Page last updated: 2024-10-29

ipriflavone and Leiomyoma

ipriflavone has been researched along with Leiomyoma in 3 studies

ipriflavone : A member of the class of isoflavones that is isoflavone in which the hydrogen at position 7 is replaced by an isopropoxy group. A synthetic isoflavone, it was formerly used for the treatment of osteoporosis, although a randomised controlled study failed to show any benefit. It is still used to prevent osteoporosis in post-menopausal women.

Leiomyoma: A benign tumor derived from smooth muscle tissue, also known as a fibroid tumor. They rarely occur outside of the UTERUS and the GASTROINTESTINAL TRACT but can occur in the SKIN and SUBCUTANEOUS TISSUE, probably arising from the smooth muscle of small blood vessels in these tissues.

Research Excerpts

ExcerptRelevanceReference
" Ipriflavone efficaciously alleviated the adverse effects of estrogen deficiency such as bone loss and increase in LDL-C level, and the ability of leuprolide therapy to reduce myoma volume was not decreased by ipriflavone administration."2.70Efficacy of ipriflavone in preventing adverse effects of leuprolide. ( Aso, T; Chiguchi, M; Ishibashi, T; Somekawa, Y; Wakana, K, 2001)
"Uterine fibroids (also known as leiomyomas) are the most common benign pelvic tumours among women."2.52Add-back therapy with GnRH analogues for uterine fibroids. ( Brito, LG; Candido Dos Reis, FJ; Ferriani, RA; Martins, WP; Moroni, RM; Nastri, CO; Vieira, CS, 2015)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's1 (33.33)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moroni, RM1
Martins, WP1
Ferriani, RA1
Vieira, CS1
Nastri, CO1
Candido Dos Reis, FJ1
Brito, LG1
Gambacciani, M1
Cappagli, B1
Piaggesi, L1
Ciaponi, M1
Genazzani, AR1
Somekawa, Y1
Chiguchi, M1
Ishibashi, T1
Wakana, K1
Aso, T1

Reviews

1 review available for ipriflavone and Leiomyoma

ArticleYear
Add-back therapy with GnRH analogues for uterine fibroids.
    The Cochrane database of systematic reviews, 2015, Mar-20, Issue:3

    Topics: Antineoplastic Agents, Hormonal; Bone Density; Bone Density Conservation Agents; Drug Therapy, Combi

2015

Trials

2 trials available for ipriflavone and Leiomyoma

ArticleYear
Ipriflavone prevents the loss of bone mass in pharmacological menopause induced by GnRH-agonists.
    Calcified tissue international, 1997, Volume: 61 Suppl 1

    Topics: Absorptiometry, Photon; Analysis of Variance; Antineoplastic Agents, Hormonal; Bone Density; Bone Re

1997
Efficacy of ipriflavone in preventing adverse effects of leuprolide.
    The Journal of clinical endocrinology and metabolism, 2001, Volume: 86, Issue:7

    Topics: Adult; Bone Density; Cholesterol; Cholesterol, HDL; Cholesterol, LDL; Estrogen Antagonists; Female;

2001