diflunisal has been researched along with Acute Post-operative Pain in 42 studies
Diflunisal: A salicylate derivative and anti-inflammatory analgesic with actions and side effects similar to those of ASPIRIN.
diflunisal : An organofluorine compound comprising salicylic acid having a 2,4-difluorophenyl group at the 5-position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Diflunisal is a long-acting non-steroidal anti-inflammatory drug (NSAID) most commonly used to treat acute postoperative pain or chronic joint pain from osteoarthritis and rheumatoid arthritis." | 6.46 | Single dose oral diflunisal for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA; Wasey, JO, 2010) |
| "Diflunisal was given for postoperative pain relief." | 2.67 | Does midazolam sedation in oral surgery affect the potency or duration of diflunisal analgesia? ( Rodrigo, MR; Rosenquist, JB, 1990) |
| " After one-visit nonsurgical endodontic therapy, 100 patients with asymptomatic teeth having either vital-inflamed pulp, pulpal necrosis, or pulpal necrosis with periapical radiolucent lesion were randomly given either prophylactic diflunisal (two tablets immediately at the conclusion of the visit, then four tablets to be taken in the schedule of one every 8 to 12 hours for pain if needed) or on-demand diflunisal (same dosage schedule; pills to be taken only if needed)." | 2.67 | Comparison of prophylactic and on-demand diflunisal for pain management of patients having one-visit endodontic therapy. ( Esposito, JV; Furst, ML; Morse, DR, 1990) |
| "Treatment with diflunisal 30 minutes after completion of surgery proved to be just as effective in suppressing postsurgical pain as presurgical administration." | 2.66 | Comparison of preoperative and postoperative diflunisal for suppression of postoperative pain. ( Martin, RP; Mosley, RO; Sisk, AL, 1989) |
| "Diflunisal was found to be superior in relieving pain in the early postoperative period, the associated frequency of adverse clinical experiences was lower and the final evaluation of analgesic efficacy by both the patients and the investigators, was in its favour." | 2.66 | Analgesic efficacy and tolerability of diflunisal in oral surgery. ( Kinnunen, J; Pernu, H, 1987) |
| "Diflunisal plus codeine was better than placebo from 1 1/2 to 8 hours (p less than 0." | 2.66 | A double-blind study of diflunisal and codeine compared with codeine or diflunisal alone in postoperative pain. ( Berman, R; Jain, A; McMahon, FG; Ryan, JR; Smith, G, 1988) |
| "Diflunisal was found to be generally effective and well-tolerated, and superior to aspirin with codeine in the management of pain from endodontic treatment." | 2.66 | Comparison of diflunisal and an aspirin-codeine combination in the management of patients having one-visit endodontic therapy. ( Bolanos, OR; Esposito, JV; Furst, ML; Koren, LZ; Morse, DR; Yesilsoy, C, 1987) |
| " Despite great differences in dosage and half-life, the active test substances must be regarded as equipment." | 2.65 | [A controlled clinical single-dose comparative study of suprofen and diflunisal]. ( Arabin, G; Honig, WJ; van Ochten, J, 1983) |
