nitroglycerin has been researched along with Acute Post-operative Pain in 31 studies
Nitroglycerin: A volatile vasodilator which relieves ANGINA PECTORIS by stimulating GUANYLATE CYCLASE and lowering cytosolic calcium. It is also sometimes used for TOCOLYSIS and explosives.
nitroglycerol : A nitrate ester that is glycerol in which nitro group(s) replace the hydrogen(s) attached to one or more of the hydroxy groups.
nitroglycerin : A nitroglycerol that is glycerol in which the hydrogen atoms of all three hydroxy groups are replaced by nitro groups. It acts as a prodrug, releasing nitric oxide to open blood vessels and so alleviate heart pain.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a prospective, double-blind, randomized trial, we tested the effect of intravenous nitroglycerin on the incidence of angina and minor myocardial necrosis (MMN), as detected by cardiac troponin I increase, after elective coronary stenting." | 9.09 | A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. ( Bertel, O; Kurz, DJ; Naegeli, B, 2000) |
| "Nitroglycerin (NTG) has the potential to reduce myocardial ischemia during percutaneous transluminal coronary angioplasty (PTCA)." | 6.67 | Buccal nitroglycerin decreases ischemic pain during coronary angioplasty: a double-blind, randomized, placebo-controlled study. ( Ekström, L; Emanuelsson, H; Johansson, SR, 1990) |
| " In a prospective, double-blind, randomized trial, we tested the effect of intravenous nitroglycerin on the incidence of angina and minor myocardial necrosis (MMN), as detected by cardiac troponin I increase, after elective coronary stenting." | 5.09 | A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting. ( Bertel, O; Kurz, DJ; Naegeli, B, 2000) |
| "Early postoperative pain after 30 and 60 minutes and the requirement for meperidine were not meaningfully different between the 2 groups." | 2.79 | Evaluation of the advantageous anesthetic properties of dexmedetomidine used as hypotensive agent compared with nitroglycerin in orthognathic surgery. ( Apipan, B; Rummasak, D, 2014) |
| "Nitroglycerine (NTG) has analgesic properties." | 2.76 | The analgesic effect of three different doses of nitroglycerine when added to lidocaine for intravenous regional anesthesia in trauma patients. ( Fatemy, A; Honarmand, A; Safavi, M, 2011) |
| "Fentanyl is a short-acting synthetic opioid with spinal analgesic properties and dose-dependent side-effects." | 2.75 | The effect of transdermal nitroglycerine on intrathecal fentanyl with bupivacaine for postoperative analgesia following gynaecological surgery. ( Ahmed, F; Chawla, V; Garg, A; Khandelwal, M; Verma, AP, 2010) |
| "Overall analysis of postoperative pain at rest showed a significant reduction in the botulinum toxin group vs." | 2.72 | Botulinum toxin vs. topical glyceryl trinitrate ointment for pain control in patients undergoing hemorrhoidectomy: a randomized trial. ( Almasio, PL; Arcara, M; Calogero, F; Di Vita, G; Fede, C; Gaetano, DV; Luigi, AP; Matteo, A; Patti, R; Pietro, R; Romano, P; Sammartano, S; Sergio, S, 2006) |
