 |
Inadvertent epidural infusion of paracetamol in a child.
Topics: Acetaminophen; Analgesia, Epidural; Analgesics, Non-Narcotic; Child; Humans; Injections, Epidural; M | 2005 |
Tramadol for acute pain: a review of the evidence.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Drug Therapy, Combination; Humans; Pain | 2005 |
Local infiltration of anaesthesia with subpectoral indwelling catheters after immediate breast reconstruction with implants: a pilot study.
Topics: Acetaminophen; Adult; Amides; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Anti | 2006 |
Review of analgesia use in the intensive care unit after heart surgery.
Topics: Acetaminophen; Analgesics; Australia; Chest Tubes; Codeine; Coronary Artery Bypass; Drug Administrat | 2006 |
Pre-emptive analgesia and protective premedication. What is the difference?
Topics: Acetaminophen; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Drug Administration Schedule; Hu | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Preoperative anxiety, postoperative pain, and behavioral recovery in young children undergoing surgery.
Topics: Acetaminophen; Adenoidectomy; Analgesics; Anxiety; Child; Child Behavior Disorders; Child, Preschool | 2006 |
Post-dural headache associated with thoracic paravertebral blocks.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-St | 2006 |
Placebo use to compare the analgesic efficacy of parenteral paracetamol and diclofenac in post-operative orthopaedic pain.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Humans | 2006 |
Intravenous paracetamol for postoperative analgesia in a 4-day-old term neonate.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anus, Imperforate; Bladder E | 2007 |
Accidental paracetamol poisoning.
Topics: Abdominal Pain; Accidents; Acetaminophen; Acute Kidney Injury; Analgesics, Non-Narcotic; Fatal Outco | 2007 |
Scheduled oral analgesics and the need for opiates in children following partial dorsal rhizotomy.
Topics: Acetaminophen; Administration, Oral; Analgesia, Epidural; Analgesics; Analgesics, Opioid; Cerebral P | 2007 |
Not all intravenous paracetamol formulations are created equal...
Topics: Acetaminophen; Analgesics, Non-Narcotic; Chemistry, Pharmaceutical; Humans; Infant, Newborn; Infusio | 2007 |
[Ambulatory pain management for children in the family practice].
Topics: Acetaminophen; Acute Disease; Ambulatory Care; Analgesics; Analgesics, Opioid; Child; Chronic Diseas | 2007 |
Which preparation of paracetamol? An audit of usage and costs.
Topics: Acetaminophen; Age Factors; Analgesics, Non-Narcotic; Child; Child, Preschool; Drug Administration R | 2007 |
Intravenous paracetamol: the 'Stockholm protocol' for postoperative analgesia of term and preterm neonates.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Anus, Imperforate; Bladder Exstrophy; Colostomy; | 2007 |
Analgesia before, during and after surgery: prevention of postoperative pain.
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
[Can the postoperative pain level be predicted preoperatively?].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Anx | 2007 |
[Case report of anesthetic management for an infant with tricho-hepato-entric syndrome].
Topics: Acetaminophen; Anesthesia, General; Child, Preschool; Diarrhea; Female; Hair; Hemochromatosis; Herni | 2007 |
Daycase laparoscopic cholecystectomy: a prospective study of post-discharge pain, analgesic and antiemetic requirements.
Topics: Acetaminophen; Aftercare; Ambulatory Surgical Procedures; Analgesics; Cholecystectomy, Laparoscopic; | 2008 |
[Acute opiate tolerance and postoperative hyperalgesia after a brief infusion of remifentanil managed with multimodal analgesia].
Topics: Acetaminophen; Adnexal Diseases; Amides; Analgesia, Epidural; Analgesics, Non-Narcotic; Analgesics, | 2008 |
The incidence of postoperative pain in children.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Child; Female; Humans; Male; Meperidine; Pain, Postop | 1983 |
[Comparative study of the analgesic activity of glafenine and a paracetamol-codeine combination in post-operative dental pain].
Topics: Acetaminophen; Adolescent; Adult; Codeine; Double-Blind Method; Drug Combinations; Evaluation Studie | 1984 |
Five studies on ibuprofen for postsurgical dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Aspirin; Codeine; Drug Combinations; Female; Humans; I | 1984 |
Salicylates and post-tonsillectomy haemorrhage.
