Page last updated: 2024-09-27

Fibrous Histiocytoma of Tendon Sheath

Synonyms(6)

Synonym
Nodular Tenosynovitis
Localized Pigmented Villonodular Synovitis
Tenosynovial Giant Cell Tumor
Localized Giant Cell Tumor of the Tendon Sheath
Fibrous Histiocytoma of Tendon Sheath
Localized Nodular Tenosynovitis

Research Excerpts

Overview

ExcerptReference
"Tenosynovial giant cell tumors are a group of slowly growing benign neoplasms of synovial membrane of joints, tendons, and bursae."( Elsherif, MA; Spinner, RJ; Vaubel, RA; Wenger, DE, 2016)
"Diffuse-type tenosynovial giant cell tumor is a locally aggressive neoplasm that typically involves the knee and hip but rarely involves the shoulder."( Lin, J; Tang, K; Wang, L; Zheng, X, 2019)
"Tenosynovial giant cell tumor is a rare proliferative tumor that arises from the synovium, bursae, or tendon sheaths due to an overproduction of colony-stimulating factor 1."( Lazaridis, D; Monestime, S, 2020)
"Tenosynovial giant cell tumor is the common term used to describe a group of soft-tissue tumors that share a common etiologic link."( Córdoba-Fernández, A; Lobo-Martín, A; Sánchez-Robles, LJ, 2021)

Research

Studies (50)

TimeframeStudies, This Condition (%)All Conditions %
pre-19900 (0.00)23.3326
1990's0 (0.00)12.5806
2000's0 (0.00)18.1394
2010's15 (30.00)28.8240
2020's35 (70.00)9.53
DrugIndicatedRelationship StrengthStudiesTrials
formaldehyde0low10
mitoxantrone0low10
pyranoprofen0medium11
methylene blue0low10
xanthenes0low10
pyrroles0medium172
indazoles0low10
alpha-aminopyridine0medium193
gadolinium0low10
fluorodeoxyglucose f180low40
imatinib mesylate0low40
gefitinib0low10
s 10330medium21
pazopanib0low10
jnj 283121410low10
pexidartinib0medium223
gallium ga 68 dotatate0low10

Protein Targets (805)