| "Nitroglycerin (NTG) has been found efficacious in acute pain, but has not been tested for chronic pain with neuropathic characteristics." | 2.71 | Efficacy of transdermal nitroglycerin combined with etodolac for the treatment of chronic post-thoracotomy pain: an open-label prospective clinical trial. ( Eidelman, LA; Glantz, L; Godovic, G; Kramer, M; Lekar, M, 2004) |
| "Nitroglycerin (NTG) has the potential to reduce myocardial ischemia during percutaneous transluminal coronary angioplasty (PTCA)." | 2.67 | Buccal nitroglycerin decreases ischemic pain during coronary angioplasty: a double-blind, randomized, placebo-controlled study. ( Ekström, L; Emanuelsson, H; Johansson, SR, 1990) |
| "Hemorrhoidectomy is associated with postoperative pain and prolonged wound healing." | 2.53 | Effect of Glyceryl Trinitrate Ointment on Pain Control After Hemorrhoidectomy: A Meta-analysis of Randomized Controlled Trials. ( Kiu, KT; Lin, CC; Liu, JW; Tam, KW; Wang, CY, 2016) |
| "Current postoperative pain therapy revolves around the use of wound infiltration and systemic administration of opioids, nonsteroidal anti-inflammatory drugs and paracetamol." | 2.46 | Topical application of analgesics: a clinical option in day case anaesthesia? ( McCleane, G, 2010) |
| "The side effect of headache has often been an associated problem." | 2.46 | Meta-analysis of the use of glyceryl trinitrate ointment after haemorrhoidectomy as an analgesic and in promoting wound healing. ( Andreani, SM; Light, D; Patel, B; Ratnasingham, K; Uzzaman, M, 2010) |
| "Esmolol was used in 25% of patients to reduce motion of the left ventricle (LV) during the left internal mammary artery (LIMA)-LAD anastomosis, but was used less often as the surgeons adapted to the use of a retractor that stabilized the ventricular wall adjacent to the site of the LIMA-LAD anastomosis." | 1.30 | Minimally invasive direct coronary artery bypass: anesthetic, monitoring, and pain control considerations. ( Gravlee, GP; Heres, EK; Magovern, JA; Malkowski, MJ; Marquez, J, 1998) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (12.90) | 18.2507 |
| 2000's | 14 (45.16) | 29.6817 |
| 2010's | 11 (35.48) | 24.3611 |
| 2020's | 2 (6.45) | 2.80 |
| Authors | Studies |
|---|---|
| Jin, J | 1 |
| Unasa, H | 1 |
| Bahl, P | 1 |
| Mauiliu-Wallis, M | 1 |
| Svirskis, D | 1 |
| Hill, A | 1 |
| Yang, Y | 1 |
| Feng, K | 1 |
| Lei, Y | 1 |
| Qiu, L | 1 |
| Liu, C | 1 |
| Li, G | 1 |
| Mari, FS | 1 |
| Nigri, G | 1 |
| Dall'Oglio, A | 1 |
| Cosenza, UM | 1 |
| Milillo, A | 1 |
| Terrenato, I | 1 |
| Pancaldi, A | 1 |
| Brescia, A | 1 |
| Khan, KI | 1 |
| Waqas, A | 1 |
| Akmal, M | 1 |
| Mahmood, S | 1 |
| Iqbal, A | 1 |
| Cakmak, BM | 1 |
| Cakmak, G | 1 |
| Akpek, E | 1 |
| Arslan, G | 1 |
| Sahin, MS | 1 |
| Rummasak, D | 1 |
| Apipan, B | 1 |
| Liu, JW | 1 |
| Lin, CC | 1 |
| Kiu, KT | 1 |
| Wang, CY | 1 |
| Tam, KW | 1 |
| Feltracco, P | 1 |
| Brezzi, ML | 1 |
| Barbieri, S | 1 |
| Serra, E | 1 |
| Milevoj, M | 1 |
| Ori, C | 1 |
| Karanlik, H | 1 |
| Akturk, R | 1 |
| Camlica, H | 1 |
| Asoglu, O | 1 |