Topics: Acetaminophen; Aspirin; Hemorrhage; Humans; Pain, Postoperative; Postoperative Complications; Prospe | 1984 |
Efficacy of paracetamol in reducing post-operative pain after periodontal surgery.
Topics: Acetaminophen; Double-Blind Method; Female; Humans; Male; Pain, Postoperative; Periodontal Diseases; | 1983 |
Drugs in dentistry: analgesics.
Topics: Acetaminophen; Analgesics; Dental Care; Drug Combinations; Humans; Pain, Postoperative | 1983 |
Is baclofen an analgesic?
Topics: Acetaminophen; Adult; Baclofen; Double-Blind Method; Humans; Male; Middle Aged; Pain, Postoperative; | 1983 |
Nalbuphine, acetaminophen, and their combination in postoperative pain.
Topics: Acetaminophen; Adult; Aged; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Mi | 1984 |
Comparison of paracetamol and pentazocine suppositories for pain relief after tonsillectomy in adults.
Topics: Acetaminophen; Adult; Anesthesia, Inhalation; Double-Blind Method; Enflurane; Female; Halothane; Hum | 1984 |
The relative efficacy of indoprofen compared with opioid-analgesic combinations.
Topics: Acetaminophen; Adult; Codeine; Dextropropoxyphene; Double-Blind Method; Drug Combinations; Drug Eval | 1981 |
Comparison of Syndol and paracetamol in the relief of dental pain.
Topics: Acetaminophen; Adolescent; Adult; Aged; Caffeine; Codeine; Double-Blind Method; Doxylamine; Drug Com | 1981 |
Comparison of diflunisal and paracetamol in the management of pain following wisdom teeth removal.
Topics: Acetaminophen; Adult; Aged; Diflunisal; Double-Blind Method; Female; Humans; Male; Middle Aged; Mola | 1982 |
Post-anaesthetic dental extraction analgesia: a comparison of paracetamol, codeine, caffeine (Solpadeine) and diflunisal (Dolobid).
Topics: Acetaminophen; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Caffeine; Codeine; | 1982 |
Postoperative analgesia for day-case herniorrhaphy patients. A comparison of cryoanalgesia, paravertebral blockade and oral analgesia.
Topics: Acetaminophen; Activities of Daily Living; Ambulatory Surgical Procedures; Analgesia; Anesthesia, Ep | 1981 |
Paracetamol, tiaramide and placebo for pain relief after orthopedic surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics; Benzothiazoles; Double-Blind Method; Female; Humans; M | 1981 |
Laparoscopic inguinal hernioplasty.
Topics: Acetaminophen; Activities of Daily Living; Elective Surgical Procedures; Follow-Up Studies; Hematoma | 1995 |
Post-tonsillectomy pain: the first ten days.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Female; Humans; Male; Pain Measurement; | 1995 |
[Optimal use of non opioid analgesics].
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, N | 1995 |
Convalescence and hospital stay after colonic surgery with balanced analgesia, early oral feeding, and enforced mobilisation.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia, Epidural; Bupivacaine; Colectomy; Convales | 1995 |
Analgesics requirement after anterior segment surgery.
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anterior Eye Segment; Cataract Extra | 1994 |
[Postoperative analgesia for ambulatory surgery in children: a comparison of 2 techniques].
Topics: Acetaminophen; Ambulatory Surgical Procedures; Anesthesia, Caudal; Child; Child, Preschool; Circumci | 1994 |
[Pain control with paracetamol following inguinal herniorrhaphy or orchidopexy in childhood].
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Child; Child, Preschool; Cryptorchidism; | 1994 |
Propofol for pulsed dye laser treatments in paediatric outpatients.
Topics: Acetaminophen; Anesthesia Recovery Period; Anesthesia, Intravenous; Child; Child, Preschool; Facial | 1994 |
Intravenous administration of paracetamol (propacetamol) for postoperative analgesia.
Topics: Acetaminophen; Analgesics; Humans; Infusions, Intravenous; Injections, Intravenous; Pain, Postoperat | 1994 |
Postoperative pain management in preverbal children: the prescription and administration of analgesics with and without caudal analgesia.
Topics: Acetaminophen; Analgesia, Epidural; Clinical Protocols; Communication Barriers; Drug Prescriptions; | 1994 |
Parental attitudes and postoperative problems related to paediatric day stay tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Ambulatory Surgical Procedures; Attitude; Child; Child, Preschool; Dri | 1994 |
Analgesia after VTOP.
