Ph 1 Chromosome

An aberrant form of human CHROMOSOME 22 characterized by translocation of the distal end of chromosome 9 from 9q34, to the long arm of chromosome 22 at 22q11. It is present in the bone marrow cells of 80 to 90 per cent of patients with chronic myelocytic leukemia (LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE).

Synonym
Ph1 Chromosome
Ph 1 Chromosome
Philadelphia Chromosome

Excerpt	Reference
"The Philadelphia chromosome is formed from a translocation of genetic material involving human chromosomes 9 and 22."	( Steinberg, M, 2007)
"The presence of the Philadelphia chromosome is a poor prognosis factor in acute lymphoblastic leukemia (ALL), in both children and adults."	( Enrico, A; Milone, JH, 2009)
"The Philadelphia chromosome is present in approximately 20% to 30% of adults with acute lymphoblastic leukemia (ALL)."	( Fielding, AK, 2010)
"The Philadelphia chromosome is the most common cytogenetic abnormality found in adult patients diagnosed with acute lymphoblastic leukemia."	( Cortes, J; Kantarjian, H; Mathisen, MS; O'Brien, S; Ravandi, F; Thomas, D, 2011)
"The Philadelphia chromosome is found in 30% of acute lymphoblastic leukemia (ALL) patients, a distinct ALL subgroup where the BCR-ABL fusion gene is associated with poor prognosis."	( Leotta, S; Manzella, L; Massimino, M; Milone, G; Pennisi, MS; Puma, A; Romano, C; Sapienza, G; Scalise, L; Stagno, F; Stella, S; Tirrò, E; Vitale, SR, 2019)
"The Philadelphia chromosome is associated with a poor prognosis in acute lymphoblastic leukemia (ALL)."	( Akhtari, M; Aldoss, I; Chang, J; Douer, D; Ghaznavi, Z; Jeong, AR; Lee, KJ; Vahdani, G; Weissman, A; Yaghmour, G; Zhang, S, 2019)

Excerpt	Reference
"Fifteen patients with Philadelphia chromosome (Ph)-positive chronic myelogenous leukemia (CML) who were ineligible for allogeneic bone marrow transplantation (BMT) or alpha-interferon therapy were included in this study."	( Deisseroth, AB; Dicke, K; Jagannath, S; Kantarjian, HM; LeMaistre, CF; Spinolo, J; Spitzer, G; Talpaz, M; Yau, J, 1991)
"Nine previously untreated patients with Philadelphia chromosome-positive chronic myelocytic leukemia (CML) were treated with recombinant interferon alpha 2a (rIFN-alpha 2a) and hydroxyurea."	( Anger, B; Bartram, C; Heimpel, H; Heinze, B; Leichtle, R; Porzsolt, F, 1989)
"Eleven patients with Philadelphia chromosome (Ph1)-positive chronic myelogenous leukemia (CML) in blast crisis (ten patients) or accelerated disease (one patient) were treated with piperazinedione (PIP) and fractionated total body irradiation (TBI) followed by autologous bone marrow transplantation (ABMT)."	( Dicke, KA; Hester, JP; Jagannath, S; Kantarjian, HM; McCredie, KB; Spitzer, G; Trujillo, J; Vellekoop, L; Zagars, G; Zander, AR, 1986)
"Using Philadelphia chromosome-positive (Ph+) chronic myelogenous leukemia (CML) as a model, our aim has been to develop a molecular cytogenetic method of high resolution analysis for monitoring the frequency of cells with nonrandom chromosome rearrangements in the bone marrow of patients receiving treatment for hematologic malignancies."	( Champlin, RE; Deisseroth, AB; Kantarjian, HM; Ro, JY; Robinson, JR; Seong, DC; Siciliano, MJ; Talpaz, M; Xu, J, 1995)
"We measured the percentage of Philadelphia chromosome (Ph)-negative cells in the autologous cells collected after conventional-dose chemotherapy-induced myelosuppression before autologous transplant and in the marrow of these same CML patients after autologous transplantation of these cells into recipients treated with the cyclophosphamide, VP-16, and TBI."	( Calvert, L; Claxton, D; Durett, A; Giralt, S; Hamer, J; Kantarjian, H; Khouri, I; Liang, J; Talpaz, M; Tibbits, P, 1995)
"Mobilization of Philadelphia chromosome (Ph) negative peripheral blood stem cells has been reported subsequent to intensive chemotherapy."	( Aulitzky, WE; Busemann, C; Huber, C; Huhn, D; Kolbe, K; Neubauer, A; Peschel, C; Schleiermacher, E; Schneller, F; Siegert, W, 1996)
"A 3-year-old girl with Philadelphia chromosome positive acute lymphoblastic leukemia developed pulmonary aspergillosis during severe neutropenia by re-induction therapy."	( Chiba, S; Hatakeyama, N; Hori, T; Imamura, M; Kudoh, T; Mizue, N; Oda, T; Suzuki, N; Watanabe, J, 2001)
"We report a patient with Philadelphia chromosome positive (Ph +ve) chronic myelogenous leukemia (CML), treated with hydroxyurea alone, who upon disease progression developed an additional Ph - ve clone containing chromosomal abnormalities typical of myelodysplastic syndrome (MDS)."	( Flamm, MJ; Murty, VV; Nichols, GL; Rao, PH, 2002)
"We report a 44-yr-old female with Philadelphia chromosome positive chronic myeloid leukemia who was initially treated with busulfan, and clinical remission has been achieved."	( Colovic, M; Krtolica, K; Radojkovic, M; Ristic, S; Todoric, B, 2001)
"The mandate for routine Philadelphia chromosome testing is magnified by the availability of targeted therapy and its greater efficacy in early stage disease."	( Popat, U; Rice, L, 2005)
"A particular VPA/ATRA responsiveness of Philadelphia chromosome-positive (Ph+) acute lymphatic leukemia (ALL) was confirmed in a therapy-refractory patient in vivo."	( Barth, PJ; Burchert, A; Cai, D; Neubauer, A; Ottmann, OG; Wang, Y, 2006)
"Five Philadelphia chromosome positive (Ph+) chronic myeloid leukemia (CML) patients with additional chromosome abnormalities at diagnosis have been followed during Imatinib therapy."	( Donti, E; Gozzetti, A; Ronconi, S; Spedicato, F; Valenti, AM; Zaccaria, A, 2007)
"Treating Philadelphia chromosome-positive (Ph+) ALL patients with conventional chemotherapy has not substantially improved their long-term outcomes."	( Martinelli, G; Paolini, S; Piccaluga, PP, 2007)
"To investigate the change of Philadelphia chromosome-positive clone with secondary chromosomal aberrations after imatinib mesylate (IM) treatment in patients with chronic myeloid leukemia (CML) and its relation with prognosis."	( Chen, SS; Huang, XJ; Jiang, B; Jiang, Q; Qiu, JY; Zhang, Y, 2007)
"The percentage of Philadelphia chromosome-positive clone with secondary chromosomal aberrations showed the following 4 types of change; amplification, no change, decrease and complete remission after treatment with IM."	( Chen, SS; Huang, XJ; Jiang, B; Jiang, Q; Qiu, JY; Zhang, Y, 2007)
"The percentage of Philadelphia chromosome-positive clone with secondary chromosomal aberrations may drop in some CML patients after IM treatment and the patients may gain CCyR with accompanied prolonged survival."	( Chen, SS; Huang, XJ; Jiang, B; Jiang, Q; Qiu, JY; Zhang, Y, 2007)
"Additional chromosomal aberrations in Philadelphia chromosome-positive chronic myeloid leukemia are non-random and strongly associated with disease progression, but their prognostic impact and effect on treatment response is not clear."	( Bommer, C; Daniel, P; Dörken, B; Kim, TD; Koca, G; le Coutre, P; Nogai, H; Schwarz, M; Türkmen, S, 2010)
"Between 2000 and 2007, 53 patients with Philadelphia chromosome-negative ALL (40 with B-ALL and 13, T-ALL) received treatment."	( Intermesoli, T; Jenner, M; Krishnan, S; Lister, A; MacDougall, F; Rohatiner, A, 2011)
"Intensified treatment of Philadelphia chromosome negative acute lymphoblastic leukemia (Ph(-)ALL) in adolescents by pediatric teams, with fve years disease free survival (DFS) rate of 65%, encouraged the use of intensified protocols in patients between 15 and 30 years, improving the DFS from 45% to 60-80%."	( Aspillaga, A; Cabrera, ME; Calderón, S; Guerra, C; Lois, V; Molina, J; Muñoz, L; Pilleux, L; Pizarro, A; Puga, B; Rojas, C; Rojas, H; Vergara, CG, 2014)
"We treated 90 relapsed/refractory Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph(-)-ALL) patients with CAG regimen [cytarabine (10mg/m(2)/12h, days 1-14), aclarubicin (5-7 mg/m(2)/day, days 1-8), granulocyte colony-stimulating factor (200 μg/m(2)/day, days 1-14)], 82 relapsed/refractory Ph(-)-ALL patients were treated with increasing aclarubicin dose CAG (5-7 mg/m(2)/day, days 1-14, HD-CAG)."	( Jiao, W; Li, X; Liu, L; Qu, Q; Wu, D; Zhang, Y, 2015)
"Treatment of Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph(+)ALL) remains a challenge."	( Chang, BH; Druker, BJ; Eide, CA; Hayes-Lattin, B; Leonard, JT; Loriaux, M; Rowley, JS; Spurgeon, SE; Traer, E; Tyner, JW, 2016)
"The outcome of adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia (Ph- ALL) relapsing after pediatric-inspired front-line therapy is ill known."	( Asnafi, V; Bastié, JN; Bay, JO; Beldjord, K; Béné, MC; Bernard, M; Charbonnier, A; Chevallier, P; Desjonquères, A; Dombret, H; Himberlin, C; Huguet, F; Hunault, M; Ifrah, N; Isnard, F; Lafage-Pochitaloff, M; Leguay, T; Lepretre, S; Lhéritier, V; Lioure, B; Renaud, M; Tavernier, E; Thomas, X; Turlure, P, 2016)
"In patients with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) treated with chemotherapy plus a tyrosine kinase inhibitor (TKI), the prognostic impact of additional chromosomal abnormalities (ACAs) is not well-established."	( Benton, CB; Cameron Yin, C; Cortes, JE; Daver, NG; Garcia-Manero, G; Garris, R; Issa, GC; Jabbour, E; Jain, N; Kadia, TM; Kantarjian, HM; Khouri, M; Ko, H; Konopleva, M; O'Brien, SM; Patel, K; Ravandi, F; Sasaki, K; Short, NJ; Thomas, D, 2017)
"Herein, we describe a patient with Philadelphia chromosome-positive B-ALL who relapsed after CD19-directed CAR-T therapy, but subsequently responded to the combination of blinatumomab and the tyrosine kinase inhibitor ponatinib, with the achievement of a complete remission lasting 12 months."	( Baer, MR; Duong, VH; El Chaer, F; Emadi, A; Hardy, NM; Holtzman, NG; Koka, R; Law, JY; Lee, ST; Sausville, EA; Singh, ZN, 2019)
"Patients with Philadelphia chromosome (Ph)-positive or Ph-like ALL with ABL-class fusion should be treated with dasatinib."	( Pui, CH, 2020)
"The outcomes of Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) can improve with allogeneic hematopoietic stem cell transplantation (HSCT) during the first complete remission after treatment with a tyrosine kinase inhibitor (TKI) combined with chemotherapy."	( Guo, YM; Kuzume, A; Minami, Y; Sato, N; Yamauchi, N; Yuda, J, 2021)
"The standard treatment for adults with Philadelphia chromosome-positive (Ph+) acute lymphoblastic leukemia (ALL) in Japan is imatinib-based chemotherapy followed by allogeneic hematopoietic stem cell transplantation (HSCT)."	( Atsuta, Y; Cho, R; Dobashi, N; Doki, N; Fujisawa, S; Fujita, H; Hagihara, M; Hata, T; Hatta, Y; Hayakawa, F; Hiramoto, N; Hirano, D; Ishikawa, Y; Ito, T; Kako, S; Kamae, T; Kobayashi, Y; Matsuda, M; Miyazaki, Y; Naoe, T; Nishiwaki, S; Ohtake, S; Onoda, M; Ozawa, Y; Sakura, T; Suehiro, Y; Sugiura, I; Tanaka, M; Taniguchi, Y; Tsuji, M; Ueda, Y; Yokoyama, H, 2022)
"The clinical outcome of Philadelphia chromosome-negative B cell acute lymphoblastic leukemia (Ph-neg B-ALL) varies considerably from one person to another after clinical treatment due to lack of targeted therapies and leukemia's heterogeneity."	( Cao, Y; Chen, S; Hong, Y; Sun, A; Tian, X; Xiang, X; Yu, Y; Zeng, Z; Zhang, L, 2021)
"The outcome of children with Philadelphia chromosome-positive (Ph-positive) acute lymphoblastic leukaemia significantly improved with the combination of imatinib and intensive chemotherapy."	( Biondi, A; Borowitz, MJ; Cario, G; Carroll, AJ; Cazzaniga, G; Devidas, M; Gastier-Foster, JM; Heerema, NA; Hunger, SP; Loh, ML; Martin-Regueira, P; Moorman, AV; Raetz, EA; Reshmi, SC; Saha, V; Schrappe, M; Schultz, KR; Silverman, LB; Slayton, WB; Tran, TH; Valsecchi, MG, 2023)
"A 72-year-old man with Philadelphia chromosome-positive acute lymphoblastic leukemia (Ph+ALL) was treated with dasatinib (week1: 50 mg/day, week2: 70 mg/day, week3-: 100 mg/day) and prednisolone from June 2017."	( Fujiwara, R; Hanamoto, H; Hashimoto, H; Katoh, Y; Shimada, T; Tamura, Y; Yamada, K, 2023)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	53 (6.32)	23.3326
1990's	106 (12.63)	12.5806
2000's	256 (30.51)	18.1394
2010's	297 (35.40)	28.8240
2020's	127 (15.14)	9.53

