demeclocycline and Acne-Vulgaris

Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Clindamycin; Clinical Trials as Topic; Demeclocycline; Erythromycin; Fatty Acids, Nonesterified; Female; Humans; Lincomycin; Middle Aged; Placebos; Pregnancy; Propionibacterium acnes; Sulfamethoxazole; Tetracycline; Tetracyclines; Trimethoprim

Topics: Acne Vulgaris; Clindamycin; Demeclocycline; Fatty Acids; Fatty Acids, Nonesterified; Humans; Neomycin; Propionibacterium acnes; Sebum; Staphylococcus; Triglycerides

Topics: Absorption; Acne Vulgaris; Bacteria; Bacteriuria; Bronchial Diseases; Chemical and Drug Induced Liver Injury; Chemical Phenomena; Chemistry; Chlortetracycline; Demeclocycline; Drug Eruptions; Humans; Infections; Kidney Diseases; Methacycline; Oxytetracycline; Protein Binding; Tetracycline; Tooth Discoloration

Various tetracyclines and erythromycins have been used rather empirically for the systemic treatment of acne vulgaris for more than a decade. It has been impossible to accurately evaluate clinically the numerous derivatives and to compare their effectiveness with other antibiotics such as clindamycin. As a substitute for this approach, this present study ranks these antibiotics, when given orally, as to their effectivensss in suppressing the fatty acids in sebum in normal volunteers. As a group, the tetracyclines were more effective than the erythromycins in decreasing the fatty acids, but clindamycin was significantly more potent than either.

Topics: Acne Vulgaris; Anti-Bacterial Agents; Chlortetracycline; Clindamycin; Clinical Trials as Topic; Demeclocycline; Erythromycin; Esters; Fatty Acids; Humans; Minocycline; Sebum; Spectrophotometry, Infrared; Tetracycline

Topics: Acne Vulgaris; Adolescent; Adult; Anti-Bacterial Agents; Child; Clindamycin; Clinical Trials as Topic; Demeclocycline; Erythromycin; Fatty Acids, Nonesterified; Female; Humans; Lincomycin; Middle Aged; Placebos; Pregnancy; Propionibacterium acnes; Sulfamethoxazole; Tetracycline; Tetracyclines; Trimethoprim

Topics: Acne Vulgaris; Ampicillin; Anti-Bacterial Agents; Carotenoids; Clindamycin; Clinical Trials as Topic; Demeclocycline; Doxycycline; Drug Evaluation; Drug Therapy, Combination; Erythromycin; Humans; Methods; Tetracycline

Topics: Acne Vulgaris; Animals; Anura; Cyclic AMP; Demeclocycline; Diabetes Insipidus; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Osmosis; Urinary Bladder; Vasopressins

Topics: Acne Vulgaris; Administration, Topical; Anti-Bacterial Agents; Benzoyl Peroxide; Clindamycin; Demeclocycline; Erythromycin; Fatty Acids, Nonesterified; Humans; Neomycin; Novobiocin; Peroxides; Propionibacterium acnes; Skin; Triglycerides

The therapeutic value of various ultraviolet treatments was assessed in patients with moderately severe papulopustular acne. The results did not verify the common belief that ultraviolet radiation is highly beneficial. In no instance was the comedo count appreciably reduced. Modest improvement was observed with sunburn rays (UV-B) and slightly more with the combination of long ultraviolet radiation (UV-A) and UV-B. UV-A alone had the least effect. Photosensitization with coal tar and UV-A greatly aggravated acne and was notably comedogenic. Photosensitization with methoxsalen (8-methoxypsoralen) applied topically was neither harmful nor helpful.

Topics: Acne Vulgaris; Coal Tar; Demeclocycline; Humans; Methoxsalen; Photochemotherapy; Ultraviolet Therapy

Topics: Acne Vulgaris; Acute Kidney Injury; Body Weight; Chemical and Drug Induced Liver Injury; Demeclocycline; Diabetes Insipidus; Drug Eruptions; Female; Gastrointestinal Diseases; Hematologic Diseases; Humans; Infections; Photosensitivity Disorders; Pregnancy; Tetracyclines; Time Factors

Topics: Acne Vulgaris; Administration, Oral; Candidiasis, Vulvovaginal; Clindamycin; Colitis; Demeclocycline; Drug Evaluation; Erythromycin; Female; Humans; Minocycline; Photosensitivity Disorders; Tetracycline; Time Factors

Topics: Acne Vulgaris; Adult; Demeclocycline; Diabetes Insipidus; Female; Gonorrhea; Humans; Male; Polyuria; Vasopressins

Topics: Acne Vulgaris; Adolescent; Adult; Demeclocycline; Dermatitis; Drug Hypersensitivity; Female; Humans; Male; Photosensitivity Disorders; Skin; Sunburn; Time Factors

Topics: Abscess; Acne Vulgaris; Adolescent; Adult; Aged; Cellulitis; Demeclocycline; Female; Furunculosis; Humans; Male; Microbial Sensitivity Tests; Middle Aged; Skin Diseases; Staphylococcus; Tetracycline

Topics: Acne Vulgaris; Adolescent; Adult; Child; Corynebacterium; Demeclocycline; Female; Humans; Male; Middle Aged; Penicillin V; Staphylococcus; Tetracycline

Topics: Acne Vulgaris; Adolescent; Adult; Demeclocycline; Female; Humans; Male

Topics: Acne Vulgaris; Demeclocycline; Drug Therapy; Toxicology

Topics: Acne Vulgaris; Adolescent; Anti-Bacterial Agents; Demeclocycline; Drug Therapy; Humans; Placebos; Tetracycline

Topics: Acne Vulgaris; Anti-Bacterial Agents; Demeclocycline; Humans; Tetracycline; Toxicology

Topics: Acne Vulgaris; Adolescent; Biomedical Research; Child; Cysts; Demeclocycline; Exanthema; Humans; Placebos; Sebum; Skin Diseases; Vitamin A

Topics: Acne Vulgaris; Chlorpromazine; Demeclocycline; Drug Therapy; Erythromycin; Facial Dermatoses; Humans; Hyperpigmentation; Pigmentation Disorders; Radiation Effects; Radiotherapy; X-Rays