ondansetron has been researched along with Acute Post-operative Pain in 95 studies
Ondansetron: A competitive serotonin type 3 receptor antagonist. It is effective in the treatment of nausea and vomiting caused by cytotoxic chemotherapy drugs, including cisplatin, and has reported anxiolytic and neuroleptic properties.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This study aimed to evaluate the effectiveness of ramosetron or ondansetron to relieve postoperative nausea and vomiting (PONV) and pain after arthroscopic rotator cuff repair." | 9.34 | The effectiveness of ramosetron and ondansetron for preventing postoperative nausea and vomiting after arthroscopic rotator cuff repair: a randomized controlled trial. ( Kim, YS; Lee, HJ; Lee, SU, 2020) |
| "Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery." | 9.14 | Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010) |
| "Seventy-six percent of the parturients in the placebo group, 87% in the ondansetron, and 79% in the tropisetron group had itching." | 9.12 | Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery. ( Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI, 2006) |
| "In this study we evaluated the efficacy of electro-acupoint stimulation, ondansetron versus placebo for the prevention of postoperative nausea and vomiting (PONV)." | 9.11 | A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting. ( Gan, TJ; Georgiade, G; Jiao, KR; Zenn, M, 2004) |
| "Coinduction with clonidine significantly increased the number of PONV-free patients after breast cancer surgery with general anesthesia." | 9.10 | Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E, 2002) |
| " Intravenous ondansetron and tropisetron prevent postoperative nausea and vomiting (PONV) at least as efficiently as traditional antiemetics, droperidol and metoclopramide." | 9.10 | Oral ondansetron, tropisetron or metoclopramide to prevent postoperative nausea and vomiting: a comparison in high-risk patients undergoing thyroid or parathyroid surgery. ( Alahuhta, S; Jokela, R; Kangas-Saarela, T; Koivuranta, M; Purhonen, S, 2002) |
| "Nalbuphine and ondansetron are more effective than placebo for the prevention of intrathecal morphine-induced pruritus after cesarean delivery." | 9.10 | Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery. ( Charuluxananan, S; Kyokong, O; Narasethakamol, A; Promlok, P; Somboonviboon, W, 2003) |
| "Patients in the ondansetron group reported a lower frequency of total postoperative nausea and vomiting (22%) and lower frequency of rescue antiemetic request (12%) than those in the placebo group (52% and 39%, respectively; P < 0." | 9.10 | Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control. ( Cheng, KI; Chu, KS; Ho, ST; Liu, KS; Tzeng, JI; Wang, JJ, 2003) |
| "Ondansetron has a well documented antiemetic prophylactic effect, whereas in most studies of postoperative nausea and vomiting (PONV), metoclopramide is less efficacious." | 9.10 | Incidence and severity of postoperative nausea and vomiting are similar after metoclopramide 20 mg and ondansetron 8 mg given by the end of laparoscopic cholecystectomies. ( Quaynor, H; Raeder, JC, 2002) |
| ") doses of ondansetron 8 mg, ondansetron 16 mg and metoclopramide 10 mg in the treatment of opioid-induced emesis." | 9.09 | Ondansetron is more effective than metoclopramide for the treatment of opioid-induced emesis in post-surgical adult patients. Ondansetron OIE Post-Surgical Study Group. ( Alahuta, S; Chung, F; Curtis, P; Duvaldestin, P; Jacka, M; Lane, R; Luttropp, HH; McQuade, B; Rocherieux, S; Roy, M; Spraggs, C, 1999) |
| "The efficacy of ondansetron 4 mg was compared with metoclopramide 10 mg for the prevention of post-operative nausea and vomiting in patients after major gynaecological abdominal surgery." | 9.08 | Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. ( Chen, PP; Chui, PT; Gin, T, 1996) |
| "Intravenous ondansetron in a dose of 50 micrograms/kg is as effective as larger doses for the prophylaxis of emesis in children undergoing surgical procedures known to be associated with an increased risk for postoperative nausea and vomiting." | 9.08 | The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery. ( Bras, PJ; Cieslak, GD; Pennant, JH; Watcha, MF, 1995) |
| "PONV was assessed in recovery and 24 hours after surgery in the ward." | 7.01 | Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. ( Aghabagheri, M; Khajavi, MR; Najjari, K; Pourfakhr, P; Talebpour, M; Zabihi Mahmoudabadi, H, 2021) |
| "Ramosetron at 0." | 6.79 | A prospective, randomized, double-blind, and multicenter trial of prophylactic effects of ramosetronon postoperative nausea and vomiting (PONV) after craniotomy: comparison with ondansetron. ( Baik, HJ; Do, SH; Han, JI; Hong, DM; Kim, HZ; Lee, JE; Lim, YJ; Min, KT; Park, HP; Ryu, JH, 2014) |
| "The incidence of postoperative nausea and vomiting was significantly smaller in both groups than predicted according to the patients' underlying risks (midazolam group: p = 0." | 6.73 | Midazolam vs ondansetron for preventing postoperative nausea and vomiting: a randomised controlled trial. ( Chen, A; Lai, HY; Lee, Y; Wang, JJ; Yang, YL, 2007) |
| "The incidence of postoperative nausea and vomiting was 33% for group C, 44% for group O and 41% for group D." | 6.70 | The addition of antiemetics to the morphine solution in patient controlled analgesia syringes used by children after an appendicectomy does not reduce the incidence of postoperative nausea and vomiting. ( Dickson, U; Fisher, S; Morton, N; Munro, FJ, 2002) |
| "Ondansetron is a serotonin (5HT) receptor antagonist at both peripheral and central 5-HT3 receptor sites with no known action on dopamine-mediated activity." | 6.68 | Droperidol/ondansetron combination controls nausea and vomiting after tubal banding. ( Hamilton, DL; McKenzie, R; Riley, TJ; Uy, NT, 1996) |
| "Postoperative pain was treated with morphine, codeine and/or acetaminophen." | 6.68 | Oral ondansetron decreases vomiting after tonsillectomy in children. ( Baxter, MR; Gould, HM; Hall, LE; Komocar, L; MacNeill, HB; Roberts, DJ; Splinter, WM, 1995) |
| " This study aimed to evaluate the effectiveness of ramosetron or ondansetron to relieve postoperative nausea and vomiting (PONV) and pain after arthroscopic rotator cuff repair." | 5.34 | The effectiveness of ramosetron and ondansetron for preventing postoperative nausea and vomiting after arthroscopic rotator cuff repair: a randomized controlled trial. ( Kim, YS; Lee, HJ; Lee, SU, 2020) |
| "Ondansetron appears to be a beneficial and safe method of relieving pruritus associated with intrathecal morphine." | 5.29 | The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients. ( Arai, L; Dorsey, A; Schwartz, R; Stayer, S, 1996) |
| " ondansetron and palonosetron administered at the end of surgery in preventing postoperative nausea and vomiting (PONV) in high-risk patients receiving i." | 5.16 | Anti-emetic effect of ondansetron and palonosetron in thyroidectomy: a prospective, randomized, double-blind study. ( Joo, J; Kim, JE; Lee, Y; Moon, YE, 2012) |
| "Investigators from Bristol described a fentanyl- and diclofenac-based analgesic technique for tonsillectomy with low postoperative nausea and vomiting rates and low pain scores." | 5.15 | A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy*. ( Bagshaw, O; Rawlinson, E; Skone, R; Thillaivasan, A; Walker, A, 2011) |
| "We investigated whether combined dexamethasone and ondansetron is more effective than ondansetron alone in preventing postoperative nausea and vomiting in patients with fentanyl-based intravenous patient-controlled analgesia." | 5.15 | The effect of combining dexamethasone with ondansetron for nausea and vomiting associated with fentanyl-based intravenous patient-controlled analgesia. ( Kang, BC; Lee, JG; Park, EY; Park, YS; Shim, YH; Song, JW, 2011) |
