Antral Vascular Ectasia

A distinct vascular lesion in the PYLORIC ANTRUM that is characterized by tortuous dilated blood vessels (ectasia) radiating outward from the PYLORUS. The vessel pattern resembles the stripes on the surface of a watermelon. This lesion causes both acute and chronic GASTROINTESTINAL HEMORRHAGE.

Synonym
Antral Vascular Ectasia
Gastric Antral Vascular Ectasia
Watermelon Stomach

Excerpt	Reference
"Watermelon stomach is a well-known cause of gastrointestinal bleeding and anemia."	( Bernard, G; Dumortier, J; Perreira, A; Ponchon, T; Roman, S; Saurin, JC, 2003)
"Gastric antral vascular ectasia is a rare but well-recognised cause of occult gastrointestinal bleeding."	( Buckley, MJ; McLoughlin, R; O'Morain, CA; Qasim, A; Sebastian, S, 2004)

Excerpt	Reference
"The treatment of angiodysplasia and watermelon stomach, vascular abnormalities implicated in gastrointestinal bleeding of obscure origin, is a major clinical problem."	( Balzano, T; Budillon, G; Nardone, G; Rocco, A, 1999)
"The reports of 21 patients with watermelon stomach who were treated using APC from February 1998 to August 2001 were reviewed."	( Bernard, G; Dumortier, J; Perreira, A; Ponchon, T; Roman, S; Saurin, JC, 2003)
"Patients with gastric antral vascular ectasia required a mean of 6 treatment sessions, while those with angiodysplasia required one to two sessions."	( Craig, PI; Pavey, DA, 2004)
"Patients with gastric antral vascular ectasia require significantly more treatment sessions to achieve this effect."	( Craig, PI; Pavey, DA, 2004)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	3 (4.05)	12.5806
2000's	38 (51.35)	18.1394
2010's	25 (33.78)	28.8240
2020's	8 (10.81)	9.53

Drug	Relationship Strength	Studies
nitrous oxide	low	1
busulfan	low	2
cyproheptadine	low	1
lansoprazole	low	1
thalidomide	low	3
tranexamic acid	low	4
norethindrone acetate	low	1
ethinyl estradiol	low	2
norethindrone	low	2
methylprednisolone	low	1
thiazoles	low	1
enbucrilate	low	2
neodymium	low	1
thulium	low	1
argon	low	16
ferrous sulfate	low	1
glucaric acid	low	1
imatinib mesylate	low	6
naproxen	low	1
cocaine	low	1
s 1033	low	1
polidocanol	low	2
dasatinib	low	1
alprostadil	low	1
cholecalciferol	low	1
losartan potassium	low	1
gastrins	low	3
glucagon	low	1
warfarin	low	1
ferric oxide, saccharated	low	1
folic acid	low	1

Protein Targets (944)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
TDP1 protein	11	0	0	11
AR protein	15	0	0	15
glucocorticoid receptor [Homo sapiens]	12	0	0	12
estrogen nuclear receptor alpha	16	0	0	16
peroxisome proliferator activated receptor gamma	8	0	0	8
ATP-binding cassette sub-family C member 3	0	8	0	8
Multidrug resistance-associated protein 4	0	8	0	10
Bile salt export pump	0	12	0	12
Cellular tumor antigen p53	8	0	0	8
Thromboxane-A synthase	0	1	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostacyclin receptor	0	1	1	2
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Canalicular multispecific organic anion transporter 1	0	7	0	7
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier organic anion transporter family member 2B1	0	1	0	1
Solute carrier organic anion transporter family member 3A1	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	2	0	0	2
Chain A, 2-oxoglutarate Oxygenase	4	0	0	4
15-lipoxygenase, partial	3	0	0	3
apical membrane antigen 1, AMA1	2	0	0	2
aldehyde dehydrogenase 1 family, member A1	7	0	0	7
thyroid stimulating hormone receptor	6	0	0	6
cytochrome P450 family 3 subfamily A polypeptide 4	8	0	0	8
EWS/FLI fusion protein	7	0	0	7
retinoic acid nuclear receptor alpha variant 1	9	0	0	9
retinoid X nuclear receptor alpha	11	0	0	11
estrogen-related nuclear receptor alpha	12	0	0	12
pregnane X nuclear receptor	10	0	0	10
aryl hydrocarbon receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	3	0	0	3
thyroid hormone receptor beta isoform 2	10	0	0	10
ubiquitin carboxyl-terminal hydrolase 2 isoform a	1	0	0	1
nuclear factor erythroid 2-related factor 2 isoform 1	9	0	0	9
geminin	10	0	0	10
lethal factor (plasmid)	2	0	0	2
lamin isoform A-delta10	4	0	0	4
Matrix metalloproteinase-9	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	1	0	0	1
Chain A, HADH2 protein	5	0	0	5
Chain B, HADH2 protein	5	0	0	5
Chain A, Ferritin light chain	3	0	0	3
Chain A, Cruzipain	1	0	0	1
Luciferase	5	0	0	5
interleukin 8	2	0	0	2
USP1 protein, partial	5	0	0	5
Microtubule-associated protein tau	4	0	0	4
farnesoid X nuclear receptor	8	0	0	8
peroxisome proliferator-activated receptor delta	3	0	0	3
vitamin D (1,25- dihydroxyvitamin D3) receptor	6	0	0	6
euchromatic histone-lysine N-methyltransferase 2	4	0	0	4
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	3	0	0	3
vitamin D3 receptor isoform VDRA	3	0	0	3
thyroid hormone receptor beta isoform a	5	0	0	5
nuclear receptor ROR-gamma isoform 1	4	0	0	4
DNA polymerase kappa isoform 1	1	0	0	1
survival motor neuron protein isoform d	1	0	0	1