Topics: Abortion, Induced; Acetaminophen; Female; Fentanyl; Humans; Pain, Postoperative; Pregnancy | 1993 |
[Paracetamol poisoning in infancy].
Topics: Acetaminophen; Dose-Response Relationship, Drug; Exchange Transfusion, Whole Blood; Female; Fetal Al | 1993 |
[Laparoscopic splenectomy. The "hanging spleen technique" in a series of nineteen cases].
Topics: Acetaminophen; Adolescent; Adult; Aged; Female; Humans; Laparoscopy; Male; Middle Aged; Morbidity; P | 1995 |
Coproxamol revisited.
Topics: Acetaminophen; Analgesics, Opioid; Dextropropoxyphene; Drug Combinations; Humans; Pain, Postoperativ | 1996 |
The treatment of pain following excimer laser photorefractive keratectomy: additive effect of local anesthetic drops, topical diclofenac, and bandage soft contact.
Topics: Acetaminophen; Adaptation, Ocular; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; | 1996 |
Complications of paediatric tonsillectomy post-discharge.
Topics: Acetaminophen; Adolescent; Child; Child Behavior; Child, Preschool; Consumer Behavior; Earache; Fema | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Parents' management of children's pain following 'minor' surgery.
Topics: Acetaminophen; Adolescent; Adult; Attitude; Caregivers; Child; Child, Preschool; Female; Humans; Mal | 1996 |
Assessment of nurses' judgement for analgesic requirements of postoperative children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Child, Preschool; Female; Humans; Male; Nursing Asse | 1996 |
Oral analgesics in the compromised dental patient: what are the options?
Topics: Acetaminophen; Administration, Oral; Analgesics; Analgesics, Opioid; Anti-Inflammatory Agents, Non-S | 1995 |
Respiratory arrest precipitated by codeine in a child with chronic renal failure.
Topics: Acetaminophen; Adenoidectomy; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Codein | 1997 |
Postoperative acute liver failure after therapeutic paracetamol administration.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Female; Humans; Liver Cirrhosis, Alcoholic; Liver Fa | 1997 |
Pain and activity disturbance after paediatric day case adenoidectomy.
Topics: Acetaminophen; Activities of Daily Living; Adenoidectomy; Ambulatory Surgical Procedures; Analgesics | 1997 |
Analgesia following thoracotomy: a survey of Australian practice.
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 1997 |
Analgesia following thoracotomy: a survey of Australian practice.
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 1997 |
Analgesia following thoracotomy: a survey of Australian practice.
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 1997 |
Analgesia following thoracotomy: a survey of Australian practice.
Topics: Acetaminophen; Analgesia; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Non-Narcot | 1997 |
Rectal paracetamol dosing regimens: determination by computer simulation.
Topics: Acetaminophen; Administration, Rectal; Adolescent; Analgesics, Non-Narcotic; Biological Availability | 1997 |
Post-tonsillectomy pain: the difference between younger and older patients.
Topics: Acetaminophen; Adolescent; Adult; Age Factors; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opi | 1997 |
Compliance in administration of prescribed analgesics.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Codeine; Drug Administration Schedule; Female; G | 1997 |
The dose-response relationship of ketorolac as a component of intravenous regional anesthesia with lidocaine.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Conduction; Anes | 1998 |
[Is it treatment with paracetamol in severe pain reasonable?].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Humans; Pain, Postoperative | 1998 |
Preemptive analgesia for postop pain.
Topics: Acetaminophen; Analgesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Drug Admi | 1998 |
Oral medication for post-Caesarean analgesia.
Topics: Acetaminophen; Administration, Oral; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory | 1998 |
Assessment of postoperative pain after laryngeal surgery for cancer.
Topics: Acetaminophen; Adult; Aged; Analgesics, Opioid; Anxiety; Blood Pressure; Carcinoma, Squamous Cell; H | 1998 |
Treatment of pain in cognitively impaired compared with cognitively intact older patients with hip-fracture.
Topics: Acetaminophen; Age Factors; Aged; Aged, 80 and over; Analgesics, Non-Narcotic; Analgesics, Opioid; C | 1998 |
-Postoperative analgesia after major surgery of the knee.
Topics: Acetaminophen; Analgesia; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics | 1998 |
A comparative study of the analgesia requirements following laparoscopic and open fundoplication in children.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Child; Child, Preschool; Fundoplication | 1998 |
Comparison of present pain intensity assessments on horizontally and vertically oriented visual analogue scales.
