ibuprofen has been researched along with Leiomyoma in 6 studies
Midol: combination of cinnamedrine, phenacetin, aspirin & caffeine
Leiomyoma: A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the second part of the study, 24 women with excessive menstrual bleeding (13 with primary menorrhagia, 10 with uterine fibromyomas, one with haemostatic factor VIII deficiency) were treated at random with ibuprofen (600 mg/day and 1200 mg/day) and with a placebo." | 9.06 | Primary and myoma-associated menorrhagia: role of prostaglandins and effects of ibuprofen. ( Mäkäräinen, L; Ylikorkala, O, 1986) |
| " In the second part of the study, 24 women with excessive menstrual bleeding (13 with primary menorrhagia, 10 with uterine fibromyomas, one with haemostatic factor VIII deficiency) were treated at random with ibuprofen (600 mg/day and 1200 mg/day) and with a placebo." | 5.06 | Primary and myoma-associated menorrhagia: role of prostaglandins and effects of ibuprofen. ( Mäkäräinen, L; Ylikorkala, O, 1986) |
| "Ibuprofen (IBU) loaded polyvinyl alcohol-based hydrogel beads (IBU-BB) were designed to alleviate side effects such as inflammation and pain following uterine artery embolization for the treatment of leiomyomata." | 3.73 | Release of ibuprofen from beads for embolization: in vitro and in vivo studies. ( Borovac, T; Guiffant, G; Kasselouri, A; Laurent, A; Pelage, JP; Prognon, P, 2006) |
| "In the treatment of uterine fibroid embolization related pain, the use of embolics loaded with non-steroidal anti-inflammatory drugs (NSAID) relies on an efficient delivery and impregnation of the embolized tissue." | 1.37 | IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen. ( Bédouet, L; Bevilacqua, C; Laurent, A; Lewis, AL; Martin, P; Namur, J; Pelage, JP; Schwartz-Cornil, I; Verret, V; Wassef, M, 2011) |
| "Uterine leiomyomas are found in approximately 2% of pregnant women." | 1.28 | Complications of uterine leiomyomas in pregnancy. ( Dotters, DJ; Droegemeuller, W; Katz, VL, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (33.33) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Verret, V | 1 |
| Bevilacqua, C | 1 |
| Schwartz-Cornil, I | 1 |
| Pelage, JP | 2 |
| Wassef, M | 1 |
| Namur, J | 1 |
| Bédouet, L | 1 |
| Lewis, AL | 1 |
| Martin, P | 1 |
| Laurent, A | 2 |
| Pullè, C | 1 |
| Sturlese, E | 1 |
| Borovac, T | 1 |
| Kasselouri, A | 1 |
| Prognon, P | 1 |
| Guiffant, G | 1 |
| Katz, VL | 1 |
| Dotters, DJ | 1 |
| Droegemeuller, W | 1 |
| Stalnikowicz, R | 1 |
| Eliakim, R | 1 |
| Ligumsky, M | 1 |
| Rachmilewitz, D | 1 |
| Mäkäräinen, L | 1 |
| Ylikorkala, O | 1 |
2 trials available for ibuprofen and Leiomyoma
| Article | Year |
|---|---|
Clinical trial comparing the activity and efficacy of ibuprofen isobutanolammonium vs Benzydamine hydrochloride, applied as vaginal irrigations, in patients with vaginitis.
Topics: Adult; Aged; Benzydamine; Female; Humans; Ibuprofen; Leiomyoma; Middle Aged; Therapeutic Irrigation; | 2002 |
Primary and myoma-associated menorrhagia: role of prostaglandins and effects of ibuprofen.
Topics: Adult; Clinical Trials as Topic; Double-Blind Method; Endometrium; Epoprostenol; Female; Humans; Ibu | 1986 |
4 other studies available for ibuprofen and Leiomyoma
| Article | Year |
|---|---|
IL6 and TNF expression in vessels and surrounding tissues after embolization with ibuprofen-loaded beads confirms diffusion of ibuprofen.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Delayed-Action Preparations; Drug Delivery Systems | 2011 |
Release of ibuprofen from beads for embolization: in vitro and in vivo studies.
Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Chemistry, Pharmaceutical; Delayed-Action Preparat | 2006 |
Complications of uterine leiomyomas in pregnancy.
Topics: Adult; Cesarean Section; Female; Fetal Membranes, Premature Rupture; Humans; Ibuprofen; Labor Presen | 1989 |
Drug-induced bleeding of gastric leiomyoma.
Topics: Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Aspirin; Gastrointestinal Hemorrhage; Humans; | 1987 |