| "Diflunisal is a long-acting non-steroidal anti-inflammatory drug (NSAID) most commonly used to treat acute postoperative pain or chronic joint pain from osteoarthritis and rheumatoid arthritis." | 2.46 | Single dose oral diflunisal for acute postoperative pain in adults. ( Derry, S; McQuay, HJ; Moore, RA; Wasey, JO, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 29 (69.05) | 18.7374 |
| 1990's | 7 (16.67) | 18.2507 |
| 2000's | 4 (9.52) | 29.6817 |
| 2010's | 2 (4.76) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Davey, J | 1 |
| Wasey, JO | 1 |
| Derry, S | 1 |
| Moore, RA | 1 |
| McQuay, HJ | 1 |
| Comfort, MB | 2 |
| Tse, AS | 1 |
| Tsang, AC | 1 |
| McGrath, C | 1 |
| Pektas, ZO | 1 |
| Sener, M | 2 |
| Bayram, B | 1 |
| Eroglu, T | 1 |
| Bozdogan, N | 1 |
| Donmez, A | 2 |
| Arslan, G | 2 |
| Uckan, S | 1 |
| Yilmazer, C | 1 |
| Yilmaz, I | 1 |
| Erkan, AN | 1 |
| Cagici, CA | 1 |
| Ozluoglu, LN | 1 |
| Leilich, G | 1 |
| Cooper, SA | 1 |
| Honig, WJ | 2 |
| Arabin, G | 1 |
| van Ochten, J | 1 |
| Hugly, C | 1 |
| Ackermann, K | 1 |
| Irvine, GH | 1 |
| Lutterloch, MJ | 1 |
| Bowerman, JE | 1 |
| White, P | 1 |
| Strunin, L | 1 |
| Sitzmann, F | 1 |
| Dumbach, J | 1 |
| Fonseca, JB | 1 |
| Gregori, C | 1 |
| de Moura Campos, FE | 1 |
| Piratininga, JL | 1 |
| da Graça Naclerio Homem, M | 1 |
| de Souza Lobo, NB | 1 |
| Antonini, R | 1 |
| Ihalainen, U | 1 |
| Rissanen, H | 1 |
| Oikarinen, VJ | 1 |
| Lawton, GM | 1 |
| Chapman, PJ | 2 |
| Rodrigo, MR | 3 |
| Lee, KM | 1 |
| Selçuk, E | 1 |
| Gomel, M | 1 |
| Bellibas, SE | 1 |
| Köse, T | 1 |
| Tuğlular, I | 1 |
| Sençift, K | 1 |
| Kir, S | 1 |
| Tuncer, M | 1 |
| Alaçam, T | 1 |
| Tinaz, AC | 1 |
| Nishi, M | 1 |
| Nagayama, K | 1 |
| Oka, I | 1 |
| Minutello, JS | 2 |
| Hewell, DH | 1 |
| Thrash, WJ | 2 |
| Terezhalmy, GT | 2 |
| Rosenquist, JB | 3 |
| Morse, DR | 2 |
| Esposito, JV | 2 |
| Furst, ML | 2 |
| Rodrigo, C | 1 |
| Chau, M | 1 |
| Rosenquist, J | 1 |
| Cumbo, V | 1 |
| Messina, P | 1 |
| Sisk, AL | 1 |
| Mosley, RO | 1 |
| Martin, RP | 1 |
| Clark, MS | 1 |
| Lindenmuth, JE | 1 |
| Silverstone, LM | 1 |
| Fryer, GE | 1 |
| Cheung, LK | 1 |
| Hill, CM | 1 |
| Carroll, MJ | 1 |
| Giles, AD | 1 |
| Pickvance, N | 1 |
| Kinnunen, J | 1 |
| Pernu, H | 1 |
| Newell, DH | 1 |
| Bella, G | 1 |
| Russo, S | 1 |
| Messina, G | 1 |
| Jain, A | 1 |
| McMahon, FG | 1 |
| Ryan, JR | 1 |
| Smith, G | 1 |
| Berman, R | 1 |
| Nystrom, E | 1 |
| Vallania, G | 1 |
| Capuzzi, P | 1 |
| Baroni, C | 1 |
| Cavalli, A | 1 |
| Koren, LZ | 1 |
| Bolanos, OR | 1 |
| Yesilsoy, C | 1 |
| Fulkerson, JP | 1 |
| Folcik, MA | 1 |
| Seymour, RA | 1 |
4 reviews available for diflunisal and Acute Post-operative Pain
| Article | Year |
|---|---|
Single dose oral diflunisal for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; Hum | 2010 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials | 1983 |
Non-steroidal anti-inflammatory drugs (NSAID'S) as analgesics in dentistry - a review.
Topics: Analgesics; Anti-Inflammatory Agents; Aspirin; Dental Care; Diflunisal; Humans; Ibuprofen; Indometha | 1983 |
Diflunisal--a long-acting non-steroidal anti-inflammatory drug. A review of its pharmacology and effectiveness in management of postoperative dental pain.
