rofecoxib has been researched along with Acute Post-operative Pain in 117 studies
| Excerpt | Relevance | Reference |
|---|---|---|
| "Editor's note: The anti-inflammatory drug rofecoxib (Vioxx) was withdrawn from the market at the end of September 2004 after it was shown that long-term use (greater than 18 months) could increase the risk of heart attack and stroke in a study of secondary prevention of adenoma recurrence." | 6.45 | Single dose oral rofecoxib for acute postoperative pain in adults. ( Bulley, S; Derry, S; McQuay, HJ; Moore, RA, 2009) |
| "Rofecoxib is a selective cyclo-oxygenase (COX)-2 inhibitor which has little or no effect on the COX-1 isoenzyme at doses up to 1000 mg/day." | 6.41 | Rofecoxib: a review of its use in the management of osteoarthritis, acute pain and rheumatoid arthritis. ( Figgitt, DP; Matheson, AJ, 2001) |
| "Rofecoxib is a nonsteroidal anti-inflammatory drug that is reported to act by selectively inhibiting cyclooxygenase-2." | 5.31 | Aseptic meningitis associated with rofecoxib. ( Beitz, J; Bonnel, RA; Karwoski, CB; Villalba, ML, 2002) |
| "Rofecoxib is a selective COX-2 inhibitor that does not interfere with platelet function and is associated with fewer bleeding complications than other nonsteroidal anti-inflammatory agents (NSAIDs)." | 5.11 | Rofecoxib administration to paediatric patients undergoing adenotonsillectomy. ( Chiavacci, R; Fazi, LM; McCormick, L; Rose, JB; Sheeran, PW, 2004) |
| " We examined its effects on effort-dependent pain, postoperative morphine requirements, and pulmonary function in 48 patients recovering from open abdominal surgery." | 5.11 | Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: the effects on effort-dependent pain and pulmonary function. ( Halaszynski, T; Luther, MA; Shaheen, Y; Shen, QJ; Sinatra, RS, 2004) |
| " Rofecoxib has been demonstrated to be a valuable therapeutic agent in the management of acute orofacial pain." | 4.81 | The COX-2 inhibitors: new analgesic and anti-inflammatory drugs. ( Dionne, RA; Khan, AA, 2002) |
| "Although the published literature is limited, the data indicate that rofecoxib is an effective analgesic agent for the painful conditions in which it has been studied." | 4.81 | Rofecoxib: clinical pharmacology and clinical experience. ( Weaver, AL, 2001) |
| " As for adverse events, the incidences of nausea, vomiting, constipation, drowsiness and dizziness were similar between PRE group and POST group." | 3.01 | Efficiency and safety: comparison between preoperative analgesia and postoperative analgesia using non-steroidal anti-inflammatory drugs in patients receiving arthroscopic knee surgery in a multicenter, randomized, controlled study. ( Jiang, C; Ma, L; Wang, H; Zhang, L, 2021) |
| "The standard opioid treatment for postoperative pain can be associated with nausea, vomiting, and constipation." | 2.74 | A prospective, randomized, comparative trial of a COX-2 selective nonsteroidal anti-inflammatory drug versus placebo in inguinal herniorrhaphy patients. ( Faucher, LD; Schurr, MJ, 2009) |
| "The diurnal pattern of postoperative pain is described using pain intensity and analgesic consumption data from a recently published hysterectomy trial." | 2.73 | Chronobiological characteristics of postoperative pain: diurnal variation of both static and dynamic pain and effects of analgesic therapy. ( Boscariol, R; Gilron, I; Orr, E, 2007) |
| "The challenge of preempting postoperative pain continues and will require further investigation." | 2.73 | Prospective, double-blinded, randomized, placebo-controlled comparison of local anesthetic and nonsteroidal anti-inflammatory drugs for postoperative pain management after laparoscopic surgery. ( Heniford, BT; Hope, W; Kercher, K; Lincourt, A; Newcomb, W; Schmelzer, T; Sing, R, 2007) |
| " The limited efficacy of rofecoxib in this study contrasts to the results of previous surgical studies evaluating rofecoxib, and may be partially explained by the postoperative dosing in this arthroscopic surgical model." | 2.73 | The efficacy of rofecoxib 50 mg and hydrocodone/acetaminophen 7.5/750 mg in patients with post-arthroscopic pain. ( Chelly, JE; Nissen, CW; Rodgers, AJ; Smugar, SS; Tershakovec, AM, 2007) |
| " The following medications were randomly given to the patients who declared pain in the sixth hour after the operation: naproxen sodium, meloxicam, rofecoxib, paracetamol, dipyrone, and etodolac in proper dosage to form groups of 20 for each medication." | 2.72 | [Postoperative pain management in clinics of otolaryngology]. ( Cağici, CA; Calişkan, EE; Erkan, AN; Gencay, S; Ozlüoğlu, LN; Sener, M; Yavuz, H; Yilmaz, I; Yilmazer, C, 2006) |
| "Ibuprofen was significantly better at reducing pain at all time intervals by comparison with the placebo." | 2.72 | Ibuprofen as a pre-emptive analgesic is as effective as rofecoxib for mandibular third molar surgery. ( Kevelham, E; Morse, Z; Tump, A, 2006) |
| "Rofecoxib has a longer duration of action as a single dose and gave adequate analgesia for over half of that study group; patients in the dexketoprofen trometamol group needed more rescue analgesia." | 2.71 | Double-blind, randomized, placebo-controlled trial comparing rofecoxib with dexketoprofen trometamol in surgical dentistry. ( Brown, RD; Heidemann, BH; Jackson, ID; Power, I; Wilson, J, 2004) |
| "Rofecoxib has demonstrated an improved gastrointestinal safety profile compared with nonselective NSAIDs." | 2.71 | Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: a randomized, double-blind, placebo-controlled study in patients with moderate to severe postoperative pain in the third molar extraction model. ( Fricke, JR; Korn, S; Kotey, PN; Vassil, TC, 2004) |
| "A significant reduction in requirements for postoperative narcotic analgesic dosing was noted in the rofecoxib group." | 2.71 | Does preoperative rofecoxib (Vioxx) decrease postoperative pain with laparoscopic cholecystectomy? ( Evans, S; Horattas, MC; Lee, C; Sloan-Stakleff, KD; Snoke, JW, 2004) |
| "Rofecoxib 50 mg was significantly more effective than placebo on all measures of treatment of post-bunionectomy pain." | 2.71 | A randomized controlled study comparing rofecoxib, diclofenac sodium, and placebo in post-bunionectomy pain. ( Bird, SR; Black, PM; Chang, DJ; Daniels, S; Desjardins, PJ; Fitzgerald, BJ; Petruschke, RA; Tershakovec, A, 2004) |
| "Subjects completed a diary assessing postoperative pain onset and intensity using categorical and visual analogue scales." | 2.71 | Preemptive rofecoxib and dexamethasone for prevention of pain and trismus following third molar surgery *. ( Brar, P; Costello, BJ; Moore, PA; Smiga, ER, 2005) |