Drug	Relationship Strength	Studies	Trials
salicylic acid	low	1	0
dimethyl sulfoxide	low	1	0
histamine	low	1	0
hydrogen	medium	2	1
niacinamide	medium	2	1
aspirin	low	1	0
azathioprine	low	2	0
busulfan	medium	36	5
caffeine	low	1	0
verapamil	medium	1	1
carmustine	low	1	0
chlorambucil	low	1	0
valproic acid	low	2	0
erythrosine	low	1	0
fluorouracil	low	2	0
foscarnet	low	1	0
hydroxyurea	medium	62	9
ifosfamide	medium	4	3
2-propanol	low	1	0
2-(4-morpholinyl)-8-phenyl-4h-1-benzopyran-4-one	low	1	0
mechlorethamine	low	1	0
metformin	low	1	0
mitoxantrone	medium	4	1
entinostat	medium	1	1
pd 98059	low	1	0
4-phenylbutyric acid	low	1	0
phenylbutazone	low	1	0
pipobroman	low	1	0
procarbazine	low	1	0
vorinostat	low	1	0
thalidomide	low	2	0
thiotepa	low	2	0
n,n,n',n'-tetrakis(2-pyridylmethyl)ethylenediamine	low	1	0
prednisolone	medium	16	4
thymidine	low	1	0
prednisone	medium	23	4
lysine	low	1	0
edetic acid	low	1	0
p-dimethylaminoazobenzene	low	1	0
tyrosine	low	7	0
leucine	low	1	0
phenylalanine	low	2	0
colchicine	low	1	0
cytarabine	medium	55	13
asparagine	medium	1	1
valine	low	2	0
threonine	low	1	0
methylprednisolone	low	1	0
1,3-butadiene	low	1	0
pyrroles	low	1	0
thiophenes	low	1	0
quinazolines	low	7	0
benzoxazoles	low	1	0
thiazoles	medium	60	3
pyrazines	medium	5	1
azacitidine	medium	9	1
fusarium	low	1	0
indirubin	low	1	0
reticulin	medium	1	1
alpha-aminopyridine	low	1	0
deoxycytidine	low	2	0
arsenic trioxide	low	2	0
digoxigenin	low	1	0
mannose	low	1	0
vidarabine	low	6	0
4-(4-dimethylaminophenylazo)benzoic acid	low	1	0
silver	low	3	0
terbium	low	1	0
europium	low	1	0
gold	medium	1	1
camptothecin	low	1	0
trolamine salicylate	low	2	0
tetradecanoylphorbol acetate	low	3	0
daunorubicin	medium	19	7
phosphotyrosine	low	3	0
etoposide	medium	14	6
ribavirin	low	1	0
nimustine	low	1	0
vindesine	medium	3	1
idarubicin	medium	17	5
gemcitabine	low	1	0
irinotecan	low	1	0
capecitabine	low	1	0
tocophersolan	low	1	0
voriconazole	low	1	0
ranimustine	low	1	0
ubenimex	low	1	0
bendamustine hydrochloride	low	1	0
fibrinogen	low	3	0
mafosfamide	low	3	0
fingolimod hydrochloride	low	1	0
3,6-bis(5-chloro-2-piperidyl)-2,5-piperazinedione	low	1	0
annamycin	low	1	0
clofarabine	medium	4	1
imatinib mesylate	medium	391	41
n-methylisoindigotin	low	1	0
methotrexate	medium	26	7
birb 796	low	1	0
sorafenib	low	1	0
lenalidomide	low	2	0
demecolcine	medium	1	1
homoharringtonine	low	2	0
bortezomib	low	4	0
carboplatin	medium	1	1
leptomycin b	low	1	0
mevalonic acid	low	1	0
tretinoin	low	6	0
tacrolimus	low	1	0
thapsigargin	low	1	0
bms 214662	low	1	0
aclarubicin	low	1	0
decitabine	low	5	0
aphidicolin	low	2	0
melphalan	medium	2	1
isomethyleugenol	low	8	0
s 1033	medium	45	8
isopropyl thiogalactoside	medium	1	1
fludarabine	low	4	0
mercaptopurine	medium	9	2
capsaicin	medium	1	1
thioguanine anhydrous	low	3	0
nelarabine	low	3	0
e 7010	low	1	0
dasatinib	medium	133	13
sphingosine	low	1	0
dinoprostone	low	1	0
thromboxane a2	low	1	0
amphotericin b	low	2	0
sirolimus	low	1	0
herbimycin	low	2	0
casein kinase ii	low	1	0
ag-490	low	1	0
ag 127	low	1	0
bosutinib	medium	12	6
arsenic	low	4	0
vx680	medium	3	2
panobinostat	low	1	0
mocetinostat	low	6	0
on012380	low	1	0
abt-737	low	1	0
inno-406	low	1	0
danusertib	medium	1	1
trametinib	low	1	0
losartan potassium	low	2	0
acid phosphatase	low	1	0
oligonucleotides	low	5	0
idarubicinol	medium	1	1
bucladesine	low	1	0
sgi 1776	low	1	0
ponatinib	medium	53	8
incb-018424	low	22	0
5-(4-amino-1-propan-2-yl-3-pyrazolo[3,4-d]pyrimidinyl)-1,3-benzoxazol-2-amine	low	1	0
abt-199	low	6	0
cudc-907	low	1	0
salicylates	low	1	0
cyclin d1	low	1	0
nitrophenols	low	1	0
enasidenib	low	1	0
vitamin b 12	low	1	0
cyclosporine	low	5	0
muramidase	low	1	0
exudates	low	1	0
acyclovir	low	1	0
levoleucovorin	low	1	0
guanine	low	1	0
folic acid	low	1	0
dacarbazine	medium	2	2
raltitrexed	low	1	0
allopurinol	low	1	0
bl 4162a	low	5	0
pemetrexed	low	1	0
cytidylyl-3'-5'-guanosine	low	1	0
metallothionein	low	1	0
pyrimidinones	low	1	0

