lactic acid has been researched along with Acne Vulgaris in 26 studies
Lactic Acid: A normal intermediate in the fermentation (oxidation, metabolism) of sugar. The concentrated form is used internally to prevent gastrointestinal fermentation. (From Stedman, 26th ed)
2-hydroxypropanoic acid : A 2-hydroxy monocarboxylic acid that is propanoic acid in which one of the alpha-hydrogens is replaced by a hydroxy group.
Acne Vulgaris: A chronic disorder of the pilosebaceous apparatus associated with an increase in sebum secretion. It is characterized by open comedones (blackheads), closed comedones (whiteheads), and pustular nodules. The cause is unknown, but heredity and age are predisposing factors.
| Excerpt | Relevance | Reference |
|---|---|---|
| "To investigate the efficacy and histologic differences of intradermal injection of a filler (poly-d, l-lactic acid, PDLA) using an MFRF device for the treatment of acne scars." | 9.51 | Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial. ( Hyeong, JH; Jung, JW; Kim, HS; Kim, KH; Seo, SB, 2022) |
| " We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin." | 9.34 | Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution." | 9.27 | Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018) |
| "Injectable poly-L-lactic acid facilitated improvement in hill and valley acne scarring and was well tolerated." | 9.20 | A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015) |
| "We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne." | 9.17 | Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study. ( Bae, BG; Chung, KY; Lee, JH; Lee, KH; Lee, SH; Lee, SJ; Lee, YS; Park, CO; Shin, H, 2013) |
| "Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities." | 9.09 | Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999) |
| "Retinoids (RC), alpha-hydroxy acids (AHA), and salicylic acid (BHA) treat acne through differing mechanisms of action." | 7.83 | Novel retinoid ester in combination with salicylic acid for the treatment of acne. ( Draelos, Z; Lewis, J; McHugh, L; Pellegrino, A; Popescu, L, 2016) |
| "This report describes a novel use of injectable poly-L-lactic acid (PLLA; Sculptra) for the correction of acne scars in an adult patient." | 7.75 | Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars. ( Palmisano, L; Sadick, NS, 2009) |
| " Minocycline is a common antibiotic used for the treatment of acne." | 7.74 | Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. ( Rison, RA; Zoraster, RM, 2008) |
| "Salicylic acid (SA) peel is a well-established peeling agent for acne." | 6.84 | Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017) |
| "To investigate the efficacy and histologic differences of intradermal injection of a filler (poly-d, l-lactic acid, PDLA) using an MFRF device for the treatment of acne scars." | 5.51 | Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial. ( Hyeong, JH; Jung, JW; Kim, HS; Kim, KH; Seo, SB, 2022) |
| "Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients." | 5.35 | Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009) |
| " We sought to determine the efficacy and safety of Jessner's solution (JS) in comparison with salicylic acid (SA) 30% in the management of acne vulgaris and postacne hyperpigmentation in patients with colored skin." | 5.34 | Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial. ( How, KN; Lim, PY; Shamsudin, N; Wan Ahmad Kammal, WSL, 2020) |
| "Acne scars may negatively impact quality of life." | 5.34 | A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. ( Beer, K, 2007) |
| "5% salicylic acid (SA) solution that does not need to be neutralized in the treatment of acne vulgaris compared to the conventional peeling using Jessner's solution." | 5.27 | Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris. ( Dong Hyun, K; Dong Ju, H; In Jae, J; Lee, HJ; Yoon, MS, 2018) |