| " Fentanyl (in post-anesthesia care unit) and paracetamol (at home) were supplementary analgesics and the dosage was also recorded." | 2.71 | [Comparison of preemptive analgesia efficacy between etoricoxib and rofecoxib in ambulatory gynecological surgery]. ( Liu, W; Loo, CC; Ren, HZ; Tan, HM; Ye, TH, 2004) |
| "Rofecoxib was statistically significantly superior to codeine/acetaminophen with respect to TOPAR4, patient global assessment, peak pain relief, and duration of analgesic effect." | 2.71 | Analgesic efficacy of rofecoxib compared with codeine/acetaminophen using a model of acute dental pain. ( Bird, SR; Bohidar, NR; Chang, DJ; King, T, 2005) |
| "Effective and early treatment of postoperative pain and nausea have become pivotal for the early discharge of patients after tonsillectomy." | 2.71 | A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults. ( Ammar, MM; Gilbert, JG; Khrapov, AV; McClintock, A; Naesh, O; Niles, LA; Phibbs, PW; Phillips, AM; Robert, AJ, 2005) |
| "Finally, patient satisfaction with postoperative pain control was significantly higher in the FT group." | 2.71 | Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy. ( Cadeddu, JA; Duchene, D; Johnson, DB; Recart, A; Thomas, T; White, PF, 2005) |
| "Rofecoxib was also more effective than celecoxib in reducing pain and improving patient satisfaction after otolaryngologic surgery." | 2.71 | Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery. ( Issioui, T; Klein, KW; Watcha, MF; White, PF, 2003) |
| "The rofecoxib group was more satisfied with analgesia and anesthesia at discharge compared with the placebo group (median satisfaction score, 4." | 2.71 | Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial. ( Buvanendran, A; Elmofty, D; Kroin, JS; Lubenow, TR; Moric, M; Rosenberg, AG; Tuman, KJ, 2003) |
| "Outpatients undergoing inguinal hernia repair under general anesthesia report moderate-to-severe pain after surgery." | 2.71 | Preincisional treatment to prevent pain after ambulatory hernia surgery. ( Horvath, KD; Pavlin, DJ; Pavlin, EG; Sima, K, 2003) |
| "Rofecoxib 50 mg was superior to placebo (P < ." | 2.70 | Efficacy of single-dose and multidose rofecoxib in the treatment of post-orthopedic surgery pain. ( Bourne, M; Brown, J; deAndrade, JR; Jove, M; Krupa, D; Reicin, A; Seidenberg, B; Walters, D, 2001) |
| "Morphine consumption was recorded from a patient-controlled analgesia device at the same time." | 2.70 | Preoperative oral rofecoxib does not decrease postoperative pain or morphine consumption in patients after radical prostatectomy: a prospective, randomized, double-blinded, placebo-controlled trial. ( Andriole, GL; Hsu, H; Huang, JJ; Kurz, A; Taguchi, A, 2001) |
| "Rofecoxib is a selective cyclooxygenase-2 inhibitor indicated for the treatment of acute pain, with similar analgesic efficacy to ibuprofen and naproxen sodium." | 2.70 | Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: a randomized, placebo-controlled clinical trial. ( Chang, DJ; Chen, E; Desjardins, PJ; Geba, GP; McAvoy, M; Mockoviak, SH; Polis, AB, 2002) |
| "The morphine dose was significantly less in five of the six time intervals in the rofecoxib group compared with the celecoxib group." | 2.69 | Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery. ( Connelly, NR; Reuben, SS, 2000) |
| "Editor's note: The anti-inflammatory drug rofecoxib (Vioxx) was withdrawn from the market at the end of September 2004 after it was shown that long-term use (greater than 18 months) could increase the risk of heart attack and stroke in a study of secondary prevention of adenoma recurrence." | 2.45 | Single dose oral rofecoxib for acute postoperative pain in adults. ( Bulley, S; Derry, S; McQuay, HJ; Moore, RA, 2009) |
| "Rofecoxib is a selective cyclooxygenase-2 (COX-2) inhibitor licensed in the UK and the US for acute pain treatment and is associated with fewer gastrointestinal adverse events than conventional NSAIDs." | 2.42 | Single dose oral rofecoxib for postoperative pain. ( Barden, J; Edwards, J; McQuay, HJ; Moore, RA, 2004) |
| "Postoperative pain is acute and, although it is preventable and/or treatable, it is often undertreated." | 2.42 | The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors. ( Laskin, B; Pashos, C; Peña, B; Stephens, J; Wong, J, 2003) |
| "Management of acute postoperative pain remains suboptimal; nearly 80 % of the patients report moderate to extreme pain following surgery." | 2.42 | [Cyclooxygenase-2 inhibitors in postoperative pain management]. ( Güneş, Y; Işik, G, 2004) |
| "Valdecoxib 40 mg was also more effective than oxycodone/paracetamol 10/1000 mg (RR 1." | 2.42 | Systematic review of the analgesic efficacy and tolerability of COX-2 inhibitors in post-operative pain control. ( Ashcroft, DM; Chen, LC; Elliott, RA, 2004) |
| "Rofecoxib is a selective cyclo-oxygenase (COX)-2 inhibitor which has little or no effect on the COX-1 isoenzyme at doses up to 1000 mg/day." | 2.41 | Rofecoxib: a review of its use in the management of osteoarthritis, acute pain and rheumatoid arthritis. ( Figgitt, DP; Matheson, AJ, 2001) |
| "Rofecoxib is a nonsteroidal anti-inflammatory drug that is reported to act by selectively inhibiting cyclooxygenase-2." | 1.31 | Aseptic meningitis associated with rofecoxib. ( Beitz, J; Bonnel, RA; Karwoski, CB; Villalba, ML, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (2.56) | 18.2507 |
| 2000's | 111 (94.87) | 29.6817 |
| 2010's | 2 (1.71) | 24.3611 |
| 2020's | 1 (0.85) | 2.80 |
| Authors | Studies |
|---|---|
| Ma, L | 1 |
| Zhang, L | 1 |
| Wang, H | 1 |
| Jiang, C | 1 |
| Turaga, K | 1 |
| Wright, A | 1 |
| Lee, R | 1 |
| Dias, WP | 1 |
| Destache, C | 1 |
| Christian, R | 1 |
| Fitzgibbons, RJ | 1 |
| Schurr, MJ | 1 |
| Faucher, LD | 1 |
| Bulley, S | 1 |
| Derry, S | 1 |
| Moore, RA | 3 |
| McQuay, HJ | 3 |
| Tadros, NN | 1 |
| Bland, L | 1 |
| Legg, E | 1 |
| Olyaei, A | 1 |
| Conlin, MJ | 1 |
| Bultitude, M | 1 |
| Jeske, AH | 2 |
| Issioui, T | 2 |
| Klein, KW | 2 |
| White, PF | 4 |
| Watcha, MF | 2 |
| Skrivanek, GD | 1 |
| Jones, SB | 1 |
| Hu, J | 1 |
| Marple, BF | 1 |
| Ing, C | 1 |
| Turan, A | 2 |
| Emet, S | 1 |
| Karamanlioğlu, B | 3 |
| Memiş, D | 2 |
| Turan, N | 1 |
| Pamukcu, Z | 1 |
| Moan, A | 1 |
| Skattebøl, A | 1 |
| Khan, AA | 1 |
| Dionne, RA | 3 |
| Malmstrom, K | 2 |
| Fricke, JR | 3 |
| Kotey, P | 3 |
| Kress, B | 1 |
| Morrison, B | 1 |
| Gopikrishna, V | 1 |
| Parameswaran, A | 1 |