Topics: Diflunisal; Drug Interactions; Humans; Molar, Third; Pain, Postoperative; Time Factors; Tooth Extrac | 1993 |
27 trials available for diflunisal and Acute Post-operative Pain
| Article | Year |
|---|---|
A study of the comparative efficacy of three common analgesics in the control of pain after third molar surgery under local anaesthesia.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthesia, Dental; Anesthe | 2002 |
A comparison of pre-emptive analgesic efficacy of diflunisal and lornoxicam for postoperative pain management: a prospective, randomized, single-blind, crossover study.
Topics: Adolescent; Adult; Anti-Inflammatory Agents; Cross-Over Studies; Diflunisal; Drug Combinations; Faci | 2007 |
Pre-emptive analgesia for removal of nasal packing: A double-blind placebo controlled study.
Topics: Administration, Oral; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diflunisal; | 2007 |
[Clinical test of an analgesic].
Topics: Adolescent; Adult; Clinical Trials as Topic; Diflunisal; Female; Humans; Male; Pain, Postoperative; | 1983 |
New peripherally-acting oral analgesic agents.
Topics: Administration, Oral; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Clinical Trials | 1983 |
[A controlled clinical single-dose comparative study of suprofen and diflunisal].
Topics: Adolescent; Adult; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; | 1983 |
Clinical comparison of the analgesic efficacy of suprofen, diflunisal and placebo in the treatment of pain after meniscectomy.
Topics: Adolescent; Adult; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Knee J | 1983 |
[Analgesic and anti-inflammatory action of Diflunisal in dental surgery. Comparative clinical study in combination with Trypsin/chymotrypsin/P-amino-phenol].
Topics: Adolescent; Adult; Aminophenols; Child; Chymotrypsin; Clinical Trials as Topic; Diflunisal; Drug Com | 1980 |
The efficacy and tolerability of diflunisal and ASA in the relief of postoperative pain in oral surgery.
Topics: Adolescent; Adult; Aspirin; Clinical Trials as Topic; Diflunisal; Female; Humans; Male; Middle Aged; | 1980 |
Pre-operative diflunisal for pain relief following third molar surgery under general anaesthesia.
Topics: Adolescent; Adult; Anesthesia, Dental; Anesthesia, General; Diflunisal; Double-Blind Method; Female; | 1993 |
Comparison of the analgesic effects of diflunisal and paracetamol in the treatment of postoperative dental pain.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 1996 |
Clinical effects of diflunisal and paracetamol in impacted mandibular third molar surgery.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; | 1997 |
Interappointment emergencies in teeth with necrotic pulps.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Child; Dental Fistula; Dental Pulp Necro | 2002 |
Evaluation of postoperative diflunisal for periodontal surgery pain.
Topics: Adult; Diflunisal; Double-Blind Method; Humans; Middle Aged; Pain Measurement; Pain, Postoperative; | 1991 |
Does midazolam sedation in oral surgery affect the potency or duration of diflunisal analgesia?
Topics: Adolescent; Adult; Anesthesia, Local; Conscious Sedation; Diflunisal; Drug Interactions; Female; Hum | 1990 |
Comparison of prophylactic and on-demand diflunisal for pain management of patients having one-visit endodontic therapy.
Topics: Adolescent; Adult; Aged; Dental Pulp Necrosis; Diflunisal; Drug Administration Schedule; Female; Hum | 1990 |
A comparison of paracetamol and diflunisal for pain control following 3rd molar surgery.
Topics: Acetaminophen; Adult; Diflunisal; Double-Blind Method; Female; Humans; Male; Molar, Third; Pain, Pos | 1989 |
Comparison of preoperative and postoperative diflunisal for suppression of postoperative pain.
Topics: Adolescent; Adult; Diflunisal; Drug Administration Schedule; Female; Humans; Male; Molar, Third; Pai | 1989 |
Postoperative pain control for outpatient oral surgery.
Topics: Acetaminophen; Administration, Oral; Adolescent; Adult; Clinical Trials as Topic; Codeine; Diflunisa | 1987 |
Paracetamol and diflunisal for pain relief following third molar surgery in Hong Kong Chinese.
Topics: Acetaminophen; Adult; China; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Hong | 1987 |
Ibuprofen given pre- and post-operatively for the relief of pain.
