Any member of the class of indoles carrying at least one hydroxy group.
| Member | Definition | Role |
|---|
| 2-(8-methoxy-4-methyl-1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)-N-(3-propan-2-yloxypropyl)acetamide | | 2-(8-methoxy-4-methyl-1-oxo-[1,2,4]triazino[4,5-a]indol-2-yl)-N-(3-propan-2-yloxypropyl)acetamide |
| 2-hydroxy-3-(5-((morpholin-4-yl)methyl)pyridin-2-yl)-1h-indole-5-carbonitrile | A member of the class of hydroxyindoles that is 1H-indole substituted by hydroxy, 5-(morpholin-4-ylmethyl)pyridin-2-yl, and cyano groups at positions 2, 3 and 5, respectively. It is a potent, brain permeable inhibitor of human GSK3alpha and GSK3beta with Ki of 6.9 nM and 31 nM, respectively. The drug was being developed by AstraZeneca for the treatment of Alzheimer's disease (clinical trial now discontinued). | AZD1080 |
| 3-(1-methyl-4-piperidinyl)-1H-indol-5-ol | | 3-(1-methyl-4-piperidinyl)-1H-indol-5-ol |
| 3-hydroxy-2-oxoindole | An oxindole that is 1,3-dihydro-2H-indol-2-one substituted by a hydroxy group at position 3. | 3-hydroxyindolin-2-one |
| 3-hydroxy-3-methyloxindole | A methylindole that is 1,3-dihydro-2H-indol-2-one substituted by methyl and a hydroxy group at position 3. | 3-hydroxy-3-methyloxindole |
| 4-hydroxyindole | A member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 4. | 4-hydroxyindole |
| 5-hydroxyindole | A member of the class of hydroxyindoles that is 1H-indole in which the hydrogen at position 5 has been replaced by a hydroxy group. | 5-hydroxyindole |
| hydroxyindoleacetaldehyde | An aldehyde that is acetaldehyde substituted by a 5-hydroxyindol-3-yl group. | (5-hydroxyindol-3-yl)acetaldehyde |
| indigo | | Indigo dye |
| indoxyl | A member of the class of hydroxyindoles that is 1H-indole substituted by a hydroxy group at position 3. | indoxyl |
| N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide | | N-(1,3-benzodioxol-5-yl)-2-[(8-methoxy-5H-[1,2,4]triazino[5,6-b]indol-3-yl)thio]acetamide |
| n-(2-(5-methoxy-2-oxo-2,3-dihydro-1h-indol-3-yl)ethyl)acetamide | A member of the class of hydroxyindoles that is melatonin in which the hydrogen at position 2 of the indole ring has been replaced by a hydroxy group. A predominant hydroxylated melatonin metabolite in plants. | 2-hydroxymelatonin |
| N-(2-hydroxy-5-methoxy-1H-indol-3-yl)acetamide | | N-(2-hydroxy-5-methoxy-1H-indol-3-yl)acetamide |
| n-(p-coumaroyl)serotonin | | N6-cis-p-Coumaroylserotonin |
| n-feruloylserotonin | A member of the class of hydroxyindoles that is the N-feruloyl derivative of serotonin. | N-feruloylserotonin |
| pp242 | A member of the class of pyrazolopyrimidines that is 1H-pyrazolo[3,4-d]pyrimidine substituted by isopropyl, 5-hydroxyindol-2-yl and amino groups at positions 1, 3 and 4 respectively. It is a potent inhibitor of mTOR and exhibits anti-cancer properties. | torkinib |
| psilocin | A tryptamine alkaloid that is N,N-dimethyltryptamine carrying an additional hydroxy substituent at position 4. A hallucinogenic alkaloid isolated in trace amounts from Psilocybe mushrooms (also known as Teonanacatl or "magic mushrooms"). | psilocin |