| "Tramadol, a central analgesic acting on serotonin neurotransmission, is often co-used with ondansetron, a 5-HT(3) antagonist, for the management of postoperative pain to decrease nausea and vomiting." | 5.15 | Co-administration of ondansetron decreases the analgesic efficacy of tramadol in humans. ( Assunção, J; Fontes-Ribeiro, C; Oliveira, F; Pereira, F; Vale, C, 2011) |
| "Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery." | 5.14 | Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010) |
| "To compare ondansetron with ondansetron plus prochlorperazine, added to a patient-controlled analgesia (PCA) solution for control of postoperative nausea and vomiting (PONV)." | 5.13 | Patient-controlled analgesia combined with either ondansetron or ondansetron plus prochlorperazine for control of pain and nausea and vomiting in patients undergoing abdominal surgery. ( Fluder, E; Jellish, WS; Owen, K; Sawicki, K; Sinacore, J, 2008) |
| "Seventy-six percent of the parturients in the placebo group, 87% in the ondansetron, and 79% in the tropisetron group had itching." | 5.12 | Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery. ( Halonen, PM; Kainu, JP; Korttila, KT; Sarvela, PJ; Soikkeli, AI, 2006) |
| "In this study we evaluated the efficacy of electro-acupoint stimulation, ondansetron versus placebo for the prevention of postoperative nausea and vomiting (PONV)." | 5.11 | A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting. ( Gan, TJ; Georgiade, G; Jiao, KR; Zenn, M, 2004) |
| "Patients in the ondansetron group reported a lower frequency of total postoperative nausea and vomiting (22%) and lower frequency of rescue antiemetic request (12%) than those in the placebo group (52% and 39%, respectively; P < 0." | 5.10 | Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control. ( Cheng, KI; Chu, KS; Ho, ST; Liu, KS; Tzeng, JI; Wang, JJ, 2003) |
| "Nalbuphine and ondansetron are more effective than placebo for the prevention of intrathecal morphine-induced pruritus after cesarean delivery." | 5.10 | Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery. ( Charuluxananan, S; Kyokong, O; Narasethakamol, A; Promlok, P; Somboonviboon, W, 2003) |
| "Ondansetron has a well documented antiemetic prophylactic effect, whereas in most studies of postoperative nausea and vomiting (PONV), metoclopramide is less efficacious." | 5.10 | Incidence and severity of postoperative nausea and vomiting are similar after metoclopramide 20 mg and ondansetron 8 mg given by the end of laparoscopic cholecystectomies. ( Quaynor, H; Raeder, JC, 2002) |
| "Coinduction with clonidine significantly increased the number of PONV-free patients after breast cancer surgery with general anesthesia." | 5.10 | Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery. ( Bergendahl, HT; Eksborg, S; Lönnqvist, PA; Muhrbeck, O; Oddby-Muhrbeck, E, 2002) |
| " Intravenous ondansetron and tropisetron prevent postoperative nausea and vomiting (PONV) at least as efficiently as traditional antiemetics, droperidol and metoclopramide." | 5.10 | Oral ondansetron, tropisetron or metoclopramide to prevent postoperative nausea and vomiting: a comparison in high-risk patients undergoing thyroid or parathyroid surgery. ( Alahuhta, S; Jokela, R; Kangas-Saarela, T; Koivuranta, M; Purhonen, S, 2002) |
| ") doses of ondansetron 8 mg, ondansetron 16 mg and metoclopramide 10 mg in the treatment of opioid-induced emesis." | 5.09 | Ondansetron is more effective than metoclopramide for the treatment of opioid-induced emesis in post-surgical adult patients. Ondansetron OIE Post-Surgical Study Group. ( Alahuta, S; Chung, F; Curtis, P; Duvaldestin, P; Jacka, M; Lane, R; Luttropp, HH; McQuade, B; Rocherieux, S; Roy, M; Spraggs, C, 1999) |
| "05 mg kg(-1) +droperidol 20 microg kg(-1) was given as prophylaxis for postoperative pain and emesis, respectively." | 5.08 | Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy. ( Aasbø, V; Buanes, T; Grøgaard, B; Mjåland, O; Raeder, JC, 1998) |
| "The efficacy of ondansetron 4 mg was compared with metoclopramide 10 mg for the prevention of post-operative nausea and vomiting in patients after major gynaecological abdominal surgery." | 5.08 | Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery. ( Chen, PP; Chui, PT; Gin, T, 1996) |
| "Intravenous ondansetron in a dose of 50 micrograms/kg is as effective as larger doses for the prophylaxis of emesis in children undergoing surgical procedures known to be associated with an increased risk for postoperative nausea and vomiting." | 5.08 | The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery. ( Bras, PJ; Cieslak, GD; Pennant, JH; Watcha, MF, 1995) |
| "Postoperative nausea and vomiting (PONV) with morphine therapy develops in more than 60% of patients after surgery, markedly reducing patient QOL." | 4.81 | Evaluation of the effective drugs for the prevention of nausea and vomiting induced by morphine used for postoperative pain: a quantitative systematic review. ( Hirayama, T; Ishii, F; Ogata, H; Yago, K, 2001) |
| " When used, the enhanced recovery protocol was associated with a lesser mean amount of ondansetron to treat postoperative nausea and vomiting (5." | 4.02 | A specific enhanced recovery protocol decreases opioid use after thyroid and parathyroid surgery. ( Boisen, ML; Carty, SE; Esper, SA; Holder-Murray, JM; McCoy, KL; Nicholson, KJ; Recker, A; Yip, L, 2021) |
| " Our anesthetic protocol for strabismus surgery included postoperative nausea and vomiting prevention using dexamethasone and ondansetron." | 3.91 | Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery. ( Couret, C; Ducloyer, JB; Le Meur, G; Lebranchu, P; Lejus-Bourdeau, C; Magne, C; Weber, M, 2019) |
| "116 consecutive patients scheduled for breast cancer surgery were prospectively scored according to pain, PONV and sedation after being introduced to a combined evidence-based, empiric multimodal opioid-sparing prevention and treatment regime consisting of Paracetamol, Celecoxib, Dextromethorphan, Gabapetin, Dexamethason and Ondansetron." | 3.74 | [Multimodal treatment of pain and nausea in breast cancer surgery]. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2008) |
| " This study assessed the degree of postoperative pain and nausea when, during the operation, the trocar sites had been infiltrated with bupivacaine and antiemetics (ondansetron) had been administered." | 3.68 | Postoperative pain and nausea after laparoscopic cholecystectomy. ( Jensen, KE; Madsen, MR, 1992) |
| "PONV was assessed in recovery and 24 hours after surgery in the ward." | 3.01 | Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial. ( Aghabagheri, M; Khajavi, MR; Najjari, K; Pourfakhr, P; Talebpour, M; Zabihi Mahmoudabadi, H, 2021) |
| "Ondansetron is a potent anti-emetic drug showing promising results as an analgesic." | 3.01 | Effect of ondansetron compared to lidocaine and placebo for reducing propofol injection pain: A systematic review and meta-analysis of randomized controlled trials. ( AbdelQadir, YH; Adly, MH; Alnaji, AA; Aly, AA; Ammar, MF; Eguzo, MA; Elfar, WH; Elshanbary, AA; Elsnhory, AB; Farhat, AM; Hamza, MM; Hana, K; Hussein, TA; Mahmoud, AM; Morsy, MH; Shah, J; Shamshoon, KF; Zaazouee, MS, 2023) |
| "The incidence of postoperative nausea in women was more than men (p=0." | 2.87 | Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries: A triple blind randomized controlled trial. ( Eshghpour, M; Hashemipour, MS; Hosseini-Abrishami, M; Mianbandi, V; Samieirad, S; Shadkam, E; Sharifian-Attar, A, 2018) |
| "The primary outcome was the incidence of postoperative nausea and vomiting (PONV) during the first postoperative day." | 2.84 | Randomized clinical trial of preoperative dexamethasone on postoperative nausea and vomiting after laparoscopy for suspected appendicitis. ( Gögenur, I; Kirkegaard, A; Kleif, J; Vilandt, J, 2017) |
| "The incidence of PONV and postoperative vomiting was significantly lower (P> ." | 2.82 | Comparison of dexamethasone or intravenous fluids or combination of both on postoperative nausea, vomiting and pain in pediatric strabismus surgery. ( F Riad, MA; M Ali, MO; Sayed, JA, 2016) |