| Arar, C | 1 |
| Alagöl, A | 2 |
| Colak, A | 1 |
| Gemlik, I | 1 |
| Süt, N | 1 |
| Joshi, W | 2 |
| Connelly, NR | 2 |
| Reuben, SS | 7 |
| Wolckenhaar, M | 1 |
| Thakkar, N | 1 |
| Pajarola, G | 1 |
| Riva, C | 1 |
| Good, M | 1 |
| Grätz, KW | 1 |
| Stephens, J | 1 |
| Laskin, B | 1 |
| Pashos, C | 1 |
| Peña, B | 1 |
| Wong, J | 1 |
| Buvanendran, A | 1 |
| Kroin, JS | 1 |
| Tuman, KJ | 1 |
| Lubenow, TR | 1 |
| Elmofty, D | 1 |
| Moric, M | 1 |
| Rosenberg, AG | 1 |
| Coulter, DM | 1 |
| Clark, DW | 1 |
| Savage, RL | 1 |
| Pavlin, DJ | 2 |
| Horvath, KD | 2 |
| Pavlin, EG | 2 |
| Sima, K | 1 |
| Burian, M | 1 |
| Geisslinger, G | 1 |
| Sinatra, RS | 1 |
| Shen, QJ | 1 |
| Halaszynski, T | 1 |
| Luther, MA | 1 |
| Shaheen, Y | 1 |
| Bracco, P | 1 |
| Debernardi, C | 1 |
| Coscia, D | 1 |
| Pasqualini, D | 1 |
| Pasqualicchio, F | 1 |
| Calabrese, N | 1 |
| Barden, J | 2 |
| Edwards, J | 2 |
| Skinner, HB | 1 |
| Shintani, EY | 1 |
| Sari, E | 1 |
| Olmez, H | 1 |
| Gürton, AU | 1 |
| Jackson, ID | 1 |
| Heidemann, BH | 1 |
| Wilson, J | 1 |
| Power, I | 1 |
| Brown, RD | 1 |
| Karamanloğlu, B | 1 |
| Türe, M | 1 |
| Rømsing, J | 1 |
| Møiniche, S | 1 |
| Kellstein, D | 1 |
| Ott, D | 1 |
| Jayawardene, S | 1 |
| Fricke, J | 2 |
| Villa, G | 1 |
| Christensen, KS | 1 |
| Cawkwell, GD | 1 |
| Chen, LC | 1 |
| Elliott, RA | 1 |
| Ashcroft, DM | 1 |
| Sheeran, PW | 1 |
| Rose, JB | 1 |
| Fazi, LM | 1 |
| Chiavacci, R | 1 |
| McCormick, L | 1 |
| Korn, S | 1 |
| Vassil, TC | 1 |
| Kotey, PN | 1 |
| Feng, Y | 2 |
| Ju, H | 2 |
| Yang, BX | 1 |
| An, HY | 1 |
| Zhou, YY | 1 |
| Cobellis, L | 1 |
| Razzi, S | 1 |
| De Simone, S | 1 |
| Sartini, A | 1 |
| Fava, A | 1 |
| Danero, S | 1 |
| Gioffrè, W | 1 |
| Mazzini, M | 1 |
| Petraglia, F | 1 |
| Steffen, P | 1 |
| Krell, M | 1 |
| Seeling, W | 1 |
| Cabrera, MC | 1 |
| Schmied, S | 1 |
| Derderian, T | 1 |
| Vega, R | 1 |
| Santelices, E | 1 |
| Verdugo, F | 1 |
| Güneş, Y | 1 |
| Işik, G | 1 |
| Horattas, MC | 1 |
| Evans, S | 1 |
| Sloan-Stakleff, KD | 1 |
| Lee, C | 1 |
| Snoke, JW | 1 |
| Desjardins, PJ | 5 |
| Black, PM | 2 |
| Daniels, S | 2 |
| Bird, SR | 5 |
| Fitzgerald, BJ | 1 |
| Petruschke, RA | 2 |
| Tershakovec, A | 1 |
| Chang, DJ | 5 |
| Ilan, DI | 1 |
| Liporace, FA | 1 |
| Rosen, J | 1 |
| Cannavo, D | 1 |
| Kaeding, C | 1 |
| Pedroza, A | 1 |
| Sharkey, J | 1 |
| Yodfat, Y | 1 |
| Gilron, I | 2 |
| Orr, E | 2 |
| Tu, D | 1 |
| O'Neill, JP | 1 |
| Zamora, JE | 1 |
| Bell, AC | 1 |
| Zacharias, M | 1 |
| De Silva, RK | 1 |
| Herbison, P | 1 |
| Templer, P | 1 |
| Moore, PA | 1 |
| Brar, P | 1 |
| Smiga, ER | 1 |
| Costello, BJ | 1 |
| Liu, W | 1 |
| Loo, CC | 1 |
| Tan, HM | 1 |
| Ye, TH | 1 |
| Ren, HZ | 1 |
| Dahl, JB | 2 |
| Kehlet, H | 1 |
| Ablett, D | 1 |
| Kaye, R | 1 |
| Chiu, WK | 1 |
| Cheung, LK | 1 |
| Amundsen, LB | 1 |
| Flum, DR | 1 |
| Roesen, K | 1 |
| Turan, FN | 1 |
| Huang, J | 1 |
| Alanoglu, Z | 1 |
| Ateş, Y | 1 |
| Orbey, BC | 1 |
| Türkçapar, AG | 1 |
| Kim, JT | 1 |
| Sherman, O | 1 |
| Cuff, G | 1 |
| Leibovits, A | 1 |
| Wajda, M | 1 |
| Bekker, AY | 1 |
| Bohidar, NR | 2 |
| King, T | 1 |
| Meechan, J | 1 |
| Naesh, O | 1 |
| Niles, LA | 1 |
| Gilbert, JG | 1 |
| Ammar, MM | 1 |
| Phibbs, PW | 1 |
| Phillips, AM | 1 |
| Khrapov, AV | 1 |
| Robert, AJ | 1 |
| McClintock, A | 1 |
| Recart, A | 1 |
| Duchene, D | 1 |
| Thomas, T | 1 |
| Johnson, DB | 1 |
| Cadeddu, JA | 1 |
| Fornai, M | 1 |
| Colucci, R | 1 |
| Graziani, F | 1 |
| Cei, S | 1 |
| Antonioli, L | 1 |
| Tonelli, M | 1 |
| Vassalle, C | 1 |
| Blandizzi, C | 1 |
| Gabriele, M | 1 |
| Del Tacca, M | 1 |
| Riest, G | 1 |
| Peters, J | 1 |
| Weiss, M | 1 |
| Pospiech, J | 1 |
| Hoffmann, O | 1 |
| Neuhäuser, M | 1 |
| Beiderlinden, M | 1 |
| Eikermann, M | 1 |
| Babul, N | 1 |
| Sloan, P | 1 |
| Lipman, AG | 1 |
| Schuster, R | 1 |
| Stewart, D | 1 |
| Schuster, L | 1 |
| Greaney, G | 1 |
| Waxman, K | 1 |
| Louizos, AA | 1 |
| Pandazi, AB | 1 |
| Koraka, CP | 1 |
| Davilis, DI | 1 |
| Georgiou, LG | 1 |
| Church, CA | 1 |
| Stewart, C | 1 |
| O-Lee, TJ | 1 |
| Wallace, D | 1 |
| Hovsepian, DM | 1 |
| Mandava, A | 1 |
| Pilgram, TK | 1 |
| Holder, AP | 1 |
| Wong, V | 1 |
| Chan, P | 1 |
| Patel, T | 1 |
| Lee, YS | 1 |
| Kim, H | 1 |
| Wu, TX | 1 |
| Wang, XM | 2 |
| Jacobson, E | 1 |
| Assareh, H | 1 |
| Cannerfelt, R | 1 |
| Renström, P | 1 |
| Jakobsson, J | 1 |
| Yilmaz, I | 1 |
| Sener, M | 1 |
| Yavuz, H | 1 |
| Yilmazer, C | 1 |
| Erkan, AN | 1 |
| Cağici, CA | 1 |
| Gencay, S | 1 |
| Calişkan, EE | 1 |
| Ozlüoğlu, LN | 1 |
| Mikkelsen, S | 1 |
| Hilsted, KL | 1 |
| Andersen, PJ | 1 |
| Hjortsø, NC | 1 |
| Enggaard, TP | 1 |
| Jørgensen, DG | 1 |
| Hansen, M | 1 |
| Henriksen, J | 1 |
| Haglund, B | 1 |
| von Bültzingslöwen, I | 1 |
| Daniels, SE | 2 |
| Smugar, SS | 3 |
| Tershakovec, AM | 3 |
| Morse, Z | 1 |
| Tump, A | 1 |
| Kevelham, E | 1 |
| Rahimi, SY | 1 |
| Vender, JR | 1 |
| Macomson, SD | 1 |
| French, A | 1 |
| Smith, JR | 1 |
| Alleyne, CH | 1 |
| Michael Hill, C | 1 |
| Sindet-Pederson, S | 1 |
| Seymour, RA | 1 |
| Hawkesford, JE | 1 |
| Coulthard, P | 1 |
| Lamey, PJ | 1 |
| Gerry Cowan, C | 1 |
| Wickens, M | 1 |
| Jeppsson, L | 1 |
| Dean, AD | 1 |
| Svensson, O | 1 |
| Chelly, JE | 1 |
| Nissen, CW | 1 |
| Rodgers, AJ | 1 |
| Hval, K | 1 |
| Kjetil, H | 1 |
| Thagaard, KS | 1 |
| Sem, TK | 1 |
| Schlichting, E | 1 |
| Ellen, S | 1 |
| Raeder, J | 1 |
| Johan, R | 1 |
| Newcomb, W | 1 |
| Lincourt, A | 1 |
| Hope, W | 1 |
| Schmelzer, T | 1 |
| Sing, R | 1 |
| Kercher, K | 1 |
| Heniford, BT | 1 |
| Antonetti, M | 1 |
| Kirton, O | 1 |
| Bui, P | 1 |
| Ademi, A | 1 |
| Staff, I | 1 |
| Hudson-Civetta, JA | 1 |
| Lilly, R | 1 |
| Boscariol, R | 1 |
| Bean-Lijewski, JD | 1 |
| Kruitbosch, SH | 1 |
| Hutchinson, L | 1 |
| Browne, B | 1 |
| Yang, B | 1 |
| An, H | 1 |
| Vallée, E | 1 |
| Carignan, M | 1 |
| Lafrenaye, S | 1 |
| Dorion, D | 1 |
| Gordon, SM | 1 |
| Chuang, BP | 1 |
| Hamza, MA | 1 |
| Rowan, JS | 1 |
| Brahim, JS | 1 |
| Morrison, BW | 2 |
| Christensen, S | 1 |
| Yuan, W | 2 |
| Brown, J | 3 |
| Amlani, S | 1 |
| Seidenberg, B | 2 |
| Seidenberg, BC | 1 |
| Mehlisch, D | 1 |
| Reicin, A | 1 |
| Jove, M | 1 |
| deAndrade, JR | 1 |
| Bourne, M | 1 |
| Krupa, D | 1 |
| Walters, D | 1 |
| Huang, JJ | 1 |
| Taguchi, A | 1 |
| Hsu, H | 1 |
| Andriole, GL | 1 |
| Kurz, A | 1 |
| Matheson, AJ | 1 |
| Figgitt, DP | 1 |
| Weaver, AL | 1 |
| Dobbins, TW | 1 |
| Geba, GP | 2 |
| Burgess, FW | 1 |
| Browning, RA | 1 |
| Bhopatkar, S | 1 |
| Maciolek, H | 2 |
| Sklar, J | 1 |