cytochrome P450 3A4 isoform 1	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	3	0	0	3
60 kDa chaperonin	0	1	0	1
60 kDa heat shock protein, mitochondrial	0	1	0	1
Vitamin D3 receptor	0	1	1	4
Gamma-aminobutyric acid receptor subunit beta-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit delta	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	3	0	0	3
Glycine receptor subunit alpha-1	0	0	1	1
Gamma-aminobutyric acid receptor subunit gamma-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	3	0	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	3	0	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	3	0	0	3
Vitamin D3 receptor	0	0	1	1
Nuclear receptor ROR-gamma	2	0	0	2
10 kDa heat shock protein, mitochondrial	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-3	3	0	0	3
Gamma-aminobutyric acid receptor subunit beta-2	3	0	0	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
GABA theta subunit	3	0	0	3
Gamma-aminobutyric acid receptor subunit epsilon	3	0	0	3
Chain A, CHIMERA OF IG KAPPA CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain B, CHIMERA OF IG GAMMA-1 CHAIN: HUMAN CONSTANT REGION AND MOUSE VARIABLE REGION	0	0	1	1
Chain H, Fab M82G2, Heavy chain	0	0	1	1
Chain L, Fab M82G2, Light chain	0	0	1	1
Chain H, Fab M82g2, Heavy Chain	0	0	1	1
Chain L, Fab M82g2, Light Chain	0	0	1	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Amyloid-beta precursor protein	1	1	0	2
Fatty acid-binding protein, heart	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
5-hydroxytryptamine receptor 2C	0	3	0	3
Tryptophan 5-hydroxylase 1	0	1	0	1
5-hydroxytryptamine receptor 2A	0	4	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
D	0	2	0	2
5-hydroxytryptamine receptor 1A	0	3	0	3
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Liver carboxylesterase 1	0	0	0	1
Sodium-dependent noradrenaline transporter	0	6	0	6
Sodium-dependent dopamine transporter	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
5-hydroxytryptamine receptor 1B	0	3	0	3
5-hydroxytryptamine receptor 1D	0	1	0	1
5-hydroxytryptamine receptor 1F	0	1	0	1
5-hydroxytryptamine receptor 2B	0	3	0	3
5-hydroxytryptamine receptor 6	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Sodium-dependent serotonin transporter	0	7	0	7
Sodium-dependent serotonin transporter	0	2	0	3
5-hydroxytryptamine receptor 7	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
Glutamate receptor ionotropic, NMDA 1	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
Lysosomal Pro-X carboxypeptidase	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
D(2) dopamine receptor	0	3	0	3
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	0	1	0	1
Glutamate receptor ionotropic, NMDA 2B	0	1	0	1
Glutamate receptor ionotropic, NMDA 2C	0	1	0	1
Sodium-dependent dopamine transporter	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	2	0	2
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	2	0	2
Potassium voltage-gated channel subfamily H member 2	0	5	0	5
Leukotriene B4 receptor 1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Sodium-dependent dopamine transporter	0	2	0	2
Glutamate receptor ionotropic, NMDA 2D	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Glutamate receptor ionotropic, NMDA 3B	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Leukotriene B4 receptor 2	0	1	0	1
Glutamate receptor ionotropic, NMDA 3A	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Transporter	0	3	0	3
phosphopantetheinyl transferase	3	0	0	3
ATAD5 protein, partial	2	0	0	2
Fumarate hydratase	4	0	0	4
PPM1D protein	5	0	0	5
GLI family zinc finger 3	11	0	0	11
nuclear receptor subfamily 1, group I, member 3	7	0	0	7
regulator of G-protein signaling 4	2	0	0	2
cytochrome P450 2D6	5	0	0	5
polyprotein	4	0	0	4
v-jun sarcoma virus 17 oncogene homolog (avian)	3	0	0	3
cytochrome P450 2D6 isoform 1	2	0	0	2
cellular tumor antigen p53 isoform a	1	0	0	1
cytochrome P450 2C19 precursor	2	0	0	2
D(1A) dopamine receptor	1	0	0	1
chromobox protein homolog 1	3	0	0	3
potassium voltage-gated channel subfamily H member 2 isoform d	2	0	0	2
huntingtin isoform 2	3	0	0	3
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	3	0	0	3
peripheral myelin protein 22	5	0	0	5
histone acetyltransferase KAT2A isoform 1	2	0	0	2
muscarinic acetylcholine receptor M1	2	0	0	2
chaperonin GroEL	1	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15B	2	0	0	2
Sodium-dependent noradrenaline transporter	0	1	0	1
5-hydroxytryptamine receptor 4	0	2	0	2
Voltage-dependent calcium channel gamma-2 subunit	7	0	0	7
Interferon beta	8	0	0	8
Prostaglandin G/H synthase 1	0	3	0	3
Aldo-keto reductase family 1 member B1	0	4	0	4
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Muscarinic acetylcholine receptor M2	0	1	0	1
Glycogen phosphorylase, brain form	0	1	2	3
Glycogen phosphorylase, muscle form	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
D(2) dopamine receptor	0	2	0	2
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
