pd 98059 has been researched along with Acute Post-operative Pain in 4 studies
2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one: inhibits MAP kinase kinase (MEK) activity, p42 MAPK and p44 MAPK; structure in first source
2-(2-amino-3-methoxyphenyl)chromen-4-one : A member of the class of monomethoxyflavones that is 3'-methoxyflavone bearing an additional amino substituent at position 2'.
| Excerpt | Relevance | Reference |
|---|---|---|
| "However, in the late phase of postoperative pain, ERK activation in the ACC is only required for the expression of pain-related anxiety but not mechanical hypersensitivity." | 1.37 | Biphasic activation of extracellular signal-regulated kinase in anterior cingulate cortex distinctly regulates the development of pain-related anxiety and mechanical hypersensitivity in rats after incision. ( Dai, RP; Li, CQ; Li, F; Shi, XD; Zhang, JW; Zhang, JY; Zhou, XF, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 4 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| van den Heuvel, I | 1 |
| Reichl, S | 2 |
| Segelcke, D | 2 |
| Zahn, PK | 2 |
| Pogatzki-Zahn, EM | 2 |
| Keller, V | 1 |
| Jonas, R | 1 |
| Boecker, A | 1 |
| Wenk, M | 1 |
| Evers, D | 1 |
| Dai, RP | 1 |
| Li, CQ | 1 |
| Zhang, JW | 1 |
| Li, F | 1 |
| Shi, XD | 1 |
| Zhang, JY | 1 |
| Zhou, XF | 1 |
| Chen, G | 1 |
| Tanabe, K | 1 |
| Yanagidate, F | 1 |
| Kawasaki, Y | 1 |
| Zhang, L | 1 |
| Dohi, S | 1 |
| Iida, H | 1 |
4 other studies available for pd 98059 and Acute Post-operative Pain
| Article | Year |
|---|---|
Selective prevention of mechanical hyperalgesia after incision by spinal ERK1/2 inhibition.
Topics: Animals; Flavonoids; Hyperalgesia; Male; MAP Kinase Signaling System; Mitogen-Activated Protein Kina | 2015 |
Activation of glial glutamate transporter via MAPK p38 prevents enhanced and long-lasting non-evoked resting pain after surgical incision in rats.
Topics: Action Potentials; Animals; Aspartic Acid; Disease Models, Animal; Enzyme Inhibitors; Excitatory Ami | 2016 |
Biphasic activation of extracellular signal-regulated kinase in anterior cingulate cortex distinctly regulates the development of pain-related anxiety and mechanical hypersensitivity in rats after incision.
Topics: Animals; Anxiety; Behavior, Animal; Blotting, Western; Butadienes; Enzyme Activation; Enzyme Inhibit | 2011 |
Intrathecal endothelin-1 has antinociceptive effects in rat model of postoperative pain.
Topics: Analgesics; Animals; Behavior, Animal; Disease Models, Animal; Endothelin-1; Extracellular Signal-Re | 2012 |