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baclofen and Acute Post-operative Pain

baclofen has been researched along with Acute Post-operative Pain in 14 studies

Research Excerpts

ExcerptRelevanceReference
"The purpose of this study is to describe the efficacy and adverse events of neuraxial anesthesia for post-operative pain control in non-ambulatory children with cerebral palsy with pre-existing intrathecal baclofen (ITB) pumps undergoing hip reconstructive or palliative surgery."8.12Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps. ( Ball, MA; Davids, JR; Davidson, LT; Kephart, DT; Kulkarni, VA; Tumber, S, 2022)
"A retrospective chart review was performed of patients with cerebral palsy undergoing single event, multilevel lower extremity surgery at a single institution who received epidural analgesia with or without continuous baclofen infusion."7.81Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy. ( Halanski, MA; Montero, RJ; Nemeth, BA; Noonan, KJ, 2015)
"The purpose of this study is to describe the efficacy and adverse events of neuraxial anesthesia for post-operative pain control in non-ambulatory children with cerebral palsy with pre-existing intrathecal baclofen (ITB) pumps undergoing hip reconstructive or palliative surgery."4.12Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps. ( Ball, MA; Davids, JR; Davidson, LT; Kephart, DT; Kulkarni, VA; Tumber, S, 2022)
"A retrospective chart review was performed of patients with cerebral palsy undergoing single event, multilevel lower extremity surgery at a single institution who received epidural analgesia with or without continuous baclofen infusion."3.81Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy. ( Halanski, MA; Montero, RJ; Nemeth, BA; Noonan, KJ, 2015)
"Baclofen is an agonist for a subtype of gamma-amino butyric acid (GABA-B) receptors and traditionally been used for the systemic treatment of spasticity."2.94Effect of Topical Baclofen 5% on Post-Hemorrhoidectomy Pain: Randomized Double Blind Placebo-Controlled Clinical Trial. ( Ala, S; Alvandipour, M; Mansourifar, M; Monajati, M; Saeedi, M; Shiva, A, 2020)
"Specifically, postsurgical pain continues to be a frequent and undermanaged condition."1.51Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen. ( Alewood, PF; Cheneval, O; Dekan, Z; Deuis, JR; Morgan, M; Mueller, A; Schroeder, CI; Starobova, H; Vetter, I, 2019)
"Baclofen was not statistically superior to placebo at any one of the four hourly measurements."1.27Is baclofen an analgesic? ( Fromm, GH; Potter, DM; Terrence, CF, 1983)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19903 (21.43)18.7374
1990's3 (21.43)18.2507
2000's1 (7.14)29.6817
2010's4 (28.57)24.3611
2020's3 (21.43)2.80

Authors

AuthorsStudies
Samineni, AV1
Eklund, SE1
Miller, PE1
Buxton, K1
Snyder, BD1
Matheney, TH1
Watkins, CJ1
Stone, SSD1
Alrayashi, W1
Brusseau, R1
Shore, BJ1
Kulkarni, VA1
Kephart, DT1
Ball, MA1
Tumber, S1
Davidson, LT1
Davids, JR1
Ala, S1
Alvandipour, M1
Saeedi, M1
Mansourifar, M1
Monajati, M1
Shiva, A1
Rizzo, G1
Bussolin, L1
Genitori, L1
Zicca, A1
Messeri, A1
Lenge, M1
Giordano, F1
Mueller, A1
Starobova, H1
Morgan, M1
Dekan, Z1
Cheneval, O1
Schroeder, CI1
Alewood, PF1
Deuis, JR1
Vetter, I1
Kryuchkova, SV1
Nemeth, BA1
Montero, RJ1
Halanski, MA1
Noonan, KJ1
Sanders, JC1
Gerstein, N1
Torgeson, E1
Abram, S1
Terrence, CF1
Potter, DM1
Fromm, GH1
Gordon, NC1
Gear, RW1
Heller, PH1
Paul, S1
Miaskowski, C1
Levine, JD1
Yaksh, TL1
Soliman, IE1
Park, TS1
Berkelhamer, MC1
Martin, C1
Martin, A1
Rud, C1
Valli, M1
Blumenkopf, B1

Trials

7 trials available for baclofen and Acute Post-operative Pain

ArticleYear
Effect of Topical Baclofen 5% on Post-Hemorrhoidectomy Pain: Randomized Double Blind Placebo-Controlled Clinical Trial.
    Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2020, Volume: 24, Issue:2