| "The pharmacodynamic interaction between paracetamol and ondansetron coadministration does not block but instead increase paracetamol analgesia, reduce the postoperative analgesic requirement, and improve the postoperative comfort level." | 2.80 | Randomized, double-blind, placebo-controlled study to investigate the pharmacodynamic interaction of 5-HT3 antagonist ondansetron and paracetamol in postoperative patients operated in an ENT department under local anesthesia. ( Bhosale, UA; Kale, J; Khobragade, R; Naik, C; Yegnanarayan, R, 2015) |
| "Ramosetron at 0." | 2.79 | A prospective, randomized, double-blind, and multicenter trial of prophylactic effects of ramosetronon postoperative nausea and vomiting (PONV) after craniotomy: comparison with ondansetron. ( Baik, HJ; Do, SH; Han, JI; Hong, DM; Kim, HZ; Lee, JE; Lim, YJ; Min, KT; Park, HP; Ryu, JH, 2014) |
| "Postoperative pain was treated successfully in both groups." | 2.78 | Ondansetron does not attenuate the analgesic efficacy of nefopam. ( Chen, J; Chen, Y; Li, MG; Lu, KZ; Shen, H; Tian, GP, 2013) |
| "Ramosetron was more effective during the first 24-h period after surgery than ondansetron in children using fentanyl patient-controlled analgesia after general anesthesia." | 2.78 | Comparison of the efficacy of ramosetron and ondansetron in the prophylaxis of postoperative vomiting in children receiving fentanyl by patient-controlled analgesia after orthopedic surgery: a randomized controlled trial. ( Byon, HJ; Jang, YE; Kim, HS; Kim, JT; Park, YH, 2013) |
| "To compare the incidence of postoperative nausea and vomiting (PONV) and postoperative pain in thyroidectomy patients undergoing general anaesthesia, with or without bilateral superficial cervical plexus block (BSCPB)." | 2.77 | Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy. ( Cai, HD; Lin, CZ; Lin, XZ; Yu, CX, 2012) |
| "Of 200 consecutive breast cancer patients, 191 received the full package." | 2.75 | Multimodal prevention of pain, nausea and vomiting after breast cancer surgery. ( Callesen, T; Gärtner, R; Kehlet, H; Kroman, N, 2010) |
| " Acetaminophen (as compared to placebo) in periodic doses starting at induction of anesthesia reduced the total dosage of oxycodone required over 0-24 h (P = 0." | 2.75 | The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy. ( Ahonen, J; Jokela, R; Korttila, K; Marjakangas, P; Seitsonen, E, 2010) |
| "General anaesthesia was performed." | 2.74 | Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial. ( Dahl, JB; Dierking, G; Fomsgaard, JS; Hilsted, KL; Lech, K; Lose, G; Mathiesen, O; Rasmussen, ML, 2009) |
| "The incidence of postoperative nausea and vomiting was significantly smaller in both groups than predicted according to the patients' underlying risks (midazolam group: p = 0." | 2.73 | Midazolam vs ondansetron for preventing postoperative nausea and vomiting: a randomised controlled trial. ( Chen, A; Lai, HY; Lee, Y; Wang, JJ; Yang, YL, 2007) |
| "However, postoperative nausea and vomiting was significantly lower in groups II and III (p < 0." | 2.73 | Postoperative intravenous patient-controlled analgesia in thyroid surgery: comparison of fentanyl and ondansetron regimens with and without the nonsteriodal anti-inflammatory drug ketorolac. ( Chang, DJ; Kim, EM; Kim, KJ; Kim, SY; Nam, KH; Nam, SH, 2008) |
| "Ondansetron was used as an active control." | 2.72 | Supplemental 80% oxygen does not attenuate post-operative nausea and vomiting after breast surgery. ( Hirvonen, E; Hynynen, M; Niskanen, M; Purhonen, S; Wüstefeld, M, 2006) |
| "The incidence of postoperative nausea and vomiting was 33% for group C, 44% for group O and 41% for group D." | 2.70 | The addition of antiemetics to the morphine solution in patient controlled analgesia syringes used by children after an appendicectomy does not reduce the incidence of postoperative nausea and vomiting. ( Dickson, U; Fisher, S; Morton, N; Munro, FJ, 2002) |
| "mL(-1)." | 2.70 | Ondansetron inhibits the analgesic effects of tramadol: a possible 5-HT(3) spinal receptor involvement in acute pain in humans. ( Arcioni, R; della Rocca, M; Gasparetto, A; Pietropaoli, P; Romano, R; Romanò, S, 2002) |
| "Tramadol has weak opioid properties, and an analgesic effect that is mediated mainly by inhibition of the reuptake of norepinephrine and serotonin (5-hydroxytryptamine [5-HT]) and facilitation of 5-HT release (1,2) at the spinal cord." | 2.70 | The analgesic efficacy of tramadol is impaired by concurrent administration of ondansetron. ( De Witte, JL; Deloof, T; Schoenmaekers, B; Sessler, DI, 2001) |
| "Postoperative pain was treated with morphine, codeine and/or acetaminophen." | 2.68 | Oral ondansetron decreases vomiting after tonsillectomy in children. ( Baxter, MR; Gould, HM; Hall, LE; Komocar, L; MacNeill, HB; Roberts, DJ; Splinter, WM, 1995) |
| "Ondansetron is a serotonin (5HT) receptor antagonist at both peripheral and central 5-HT3 receptor sites with no known action on dopamine-mediated activity." | 2.68 | Droperidol/ondansetron combination controls nausea and vomiting after tubal banding. ( Hamilton, DL; McKenzie, R; Riley, TJ; Uy, NT, 1996) |
| " Dose-response relationships show that higher doses of ibuprofen may be particularly effective." | 2.40 | Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review. ( McQuay, HJ; Moore, RA, 1998) |
| " Preanesthetic inhaled ketamine is also reported effective and safe in children." | 1.62 | Preanesthetic nebulized ketamine vs preanesthetic oral ketamine for sedation and postoperative pain management in children for elective surgery: A retrospective analysis for effectiveness and safety. ( Chen, C; Cheng, X; Fu, F; Lin, L, 2021) |
| "Pain and postoperative nausea and vomiting are among the most unpleasant sensations experienced after surgery." | 1.62 | The impact of multimodal therapies on the comfort and safety of patients in the immediate post-anaesthetic period following gynaecological procedures - part I. ( Biskup, A; Merks, P; Plagens-Rotman, K; Polocka-Molinska, M, 2021) |
| "Our preliminary data indicate that postoperative nausea and vomiting may persist into the postdischarge period and pain may be a contributing factor." | 1.51 | An exploratory study of the relationship between postoperative nausea and vomiting and postdischarge nausea and vomiting in children undergoing ambulatory surgery. ( Chandrakantan, A; Jacob, ZC; Jasiewicz, R; Reinsel, RA; Seidman, PA, 2019) |
| "A previous history of postoperative nausea and vomiting (PONV; OR 3." | 1.39 | Incidence and predictors of postdischarge nausea and vomiting in a 7-day population. ( Apfel, CC; Hall, LA; Holtman, J; Hooper, V; Jalota, L; Lennie, TA; Moser, DK; Odom-Forren, J, 2013) |
| "PONV was found in 27 of 47 patients completing the study." | 1.33 | Blood-borne factors possibly associated with post-operative nausea and vomiting: an explorative study in women after breast cancer surgery. ( Bjellerup, P; Eksborg, S; Helander, A; Lindahl, S; Lönnqvist, P; Oddby-Muhrbeck, E, 2005) |
| "Ondansetron appears to be a beneficial and safe method of relieving pruritus associated with intrathecal morphine." | 1.29 | The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients. ( Arai, L; Dorsey, A; Schwartz, R; Stayer, S, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 15 (15.79) | 18.2507 |
| 2000's | 33 (34.74) | 29.6817 |
| 2010's | 38 (40.00) | 24.3611 |
| 2020's | 9 (9.47) | 2.80 |
| Authors | Studies |
|---|---|
| Kim, YS | 2 |
| Lee, CH | 1 |
| Kim, AR | 1 |
| Choi, SS | 1 |
| Lee, MK | 1 |
| Kim, H | 1 |
| Oh, SK | 1 |
| Zaazouee, MS | 1 |
| Mahmoud, AM | 1 |
| Elfar, WH | 1 |
| Hana, K | 1 |
| Shamshoon, KF | 1 |
| Adly, MH | 1 |
| Hussein, TA | 1 |
| Hamza, MM | 1 |
| Aly, AA | 1 |
| Eguzo, MA | 1 |
| Farhat, AM | 1 |
| Elsnhory, AB | 1 |
| Morsy, MH | 1 |
| Ammar, MF | 1 |
| Alnaji, AA | 1 |
| Elshanbary, AA | 1 |
| Shah, J | 1 |
| AbdelQadir, YH | 1 |
| Yip, L | 1 |
| Carty, SE | 1 |
| Holder-Murray, JM | 1 |
| Recker, A | 1 |
| Nicholson, KJ | 1 |
| Boisen, ML | 1 |
| Esper, SA | 1 |
| McCoy, KL | 1 |
| Wang, EHZ | 1 |