| Gentile, A | 1 |
| Tran-Van, D | 1 |
| Dardare, E | 1 |
| Fritsch, N | 1 |
| Benois, A | 1 |
| Fontaine, B | 1 |
| McCleane, G | 1 |
| Garg, A | 1 |
| Ahmed, F | 1 |
| Khandelwal, M | 1 |
| Chawla, V | 1 |
| Verma, AP | 1 |
| Ratnasingham, K | 1 |
| Uzzaman, M | 1 |
| Andreani, SM | 1 |
| Light, D | 1 |
| Patel, B | 1 |
| Siddiqui, MR | 1 |
| Daulatzai, N | 1 |
| Honarmand, A | 1 |
| Safavi, M | 1 |
| Fatemy, A | 1 |
| Franceschilli, L | 1 |
| D'Ugo, S | 1 |
| de Luca, E | 1 |
| Cadeddu, F | 1 |
| Milito, G | 1 |
| di Lorenzo, N | 1 |
| Gaspari, AL | 1 |
| Sileri, P | 1 |
| Elton, C | 1 |
| Sen, P | 1 |
| Montgomery, AC | 1 |
| Hwang, DY | 1 |
| Yoon, SG | 1 |
| Kim, HS | 1 |
| Lee, JK | 1 |
| Kim, KY | 1 |
| Glantz, L | 1 |
| Godovic, G | 1 |
| Lekar, M | 1 |
| Kramer, M | 1 |
| Eidelman, LA | 1 |
| Sen, S | 1 |
| Ugur, B | 1 |
| Aydin, ON | 1 |
| Ogurlu, M | 1 |
| Gursoy, F | 1 |
| Savk, O | 1 |
| Ball, AM | 1 |
| Smith, KM | 1 |
| Patti, R | 1 |
| Almasio, PL | 1 |
| Luigi, AP | 1 |
| Arcara, M | 1 |
| Matteo, A | 1 |
| Sammartano, S | 1 |
| Sergio, S | 1 |
| Romano, P | 1 |
| Pietro, R | 1 |
| Fede, C | 1 |
| Calogero, F | 1 |
| Di Vita, G | 1 |
| Gaetano, DV | 1 |
| Tan, KY | 1 |
| Sng, KK | 1 |
| Tay, KH | 1 |
| Lai, JH | 1 |
| Eu, KW | 1 |
| Davies, MJ | 1 |
| Silbert, BS | 1 |
| Mooney, PJ | 1 |
| Dysart, RH | 1 |
| Meads, AC | 1 |
| Heres, EK | 1 |
| Marquez, J | 1 |
| Malkowski, MJ | 1 |
| Magovern, JA | 1 |
| Gravlee, GP | 1 |
| Kurz, DJ | 1 |
| Naegeli, B | 1 |
| Bertel, O | 1 |
| Lauretti, GR | 2 |
| Oliveira, AP | 2 |
| Julião, MC | 1 |
| Reis, MP | 1 |
| Pereira, NL | 1 |
| Wasvary, HJ | 1 |
| Hain, J | 1 |
| Mosed-Vogel, M | 1 |
| Bendick, P | 1 |
| Barkel, DC | 1 |
| Klein, SN | 1 |
| Rodrigues, AM | 1 |
| Paccola, CA | 1 |
| Ross, A | 1 |
| Johansson, SR | 1 |
| Ekström, L | 1 |
| Emanuelsson, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Topical Application of GTN 0.4% in the Treatment of Anismus Following Stapled Haemorrhoidopexy[NCT01279551] | Phase 2/Phase 3 | 40 participants (Actual) | Interventional | 2004-01-31 | Completed | ||
| Effects of Addition of Systemic Tramadol or Adjunct Tramadol to Lidocaine Used for Intravenous Regional Anesthesia in Patients Undergoing Hand Surgery[NCT02658721] | Phase 3 | 60 participants (Actual) | Interventional | 2013-01-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
7 reviews available for nitroglycerin and Acute Post-operative Pain
| Article | Year |
|---|---|
Can Targeting Sphincter Spasm Reduce Post-Haemorrhoidectomy Pain? A Systematic Review and Meta-Analysis.
Topics: Botulinum Toxins; Diltiazem; Hemorrhoidectomy; Humans; Nitroglycerin; Pain, Postoperative; Spasm | 2023 |
Comparing the efficacy and safety of different analgesic strategies after open hemorrhoidectomy: a systematic review and network meta-analysis.
Topics: Analgesics; Diltiazem; Hemorrhoidectomy; Humans; Network Meta-Analysis; Nitroglycerin; Ointments; Pa | 2023 |
Effect of Glyceryl Trinitrate Ointment on Pain Control After Hemorrhoidectomy: A Meta-analysis of Randomized Controlled Trials.