Protein Targets (1,742)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, Proto-oncogene serine/threonine-protein kinase Pim-1	0	1	0	1
Chain A, HADH2 protein	14	0	0	14
Chain B, HADH2 protein	14	0	0	14
Chain A, 2-oxoglutarate Oxygenase	14	0	0	14
Chain A, Cruzipain	7	0	0	7
Chain A, Methyltransferase Wbdd	0	1	0	1
thioredoxin reductase	26	0	0	26
15-lipoxygenase, partial	10	0	0	10
ATAD5 protein, partial	20	0	0	20
NFKB1 protein, partial	9	0	0	9
TDP1 protein	56	0	0	56
Thrombopoietin	11	0	0	11
aldehyde dehydrogenase 1 family, member A1	29	0	0	29
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	11	0	0	11
thyroid stimulating hormone receptor	18	0	0	18
regulator of G-protein signaling 4	15	0	0	15
EWS/FLI fusion protein	57	0	0	57
67.9K protein	21	0	0	21
Parkin	9	0	0	9
euchromatic histone-lysine N-methyltransferase 2	39	0	0	39
cytochrome P450 2D6 isoform 1	4	0	0	4
cellular tumor antigen p53 isoform a	12	0	0	12
cytochrome P450 2C19 precursor	6	0	0	6
cytochrome P450 2C9 precursor	5	0	0	5
chromobox protein homolog 1	26	0	0	26
flap endonuclease 1	9	0	0	9
serine/threonine-protein kinase mTOR isoform 1	12	0	0	12
survival motor neuron protein isoform d	25	0	0	25
cytochrome P450 3A4 isoform 1	18	0	0	18
M-phase phosphoprotein 8	9	0	0	9
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	6	8	15
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	3	0	3
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit alpha	0	1	0	1
Serine/threonine-protein kinase PLK4	0	3	13	16
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	1	7	8
Gamma-aminobutyric acid receptor subunit pi	18	0	0	18
Polyunsaturated fatty acid lipoxygenase ALOX15B	5	0	0	5
Bromodomain-containing protein 4	0	5	0	5
5-hydroxytryptamine receptor 4	0	6	0	6
cGMP-specific 3',5'-cyclic phosphodiesterase	0	1	0	1
Integrin beta-3	9	1	0	10
Cytochrome P450 1A2	0	5	1	6
Integrin alpha-IIb	9	1	0	10
Neuronal acetylcholine receptor subunit alpha-4	0	1	0	1
Serine/threonine-protein kinase pim-1	0	5	14	19
Neuronal acetylcholine receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	18	0	0	18
Gamma-aminobutyric acid receptor subunit delta	18	0	0	18
Gamma-aminobutyric acid receptor subunit gamma-2	18	0	0	18
Casein kinase II subunit alpha'	0	5	13	18
Gamma-aminobutyric acid receptor subunit alpha-5	18	0	0	18
Gamma-aminobutyric acid receptor subunit alpha-3	18	0	0	18
Gamma-aminobutyric acid receptor subunit gamma-1	18	0	0	18
Gamma-aminobutyric acid receptor subunit alpha-2	18	0	0	18
Proteinase-activated receptor 1	0	0	0	1
Bromodomain-containing protein 2	0	1	0	1
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	4	0	5
5-hydroxytryptamine receptor 2A	0	5	0	5
5-hydroxytryptamine receptor 2C	0	7	0	7
Gamma-aminobutyric acid receptor subunit alpha-4	18	0	0	18
Gamma-aminobutyric acid receptor subunit gamma-3	18	0	0	18
Gamma-aminobutyric acid receptor subunit alpha-6	18	0	0	18
Sodium-dependent serotonin transporter	0	3	0	3
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
5-hydroxytryptamine receptor 2B	0	11	0	11
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	8	8	17
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	6	8	16
Serine/threonine-protein kinase mTOR	0	9	9	18
Serine/threonine-protein kinase mTOR	0	1	0	1
Histamine H2 receptor	8	1	1	10
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	7	8	16
Glycogen synthase kinase-3 beta	0	6	13	19
D(1A) dopamine receptor	7	0	0	7
Serine/threonine-protein kinase PLK1	0	7	13	20
Gamma-aminobutyric acid receptor subunit alpha-1	18	1	0	19
Gamma-aminobutyric acid receptor subunit beta-3	18	0	0	18
Gamma-aminobutyric acid receptor subunit beta-2	18	0	0	18
Casein kinase II subunit beta	0	5	0	5
Casein kinase II subunit alpha	0	6	7	13
DNA-dependent protein kinase catalytic subunit	0	6	0	6
Mu-type opioid receptor	0	1	1	2
Serine-protein kinase ATM	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	3	0	3
Serine/threonine-protein kinase ATR	0	2	3	5
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	3	0	3
Bromodomain-containing protein 3	0	1	0	1
Serine/threonine-protein kinase pim-3	0	3	7	10
Phosphoinositide 3-kinase regulatory subunit 5	0	1	0	1
GABA theta subunit	18	0	0	18
Gamma-aminobutyric acid receptor subunit epsilon	18	0	0	18
Serine/threonine-protein kinase PLK3	0	5	7	12
Serine/threonine-protein kinase PLK2	0	4	7	11
ATP-dependent phosphofructokinase	27	0	0	27
hypoxia-inducible factor 1 alpha subunit	12	0	0	12
RAR-related orphan receptor gamma	34	0	0	34
GLI family zinc finger 3	34	0	0	34
AR protein	49	0	0	49
retinoic acid nuclear receptor alpha variant 1	39	0	0	39
retinoid X nuclear receptor alpha	33	0	0	33
estrogen nuclear receptor alpha	55	0	0	55
peroxisome proliferator-activated receptor delta	18	0	0	18
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	30	0	0	30
activating transcription factor 6	20	0	0	20
v-jun sarcoma virus 17 oncogene homolog (avian)	14	0	0	14
Histone H2A.x	24	0	0	24
thyroid hormone receptor beta isoform a	13	0	0	13
heat shock protein beta-1	7	0	0	7
nuclear factor erythroid 2-related factor 2 isoform 1	36	0	0	36
lamin isoform A-delta10	33	0	0	33
Voltage-dependent calcium channel gamma-2 subunit	28	0	0	28
Glutamate receptor 2	29	0	0	29
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	27	0	0	27
Chain A, Putative fructose-1,6-bisphosphate aldolase	7	0	0	7
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
Luciferase	19	0	0	19
glp-1 receptor, partial	12	0	0	12
WRN	3	0	0	3
phosphopantetheinyl transferase	18	0	0	18
Hsf1 protein	0	0	1	1
thioredoxin glutathione reductase	8	0	0	8
bromodomain adjacent to zinc finger domain 2B	8	0	0	8
NPC intracellular cholesterol transporter 1 precursor	7	0	0	7
vitamin D3 receptor isoform VDRA	18	0	0	18
nuclear factor erythroid 2-related factor 2 isoform 2	20	0	0	20
importin subunit beta-1 isoform 1	6	0	0	6
DNA polymerase beta	6	0	0	6
ras-related protein Rab-9A	13	0	0	13
serine/threonine-protein kinase PLK1	2	0	0	2
snurportin-1	6	0	0	6
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	6	0	0	6
DNA polymerase eta isoform 1	6	0	0	6
DNA polymerase iota isoform a (long)	19	0	0	19
nuclear receptor ROR-gamma isoform 1	17	0	0	17
DNA polymerase kappa isoform 1	15	0	0	15
muscleblind-like protein 1 isoform 1	12	0	0	12
Rap guanine nucleotide exchange factor 3	3	0	0	3
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain A, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
Chain B, AROMATIC AMINO ACID AMINOTRANSFERASE	0	0	1	1
mitogen-activated protein kinase 1	14	0	0	14
Histone deacetylase 3	0	16	4	23
Histone deacetylase 4	0	12	2	17
Histone deacetylase 1	0	17	6	26
Histone deacetylase 7	0	12	3	18
Histone deacetylase 2	0	16	6	25
Polyamine deacetylase HDAC10	0	10	2	15
Histone deacetylase 11	0	11	2	16
Histone deacetylase 8	0	15	3	21
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	4	0	4
Histone deacetylase 6	0	15	5	23
Histone deacetylase 9	0	11	2	16
Histone deacetylase 5	0	13	2	18
Fumarate hydratase	30	0	0	30
PPM1D protein	29	0	0	29
G	20	0	0	20
polyprotein	30	0	0	30
Interferon beta	44	0	0	44
HLA class I histocompatibility antigen, B alpha chain	20	0	0	20
Rapamycin-insensitive companion of mTOR	0	1	0	1
Regulatory-associated protein of mTOR	0	2	0	2
Phosphatidylinositol 3-kinase catalytic subunit type 3	0	1	1	2
Inositol hexakisphosphate kinase 1	20	0	0	20
Target of rapamycin complex 2 subunit MAPKAP1	0	1	0	1
Target of rapamycin complex subunit LST8	0	2	0	2
cytochrome P450 2C9, partial	20	0	0	20
Apoptosis regulator Bcl-2	0	5	4	9
Spike glycoprotein	23	0	4	27
Bcl-2-like protein 1	0	5	2	7
Induced myeloid leukemia cell differentiation protein Mcl-1	0	4	0	4
Aspartyl/asparaginyl beta-hydroxylase	0	2	0	2
Bcl-2-related protein A1	0	2	1	3
Bcl-2-like protein 2	0	3	0	3
Bcl2-associated agonist of cell death	0	2	0	2
Chain A, Apoptosis regulator Bcl-X	0	1	0	1
Bcl-2-like protein 11	0	1	0	1
Beta-casein	0	1	0	1
Alpha-1B adrenergic receptor	0	6	0	6
Alpha-2B adrenergic receptor	0	1	0	1
Alpha-2C adrenergic receptor	0	1	0	1
Alpha-2A adrenergic receptor	0	1	0	1
Adenosine receptor A2a	0	4	0	9
BH3-interacting domain death agonist	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1 homolog	0	0	1	1
Apoptosis regulator BAX	0	1	1	2
Bcl-2 homologous antagonist/killer	0	2	1	3
Bcl-2-binding component 3, isoforms 1/2	0	1	0	1
Bcl-2-like protein 10	0	1	0	1
72 kDa type IV collagenase	0	3	0	3
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Ferritin light chain	15	0	0	15
Thymidine kinase	0	2	0	3
GLS protein	19	0	0	19
Smad3	14	0	0	14
arylsulfatase A	15	0	0	15
Bloom syndrome protein isoform 1	22	0	0	22
hemoglobin subunit beta	8	0	0	8
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	6	0	0	6
Solute carrier family 22 member 1	0	5	0	8
ATP-binding cassette sub-family C member 3	0	36	0	36
Multidrug resistance-associated protein 4	0	36	0	39
Solute carrier family 22 member 6	0	2	0	3
Bile salt export pump	0	7	0	7
Bile salt export pump	0	46	0	46
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	3	0	7
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	10	1	11
Cytochrome P450 2J2	0	3	0	3
Disintegrin and metalloproteinase domain-containing protein 17	3	0	0	3
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	1	0	4
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	2	0	5
Canalicular multispecific organic anion transporter 1	0	37	0	38
Thymidine kinase	0	2	0	3
Epidermal growth factor receptor	0	15	13	28
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	20	0	0	20
endonuclease IV	8	0	0	8
chaperonin-containing TCP-1 beta subunit homolog	3	0	0	3
USP1 protein, partial	19	0	0	19
Microtubule-associated protein tau	16	0	0	16
apical membrane antigen 1, AMA1	7	0	0	7
nonstructural protein 1	7	0	0	7
NPYLR7B	0	0	2	2
glucocerebrosidase	10	0	0	10
IDH1	16	0	0	16
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	7	0	0	7
peripheral myelin protein 22 isoform 1	13	0	0	13
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	13	0	0	13
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	4	0	0	4
potassium voltage-gated channel subfamily H member 2 isoform d	11	0	0	11
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
GTP-binding nuclear protein Ran isoform 1	2	0	0	2
urokinase-type plasminogen activator precursor	15	0	0	15
plasminogen precursor	15	0	0	15
urokinase plasminogen activator surface receptor precursor	15	0	0	15
geminin	47	0	0	47
muscarinic acetylcholine receptor M1	12	0	0	12
lethal factor (plasmid)	11	0	0	11
pyruvate kinase PKM isoform b	3	0	0	3
Tyrosine-protein kinase JAK2	0	6	12	18
Receptor tyrosine-protein kinase erbB-2	0	6	7	13
Ornithine decarboxylase	3	0	0	4
Tyrosine-protein kinase JAK1	0	4	14	18
Glutamate receptor ionotropic, NMDA 1	0	1	0	5
Tyrosine-protein kinase JAK3	0	4	7	11
Glutamate receptor ionotropic, NMDA 2A	0	1	0	5
Glutamate receptor ionotropic, NMDA 2B	0	2	0	6
Glutamate receptor ionotropic, NMDA 2C	0	1	0	5
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
large T antigen	0	2	0	2