D(3) dopamine receptor	0	1	0	1
Glutamate receptor 2	7	0	0	7
Muscarinic acetylcholine receptor M3	0	2	0	2
Endothelin receptor type B	0	1	0	1
D(1A) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A4	0	0	0	1
Endothelin receptor type B	0	1	0	1
Histamine H2 receptor	0	2	0	2
Alpha-1D adrenergic receptor	0	2	0	2
D(1B) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
D(4) dopamine receptor	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Histamine H1 receptor	0	2	1	3
D(3) dopamine receptor	0	2	0	2
UDP-glucuronosyltransferase 1A3	0	0	0	1
5-hydroxytryptamine receptor 2B	0	2	0	2
Histamine H2 receptor	2	0	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
Spike glycoprotein	5	0	1	6
D(2) dopamine receptor	0	1	0	1
Sodium-dependent serotonin transporter	0	1	0	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
Histone-lysine N-methyltransferase SETD7	0	2	0	2
Ataxin-2	7	0	0	7
Leukotriene C4 synthase	0	0	2	2
acetylcholinesterase	3	0	0	3
RAR-related orphan receptor gamma	7	0	0	7
GALC protein	1	0	0	1
GLS protein	2	0	0	2
Smad3	2	0	0	2
caspase 7, apoptosis-related cysteine protease	3	0	0	3
estrogen receptor 2 (ER beta)	6	0	0	6
progesterone receptor	8	0	0	8
67.9K protein	2	0	0	2
caspase-3	3	0	0	3
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	8	0	0	8
thyroid stimulating hormone receptor	5	0	0	5
nuclear receptor subfamily 1, group I, member 2	4	0	0	4
Histone H2A.x	2	0	0	2
Spike glycoprotein	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	2	2
Membrane-associated progesterone receptor component 1	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	1	2	3
Serine/threonine-protein kinase PLK4	0	0	2	2
Serine/threonine-protein kinase 25	0	0	2	2
ATP-dependent RNA helicase DDX3X	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	2	2
Pyridoxal kinase	0	0	2	2
Citron Rho-interacting kinase	0	0	2	2
Serine/threonine-protein kinase RIO3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 7	0	0	2	2
Serine/threonine-protein kinase Chk1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	2	3
Peripheral plasma membrane protein CASK	0	0	2	2
Aurora kinase A	0	1	2	3
Cyclin-G-associated kinase	0	0	2	2
Serine/threonine-protein kinase DCLK1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	2	3
Muscle, skeletal receptor tyrosine-protein kinase	0	0	2	2
Ephrin type-B receptor 6	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 3	0	0	2	2
Mitogen-activated protein kinase 13	0	1	2	3
Transmembrane protease serine 2	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 13	0	0	2	2
Death-associated protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 7	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 2	0	2	2	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	2	2
NUAK family SNF1-like kinase 1	0	0	2	2
Dynamin-like 120 kDa protein, mitochondrial	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	2	2
Tyrosine-protein kinase JAK2	0	0	2	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	2	0	2
Eukaryotic translation initiation factor 5B	0	0	2	2
Rho-associated protein kinase 2	0	0	2	2
Serine/threonine-protein kinase ULK1	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	2	2
Ribosomal protein S6 kinase alpha-5	0	0	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	2	2
Ribosomal protein S6 kinase alpha-4	0	0	2	2
Serine/threonine-protein kinase 16	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	2	2
Serine/threonine-protein kinase PAK 3	0	0	2	2
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	2	2
Serine/threonine-protein kinase 10	0	0	2	2
Serine/threonine-protein kinase D3	0	0	2	2
Cyclin-dependent kinase 14	0	0	2	2
Structural maintenance of chromosomes protein 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase OSR1	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	2	2
Serine/threonine-protein kinase LATS1	0	0	2	2
Serine/threonine-protein kinase PAK 4	0	0	2	2
Serine/threonine-protein kinase Chk2	0	0	2	2
Tyrosine-protein kinase ABL1	0	6	4	11
Tyrosine-protein kinase ABL1	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	1	2	3
Epidermal growth factor receptor	0	1	2	3
Transthyretin	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	2	4
Receptor tyrosine-protein kinase erbB-2	0	1	2	3
High affinity nerve growth factor receptor	0	0	2	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	1	1
ADP/ATP translocase 2	0	0	2	2
Cytochrome P450 1A2	0	1	0	1
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Protein kinase C beta type	0	0	2	2
Insulin receptor	0	1	2	3
Tyrosine-protein kinase Lck	0	5	2	7
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Tyrosine-protein kinase Fyn	0	2	2	4
Cyclin-dependent kinase 1	0	0	2	2
Glycogen phosphorylase, liver form	0	0	2	2
Tyrosine-protein kinase Fes/Fps	0	0	2	2
Macrophage colony-stimulating factor 1 receptor	0	3	2	5
Procathepsin L	0	0	1	1
Adenine phosphoribosyltransferase	0	0	1	1
Tyrosine-protein kinase Yes	0	1	2	3