| Sunderland, S | 1 |
| Edwards, NY | 1 |
| Chima, NS | 1 |
| Yarnold, CH | 1 |
| Schwarz, SKW | 1 |
| Coley, MA | 1 |
| Lee, SU | 1 |
| Lee, HJ | 1 |
| Biskup, A | 1 |
| Plagens-Rotman, K | 1 |
| Polocka-Molinska, M | 1 |
| Merks, P | 1 |
| Chen, C | 1 |
| Cheng, X | 1 |
| Lin, L | 1 |
| Fu, F | 1 |
| Abdelaziz, DH | 1 |
| Boraii, S | 1 |
| Cheema, E | 1 |
| Elnaem, MH | 1 |
| Omar, T | 1 |
| Abdelraouf, A | 1 |
| Mansour, NO | 1 |
| Pourfakhr, P | 1 |
| Aghabagheri, M | 1 |
| Zabihi Mahmoudabadi, H | 1 |
| Najjari, K | 1 |
| Talebpour, M | 1 |
| Khajavi, MR | 1 |
| Matute Crespo, M | 1 |
| Montero Matamala, A | 1 |
| Cortés-Flores, AO | 1 |
| Jiménez-Tornero, J | 1 |
| Morgan-Villela, G | 1 |
| Delgado-Gómez, M | 1 |
| Zuloaga-Fernández Del Valle, CJ | 1 |
| García-Rentería, J | 1 |
| Rendón-Félix, J | 1 |
| Fuentes-Orozco, C | 1 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| A Double-blinded, Randomized Control Trial of Prophylactic Ondansetron in a Post-operative Cardiac Surgery Population for Post-operative Nausea and Vomiting[NCT02966041] | 186 participants (Actual) | Interventional | 2018-03-06 | Completed | |||
| Triple Combination of Fosaprepitant, Dexamethasone and Palonosetron Versus Combination of Dexamethasone and Palonosetron for the Prevention of Postoperative Nausea and Vomiting in Patients Undergoing Laparoscopic Gastrointestinal Surgery[NCT04853147] | Phase 3 | 1,154 participants (Actual) | Interventional | 2021-04-27 | Completed | ||
| Dexamethasone Preoperative for Patients Undergoing Laparoscopy for Suspected Appendicitis[NCT02415335] | Phase 2 | 119 participants (Actual) | Interventional | 2015-04-30 | Completed | ||
| Antiemetic Prophylaxis for Postdischarge Nausea and Vomiting After Hip Arthroscopy[NCT00878228] | Phase 4 | 98 participants (Actual) | Interventional | 2009-04-30 | Completed | ||
| The Effect of a Preoperative Single-dose Methylprednisolone on the Postoperative Rehabilitation After Abdominal Hysterectomy: A Prospective, Double Blinded, Placebo Controlled Study[NCT01106547] | Phase 4 | 55 participants (Anticipated) | Interventional | 2009-08-31 | Completed | ||
| Preoperative Use of Pregabalin and Analgesia Levels After Laparoscopic Cholecystectomy[NCT01321801] | 50 participants (Actual) | Interventional | 2009-11-30 | Completed | |||
| Double Blinded Study Ondansetron's Opposite Effect on Postoperative Analgesia of Acetaminophen[NCT02296333] | Phase 4 | 80 participants (Actual) | Interventional | 2014-05-31 | Completed | ||
| Role of Scheduled Intravenous Acetaminophen for Postoperative Pain Management in an Enhanced Recovery After Surgery (ERAS) Population: A Prospective, Randomized, Double-Blind and Placebo-Controlled Clinical Trial[NCT03198871] | Phase 4 | 180 participants (Actual) | Interventional | 2018-05-24 | Completed | ||
| Combined General Anesthesia Plus Paravertebral Block Versus General Anesthesia Plus Opioid Analgesia for Breast Cancer Surgery: A Prospective Randomized Trial[NCT01904266] | 60 participants (Actual) | Interventional | 2013-05-31 | Completed | |||
| Multimodal Pain Treatment for Breast Cancer Surgery - a Prospective Cohort Study[NCT04875559] | 236 participants (Actual) | Observational [Patient Registry] | 2021-04-19 | Completed | |||
| Effect of a Multimodal Pain Regimen on Pain Control, Patient Satisfaction and Narcotic Use in Orthopaedic Trauma Patients[NCT02160301] | Phase 4 | 0 participants (Actual) | Interventional | 2017-11-30 | Withdrawn (stopped due to Insufficient infrastructure/funding for enrollment) | ||
| Should we Associate Dexamethasone and Ondansetron to Closed-loop Anesthesia to Reduce the Incidence of Postoperative Nausea and Vomiting After Bariatric Surgery?[NCT01876290] | Phase 4 | 122 participants (Actual) | Interventional | 2013-05-31 | Completed | ||
| ENDOblock: Do Bilateral Superficial Cervical Blocks With Local Wound Infiltration Decrease Postoperative Pain After Thyroid Surgery[NCT05805423] | 74 participants (Anticipated) | Interventional | 2023-04-17 | Recruiting | |||
| Bilateral Superficial Cervical Plexus Block Combined With Intravenous Sedation Versus General Anesthesia in Selected Patients for Thyroid/Parathyroid Surgery ; a Prospective Randomized Control Trial[NCT04051099] | 52 participants (Anticipated) | Interventional | 2018-03-01 | Recruiting | |||
| Effect of Superficial Cervical Plexus Block on Incidence and Severity of Post Operative Nausea and Vomiting in Tympanomastoid Operations in Adults, Randomized Controlled Study[NCT05504551] | 90 participants (Actual) | Interventional | 2022-08-31 | Completed | |||
| Effect of Intravenous Granisetron on Incidence and Severity of Intrathecal Morphine Induced Pruritus in Elective Cesarean Section[NCT03483870] | Phase 2 | 80 participants (Actual) | Interventional | 2018-06-01 | Completed | ||
| Quality of Recovery Following Administration of Transverse Abdominus Plane (TAP) Catheter as Compared to Intrathecal Morphine After Cesarean Delivery Under Spinal Anesthesia: a Prospective, Randomized Trial[NCT01593280] | 80 participants (Anticipated) | Interventional | 2012-05-31 | Recruiting | |||
| The Effect of Electroacustimulation on Postoperative Nausea, Vomiting and Pain in Outpatient Plastic Surgery Patients: A Prospective, Randomized, Blinded Clinical Trial[NCT00941005] | 122 participants (Actual) | Interventional | 2008-01-31 | Completed | |||
| Is Intra-operative Acupuncture Point P6 Stimulation as Effective as Traditional Pharmacotherapy in Reducing Nausea and Vomiting During Cesarean Section With Regional Anesthesia?[NCT02959840] | Phase 4 | 180 participants (Actual) | Interventional | 2015-07-31 | Completed | ||
| IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777] | Phase 2/Phase 3 | 68 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| The Effects of Scalp Block on Haemodynamic Response and Postoperative Pain in[NCT02852382] | Phase 2 | 45 participants (Actual) | Interventional | 2014-04-30 | Completed | ||
| Postoperative Pain and Headache After Craniotomy[NCT03908944] | Phase 2 | 0 participants (Actual) | Interventional | 2019-01-02 | Withdrawn (stopped due to PI- Dr. Jellish passed away. The study was terminated with the IRB) | ||
| Effect of Postoperative Trendelenburg Position on Shoulder Pain After Gynecological Laparoscopic Procedures.[NCT04129385] | 108 participants (Actual) | Interventional | 2016-03-01 | Completed | |||
| The Effect of Hot Application on Shoulder Pain and Analgesic Use After Laparoscopic Upper Abdominal Surgery[NCT05334797] | 60 participants (Anticipated) | Interventional | 2022-04-12 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Percentage of participants whose quality of life was impacted by nausea and vomiting (NCT00878228)
Timeframe: Postdischarge Day 1
| Intervention | percentage of participants (Number) |
|---|---|
| Study Group | 18 |
| Control Group | 30 |
Percentage of participants with nausea (NCT00878228)
Timeframe: Postdischarge Day 1
| Intervention | percentage of participants (Number) |
|---|---|
| Study Group | 46 |
| Control Group | 54 |
Percentage of participants reporting moderate or severe nausea in the first 24 hours (NCT00878228)
Timeframe: Postdischarge Day 1
| Intervention | percentage of participants (Number) |
|---|---|
| Study Group | 23 |
| Control Group | 32 |
Number of patients who score greater than a 4 on the 0-8 point ICDSC scale to assess delirium scores. 8 separate levels of signs for delirium assessed (1. altered level of consciousness, 2. inattention, 3. disorientation, 4. hallucination, delusion, or psychosis, 5. psychomotor agitation or retardation, 6. inappropriate speech or mood, 7. sleep-wake cycle disturbance, 8. symptom fluctuation), with 0 points awarded when patient does not exhibit above signs of delirium and 1 point awarded per confirmed sign of delirium. Score then totaled, 0 = normal, 1-3 = subsyndromal delirium, 4-8 = delirium. (NCT03198871)
Timeframe: The delirium scores will first be measured every 12 hours for 72 hours after surgery.
