Page last updated: 2024-08-05 15:33:27
reaction intermediate
Any chemical substance produced during the conversion of a reactant to a product.
ChEBI ID: 64297
Members (1)
| Member | Definition | Class |
|---|---|---|
| 4-methylimidazole | Imidazole substituted at position 4 by a methyl group. | 4-methylimidazole |
Research
Studies (120)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|---|---|
| pre-1990 | 9 (7.50) | 18.7374 |
| 1990's | 11 (9.17) | 18.2507 |
| 2000's | 23 (19.17) | 29.6817 |
| 2010's | 64 (53.33) | 24.3611 |
| 2020's | 13 (10.83) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|---|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 2 (1.63%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 121 (98.37%) | 84.16% |
Protein Targets (6)
Potency Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| aldehyde dehydrogenase 1 family, member A1 | Homo sapiens (human) | Potency | 0.2818 | 1 | 1 |
| AR protein | Homo sapiens (human) | Potency | 18.6690 | 2 | 2 |
| geminin | Homo sapiens (human) | Potency | 0.0366 | 1 | 1 |
| RAR-related orphan receptor gamma | Mus musculus (house mouse) | Potency | 12.4501 | 2 | 2 |
Inhibition Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Glutaminyl-peptide cyclotransferase | Homo sapiens (human) | IC50 | 110.0000 | 1 | 1 |
Activation Measurements
| Protein | Taxonomy | Measurement | Average (mM) | Bioassay(s) | Drugs |
|---|---|---|---|---|---|
| Peptidyl-prolyl cis-trans isomerase FKBP5 | Homo sapiens (human) | Kd | 2,900.0000 | 1 | 1 |