interleukin 8	10	0	0	10
estrogen receptor 2 (ER beta)	19	0	0	19
progesterone receptor	23	0	0	23
glucocorticoid receptor [Homo sapiens]	38	0	0	38
estrogen-related nuclear receptor alpha	49	0	0	49
transcriptional regulator ERG isoform 3	5	0	0	5
thyroid hormone receptor beta isoform 2	38	0	0	38
Polyphenol oxidase 2	0	2	0	4
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	4
Cellular tumor antigen p53	39	0	0	39
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	4	2	7
Xanthine dehydrogenase/oxidase	0	3	0	3
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
TAR DNA-binding protein 43	4	1	0	5
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	2	0	2
thyroid stimulating hormone receptor	18	0	0	18
Heat shock protein HSP 90-alpha	0	1	1	2
Botulinum neurotoxin type A	0	1	0	1
Neutrophil cytosol factor 1	0	1	0	1
Nitric oxide synthase, endothelial	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, brain	0	1	0	1
Nitric oxide synthase, inducible	0	1	0	1
Kappa-type opioid receptor	0	2	1	3
Phosphatidylinositol 4-kinase alpha	0	1	0	1
Tyrosine-protein kinase	0	0	1	1
Phosphatidylinositol 4-kinase type 2-beta	0	1	0	1
Phosphatidylinositol 4-kinase type 2-alpha	0	1	0	1
Phosphatidylinositol 4-kinase beta	0	1	7	8
farnesoid X nuclear receptor	28	0	0	28
vitamin D (1,25- dihydroxyvitamin D3) receptor	20	0	0	20
tumor necrosis factor	1	0	0	1
peripheral myelin protein 22	23	0	0	23
Cytochrome P450 3A4	0	15	2	19
Cytochrome P450 2D6	0	6	1	7
Cytochrome P450 2C19	0	7	1	8
Nuclear receptor ROR-gamma	12	1	1	14
Potassium voltage-gated channel subfamily H member 2	0	13	0	13
Aurora kinase B	0	6	13	19
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	11	1	15
huntingtin isoform 2	11	0	0	11
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase beta	0	1	0	1
DNA polymerase beta	0	1	0	1
DNA polymerase catalytic subunit	0	2	0	2
DNA polymerase catalytic subunit	0	2	0	2
DNA polymerase alpha catalytic subunit	0	2	1	3
DNA polymerase delta catalytic subunit	0	2	0	2
DNA polymerase catalytic subunit	0	1	0	1
DNA polymerase subunit gamma-1	0	1	0	1
DNA polymerase lambda	0	1	0	1
peroxisome proliferator activated receptor gamma	25	0	0	25
nuclear receptor subfamily 1, group I, member 2	8	0	0	8
Carbonic anhydrase 1	0	9	0	14
Carbonic anhydrase 2	0	11	1	18
Neutral amino acid transporter A	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Carbonic anhydrase-like protein, putative	0	0	0	4
Amino acid transporter	0	1	0	1
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	2	2
ras protein, partial	0	0	2	2
hypothetical protein, conserved	4	0	0	4
cytochrome P450 family 3 subfamily A polypeptide 4	31	0	0	31
cytochrome P450 2D6	19	0	0	19
Rac1 protein	0	0	2	2
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	2	2
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Fatty acid-binding protein, liver	0	2	0	2
Myeloperoxidase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	1	0	1
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	7	0	7
Adenosine receptor A1	0	3	0	7
Substance-P receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	6	7	13
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	2	2
Prostaglandin G/H synthase 2	0	2	0	2
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	3	0	3
Solute carrier family 22 member 20	0	4	0	4
Solute carrier family 22 member 6	0	4	0	4
Sigma non-opioid intracellular receptor 1	0	0	2	2
Sigma non-opioid intracellular receptor 1	0	0	2	2
Chain A, Beta-lactamase	9	0	0	9
pregnane X receptor	8	0	0	8
nuclear receptor subfamily 1, group I, member 3	32	0	0	32
pregnane X nuclear receptor	33	0	0	33
aryl hydrocarbon receptor	18	0	0	18
histone acetyltransferase KAT2A isoform 1	14	0	0	14
Adenosine receptor A3	0	7	0	7
DNA (cytosine-5)-methyltransferase 1	0	3	0	3
Adenosine receptor A1	0	3	1	6
Multidrug and toxin extrusion protein 1	0	4	0	4
Histone-lysine N-methyltransferase EHMT2	0	3	0	3
ATPase family AAA domain-containing protein 5	24	0	0	24
Ataxin-2	31	0	0	31
acetylcholinesterase	14	0	0	14
SMAD family member 2	7	0	0	7
SMAD family member 3	7	0	0	7
P53	1	0	0	1
Protein-arginine deiminase type-4	0	2	0	2
Chain A, p38 MAP kinase	0	0	1	1
Chain A, p38 MAP kinase	0	0	1	1
Leukotriene C4 synthase	0	0	7	7
GALC protein	6	0	0	6
tyrosine-protein kinase Yes	12	0	0	12
Serine/threonine-protein kinase Sgk1	0	2	0	2
Bone morphogenetic protein receptor type-1B	0	0	13	13
Serine/threonine-protein kinase 25	0	0	7	7
Citron Rho-interacting kinase	0	0	13	13
Serine/threonine-protein kinase RIO3	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 7	0	0	7	7
Serine/threonine-protein kinase Chk1	0	2	14	16
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	3	7	11
Peripheral plasma membrane protein CASK	0	0	7	7
Aurora kinase A	0	7	13	20
Cyclin-G-associated kinase	0	1	13	14
Serine/threonine-protein kinase DCLK1	0	0	7	7
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	1	7	8
Muscle, skeletal receptor tyrosine-protein kinase	0	0	7	7
Ephrin type-B receptor 6	0	0	13	13
Mitogen-activated protein kinase 13	0	2	8	10
3-phosphoinositide-dependent protein kinase 1	0	1	7	8
Mitogen-activated protein kinase kinase kinase 13	0	0	7	7
Death-associated protein kinase 3	0	1	7	8
Mitogen-activated protein kinase kinase kinase 7	0	1	7	8
Receptor-interacting serine/threonine-protein kinase 2	0	5	13	18
NUAK family SNF1-like kinase 1	0	1	7	8
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	7	7
Cyclin-T1	0	1	0	1
Rho-associated protein kinase 2	0	1	13	14
Serine/threonine-protein kinase ULK1	0	0	13	13
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	13	13
Ribosomal protein S6 kinase alpha-5	0	1	13	14
Ribosomal protein S6 kinase alpha-4	0	1	13	14
Serine/threonine-protein kinase 16	0	0	13	13
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	7	7
Serine/threonine-protein kinase PAK 3	0	1	7	8
Cyclin-dependent kinase-like 5	0	0	11	11
Serine/threonine-protein kinase 17B	0	1	7	8
Serine/threonine-protein kinase 10	0	2	13	15
Serine/threonine-protein kinase D3	0	0	14	14
Cyclin-dependent kinase 14	0	1	7	8
Mitogen-activated protein kinase kinase kinase 6	0	0	12	12
Serine/threonine-protein kinase OSR1	0	0	7	7
Mitogen-activated protein kinase kinase kinase kinase 4	0	1	13	14
Serine/threonine-protein kinase LATS1	0	0	13	13
Serine/threonine-protein kinase PAK 4	0	2	13	15
Serine/threonine-protein kinase Chk2	0	1	7	8
Tyrosine-protein kinase ABL1	0	18	17	37
Tyrosine-protein kinase ABL1	0	4	0	4
Tumor necrosis factor	0	0	1	1
RAF proto-oncogene serine/threonine-protein kinase	0	6	7	13
High affinity nerve growth factor receptor	0	4	12	16
Heat shock protein beta-1	0	1	0	1
Protein kinase C gamma type	0	2	1	3
Protein kinase C beta type	0	3	13	16
Insulin receptor	0	5	13	18
Tyrosine-protein kinase Lck	0	11	13	25
Tyrosine-protein kinase Fyn	0	6	13	19
Cyclin-dependent kinase 1	0	3	12	15
Tyrosine-protein kinase Fes/Fps	0	2	13	15
Macrophage colony-stimulating factor 1 receptor	0	6	7	13
Tyrosine-protein kinase Yes	0	5	13	18
Tyrosine-protein kinase Lyn	0	7	13	20
Proto-oncogene tyrosine-protein kinase receptor Ret	0	6	13	19
Insulin-like growth factor 1 receptor	0	5	13	18
ATP-dependent translocase ABCB1	0	8	3	21
Hepatocyte growth factor receptor	0	4	13	17
Tyrosine-protein kinase HCK	0	7	13	20
Proto-oncogene tyrosine-protein kinase ROS	0	2	7	9
Platelet-derived growth factor receptor beta	0	6	13	19
Tyrosine-protein kinase Fgr	0	2	10	12
Wee1-like protein kinase 2	0	0	7	7
Uncharacterized serine/threonine-protein kinase SBK3	0	0	7	7
Mast/stem cell growth factor receptor Kit	0	9	9	18
Fibroblast growth factor receptor 1	0	5	13	19
Myosin light chain kinase, smooth muscle	0	0	4	4
Cyclin-dependent kinase 4	0	3	13	16
Proto-oncogene tyrosine-protein kinase Src	0	11	13	25
Insulin receptor-related protein	0	1	7	8
G2/mitotic-specific cyclin-B1	0	3	0	3
Serine/threonine-protein kinase B-raf	0	4	14	18
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	1	13	14
Platelet-derived growth factor receptor alpha	0	7	8	15
Tyrosine-protein kinase Fer	0	2	13	15
Protein kinase C alpha type	0	4	13	17
cAMP-dependent protein kinase catalytic subunit alpha	0	2	13	15
Vascular endothelial growth factor receptor 1	0	3	7	10
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	7	7
Cyclin-A2	0	3	0	3
Serine/threonine-protein kinase MAK	0	0	7	7
Cyclin-dependent kinase 11B	0	1	7	8
Ephrin type-A receptor 1	0	2	12	14
Fibroblast growth factor receptor 2	0	2	7	9
Receptor tyrosine-protein kinase erbB-3	0	0	7	7
Fibroblast growth factor receptor 4	0	2	7	9
Fibroblast growth factor receptor 3	0	2	7	9
cAMP-dependent protein kinase catalytic subunit gamma	0	1	10	11
cAMP-dependent protein kinase catalytic subunit beta	0	1	13	14
Ribosomal protein S6 kinase beta-1	0	1	13	14
Protein kinase C eta type	0	1	8	9
G1/S-specific cyclin-E1	0	2	0	2
Cyclin-dependent kinase 2	0	7	14	21
Activin receptor type-2A	0	0	7	7
Mitogen-activated protein kinase 3	0	3	13	17
MAP/microtubule affinity-regulating kinase 3	0	0	13	13
Mitogen-activated protein kinase 1	0	5	13	18
Ephrin type-A receptor 2	0	5	13	18
Ephrin type-A receptor 3	0	1	7	8
Ephrin type-A receptor 8	0	1	7	8
Ephrin type-B receptor 2	0	3	13	16
Leukocyte tyrosine kinase receptor	0	1	7	8
Non-receptor tyrosine-protein kinase TYK2	0	3	14	17
Wee1-like protein kinase	0	0	13	13
Tyrosine-protein kinase receptor UFO	0	2	7	9
Mitogen-activated protein kinase 4	0	0	7	7
RAC-alpha serine/threonine-protein kinase	0	3	13	16
RAC-beta serine/threonine-protein kinase	0	2	13	15
G protein-coupled receptor kinase 4	0	0	7	7
Dual specificity protein kinase TTK	0	0	13	13
G protein-coupled receptor kinase 5	0	1	0	1
Tyrosine-protein kinase receptor Tie-1	0	1	7	8
Vascular endothelial growth factor receptor 3	0	3	7	10
Vascular endothelial growth factor receptor 2	0	8	8	18
Dual specificity mitogen-activated protein kinase kinase 2	0	2	13	15
Receptor-type tyrosine-protein kinase FLT3	0	12	13	25
Bone morphogenetic protein receptor type-1A	0	0	13	13
Activin receptor type-1B	0	1	13	14
TGF-beta receptor type-1	0	0	13	13
Serine/threonine-protein kinase receptor R3	0	0	11	11
TGF-beta receptor type-2	0	0	13	13
Tyrosine-protein kinase CSK	0	4	13	17
Protein kinase C iota type	0	0	14	14
Megakaryocyte-associated tyrosine-protein kinase	0	0	7	7
Tyrosine-protein kinase Tec	0	2	13	15
Tyrosine-protein kinase TXK	0	2	7	9
Tyrosine-protein kinase ABL2	0	2	13	15
Tyrosine-protein kinase FRK	0	3	13	16
G protein-coupled receptor kinase 6	0	1	9	10
Tyrosine-protein kinase ZAP-70	0	2	7	9
Tyrosine-protein kinase SYK	0	3	13	16
Mitogen-activated protein kinase 8	0	1	13	14
Mitogen-activated protein kinase 9	0	1	13	14
Dual specificity mitogen-activated protein kinase kinase 4	0	0	10	10
Dual specificity mitogen-activated protein kinase kinase 3	0	0	13	13
Mitogen-activated protein kinase 14	0	0	1	1
Casein kinase I isoform alpha	0	3	13	16
Casein kinase I isoform delta	0	0	13	13
MAP kinase-activated protein kinase 2	0	2	13	15
Cyclin-dependent kinase 8	0	3	7	10