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 0 |
| Sodium Chloride 0.9%, Intravenous | 0 |
If the patient is readmitted to the hospital after being fully discharged, the event will be recorded. (NCT03198871)
Timeframe: From the time of consent until 30 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 9 |
| Sodium Chloride 0.9%, Intravenous | 10 |
Number of patients with unsatisfactory pain relief defined as average numeric rating scale (NRS) more than 5 will be compared between the two groups. This may include patients using IVPCA for pain relief during the first 48 hours postoperative. (NCT03198871)
Timeframe: PACU admission every thirty minutes until discharge to the floor and thereafter every four hours for first 24-hour, then every six hours until 48 hours and then every twelve hours until 72 hours postoperatively.
| Intervention | Participants (Count of Participants) |
|---|---|
| Acetaminophen Injectable Product | 33 |
| Sodium Chloride 0.9%, Intravenous | 42 |
The time it takes for the patient to successfully ambulate post-surgery will be measured. (NCT03198871)
Timeframe: From date of PACU admission until the date of first documented ambulation, assessed up to 72 hours postoperatively
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 18.82 |
| Sodium Chloride 0.9%, Intravenous | 17.38 |
The time it takes for the first bowel movement postoperatively will be measured. (NCT03198871)
Timeframe: From time patient left operating room until the time of first documented bowel movement, assessed up to hospital discharge
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 46.30 |
| Sodium Chloride 0.9%, Intravenous | 64.66 |
The time it takes for the patient to be fully discharged from the hospital post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of hospital discharge or 30 days postoperatively, whichever comes first
| Intervention | days (Median) |
|---|---|
| Acetaminophen Injectable Product | 4.08 |
| Sodium Chloride 0.9%, Intravenous | 4.94 |
The time it takes for the patient to ingest orally post-surgery will be measured. (NCT03198871)
Timeframe: From date of randomization until the date of first documented oral intake, assessed up to 72 hours postoperatively
| Intervention | hours (Median) |
|---|---|
| Acetaminophen Injectable Product | 12.15 |
| Sodium Chloride 0.9%, Intravenous | 9.40 |
The time from PACU admission to PACU discharge to the floor will be measured. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge, assessed up to 24 hours postoperatively
| Intervention | minutes (Median) |
|---|---|
| Acetaminophen Injectable Product | 129.00 |
| Sodium Chloride 0.9%, Intravenous | 152.50 |
Overall patient satisfaction as well as satisfaction relating to pain management and cost analyses will be measured. These will be measured with a numerical rating scale (NRS) with 0- being worst satisfaction and 10 - best satisfaction. (NCT03198871)
Timeframe: These measurements will be taken at time of discharge up to 30 days, whichever comes first
| Intervention | score on a scale (Median) | |
|---|---|---|
| Patient satisfaction score, overall | Patient Satisfaction score, pain management | |
| Acetaminophen Injectable Product | 10 | 10 |
| Sodium Chloride 0.9%, Intravenous | 10 | 10 |
Frequency of emesis and rescue antiemetic requirement will be documented (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.
| Intervention | Participants (Count of Participants) | |
|---|---|---|
| Emesis incidence 0-72 hours | Antiemetic use | |
| Acetaminophen Injectable Product | 12 | 31 |
| Sodium Chloride 0.9%, Intravenous | 14 | 45 |
Nausea will be evaluated by nausea score from 0 to 10, with 0 equaling no nausea and 10 equaling the worst nausea imaginable. (NCT03198871)
Timeframe: These will be evaluated from the time of PACU admission until 72 hours postoperatively.
| Intervention | score on a scale (Mean) | |||||
|---|---|---|---|---|---|---|
| Nausea score POD 1 (am visit) | Nausea score POD 1 (pm visit) | Nausea score POD 2 (am visit) | Nausea score POD 2 (pm visit) | Nausea score POD 3 (am visit) | Nausea score POD 3 (pm visit) | |
| Acetaminophen Injectable Product | 1.13 | 0.49 | 0.71 | 0.55 | 0.32 | 0.56 |
| Sodium Chloride 0.9%, Intravenous | 0.60 | 0.92 | 0.75 | 0.69 | 0.66 | 0.78 |
Survey to assess patient's overall health (via a combination of mental and physical health assessment) at 30 days post-discharge. Two summary scores are reported from the SF-12 - a mental component score (MCS-12) and a physical component score (PCS-12). The scores may be reported as Z-scores (difference compared to the population average, measured in standard deviations). The United States population average PCS-12 and MCS-12 are both 50 points. The United States population standard deviation is 10 points. So each 10 increment of 10 points above or below 50, corresponds to one standard deviation away from the average (NCT03198871)
Timeframe: These measurements will take place at 30-days post hospital discharge
| Intervention | Z-scores (difference compared to the pop (Median) | |
|---|---|---|
| SF 12 Physical score | SF 12 Mental score | |
| Acetaminophen Injectable Product | 38.72 | 54.02 |
| Sodium Chloride 0.9%, Intravenous | 38.07 | 52.08 |
Rescue analgesia will be given according to institutional pain management protocol. Unit of Measure recorded as OME (Oral Morphine Equivalent) consumption in mg. (NCT03198871)
Timeframe: From time of PACU admission until the time of discharge and 72-hours postoperatively, whichever comes first
| Intervention | mg (Median) | ||||
|---|---|---|---|---|---|
| 0-24 hours | 24-48 hours | 48-72 hours | 0-48 hours | 0-72 hours | |
| Acetaminophen Injectable Product | 27.4 | 31.3 | 30 | 74 | 105.00 |
| Sodium Chloride 0.9%, Intravenous | 36 | 45 | 37.5 | 88.8 | 127.1 |
(NCT00941005)
Timeframe: 24 hours
| Intervention | incidence of emetic events (Mean) |
|---|---|
| Electroacustimulation | 0 |
| Control | 0 |
Phone survey of post-op pain medication usage was administered on postoperative day 1. (NCT00941005)
Timeframe: 24 hours post-op
| Intervention | Participants (Count of Participants) |
|---|---|
| Electroacustimulation | NA |
| Control | NA |
(NCT00941005)
Timeframe: 24 hours
| Intervention | Participants (Count of Participants) |
|---|---|
| Electroacustimulation | NA |
| Control | NA |
Phone survey of nausea/vomiting symptoms was administered on postoperative day 1. The survey consists of 8 questions, including: 1) a query about whether or not participant has experienced nausea since returning home; 2) rate nausea severity on a scale of 1-10 (where 10 is the most severe); 3) a query about satisfaction of nausea control; 4) a question asking if they would use the same post-op nausea treatment again; 5) a query about what activities the participant has been unable to do since surgery; 6) whether or not the participant has taken prescription medicine for treatment of nausea since returning home; 7) whether or not participant has taken prescription medicine for treatment of pain since returning home; and 8) if yes for 6-7, which medications. (NCT00941005)
Timeframe: 24 hours post-op
| Intervention | score on a scale (Mean) |
|---|---|
| Electroacustimulation | NA |
| Control | NA |
(NCT00941005)
Timeframe: 24 hours
| Intervention | minutes (Mean) |
|---|---|
| Electroacustimulation | NA |
| Control | NA |
Nausea is scored on a scale of 1-10 where 1 is least nauseated and 10 is severely nauseated. Nausea scores will be collected 30, 60, and 120 minutes after surgery. (NCT00941005)
Timeframe: 24 hours
| Intervention | participants (Number) | ||
|---|---|---|---|
| 30 min post-op | 60 min post-op | 120 min post-op | |
| Control | NA | NA | NA |
| Electroacustimulation | NA | NA | NA |
Participants will evaluate their postoperative pain score on a scale of 1-10 where 1 is the least pain and 10 is the most severe pain. Pain scores will be evaluated at 30, 60, and 120 minutes postop. (NCT00941005)
Timeframe: 24 hours
| Intervention | score on a scale (Mean) | ||
|---|---|---|---|
| 30 min post-op | 60 min post-op | 120 min post-op | |
| Control | NA | NA | NA |
| Electroacustimulation | NA | NA | NA |
The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea at any point during the surgical procedure in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 44 |
| Metoclopramide, Ondansetron | 14 |
| Acupressure Point P6 Stimulator | 22 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage I. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 33 |
| Metoclopramide, Ondansetron | 7 |
| Acupressure Point P6 Stimulator | 14 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage II. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 12 |
| Metoclopramide, Ondansetron | 6 |
| Acupressure Point P6 Stimulator | 5 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage III. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 16 |
| Metoclopramide, Ondansetron | 8 |
| Acupressure Point P6 Stimulator | 14 |
Patients offer their subjective assessments of the level of nausea on a scale of 0-10 (0 = no nausea, 10 = worst nausea ever experienced) during stage IV. The investigators will analyze if there is a statistically significant difference between the number of patients that experience nausea in each group at this point. Patients that report nausea (1 or more on our scale) will be recorded as that they have experienced nausea. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 3 |
| Metoclopramide, Ondansetron | 4 |
| Acupressure Point P6 Stimulator | 0 |
Patients are asked their overall anesthetic care satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Data are expressed as number of parturients who gave a score of 8 or higher. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 53 |
| Metoclopramide, Ondansetron | 58 |
| Acupressure Point P6 Stimulator | 56 |
Patients are asked their anti-emetic treatment satisfaction (0 = Not Satisfied, 10 = Extremely Satisfied). Data are expressed as number of parturients who gave a score of 8 or higher. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 49 |
| Metoclopramide, Ondansetron | 58 |
| Acupressure Point P6 Stimulator | 55 |
The investigators will perform objective assessments of whether or not the patients have vomited during the procedure. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 27 |
| Metoclopramide, Ondansetron | 10 |
| Acupressure Point P6 Stimulator | 8 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage I. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 20 |
| Metoclopramide, Ondansetron | 5 |
| Acupressure Point P6 Stimulator | 4 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage II. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 10 |
| Metoclopramide, Ondansetron | 1 |
| Acupressure Point P6 Stimulator | 3 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage III. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 9 |
| Metoclopramide, Ondansetron | 4 |
| Acupressure Point P6 Stimulator | 6 |
The investigators will perform objective assessments of whether or not the patients have vomited during stage IV. The investigators will then analyze if there is a statistically significant difference between the number of patients that vomit in each group. (NCT02959840)
Timeframe: During the surgical procedure
| Intervention | Participants (Count of Participants) |
|---|---|
| Control | 0 |
| Metoclopramide, Ondansetron | 2 |
| Acupressure Point P6 Stimulator | 0 |
5 reviews available for ondansetron and Acute Post-operative Pain
| Article | Year |
|---|---|
Effect of ondansetron compared to lidocaine and placebo for reducing propofol injection pain: A systematic review and meta-analysis of randomized controlled trials.