| Fingeroth, R | 1 |
| Krushell, R | 1 |
| Pickering, AE | 1 |
| Bridge, HS | 1 |
| Nolan, J | 1 |
| Stoddart, PA | 1 |
| Foral, PA | 1 |
| Wilson, AF | 1 |
| Nystrom, KK | 1 |
| Bonnel, RA | 1 |
| Villalba, ML | 1 |
| Karwoski, CB | 1 |
| Beitz, J | 1 |
| Bekker, A | 1 |
| Cooper, PR | 1 |
| Frempong-Boadu, A | 1 |
| Babu, R | 1 |
| Errico, T | 1 |
| Lebovits, A | 1 |
| Chen, E | 1 |
| Polis, AB | 1 |
| McAvoy, M | 1 |
| Mockoviak, SH | 1 |
| Meyer, R | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Double-blind, Placebo-controlled Randomized Controlled Trial of NSAID Prior to Ureteral Stent Removal in a Pediatric Population[NCT02140970] | 51 participants (Actual) | Interventional | 2014-05-31 | Completed | |||
| The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Cesarean Delivery[NCT02257346] | 0 participants (Actual) | Interventional | 2014-11-01 | Withdrawn (stopped due to PI terminated study with no subjects enrolled.) | |||
| The Effect of Perioperative Systemic Lidocaine on Quality of Recovery After Outpatient Gynecologic Laparoscopy[NCT01250002] | 70 participants (Actual) | Interventional | 2010-11-30 | Completed | |||
| Erector Spinae Plane Block (ESPB): A New Technique for Perioperative Pain Control in Patients Undergoing Surgery Through a Flank or Anterior Subcostal Incision.[NCT03691935] | Phase 4 | 40 participants (Anticipated) | Interventional | 2018-09-28 | Enrolling by invitation | ||
| A Pilot Study of Bupivacaine Infusion in Abdominal Surgery[NCT00280553] | Phase 2 | 60 participants (Anticipated) | Interventional | 2005-04-30 | Recruiting | ||
| Opioid Requirements Post Discharge of Patients Having Total Knee Arthroplasty (TKA)[NCT03106129] | 200 participants (Anticipated) | Observational | 2017-02-09 | Active, not recruiting | |||
| Parecoxib as an Adjuvant to Scalp Nerve Blocks for Relief of Post-craniotomy Pain[NCT04034836] | Phase 4 | 132 participants (Anticipated) | Interventional | 2019-10-12 | Recruiting | ||
| Towards Predicting the Analgesic Response to Ibuprofen Following Third-molar Extraction[NCT03893175] | Phase 1 | 86 participants (Actual) | Interventional | 2019-05-10 | Completed | ||
| A Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled, Parallel-Group Study of Rofecoxib and Diclofenac Sodium in the Treatment of Post-Bunionectomy Surgery Pain[NCT00092378] | Phase 3 | 251 participants (Actual) | Interventional | 2003-09-01 | Completed | ||
| Analgesic Effect of Pregabalin in Patients Undergoing Total Abdominal Hysterectomy[NCT01466101] | 0 participants (Actual) | Interventional | 2011-01-31 | Withdrawn (stopped due to PI left the institution. No subjects screened or enrolled.) | |||
| Effect of Toradol on Post-operative Foot and Ankle Healing[NCT03727048] | Phase 4 | 128 participants (Actual) | Interventional | 2016-08-31 | Completed | ||
| Ultrasound-Guided Submandibular Parapharyngeal Glossopharyngeal Nerve Block for Post -Tonsillectomy Pain Relief in Adults. A Prospective Randomized Study[NCT05435833] | 50 participants (Actual) | Interventional | 2022-11-05 | Completed | |||
| Post-tonsillectomy Pain Control in Adults: a Randomized Prospective Study[NCT02358850] | Phase 4 | 27 participants (Actual) | Interventional | 2016-01-31 | Terminated (stopped due to low enrollment) | ||
| Ambulant Laparoscopic Nephrectomy[NCT01600157] | 62 participants (Actual) | Interventional | 2013-04-30 | Completed | |||
| Effect of Celecoxib on Postoperative Narcotic Use and Disease Severity in Patients With Aspirin-exacerbated Respiratory Disease and Chronic Rhinosinusitis: a Randomised Controlled Trial[NCT04147013] | Phase 4 | 44 participants (Anticipated) | Interventional | 2020-02-18 | Recruiting | ||
| Effect of Gabapentin on Postoperative Opioid Analgesic Use and Pain in Adolescents Undergoing Tonsillectomy[NCT05024825] | Phase 4 | 17 participants (Actual) | Interventional | 2017-08-04 | Terminated (stopped due to recruitment target not met.) | ||
| A Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled, Single Dose Study of the Effect of Rofecoxib 50 mg and Valdecoxib 20 mg in Patients With Postoperative Dental Pain[NCT00092300] | Phase 3 | 450 participants | Interventional | 2002-05-31 | Completed | ||
| A Randomized, Double-Blind, Placebo-Controlled, Single-Dose Study to Evaluate the Effects of Rofecoxib 50 mg and Valdecoxib 40 mg in Patients With Postoperative Dental Pain[NCT00092339] | Phase 3 | 125 participants (Anticipated) | Interventional | 2002-08-01 | Completed | ||
| The Effect of Steroid on Reducing Facial Swelling After Orthognathic Surgery[NCT01431014] | Phase 4 | 56 participants (Actual) | Interventional | 2011-08-31 | Completed | ||
| Randomized, Double-Blind, Placebo-Controlled Trial of the Effect of Rofecoxib 50 mg and Hydrocodone 7.5 mg With Acetaminophen 750 mg in Patients With Postoperative Arthroscopic Pain[NCT00390260] | Phase 3 | 420 participants | Interventional | 2002-02-28 | Completed | ||
| A Randomized, Double-Blind, Placebo- and Active-Comparator-Controlled Study to Evaluate the Efficacy of Rofecoxib and a Dosing Regimen of Oxycodone With Acetaminophen Over 24 Hours in Patients With Postoperative Dental Pain[NCT00092326] | Phase 3 | 269 participants (Actual) | Interventional | 2002-06-30 | Completed | ||
| Randomized Clinical Trial of Non-Opioid Pain Medications After Adenotonsillectomy[NCT03618823] | Phase 1/Phase 2 | 268 participants (Actual) | Interventional | 2018-10-25 | Terminated (stopped due to Early termination due to COVID-19 cases and cancelled surgeries.) | ||
| Use of a Non-Opioid Pain Regimen for Post-Operative Analgesia Following Intracapsular Adenotonsillectomy[NCT04791761] | Phase 1/Phase 2 | 300 participants (Anticipated) | Interventional | 2021-04-13 | Recruiting | ||
| Cytokine Responses to Acute Inflammation in the Oral Surgery Model[NCT00006175] | 160 participants | Observational | 2000-08-31 | Completed | |||
| MORphine Use in the Fascia Iliaca Compartment Block With UltraSound[NCT03846102] | Phase 4 | 55 participants (Actual) | Interventional | 2019-01-28 | Terminated (stopped due to COVID-19 crisis.) | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
"Incidence of significantly worsening pain is defined as any increase ≥ 2 between the pre-operative and post-operative pain scale assessments" (NCT02140970)
Timeframe: 24 hours after stent removal
| Intervention | Participants (Count of Participants) |
|---|---|
| Liquid Ibuprofen | 3 |
| Liquid Placebo | 5 |