Casein kinase I isoform epsilon	0	0	13	13
Dual specificity protein kinase CLK1	0	0	13	13
Dual specificity protein kinase CLK2	0	0	13	13
Dual specificity protein kinase CLK3	0	0	11	11
Glycogen synthase kinase-3 alpha	0	1	13	14
Cyclin-dependent kinase 7	0	1	13	14
Cyclin-dependent kinase 9	0	2	13	15
Tyrosine-protein kinase Blk	0	3	7	10
Interleukin-1 receptor-associated kinase 1	0	1	13	14
Ribosomal protein S6 kinase alpha-3	0	1	13	14
Cytoplasmic tyrosine-protein kinase BMX	0	2	7	9
cAMP-dependent protein kinase catalytic subunit PRKX	0	1	7	8
Serine/threonine-protein kinase Nek2	0	0	13	13
Serine/threonine-protein kinase Nek3	0	1	13	14
Serine/threonine-protein kinase Nek4	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 6	0	0	13	13
Death-associated protein kinase 1	0	1	7	8
LIM domain kinase 1	0	1	13	14
LIM domain kinase 2	0	1	13	14
Mitogen-activated protein kinase 12	0	2	8	10
Mitogen-activated protein kinase 10	0	1	13	14
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	7	8
Ephrin type-B receptor 3	0	1	13	14
Ephrin type-A receptor 5	0	1	13	14
Ephrin type-B receptor 4	0	4	13	17
Ephrin type-B receptor 1	0	1	7	8
Ephrin type-A receptor 4	0	1	13	14
Hormonally up-regulated neu tumor-associated kinase	0	0	7	7
Serine/threonine-protein kinase SIK1	0	2	7	9
Receptor-interacting serine/threonine-protein kinase 4	0	0	7	7
Cell division control protein 2 homolog	0	0	7	7
Calcium-dependent protein kinase 1	0	0	7	7
Tubulin alpha-1A chain	0	0	4	4
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	7	7
SRSF protein kinase 2	0	0	7	7
Casein kinase I isoform gamma-2	0	0	13	13
Cyclin-A1	0	2	0	2
Mitogen-activated protein kinase kinase kinase 9	0	1	7	8
Serine/threonine-protein kinase PknB	0	0	7	7
Cyclin-dependent kinase 3	0	1	12	13
Cyclin-dependent kinase-like 1	0	0	7	7
Cyclin-dependent-like kinase 5	0	2	13	15
Cyclin-dependent kinase 16	0	1	13	14
Cyclin-dependent kinase 17	0	1	13	14
Protein kinase C epsilon type	0	1	8	9
Dual specificity mitogen-activated protein kinase kinase 1	0	6	13	19
Angiopoietin-1 receptor	0	3	7	10
Mitogen-activated protein kinase kinase kinase 10	0	0	7	7
Protein kinase C theta type	0	1	13	14
Activin receptor type-1	0	0	13	13
Macrophage-stimulating protein receptor	0	1	13	14
Focal adhesion kinase 1	0	3	13	16
Protein kinase C delta type	0	3	14	17
Tyrosine-protein kinase BTK	0	5	13	18
Tyrosine-protein kinase receptor TYRO3	0	0	7	7
Cyclin-dependent kinase 18	0	1	9	10
Activated CDC42 kinase 1	0	2	13	15
Epithelial discoidin domain-containing receptor 1	0	7	13	20
Tyrosine-protein kinase ITK/TSK	0	1	7	8
Myotonin-protein kinase	0	0	7	7
Mitogen-activated protein kinase kinase kinase kinase 2	0	1	13	14
Mitogen-activated protein kinase kinase kinase 12	0	0	7	7
Tyrosine-protein kinase Mer	0	1	10	11
Serine/threonine-protein kinase 4	0	2	13	15
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	13	14
Serine/threonine-protein kinase PAK 1	0	0	7	7
Dual specificity mitogen-activated protein kinase kinase 5	0	0	13	13
Mitogen-activated protein kinase 7	0	0	13	13
Serine/threonine-protein kinase PAK 2	0	1	13	14
Serine/threonine-protein kinase 3	0	1	13	14
Mitogen-activated protein kinase kinase kinase 1	0	0	13	13
cGMP-dependent protein kinase 2	0	0	7	7
Rho-associated protein kinase 1	0	1	13	14
Non-receptor tyrosine-protein kinase TNK1	0	0	13	13
Serine/threonine-protein kinase PRP4 homolog	0	0	7	7
Receptor-interacting serine/threonine-protein kinase 1	0	3	7	10
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	7	8
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	1	13	14
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	1	13	14
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	13	14
Activin receptor type-2B	0	0	13	13
Bone morphogenetic protein receptor type-2	0	0	13	13
Protein-tyrosine kinase 6	0	2	13	15
cGMP-dependent protein kinase 1	0	1	12	13
Cyclin-dependent kinase 13	0	1	13	14
Calcium/calmodulin-dependent protein kinase type 1	0	0	7	7
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	1	13	14
Protein-tyrosine kinase 2-beta	0	2	13	15
Maternal embryonic leucine zipper kinase	0	1	13	14
Cyclin-dependent kinase 5 activator 1	0	2	0	2
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
Serine/threonine-protein kinase D1	0	1	8	9
Serine/threonine-protein kinase 38	0	0	7	7
Receptor tyrosine-protein kinase erbB-4	0	1	7	8
Ribosomal protein S6 kinase alpha-2	0	0	7	7
Ephrin type-A receptor 7	0	1	11	12
Ribosomal protein S6 kinase alpha-1	0	3	13	16
Dual specificity testis-specific protein kinase 1	0	0	13	13
Myosin light chain kinase, smooth muscle	0	0	13	13
TGF-beta-activated kinase 1 and MAP3K7-binding protein 1	0	1	0	1
Mitogen-activated protein kinase 11	0	2	14	16
Serine/threonine-protein kinase STK11	0	0	13	13
Rhodopsin kinase GRK1	0	0	7	7
NT-3 growth factor receptor	0	1	7	8
Serine/threonine-protein kinase N1	0	0	13	13
Serine/threonine-protein kinase N2	0	0	13	13
Mitogen-activated protein kinase 14	0	6	16	22
Calcium/calmodulin-dependent protein kinase type IV	0	0	13	13
Mitogen-activated protein kinase kinase kinase 11	0	0	13	13
BDNF/NT-3 growth factors receptor	0	2	7	9
MAP kinase-activated protein kinase 3	0	1	6	7
Mitogen-activated protein kinase 6	0	0	7	7
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	7	7
Discoidin domain-containing receptor 2	0	7	13	20
AP2-associated protein kinase 1	0	1	13	14
Myosin light chain kinase 3	0	0	12	12
Serine/threonine-protein kinase SBK1	0	0	7	7
Mitogen-activated protein kinase kinase kinase 19	0	0	7	7
Serine/threonine-protein kinase TNNI3K	0	1	7	8
Leucine-rich repeat serine/threonine-protein kinase 2	0	1	7	8
Serine/threonine-protein kinase MRCK alpha	0	0	12	12
Serine/threonine-protein kinase MRCK gamma	0	0	13	13
Serine/threonine-protein kinase Nek5	0	0	7	7
Serine/threonine-protein kinase ULK3	0	0	13	13
Dual serine/threonine and tyrosine protein kinase	0	0	7	7
Mitogen-activated protein kinase kinase kinase 15	0	0	7	7
Serine/threonine-protein kinase MARK2	0	1	13	14
Serine/threonine-protein kinase TAO1	0	0	13	13
Serine/threonine-protein kinase tousled-like 2	0	0	7	7
Serine/threonine-protein kinase 32C	0	0	7	7
Serine/threonine-protein kinase VRK2	0	0	7	7
Myosin light chain kinase family member 4	0	0	7	7
Homeodomain-interacting protein kinase 1	0	2	7	9
Calcium/calmodulin-dependent protein kinase type 1D	0	1	7	8
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	13	13
Cyclin-dependent kinase-like 3	0	0	7	7
MAP kinase-activated protein kinase 5	0	1	13	14
Serine/threonine-protein kinase BRSK2	0	0	7	7
Serine/threonine-protein kinase NIM1	0	1	7	8
Serine/threonine-protein kinase ULK2	0	0	7	7
Misshapen-like kinase 1	0	2	11	13
Serine/threonine-protein kinase DCLK2	0	0	7	7
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	7	7
Casein kinase I isoform alpha-like	0	0	7	7
Homeodomain-interacting protein kinase 4	0	1	7	8
Myosin-IIIa	0	0	7	7
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	7	7
Serine/threonine-protein kinase Nek11	0	0	7	7
Atypical kinase COQ8A, mitochondrial	0	0	13	13
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	13	13
Mitogen-activated protein kinase 15	0	0	13	13
Serine/threonine-protein kinase Nek9	0	0	13	13
Serine/threonine-protein kinase BRSK1	0	1	7	8
Serine/threonine-protein kinase 35	0	0	7	7
Serine/threonine-protein kinase Nek7	0	0	10	10
Rhodopsin kinase GRK7	0	0	7	7
Serine/threonine-protein kinase 32A	0	0	7	7
Myosin-IIIb	0	0	7	7
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	7	7
Cyclin-dependent kinase-like 2	0	0	7	7
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	13	13
Serine/threonine-protein kinase Sgk3	0	0	7	7
Atypical kinase COQ8B, mitochondrial	0	0	7	7
MAP/microtubule affinity-regulating kinase 4	0	0	13	13
Calcium/calmodulin-dependent protein kinase type 1G	0	0	8	8
Testis-specific serine/threonine-protein kinase 2	0	1	0	1
Serine/threonine-protein kinase Nek1	0	0	13	13
Cyclin-dependent kinase 15	0	1	7	8
PAS domain-containing serine/threonine-protein kinase	0	1	11	12
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	13	13
SRSF protein kinase 1	0	0	7	7
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	4	13	17
Mitogen-activated protein kinase kinase kinase 5	0	1	13	14
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	7	7
Mitogen-activated protein kinase kinase kinase 3	0	0	13	13
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	13	13
Serine/threonine-protein kinase RIO1	0	0	7	7
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	7	7
Serine/threonine-protein kinase RIO2	0	0	7	7
Cyclin-dependent kinase 19	0	2	7	9
Transient receptor potential cation channel subfamily M member 6	0	0	7	7
Testis-specific serine/threonine-protein kinase 1	0	0	7	7
Serine/threonine-protein kinase 33	0	1	7	8
Serine/threonine-protein kinase D2	0	1	13	14
Serine/threonine-protein kinase DCLK3	0	0	7	7
NUAK family SNF1-like kinase 2	0	0	12	12
Serine/threonine-protein kinase SIK2	0	1	13	14
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	7	7
STE20-like serine/threonine-protein kinase	0	2	13	15
Serine/threonine-protein kinase TAO3	0	0	13	13
Homeodomain-interacting protein kinase 2	0	1	7	8
Tyrosine-protein kinase Srms	0	0	7	7
Homeodomain-interacting protein kinase 3	0	2	7	9
Dual specificity protein kinase CLK4	0	0	11	11
MAP kinase-interacting serine/threonine-protein kinase 2	0	1	7	8
Serine/threonine-protein kinase Nek6	0	0	7	7
Casein kinase I isoform gamma-1	0	0	13	13
Serine/threonine-protein kinase PAK 6	0	1	10	11
SNF-related serine/threonine-protein kinase	0	0	7	7
Serine/threonine-protein kinase LATS2	0	0	7	7
Serine/threonine-protein kinase 36	0	0	7	7
BMP-2-inducible protein kinase	0	0	13	13
Interleukin-1 receptor-associated kinase 4	0	2	13	15
Serine/threonine-protein kinase 32B	0	0	7	7
Mitogen-activated protein kinase kinase kinase 20	0	1	13	14
Serine/threonine-protein kinase MARK1	0	1	7	8
Serine/threonine-protein kinase pim-2	0	3	11	14
Serine/threonine-protein kinase PAK 5	0	1	7	8
Serine/threonine-protein kinase 26	0	0	13	13
eIF-2-alpha kinase GCN2	0	0	7	7
Serine/threonine-protein kinase NLK	0	1	13	14
Serine/threonine-protein kinase 17A	0	1	7	8
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	7	7
Ephrin type-A receptor 6	0	0	7	7
Serine/threonine-protein kinase TBK1	0	3	13	16
Death-associated protein kinase 2	0	0	7	7
Ribosomal protein S6 kinase alpha-6	0	0	13	13
TRAF2 and NCK-interacting protein kinase	0	1	13	14
Serine/threonine-protein kinase tousled-like 1	0	0	7	7
Serine/threonine-protein kinase TAO2	0	0	13	13
ALK tyrosine kinase receptor	0	2	8	10
SRSF protein kinase 3	0	0	7	7
Serine/threonine-protein kinase ICK	0	0	13	13
Cyclin-dependent kinase 11A	0	0	7	7
Aurora kinase C	0	4	7	11
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	7	7
RAC-gamma serine/threonine-protein kinase	0	2	13	15
Serine/threonine-protein kinase 38-like	0	0	8	8
Microtubule-associated serine/threonine-protein kinase 1	0	0	7	7
Serine/threonine-protein kinase SIK3	0	1	13	14