Topics: Adolescent; Adult; Aged; Clinical Trials as Topic; Codeine; Diflunisal; Double-Blind Method; Drug Co | 1987 |
Analgesic efficacy and tolerability of diflunisal in oral surgery.
Topics: Adult; Aminopyrine; Barbital; Barbiturates; Clinical Trials as Topic; Diflunisal; Double-Blind Metho | 1987 |
Evaluation of preoperative diflunisal for postoperative pain following periodontal surgery.
Topics: Adolescent; Adult; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; Middle Aged; P | 1988 |
[Clinical trial of a new non-steroidal analgesic (diflunisal) in oral surgery].
Topics: Adult; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Female; Humans; Male; Mid | 1987 |
A double-blind study of diflunisal and codeine compared with codeine or diflunisal alone in postoperative pain.
Topics: Adult; Codeine; Diflunisal; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Male; Pa | 1988 |
[Use of diflunisal in postoperative pain of the oral cavity].
Topics: Adolescent; Adult; Aged; Aspirin; Clinical Trials as Topic; Diflunisal; Double-Blind Method; Humans; | 1986 |
Comparison of diflunisal and an aspirin-codeine combination in the management of patients having one-visit endodontic therapy.
Topics: Adolescent; Adult; Aged; Aspirin; Codeine; Diflunisal; Drug Combinations; Female; Humans; Male; Midd | 1987 |
12 other studies available for diflunisal and Acute Post-operative Pain
| Article | Year |
|---|---|
The advantages and limitations of the analgesics available for control of postoperative pain after a dental procedure.
Topics: Acetaminophen; Analgesics; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Aspiri | 2013 |
[Evaluation of the efficacy and tolerance of diflunisal in treatment of pain in dentistry].
Topics: Adolescent; Adult; Aged; Child; Diflunisal; Humans; Middle Aged; Mouth; Pain, Postoperative; Periapi | 1983 |
[Diflunisal in dental surgery].
Topics: Adolescent; Adult; Diflunisal; Female; Humans; Male; Middle Aged; Pain, Postoperative; Placebos; Sal | 1983 |
Comparison of diflunisal and paracetamol in the management of pain following wisdom teeth removal.
Topics: Acetaminophen; Adult; Aged; Diflunisal; Double-Blind Method; Female; Humans; Male; Middle Aged; Mola | 1982 |
Post-anaesthetic dental extraction analgesia: a comparison of paracetamol, codeine, caffeine (Solpadeine) and diflunisal (Dolobid).
Topics: Acetaminophen; Adolescent; Adult; Aged; Anesthesia, Dental; Anesthesia, General; Caffeine; Codeine; | 1982 |
[Diflunisal in treatment of pain after jaw surgery].
Topics: Adolescent; Adult; Diflunisal; Humans; Middle Aged; Orthognathic Surgical Procedures; Pain, Postoper | 1982 |
[Clinical effects of MK-647 (diflunisal) for postsurgical pain of the oral area].
Topics: Adult; Aged; Diflunisal; Female; Humans; Male; Mandibular Neoplasms; Maxillary Neoplasms; Middle Age | 1979 |
[Analgesic efficiency and tolerability of Diflunisal].
Topics: Adult; Diflunisal; Female; Humans; Male; Middle Aged; Mouth Diseases; Pain, Postoperative | 1989 |
A double-blind single-dose evaluation of the relative analgesic efficacy and safety of carprofen in the treatment of postoperative pain after oral surgery.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Carbazoles; Diflunisal; Double- | 1989 |
Long-acting analgesic or long-acting local anesthetic in controlling immediate postoperative pain after lower third molar surgery.
Topics: Adult; Bupivacaine; Diflunisal; Double-Blind Method; Drug Therapy, Combination; Female; Humans; Lido | 1987 |
Analgesia following arthroscopic surgery: comparison of diflunisal and acetaminophen with codeine.
Topics: Acetaminophen; Adolescent; Adult; Analgesia; Codeine; Diflunisal; Drug Combinations; Female; Humans; | 1986 |
Prescribing analgesics.
Topics: Acetaminophen; Aged; Analgesics; Anticoagulants; Aspirin; Child; Codeine; Diflunisal; Drug Hypersens | 1985 |