Pain will be assessed via a 10 point [NAME OF SCALE] scale. Possible scores range from 0 to 10, with higher scores indicating more severe pain and a worse outcome. (NCT02140970)
Timeframe: 24 hours after stent removal
| Intervention | score on a scale (Mean) |
|---|---|
| Liquid Ibuprofen | 0.4 |
| Liquid Placebo | 0.2 |
Two pain scales were used (Faces pain scale-revised [FPS-R] and visual analogue scale [VAS]) and converted to continuous value 0-10. (NCT02140970)
Timeframe: 24 hours after stent removal
| Intervention | Participants (Count of Participants) |
|---|---|
| Liquid Ibuprofen | 2 |
| Liquid Placebo | 1 |
This will be recorded in equivalents to milligrams intravenous morphine (NCT02140970)
Timeframe: 24 hours after stent removal
| Intervention | mg/kg (Mean) |
|---|---|
| Liquid Ibuprofen | 0.0 |
| Liquid Placebo | 0.0 |
opioid consumption (morphine equivalents)post operatively (NCT01250002)
Timeframe: 24 hours
| Intervention | mg (Median) |
|---|---|
| Group A (Study Group) Lidocaine | 20 |
| Placebo | 30 |
Quality of recovery 40 score on the day after surgery. Scale ranges from a low of 40 (poor recovery) to a high of 200 (good recovery). (NCT01250002)
Timeframe: 24 hours post surgery
| Intervention | units on a scale (Median) |
|---|---|
| Group A (Study Group) Lidocaine | 175 |
| Placebo | 157.5 |
Measure of facial swelling will be performed using 3-dimensional photogrammetry. The 3d photo acquisition is non-invasive without radiation concern. The images will be taken before and after surgery to measure and compare the degree of facial swelling. Side effects from the steroid use are expected to be low under normal clinical dosage, but will also be monitored. Symptoms of wound infection, psychosis, and prolonged wound healing will be studied. There should be no long term complication, since the steroid use is one single dose. (NCT01431014)
Timeframe: 1 year
| Intervention | ml (Mean) | ||
|---|---|---|---|
| 36 hours postoperatively | 1week postoperatively | 1month postoperatively | |
| "DexamethasoneHigh-dose" | 167.06 | 61.39 | 29.85 |
| "DexamethasoneLow-dose" | 190.73 | 57.62 | 19.34 |
Number of non-opioid group members switching to receiving opioid medication - assessed via the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Non-opioid Pain Control | 7 |
Number of participants with emergency department or urgent care visits in 14 post-operative days - assessed via the electronic medical record and the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Opioid Pain Control | 8 |
| Non-opioid Pain Control | 11 |
Number of participants with hospitalizations after discharge in 14 days - assessed using the electronic medical record and the take-home pain diary. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Participants (Count of Participants) |
|---|---|
| Opioid Pain Control | 3 |
| Non-opioid Pain Control | 8 |
"Score assigned by the patient at the end of 14 post-operative days in the take-home pain diary using a Likert scale. Patients will respond to the following statement I am happy with the pain relief I received in the last 14 days with responses ranging from strongly agree to strongly disagree. The responses will be assigned a numerical value, from 0 (strongly disagree) to 4 (strongly agree), and the average value for all subjects in the group will be reported as the overall pain relief satisfaction. Higher scores mean a better outcome." (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | score on a scale (Mean) |
|---|---|
| Opioid Pain Control | 3.35 |
| Non-opioid Pain Control | 3.09 |
Number of post-operative phone calls to nursing staff, obtained using the electronic medical record. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | post-operative phone calls (Mean) |
|---|---|
| Opioid Pain Control | 0.35 |
| Non-opioid Pain Control | 0.47 |
In the take-home pain diary, patients will record the amount of medication taken for each dose. The mean value of these doses will be calculated and averaged within each group to determine the average dose of each analgesic used. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Milliliters (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 7.52 | 7.53 | 0.04 |
| Opioid Pain Control | 6.54 | 7.53 | 0.13 |
Average pain over 14 post-operative days before and after medications. This is quantified using the validated Wong-Baker FACES pain metric. Patients receive a take-home pain diary and for 14 days report their maximum pain both before and after taking pain medication. The mean of these pain ratings will be the primary outcome measure. The Wong-Baker FACES scale is from 0 (min) to 10 (max). A higher score indicates worse outcome/pain. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Score on a scale (Mean) | |
|---|---|---|
| Before | After | |
| Non-opioid Pain Control Group | 5.66 | 2.24 |
| Opioid Pain Control Group | 5.78 | 2.33 |
Using the results of the take-home pain diary, we will calculate the average number of days of use of each analgesic for each group. The last day after which there is no subsequent use of analgesic will define the end-point of the duration of use. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | days (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 8.64 | 8.75 | 0.45 |
| Opioid Pain Control | 8.61 | 8.49 | 2.62 |
Using the take-home pain diary, the total amount in mL of each analgesic used over 14 days by each patient in a group will be averaged and reported. (NCT03618823)
Timeframe: 14 days post-operatively
| Intervention | Milliliters (Mean) | ||
|---|---|---|---|
| Acetaminophen | Ibuprofen | Oxycodone | |
| Non-opioid Pain Control | 326.98 | 334.65 | 2.96 |
| Opioid Pain Control | 292.48 | 324.14 | 6.47 |
15 reviews available for rofecoxib and Acute Post-operative Pain
| Article | Year |
|---|---|
Single dose oral rofecoxib for acute postoperative pain in adults.
Topics: Acute Disease; Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2009 |
Selecting new drugs for pain control: evidence-based decisions or clinical impressions?
Topics: Acute Disease; Anti-Inflammatory Agents, Non-Steroidal; Chronic Disease; Clinical Trials as Topic; C | 2002 |
The COX-2 inhibitors: new analgesic and anti-inflammatory drugs.
Topics: Analgesics, Non-Narcotic; Anti-Inflammatory Agents; Anti-Inflammatory Agents, Non-Steroidal; Cycloox | 2002 |
The burden of acute postoperative pain and the potential role of the COX-2-specific inhibitors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cost of Illness; Cyclooxygenase 2; Cyclooxygenas | 2003 |
Celecoxib, rofecoxib, and acute temporary visual impairment.