Mitogen-activated protein kinase kinase kinase 2	0	0	13	13
Serine/threonine-protein kinase WNK2	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	10	10
Mitogen-activated protein kinase kinase kinase kinase 5	0	1	13	14
Serine/threonine-protein kinase MRCK beta	0	1	13	14
Interleukin-1 receptor-associated kinase 3	0	0	13	13
Serine/threonine-protein kinase 24	0	1	11	12
Casein kinase I isoform gamma-3	0	0	13	13
Mitogen-activated protein kinase kinase kinase 4	0	0	13	13
GTPase HRas	0	1	0	2
GTPase KRas	0	1	0	2
Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha	0	1	0	1
Protein farnesyltransferase subunit beta	0	1	0	1
Geranylgeranyl transferase type-1 subunit beta	0	1	0	1
Chain H, Proteasome component PUP1	0	1	0	1
Chain I, Proteasome component PUP3	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Chain K, Proteasome component PRE2	0	1	0	1
Chain L, Proteasome component C5	0	1	0	1
Proteasome subunit beta type-11	0	1	0	1
caspase 7, apoptosis-related cysteine protease	8	0	0	8
caspase-3	8	0	0	8
Caspase-7	6	0	0	6
caspase-3	6	0	0	6
26S proteasome non-ATPase regulatory subunit 11	0	1	0	1
26S proteasome non-ATPase regulatory subunit 12	0	1	0	1
26S proteasome non-ATPase regulatory subunit 14	0	1	0	1
Proteasome subunit alpha type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 3	0	1	0	1
Carbonic anhydrase 12	0	4	0	7
Prothrombin	0	1	0	3
Chymotrypsinogen A	0	1	0	1
Carbonic anhydrase 3	0	3	0	6
Cathepsin B	0	1	0	1
Neutrophil elastase	0	1	0	1
Cathepsin G	0	2	0	2
Lysosomal protective protein	0	1	0	1
Chymotrypsinogen B	0	2	0	2
26S proteasome regulatory subunit 6A	0	1	0	1
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Proteasome subunit beta type-1	0	1	0	2
Carbonic anhydrase 4	0	5	0	8
Carbonic anhydrase 6	0	3	0	6
Chymase	0	1	0	1
Proteasome subunit alpha type-1	0	1	0	1
Proteasome subunit alpha type-2	0	1	0	1
Proteasome subunit alpha type-3	0	1	0	1
Proteasome subunit alpha type-4	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-8	0	1	0	1
Proteasome subunit beta type-9	0	1	0	1
Proteasome subunit alpha type-5	0	1	0	1
Proteasome subunit beta type-4	0	1	0	1
Proteasome subunit beta type-6	0	1	0	1
Proteasome subunit beta type-5	0	3	0	4
Carbonic anhydrase 5A, mitochondrial	0	5	0	8
26S proteasome regulatory subunit 7	0	1	0	1
Lon protease homolog, mitochondrial	0	1	0	1
Proteasome subunit beta type-10	0	1	0	1
Carbonic anhydrase 7	0	4	0	7
26S proteasome regulatory subunit 6B	0	1	12	13
26S proteasome non-ATPase regulatory subunit 8	0	1	0	1
Proteasome subunit beta type-3	0	1	0	1
Proteasome subunit beta type-2	0	1	0	2
26S proteasome non-ATPase regulatory subunit 7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 4	0	1	0	1
26S proteasome complex subunit SEM1	0	1	0	1
Proteasome subunit alpha type-6	0	1	0	1
26S proteasome regulatory subunit 4	0	1	0	1
26S proteasome regulatory subunit 8	0	1	0	1
26S proteasome regulatory subunit 10B	0	1	0	1
Beta-carbonic anhydrase 1	0	1	0	1
Nuclear factor NF-kappa-B p100 subunit	0	1	0	1
Transcription factor p65	0	1	0	1
26S proteasome non-ATPase regulatory subunit 2	0	1	0	1
26S proteasome non-ATPase regulatory subunit 6	0	1	0	1
Proteasomal ubiquitin receptor ADRM1	0	1	0	1
Carbonic anhydrase 9	0	7	0	11
ATP-dependent Clp protease proteolytic subunit	0	1	1	2
Carbonic anhydrase 13	0	1	0	3
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Proteasome subunit alpha-type 8	0	1	0	1
Proteasome subunit beta type-7	0	1	0	1
26S proteasome non-ATPase regulatory subunit 1	0	1	0	1
Carbonic anhydrase 15	0	3	0	6
Carbonic anhydrase 14	0	3	0	6
26S proteasome non-ATPase regulatory subunit 13	0	1	0	1
Carbonic anhydrase 5B, mitochondrial	0	3	0	6
Membrane-associated progesterone receptor component 1	0	0	7	7
Cell division cycle 7-related protein kinase	0	1	9	10
ATP-dependent RNA helicase DDX3X	0	0	12	12
Pyridoxal kinase	0	0	12	12
Peroxisomal acyl-coenzyme A oxidase 3	0	0	12	12
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	12	12
Dynamin-like 120 kDa protein, mitochondrial	0	0	12	12
Eukaryotic translation initiation factor 5B	0	0	8	8
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	12	12
Structural maintenance of chromosomes protein 2	0	0	12	12
ADP/ATP translocase 2	0	0	12	12
Glycogen phosphorylase, liver form	0	0	12	12
Nucleophosmin	0	1	0	1
Signal recognition particle receptor subunit alpha	0	0	10	10
Cytochrome c1, heme protein, mitochondrial	0	0	12	12
Serine/threonine-protein kinase A-Raf	0	1	12	13
Glycogen phosphorylase, brain form	0	0	12	12
Glycogen phosphorylase, muscle form	0	1	0	1
Breakpoint cluster region protein	0	12	15	29
DNA topoisomerase 2-alpha	0	3	10	20
ADP/ATP translocase 3	0	0	12	12
Inosine-5'-monophosphate dehydrogenase 2	0	0	11	11
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	12	12
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	2	13	15
Tyrosine-protein kinase Blk	0	2	0	2
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	12	12
Ras-related protein Rab-6A	0	0	10	10
Platelet-derived growth factor receptor alpha	0	1	0	1
Multifunctional protein ADE2	0	0	12	12
Ferrochelatase, mitochondrial	0	0	12	12
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Beta-adrenergic receptor kinase 1	0	0	12	12
Probable ATP-dependent RNA helicase DDX6	0	0	12	12
Deoxycytidine kinase	0	0	12	15
Phosphatidylethanolamine-binding protein 1	0	0	9	9
Heme oxygenase 2	0	0	12	12
S-adenosylmethionine synthase isoform type-2	0	0	10	10
DnaJ homolog subfamily A member 1	0	0	12	12
DNA replication licensing factor MCM4	0	0	12	12
Myosin-10	0	0	11	11
Glycine--tRNA ligase	0	0	12	12
Exosome RNA helicase MTR4	0	0	12	12
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	10	10
Elongation factor Tu, mitochondrial	0	0	12	12
Choline-phosphate cytidylyltransferase A	0	0	7	7
Cysteine--tRNA ligase, cytoplasmic	0	0	12	12
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	12	12
Ras-related protein Rab-27A	0	0	12	12
Tyrosine--tRNA ligase, cytoplasmic	0	0	12	12
5'-AMP-activated protein kinase subunit gamma-1	0	0	12	13
Adenylate kinase 2, mitochondrial	0	0	12	12
Adenosine kinase	0	0	12	12
Actin-related protein 3	0	0	12	12
Actin-related protein 2	0	0	12	12
GTP-binding nuclear protein Ran	0	0	12	12
Cyclin-dependent kinase 6	0	2	12	14
ATP-dependent 6-phosphofructokinase, platelet type	0	0	11	11
Synaptic vesicular amine transporter	0	1	0	1
DNA topoisomerase 2-beta	0	1	13	22
Platelet-derived growth factor receptor beta	0	1	0	1
Protein kinase C zeta type	0	1	10	11
Integrin-linked protein kinase	0	0	12	12
Structural maintenance of chromosomes protein 1A	0	0	12	12
Chromodomain-helicase-DNA-binding protein 4	0	0	12	12
Peroxisomal acyl-coenzyme A oxidase 1	0	0	11	11
Delta(24)-sterol reductase	0	0	12	12
Uncharacterized aarF domain-containing protein kinase 5	0	0	8	8
Putative heat shock protein HSP 90-beta 2	0	0	12	12
Rab-like protein 3	0	0	7	7
Uncharacterized protein FLJ45252	0	0	12	12
Acyl-CoA dehydrogenase family member 11	0	0	12	12
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	11	11
ATP-dependent RNA helicase DHX30	0	0	6	6
STE20-related kinase adapter protein alpha	0	0	12	12
Myosin-14	0	0	12	12
AarF domain-containing protein kinase 1	0	0	12	12
ATP-dependent RNA helicase DDX42	0	0	7	7
ATP-dependent RNA helicase DDX1	0	0	12	12
EKC/KEOPS complex subunit TP53RK	0	0	12	12
Dual specificity testis-specific protein kinase 2	0	0	10	10
Nucleolar GTP-binding protein 1	0	0	11	11
RNA cytidine acetyltransferase	0	0	12	12
dCTP pyrophosphatase 1	0	0	12	12
Phenylalanine--tRNA ligase beta subunit	0	0	12	12
Isoleucine--tRNA ligase, mitochondrial	0	0	10	10
Obg-like ATPase 1	0	0	11	11
Midasin	0	0	12	12
Cyclin-dependent kinase 12	0	1	12	13
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	11	11
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	11	11
5'-AMP-activated protein kinase subunit gamma-2	0	0	12	13
Septin-9	0	0	12	12
Long-chain-fatty-acid--CoA ligase 5	0	0	7	7
Thyroid hormone receptor-associated protein 3	0	0	12	12
Receptor-interacting serine/threonine-protein kinase 3	0	2	12	14
vasopressin V1b receptor	1	0	0	1
cAMP-dependent protein kinase type I-alpha regulatory subunit	0	0	1	1
cAMP-dependent protein kinase type II-beta regulatory subunit	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta isoform 1	0	0	1	1
relaxin receptor 1 isoform 1	3	0	0	3
relaxin receptor 2 isoform 1	1	0	0	1
neuropeptide S receptor isoform A	3	0	0	3
cAMP-dependent protein kinase catalytic subunit beta isoform 3	0	0	1	1
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	5	0	0	5
Matrix metalloproteinase-9	0	2	0	2
Chain A, Glycogen Phosphorylase	0	1	0	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Chitinase	0	1	0	1
Potassium channel subfamily K member 2	0	0	1	1
Glycogen phosphorylase, muscle form	0	1	0	1
Renin	0	1	0	1
Cholinesterase	0	1	0	1
Glycogen phosphorylase, liver form	0	1	0	1
Glycogen phosphorylase, muscle form	0	1	0	1
Replicase polyprotein 1ab	0	1	4	5
Replicase polyprotein 1ab	0	2	4	6
Amine oxidase [flavin-containing] A	0	3	0	3
Acetylcholinesterase	0	5	0	5
Amine oxidase [flavin-containing] B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	2	0	2
Adenosine receptor A3	0	2	0	2
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	2	0	3
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	2	3
Endochitinase B1	0	1	0	1
Muscarinic acetylcholine receptor	0	0	0	1
Phosphodiesterase	0	1	0	1
Guanine deaminase	0	1	0	2
DNA topoisomerase	0	1	0	1
putative alpha-glucosidase	1	0	0	1
alpha-galactosidase	5	0	0	5
lysosomal alpha-glucosidase preproprotein	3	0	0	3
eukaryotic translation initiation factor 2-alpha kinase 3 isoform 1 precursor	0	0	1	1
Telomerase reverse transcriptase	0	1	0	1
Type-2 restriction enzyme ScaI	0	1	0	1
Deoxyribonuclease-2-alpha	0	1	0	1
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Deoxyribonuclease-1	0	1	0	1
Type-2 restriction enzyme PstI	0	1	0	1
Type-2 restriction enzyme EcoRI	0	1	0	1
DNA ligase	0	1	0	1
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
DNA topoisomerase 1	0	2	1	9
Type-2 restriction enzyme BamHI	0	1	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
Type-2 restriction enzyme HindIII	0	1	0	1
Ribonuclease pancreatic	0	1	0	1
Inositol monophosphatase 1	9	0	0	9
DNA topoisomerase 1	0	1	0	2
DNA topoisomerase 1	0	1	0	1
Integrase	0	3	0	3
DNA topoisomerase type IB small subunit	0	0	1	1
Liver carboxylesterase 1	0	1	0	3
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Transient receptor potential cation channel subfamily V member 1	0	3	1	4
Lysine-specific histone demethylase 1A	0	2	0	2
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	3	0	4
Cannabinoid receptor 1	0	1	0	1
Cannabinoid receptor 2	0	1	0	1
D(2) dopamine receptor	0	1	1	2
Potassium voltage-gated channel subfamily A member 1	0	1	0	1
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	2	1	4
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
Glutathione reductase, mitochondrial	0	3	0	3
Alpha-synuclein	4	1	0	5
Glutathione reductase	0	1	0	1
