Page last updated: 2024-10-30

memantine and Acute Post-operative Pain

memantine has been researched along with Acute Post-operative Pain in 7 studies

Research Excerpts

ExcerptRelevanceReference
"In a randomized, double-blinded and cross-over study, the analgesic effect of memantine (a drug which reduces the excitability of sensitized neurons in the dorsal horn) was examined in 19 patients with chronic pain after nerve injury."9.09Memantine (a N-methyl-D-aspartate receptor antagonist) in the treatment of neuropathic pain after amputation or surgery: a randomized, double-blinded, cross-over study. ( Gottrup, H; Jensen, TS; Kristensen, AG; Nikolajsen, L, 2000)
" The administration of a higher dosage is probably not tolerable."6.71Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain--results of a randomized double-blinded, placebo-controlled trial. ( Dertwinkel, R; Hosbach, I; Maier, C; Mansourian, N; Schwenkreis, P; Senne, I; Skipka, G; Tegenthoff, M; Zenz, M, 2003)
"In a randomized, double-blinded and cross-over study, the analgesic effect of memantine (a drug which reduces the excitability of sensitized neurons in the dorsal horn) was examined in 19 patients with chronic pain after nerve injury."5.09Memantine (a N-methyl-D-aspartate receptor antagonist) in the treatment of neuropathic pain after amputation or surgery: a randomized, double-blinded, cross-over study. ( Gottrup, H; Jensen, TS; Kristensen, AG; Nikolajsen, L, 2000)
"Considering the high prevalence of breast cancer and of post-mastectomy neuropathic pain, a clinical trial is carried out to evaluate if memantine may prevent neuropathic pain development and maintain cognitive function and quality of life in cancer patients."2.79Prevention of post-mastectomy neuropathic pain with memantine: study protocol for a randomized controlled trial. ( Dubray, C; Joly, D; Morel, V; Pereira, B; Pickering, G; Roux, D; Villatte, C, 2014)
" The administration of a higher dosage is probably not tolerable."2.71Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain--results of a randomized double-blinded, placebo-controlled trial. ( Dertwinkel, R; Hosbach, I; Maier, C; Mansourian, N; Schwenkreis, P; Senne, I; Skipka, G; Tegenthoff, M; Zenz, M, 2003)
"Therefore, we examined the impact of postoperative pain on cognitive functions in aged animals."1.39Postoperative pain impairs subsequent performance on a spatial memory task via effects on N-methyl-D-aspartate receptor in aged rats. ( Chi, H; Eguchi, S; Iwata, H; Kawano, T; Kumagai, N; Takahashi, Y; Tamura, T; Yamazaki, F; Yokoyama, M, 2013)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (42.86)29.6817
2010's3 (42.86)24.3611
2020's1 (14.29)2.80

Authors

AuthorsStudies
Capuco, A1
Urits, I1
Orhurhu, V1
Chun, R1
Shukla, B1
Burke, M1
Kaye, RJ1
Garcia, AJ1
Kaye, AD1
Viswanath, O1
Chi, H1
Kawano, T1
Tamura, T1
Iwata, H1
Takahashi, Y1
Eguchi, S1
Yamazaki, F1
Kumagai, N1
Yokoyama, M1
Pickering, G2
Morel, V2
Joly, D2
Villatte, C2
Roux, D2
Dubray, C2
Pereira, B2
Durando, X1
Daulhac, L1
Coudert, C1
Suzuki, M1
Maier, C1
Dertwinkel, R1
Mansourian, N1
Hosbach, I1
Schwenkreis, P1
Senne, I1
Skipka, G1
Zenz, M1
Tegenthoff, M1
Nikolajsen, L1
Gottrup, H1
Kristensen, AG1
Jensen, TS1

Clinical Trials (4)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Evaluation of the Efficacy of Perioperative Administration of Tianeptine Versus Pregabalin on Acute and Chronic Post Mastectomy Pain After Breast Cancer Surgery. A Double-Blinded Randomized Controlled Trial.[NCT05935059]90 participants (Anticipated)Interventional2023-06-21Recruiting
Effect of Ultrasound Guided Erector Spinae Plane Block Versus Ultrasound Guided Serratus Anterior Block on the Incidence of Post Mastectomy Pain Syndrome, Randomized Double Blinded Controlled Study[NCT05201963]120 participants (Anticipated)Interventional2021-11-01Recruiting
Preventing the Development of Neuropathic Pain Post-mastectomy/Tumorectomy by Pre-emptive or Post-operative Memantine Administration[NCT01536314]Phase 343 participants (Actual)Interventional2012-02-29Completed
Efficacy of Memantine in the Treatment of Fibromyalgia: a Double-blind Randomized Trial[NCT01653457]Phase 360 participants (Anticipated)Interventional2012-09-30Not yet recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for memantine and Acute Post-operative Pain

ArticleYear
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
    Current pain and headache reports, 2020, Jun-11, Volume: 24, Issue:8

    Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres

2020
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
    Current pain and headache reports, 2020, Jun-11, Volume: 24, Issue:8

    Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres

2020
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
    Current pain and headache reports, 2020, Jun-11, Volume: 24, Issue:8

    Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres

2020
A Comprehensive Review of the Diagnosis, Treatment, and Management of Postmastectomy Pain Syndrome.
    Current pain and headache reports, 2020, Jun-11, Volume: 24, Issue:8

    Topics: Acetylcholine Release Inhibitors; Analgesics; Anesthesia, Conduction; Anesthetics, Local; Antidepres

2020
Role of N-methyl-D-aspartate receptor antagonists in postoperative pain management.
    Current opinion in anaesthesiology, 2009, Volume: 22, Issue:5

    Topics: Analgesics, Opioid; Dextromethorphan; Drug Combinations; Drug Therapy, Combination; Excitatory Amino

2009

Trials

4 trials available for memantine and Acute Post-operative Pain

ArticleYear
Prevention of post-mastectomy neuropathic pain with memantine: study protocol for a randomized controlled trial.
    Trials, 2014, Aug-20, Volume: 15

    Topics: Breast Neoplasms; Clinical Protocols; Cognition Disorders; Excitatory Amino Acid Antagonists; Female

2014
Memantine before Mastectomy Prevents Post-Surgery Pain: A Randomized, Blinded Clinical Trial in Surgical Patients.
    PloS one, 2016, Volume: 11, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Female; Humans; Mastectomy; Memantine; Middle Aged; Pain, Postoperati

2016
Efficacy of the NMDA-receptor antagonist memantine in patients with chronic phantom limb pain--results of a randomized double-blinded, placebo-controlled trial.
    Pain, 2003, Volume: 103, Issue:3

    Topics: Adult; Aged; Chronic Disease; Demography; Double-Blind Method; Excitatory Amino Acid Antagonists; Fe

2003
Memantine (a N-methyl-D-aspartate receptor antagonist) in the treatment of neuropathic pain after amputation or surgery: a randomized, double-blinded, cross-over study.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:4

    Topics: Adult; Aged; Amputation, Surgical; Amputation, Traumatic; Analgesics; Chronic Disease; Cross-Over St

2000

Other Studies

1 other study available for memantine and Acute Post-operative Pain

ArticleYear
Postoperative pain impairs subsequent performance on a spatial memory task via effects on N-methyl-D-aspartate receptor in aged rats.
    Life sciences, 2013, Dec-18, Volume: 93, Issue:25-26

    Topics: Age Factors; Amides; Anesthetics; Animals; Hippocampus; Isoflurane; Male; Maze Learning; Memantine;

2013