Topics: Acute Disease; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxy | 2003 |
[Clinical pharmacology of the selective COX-2 inhibitors].
Topics: Acute Disease; Administration, Oral; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis | 2003 |
Single dose oral rofecoxib for postoperative pain.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Lactones; Pain, P | 2004 |
A systematic review of COX-2 inhibitors compared with traditional NSAIDs, or different COX-2 inhibitors for post-operative pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Isoxazoles; L | 2004 |
Systematic review of the analgesic efficacy and tolerability of COX-2 inhibitors in post-operative pain control.
Topics: Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenas | 2004 |
[Cyclooxygenase-2 inhibitors in postoperative pain management].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Humans; Lactones; Pai | 2004 |
[Is there a future for COX-2 inhibitors?].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Cyclooxygenase 2; Cyclooxygenase 2 I | 2004 |
Single dose oral rofecoxib for postoperative pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Dru | 2005 |
COX-2 inhibitors and dental pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Contraindications; Cyclooxygenase Inhibitors; Fa | 1999 |
Rofecoxib: a review of its use in the management of osteoarthritis, acute pain and rheumatoid arthritis.
Topics: Acute Disease; Animals; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Clinical Tri | 2001 |
Rofecoxib: clinical pharmacology and clinical experience.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Humans; Lactones; Osteoarthritis; Pa | 2001 |
81 trials available for rofecoxib and Acute Post-operative Pain
| Article | Year |
|---|---|
Efficiency and safety: comparison between preoperative analgesia and postoperative analgesia using non-steroidal anti-inflammatory drugs in patients receiving arthroscopic knee surgery in a multicenter, randomized, controlled study.
Topics: Adult; Analgesia; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Celecoxib; Female; Humans; K | 2021 |
A randomized trial of the peri-operative use of COX-2 inhibitors in Lichtenstein herniorrhaphy.
Topics: Adult; Aged; Aged, 80 and over; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Cyclooxyge | 2008 |
A prospective, randomized, comparative trial of a COX-2 selective nonsteroidal anti-inflammatory drug versus placebo in inguinal herniorrhaphy patients.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents; Cyclooxygenase 2 Inhibitors; Female; Hernia, Ingu | 2009 |
A single dose of a non-steroidal anti-inflammatory drug (NSAID) prevents severe pain after ureteric stent removal: a prospective, randomised, double-blind, placebo-controlled trial.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; Device Removal; Double- | 2013 |
Cost-efficacy of rofecoxib versus acetaminophen for preventing pain after ambulatory surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; An | 2002 |
Analgesic effects of rofecoxib in ear-nose-throat surgery.
Topics: Adult; Analgesics, Opioid; Anesthetics, Local; Blood Pressure; Cyclooxygenase 2; Cyclooxygenase 2 In | 2002 |
A comparison of rofecoxib versus celecoxib in treating pain after dental surgery: a single-center, randomized, double-blind, placebo- and active-comparator-controlled, parallel-group, single-dose study using the dental impaction pain model.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitor | 2002 |
Effectiveness of prophylactic use of rofecoxib in comparison with ibuprofen on postendodontic pain.
Topics: Acute Disease; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Costs and effectiveness of rofecoxib, celecoxib, and acetaminophen for preventing pain after ambulatory otolaryngologic surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Celecoxi | 2003 |
Preoperative oral celecoxib versus preoperative oral rofecoxib for pain relief after thyroid surgery.
Topics: Adult; Analgesics, Opioid; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Blood Pres | 2003 |
An evaluation of the safety and efficacy of administering rofecoxib for postoperative pain management.
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2003 |
[Pain management after third molar extraction. Observations of the use of mefenamic acid and rofecoxib in the treatment of postoperative pain in the dental office].
Topics: Adult; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cy | 2003 |
Effects of perioperative administration of a selective cyclooxygenase 2 inhibitor on pain management and recovery of function after knee replacement: a randomized controlled trial.
Topics: Adult; Aged; Analgesia, Epidural; Analgesia, Patient-Controlled; Analgesics, Opioid; Arthroplasty, R | 2003 |
Preincisional treatment to prevent pain after ambulatory hernia surgery.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Anti-Inflammatory Agents, Non-Steroidal; Cy | 2003 |
Preoperative rofecoxib oral suspension as an analgesic adjunct after lower abdominal surgery: the effects on effort-dependent pain and pulmonary function.
Topics: Abdomen; Aged; Analgesics, Opioid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inh | 2004 |
Efficacy of rofecoxib and nimesulide in controlling postextraction pain in oral surgery: a randomised comparative study.
Topics: Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Female; Humans; Lactones; Ma | 2004 |
Comparison of some effects of acetylsalicylic acid and rofecoxib during orthodontic tooth movement.
Topics: Adolescent; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Cyclooxygenase Inhibitors; Dinoproston | 2004 |
Double-blind, randomized, placebo-controlled trial comparing rofecoxib with dexketoprofen trometamol in surgical dentistry.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclo | 2004 |
Preoperative oral rofecoxib reduces postoperative pain and tramadol consumption in patients after abdominal hysterectomy.
Topics: Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, General; Antiemetics; Cy | 2004 |
Analgesic efficacy of a single dose of lumiracoxib compared with rofecoxib, celecoxib and placebo in the treatment of post-operative dental pain.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase Inhibitors; Di | 2004 |
Valdecoxib versus rofecoxib in acute postsurgical pain: results of a randomized controlled trial.
Topics: Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Cyclooxygenase Inhibitors; Double-Blind | 2004 |
Rofecoxib administration to paediatric patients undergoing adenotonsillectomy.
Topics: Adenoidectomy; Child; Child, Preschool; Cyclooxygenase Inhibitors; Double-Blind Method; Drug Adminis | 2004 |
Comparison of rofecoxib and oxycodone plus acetaminophen in the treatment of acute pain: a randomized, double-blind, placebo-controlled study in patients with moderate to severe postoperative pain in the third molar extraction model.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Doubl | 2004 |
[Postoperative analgesic and anti-inflammatory effects of rofecoxib after total knee replacement].
Topics: Administration, Oral; Aged; Analgesia, Epidural; Anti-Inflammatory Agents; Arthroplasty, Replacement | 2004 |
The treatment with a COX-2 specific inhibitor is effective in the management of pain related to endometriosis.
Topics: Adult; Cyclooxygenase Inhibitors; Double-Blind Method; Endometriosis; Female; Gynecologic Surgical P | 2004 |
[Postoperative analgesia with rofecoxib. How effective is the preoperative application of a 25 mg dose?].
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Double-Blind Method; Female; Humans; Lactones; | 2004 |
Efficacy of oral rofecoxib versus intravenous ketoprofen as an adjuvant to PCA morphine after urologic surgery.
Topics: Administration, Oral; Adult; Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Anesthesia, Sp | 2004 |
Does preoperative rofecoxib (Vioxx) decrease postoperative pain with laparoscopic cholecystectomy?
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Cholecystectomy, Laparoscopic; Double-Blind Method; | 2004 |
A randomized controlled study comparing rofecoxib, diclofenac sodium, and placebo in post-bunionectomy pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Metho | 2004 |
A randomized controlled study comparing rofecoxib, diclofenac sodium, and placebo in post-bunionectomy pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Metho | 2004 |
A randomized controlled study comparing rofecoxib, diclofenac sodium, and placebo in post-bunionectomy pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Metho | 2004 |
A randomized controlled study comparing rofecoxib, diclofenac sodium, and placebo in post-bunionectomy pain.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Double-Blind Metho | 2004 |
Efficacy of rofecoxib for pain control after knee arthroscopy: a prospective, randomized, double-blinded clinical trial.
Topics: Acute Disease; Adult; Arthroscopy; Double-Blind Method; Drug Administration Schedule; Humans; Knee J | 2004 |
Comparison of efficacy of oral rofecoxib and ketorolac in controlling early postoperative outpatient orthopedic surgical pain.