Tyrosine-protein kinase Lyn	0	2	2	4
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	2	3
Insulin-like growth factor 1 receptor	0	1	2	3
Signal recognition particle receptor subunit alpha	0	0	2	2
Cytochrome c1, heme protein, mitochondrial	0	0	2	2
Hepatocyte growth factor receptor	0	0	2	2
Tyrosine-protein kinase HCK	0	3	2	5
Proto-oncogene tyrosine-protein kinase ROS	0	0	2	2
Platelet-derived growth factor receptor beta	0	3	2	5
Tyrosine-protein kinase Fgr	0	0	2	2
Quinolone resistance protein NorA	0	1	0	1
Wee1-like protein kinase 2	0	0	2	2
Uncharacterized serine/threonine-protein kinase SBK3	0	0	2	2
Replicase polyprotein 1a	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	0	1	1
Replicase polyprotein 1ab	0	1	1	2
Serine/threonine-protein kinase A-Raf	0	0	2	2
Cytochrome P450 2D6	0	2	0	2
Mast/stem cell growth factor receptor Kit	0	3	3	6
Breakpoint cluster region protein	0	4	4	9
Serine/threonine-protein kinase pim-1	0	0	2	2
Fibroblast growth factor receptor 1	0	1	2	3
Cytochrome P450 2A6	0	1	0	1
Cytochrome P450 2C9	0	4	0	4
Myosin light chain kinase, smooth muscle	0	0	1	1
Cyclin-dependent kinase 4	0	0	2	2
ADP/ATP translocase 3	0	0	2	2
Inosine-5'-monophosphate dehydrogenase 2	0	0	2	2
Angiotensin-converting enzyme	0	1	0	1
Proto-oncogene tyrosine-protein kinase Src	0	5	2	7
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	2	2
Insulin receptor-related protein	0	0	2	2
Serine/threonine-protein kinase B-raf	0	0	2	2
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	2	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	2	3
Platelet-derived growth factor receptor alpha	0	4	3	7
Tyrosine-protein kinase Blk	0	1	0	1
Tyrosine-protein kinase Fer	0	0	2	2
Protein kinase C alpha type	0	1	2	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	2	2
Vascular endothelial growth factor receptor 1	0	0	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	2	2
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	2	2
Casein kinase II subunit alpha'	0	0	2	2
Ras-related protein Rab-6A	0	0	2	2
Serine/threonine-protein kinase MAK	0	0	2	2
Cytochrome P450 2B6	0	2	0	2
Cyclin-dependent kinase 11B	0	0	2	2
Ephrin type-A receptor 1	0	0	2	2
Fibroblast growth factor receptor 2	0	0	2	2
Receptor tyrosine-protein kinase erbB-3	0	0	2	2
Multifunctional protein ADE2	0	0	2	2
Fibroblast growth factor receptor 4	0	0	2	2
Fibroblast growth factor receptor 3	0	0	2	2
cAMP-dependent protein kinase catalytic subunit gamma	0	0	2	2
cAMP-dependent protein kinase catalytic subunit beta	0	0	2	2
Ferrochelatase, mitochondrial	0	0	2	2
Ribosomal protein S6 kinase beta-1	0	0	2	2
Tyrosine-protein kinase JAK1	0	0	2	2
Protein kinase C eta type	0	0	2	2
Cyclin-dependent kinase 2	0	1	2	3
Beta-adrenergic receptor kinase 1	0	0	2	2
Probable ATP-dependent RNA helicase DDX6	0	0	2	2
Activin receptor type-2A	0	0	2	2
Mitogen-activated protein kinase 3	0	0	2	2
MAP/microtubule affinity-regulating kinase 3	0	0	2	2
Deoxycytidine kinase	0	0	2	2
Mitogen-activated protein kinase 1	0	0	2	2
Ephrin type-A receptor 2	0	2	2	4
Ephrin type-A receptor 3	0	0	2	2
Ephrin type-A receptor 8	0	0	2	2
Ephrin type-B receptor 2	0	1	2	3
Leukocyte tyrosine kinase receptor	0	0	2	2
Non-receptor tyrosine-protein kinase TYK2	0	0	2	2
UMP-CMP kinase	0	0	2	2
Phosphatidylethanolamine-binding protein 1	0	0	2	2
Wee1-like protein kinase	0	0	2	2
Heme oxygenase 2	0	0	2	2
Tyrosine-protein kinase receptor UFO	0	0	2	2
Mitogen-activated protein kinase 4	0	0	2	2
S-adenosylmethionine synthase isoform type-2	0	0	2	2
DnaJ homolog subfamily A member 1	0	0	2	2
RAC-alpha serine/threonine-protein kinase	0	1	2	3
RAC-beta serine/threonine-protein kinase	0	1	2	3
G protein-coupled receptor kinase 4	0	0	2	2
Cytochrome P450 2C19	0	3	0	3
Dual specificity protein kinase TTK	0	0	2	2
DNA replication licensing factor MCM4	0	0	2	2
Prostaglandin G/H synthase 2	0	1	2	3
Tyrosine-protein kinase receptor Tie-1	0	0	2	2
Vascular endothelial growth factor receptor 3	0	0	2	2
Vascular endothelial growth factor receptor 2	0	1	2	3
Dual specificity mitogen-activated protein kinase kinase 2	0	1	2	3
Receptor-type tyrosine-protein kinase FLT3	0	2	2	4
Bone morphogenetic protein receptor type-1A	0	0	2	2
Activin receptor type-1B	0	0	2	2
TGF-beta receptor type-1	0	0	2	2
Serine/threonine-protein kinase receptor R3	0	0	2	2
TGF-beta receptor type-2	0	0	2	2
Electron transfer flavoprotein subunit beta	0	0	1	1
Tyrosine-protein kinase CSK	0	1	2	3
Glycine--tRNA ligase	0	0	2	2
Protein kinase C iota type	0	0	2	2
Exosome RNA helicase MTR4	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	2	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	1	2	3
Serine/threonine-protein kinase mTOR	0	1	2	3
Megakaryocyte-associated tyrosine-protein kinase	0	0	2	2
Tyrosine-protein kinase Tec	0	1	2	3
Tyrosine-protein kinase TXK	0	1	2	3
Tyrosine-protein kinase ABL2	0	0	2	2
Tyrosine-protein kinase FRK	0	0	2	2
G protein-coupled receptor kinase 6	0	0	2	2
