Page last updated: 2024-08-24

2-methoxyestradiol and Leiomyoma

2-methoxyestradiol has been researched along with Leiomyoma in 6 studies

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (33.33)29.6817
2010's2 (33.33)24.3611
2020's2 (33.33)2.80

Authors

AuthorsStudies
Borahay, MA; Bujalowski, PJ; Enazy, SA; Kilic, G; Kirschen, GW; Motamedi, M; Oberhauser, AF; Rytting, E; Saada, J; Salama, SA; Shah, M; Vincent, K; Yang, J1
Borahay, MA; Kilic, GS; Motamedi, M; Ozpolat, B; Salama, SA; Tekedereli, I; Vincent, KL1
Borahay, MA; Botting, S; Diaz-Arrastia, CR; Hamed, AA; Kamel, MW; Kilic, GS; Saeed, M; Salama, SA; Salih, SM; Williams, MY1
Diaz-Arrastia, CR; Kamel, MW; Kilic, GS; Salama, SA1
Ali, H; Kilic, G; Motamedi, M; Rytting, E; Vincent, K1
Al-Hendy, A; Dubey, RK; Nasr, AB; Salama, SA1

Other Studies

6 other study(ies) available for 2-methoxyestradiol and Leiomyoma

ArticleYear
PEGylated Polymeric Nanoparticles Loaded with 2-Methoxyestradiol for the Treatment of Uterine Leiomyoma in a Patient-Derived Xenograft Mouse Model.
    Journal of pharmaceutical sciences, 2023, Volume: 112, Issue:9

    Topics: 2-Methoxyestradiol; Animals; Estrogens; Female; Heterografts; Humans; Leiomyoma; Mercaptoethanol; Mice; Mice, Inbred NOD; Nanoparticles; Polyethylene Glycols; Polymers; Progesterone

2023
Liposomal 2-Methoxyestradiol Nanoparticles for Treatment of Uterine Leiomyoma in a Patient-Derived Xenograft Mouse Model.
    Reproductive sciences (Thousand Oaks, Calif.), 2021, Volume: 28, Issue:1

    Topics: 2-Methoxyestradiol; Animals; Antineoplastic Agents; Apoptosis; Caspase 3; Cell Proliferation; Drug Compounding; Female; Humans; Ki-67 Antigen; Leiomyoma; Liposomes; Mice, Inbred NOD; Mice, SCID; Nanoparticles; Tumor Burden; Uterine Neoplasms; Xenograft Model Antitumor Assays

2021
Catechol-o-methyltransferase expression and 2-methoxyestradiol affect microtubule dynamics and modify steroid receptor signaling in leiomyoma cells.
    PloS one, 2009, Oct-07, Volume: 4, Issue:10

    Topics: 2-Methoxyestradiol; Apoptosis; Aromatase; Catechol O-Methyltransferase; Estradiol; Estrogen Receptor alpha; Female; Humans; Leiomyoma; Microtubules; Neovascularization, Pathologic; Receptors, Progesterone; Receptors, Steroid; Signal Transduction; Tumor Necrosis Factor-alpha; Uterine Neoplasms

2009
2-Methoxyestradiol causes functional repression of transforming growth factor β3 signaling by ameliorating Smad and non-Smad signaling pathways in immortalized uterine fibroid cells.
    Fertility and sterility, 2012, Volume: 98, Issue:1

    Topics: 2-Methoxyestradiol; Cell Line, Transformed; Cell Nucleus; Down-Regulation; Drug Evaluation, Preclinical; Estradiol; Female; Fibrosis; Humans; Leiomyoma; Phosphorylation; Protein Binding; Protein Transport; Signal Transduction; Smad Proteins; Transforming Growth Factor beta3; Tubulin

2012
Nanomedicine for uterine leiomyoma therapy.
    Therapeutic delivery, 2013, Volume: 4, Issue:2

    Topics: 2-Methoxyestradiol; Calorimetry, Differential Scanning; Cell Line, Tumor; Chromatography, High Pressure Liquid; Drug Carriers; Drug Stability; Drug Storage; Estradiol; Female; Humans; Lactic Acid; Leiomyoma; Nanomedicine; Nanoparticles; Polyesters; Polyglycolic Acid; Polylactic Acid-Polyglycolic Acid Copolymer; Polymers; Time Factors; Tubulin Modulators; Uterine Neoplasms; X-Ray Diffraction

2013
Estrogen metabolite 2-methoxyestradiol induces apoptosis and inhibits cell proliferation and collagen production in rat and human leiomyoma cells: a potential medicinal treatment for uterine fibroids.
    Journal of the Society for Gynecologic Investigation, 2006, Volume: 13, Issue:8

    Topics: 2-Methoxyestradiol; Animals; Antimitotic Agents; Apoptosis; Cell Line, Tumor; Cell Proliferation; Collagen; Estradiol; Estrogens; Female; Humans; Leiomyoma; Rats; Uterine Neoplasms

2006