wck-771 and Acne-Vulgaris

wck-771 has been researched along with Acne-Vulgaris* in 1 studies

Reviews

1 review(s) available for wck-771 and Acne-Vulgaris

ArticleYear
Nadifloxacin: a quinolone for topical treatment of skin infections and potential for systemic use of its active isomer, WCK 771.
    Expert opinion on pharmacotherapy, 2006, Volume: 7, Issue:14

    Nadifloxacin is a potent, broad-spectrum, quinolone agent approved for topical use in acne vulgaris and skin infections in Japan. As exposure of pathogenic and colonising bacteria to antibiotics results in drug resistance, it is not desirable to use an important, broad-spectrum antibiotic, which belongs to a class of agents widely used systemically to treat a wide variety of infections, as a topically applied preparation. On this basis, nadifloxacin is not a good option for topical treatment of acne when other effective non-antibiotic treatments are available. Nadifloxacin has potential as a topical agent for short-term treatment of skin infections. The arginine salt of its (-)-(S)-isomer is being developed as a parenteral agent based on its potency against methicillin and quinolone-resistant Staphylococcus aureus.

    Topics: Acne Vulgaris; Administration, Topical; Adolescent; Adult; Animals; Anti-Infective Agents; Clinical Trials as Topic; Fluoroquinolones; Humans; Microbial Sensitivity Tests; Quinolizines; Staphylococcal Skin Infections

2006