Topics: Humans; Lidocaine; Ondansetron; Pain, Postoperative; Propofol; Randomized Controlled Trials as Topic | 2023 |
The effect of ondansetron on the efficacy of postoperative tramadol: a systematic review and meta-analysis of a drug interaction.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Drug Interactions; Humans; Ondansetr | 2015 |
[Patient-controlled analgesia. Pain and Locoregional Anesthesia Committee and the Standards Committee of the French Society of Anesthesia and Intensive Care].
Topics: Analgesia, Patient-Controlled; Antiemetics; Droperidol; Drug Administration Routes; Drug Synergism; | 2009 |
Postoperative analgesia and vomiting, with special reference to day-case surgery: a systematic review.
Topics: Acetaminophen; Ambulatory Surgical Procedures; Analgesia; Analgesics, Non-Narcotic; Analgesics, Opio | 1998 |
Evaluation of the effective drugs for the prevention of nausea and vomiting induced by morphine used for postoperative pain: a quantitative systematic review.
Topics: Antiemetics; Dexamethasone; Droperidol; Humans; Metoclopramide; Morphine; Ondansetron; Pain, Postope | 2001 |
64 trials available for ondansetron and Acute Post-operative Pain
| Article | Year |
|---|---|
A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial.
Topics: Aged; Antiemetics; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double | 2020 |
A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial.
Topics: Aged; Antiemetics; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double | 2020 |
A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial.
Topics: Aged; Antiemetics; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double | 2020 |
A Single Prophylactic Dose of Ondansetron Given at Cessation of Postoperative Propofol Sedation Decreases Postoperative Nausea and Vomiting in Cardiac Surgery Patients: A Randomized Controlled Trial.
Topics: Aged; Antiemetics; Arrhythmias, Cardiac; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Double | 2020 |
The effectiveness of ramosetron and ondansetron for preventing postoperative nausea and vomiting after arthroscopic rotator cuff repair: a randomized controlled trial.
Topics: Aged; Antiemetics; Arthroscopy; Benzimidazoles; Female; Humans; Infusions, Intravenous; Male; Middle | 2020 |
The intraperitoneal ondansetron for postoperative pain management following laparoscopic cholecystectomy: A proof-of-concept, double-blind, placebo-controlled trial.
Topics: Acetaminophen; Adjuvants, Pharmaceutic; Adult; Analgesics; Antiemetics; Cholecystectomy, Laparoscopi | 2021 |
Prophylactic Administration of Diphenhydramine/Acetaminophen and Ondansetron Reduced Postoperative Nausea and Vomiting and Pain Following Laparoscopic Sleeve Gastrectomy: a Randomized Controlled Trial.
Topics: Acetaminophen; Antiemetics; Diphenhydramine; Double-Blind Method; Gastrectomy; Humans; Laparoscopy; | 2021 |
Effects of preoperative dexamethasone on postoperative pain, nausea, vomiting and respiratory function in women undergoing conservative breast surgery for cancer: Results of a controlled clinical trial.
Topics: Adenocarcinoma; Adult; Aged; Analgesics, Opioid; Antiemetics; Breast Neoplasms; Dexamethasone; Doubl | 2018 |
The effect of ondansetron on analgesic efficacy of acetaminophen after hysterectomy: A randomized double blinded placebo controlled trial.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Antiemetics; Double-Blind Method | 2017 |
Comparison of Ondansetron versus Clonidine efficacy for prevention of postoperative pain, nausea and vomiting after orthognathic surgeries: A triple blind randomized controlled trial.
Topics: Adolescent; Adult; Analgesics; Antiemetics; Clonidine; Double-Blind Method; Female; Humans; Male; On | 2018 |
The effect of ondansetron on postoperative delirium and cognitive function in aged orthopedic patients.
Topics: Aged; Anesthesia, General; Cognition Disorders; Delirium; Double-Blind Method; Female; Femoral Fract | 2014 |
Ondansetron does not attenuate the analgesic efficacy of nefopam.
Topics: Adult; Aged; Analgesics; Drug Combinations; Drug-Related Side Effects and Adverse Reactions; Female; | 2013 |
A prospective, randomized, double-blind, and multicenter trial of prophylactic effects of ramosetronon postoperative nausea and vomiting (PONV) after craniotomy: comparison with ondansetron.
Topics: Adult; Aged; Antiemetics; Benzimidazoles; Craniotomy; Double-Blind Method; Female; Humans; Male; Mid | 2014 |
Analgesic interaction between ondansetron and acetaminophen after tonsillectomy in children: the Paratron randomized, controlled trial.
Topics: Acetaminophen; Adenoidectomy; Adjuvants, Anesthesia; Analgesics, Non-Narcotic; Analgesics, Opioid; A | 2015 |
Randomized, double-blind, placebo-controlled study to investigate the pharmacodynamic interaction of 5-HT3 antagonist ondansetron and paracetamol in postoperative patients operated in an ENT department under local anesthesia.
Topics: Acetaminophen; Analgesics; Anesthesia, Local; Double-Blind Method; Female; Humans; Male; Middle Aged | 2015 |
[Influence of dexamethasone on the incidence of postoperative nausea and vomiting in breast cancer patients with neoadjuvant chemotherapy].
Topics: Adolescent; Adult; Anesthesia, General; Anesthesia, Intravenous; Anesthetics, Intravenous; Antiemeti | 2015 |
Comparison of dexamethasone or intravenous fluids or combination of both on postoperative nausea, vomiting and pain in pediatric strabismus surgery.
Topics: Administration, Intravenous; Antiemetics; Child; Dexamethasone; Double-Blind Method; Drug Therapy, C | 2016 |
Randomized clinical trial of preoperative dexamethasone on postoperative nausea and vomiting after laparoscopy for suspected appendicitis.
Topics: Acute Disease; Administration, Oral; Adult; Antiemetics; Appendectomy; Appendicitis; Dexamethasone; | 2017 |
Antiemetic prophylaxis for postdischarge nausea and vomiting and impact on functional quality of living during recovery in patients with high emetic risks: a prospective, randomized, double-blind comparison of two prophylactic antiemetic regimens.
Topics: Administration, Oral; Adult; Ambulatory Surgical Procedures; Antiemetics; Dexamethasone; Double-Blin | 2008 |
Postoperative intravenous patient-controlled analgesia in thyroid surgery: comparison of fentanyl and ondansetron regimens with and without the nonsteriodal anti-inflammatory drug ketorolac.
Topics: Adult; Analgesia, Patient-Controlled; Anti-Inflammatory Agents, Non-Steroidal; Dizziness; Female; Fe | 2008 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Pregabalin and dexamethasone in combination with paracetamol for postoperative pain control after abdominal hysterectomy. A randomized clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dexamethasone; Double | 2009 |
Patient-controlled analgesia combined with either ondansetron or ondansetron plus prochlorperazine for control of pain and nausea and vomiting in patients undergoing abdominal surgery.