ProteinPotency MeasurementsInhibition MeasurementsActivation MeasurementsDrugs
AR protein6006
retinoic acid nuclear receptor alpha variant 14004
estrogen nuclear receptor alpha6006
thyroid stimulating hormone receptor3003
thyroid hormone receptor beta isoform 25005
Voltage-dependent calcium channel gamma-2 subunit5005
Heat shock protein HSP 90-alpha0022
Botulinum neurotoxin type A 0101
Neutrophil cytosol factor 10101
Glutamate receptor 25005
Nitric oxide synthase, endothelial0101
Nitric oxide synthase, brain0202
Nitric oxide synthase, brain 0101
Nitric oxide synthase, inducible0101
Kappa-type opioid receptor0011
Phosphatidylinositol 4-kinase alpha0101
Mu-type opioid receptor0011
Tyrosine-protein kinase 0011
Phosphatidylinositol 4-kinase type 2-beta0101
Phosphatidylinositol 4-kinase type 2-alpha0101
Phosphatidylinositol 4-kinase beta0134
Leukotriene C4 synthase0033
acetylcholinesterase4004
RAR-related orphan receptor gamma3003
Fumarate hydratase6006
TDP1 protein6006
GLI family zinc finger 34004
Microtubule-associated protein tau2002
caspase 7, apoptosis-related cysteine protease2002
estrogen receptor 2 (ER beta)4004
nuclear receptor subfamily 1, group I, member 34004
progesterone receptor4004
EWS/FLI fusion protein4004
retinoid X nuclear receptor alpha4004
estrogen-related nuclear receptor alpha4004
farnesoid X nuclear receptor4004
pregnane X nuclear receptor4004
cytochrome P450 2D63003
polyprotein6006
caspase-32002
aryl hydrocarbon receptor4004
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a4004
Caspase-71001
vitamin D3 receptor isoform VDRA2002
potassium voltage-gated channel subfamily H member 2 isoform d1001
caspase-31001
epidermal growth factor receptor isoform a precursor1102
tyrosine-protein kinase Yes3003
nuclear factor erythroid 2-related factor 2 isoform 14004
geminin4004
peripheral myelin protein 222002
lamin isoform A-delta102002
Bone morphogenetic protein receptor type-1B0044
Cell division cycle 7-related protein kinase0033
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform0134
Serine/threonine-protein kinase PLK40044
Serine/threonine-protein kinase 250033
ATP-dependent RNA helicase DDX3X0044
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta0033
Pyridoxal kinase0044
Citron Rho-interacting kinase0044
Serine/threonine-protein kinase RIO30044
Dual specificity mitogen-activated protein kinase kinase 70033
Serine/threonine-protein kinase Chk10044
Inhibitor of nuclear factor kappa-B kinase subunit beta0033
Peripheral plasma membrane protein CASK0033
Aurora kinase A0044
Cyclin-G-associated kinase0145
Serine/threonine-protein kinase DCLK10033
Inhibitor of nuclear factor kappa-B kinase subunit alpha0033
Muscle, skeletal receptor tyrosine-protein kinase0033
Ephrin type-B receptor 60044
Peroxisomal acyl-coenzyme A oxidase 30044
Mitogen-activated protein kinase 130033
Polyunsaturated fatty acid lipoxygenase ALOX15B2002
ATP-binding cassette sub-family C member 30303
Multidrug resistance-associated protein 40303
3-phosphoinositide-dependent protein kinase 10033
Mitogen-activated protein kinase kinase kinase 130033
Death-associated protein kinase 30033
Mitogen-activated protein kinase kinase kinase 70033
Receptor-interacting serine/threonine-protein kinase 20044
Mitotic checkpoint serine/threonine-protein kinase BUB10044
NUAK family SNF1-like kinase 10033
Dynamin-like 120 kDa protein, mitochondrial0044
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma0033
Tyrosine-protein kinase JAK20033
Rho-associated protein kinase 20044
Serine/threonine-protein kinase ULK10044
Serine/threonine-protein kinase/endoribonuclease IRE10044
Ribosomal protein S6 kinase alpha-50044
U5 small nuclear ribonucleoprotein 200 kDa helicase0044
Ribosomal protein S6 kinase alpha-40044
Serine/threonine-protein kinase 160044
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma0033
Serine/threonine-protein kinase PAK 30033
Cyclin-dependent kinase-like 50033
Serine/threonine-protein kinase 17B0033
Serine/threonine-protein kinase 100044
