Page last updated: 2024-10-30

lauric acid and Acne Vulgaris

lauric acid has been researched along with Acne Vulgaris in 8 studies

dodecanoic acid : A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.

Acne Vulgaris: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.

Research Excerpts

ExcerptRelevanceReference
"This study aims to develop a pharmaceutical formulation that combines the potent antibacterial effect of lincomycin and lauric acid against Cutibacterium acnes (C."8.31Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation. ( Abdelhamed, FM; Abdeltawab, NF; AbouSamra, MM; Emam, KAF; Farouk, F; Salama, AH, 2023)
"This study evaluated the antimicrobial activity of lauric acid (LA) and its liposomal derivatives against Propionibacterium acnes (P."7.75The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes. ( Carson, D; Chan, M; Huang, CM; Nakatsuji, T; Pornpattananangkul, D; Yang, D; Zhang, L, 2009)
"Acne vulgaris is a chronic inflammatory skin disease that mostly develops during adolescence and continues throughout adulthood."6.94A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris. ( Akyol, M; Guner, RY; Kozan, A, 2020)
"acnes is the most sensitive to lauric acid among these bacteria."5.35Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. ( Fang, JY; Gallo, RL; Huang, CM; Kao, MC; Nakatsuji, T; Zhang, L; Zouboulis, CC, 2009)
" Our results highlight the potential of using vehicles containing lauric acid and curcumin as an alternative treatment for acne vulgaris."3.79In vitro anti-propionibacterium activity by curcumin containing vesicle system. ( Huang, HY; Liu, CH, 2013)
"This study evaluated the antimicrobial activity of lauric acid (LA) and its liposomal derivatives against Propionibacterium acnes (P."3.75The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes. ( Carson, D; Chan, M; Huang, CM; Nakatsuji, T; Pornpattananangkul, D; Yang, D; Zhang, L, 2009)
"acnes is the most sensitive to lauric acid among these bacteria."1.35Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris. ( Fang, JY; Gallo, RL; Huang, CM; Kao, MC; Nakatsuji, T; Zhang, L; Zouboulis, CC, 2009)

Research

Studies (8)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (12.50)18.2507
2000's2 (25.00)29.6817
2010's3 (37.50)24.3611
2020's2 (25.00)2.80

Authors

AuthorsStudies
Kubo, I1
Muroi, H1
Kubo, A1
AbouSamra, MM1
Farouk, F1
Abdelhamed, FM1
Emam, KAF1
Abdeltawab, NF1
Salama, AH1
Kozan, A1
Guner, RY1
Akyol, M1
Liu, CH1
Huang, HY1
Silva, EL1
Carneiro, G1
De Araújo, LA1
Trindade, Mde J1
Yoshida, MI1
Oréfice, RL1
Farias, Lde M1
De Carvalho, MA1
Dos Santos, SG1
Goulart, GA1
Alves, RJ1
Ferreira, LA1
Nakatsuji, T3
Kao, MC2
Fang, JY1
Zouboulis, CC2
Zhang, L3
Gallo, RL2
Huang, CM3
Yang, D1
Pornpattananangkul, D1
Chan, M1
Carson, D1

Trials

1 trial available for lauric acid and Acne Vulgaris

ArticleYear
A retrospective assessment and comparison of the effectiveness of benzoyl peroxide; the combination of topical niacinamide, gallic acid, and lauric acid; and the combination of benzoyl peroxide and erythromycin in acne vulgaris.
    Dermatologic therapy, 2020, Volume: 33, Issue:4

    Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Benzoyl Peroxide; Dermatologic Agents; Eryt

2020

Other Studies

7 other studies available for lauric acid and Acne Vulgaris

ArticleYear
Naturally occurring antiacne agents.
    Journal of natural products, 1994, Volume: 57, Issue:1

    Topics: Acne Vulgaris; Anti-Bacterial Agents; Fatty Alcohols; Membrane Fluidity; Microbial Sensitivity Tests

1994
Synergistic approach for acne vulgaris treatment using glycerosomes loaded with lincomycin and lauric acid: Formulation, in silico, in vitro, LC-MS/MS skin deposition assay and in vivo evaluation.
    International journal of pharmaceutics, 2023, Nov-05, Volume: 646

    Topics: Acne Vulgaris; Animals; Anti-Bacterial Agents; Cholesterol; Chromatography, Liquid; Hydrogels; Linco

2023
In vitro anti-propionibacterium activity by curcumin containing vesicle system.
    Chemical & pharmaceutical bulletin, 2013, Volume: 61, Issue:4

    Topics: Acne Vulgaris; Animals; Anti-Bacterial Agents; Curcumin; Humans; Lauric Acids; Liposomes; Particle S

2013
Solid Lipid Nanoparticles Loaded with Retinoic Acid and Lauric Acid as an Alternative for Topical Treatment of Acne Vulgaris.
    Journal of nanoscience and nanotechnology, 2015, Volume: 15, Issue:1

    Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Drug Stability; Lauric Acids; Microbi

2015
Antimicrobial property of lauric acid against Propionibacterium acnes: its therapeutic potential for inflammatory acne vulgaris.
    The Journal of investigative dermatology, 2009, Volume: 129, Issue:10

    Topics: Acne Vulgaris; Animals; Anti-Infective Agents; Benzoyl Peroxide; Cell Line; Dermatologic Agents; Dis

2009
The antimicrobial activity of liposomal lauric acids against Propionibacterium acnes.
    Biomaterials, 2009, Volume: 30, Issue:30

    Topics: Acne Vulgaris; Anti-Infective Agents; Coconut Oil; Dose-Response Relationship, Drug; Drug Delivery S

2009
Sebum free fatty acids enhance the innate immune defense of human sebocytes by upregulating beta-defensin-2 expression.
    The Journal of investigative dermatology, 2010, Volume: 130, Issue:4

    Topics: Acne Vulgaris; Animals; beta-Defensins; CD36 Antigens; Cell Line, Transformed; Fatty Acids, Nonester

2010