| "Injectable poly-L-lactic acid facilitated improvement in hill and valley acne scarring and was well tolerated." | 5.20 | A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring. ( Mraud, K; Sapra, S; Schupp, R; Stewart, JA, 2015) |
| "We found that 30% salicylic acid peels were effective for inflammatory acne and more effective than Jessner's solution peels for treating noninflammatory acne." | 5.17 | Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study. ( Bae, BG; Chung, KY; Lee, JH; Lee, KH; Lee, SH; Lee, SJ; Lee, YS; Park, CO; Shin, H, 2013) |
| "Many clinicians perform glycolic acid peels for facial acne patients, but there has not been a well-controlled study to compare this new therapy with other conventional modalities." | 5.09 | Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy. ( Eun, HC; Kim, JA; Kim, SW; Moon, SE, 1999) |
| "The Jessner's-trichloroacetic acid (TCA) peel is a procedure developed by Monheit to produce a safe, effective medium-depth chemical peel for the treatment of photoaged skin, actinic keratoses, and superficial acne scars." | 4.79 | The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel. ( Monheit, GD, 1995) |
| "Retinoids (RC), alpha-hydroxy acids (AHA), and salicylic acid (BHA) treat acne through differing mechanisms of action." | 3.83 | Novel retinoid ester in combination with salicylic acid for the treatment of acne. ( Draelos, Z; Lewis, J; McHugh, L; Pellegrino, A; Popescu, L, 2016) |
| "The aim of this study was to evaluate a formulation made of poly(lactide-co-glycolide) (PLGA) nanoparticles containing azelaic acid for potential acne treatment." | 3.80 | Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment. ( Fernandes, AS; Martinho, N; Reis, CP; Roberto, A; Rosado, C, 2014) |
| "This report describes a novel use of injectable poly-L-lactic acid (PLLA; Sculptra) for the correction of acne scars in an adult patient." | 3.75 | Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars. ( Palmisano, L; Sadick, NS, 2009) |
| " Minocycline is a common antibiotic used for the treatment of acne." | 3.74 | Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy. ( Rison, RA; Zoraster, RM, 2008) |
| "Glycolic acid and Jessner's solution are popular superficial chemical peel agents for the treatment of facial acne, and increased sebum secretion is one of the major aetiological factors of acne." | 3.73 | Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients. ( Huh, CH; Lee, SH; Park, KC; Youn, SW, 2006) |
| "Salicylic acid (SA) peel is a well-established peeling agent for acne." | 2.84 | Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris. ( Amrani, A; Dayal, S; Jain, VK; Sahu, P, 2017) |
| "Acne is one of the most frequent skin disorders that occurs in puberty, but often adults also have acne." | 2.52 | [Use of organic acids in acne and skin discolorations therapy]. ( Kapuścińska, A; Nowak, I, 2015) |
| "Acne vulgaris affects up to 80% of people 11 to 30 years of age, and scarring can occur for up to 95% of these patients." | 1.35 | Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne. ( Sadove, R, 2009) |
| "Acne scars may negatively impact quality of life." | 1.34 | A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella. ( Beer, K, 2007) |
| "Multiple modalities are available for treating acne scars, one of which is chemical peeling." | 1.31 | Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals. ( Al-Sharqi, AI; Al-Waiz, MM, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (7.69) | 18.7374 |
| 1990's | 2 (7.69) | 18.2507 |
| 2000's | 7 (26.92) | 29.6817 |
| 2010's | 13 (50.00) | 24.3611 |
| 2020's | 2 (7.69) | 2.80 |
| Authors | Studies |
|---|---|
| Hyeong, JH | 3 |
| Jung, JW | 3 |
| Seo, SB | 3 |
| Kim, HS | 3 |
| Kim, KH | 3 |
| Ali, B | 1 |
| ElMahdy, N | 1 |
| Elfar, NN | 1 |
| How, KN | 1 |
| Lim, PY | 1 |
| Wan Ahmad Kammal, WSL | 1 |
| Shamsudin, N | 1 |
| In Jae, J | 1 |
| Dong Ju, H | 1 |
| Dong Hyun, K | 1 |
| Yoon, MS | 1 |
| Lee, HJ | 1 |
| Nofal, E | 1 |
| Nofal, A | 1 |
| Gharib, K | 1 |
| Nasr, M | 1 |
| Abdelshafy, A | 1 |
| Elsaid, E | 1 |