Topics: Analgesics, Non-Narcotic; Headache; Hemorrhoidectomy; Hemorrhoids; Humans; Nitroglycerin; Ointments; | 2016 |
[Management of transdermal therapeutics in perioperative care].
Topics: Administration, Cutaneous; Analgesics; Anesthetics; Cardiovascular System; Contraindications; Diffus | 2009 |
Topical application of analgesics: a clinical option in day case anaesthesia?
Topics: Administration, Topical; Ambulatory Surgical Procedures; Analgesia; Analgesics; Analgesics, Opioid; | 2010 |
Meta-analysis of the use of glyceryl trinitrate ointment after haemorrhoidectomy as an analgesic and in promoting wound healing.
Topics: Analgesics; Headache; Hemorrhoids; Humans; Nitroglycerin; Ointments; Pain Measurement; Pain, Postope | 2010 |
Postoperative pain management: can transdermal patches help?
Topics: Administration, Cutaneous; Analgesics; Anesthetics, Local; Antiemetics; Clonidine; Fentanyl; Humans; | 2006 |
20 trials available for nitroglycerin and Acute Post-operative Pain
| Article | Year |
|---|---|
Topical glyceryl trinitrate ointment for pain related to anal hypertonia after stapled hemorrhoidopexy: a randomized controlled trial.
Topics: Administration, Topical; Adult; Anal Canal; Female; Hemorrhoids; Humans; Lidocaine; Male; Middle Age | 2013 |
Efficacy of combination of 0.2% GTN and lignocaine ointments in wound healing and pain relief after Milligan Morgan hemorrhoidectomy--a comparison with lignocaine and 0.2% GTN ointments separately.
Topics: Adult; Anesthetics, Local; Double-Blind Method; Female; Hemorrhoidectomy; Hemorrhoids; Humans; Lidoc | 2014 |
Peri- and postanalgesic properties of lidokain, lornoxicam, and nitroglycerine combination at intravenous regional anesthesia.
Topics: Administration, Intravenous; Adolescent; Adult; Analgesics; Anesthesia, Conduction; Anesthesia, Intr | 2014 |
Evaluation of the advantageous anesthetic properties of dexmedetomidine used as hypotensive agent compared with nitroglycerin in orthognathic surgery.
Topics: Adult; Antihypertensive Agents; Dexmedetomidine; Female; Humans; Hypnotics and Sedatives; Male; Nitr | 2014 |
The effect of glyceryl trinitrate ointment on posthemorrhoidectomy pain and wound healing: results of a randomized, double-blind, placebo-controlled study.
Topics: Administration, Topical; Adult; Analgesics; Double-Blind Method; Female; Hemorrhoids; Humans; Male; | 2009 |
The effect of transdermal nitroglycerine on intrathecal fentanyl with bupivacaine for postoperative analgesia following gynaecological surgery.
Topics: Administration, Cutaneous; Adult; Anesthetics, Local; Bupivacaine; Cyclic GMP; Double-Blind Method; | 2010 |
The analgesic effect of three different doses of nitroglycerine when added to lidocaine for intravenous regional anesthesia in trauma patients.
Topics: Adolescent; Adult; Aged; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Local; Drug A | 2011 |
Role of 0.4% glyceryl trinitrate ointment after haemorrhoidectomy: results of a prospective randomised study.
Topics: Adult; Aged; Demography; Female; Hemorrhoidectomy; Hemorrhoids; Humans; Male; Middle Aged; Nitroglyc | 2013 |
Initial study to assess the effects of topical glyceryl trinitrate for pain after haemorrhoidectomy.
Topics: Administration, Topical; Aged; Double-Blind Method; Drug Administration Schedule; Female; Follow-Up | 2001 |
Effect of 0.2 percent glyceryl trinitrate ointment on wound healing after a hemorrhoidectomy: results of a randomized, prospective, double-blind, placebo-controlled trial.
