Page last updated: 2024-09-22

ciramadol

Description

ciramadol: benzylamine analgesics; structure given in fourth source [Medical Subject Headings (MeSH), National Library of Medicine, extracted Dec-2023]

Cross-References

ID SourceID
PubMed CID44463
CHEMBL ID2104132
CHEBI ID135016
SCHEMBL ID26731
MeSH IDM0069621

Synonyms (28)

Synonym
ciramadol
wy-15705
D03523
63269-31-8
ciramadol (usan/inn)
wy-15,705
CHEBI:135016
3-[(r)-dimethylamino-[(1r,2r)-2-hydroxycyclohexyl]methyl]phenol
ciramadolum
9nq109ow0g ,
ciramadol [usan:inn]
phenol, 3-((dimethylamino)(2-hydroxycyclohexyl)methyl)-, (1r-(1alpha(r*),2alpha))-(-)-
(-)-(1r,2r)-2-((r)-alpha-(dimethylamino)-m-hydroxybenzyl)cyclohexanol
unii-9nq109ow0g
ciramadolum [inn-latin]
wy 15705
CHEMBL2104132
ciramadol [mart.]
(-)-(1r,2r)-2-((r)-.alpha.-(dimethylamino)-m-hydroxybenzyl)cyclohexanol
ciramadol [mi]
ciramadol [usan]
phenol, 3-((dimethylamino)(2-hydroxycyclohexyl)methyl)-, (1r-(1.alpha.(r*),2.alpha.))-(-)-
ciramadol [inn]
SCHEMBL26731
Q5121335
DTXSID601018412
HY-136653
CS-0132849

Research Excerpts

Overview

ExcerptReference
"Oral ciramadol appears to be a safe and highly effective analgesic."( Camu, F, 1981)
"Ciramadol is a new opioid agonist-antagonist analgesic with low potential for dependency. "( McAdams, J; Stambaugh, JE, 1987)

Drug Classes (1)

ClassDescription
cyclohexanolsAn alcohol in which one or more hydroxy groups are attached to a cyclohexane skeleton.
[compound class information is derived from Chemical Entities of Biological Interest (ChEBI), Hastings J, Owen G, Dekker A, Ennis M, Kale N, Muthukrishnan V, Turner S, Swainston N, Mendes P, Steinbeck C. (2016). ChEBI in 2016: Improved services and an expanding collection of metabolites. Nucleic Acids Res]

Research

Studies (33)

TimeframeStudies, This Drug (%)All Drugs %
pre-199033 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Study Types

Publication TypeThis drug (%)All Drugs (%)
Trials18 (47.37%)5.53%
Reviews1 (2.63%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other19 (50.00%)84.16%
[information is prepared from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Research Highlights

Safety/Toxicity (1)

ArticleYear
Comparison of the analgesic efficacy and safety oral ciramadol, codeine, and placebo in patients with chronic cancer pain.
Journal of clinical pharmacology, Volume: 27, Issue: 2
1987
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Pharmacokinetics (1)

ArticleYear
Preliminary pharmacokinetics of intravenous ciramadol in humans.
International journal of clinical pharmacology, therapy, and toxicology, Volume: 22, Issue: 6
1984
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Bioavailability (2)

ArticleYear
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]

Dosage (5)

ArticleYear
Comparative evaluation of ciramadol (WY-15.705), morphine and placebo for treatment of postoperative pain.
Acta anaesthesiologica Belgica, Volume: 36, Issue: 2
1985
Oral ciramadol in the treatment of postoperative pain.
Clinical pharmacology and therapeutics, Volume: 38, Issue: 2
1985
Hemodynamic and respiratory effects of dezocine, ciramadol, and morphine.
Clinical pharmacology and therapeutics, Volume: 38, Issue: 1
1985
The metabolic disposition of 14C-ciramadol in humans.
Xenobiotica; the fate of foreign compounds in biological systems, Volume: 16, Issue: 4
1986
[information is derived through text-mining from research data collected from National Library of Medicine (NLM), extracted Dec-2023]