| Reis, CP | 1 |
| Martinho, N | 1 |
| Rosado, C | 1 |
| Fernandes, AS | 1 |
| Roberto, A | 1 |
| Ash, C | 1 |
| Harrison, A | 1 |
| Drew, S | 1 |
| Whittall, R | 1 |
| Kapuścińska, A | 1 |
| Nowak, I | 1 |
| Sapra, S | 1 |
| Stewart, JA | 1 |
| Mraud, K | 1 |
| Schupp, R | 1 |
| Joseph, JH | 1 |
| Draelos, Z | 1 |
| Lewis, J | 1 |
| McHugh, L | 1 |
| Pellegrino, A | 1 |
| Popescu, L | 1 |
| Dayal, S | 1 |
| Amrani, A | 1 |
| Sahu, P | 1 |
| Jain, VK | 1 |
| Sadove, R | 1 |
| Sadick, NS | 1 |
| Palmisano, L | 1 |
| Sachdeva, S | 1 |
| Bae, BG | 1 |
| Park, CO | 1 |
| Shin, H | 1 |
| Lee, SH | 2 |
| Lee, YS | 1 |
| Lee, SJ | 1 |
| Chung, KY | 1 |
| Lee, KH | 1 |
| Lee, JH | 1 |
| Monheit, G | 1 |
| Lowe, NJ | 1 |
| Huh, CH | 1 |
| Park, KC | 1 |
| Youn, SW | 1 |
| Beer, K | 1 |
| Zoraster, RM | 1 |
| Rison, RA | 1 |
| Prottey, C | 1 |
| George, D | 1 |
| Leech, RW | 1 |
| Black, JG | 1 |
| Howes, D | 1 |
| Vickers, CF | 1 |
| Monheit, GD | 1 |
| Kim, SW | 1 |
| Moon, SE | 1 |
| Kim, JA | 1 |
| Eun, HC | 1 |
| Al-Waiz, MM | 1 |
| Al-Sharqi, AI | 1 |
| Van Scott, EJ | 1 |
| Yu, RJ | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| 6 Month Double-Blind Randomized Placebo-Controlled Trial to Evaluate the Safety and Efficacy of Small Particle Hyaluronic Acid to Treat Acne Scars Located on the Cheeks and Forehead[NCT02955381] | 26 participants (Actual) | Interventional | 2017-03-28 | Terminated (stopped due to Liquidation of Research Department) | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for lactic acid and Acne Vulgaris
| Article | Year |
|---|---|
[Use of organic acids in acne and skin discolorations therapy].
Topics: Acne Vulgaris; Adolescent; Adult; Child; Dermatitis; Female; Glycolates; Gram-Positive Bacterial Inf | 2015 |
The Case for Synthetic Injectables.
Topics: Acne Vulgaris; Biocompatible Materials; Cosmetic Techniques; Dermal Fillers; Durapatite; Esthetics; | 2015 |
The Jessner's-trichloroacetic acid peel. An enhanced medium-depth chemical peel.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Drug Combinations; Ethanol; Face; Facial Dermatoses; Human | 1995 |
10 trials available for lactic acid and Acne Vulgaris
| Article | Year |
|---|---|
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Intradermal Injection of Poly-d, l-Lactic Acid Using Microneedle Fractional Radiofrequency for Acne Scars: An Open-Label Prospective Trial.
Topics: Acne Vulgaris; Cicatrix; Humans; Injections, Intradermal; Lactic Acid; Prospective Studies | 2022 |
Microneedling (Dermapen) and Jessner's solution peeling in treatment of atrophic acne scars: a comparative randomized clinical study.
Topics: Acne Vulgaris; Chemexfoliation; Cicatrix; Combined Modality Therapy; Cosmetic Techniques; Drug Combi | 2019 |
Efficacy and safety of Jessner's solution peel in comparison with salicylic acid 30% peel in the management of patients with acne vulgaris and postacne hyperpigmentation with skin of color: a randomized, double-blinded, split-face, controlled trial.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Facial Derma | 2020 |
Comparative study of buffered 50% glycolic acid (pH 3.0) + 0.5% salicylic acid solution vs Jessner's solution in patients with acne vulgaris.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Drug Combinations; Drug Therapy, Combination; Esthetics; Etha | 2018 |
Combination chemical peels are more effective than single chemical peel in treatment of mild-to-moderate acne vulgaris: A split face comparative clinical trial.
Topics: Acne Vulgaris; Adult; Analysis of Variance; Chemexfoliation; Drug Combinations; Drug Therapy, Combin | 2018 |
A randomized controlled study for the treatment of acne vulgaris using high-intensity 414 nm solid state diode arrays.
Topics: Acne Vulgaris; Adolescent; Adult; Combined Modality Therapy; Cosmetic Techniques; Double-Blind Metho | 2015 |
A Canadian study of the use of poly-L-lactic acid dermal implant for the treatment of hill and valley acne scarring.
