Page last updated: 2024-11-07

dehydroepiandrosterone and Leiomyoma

dehydroepiandrosterone has been researched along with Leiomyoma in 10 studies

Dehydroepiandrosterone: A major C19 steroid produced by the ADRENAL CORTEX. It is also produced in small quantities in the TESTIS and the OVARY. Dehydroepiandrosterone (DHEA) can be converted to TESTOSTERONE; ANDROSTENEDIONE; ESTRADIOL; and ESTRONE. Most of DHEA is sulfated (DEHYDROEPIANDROSTERONE SULFATE) before secretion.
dehydroepiandrosterone : An androstanoid that is androst-5-ene substituted by a beta-hydroxy group at position 3 and an oxo group at position 17. It is a naturally occurring steroid hormone produced by the adrenal glands.

Leiomyoma: A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.

Research Excerpts

ExcerptRelevanceReference
"The purposes of this study were to investigate the effect of a superactive agonistic analog of gonadotropin-releasing hormone, nafarelin, on uterine leiomyomas and to assess the use of magnetic resonance imaging in monitoring uterine and myoma size."7.67Use of an agonistic analog of gonadotropin-releasing hormone (nafarelin) to treat leiomyomas: assessment by magnetic resonance imaging. ( Andreyko, JL; Blumenfeld, Z; Hricak, H; Jaffe, RB; Marshall, LA; Monroe, SE, 1988)
"The purposes of this study were to investigate the effect of a superactive agonistic analog of gonadotropin-releasing hormone, nafarelin, on uterine leiomyomas and to assess the use of magnetic resonance imaging in monitoring uterine and myoma size."3.67Use of an agonistic analog of gonadotropin-releasing hormone (nafarelin) to treat leiomyomas: assessment by magnetic resonance imaging. ( Andreyko, JL; Blumenfeld, Z; Hricak, H; Jaffe, RB; Marshall, LA; Monroe, SE, 1988)
"The presence of uterine leiomyomas correlates with an increase in urinary concentrations of estrogens and androgens, and it appears to be caused by a decrease in patients' metabolism of steroids."1.32Endogenous urinary steroids in premenopausal women with uterine leiomyomas. ( Bai, SW; Chung, BC; Jung, BH, 2004)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19907 (70.00)18.7374
1990's2 (20.00)18.2507
2000's1 (10.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
GIORGI, EP1
JANATA, J1
STARKA, L1
WARREN, JC1
FRENCH, AP1
Jung, BH1
Bai, SW1
Chung, BC1
Frigo, P1
Eppel, W1
Asseryanis, E1
Sator, M1
Golaszewski, T1
Gruber, D1
Lang, C1
Huber, J1
Murphy, AA1
Kettel, LM1
Morales, AJ1
Roberts, VJ1
Yen, SS1
Andreyko, JL1
Blumenfeld, Z1
Marshall, LA1
Monroe, SE1
Hricak, H1
Jaffe, RB1
Aakvaag, A1
Fylling, P1
Miasnikov, LA1
Vinogradova, DA1
Marsiletti, GC1
Lago, E1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of Vaginal Mifepristone on Reduction of Uterine Fibroids Size and the Symptoms Associated With the Fibroids - Pilot Study (Phase IIa)[NCT00881140]Phase 230 participants (Actual)Interventional2009-04-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

1 trial available for dehydroepiandrosterone and Leiomyoma

ArticleYear
The effects of hormone substitution in depot form on the uterus in a group of 50 perimenopausal women--a vaginosonographic study.
    Maturitas, 1995, Volume: 21, Issue:3

    Topics: Dehydroepiandrosterone; Delayed-Action Preparations; Drug Combinations; Endometrium; Estradiol; Estr

1995

Other Studies

9 other studies available for dehydroepiandrosterone and Leiomyoma

ArticleYear
THE DETERMINATION OF STEROIDS IN CYST FLUID FROM HUMAN POLYCYSTIC OVARIES.
    The Journal of endocrinology, 1963, Volume: 27

    Topics: Androgens; Chromatography; Cyst Fluid; Cysts; Dehydroepiandrosterone; Endometriosis; Estradiol; Estr

1963
EFFECT OF CORTISOL ON THE PRODUCTION OF OVARIAN ANDROGENS.
    The Journal of endocrinology, 1964, Volume: 29

    Topics: 17-Ketosteroids; Adrenocorticotropic Hormone; Amenorrhea; Androgens; Biomedical Research; Dehydroepi

1964
DISTRIBUTION OF STEROID SULFATASE IN HUMAN TISSUES.
    The Journal of clinical endocrinology and metabolism, 1965, Volume: 25

    Topics: Abnormalities, Severe Teratoid; Adipose Tissue; Anencephaly; Animals; Carbon Isotopes; Cattle; Corpu

1965
Endogenous urinary steroids in premenopausal women with uterine leiomyomas.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2004, Volume: 84, Issue:1

    Topics: Adult; Androgens; Androstenols; Androsterone; Case-Control Studies; Corticosterone; Cortodoxone; Deh

2004
Regression of uterine leiomyomata in response to the antiprogesterone RU 486.
    The Journal of clinical endocrinology and metabolism, 1993, Volume: 76, Issue:2

    Topics: Adolescent; Adult; Androstenedione; Bone Density; Dehydroepiandrosterone; Dehydroepiandrosterone Sul

1993
Use of an agonistic analog of gonadotropin-releasing hormone (nafarelin) to treat leiomyomas: assessment by magnetic resonance imaging.
    American journal of obstetrics and gynecology, 1988, Volume: 158, Issue:4

    Topics: Adult; Androstenedione; Dehydroepiandrosterone; Dehydroepiandrosterone Sulfate; Drug Evaluation; Est

1988
A method for the simultaneous determination of progesterone, androstenedione, testosterone and dehydroepiandrosterone sulphate in biological fluids. Its application in the analysis of venous plasma and cyst fluid from human ovaries in situ.
    Acta endocrinologica, 1968, Volume: 57, Issue:3

    Topics: 17-Ketosteroids; Adult; Amenorrhea; Androgens; Chromatography, Gas; Dehydroepiandrosterone; Endometr

1968
[Estrogens and androgens in dyshormonal cardiopathy and coronary atherosclerosis in women].
    Kardiologiia, 1971, Volume: 11, Issue:9

    Topics: 17-Ketosteroids; Adult; Androgens; Androsterone; Arteriosclerosis; Chromatography, Thin Layer; Coron

1971
[Problems of therapy of uterine myofibroma with special reference to the hormonal and opotherapeutic opotherapeutic treatment].
    Annali di ostetricia, ginecologia, medicina perinatale, 1971, Volume: 92, Issue:12

    Topics: Age Factors; Breast; Dehydroepiandrosterone; Female; Humans; Leiomyoma; Tissue Extracts; Uterine Neo

1971