clomipramine has been researched along with Acne Vulgaris in 1 studies
Clomipramine: A tricyclic antidepressant similar to IMIPRAMINE that selectively inhibits the uptake of serotonin in the brain. It is readily absorbed from the gastrointestinal tract and demethylated in the liver to form its primary active metabolite, desmethylclomipramine.
clomipramine : A dibenzoazepine that is 10,11-dihydro-5H-dibenzo[b,f]azepine which is substituted by chlorine at position 3 and in which the hydrogen attached to the nitrogen is replaced by a 3-(dimethylamino)propyl group. One of the more sedating tricyclic antidepressants, it is used as the hydrochloride salt for the treatment of depression as well as obsessive-compulsive disorder and phobias.
Acne Vulgaris: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Erythromycin would inhibit demethylation of clomipramine at the 1A2 isoenzyme and lead to a dual interaction between risperidone and clomipramine at the CYP2D6 isoenzyme." | 1.29 | Erythromycin interaction with risperidone or clomipramine in an adolescent. ( Diaz, P; Fisman, S; Reniers, D, 1996) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fisman, S | 1 |
| Reniers, D | 1 |
| Diaz, P | 1 |
1 other study available for clomipramine and Acne Vulgaris
| Article | Year |
|---|---|
Erythromycin interaction with risperidone or clomipramine in an adolescent.
Topics: Acne Vulgaris; Adolescent; Clomipramine; Cytochrome P-450 CYP1A2; Cytochrome P-450 CYP2D6; Erythromy | 1996 |