Topics: Acetaminophen; Adolescent; Adult; Codeine; Female; Humans; Male; Molar, Third; Oral Surgical Procedu | 1998 |
Blocks and other techniques pediatric surgeons can employ to reduce postoperative pain in pediatric patients.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; Bupivacaine; Child; | 1999 |
Paracetamol--misused good old drug?
Topics: Acetaminophen; Administration, Oral; Administration, Rectal; Analgesics, Non-Narcotic; Drug Utilizat | 1999 |
An audit of postoperative analgesia after pyloromyotomy.
Topics: Acetaminophen; Adjuvants, Anesthesia; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anes | 1999 |
[Peribulbar anesthesia for peroperative and postoperative pain control in eye enucleation or evisceration: 31 cases].
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio | 1999 |
Post tonsillectomy pain.
Topics: Acetaminophen; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, No | 1999 |
The importance of dose-response in study design.
Topics: Acetaminophen; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Humans; Ke | 1999 |
Hypnosis with conscious sedation instead of general anaesthesia? Applications in cervical endocrine surgery.
Topics: Acetaminophen; Adult; Analgesics; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Cons | 1999 |
Using the carbon dioxide laser for tonsillotomy in children.
Topics: Acetaminophen; Analgesics; Carbon Dioxide; Child; Child, Preschool; Female; Follow-Up Studies; Human | 1999 |
Tears at bedtime.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Child; Drug Administration | 1999 |
Tears at bedtime.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Child; Drug Administration | 1999 |
Postoperative analgesia after total hip arthroplasty: i.v. PCA with morphine, patient-controlled epidural analgesia, or continuous "3-in-1" block?: a prospective evaluation by our acute pain service in more than 1,300 patients.
Topics: Acetaminophen; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics; Analgesics, Non | 1999 |
Effectiveness of an acute pain service inception in a general hospital.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesiology; Anti-Inflam | 1999 |
Reporting of adverse effects in clinical trials should be improved: lessons from acute postoperative pain.
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Double-Blind Method; Humans; Ibuprofen; Pain | 1999 |
High-dose rectal and oral acetaminophen in postoperative patients--serum and saliva concentrations.
Topics: Absorption; Acetaminophen; Administration, Oral; Adolescent; Adult; Analgesics, Non-Narcotic; Female | 2000 |
The effect of a single intravenous dose of metamizol 2 g, ketorolac 30 mg and propacetamol 1 g on haemodynamic parameters and postoperative pain after heart surgery.
Topics: Acetaminophen; Aged; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Blood Pressure; Cardiac Ou | 2000 |
Using an antedependence test to analyse post-operative pain measurements.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analysis of Variance; Area Under Curve; Chi-Square Distribu | 2000 |
Prevention of postoperative vomiting with granisetron in paediatric patients with and without a history of motion sickness.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Child; Disease Susceptibil | 2000 |
[Pharmacotherapy of postoperative pain].
Topics: Acetaminophen; Acute Disease; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Hum | 2000 |
Laparoscopic-assisted colonoscopic polypectomy: the Texas Endosurgery Institute experience.
Topics: Acetaminophen; Adenoma, Villous; Aged; Analgesics, Non-Narcotic; Colonic Neoplasms; Colonic Polyps; | 2000 |
Pharmacokinetics of rectal paracetamol after repeated dosing in children.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Anthropometry; Child; Child, Presch | 2000 |
Rectal paracetamol has a significant morphine-sparing effect after hysterectomy.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Female; Humans; Hysterectomy; Pain, | 2000 |
Pain management practices in children after surgery.
Topics: Acetaminophen; Analgesics; Child; Child, Preschool; Codeine; Drug Administration Routes; Drug Combin | 2000 |
Treatment of postoperative pain in oral and maxillofacial surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics; Anti-Inflammatory | 2000 |
Analgesia following paediatric day-surgical orchidopexy and herniotomy.
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Child; C | 2000 |
Additive analgesia without opioid side effects.
Topics: Acetaminophen; Ambulatory Care; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflam | 2000 |
Audit of pain management at home following tonsillectomy in children.