Tyrosine-protein kinase ZAP-70	0	0	2	2
Tyrosine-protein kinase SYK	0	1	2	3
26S proteasome regulatory subunit 6B	0	0	2	2
Mitogen-activated protein kinase 8	0	0	2	2
Mitogen-activated protein kinase 9	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 4	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 3	0	0	2	2
Casein kinase I isoform alpha	0	1	2	3
Casein kinase I isoform delta	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	2	3
MAP kinase-activated protein kinase 2	0	1	2	3
Cyclin-dependent kinase 8	0	0	2	2
Elongation factor Tu, mitochondrial	0	0	2	2
Choline-phosphate cytidylyltransferase A	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	2	2
Casein kinase I isoform epsilon	0	0	2	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	2	2
Dual specificity protein kinase CLK1	0	0	2	2
Dual specificity protein kinase CLK2	0	0	2	2
Dual specificity protein kinase CLK3	0	0	2	2
Glycogen synthase kinase-3 alpha	0	0	2	2
Glycogen synthase kinase-3 beta	0	0	2	2
Cyclin-dependent kinase 7	0	0	2	2
Cyclin-dependent kinase 9	0	0	2	2
Ras-related protein Rab-27A	0	0	2	2
Tyrosine-protein kinase Blk	0	2	2	4
Interleukin-1 receptor-associated kinase 1	0	0	2	2
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Ribosomal protein S6 kinase alpha-3	0	1	2	3
Cytoplasmic tyrosine-protein kinase BMX	0	0	2	2
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	2	2
Serine/threonine-protein kinase Nek2	0	0	2	2
Serine/threonine-protein kinase Nek3	0	0	2	2
Serine/threonine-protein kinase Nek4	0	0	2	2
Tyrosine-protein kinase JAK3	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 6	0	0	2	2
Serine/threonine-protein kinase PLK1	0	0	2	2
Death-associated protein kinase 1	0	0	2	2
LIM domain kinase 1	0	1	2	3
LIM domain kinase 2	0	1	2	3
Mitogen-activated protein kinase 12	0	1	2	3
Mitogen-activated protein kinase 10	0	0	2	2
Tyrosine--tRNA ligase, cytoplasmic	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-1	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	2	2
Ephrin type-B receptor 3	0	0	2	2
Ephrin type-A receptor 5	0	0	2	2
Ephrin type-B receptor 4	0	1	2	3
Ephrin type-B receptor 1	0	0	2	2
Ephrin type-A receptor 4	0	0	2	2
Adenylate kinase 2, mitochondrial	0	0	2	2
Adenosine kinase	0	0	2	2
Hormonally up-regulated neu tumor-associated kinase	0	0	2	2
Serine/threonine-protein kinase SIK1	0	2	2	4
Receptor-interacting serine/threonine-protein kinase 4	0	0	2	2
Ras-related protein Rab-10	0	0	2	2
Cell division control protein 2 homolog	0	0	2	2
Actin-related protein 3	0	0	2	2
Actin-related protein 2	0	0	2	2
Calcium-dependent protein kinase 1	0	0	2	2
GTP-binding nuclear protein Ran	0	0	2	2
Tubulin alpha-1A chain	0	0	1	1
Casein kinase II subunit alpha	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	2	2
SRSF protein kinase 2	0	0	2	2
Casein kinase I isoform gamma-2	0	0	2	2
DNA-dependent protein kinase catalytic subunit	0	1	0	1
Mitogen-activated protein kinase kinase kinase 9	0	0	2	2
Serine/threonine-protein kinase PknB	0	0	2	2
Cyclin-dependent kinase 3	0	0	2	2
Cyclin-dependent kinase-like 1	0	0	2	2
Cyclin-dependent kinase 6	0	0	2	2
Cyclin-dependent-like kinase 5	0	0	2	2
Cyclin-dependent kinase 16	0	0	2	2
Cyclin-dependent kinase 17	0	0	2	2
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	2	0	2
ATP-dependent 6-phosphofructokinase, platelet type	0	0	2	2
Protein kinase C epsilon type	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 1	0	1	2	3
Angiopoietin-1 receptor	0	0	2	2
Mitogen-activated protein kinase kinase kinase 10	0	0	2	2
DNA topoisomerase 2-beta	0	0	2	2
Protein kinase C theta type	0	0	2	2
Activin receptor type-1	0	0	2	2
Macrophage-stimulating protein receptor	0	0	2	2
Focal adhesion kinase 1	0	1	2	3
Protein kinase C zeta type	0	1	2	3
Protein kinase C delta type	0	1	2	3
Tyrosine-protein kinase BTK	0	2	2	4
Tyrosine-protein kinase receptor TYRO3	0	0	2	2
Cyclin-dependent kinase 18	0	0	2	2
Activated CDC42 kinase 1	0	1	2	3
Epithelial discoidin domain-containing receptor 1	0	5	2	7
Tyrosine-protein kinase ITK/TSK	0	1	2	3
Myotonin-protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase 12	0	0	2	2
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	2	2
Serine/threonine-protein kinase PAK 1	0	0	2	2
Dual specificity mitogen-activated protein kinase kinase 5	0	0	2	2
Mitogen-activated protein kinase 7	0	0	2	2
Serine/threonine-protein kinase PAK 2	0	0	2	2
Serine/threonine-protein kinase 3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 1	0	0	2	2
cGMP-dependent protein kinase 2	0	0	2	2
Integrin-linked protein kinase	0	0	2	2
Rho-associated protein kinase 1	0	0	2	2
Non-receptor tyrosine-protein kinase TNK1	0	0	2	2
Serine/threonine-protein kinase PRP4 homolog	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	2	2
Voltage-dependent L-type calcium channel subunit alpha-1S	0	2	0	2
Activin receptor type-2B	0	0	2	2
Bone morphogenetic protein receptor type-2	0	0	2	2