Topics: Administration, Topical; Adult; Double-Blind Method; Female; Hemorrhoids; Humans; Male; Middle Aged; | 2003 |
Efficacy of transdermal nitroglycerin combined with etodolac for the treatment of chronic post-thoracotomy pain: an open-label prospective clinical trial.
Topics: Administration, Cutaneous; Aged; Anti-Inflammatory Agents, Non-Steroidal; Drug Therapy, Combination; | 2004 |
The analgesic effect of nitroglycerin added to lidocaine on intravenous regional anesthesia.
Topics: Adult; Aged; Anesthesia, Conduction; Anesthesia, Intravenous; Anesthetics, Combined; Double-Blind Me | 2006 |
Botulinum toxin vs. topical glyceryl trinitrate ointment for pain control in patients undergoing hemorrhoidectomy: a randomized trial.
Topics: Adult; Botulinum Toxins, Type A; Defecation; Female; Hemorrhoids; Humans; Injections; Male; Manometr | 2006 |
Randomized clinical trial of 0.2 per cent glyceryl trinitrate ointment for wound healing and pain reduction after open diathermy haemorrhoidectomy.
Topics: Adult; Analgesics; Diathermy; Double-Blind Method; Female; Hemorrhoids; Humans; Male; Middle Aged; N | 2006 |
Combined epidural and general anaesthesia versus general anaesthesia for abdominal aortic surgery: a prospective randomised trial.
Topics: Aged; Analgesia; Analgesia, Epidural; Anesthesia, Epidural; Anesthesia, General; Aorta, Abdominal; A | 1993 |
A double-blind, randomized study of the effect of immediate intravenous nitroglycerin on the incidence of postprocedural chest pain and minor myocardial necrosis after elective coronary stenting.
Topics: Angina Pectoris; Angioplasty, Balloon, Coronary; Biomarkers; Coronary Angiography; Coronary Disease; | 2000 |
Transdermal nitroglycerine enhances spinal neostigmine postoperative analgesia following gynecological surgery.
Topics: Administration, Cutaneous; Analgesia; Anesthesia, Spinal; Anesthetics, Local; Bupivacaine; Cholinest | 2000 |
Randomized, prospective, double-blind, placebo-controlled trial of effect of nitroglycerin ointment on pain after hemorrhoidectomy.
Topics: Administration, Topical; Dose-Response Relationship, Drug; Double-Blind Method; Drug Administration | 2001 |
The effect of transdermal nitroglycerin on spinal S(+)-ketamine antinociception following orthopedic surgery.
Topics: Adjuvants, Anesthesia; Administration, Cutaneous; Adult; Analgesia, Epidural; Analgesics; Anesthesia | 2001 |
Buccal nitroglycerin decreases ischemic pain during coronary angioplasty: a double-blind, randomized, placebo-controlled study.
Topics: Administration, Buccal; Angioplasty, Balloon, Coronary; Coronary Disease; Double-Blind Method; Human | 1990 |
4 other studies available for nitroglycerin and Acute Post-operative Pain
| Article | Year |
|---|---|
Epidural anesthesia and analgesia in liver resection and living donor hepatectomy.
Topics: Analgesia; Analgesics; Anesthesia, Epidural; Hepatectomy; Humans; Injections, Intravenous; Living Do | 2008 |
Re: Meta-analysis of the use of glyceryl trinitrate ointment after haemorrhoidectomy as an analgesic and in promoting wound healing.
Topics: Analgesics; Hemorrhoids; Humans; Meta-Analysis as Topic; Nitroglycerin; Ointments; Pain, Postoperati | 2011 |
Minimally invasive direct coronary artery bypass: anesthetic, monitoring, and pain control considerations.
Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Anesthesia, General | 1998 |
Analgesia for day surgery.
Topics: Administration, Cutaneous; Ambulatory Surgical Procedures; Analgesia; Analgesics; Humans; Nitroglyce | 1992 |