technetium-tc-99m-medronate and Leiomyoma

A 47-year-old woman with adenocarcinoma of the right breast had bone scintigraphy with Tc-99m MDP. Bone imaging did not show any metastases. However, a large area of increased tracer uptake was seen extending from the abdomen to the pelvis. Abdominal ultrasound revealed a large solid and heterogeneous mass, measuring 18 x 11 x 14.3 cm, that originated in an empty uterus. A biopsy of the surgical specimen showed a leiomyoma of the uterus.

Topics: Adenocarcinoma; Biopsy; Breast Neoplasms; Female; Humans; Leiomyoma; Middle Aged; Neoplasms, Multiple Primary; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Ultrasonography; Uterine Neoplasms

Topics: Adult; Bone Neoplasms; Breast Neoplasms; Diagnosis, Differential; Female; Humans; Leiomyoma; Radionuclide Imaging; Radiopharmaceuticals; Technetium Tc 99m Medronate; Tomography, X-Ray Computed; Urinary Bladder; Uterine Neoplasms

Topics: Aged; Bone and Bones; Humans; Leiomyoma; Male; Radionuclide Imaging; Stomach Neoplasms; Technetium Tc 99m Medronate

Topics: Aged; Aged, 80 and over; Diagnostic Imaging; Female; Humans; Leiomyoma; Technetium Tc 99m Medronate; Uterine Neoplasms

Bone imaging is commonly used as a sensitive indicator of metastatic bone diseases or other bone pathology. Furthermore, it is now generally known that technetium-99m (99mTc) phosphonates tend to concentrate in various tissues other than bones. Ultrasonography is also widely used for the evaluation of pelvic masses. Ultrasonography is especially useful for detecting a cystic mass. We present a case where the uptake of 99mTc phosphonate compounds occurred in the entire abdomen, and ultrasonography suggested a diagnosis of pseudomyxoma peritonei, but the condition was later proven to be degeneration of giant subserous leiomyoma of the uterus. We have found two interesting features in this case. One is the 99mTc phosphonate concentration in the large cystic and hyaline degeneration of subserous leiomyoma of the uterus without calcification, and the other is the sonographic finding of a large echogenic mass with innumerable small anechoic areas. To our knowledge, no cases of 99mTc phosphonate concentration in non-calcified leiomyoma of the uterus have been demonstrated.

Topics: Adult; Female; Humans; Leiomyoma; Radionuclide Imaging; Technetium Tc 99m Medronate; Ultrasonography; Uterine Neoplasms

Topics: Aged; Calcinosis; Female; Humans; Leiomyoma; Radionuclide Imaging; Technetium Tc 99m Medronate; Uterine Neoplasms