Protein-tyrosine kinase 6	0	1	2	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
cGMP-dependent protein kinase 1	0	0	2	2
Cyclin-dependent kinase 13	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1	0	0	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	2	2
Protein-tyrosine kinase 2-beta	0	0	2	2
Sodium channel protein type 5 subunit alpha	0	2	0	2
Maternal embryonic leucine zipper kinase	0	0	2	2
Structural maintenance of chromosomes protein 1A	0	0	2	2
Chromodomain-helicase-DNA-binding protein 4	0	0	2	2
Peroxisomal acyl-coenzyme A oxidase 1	0	0	1	1
Serine/threonine-protein kinase D1	0	0	2	2
Serine/threonine-protein kinase 38	0	0	2	2
Receptor tyrosine-protein kinase erbB-4	0	0	2	2
Ribosomal protein S6 kinase alpha-2	0	0	2	2
Ephrin type-A receptor 7	0	0	2	2
Delta(24)-sterol reductase	0	0	2	2
Ribosomal protein S6 kinase alpha-1	0	1	2	3
Dual specificity testis-specific protein kinase 1	0	0	2	2
Myosin light chain kinase, smooth muscle	0	0	2	2
Mitogen-activated protein kinase 11	0	1	2	3
Serine/threonine-protein kinase STK11	0	0	2	2
Rhodopsin kinase GRK1	0	0	2	2
NT-3 growth factor receptor	0	0	2	2
Serine/threonine-protein kinase N1	0	0	2	2
Serine/threonine-protein kinase N2	0	0	2	2
Mitogen-activated protein kinase 14	0	1	4	5
Calcium/calmodulin-dependent protein kinase type IV	0	0	2	2
Mitogen-activated protein kinase kinase kinase 11	0	0	2	2
BDNF/NT-3 growth factors receptor	0	0	2	2
Mitogen-activated protein kinase 6	0	0	2	2
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	2	2
Discoidin domain-containing receptor 2	0	4	2	6
AP2-associated protein kinase 1	0	0	2	2
Myosin light chain kinase 3	0	0	2	2
Uncharacterized aarF domain-containing protein kinase 5	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	2	2
Mitogen-activated protein kinase kinase kinase 19	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	2	2
Serine/threonine-protein kinase TNNI3K	0	0	2	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase MRCK alpha	0	0	2	2
Serine/threonine-protein kinase MRCK gamma	0	0	2	2
Acyl-CoA dehydrogenase family member 10	0	0	2	2
Serine/threonine-protein kinase Nek5	0	0	2	2
Serine/threonine-protein kinase N3	0	0	2	2
Breakpoint cluster region protein	0	1	0	1
Serine/threonine-protein kinase ULK3	0	0	2	2
Dual serine/threonine and tyrosine protein kinase	0	0	2	2
Mitogen-activated protein kinase kinase kinase 15	0	0	2	2
Uncharacterized protein FLJ45252	0	0	2	2
Acyl-CoA dehydrogenase family member 11	0	0	2	2
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	2	2
Serine/threonine-protein kinase MARK2	0	0	2	2
Serine/threonine-protein kinase TAO1	0	0	2	2
STE20-related kinase adapter protein alpha	0	0	2	2
Myosin-14	0	0	2	2
AarF domain-containing protein kinase 1	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	2	2
Serine/threonine-protein kinase 32C	0	0	2	2
Serine/threonine-protein kinase pim-3	0	0	2	2
ATP-dependent RNA helicase DDX42	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	2	2
Myosin light chain kinase family member 4	0	0	2	2
Homeodomain-interacting protein kinase 1	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1D	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	2	2
Cyclin-dependent kinase-like 3	0	0	2	2
MAP kinase-activated protein kinase 5	0	0	2	2
Serine/threonine-protein kinase BRSK2	0	0	2	2
Serine/threonine-protein kinase NIM1	0	0	2	2
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	2	2
Misshapen-like kinase 1	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	2	2
Casein kinase I isoform alpha-like	0	0	2	2
Homeodomain-interacting protein kinase 4	0	0	2	2
Myosin-IIIa	0	0	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	2	2
Serine/threonine-protein kinase Nek11	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	2	2
Mitogen-activated protein kinase 15	0	0	2	2
Serine/threonine-protein kinase Nek9	0	0	2	2
Serine/threonine-protein kinase BRSK1	0	0	2	2
Serine/threonine-protein kinase 35	0	0	2	2
Serine/threonine-protein kinase Nek7	0	0	2	2
Rhodopsin kinase GRK7	0	0	2	2
Serine/threonine-protein kinase 32A	0	0	2	2
Myosin-IIIb	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	2	2
Cyclin-dependent kinase-like 2	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	2	2
Serine/threonine-protein kinase Sgk3	0	0	2	2
Atypical kinase COQ8B, mitochondrial	0	0	2	2
Aurora kinase B	0	1	2	3
MAP/microtubule affinity-regulating kinase 4	0	0	2	2
Calcium/calmodulin-dependent protein kinase type 1G	0	0	2	2
Serine/threonine-protein kinase Nek1	0	0	2	2
Cyclin-dependent kinase 15	0	0	2	2
ATPase family AAA domain-containing protein 5	5	0	0	5
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	2	2
EKC/KEOPS complex subunit TP53RK	0	0	2	2
Dual specificity testis-specific protein kinase 2	0	0	2	2
SRSF protein kinase 1	0	0	2	2
Protein cereblon	0	2	2	6
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	2	2	4
Mitogen-activated protein kinase kinase kinase 5	0	0	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	2	2