Topics: Administration, Oral; Adolescent; Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2004 |
A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hysterectomy.
Topics: Adult; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Double- | 2005 |
A randomized crossover trial of tenoxicam compared with rofecoxib for postoperative dental pain control.
Topics: Adolescent; Adult; Confidence Intervals; Cross-Over Studies; Cyclooxygenase Inhibitors; Dose-Respons | 2004 |
Preemptive rofecoxib and dexamethasone for prevention of pain and trismus following third molar surgery *.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Double-Blind Method; Drug | 2005 |
[Comparison of preemptive analgesia efficacy between etoricoxib and rofecoxib in ambulatory gynecological surgery].
Topics: Abortion, Induced; Acetaminophen; Adolescent; Adult; Ambulatory Surgical Procedures; Analgesics, Non | 2004 |
Efficacy of preoperative oral rofecoxib in pain control for third molar surgery.
Topics: Administration, Oral; Adult; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cross-Ov | 2005 |
Perioperative rofecoxib plus local anesthetic field block diminishes pain and recovery time after outpatient inguinal hernia repair.
Topics: Adolescent; Adult; Aged; Ambulatory Surgical Procedures; Analgesics, Opioid; Anesthesia Recovery Per | 2005 |
Preemptive oral rofecoxib plus postoperative intraarticular bupivacaine for pain relief after arthroscopic knee surgery.
Topics: Administration, Oral; Adult; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Arthroscop | 2005 |
Preoperative use of selective COX-II inhibitors for pain management in laparoscopic nissen fundoplication.
Topics: Adult; Celecoxib; Cyclooxygenase 2 Inhibitors; Diclofenac; Double-Blind Method; Female; Fundoplicati | 2005 |
A double-blind prospective comparison of rofecoxib vs ketorolac in reducing postoperative pain after arthroscopic knee surgery.
Topics: Adult; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; Cyclooxygenase 2 In | 2005 |
Analgesic efficacy of rofecoxib compared with codeine/acetaminophen using a model of acute dental pain.
Topics: Acetaminophen; Acute Disease; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analy | 2005 |
COX-2 inhibitors and pain after oral surgery - pertinent papers 2002-2003.
Topics: Administration, Oral; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2 Inhibitor | 2006 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
A randomized, placebo-controlled study of rofecoxib with paracetamol in early post-tonsillectomy pain in adults.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Cyclooxygenase 2 Inh | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Efficacy and safety of fast-track recovery strategy for patients undergoing laparoscopic nephrectomy.
Topics: Acetaminophen; Adult; Aged; Analgesics; Antiemetics; Cyclooxygenase 2 Inhibitors; Female; Histamine | 2005 |
Cyclooxygenase-2 induction after oral surgery does not entirely account for analgesia after selective blockade of cyclooxygenase 2 in the preoperative period.
Topics: Actins; Adult; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Dinoprostone; Double | 2006 |
Does perioperative administration of rofecoxib improve analgesia after spine, breast and orthopaedic surgery?
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Analgesics, Opioid; Arthroplasty, Replacement, Hip; Arth | 2006 |
Preoperative oral rofecoxib and postoperative pain in patients after laparoscopic cholecystectomy: a prospective, randomized, double-blinded, placebo-controlled trial.
Topics: Administration, Oral; Analgesics, Opioid; Cholecystectomy, Laparoscopic; Cholelithiasis; Cyclooxygen | 2005 |
Preoperative administration of rofecoxib versus ketoprofen for pain relief after tonsillectomy.
Topics: Administration, Oral; Adult; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2 Inhibitors; F | 2006 |
Rofecoxib versus hydrocodone/acetaminophen for postoperative analgesia in functional endoscopic sinus surgery.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Analgesia; Analgesics, Non-Narcotic; Anal | 2006 |
Comparison of adjunctive use of rofecoxib versus ibuprofen in the management of postoperative pain after uterine artery embolization.
Topics: Adult; Aged; Chi-Square Distribution; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Embolization | 2006 |
Genetically mediated interindividual variation in analgesic responses to cyclooxygenase inhibitory drugs.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 1; Cyclooxygenase 2; Cyclooxygenase Inhibitors; Female; Hapl | 2006 |
Pain after elective arthroscopy of the knee: a prospective, randomised, study comparing conventional NSAID to coxib.
Topics: Adolescent; Adult; Aged; Anesthesia, General; Anti-Inflammatory Agents, Non-Steroidal; Arthroscopy; | 2006 |
[Postoperative pain management in clinics of otolaryngology].
Topics: Acetaminophen; Adolescent; Adult; Aged; Analgesics; Dipyrone; Etodolac; Female; Humans; Lactones; Ma | 2006 |
The effect of gabapentin on post-operative pain following tonsillectomy in adults.
Topics: Adolescent; Adult; Amines; Analgesics; Analgesics, Opioid; Cyclohexanecarboxylic Acids; Cyclooxygena | 2006 |
Combining paracetamol with a selective cyclooxygenase-2 inhibitor for acute pain relief after third molar surgery: a randomized, double-blind, placebo-controlled study.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Cohort Studies; Cyclooxygenase 2 Inhibitors; Double- | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Rofecoxib 50 mg and valdecoxib 20 or 40 mg in adults and adolescents with postoperative pain after third molar extraction: results of two randomized, double-blind, placebo-controlled, single-dose studies.
Topics: Adolescent; Adult; Aged; Cyclooxygenase 2 Inhibitors; Double-Blind Method; Female; Humans; Isoxazole | 2006 |
Ibuprofen as a pre-emptive analgesic is as effective as rofecoxib for mandibular third molar surgery.
Topics: Adolescent; Adult; Aged; Analysis of Variance; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygena | 2006 |
Postoperative pain management after craniotomy: evaluation and cost analysis.
Topics: Acetaminophen; Adult; Aged; Analgesics, Non-Narcotic; Craniotomy; Cyclooxygenase 2 Inhibitors; Dose- | 2006 |
Analgesic efficacy of the cyclooxygenase-inhibiting nitric oxide donor AZD3582 in postoperative dental pain: Comparison with naproxen and rofecoxib in two randomized, double-blind, placebo-controlled studies.
Topics: Adolescent; Adult; Cyclooxygenase Inhibitors; Dose-Response Relationship, Drug; Double-Blind Method; | 2006 |
The efficacy of rofecoxib 50 mg and hydrocodone/acetaminophen 7.5/750 mg in patients with post-arthroscopic pain.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Analysis of Variance; Arthroscop | 2007 |
The prolonged postoperative analgesic effect when dexamethasone is added to a nonsteroidal antiinflammatory drug (rofecoxib) before breast surgery.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Breast Neoplasms; Dexamethasone; Double-Blind Method | 2007 |
A double-blind randomized controlled trial of rofecoxib and multidose oxycodone/acetaminophen in dental impaction pain.
Topics: Acetaminophen; Adult; Analgesics; Cyclooxygenase 2 Inhibitors; Dose-Response Relationship, Drug; Dou | 2007 |
Prospective, double-blinded, randomized, placebo-controlled comparison of local anesthetic and nonsteroidal anti-inflammatory drugs for postoperative pain management after laparoscopic surgery.
Topics: Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Bupivacaine; Cholecystectom | 2007 |
The effects of preoperative rofecoxib, metoclopramide, dexamethasone, and ondansetron on postoperative pain and nausea in patients undergoing elective laparoscopic cholecystectomy.
Topics: Antiemetics; Cholecystectomy, Laparoscopic; Cyclooxygenase 2 Inhibitors; Dexamethasone; Double-Blind | 2007 |
Chronobiological characteristics of postoperative pain: diurnal variation of both static and dynamic pain and effects of analgesic therapy.
Topics: Amines; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Circadian Rhythm; Cyclohexane | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Post-tonsillectomy pain management in children: can we do better?
Topics: Acetaminophen; Adolescent; Ambulatory Surgical Procedures; Analgesics, Non-Narcotic; Analgesics, Opi | 2007 |
Effects of a selective cyclooxygenase-2 inhibitor on postoperative inflammatory reaction and pain after total knee replacement.