    Topics: Acetaminophen; Administration, Topical; Adult; Analgesics; Baclofen; Double-Blind Method; Female; GA

2020
[Efficacy of baclosan in combined therapy of muscular-tonic pain syndrome in the early postoperative period in patients after microdiscectomy].
    Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova, 2015, Volume: 115, Issue:3

    Topics: Adult; Baclofen; Combined Modality Therapy; Diskectomy; Female; Humans; Intervertebral Disc Degenera

2015
Intrathecal baclofen for postoperative analgesia after total knee arthroplasty.
    Journal of clinical anesthesia, 2009, Volume: 21, Issue:7

    Topics: Aged; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Local; Arthroplasty, Replacement, Knee; B

2009
Enhancement of morphine analgesia by the GABAB agonist baclofen.
    Neuroscience, 1995, Volume: 69, Issue:2

    Topics: Adult; Analysis of Variance; Baclofen; Double-Blind Method; Drug Therapy, Combination; Female; Human

1995
Transient paralysis after intrathecal bolus of baclofen for the treatment of post-selective dorsal rhizotomy pain in children.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:5

    Topics: Analgesics, Opioid; Baclofen; Child, Preschool; Double-Blind Method; Female; Fentanyl; GABA Agonists

1999
[Comparative study of sodium valproate and ketoprofen in the treatment of postoperative pain].
    Annales francaises d'anesthesie et de reanimation, 1988, Volume: 7, Issue:5

    Topics: Adult; Baclofen; Clinical Trials as Topic; Double-Blind Method; Female; gamma-Aminobutyric Acid; Hum

1988
Combination analgesic-antispasmodic therapy in postoperative pain.
    Spine, 1987, Volume: 12, Issue:4

    Topics: Adolescent; Adult; Aged; Baclofen; Diazepam; Drug Therapy, Combination; Female; Humans; Male; Meperi

1987

Other Studies

7 other studies available for baclofen and Acute Post-operative Pain

ArticleYear
Epidural Analgesia Versus Lumbar Plexus Blockade After Hip Reconstruction Surgery in Children With Cerebral Palsy and Intrathecal Baclofen Pumps: A Comparison of Safety and Efficacy.
    Journal of pediatric orthopedics, 2022, Apr-01, Volume: 42, Issue:4

    Topics: Analgesia, Epidural; Baclofen; Cerebral Palsy; Child; Female; Humans; Lumbosacral Plexus; Male; Pain

2022
Neuraxial anesthesia for post-operative pain control after hip surgery in children with cerebral palsy and pre-existing intrathecal baclofen pumps.
    Journal of pediatric rehabilitation medicine, 2022, Volume: 15, Issue:1

    Topics: Anesthesia; Baclofen; Cerebral Palsy; Child; Humans; Infusion Pumps, Implantable; Muscle Relaxants,

2022
The use of opioids in children receiving intrathecal baclofen therapy.
    Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery, 2019, Volume: 35, Issue:7

    Topics: Adolescent; Analgesics, Opioid; Baclofen; Child; Dystonic Disorders; Female; Humans; Injections, Spi

2019
Antiallodynic effects of the selective NaV1.7 inhibitor Pn3a in a mouse model of acute postsurgical pain: evidence for analgesic synergy with opioids and baclofen.
    Pain, 2019, Volume: 160, Issue:8

    Topics: Analgesics, Opioid; Animals; Baclofen; Disease Models, Animal; Drug Synergism; GABA-B Receptor Agoni

2019
Epidural Baclofen for the Management of Postoperative Pain in Children With Cerebral Palsy.
    Journal of pediatric orthopedics, 2015, Volume: 35, Issue:6

    Topics: Adolescent; Analgesia, Epidural; Baclofen; Cerebral Palsy; Child; Child, Preschool; Female; Humans;

2015
Is baclofen an analgesic?
    Clinical neuropharmacology, 1983, Volume: 6, Issue:3

    Topics: Acetaminophen; Adult; Baclofen; Double-Blind Method; Humans; Male; Middle Aged; Pain, Postoperative;

1983
A drug has to do what a drug has to do.
    Anesthesia and analgesia, 1999, Volume: 89, Issue:5

    Topics: Analgesics; Animals; Baclofen; Child; GABA Agonists; Humans; Injections, Spinal; Pain, Postoperative

1999