Topics: Abdomen; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Double-Blind Method; | 2008 |
Haloperidol versus haloperidol plus ondansetron for the prophylaxis of postoperative nausea and vomiting after ophthalmologic surgery.
Topics: Double-Blind Method; Drug Therapy, Combination; Female; Haloperidol; Humans; Middle Aged; Ondansetro | 2009 |
Ondansetron added to lidocaine for intravenous regional anaesthesia.
Topics: Adult; Anesthesia, Conduction; Anesthetics, Local; Double-Blind Method; Female; Hand; Humans; Inject | 2009 |
Does single-dose preoperative dexamethasone minimize stress response and improve recovery after laparoscopic cholecystectomy?
Topics: Adult; Anti-Inflammatory Agents; Antiemetics; C-Reactive Protein; Cholecystectomy, Laparoscopic; Dex | 2009 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
The influence of ondansetron on the analgesic effect of acetaminophen after laparoscopic hysterectomy.
Topics: Acetaminophen; Adult; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid; D | 2010 |
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery.
Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Hum | 2010 |
Anti-emetic effect of midazolam added to morphine patient-controlled analgesia after total abdominal hysterectomy.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Female; Humans; Hysterectomy; | 2010 |
Prophylactic control of post-operative nausea and vomiting using ondansetron and ramosetron after cardiac surgery.
Topics: Aged; Analgesia, Patient-Controlled; Anesthesia; Antiemetics; Benzimidazoles; Cardiac Surgical Proce | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal prevention of pain, nausea and vomiting after breast cancer surgery.
Topics: Acetaminophen; Aged; Amines; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthesia, Intra | 2010 |
Multimodal approach to postoperative pain control in patients undergoing rotator cuff repair.
Topics: Acetaminophen; Adult; Aged; Analgesia, Patient-Controlled; Analgesics; Arthroscopy; Cyclooxygenase 2 | 2011 |
The effect of combining dexamethasone with ondansetron for nausea and vomiting associated with fentanyl-based intravenous patient-controlled analgesia.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Dexamethasone; Drug The | 2011 |
Ondansetron does not modify emergence agitation in children.
Topics: Anesthesia Recovery Period; Anesthesia, Inhalation; Anesthetics, Inhalation; Anxiety; Child; Child, | 2011 |
A randomised controlled trial of two analgesic techniques for paediatric tonsillectomy*.
Topics: Acetaminophen; Analgesics; Analgesics, Opioid; Anesthetics, Inhalation; Anesthetics, Intravenous; An | 2011 |
Co-administration of ondansetron decreases the analgesic efficacy of tramadol in humans.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Double-Blin | 2011 |
Anti-emetic effect of ondansetron and palonosetron in thyroidectomy: a prospective, randomized, double-blind study.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Bilateral superficial cervical plexus block reduces postoperative nausea and vomiting and early postoperative pain after thyroidectomy.
Topics: Adult; Amides; Analgesics; Analysis of Variance; Anesthetics, Local; Antiemetics; Autonomic Nerve Bl | 2012 |
Comparison of the efficacy of ramosetron and ondansetron in the prophylaxis of postoperative vomiting in children receiving fentanyl by patient-controlled analgesia after orthopedic surgery: a randomized controlled trial.
Topics: Adolescent; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Benzimidazoles; Child; C | 2013 |
The addition of antiemetics to the morphine solution in patient controlled analgesia syringes used by children after an appendicectomy does not reduce the incidence of postoperative nausea and vomiting.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Antiemetics; Appendectomy; C | 2002 |
Ondansetron disintegrating tablets of 8 mg twice a day for 3 days did not reduce the incidence of nausea or vomiting after laparoscopic surgery.
Topics: Administration, Oral; Adult; Antiemetics; Cholecystectomy; Double-Blind Method; Female; Fundoplicati | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Nalbuphine versus ondansetron for prevention of intrathecal morphine-induced pruritus after cesarean delivery.
Topics: Adult; Analgesics, Opioid; Cesarean Section; Double-Blind Method; Female; Humans; Morphine; Nalbuphi | 2003 |
Prophylactic iv ondansetron reduces nausea, vomiting and pruritus following epidural morphine for postoperative pain control.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Antiemetics; Double-Blind Method; Female; Humans; H | 2003 |
A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting.
Topics: Adult; Aged; Analgesia; Antiemetics; Breast Neoplasms; Electroacupuncture; Female; Humans; Middle Ag | 2004 |
A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting.
Topics: Adult; Aged; Analgesia; Antiemetics; Breast Neoplasms; Electroacupuncture; Female; Humans; Middle Ag | 2004 |
A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting.
Topics: Adult; Aged; Analgesia; Antiemetics; Breast Neoplasms; Electroacupuncture; Female; Humans; Middle Ag | 2004 |
A randomized controlled comparison of electro-acupoint stimulation or ondansetron versus placebo for the prevention of postoperative nausea and vomiting.
Topics: Adult; Aged; Analgesia; Antiemetics; Breast Neoplasms; Electroacupuncture; Female; Humans; Middle Ag | 2004 |
Ondansetron and tropisetron do not prevent intraspinal morphine- and fentanyl-induced pruritus in elective cesarean delivery.
Topics: Adult; Analgesics, Opioid; Anesthesia, Epidural; Anesthesia, Spinal; Anti-Inflammatory Agents, Non-S | 2006 |
Supplemental 80% oxygen does not attenuate post-operative nausea and vomiting after breast surgery.
Topics: Adolescent; Adult; Aged; Anesthetics, Inhalation; Antiemetics; Female; Humans; Mammaplasty; Mastecto | 2006 |
Morphine/ondansetron PCA for postoperative pain, nausea, and vomiting after skull base surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Blood Press | 2006 |
Morphine/ondansetron PCA for postoperative pain, nausea, and vomiting after skull base surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Blood Press | 2006 |
Morphine/ondansetron PCA for postoperative pain, nausea, and vomiting after skull base surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Blood Press | 2006 |
Morphine/ondansetron PCA for postoperative pain, nausea, and vomiting after skull base surgery.
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Blood Press | 2006 |
Midazolam vs ondansetron for preventing postoperative nausea and vomiting: a randomised controlled trial.
Topics: Adjuvants, Anesthesia; Adolescent; Adult; Aged; Anesthesia Recovery Period; Anesthesia, General; Ane | 2007 |
[Effect of ondansetron in lower extremity bone surgery on morphine and tramadol consumption using patient controlled analgesia].
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Anxiety Agents; Bone Diseases; Drug A | 2007 |
[Cost-effectiveness analysis of patient-controlled analgesia compared to continuous elastomeric pump infusion of tramadol and metamizole].
Topics: Adolescent; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Non-Narcotic; Analgesics, Opioid | 2007 |
The effects of preoperative rofecoxib, metoclopramide, dexamethasone, and ondansetron on postoperative pain and nausea in patients undergoing elective laparoscopic cholecystectomy.
Topics: Antiemetics; Cholecystectomy, Laparoscopic; Cyclooxygenase 2 Inhibitors; Dexamethasone; Double-Blind | 2007 |
Resumption of daily physical activity after day-case laparoscopic cholecystectomy.
Topics: Activities of Daily Living; Adult; Ambulatory Surgical Procedures; Analgesics; Cholecystectomy, Lapa | 2009 |
Oral ondansetron decreases vomiting after tonsillectomy in children.
Topics: Administration, Oral; Adolescent; Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesth | 1995 |
The dose-response relationship of ondansetron in preventing postoperative emesis in pediatric patients undergoing ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia, General; Child; Child, Preschool; Dose-Response Relation | 1995 |
[Postoperative pain therapy. The efficacy of a serotonin antagonist (GR 38032F;ondansetron) and the prostaglandin synthesis inhibitor lysin acetylsalicylate (Aspisol)].
Topics: Adult; Analgesics; Aspirin; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Lysine; | 1993 |
A comparison of costs and efficacy of ondansetron and droperidol as prophylactic antiemetic therapy for elective outpatient gynecologic procedures.
Topics: Activities of Daily Living; Adult; Ambulatory Surgical Procedures; Antiemetics; Anxiety; Conscious S | 1996 |
Antiemetic efficacy of ondansetron with patient-controlled analgesia.
Topics: Adult; Analgesia, Patient-Controlled; Antiemetics; Double-Blind Method; Female; Humans; Hysterectomy | 1996 |
Comparison of ondansetron and metoclopramide for the prevention of post-operative nausea and vomiting after major gynaecological surgery.
Topics: Adolescent; Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; Humans; Hysterectom | 1996 |
Droperidol/ondansetron combination controls nausea and vomiting after tubal banding.