Topics: Administration, Oral; Aged; Analgesics, Opioid; Arthritis; Arthroplasty, Replacement, Knee; Chemotax | 2008 |
Comparative study of acetaminophen-morphine versus rofecoxib-morphine for post-tonsillectomy pain control.
Topics: Acetaminophen; Adolescent; Analgesics, Opioid; Child; Child, Preschool; Cyclooxygenase 2 Inhibitors; | 2007 |
The differential effects of bupivacaine and lidocaine on prostaglandin E2 release, cyclooxygenase gene expression and pain in a clinical pain model.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Anesthetics, Local; | 2008 |
Analgesic efficacy of the cyclooxygenase-2-specific inhibitor rofecoxib in post-dental surgery pain: a randomized, controlled trial.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxy | 1999 |
Comparison of rofecoxib and celecoxib, two cyclooxygenase-2 inhibitors, in postoperative dental pain: a randomized, placebo- and active-comparator-controlled clinical trial.
Topics: Adult; Celecoxib; Cyclooxygenase Inhibitors; Double-Blind Method; Enzyme Inhibitors; Female; Humans; | 1999 |
Postoperative analgesic effects of celecoxib or rofecoxib after spinal fusion surgery.
Topics: Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; C | 2000 |
The optimal analgesic dose of rofecoxib: Overview of six randomized controlled trials.
Topics: Adolescent; Adult; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase | 2000 |
Efficacy of single-dose and multidose rofecoxib in the treatment of post-orthopedic surgery pain.
Topics: Adult; Cyclooxygenase Inhibitors; Double-Blind Method; Female; Humans; Lactones; Male; Naproxen; Ort | 2001 |
Preoperative oral rofecoxib does not decrease postoperative pain or morphine consumption in patients after radical prostatectomy: a prospective, randomized, double-blinded, placebo-controlled trial.
Topics: Aged; Analgesia, Patient-Controlled; Analgesics, Opioid; Cyclooxygenase 2; Cyclooxygenase 2 Inhibito | 2001 |
Rofecoxib versus codeine/acetaminophen in postoperative dental pain: a double-blind, randomized, placebo- and active comparator-controlled clinical trial.
Topics: Acetaminophen; Adolescent; Adult; Analgesics, Non-Narcotic; Analgesics, Opioid; Codeine; Double-Blin | 2001 |
The preemptive analgesic effect of rofecoxib after ambulatory arthroscopic knee surgery.
Topics: Adult; Ambulatory Surgical Procedures; Analgesics; Anesthetics, Local; Anti-Inflammatory Agents, Non | 2002 |
Evaluation of the safety and efficacy of the perioperative administration of rofecoxib for total knee arthroplasty.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty, Replacement, Knee; Cyclooxygenase 2; Cy | 2002 |
Double-blind, placebo-controlled analgesic study of ibuprofen or rofecoxib in combination with paracetamol for tonsillectomy in children.
Topics: Acetaminophen; Adenoidectomy; Adolescent; Analgesics, Non-Narcotic; Anti-Inflammatory Agents, Non-St | 2002 |
Evaluation of preoperative administration of the cyclooxygenase-2 inhibitor rofecoxib for the treatment of postoperative pain after lumbar disc surgery.
Topics: Adult; Aged; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygenase Inhibitors; Diskectomy; D | 2002 |
Comparison of the analgesic efficacy of rofecoxib and enteric-coated diclofenac sodium in the treatment of postoperative dental pain: a randomized, placebo-controlled clinical trial.
Topics: Adolescent; Adult; Anti-Inflammatory Agents, Non-Steroidal; Diclofenac; Dose-Response Relationship, | 2002 |
21 other studies available for rofecoxib and Acute Post-operative Pain
| Article | Year |
|---|---|
Stent removal need not be painful.
Topics: Cyclooxygenase 2 Inhibitors; Device Removal; Female; Humans; Lactones; Male; Pain, Postoperative; St | 2013 |
[Rofecoxib in surgical pain. Saving morphine!].
Topics: Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Humans; Lacto | 2002 |
[...bad example of a miserable "research on order"].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Data Interpretation, Statistical | 2002 |
[When dental extraction or surgical intervention is anticipated. Coxib decreases postoperative pain].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; Cyclooxygena | 2003 |
[Selective COX 2 inhibitor rofecoxib. To "defy" the pain].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthritis; Arthritis, Rheumatoid; Cyclooxygenase Inhibitors | 2003 |
[Less pain after surgical intervention. Starting analgesia already before surgery].
Topics: Anti-Inflammatory Agents, Non-Steroidal; Clinical Trials as Topic; Cyclooxygenase Inhibitors; Humans | 2003 |
COX-2 inhibitor improves pain outcomes.
Topics: Arthroplasty, Replacement, Knee; Cyclooxygenase Inhibitors; Humans; Lactones; Pain, Postoperative; S | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Results of a multimodal analgesic trial involving patients with total hip or total knee arthroplasty.
Topics: Acetaminophen; Aged; Analgesia, Patient-Controlled; Analgesics; Analgesics, Opioid; Anesthetics, Loc | 2004 |
Comment on efficacy of rofecoxib and nimesulide in controlling post-extraction pain in oral surgery: a randomised comparative study.
Topics: Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Humans; Lactones; Pa | 2004 |
[Minor rate of side-effects makes it possible. Coxibs accrue new indications].
Topics: Analgesics; Anti-Inflammatory Agents; Cyclooxygenase Inhibitors; Drug Interactions; Humans; Lactones | 2004 |
The safety of the perioperative administration of cyclooxygenase-2 inhibitors for post-surgical pain.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Arthroplasty; Blood Loss, Surgical; Celecoxib; Child; Cyclo | 2005 |
Comment on: Gilron I, Orr E, Tu D, O'Neill JP, Zamora JE, Bell AC. A placebo-controlled randomized clinical trial of perioperative administration of gabapentin, rofecoxib and their combination for spontaneous and movement-evoked pain after abdominal hyste
Topics: Adult; Amines; Antiparkinson Agents; Cyclohexanecarboxylic Acids; Cyclooxygenase Inhibitors; Data In | 2005 |
High dose nonsteroidal anti-inflammatory drugs compromise spinal fusion.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Female; Humans; Ketorolac; Lactones | 2005 |
Efficacy of the NSAIDs depends on multiple factors.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Female; Humans; Hysterectomy; La | 2005 |
Postsurgical safety of opioid-sparing cyclooxygenase-2 inhibitors.
Topics: Analgesics, Opioid; Clinical Trials as Topic; Cyclooxygenase 2 Inhibitors; Humans; Isoxazoles; Lacto | 2006 |
A new class of COX-2 inhibitors offer an alternative to NSAIDS in pain management after spinal surgery.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Celecoxib; Cyclooxygenase 2; Cyclooxygenase 2 Inhibitors; C | 2001 |
Nonsteroidal anti-inflammatory drugs for perioperative pain control.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Butanones; Celecoxib; Cyclooxygenase Inhibitors; Diclofenac | 2001 |
[Cox-2 inhibitors in the focus. Rofecoxib as effective as the "classics"].
Topics: Acetaminophen; Analgesics, Non-Narcotic; Analgesics, Opioid; Anti-Inflammatory Agents, Non-Steroidal | 2001 |
Gastrointestinal bleeds associated with rofecoxib.
Topics: Aged; Anti-Inflammatory Agents, Non-Steroidal; Cyclooxygenase Inhibitors; Gastrointestinal Hemorrhag | 2002 |
Aseptic meningitis associated with rofecoxib.
Topics: Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Arthritis, Rheumatoid; Carpal Tunn | 2002 |
Rofecoxib reduces perioperative morphine consumption for abdominal hysterectomy and laparoscopic gastric banding.
Topics: Administration, Oral; Dose-Response Relationship, Drug; Drug Interactions; Female; Gastroplasty; Hum | 2002 |