Mitogen-activated protein kinase kinase kinase 3	0	0	2	2
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO1	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase RIO2	0	0	2	2
Cyclin-dependent kinase 19	0	0	2	2
Transient receptor potential cation channel subfamily M member 6	0	0	2	2
Testis-specific serine/threonine-protein kinase 1	0	0	2	2
Angiotensin-converting enzyme 2	0	0	1	1
Serine/threonine-protein kinase 33	0	0	2	2
Nucleolar GTP-binding protein 1	0	0	2	2
Serine/threonine-protein kinase D2	0	0	2	2
Serine/threonine-protein kinase DCLK3	0	0	2	2
NUAK family SNF1-like kinase 2	0	0	2	2
RNA cytidine acetyltransferase	0	0	2	2
Serine/threonine-protein kinase SIK2	0	1	2	3
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	2	2
STE20-like serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase TAO3	0	0	2	2
Homeodomain-interacting protein kinase 2	0	0	2	2
Tyrosine-protein kinase Srms	0	0	2	2
Homeodomain-interacting protein kinase 3	0	0	2	2
Serine/threonine-protein kinase PLK3	0	0	2	2
dCTP pyrophosphatase 1	0	0	2	2
Dual specificity protein kinase CLK4	0	0	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	2	2
Serine/threonine-protein kinase Nek6	0	0	2	2
Casein kinase I isoform gamma-1	0	0	2	2
Serine/threonine-protein kinase PAK 6	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	2	2
Serine/threonine-protein kinase LATS2	0	0	2	2
Serine/threonine-protein kinase 36	0	0	2	2
Phenylalanine--tRNA ligase beta subunit	0	0	2	2
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
BMP-2-inducible protein kinase	0	0	2	2
Obg-like ATPase 1	0	0	2	2
Midasin	0	0	2	2
Interleukin-1 receptor-associated kinase 4	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	2	2
Mitogen-activated protein kinase kinase kinase 20	0	0	2	2
Cyclin-dependent kinase 12	0	0	2	2
Serine/threonine-protein kinase PLK2	0	0	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	2	2
Serine/threonine-protein kinase MARK1	0	0	2	2
Serine/threonine-protein kinase pim-2	0	0	2	2
Serine/threonine-protein kinase PAK 5	0	0	2	2
Serine/threonine-protein kinase 26	0	0	2	2
eIF-2-alpha kinase GCN2	0	0	2	2
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	2	2
Serine/threonine-protein kinase NLK	0	0	2	2
Phosphatidylinositol 4-kinase beta	0	0	2	2
Serine/threonine-protein kinase 17A	0	0	2	2
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	2	2
Ephrin type-A receptor 6	0	0	2	2
5'-AMP-activated protein kinase subunit gamma-2	0	0	2	2
Serine/threonine-protein kinase TBK1	0	0	2	2
Septin-9	0	0	2	2
Death-associated protein kinase 2	0	0	2	2
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
Ribosomal protein S6 kinase alpha-6	0	0	2	2
TRAF2 and NCK-interacting protein kinase	0	0	2	2
Serine/threonine-protein kinase tousled-like 1	0	0	2	2
Serine/threonine-protein kinase TAO2	0	0	2	2
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
ALK tyrosine kinase receptor	0	0	2	2
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	3	0	3
SRSF protein kinase 3	0	0	2	2
Serine/threonine-protein kinase ICK	0	0	2	2
Cyclin-dependent kinase 11A	0	0	2	2
Aurora kinase C	0	0	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	2	2
RAC-gamma serine/threonine-protein kinase	0	1	2	3
Serine/threonine-protein kinase 38-like	0	0	2	2
Microtubule-associated serine/threonine-protein kinase 1	0	0	2	2
Serine/threonine-protein kinase SIK3	0	1	2	3
Mitogen-activated protein kinase kinase kinase 2	0	0	2	2
Thyroid hormone receptor-associated protein 3	0	0	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	2	2
Receptor-interacting serine/threonine-protein kinase 3	0	0	2	2
Serine/threonine-protein kinase MRCK beta	0	0	2	2
Interleukin-1 receptor-associated kinase 3	0	0	2	2
Serine/threonine-protein kinase 24	0	0	2	2
NF-kappa-B essential modulator	0	1	0	1
Casein kinase I isoform gamma-3	0	0	2	2
Mitogen-activated protein kinase kinase kinase 4	0	0	2	2
pregnane X receptor	1	0	0	1
hypoxia-inducible factor 1 alpha subunit	3	0	0	3
G	5	0	0	5
IDH1	3	0	0	3
activating transcription factor 6	2	0	0	2
lysosomal alpha-glucosidase preproprotein	3	0	0	3
heat shock protein beta-1	3	0	0	3
urokinase-type plasminogen activator precursor	1	0	0	1
plasminogen precursor	1	0	0	1
urokinase plasminogen activator surface receptor precursor	1	0	0	1
Vpr	1	0	0	1
Solute carrier family 22 member 2	0	1	0	1
Cytochrome P450 2B1	0	1	0	1
HLA class I histocompatibility antigen, B alpha chain	5	0	0	5
Estrogen receptor	0	4	1	5
Glucocorticoid receptor	0	8	0	8
Sex hormone-binding globulin	0	0	2	2
Glycine receptor subunit alpha-1	0	8	0	8
Cytochrome P450 3A4	0	2	0	3
Neuronal acetylcholine receptor subunit alpha-4	2	0	0	2
Adenosine receptor A3	0	2	0	2
Neuronal acetylcholine receptor subunit beta-2	2	0	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Androgen receptor	0	8	0	8
Alpha-1B adrenergic receptor	0	2	0	2
Glycine receptor subunit beta	0	8	0	8