Serine/threonine-protein kinase D30044
Cyclin-dependent kinase 140033
Bile salt export pump0303
Structural maintenance of chromosomes protein 20044
Mitogen-activated protein kinase kinase kinase 60044
Serine/threonine-protein kinase OSR10033
Mitogen-activated protein kinase kinase kinase kinase 40044
Serine/threonine-protein kinase LATS10044
Serine/threonine-protein kinase PAK 40044
Serine/threonine-protein kinase Chk20033
Tyrosine-protein kinase ABL105510
Epidermal growth factor receptor0459
RAF proto-oncogene serine/threonine-protein kinase0134
Receptor tyrosine-protein kinase erbB-20235
High affinity nerve growth factor receptor0145
Cellular tumor antigen p534004
Guanine nucleotide-binding protein G(i) subunit alpha-20033
ADP/ATP translocase 20044
Cytochrome P450 1A20202
Cytochrome P450 2E10101
Protein kinase C beta type0044
Insulin receptor0145
Tyrosine-protein kinase Lck0347
Tyrosine-protein kinase Fyn0145
Cyclin-dependent kinase 10145
Glycogen phosphorylase, liver form0044
Tyrosine-protein kinase Fes/Fps0044
Macrophage colony-stimulating factor 1 receptor0437
Adenine phosphoribosyltransferase0011
Tyrosine-protein kinase Yes0044
Tyrosine-protein kinase Lyn0145
Proto-oncogene tyrosine-protein kinase receptor Ret0145
Insulin-like growth factor 1 receptor0044
ATP-dependent translocase ABCB10213
Signal recognition particle receptor subunit alpha0044
Cytochrome c1, heme protein, mitochondrial0044
Hepatocyte growth factor receptor0145
Tyrosine-protein kinase HCK0246
Proto-oncogene tyrosine-protein kinase ROS0134
Platelet-derived growth factor receptor beta0347
Tyrosine-protein kinase Fgr0033
Quinolone resistance protein NorA0101
Wee1-like protein kinase 20033
Uncharacterized serine/threonine-protein kinase SBK30033
Serine/threonine-protein kinase A-Raf0044
Cytochrome P450 2C80102
Mast/stem cell growth factor receptor Kit0549
Glycogen phosphorylase, brain form0044
Breakpoint cluster region protein0257
Serine/threonine-protein kinase pim-10044
Fibroblast growth factor receptor 10145
DNA topoisomerase 2-alpha0146
Myosin light chain kinase, smooth muscle0022
Cyclin-dependent kinase 40044
ADP/ATP translocase 30044
Inosine-5'-monophosphate dehydrogenase 20044
Proto-oncogene tyrosine-protein kinase Src0347
cAMP-dependent protein kinase type II-alpha regulatory subunit0044
Insulin receptor-related protein0033
Serine/threonine-protein kinase B-raf0145
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform0044
Ribosyldihydronicotinamide dehydrogenase [quinone]0145
Platelet-derived growth factor receptor alpha0448
Tyrosine-protein kinase Fer0044
Protein kinase C alpha type0044
cAMP-dependent protein kinase catalytic subunit alpha0044
Vascular endothelial growth factor receptor 1 0134
General transcription and DNA repair factor IIH helicase subunit XPD0044
Interferon-induced, double-stranded RNA-activated protein kinase0033
Casein kinase II subunit alpha'0145
Ras-related protein Rab-6A0033
Serine/threonine-protein kinase MAK0033
Cyclin-dependent kinase 11B0033
Ephrin type-A receptor 10044
Fibroblast growth factor receptor 20134
Receptor tyrosine-protein kinase erbB-30134
Multifunctional protein ADE20044
Fibroblast growth factor receptor 40033
Fibroblast growth factor receptor 30033
cAMP-dependent protein kinase catalytic subunit gamma0044
cAMP-dependent protein kinase catalytic subunit beta0044
Ferrochelatase, mitochondrial0044
Ribosomal protein S6 kinase beta-10044
Tyrosine-protein kinase JAK10044
Sodium-dependent dopamine transporter0101
Protein kinase C eta type0033
Cyclin-dependent kinase 20145
Beta-adrenergic receptor kinase 10044
Cruzipain0202
Probable ATP-dependent RNA helicase DDX60044
Activin receptor type-2A0033
Mitogen-activated protein kinase 3 0044
MAP/microtubule affinity-regulating kinase 30044
Deoxycytidine kinase0044
Mitogen-activated protein kinase 10044
Ephrin type-A receptor 20145
Ephrin type-A receptor 30033
Ephrin type-A receptor 80033
Ephrin type-B receptor 20044
Leukocyte tyrosine kinase receptor0033
