Page last updated: 2024-08-05 15:47:28
MTP inhibitor
An inhibitor that interferes with the action of MTP.
ChEBI ID: 72298
Members (1)
Member | Definition | Class |
bms201038 | A member of the class of benzamides obtained by formal condensation of the carboxy group of 4'-(trifluoromethyl)biphenyl-2-carboxylic acid with the primary amino group of 9-[4-(4-aminopiperidin-1-yl)butyl]-N-(2,2,2-trifluoroethyl)-9H-fluorene-9-carboxamide. Used (as its mesylate salt) as a complement to a low-fat diet and other lipid-lowering treatments in patients with homozygous familial hypercholesterolemia. | lomitapide |
Research
Studies (114)
Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 7 (6.14) | 29.6817 |
2010's | 83 (72.81) | 24.3611 |
2020's | 24 (21.05) | 2.80 |
Study Types
Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
Trials | 13 (10.16%) | 5.53% |
Reviews | 52 (40.63%) | 6.00% |
Case Studies | 15 (11.72%) | 4.05% |
Observational | 3 (2.34%) | 0.25% |
Other | 45 (35.16%) | 84.16% |
Protein Targets (10)
Potency Measurements
Inhibition Measurements