Topics: Antiemetics; Dopamine Antagonists; Double-Blind Method; Droperidol; Drug Combinations; Female; Human | 1996 |
Comparison of metoclopramide and ondansetron for the prevention of nausea and vomiting after intrathecal morphine.
Topics: Aged; Analgesics, Opioid; Antiemetics; Blood Pressure; Double-Blind Method; Female; Hip; Humans; Inj | 1997 |
Desflurane versus propofol maintenance for outpatient laparoscopic cholecystectomy.
Topics: Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Anesthesia Recovery Period; Anesthetics, D | 1998 |
The use of tramadol following day--case oral surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; | 1999 |
Ondansetron is more effective than metoclopramide for the treatment of opioid-induced emesis in post-surgical adult patients. Ondansetron OIE Post-Surgical Study Group.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Antiemetics; Double-Blind Method; Fe | 1999 |
The analgesic efficacy of tramadol is impaired by concurrent administration of ondansetron.
Topics: Adult; Analgesics, Opioid; Antiemetics; Drug Interactions; Female; Humans; Laminectomy; Male; Middle | 2001 |
Incidence and severity of postoperative nausea and vomiting are similar after metoclopramide 20 mg and ondansetron 8 mg given by the end of laparoscopic cholecystectomies.
Topics: Anesthesia, General; Antiemetics; Cholecystectomy, Laparoscopic; Double-Blind Method; Female; Humans | 2002 |
Effects of clonidine on postoperative nausea and vomiting in breast cancer surgery.
Topics: Adrenergic alpha-Agonists; Aged; Anesthesia, General; Antiemetics; Blood Pressure; Breast Neoplasms; | 2002 |
Oral ondansetron, tropisetron or metoclopramide to prevent postoperative nausea and vomiting: a comparison in high-risk patients undergoing thyroid or parathyroid surgery.
Topics: Adult; Analgesics, Opioid; Antiemetics; Double-Blind Method; Female; Humans; Indoles; Male; Metoclop | 2002 |
Ondansetron inhibits the analgesic effects of tramadol: a possible 5-HT(3) spinal receptor involvement in acute pain in humans.
Topics: Acute Disease; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Drug Interactio | 2002 |
26 other studies available for ondansetron and Acute Post-operative Pain
| Article | Year |
|---|---|
Microbiological and Physicochemical Stability of Fentanyl, Oxycodone, Hydromorphone, Ketorolac, Ramosetron, and Ondansetron for Intravenous Patient-controlled Analgesia: An In Vitro Study.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Benzimidazoles; Fentanyl; Humans; Hydromorphone; | 2021 |
A specific enhanced recovery protocol decreases opioid use after thyroid and parathyroid surgery.
Topics: Adult; Aged; Analgesics, Opioid; Drug Utilization; Enhanced Recovery After Surgery; Female; Health P | 2021 |
The impact of multimodal therapies on the comfort and safety of patients in the immediate post-anaesthetic period following gynaecological procedures - part I.
Topics: Adult; Analgesics, Opioid; Anesthetics; Antiemetics; Female; Gynecologic Surgical Procedures; Humans | 2021 |
Preanesthetic nebulized ketamine vs preanesthetic oral ketamine for sedation and postoperative pain management in children for elective surgery: A retrospective analysis for effectiveness and safety.
Topics: Analgesics; Antiemetics; Child; Child, Preschool; Elective Surgical Procedures; Female; Humans; Keta | 2021 |
Pharmacological advances in the multimodal management of perioperative analgesia.
Topics: Analgesia; Analgesics; Analgesics, Opioid; Clinical Trials as Topic; Combined Modality Therapy; Dexm | 2017 |
Prospective evaluation of anesthetic protocols during pediatric ophthalmic surgery.
Topics: Acetaminophen; Anesthesia, Local; Anesthetics, Combined; Anesthetics, Intravenous; Anti-Anxiety Agen | 2019 |
[Parent controled analgesia system in postoperative pain management in patients undergoing lip and cleft palate surgery].
Topics: Analgesia, Patient-Controlled; Child, Preschool; Cleft Lip; Cleft Palate; Dipyrone; Female; Humans; | 2019 |
An exploratory study of the relationship between postoperative nausea and vomiting and postdischarge nausea and vomiting in children undergoing ambulatory surgery.
Topics: Ambulatory Surgical Procedures; Anesthesia Recovery Period; Anesthesia, General; Antiemetics; Child; | 2019 |
Is ramosetron superior to ondansetron?
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Antiemetics; Benzimidazoles; Female; Fentanyl; Hu | 2013 |
Incidence and predictors of postdischarge nausea and vomiting in a 7-day population.
Topics: Adult; Ambulatory Surgical Procedures; Anesthesia, General; Antiemetics; Female; Humans; Incidence; | 2013 |
Tramadol - the Marmite(™) drug.
Topics: Analgesics, Opioid; Antiemetics; Humans; Ondansetron; Pain, Postoperative; Tramadol | 2015 |
Tramadol and delirium.
Topics: Analgesics, Opioid; Antiemetics; Humans; Ondansetron; Pain, Postoperative; Tramadol | 2015 |
Paracetamol and unwanted 5-hydroxytryptamine interactions.
Topics: Analgesics, Opioid; Antiemetics; Humans; Ondansetron; Pain, Postoperative; Tramadol | 2015 |
Effectiveness of ondansetron as an adjunct to lidocaine intravenous regional anesthesia on tourniquet pain and postoperative pain in patients undergoing elective hand surgery: a systematic review protocol.
Topics: Adult; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Anti-Inflammatory Agents | 2015 |
Gender-Specific Differences in Low-Dose Haloperidol Response for Prevention of Postoperative Nausea and Vomiting: A Register-Based Cohort Study.
Topics: Aged; Analgesics, Opioid; Anesthesia, General; Antiemetics; Cohort Studies; Female; Haloperidol; Hum | 2016 |
[Postoperative inconveniences after breast cancer surgery].
Topics: Acetaminophen; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasms; Celecoxib; Cyc | 2008 |
[Multimodal treatment of pain and nausea in breast cancer surgery].
Topics: Adult; Aged; Aged, 80 and over; Amines; Analgesics; Antiemetics; Antitussive Agents; Breast Neoplasm | 2008 |
Discomfort, delirium, and PONV in infants and young children undergoing strabismus surgery.
Topics: Analgesics; Antiemetics; Delirium; Dexamethasone; Droperidol; Hospitals, University; Humans; Minneso | 2011 |
Post-operative nausea and vomiting following paediatric day-case tonsillectomy: audit of the Epsom protocol.
Topics: Adenoidectomy; Adolescent; Ambulatory Surgical Procedures; Analgesics; Anesthesia, General; Antiemet | 2011 |
In sickness and pain.
Topics: Analgesics; Antiemetics; Child; Dexamethasone; Humans; Ondansetron; Pain, Postoperative; Postoperati | 2002 |
Blood-borne factors possibly associated with post-operative nausea and vomiting: an explorative study in women after breast cancer surgery.
Topics: Adult; Aged; Aged, 80 and over; Anesthesia, Inhalation; Anesthetics, Inhalation; Antiemetics; Blood | 2005 |
[Narcolepsy and anesthesia].
Topics: Analgesia, Epidural; Anesthesia, Intravenous; Antiemetics; Benzhydryl Compounds; Chemical and Drug I | 2007 |
The use of ondansetron to treat pruritus associated with intrathecal morphine in two paediatric patients.
Topics: Adolescent; Analgesia; Analgesics, Opioid; Child, Preschool; Female; Humans; Injections, Intravenous | 1996 |
The impact of audit in a district general hospital on post-operative nausea and vomiting after major gynaecological surgery.
Topics: Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia Department, Hospital; Antiemetics; Att | 1998 |
Analgesic efficacy of tramadol if coadministered with ondansetron.
Topics: Analgesics, Opioid; Antiemetics; Cytochrome P-450 CYP2D6; Drug Interactions; Humans; Ondansetron; Pa | 2001 |
Postoperative pain and nausea after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesia; Cholecystectomy, Laparoscopic; Female; Humans; Male; Middle Aged; Nausea; On | 1992 |
Postoperative pain and nausea after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesia; Cholecystectomy, Laparoscopic; Female; Humans; Male; Middle Aged; Nausea; On | 1992 |
Postoperative pain and nausea after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesia; Cholecystectomy, Laparoscopic; Female; Humans; Male; Middle Aged; Nausea; On | 1992 |
Postoperative pain and nausea after laparoscopic cholecystectomy.
Topics: Adult; Aged; Analgesia; Cholecystectomy, Laparoscopic; Female; Humans; Male; Middle Aged; Nausea; On | 1992 |