technetium-tc-99m-medronate and Acne-Vulgaris

We report about an 18-year-old man, suffering from acne on his face and trunk and complaining about indefinite bone pains--without any trauma. SAPHO-syndrome was diagnosed which consists of synovitis, acne, pustulosis, hyperostosis and osteitis. Five types of this syndrome can be differentiated: spondarthritis hyperostotica pustulo-psoriatica, chronic recurrent multifocal osteomyelitis, inflammatory chest wall syndrome, isolated sternocostoclavicular hyperostosis, and the combined form of acne-associated spondarthritis and chronic recurrent osteomyelitis. Although the sapho-syndrome is very rare, it should be considered a possible diagnosis in the case of indefinite bone pains in combination with acne, pustulosis and hyperostosis.

Topics: Acne Vulgaris; Acquired Hyperostosis Syndrome; Adolescent; Arthralgia; Clavicle; Diagnosis, Differential; Humans; Male; Radionuclide Imaging; Sternum; Technetium Tc 99m Medronate

Intense Tc-99m MDP uptake in both clavicles was noted in a patient with fulminant acne. X-ray examination and biopsy performed later showed hyperostosis.

Topics: Acne Vulgaris; Adolescent; Bone Diseases; Clavicle; Humans; Male; Radionuclide Imaging; Technetium Tc 99m Medronate

Topics: Acne Vulgaris; Adolescent; Arthritis, Rheumatoid; Body Weight; Diphosphonates; Fever; Humans; Male; Radiography; Radionuclide Imaging; Sacroiliac Joint; Syndrome; Technetium; Technetium Tc 99m Medronate