phentolamine has been researched along with Acute Post-operative Pain in 4 studies
Phentolamine: A nonselective alpha-adrenergic antagonist. It is used in the treatment of hypertension and hypertensive emergencies, pheochromocytoma, vasospasm of RAYNAUD DISEASE and frostbite, clonidine withdrawal syndrome, impotence, and peripheral vascular disease.
phentolamine : A substituted aniline that is 3-aminophenol in which the hydrogens of the amino group are replaced by 4-methylphenyl and 4,5-dihydro-1H-imidazol-2-ylmethyl groups respectively. An alpha-adrenergic antagonist, it is used for the treatment of hypertension.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Phentolamine Mesylate (PM) is a pharmacological agent capable of reducing the duration of soft tissue anesthesia following dental treatments." | 2.87 | Reversing the effects of 2% Lidocaine: A randomized controlled clinical trial. ( Brillant, MS; Flood, B; Michaud, PL, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (75.00) | 29.6817 |
| 2010's | 1 (25.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Michaud, PL | 1 |
| Flood, B | 1 |
| Brillant, MS | 1 |
| Tavares, M | 1 |
| Goodson, JM | 1 |
| Studen-Pavlovich, D | 1 |
| Yagiela, JA | 1 |
| Navalta, LA | 1 |
| Rogy, S | 1 |
| Rutherford, B | 1 |
| Gordon, S | 1 |
| Papas, AS | 1 |
| Lin, EE | 1 |
| Horasek, S | 1 |
| Agarwal, S | 1 |
| Wu, CL | 1 |
| Raja, SN | 1 |
| Hudcova, J | 1 |
| Schumann, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Reversing the Effects of 2% Lidocaine: A Randomized Controlled Trial[NCT02861378] | 38 participants (Actual) | Interventional | 2015-10-31 | Completed | |||
| Phentolamine Mesylate as a Reversal of Local Anesthesics[NCT03740386] | 90 participants (Actual) | Interventional | 2016-01-01 | Completed | |||
| A Phase 4, Multicenter, Randomized, Double-Blinded, Controlled Study of OraVerse® for Safety and Efficacy in Pediatric Dental Patients Undergoing Mandibular and Maxillary Procedures[NCT01474382] | Phase 4 | 150 participants (Actual) | Interventional | 2012-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 trials available for phentolamine and Acute Post-operative Pain
| Article | Year |
|---|---|
Reversing the effects of 2% Lidocaine: A randomized controlled clinical trial.
Topics: Adult; Anesthesia, Dental; Anesthesia, Local; Anesthetics, Local; Epinephrine; Humans; Injections; L | 2018 |
Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients.
Topics: Adrenergic alpha-Antagonists; Analgesics; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetic | 2008 |
Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients.
Topics: Adrenergic alpha-Antagonists; Analgesics; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetic | 2008 |
Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients.
Topics: Adrenergic alpha-Antagonists; Analgesics; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetic | 2008 |
Reversal of soft-tissue local anesthesia with phentolamine mesylate in pediatric patients.
Topics: Adrenergic alpha-Antagonists; Analgesics; Anesthesia Recovery Period; Anesthesia, Dental; Anesthetic | 2008 |
Local administration of norepinephrine in the stump evokes dose-dependent pain in amputees.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Amputation Stumps; Area Under Curve; Dose-Response Relati | 2006 |
1 other study available for phentolamine and Acute Post-operative Pain
| Article | Year |
|---|---|
Undiagnosed catecholamine-secreting paraganglioma and coexisting carcinoid in a patient with MH susceptibility: an unusual anesthetic challenge.
Topics: Adrenergic alpha-Agonists; Adult; Anesthesia, Epidural; Anesthesia, General; Anesthetics, Intravenou | 2007 |