Chain A, Protein kinase CK2, alpha Subunit	0	1	0	1
Chain A, PROTEIN KINASE CK2, alpha SUBUNIT	0	1	0	1
Chain A, Protein Kinase Ck2, Alpha Subunit	0	1	0	1
dopamine D1 receptor	3	0	0	3
Casein kinase II subunit alpha	0	1	0	1
Casein kinase II subunit beta	0	1	0	1
Casein kinase II subunit alpha 3	0	3	0	3
Single-stranded DNA cytosine deaminase	3	0	0	3
FAD-linked sulfhydryl oxidase ALR	0	0	0	1
Solute carrier organic anion transporter family member 1B3	0	6	0	7
PAX8	0	0	0	5
nuclear receptor subfamily 0 group B member 1	0	3	0	3
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
steroidogenic factor 1	0	3	0	3
caspase-1 isoform alpha precursor	2	0	0	2
Solute carrier family 22 member 3	0	5	0	6
Tubulin alpha-1A chain	0	4	1	5
Tubulin beta chain	0	4	1	5
Plasma kallikrein	0	0	0	4
Tubulin beta-4A chain	0	4	2	7
ATP-dependent translocase ABCB1	0	3	0	3
Tubulin beta chain	0	4	2	7
Tubulin alpha-3C chain	0	4	2	7
ATP-dependent translocase ABCB1	0	3	0	4
Tubulin alpha-1B chain	0	4	2	7
Tubulin alpha-4A chain	0	4	2	7
Tubulin beta-4B chain	0	4	2	7
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	4	2	7
Tubulin beta-2A chain	0	4	2	7
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	4	2	7
Tubulin beta-2B chain	0	5	0	5
Tubulin alpha-3E chain	0	4	2	7
Tubulin alpha-1A chain	0	4	2	7
Similar to alpha-tubulin isoform 1	0	3	0	3
Similar to alpha-tubulin isoform 1	0	3	0	3
CREB-binding protein	1	0	0	1
Tubulin alpha-1C chain	0	4	2	7
Tubulin beta-6 chain	0	4	2	7
Tubulin beta-2B chain	0	4	2	7
Tubulin beta-1 chain	0	4	2	7
Nuclear receptor corepressor 2	0	7	0	7
LMP1 [Human herpesvirus 4]	0	0	0	3
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	4	0	4
transactivating tegument protein VP16 [Human herpesvirus 1]	0	4	0	4
nuclear receptor coactivator 3 isoform a	0	4	0	4
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	7	0	9
Thymidine kinase	0	1	0	1
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Isocitrate lyase	0	1	0	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	7	7
Adenine phosphoribosyltransferase	0	0	9	9
UMP-CMP kinase	0	0	8	8
Electron transfer flavoprotein subunit beta	0	0	10	10
Serine/threonine-protein kinase SULU	0	1	0	1
Ras-related protein Rab-10	0	0	11	11
Cyclin-dependent kinase 10	0	1	3	4
Acyl-CoA dehydrogenase family member 10	0	0	11	11
Serine/threonine-protein kinase N3	0	0	10	10
Protein DBF4 homolog A	0	1	0	1
Spike glycoprotein	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
Transmembrane protease serine 2	0	0	4	4
Voltage-dependent L-type calcium channel subunit alpha-1F	0	6	0	6
Proto-oncogene tyrosine-protein kinase Src	0	3	3	6
Transthyretin	0	1	1	2
Neuronal proto-oncogene tyrosine-protein kinase Src	0	0	0	1
Proto-oncogene tyrosine-protein kinase LCK	0	2	0	2
Procathepsin L	0	0	4	4
Quinolone resistance protein NorA	0	1	0	1
Replicase polyprotein 1a	0	0	4	4
Replicase polyprotein 1ab	0	0	4	4
Cytochrome P450 2A6	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Potassium voltage-gated channel subfamily E member 1	0	2	0	2
Cytochrome P450 2B6	0	3	0	3
Potassium voltage-gated channel subfamily KQT member 1	0	2	0	2
Myelin transcription factor 1	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1S	0	6	0	6
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	3	0	3
Breakpoint cluster region protein	0	1	0	1
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	5	5
Protein cereblon	0	6	4	14
Angiotensin-converting enzyme 2	0	0	4	4
Potassium voltage-gated channel subfamily D member 3	0	2	0	2
NF-kappa-B essential modulator	0	1	0	1
Chain A, Breast cancer type 1 susceptibility protein	1	0	0	1
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
NADH-ubiquinone oxidoreductase chain 4	0	0	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Glutamate receptor 1	2	0	0	2
Glutamate receptor 3	2	0	0	2
Glutamate receptor 4	2	0	0	2
Platelet-activating factor receptor	1	0	0	1
Multidrug resistance-associated protein 1	0	5	1	9
Reverse transcriptase/RNaseH	0	2	2	4
exodeoxyribonuclease V subunit RecD	0	1	0	1
exodeoxyribonuclease V subunit RecB	0	1	0	1
exodeoxyribonuclease V subunit RecC	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	0	5	5
Nuclear receptor subfamily 1 group I member 2	0	0	3	3
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
Chain A, DigA16	0	0	1	1
Chain A, DigA16	0	0	1	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	1
Rap guanine nucleotide exchange factor 4	1	0	0	1
Cereblon isoform 4	0	5	0	5
Insulin-like growth factor-binding protein 5	0	0	1	1
Choline O-acetyltransferase	0	1	0	1
prostaglandin E2 receptor EP2 subtype	1	0	0	1
Solute carrier family 22 member 2	0	3	0	5
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Prostaglandin E2 receptor EP1 subtype	0	2	1	3
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	2	1	3
Prostaglandin F2-alpha receptor	0	0	1	1
Prostaglandin E2 receptor EP4 subtype	0	1	1	2
Prostaglandin E2 receptor EP3 subtype	0	2	1	3
Prostaglandin E2 receptor EP2 subtype	0	2	1	3
Prostacyclin receptor	0	2	1	3
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 7	0	0	0	2
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin E2 receptor EP2 subtype	0	1	1	2
Solute carrier family 22 member 7	0	0	0	1
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Solute carrier family 22 member 11	0	0	0	2
Solute carrier organic anion transporter family member 1B2	0	0	0	1
Solute carrier family 22 member 7	0	0	0	1
Eyes absent homolog 2	0	1	0	1
Amyloid-beta precursor protein	3	3	0	6
Metallo-beta-lactamase VIM-13	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase	0	1	0	1
Beta-lactamase VIM-1	0	1	0	1
Isocitrate dehydrogenase [NADP] cytoplasmic	0	1	0	1
Isocitrate dehydrogenase [NADP], mitochondrial	0	1	0	1
Histone deacetylase 8	0	3	0	3
Leukotriene A-4 hydrolase	0	6	1	7
Androgen receptor	0	3	0	3
Tissue factor	0	3	0	3
Histone deacetylase-like amidohydrolase	0	4	1	5
NAD-dependent protein deacetylase sirtuin-1	0	4	0	4
Histone deacetylase	0	3	0	3
Genome polyprotein	0	1	1	2
thyrotropin-releasing hormone receptor	2	0	0	2
eyes absent homolog 2 isoform a	3	0	0	3
lethal(3)malignant brain tumor-like protein 1 isoform I	1	0	0	1
Flavin reductase (NADPH)	0	0	1	1
Regulatory protein E2	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	3	0	3
DNA topoisomerase 2	0	0	0	2
UDP-glucuronosyltransferase 1A1	0	0	0	1
Serum paraoxonase/arylesterase 1	0	2	0	2
Caspase-3	0	1	0	1
DNA topoisomerase 2-alpha	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	0	0	0	4
Glutamate receptor ionotropic, NMDA 3B	0	0	0	4
Glutamate receptor ionotropic, NMDA 3A	0	0	0	4
Sphingosine 1-phosphate receptor 1	0	0	1	1
RCG53912, isoform CRA_a	0	0	0	1
Sphingosine kinase 1	0	0	0	1
Sphingosine kinase 2	0	1	0	2
Sphingosine kinase 1	0	1	0	2
corticotropin-releasing hormone receptor 2	0	1	1	2
corticotropin releasing factor-binding protein	0	1	1	2
glycogen synthase kinase-3 beta isoform 1	0	0	3	3
5'-nucleotidase	0	1	0	1
Adenosine deaminase	0	0	0	2
Chain A, Uracil Phosphoribosyltransferase	0	1	0	1
Skn7p	0	0	0	1
Vpr	2	0	0	2
Solute carrier family 22 member 8	0	0	0	2
Aromatase	0	3	0	3
HSP40, subfamily A [Plasmodium falciparum 3D7]	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
acid sphingomyelinase	3	0	0	3
Thymidylate synthase	0	7	0	7
Dihydrofolate reductase	0	4	3	7
Aldo-keto reductase family 1 member B1	0	2	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Chain A, probable fosfomycin resistance protein	0	0	1	1
Chain B, probable fosfomycin resistance protein	0	0	1	1
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Equilibrative nucleoside transporter 1	0	1	0	1
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	2	2
Purine nucleoside phosphorylase	0	0	1	2
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Histamine H2 receptor	0	3	2	5
5-hydroxytryptamine receptor 1D	0	0	0	1
Histamine H1 receptor	0	1	4	5
Histamine H1 receptor	0	2	1	3
Metabotropic glutamate receptor 5	0	1	1	2
Histamine H1 receptor	0	2	2	4
Carbonic anhydrase	0	0	0	3
Carbonic anhydrase	0	0	0	4
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	1	0	1
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Carbonic anhydrase	0	0	0	4
Solute carrier family 22 member 1	0	1	0	3
Carbonic anhydrase	0	0	0	4
Equilibrative nucleoside transporter 4	0	0	0	1
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 4	0	0	0	1
Carbonic anhydrase 13	0	2	0	4
Histamine H4 receptor	0	1	2	3
Carboxylic ester hydrolase	0	0	0	1
Solute carrier family 22 member 2	0	1	0	2
Histamine H3 receptor	0	1	2	3
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Stromelysin-1	0	0	2	2
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Urease subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Urease subunit beta	0	1	0	1
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
DNA polymerase III, partial	3	0	0	3
hexokinase-4 isoform 1	1	0	0	1
D(1A) dopamine receptor	3	0	0	3
glucokinase regulatory protein	1	0	0	1
tumor susceptibility gene 101 protein	1	0	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Cytochrome P450 2C8	0	2	0	3
Cytochrome P450 3A5	0	3	0	4
Oxysterols receptor LXR-beta	0	1	0	1
Tyrosine-protein kinase JAK2	0	0	1	1
Glycogen synthase kinase-3 beta	0	1	0	1
pyruvate kinase	3	0	0	3
[Tau protein] kinase	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Malate dehydrogenase	0	1	0	1
G2/mitotic-specific cyclin-B	0	1	0	1
Endothelin receptor type B	1	0	0	1
Kit ligand	0	1	0	1
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
G1/S-specific cyclin-D1	0	3	0	3
Endothelin-1 receptor	1	0	0	1
Cyclin-dependent kinase 20	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Chain A, Acetylcholinesterase	0	1	0	1
interferon gamma precursor	0	0	0	3
Interstitial collagenase	0	1	0	1
Acetylcholinesterase	0	1	0	1
Muscarinic acetylcholine receptor M4	0	4	0	4
Alpha-2C adrenergic receptor	0	2	0	2
Multidrug and toxin extrusion protein 2	0	2	0	2
Chain A, beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Chain A, Beta-galactosidase	0	1	0	1
Beta-galactosidase	0	1	0	1
DNA-binding protein Ikaros	0	0	1	4
DNA damage-binding protein 1	0	2	1	3
Zinc finger protein Aiolos	0	0	1	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	2	0	2
Intestinal-type alkaline phosphatase	0	2	0	2
Large neutral amino acids transporter small subunit 1	0	4	0	5
Proton-coupled amino acid transporter 1	0	1	0	2
Phospholipase A-2-activating protein	0	2	0	2
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Chain A, Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplast	0	1	0	1
Cationic amino acid transporter 3	0	1	0	1
Alpha-mannosidase 2C1	0	1	0	1
Fucose-binding lectin PA-IIL	0	1	0	1
CD209 antigen	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Dihydrofolate reductase	0	6	0	7
Dipeptidyl peptidase 4	0	3	0	3
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	3	0	3
Thymidylate synthase	0	2	0	2
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	3	0	4
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	3	0	4
Thymidylate synthase	0	4	0	4