Topics: Acetaminophen; Adolescent; Analgesics, Non-Narcotic; Analgesics, Opioid; Chi-Square Distribution; Ch | 2001 |
Prospective study of morbidity after tonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Child; Child | 2001 |
Comparative study of diclofenac sodium and paracetamol for treatment of pain after adenotonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-St | 2001 |
Rectal and oral acetaminophen.
Topics: Acetaminophen; Administration, Oral; Administration, Rectal; Analgesics, Non-Narcotic; Female; Human | 2001 |
A comparison of post-operative morbidity following outpatient dental care under general anaesthesia in paediatric patients with and without disabilities.
Topics: Acetaminophen; Adolescent; Ambulatory Care; Analgesics, Non-Narcotic; Anesthesia, Dental; Anesthesia | 2000 |
Elective laparoscopic cholecystectomy.
Topics: Abdominal Pain; Acetaminophen; Acute Disease; Anemia, Sickle Cell; Child; Child, Preschool; Cholecys | 2001 |
Analgesic efficacy of rectal versus oral acetaminophen in children after major craniofacial surgery.
Topics: Acetaminophen; Administration, Oral; Administration, Rectal; Analgesics, Non-Narcotic; Area Under Cu | 2001 |
Acetaminophen analgesia in infants.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Child, Preschool; Humans; Infant | 2001 |
[Cox-2 inhibitors in the focus. Rofecoxib as effective as the "classics"].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2001 |
Children's pain at home following (adeno) tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics; Analgesics, Non-Narcotic; Child; Child Behavio | 2002 |
Children's pain at home following (adeno) tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics; Analgesics, Non-Narcotic; Child; Child Behavio | 2002 |
Children's pain at home following (adeno) tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics; Analgesics, Non-Narcotic; Child; Child Behavio | 2002 |
Children's pain at home following (adeno) tonsillectomy.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics; Analgesics, Non-Narcotic; Child; Child Behavio | 2002 |
'Tears at bedtime' and how to avoid them.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Child; Drug Administration Schedule; Humans; Pain, Postoper | 2002 |
Large dose acetaminophen reconsidered.
Topics: Acetaminophen; Administration, Rectal; Analgesics, Non-Narcotic; Humans; Pain, Postoperative | 2002 |
An audit of post-operative analgesia in children following tonsillectomy.
Topics: Acetaminophen; Adolescent; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Child; Child, Prescho | 2002 |
[Preventive analgesia with acetaminophen in dentistry].
Topics: Acetaminophen; Adolescent; Adult; Aged; Child; Female; Humans; Male; Middle Aged; Mouth; Pain, Posto | 1979 |
Is Tylenol adequate?
Topics: Acetaminophen; Attitude; Humans; Pain, Postoperative; Patients; Periodontium | 1979 |
Dental study shows aspirin substitute more effective than narcotic.
Topics: Acetaminophen; Adolescent; Adult; Codeine; Humans; Pain, Postoperative | 1975 |
Ophthalmic pain following cataract surgery: a comparison between local and general anaesthesia.
Topics: Acetaminophen; Aged; Anesthesia, General; Anesthesia, Local; Cataract Extraction; Female; Humans; Ma | 1992 |
[Prevention and control of pain in (adeno)tonsillectomy].
Topics: Acetaminophen; Adenoidectomy; Child; Child, Preschool; Humans; Pain, Postoperative; Tonsillectomy | 1992 |
Analgesic drug prescription during the spondylodesis by the Harrington rod method.
Topics: Acetaminophen; Adolescent; Adult; Aspirin; Female; Humans; Male; Pain, Postoperative; Spinal Cord | 1992 |
The effect of paracetamol or diclofenac administered before operation on postoperative pain and behaviour after adenoidectomy in small children.
Topics: Acetaminophen; Adenoidectomy; Administration, Rectal; Child Behavior; Child, Preschool; Crying; Dicl | 1992 |
[Postoperative analgesia in France. A study of the prescribing doctor's approach].
Topics: Acetaminophen; Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Dipyrone; Drug Prescriptio | 1992 |
Is fentanyl effective for postoperative analgesia in day-surgery?
Topics: Acetaminophen; Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesia; Anesthesia | 1992 |
[Postoperative analgesia using propacetamol].
Topics: Acetaminophen; Adult; Analgesics; Female; Humans; Infusions, Intravenous; Male; Middle Aged; Pain Me | 1991 |
Effects of acetaminophen after bilateral oral surgery: double dose twice daily versus standard dose four times daily.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Drug Administration Schedule; Edema; Female; Humans; Ma | 1991 |
[Postoperative analgesia for nephrectomy].
