cimetidine has been researched along with Acne Vulgaris in 10 studies
Cimetidine: A histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS. Cimetidine has a range of pharmacological actions. It inhibits GASTRIC ACID secretion, as well as PEPSIN and GASTRIN output.
cimetidine : A member of the class of guanidines that consists of guanidine carrying a methyl substituent at position 1, a cyano group at position 2 and a 2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl group at position 3. It is a H2-receptor antagonist that inhibits the production of acid in stomach.
Acne Vulgaris: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We present first results of topically applied cimetidine in acne." | 7.67 | [Topical cimetidine treatment of acne]. ( Schmidt, JB; Spona, J, 1986) |
| "We present first results of topically applied cimetidine in acne." | 3.67 | [Topical cimetidine treatment of acne]. ( Schmidt, JB; Spona, J, 1986) |
| "Cimetidine, 1g orally per day, partially inhibited sebum excretion in patients with acne." | 3.66 | Inhibition of sebum excretion by an H2 blocker. ( Cook, J; Lyons, F; Shuster, S, 1979) |
| "Treatment with hydroxyurea and antihistamines led to resolution of the skin eruption and improvement of the pruritus." | 1.27 | Acne urticata associated with chronic myelogenous leukemia. ( Brydon, J; Duffy, T; Lucky, PA, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (90.00) | 18.7374 |
| 1990's | 1 (10.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jones, H | 1 |
| Simpson, NB | 1 |
| Blanc, D | 1 |
| Forster, RA | 1 |
| Cunliffe, WJ | 1 |
| Wilkin, JK | 1 |
| Caron, P | 2 |
| Denis, M | 1 |
| Bazex, J | 2 |
| Louvet, JP | 2 |
| Schmidt, JB | 2 |
| Lyons, F | 1 |
| Cook, J | 1 |
| Shuster, S | 1 |
| Burton, JL | 1 |
| Lovell, CR | 1 |
| Hatwal, A | 1 |
| Bhatt, RP | 1 |
| Agrawal, JK | 1 |
| Singh, G | 1 |
| Bajpai, HS | 1 |
| Spona, J | 1 |
| Chateauneuf, C | 1 |
| Brydon, J | 1 |
| Lucky, PA | 1 |
| Duffy, T | 1 |
2 trials available for cimetidine and Acne Vulgaris
| Article | Year |
|---|---|
Lack of effect of cimetidine in acne.
Topics: Acne Vulgaris; Cimetidine; Clinical Trials as Topic; Double-Blind Method; Female; Guanidines; Humans | 1980 |
Spironolactone and cimetidine in treatment of acne.
Topics: Acne Vulgaris; Adolescent; Adult; Cimetidine; Female; Humans; Male; Random Allocation; Spironolacton | 1988 |
8 other studies available for cimetidine and Acne Vulgaris
| Article | Year |
|---|---|
Cimetidine and tetracycline in acne.
Topics: Acne Vulgaris; Cimetidine; Drug Interactions; Guanidines; Humans; Tetracycline | 1982 |
[Cimetidine, new treatment of acne in women?].
Topics: Acne Vulgaris; Adult; Cimetidine; Female; Humans | 1983 |
Other antiandrogens.
Topics: Acne Vulgaris; Androgen Antagonists; Cimetidine; Female; Finasteride; Flutamide; Humans; Isotretinoi | 1998 |
Inhibition of sebum excretion by an H2 blocker.
Topics: Acne Vulgaris; Administration, Oral; Adolescent; Adult; Cimetidine; Female; Guanidines; Humans; Male | 1979 |
Cimetidine in acne.
Topics: Acne Vulgaris; Androgen Antagonists; Cimetidine; Female; Guanidines; Humans; Male; Sex Factors | 1979 |
[Topical cimetidine treatment of acne].
Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Cimetidine; Humans; Sebum | 1986 |
[Anti-seborrhea effect of cimetidine].
Topics: Acne Vulgaris; Adult; Cimetidine; Dermatitis, Seborrheic; Female; Humans; Sex Hormone-Binding Globul | 1987 |
Acne urticata associated with chronic myelogenous leukemia.
Topics: Acne Vulgaris; Cimetidine; Diphenhydramine; Female; Histamine; Humans; Hydroxyurea; Leukemia, Myeloi | 1985 |