Non-receptor tyrosine-protein kinase TYK20044
UMP-CMP kinase 0022
Phosphatidylethanolamine-binding protein 10033
Wee1-like protein kinase0044
Heme oxygenase 20044
Tyrosine-protein kinase receptor UFO0134
Mitogen-activated protein kinase 40033
S-adenosylmethionine synthase isoform type-20033
DnaJ homolog subfamily A member 10044
RAC-alpha serine/threonine-protein kinase0145
RAC-beta serine/threonine-protein kinase0044
G protein-coupled receptor kinase 40033
Cytochrome P450 2C190202
Dual specificity protein kinase TTK0044
DNA replication licensing factor MCM40044
Type-1 angiotensin II receptor0101
Prostaglandin G/H synthase 20033
Tyrosine-protein kinase receptor Tie-10033
Vascular endothelial growth factor receptor 30134
Vascular endothelial growth factor receptor 20336
Dual specificity mitogen-activated protein kinase kinase 20044
Receptor-type tyrosine-protein kinase FLT30347
Bone morphogenetic protein receptor type-1A0044
Activin receptor type-1B0044
TGF-beta receptor type-10044
Serine/threonine-protein kinase receptor R30033
TGF-beta receptor type-20044
Electron transfer flavoprotein subunit beta0011
Tyrosine-protein kinase CSK0044
Glycine--tRNA ligase0044
Mitogen-activated protein kinase kinase kinase 80101
Protein kinase C iota type0044
Exosome RNA helicase MTR40044
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform0134
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform0134
Serine/threonine-protein kinase mTOR0134
Megakaryocyte-associated tyrosine-protein kinase0033
Tyrosine-protein kinase Tec0044
Tyrosine-protein kinase TXK0033
Tyrosine-protein kinase ABL20044
Tyrosine-protein kinase FRK0044
G protein-coupled receptor kinase 60044
Tyrosine-protein kinase ZAP-700033
Tyrosine-protein kinase SYK0044
26S proteasome regulatory subunit 6B0044
Mitogen-activated protein kinase 80044
Mitogen-activated protein kinase 90044
Dual specificity mitogen-activated protein kinase kinase 40033
Dual specificity mitogen-activated protein kinase kinase 30044
Histamine H2 receptor2002
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha0044
Casein kinase I isoform alpha0145
Casein kinase I isoform delta0044
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 0134
MAP kinase-activated protein kinase 20044
Cyclin-dependent kinase 80033
Elongation factor Tu, mitochondrial0044
Cysteine--tRNA ligase, cytoplasmic0044
Casein kinase I isoform epsilon0044
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial0044
Dual specificity protein kinase CLK10044
Dual specificity protein kinase CLK20044
Dual specificity protein kinase CLK30033
Glycogen synthase kinase-3 alpha0044
Glycogen synthase kinase-3 beta0044
Cyclin-dependent kinase 70044
Cyclin-dependent kinase 90044
Ras-related protein Rab-27A0044
Tyrosine-protein kinase Blk0134
Interleukin-1 receptor-associated kinase 10044
Ribosomal protein S6 kinase alpha-30044
Cytoplasmic tyrosine-protein kinase BMX0033
cAMP-dependent protein kinase catalytic subunit PRKX0033
Serine/threonine-protein kinase Nek20044
Serine/threonine-protein kinase Nek30044
Serine/threonine-protein kinase Nek40033
Tyrosine-protein kinase JAK30134
Dual specificity mitogen-activated protein kinase kinase 60044
Serine/threonine-protein kinase PLK10033
Death-associated protein kinase 10033
LIM domain kinase 10044
LIM domain kinase 20044
Mitogen-activated protein kinase 120033
Mitogen-activated protein kinase 100044
Tyrosine--tRNA ligase, cytoplasmic0044
5'-AMP-activated protein kinase subunit gamma-10044
5'-AMP-activated protein kinase catalytic subunit alpha-20033
Ephrin type-B receptor 30044
Ephrin type-A receptor 50044
Ephrin type-B receptor 40145
Ephrin type-B receptor 10033
Ephrin type-A receptor 40044
Adenylate kinase 2, mitochondrial0044
Adenosine kinase0044
Beta-secretase 10101
Hormonally up-regulated neu tumor-associated kinase0033
Serine/threonine-protein kinase SIK10033
Receptor-interacting serine/threonine-protein kinase 40033
Spike glycoprotein5005
Ras-related protein Rab-100044
Cell division control protein 2 homolog0033