Topics: Acetaminophen; Adult; Analgesia, Epidural; Analgesics; Bupivacaine; Buprenorphine; Drug Administrati | 1991 |
[Comparison of analgesic activity of mefenamic acid and paracetamol in treatment of pain after extraction of impacted lower 3d molar].
Topics: Acetaminophen; Adolescent; Adult; Double-Blind Method; Humans; Mandible; Mefenamic Acid; Molar, Thir | 1991 |
Analgesics for dental pain.
Topics: Acetaminophen; Aspirin; Humans; Ibuprofen; Pain, Postoperative; Surgery, Oral | 1991 |
[Perioperative analgesia in the surgery of peripheral veins].
Topics: Acetaminophen; Adult; Aged; Drug Synergism; Female; Humans; Injections, Intravenous; Leg; Male; Midd | 1990 |
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S | 1990 |
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S | 1990 |
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S | 1990 |
Epidural morphine for analgesia after caesarean section: a report of 4880 patients.
Topics: Acetaminophen; Adult; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, Obstetrical; Cesarean S | 1990 |
[Postoperative analgesics consumption].
Topics: Acetaminophen; Codeine; Drug Combinations; Humans; Jaw Fractures; Malocclusion; Osteotomy; Pain, Pos | 1990 |
Analgesic side effects and minor surgery: which analgesic for minor and day-case surgery?
Topics: Acetaminophen; Adult; Ambulatory Surgical Procedures; Analgesics; Codeine; Drug Combinations; Female | 1990 |
Clinical evaluation of FasTENS, an inexpensive, disposable transcutaneous electrical nerve stimulator designed specifically for postoperative electroanalgesia.
Topics: Acetaminophen; Cost-Benefit Analysis; Costs and Cost Analysis; Disposable Equipment; Electric Stimul | 1989 |
[Treatment of postoperative pain in children in the recovery room. Use of morphine and propacetamol by the intravenous route].
Topics: Acetaminophen; Adolescent; Child; Child, Preschool; Female; Humans; Infant; Infusions, Intravenous; | 1989 |
[Which analgesics do you recommend following tonsillectomy?].
Topics: Acetaminophen; Analgesics; Aspirin; Child; Codeine; Drug Combinations; Humans; Pain, Postoperative; | 1989 |
[Activity and tolerance of a paracetamol-codeine combination compared to glafenine in post-operative pain in oral surgery].
Topics: Acetaminophen; Codeine; Drug Combinations; Drug Tolerance; Female; Glafenine; Humans; Male; ortho-Am | 1986 |
Effects of paracetamol and acetylsalicylic acid on the post-operative course after experimental orthopaedic surgery in dogs.
Topics: Acetaminophen; Animals; Aspirin; Dogs; Edema; Female; Forelimb; Inflammation; Male; Pain, Postoperat | 1988 |
Transcutaneous electrical nerve stimulation after cesarean birth.
Topics: Acetaminophen; Adolescent; Adult; Cesarean Section; Codeine; Drug Combinations; Electric Stimulation | 1986 |
Stopayne for postoperative analgesia in plastic surgery patients.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Codeine; Drug Combinations; Drug Evaluation; Hum | 1987 |
Analgesia following arthroscopic surgery: comparison of diflunisal and acetaminophen with codeine.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Codeine; Diflunisal; Drug Combinations; Female; Humans; | 1986 |
Qualitative differences in effects of opioids in man: preliminary evidence for multiple mechanisms of analgesic action.
Topics: Acetaminophen; Codeine; Humans; Isonipecotic Acids; Meperidine; Narcotics; Pain, Postoperative | 1986 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens | 1985 |
[Analgesics in dental practice].
Topics: Acetaminophen; Analgesics; Dental Care; Drug Combinations; Humans; Pain; Pain, Postoperative; Pyrazo | 1985 |
Interrelation of complaints after removal of impacted mandibular third molars.
Topics: Acetaminophen; Adolescent; Adult; Consumer Behavior; Dexamethasone; Edema; Female; Humans; Male; Mol | 1985 |
Sciatic nerve block for children. Sciatic nerve block by the anterior approach for postoperative pain relief.
Topics: Acetaminophen; Adolescent; Child; Child, Preschool; Feasibility Studies; Humans; Infant; Male; Nerve | 1985 |