UDP-glucuronosyltransferase 1A1	0	1	0	2
Glycine receptor subunit alpha-2	0	8	0	8
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Glycine receptor subunit alpha-3	0	8	0	8
Adenosine receptor A2a	0	2	0	2
Mu-type opioid receptor	0	2	0	2
Kappa-type opioid receptor	0	2	0	2
Alpha-1A adrenergic receptor	0	2	0	2
Sulfotransferase 1A1	0	2	1	4
Aldehyde oxidase	0	1	0	1
TAR DNA-binding protein 43	1	0	0	1
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Inositol hexakisphosphate kinase 1	5	0	0	5
Estrogen receptor beta	0	1	1	2
Multidrug and toxin extrusion protein 1	0	1	0	1
cytochrome P450 2C9, partial	5	0	0	5
ATP-dependent phosphofructokinase	3	0	0	3
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	4	0	0	4
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	2	0	0	2
Chain A, Dihydrofolate reductase	0	0	1	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	3	0	0	3
acid sphingomyelinase	1	0	0	1
glp-1 receptor, partial	2	0	0	2
glucocerebrosidase	1	0	0	1
alpha-galactosidase	2	0	0	2
nuclear factor erythroid 2-related factor 2 isoform 2	2	0	0	2
DNA polymerase beta	1	0	0	1
Thymidylate synthase	0	2	0	2
Thymidylate synthase	0	1	0	1
Dihydrofolate reductase	0	0	1	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Alpha-synuclein	2	0	0	2
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Solute carrier organic anion transporter family member 1A3	0	1	0	1
Folylpolyglutamate synthase, mitochondrial	0	0	0	1
Multidrug resistance associated protein	0	0	0	1
thioredoxin reductase	2	0	0	2
SMAD family member 2	4	0	0	4
SMAD family member 3	4	0	0	4
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	2	0	0	2
DNA polymerase iota isoform a (long)	2	0	0	2
DNA repair protein RAD52 homolog isoform a	0	0	0	1
Cytochrome P450 2C8	0	0	0	1
Cytochrome P450 3A5	0	0	0	1
Chain A, Beta-lactamase	2	0	0	2
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	2	0	0	2
Parkin	1	0	0	1
bromodomain adjacent to zinc finger domain 2B	2	0	0	2
NPC intracellular cholesterol transporter 1 precursor	1	0	0	1
peripheral myelin protein 22 isoform 1	1	0	0	1
cytochrome P450 2C9 precursor	1	0	0	1
atrial natriuretic peptide receptor 1 precursor	1	0	0	1
phosphoethanolamine/phosphocholine phosphatase isoform 1	0	1	0	1
ras-related protein Rab-9A	1	0	0	1
serine/threonine-protein kinase PLK1	1	0	0	1
M-phase phosphoprotein 8	1	0	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
ATP-dependent translocase ABCB1	0	1	0	1
Microtubule-associated protein tau	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	1	0	1	2
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Cytochrome P450 2J2	0	2	0	2
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
nonstructural protein 1	1	0	0	1
muscleblind-like protein 1 isoform 1	1	0	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	3
Hormone-sensitive lipase	0	1	0	1
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Caspase-1	0	1	0	1
Adenosine receptor A2a	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Aldo-keto reductase family 1 member C3	0	1	0	1
Caspase-3	0	1	0	1
Caspase-4	0	1	0	1
Caspase-5	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Caspase-9	0	1	0	1
Prostaglandin G/H synthase 2	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Solute carrier family 22 member 6	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	2
Estrogen receptor	0	0	1	1
Progesterone receptor	0	2	2	4
Estrogen receptor beta	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Carbonic anhydrase 12	0	1	0	1
Solute carrier family 22 member 3	0	1	0	1
Carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Low-density lipoprotein receptor	0	1	0	1
Fibronectin	0	1	0	1
Carbonic anhydrase 3	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
DNA topoisomerase 2-alpha	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Carbonic anhydrase 4	0	1	0	1
Carbonic anhydrase 6	0	1	0	1
Carbonic anhydrase 5A, mitochondrial	0	1	0	1
Myosin-10	0	0	1	1
Carbonic anhydrase 7	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Carbonic anhydrase 9	0	1	0	1
Rab-like protein 3	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Multidrug resistance-associated protein 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 9	0	1	0	1
Carbonic anhydrase 15	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
Carbonic anhydrase 14	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	1	0	1
Cereblon isoform 4	0	2	0	2
arylsulfatase A	1	0	0	1
Bloom syndrome protein isoform 1	1	0	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Chain A, PLASMINOGEN	0	0	1	1
Chain A, PLASMINOGEN	0	0	1	1
Plasminogen	0	2	1	3
Urokinase-type plasminogen activator	0	1	0	1
Albumin	0	0	1	1
Albumin	0	0	1	1
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Protease	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (74)

Protein Targets (944)

Antral Vascular Ectasia

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (74)

Drugs Studied (37)

Protein Targets (944)