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	1	0	2
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	3	0	3
5-hydroxytryptamine receptor 2A	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	3	0	3
Dihydrofolate reductase	0	3	0	3
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	3	0	3
Bifunctional purine biosynthesis protein ATIC	0	4	0	4
Delta-type opioid receptor	0	2	0	2
Mu-type opioid receptor	0	3	0	3
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	4	0	4
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Caspase-7	1	0	0	1
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	3	0	3
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	1	0	2
Trifunctional purine biosynthetic protein adenosine-3	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	4	0	5
Glucocorticoid receptor	0	6	2	13
Glycine receptor subunit alpha-1	0	6	0	6
Androgen receptor	0	4	0	4
Glycine receptor subunit beta	0	6	0	6
Glycine receptor subunit alpha-2	0	6	0	6
Glycine receptor subunit alpha-3	0	6	0	6
Chain A, Probable serine/threonine-protein kinase pknB	0	1	0	1
nonstructural protein 1	0	1	0	1
LANA	0	0	0	1
phospholipase A2, group III	0	1	0	1
histone-lysine N-methyltransferase NSD2 isoform 1	0	0	0	1
protein AF-9 isoform a	0	0	0	1
dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Aldo-keto reductase family 1 member B1	0	3	0	3
Muscarinic acetylcholine receptor M2	0	2	0	2
Muscarinic acetylcholine receptor M1	0	2	0	2
Angiotensin-converting enzyme	0	2	0	2
Sodium-dependent noradrenaline transporter	0	2	0	2
Guanine nucleotide-binding protein G	1	0	0	1
NEDD8-activating enzyme E1 regulatory subunit	0	0	1	1
Nuclear receptor subfamily 3 group C member 3	0	2	0	2
NEDD8-activating enzyme E1 catalytic subunit	0	0	1	1
P2Y purinoceptor 12	0	1	0	1
phosphoglycerate kinase	1	0	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Nuclear receptor corepressor 1	0	3	0	3
Integrin beta-1	0	1	0	1
Integrin alpha-4	0	1	0	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	2	0	2
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD(+) hydrolase SARM1	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	3	0	3
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	3	0	3
NAD-dependent protein deacetylase	0	1	0	1
BRCA1	1	0	0	1
histone deacetylase 9 isoform 3	2	0	0	2
C-terminal-binding protein 1	1	0	0	1
Protein Tat	0	0	2	2
NAD-dependent protein deacetylase sirtuin-7	0	1	0	1
Luciferin 4-monooxygenase	0	1	1	2
Amine oxidase [flavin-containing] B	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 2	0	1	0	1
Dual specificity mitogen-activated protein kinase kinase 1	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Chain A, Thymidylate Synthase	0	1	0	1
Serine hydroxymethyltransferase, cytosolic	0	1	1	2
Thymidylate synthase	0	2	0	2
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
SLC16A10 protein	0	0	0	2
Monocarboxylate transporter 10	0	0	0	2
Estrogen receptor 1	0	1	0	1
fMet-Leu-Phe receptor	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Cyclooxygenase-2	0	1	0	1
Growth factor receptor-bound protein 2	0	0	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	0	0	1
Coiled-coil domain-containing protein 6	0	1	0	1
luciferase	0	0	0	1
Estrogen receptor	0	2	0	2
Progesterone receptor	0	2	0	3
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Corticosteroid-binding globulin	0	1	0	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Estrogen receptor beta	0	2	0	2
Chain A, Thymidylate Synthase	0	1	0	1
Chain B, Thymidylate Synthase	0	1	0	1
Chain A, THYMIDYLATE SYNTHASE	0	1	0	1
Chain A, THYMIDYLATE SYNTHASE	0	1	0	1
NS5	0	0	1	1
Polymerase basic protein 2	0	0	1	1
RNA-directed RNA polymerase catalytic subunit	0	0	1	1
Polymerase acidic protein	0	0	2	2
Adenosylhomocysteinase	0	0	0	2
Adenosine receptor A1	0	1	0	1
Genome polyprotein	0	0	1	1
Low-density lipoprotein receptor	0	1	0	1
Fibronectin	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Multidrug resistance-associated protein 1	0	1	0	1
Proprotein convertase subtilisin/kexin type 9	0	1	0	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Albumin	0	2	1	3
Tyrosine-protein phosphatase YopH	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 1	0	1	0	3
Estrogen receptor	0	0	0	1
Cystathionine gamma-lyase	0	1	0	1
Carbonic anhydrase	0	1	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
Serine/threonine-protein kinase haspin	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	1	3
Eukaryotic translation initiation factor 4E	0	0	1	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	4	2	6
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	2	2
Peptidyl-prolyl cis-trans isomerase FKBP5	0	2	0	2
Programmed cell death protein 4	0	0	1	1
Serine/threonine-protein kinase mTOR	0	1	0	1
Solute carrier organic anion transporter family member 1B1	0	4	0	4
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, Mitogen-activated protein kinase 14	0	0	1	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
Chain A, VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2	0	1	0	1
melanocortin receptor 4	0	1	1	2
Platelet-derived growth factor receptor beta	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Cyclin-C	0	1	1	2
Serine/threonine-protein kinase B-raf	0	1	0	1
Delta-type opioid receptor	0	1	1	2
Bifunctional epoxide hydrolase 2	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Vascular endothelial growth factor receptor 3	0	1	0	1
Vascular endothelial growth factor receptor 2	0	1	0	1
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 6	0	1	0	1
Protein delta homolog 1	0	1	1	2
Vascular endothelial growth factor receptor 2	0	1	0	1
Poly [ADP-ribose] polymerase tankyrase-2	0	0	1	1
RuvB-like 2	0	1	1	2
RuvB-like 1	0	1	0	1
C-X-C chemokine receptor type 5 isoform 1	0	1	0	1
ubiquitin-conjugating enzyme E2 N	0	1	0	1
C-C chemokine receptor type 6	0	1	0	1
apelin receptor	0	1	0	1
bcl-2-related protein A1	0	1	0	1
streptokinase A precursor	0	0	1	1
Endoglycoceramidase II	0	0	0	1
Protein kinase C alpha type	0	1	0	1
Estrogen receptor	0	0	1	1
Protein kinase C delta type	0	1	0	1
Protein kinase C epsilon type	0	1	0	1
Protein kinase C zeta type	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	0	1
Protein kinase C gamma type	0	1	0	1
Protein kinase C beta type	0	1	0	1
Estrogen receptor beta	0	0	1	1
Protein kinase C eta type	0	1	0	1
Protein kinase C theta type	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	1	0	3
UDP-glucuronosyltransferase 1A4	0	0	0	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Ras guanyl-releasing protein 3	0	0	1	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	1	0	1
Alpha-1A adrenergic receptor	0	5	0	5
Cytochrome P450 2B1	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
60 kDa chaperonin	0	1	0	1
Retinoic acid receptor alpha	0	2	2	7
60 kDa heat shock protein, mitochondrial	0	1	0	1
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
5-hydroxytryptamine receptor 1A	0	5	0	5
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Alpha-1D adrenergic receptor	0	2	0	2
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
10 kDa heat shock protein, mitochondrial	0	1	0	1
Cellular retinoic acid-binding protein 1	0	0	1	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Thiosulfate sulfurtransferase	0	1	0	1
60 kDa chaperonin	0	1	0	1
10 kDa chaperonin	0	1	0	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Chain A, CHORISMATE MUTASE	0	1	0	1
Chain A, TYROSYL-tRNA SYNTHETASE	0	0	1	1
Tubulin--tyrosine ligase	0	1	0	1
Taste receptor type 2 member 14	0	0	0	1
Chain A, Bacterial leucyl aminopeptidase	0	1	0	1
beta-2 adrenergic receptor	1	0	0	1
Aminopeptidase B	0	2	0	2
M1 family aminopeptidase	0	2	0	2
Cytosol aminopeptidase	0	2	0	2
Phospholipase A2, membrane associated	0	1	0	1
Aminopeptidase N	0	2	0	2
Aminopeptidase N	0	3	0	3
Aminopeptidase N	0	1	0	1
Interleukin-1 receptor antagonist protein	0	1	0	1
Cytosol aminopeptidase	0	2	0	2
Angiotensin-converting enzyme	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
Puromycin-sensitive aminopeptidase	0	1	0	1
Aminopeptidase N	0	2	0	2
Leucyl-cystinyl aminopeptidase	0	1	0	1
Bacterial leucyl aminopeptidase	0	2	0	2
Leukotriene B4 receptor 1	0	1	0	1
Solute carrier family 15 member 2	0	1	0	1
Endoplasmic reticulum aminopeptidase 2	0	1	0	1
Aminopeptidase B	0	1	0	1
Endoplasmic reticulum aminopeptidase 1	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Cocaine esterase	0	1	0	1
UDP-glucuronosyltransferase 1A9	0	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
Glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M2	0	0	1	1
Alpha-2A adrenergic receptor	0	2	0	2
Catechol O-methyltransferase	0	1	0	1
Potassium voltage-gated channel subfamily A member 3	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	0	2
Sodium-dependent serotonin transporter	0	2	0	2
D(3) dopamine receptor	0	2	0	2
5-hydroxytryptamine receptor 7	0	1	0	1
Chloroquine resistance transporter	0	1	0	1
Adenosylhomocysteinase	0	1	0	1
RNA-directed RNA polymerase	0	1	1	2
Sterol 14-alpha-demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol side-chain cleavage enzyme, mitochondrial	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Cytochrome P450 144	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Steroid C26-monooxygenase	0	0	1	1
Sterol 14-alpha demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
14-alpha sterol demethylase	0	0	1	1
Cholesterol 24-hydroxylase	0	2	1	3
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Chain A, Histone deacetylase-like amidohydrolase	0	1	0	1
Nrf2	1	0	0	1
cystic fibrosis transmembrane conductance regulator ATP-binding cassette sub-family C member 7	0	0	0	1
Histone deacetylase	0	1	0	1
Lysine-specific demethylase 4E	0	1	0	1
Gli1	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
protein Wnt-3a precursor	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	1	0	0	1
Histone deacetylase 1	0	2	0	2
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	0	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	0	0	1
Cannabinoid receptor 1	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Delta-type opioid receptor	0	1	0	1
Platelet-activating factor acetylhydrolase	0	1	0	1
Histone deacetylase 1	0	1	0	1
Histone deacetylase	0	1	0	1
Renin	0	1	0	1
Histone deacetylase 3	0	1	0	1
Histone deacetylase	0	1	0	1
HD2 type histone deacetylase HDA106	0	2	0	2
Carboxypeptidase B2	0	1	0	1
Histone deacetylase 7	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase 4	0	1	0	1
REST corepressor 3	0	1	0	1
Histone deacetylase 6	0	1	0	1
Histone deacetylase	0	1	0	1
Beta-1 adrenergic receptor	0	1	0	1
Aurora kinase A	0	1	0	1
Receptor-interacting serine/threonine-protein kinase 1	0	1	0	1
Aurora kinase B-A	0	1	0	1
Aurora kinase A-interacting protein	0	1	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (839)

Protein Targets (1,742)

Ph 1 Chromosome

Synonyms(3)

Research Excerpts

Overview

Treatment

Research

Studies (839)

Drugs Studied (194)

Protein Targets (1,742)