Topics: Acne Vulgaris; Administration, Cutaneous; Adult; Biocompatible Materials; Canada; Cicatrix; Cosmetic | 2015 |
Jessner's solution vs. 30% salicylic acid peels: a comparative study of the efficacy and safety in mild-to-moderate acne vulgaris.
Topics: Acne Vulgaris; Adolescent; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Female; H | 2017 |
Salicylic acid peels versus Jessner's solution for acne vulgaris: a comparative study.
Topics: Acne Vulgaris; Adult; Chemexfoliation; Double-Blind Method; Drug Combinations; Ethanol; Face; Humans | 2013 |
Glycolic acid versus Jessner's solution: which is better for facial acne patients? A randomized prospective clinical trial of split-face model therapy.
Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe | 1999 |
13 other studies available for lactic acid and Acne Vulgaris
| Article | Year |
|---|---|
Design of polymeric nanoparticles and its applications as drug delivery systems for acne treatment.
Topics: Acne Vulgaris; Cell Survival; Chemistry, Pharmaceutical; Delayed-Action Preparations; Dicarboxylic A | 2014 |
Novel retinoid ester in combination with salicylic acid for the treatment of acne.
Topics: Acne Vulgaris; Adult; Anti-Infective Agents; Detergents; Drug Combinations; Female; Humans; Keratoly | 2016 |
Injectable poly-L: -lactic acid: a novel sculpting agent for the treatment of dermal fat atrophy after severe acne.
Topics: Acne Vulgaris; Chronic Disease; Cicatrix; Esthetics; Female; Humans; Injections, Intradermal; Lactic | 2009 |
Case study involving use of injectable poly-L-lactic acid (PLLA) for acne scars.
Topics: Acne Vulgaris; Cellulose; Cicatrix; Female; Humans; Injections, Intradermal; Lactic Acid; Mannitol; | 2009 |
Lactic acid peeling in superficial acne scarring in Indian skin.
Topics: Acne Vulgaris; Adult; Cicatrix; Female; Humans; India; Keratolytic Agents; Lactic Acid; Pilot Projec | 2010 |
Commentary: salicylic acid peels versus Jessner's solution peels for acne vulgaris: a comparative study.
Topics: Acne Vulgaris; Chemexfoliation; Drug Combinations; Ethanol; Humans; Keratolytic Agents; Lactic Acid; | 2013 |
Dispelling the myth: appropriate use of poly-L-lactic acid and clinical considerations.
Topics: Acne Vulgaris; Biodegradation, Environmental; Cicatrix; Humans; Lactic Acid; Polyesters; Polymers; P | 2006 |
Effects of repetitive superficial chemical peels on facial sebum secretion in acne patients.
Topics: Acne Vulgaris; Adolescent; Adult; Chemexfoliation; Drug Combinations; Ethanol; Facial Dermatoses; Fe | 2006 |
A single-center, open-label study on the use of injectable poly-L-lactic acid for the treatment of moderate to severe scarring from acne or varicella.
Topics: Acne Vulgaris; Adult; Biocompatible Materials; Chickenpox; Cicatrix; Cosmetic Techniques; Face; Fema | 2007 |
Severe lactic acidosis secondary to minocycline in a teenager with infectious mononucleosis and mitochondrial myopathy.
Topics: Acidosis, Lactic; Acne Vulgaris; Adolescent; Anti-Bacterial Agents; DNA, Mitochondrial; Female; Huma | 2008 |
The mode of action of ethyl lactate as a treatment for acne.
Topics: Acne Vulgaris; Adolescent; Adult; Animals; Ethanol; Female; Humans; Hydrogen-Ion Concentration; Lact | 1984 |
Medium-depth chemical peels in the treatment of acne scars in dark-skinned individuals.
Topics: Acne Vulgaris; Adolescent; Adult; Caustics; Chemexfoliation; Cicatrix; Drug Combinations; Drug Thera | 2002 |
Alpha hydroxy acids: procedures for use in clinical practice.
Topics: Acne Vulgaris; Administration, Topical; Glycolates; Humans; Ichthyosis; Keratosis; Lactates; Lactic | 1989 |