Actin-related protein 30044
Actin-related protein 20044
Calcium-dependent protein kinase 10033
GTP-binding nuclear protein Ran0044
Tubulin alpha-1A chain0022
Casein kinase II subunit alpha0134
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta0033
SRSF protein kinase 20033
Casein kinase I isoform gamma-20044
DNA-dependent protein kinase catalytic subunit0101
Mitogen-activated protein kinase kinase kinase 90033
Serine/threonine-protein kinase PknB0033
Cyclin-dependent kinase 30044
Cyclin-dependent kinase-like 10033
Cyclin-dependent kinase 60044
Cyclin-dependent-like kinase 5 0044
Cyclin-dependent kinase 160044
Cyclin-dependent kinase 170044
ATP-dependent 6-phosphofructokinase, platelet type0033
Synaptic vesicular amine transporter0101
Protein kinase C epsilon type0033
Dual specificity mitogen-activated protein kinase kinase 10044
Angiopoietin-1 receptor0033
Mitogen-activated protein kinase kinase kinase 100033
DNA topoisomerase 2-beta0045
Transcription factor p650101
Protein kinase C theta type0044
Activin receptor type-10044
Macrophage-stimulating protein receptor0044
Focal adhesion kinase 10044
Protein kinase C zeta type0022
Protein kinase C delta type0044
Tyrosine-protein kinase BTK0145
Tyrosine-protein kinase receptor TYRO30033
Cyclin-dependent kinase 180033
Activated CDC42 kinase 10044
Epithelial discoidin domain-containing receptor 10246
Tyrosine-protein kinase ITK/TSK0033
Myotonin-protein kinase0033
Mitogen-activated protein kinase kinase kinase kinase 20044
Mitogen-activated protein kinase kinase kinase 120033
Tyrosine-protein kinase Mer0044
Serine/threonine-protein kinase 40044
5'-AMP-activated protein kinase catalytic subunit alpha-10044
Serine/threonine-protein kinase PAK 10033
Dual specificity mitogen-activated protein kinase kinase 50044
Mitogen-activated protein kinase 70044
Serine/threonine-protein kinase PAK 20033
Serine/threonine-protein kinase 30044
Mitogen-activated protein kinase kinase kinase 10044
cGMP-dependent protein kinase 20033
Integrin-linked protein kinase0044
Rho-associated protein kinase 10044
Non-receptor tyrosine-protein kinase TNK10044
Serine/threonine-protein kinase PRP4 homolog0033
Receptor-interacting serine/threonine-protein kinase 10145
Calcium/calmodulin-dependent protein kinase type II subunit beta0033
Calcium/calmodulin-dependent protein kinase type II subunit gamma0044
Calcium/calmodulin-dependent protein kinase type II subunit delta0044
Dual specificity tyrosine-phosphorylation-regulated kinase 1A0044
Activin receptor type-2B0044
Bone morphogenetic protein receptor type-20044
Protein-tyrosine kinase 60044
cGMP-dependent protein kinase 1 0044
Cyclin-dependent kinase 130044
Calcium/calmodulin-dependent protein kinase type 10033
Inhibitor of nuclear factor kappa-B kinase subunit epsilon0044
Protein-tyrosine kinase 2-beta0044
Maternal embryonic leucine zipper kinase0044
Structural maintenance of chromosomes protein 1A0044
Chromodomain-helicase-DNA-binding protein 40044
Peroxisomal acyl-coenzyme A oxidase 10033
Serine/threonine-protein kinase D10033
Serine/threonine-protein kinase 380033
Receptor tyrosine-protein kinase erbB-40134
Ribosomal protein S6 kinase alpha-20033
Ephrin type-A receptor 70044
Delta(24)-sterol reductase0044
Ribosomal protein S6 kinase alpha-10044
Dual specificity testis-specific protein kinase 10044
Myosin light chain kinase, smooth muscle0044
Mitogen-activated protein kinase 110044
Serine/threonine-protein kinase STK110044
Rhodopsin kinase GRK10033
NT-3 growth factor receptor0033
Serine/threonine-protein kinase N10044
Serine/threonine-protein kinase N20044
Mitogen-activated protein kinase 140055
Calcium/calmodulin-dependent protein kinase type IV0044
Mitogen-activated protein kinase kinase kinase 110044
BDNF/NT-3 growth factors receptor0033
Mitogen-activated protein kinase 60033
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform0033
Discoidin domain-containing receptor 20347
AP2-associated protein kinase 10044
Myosin light chain kinase 30044
Uncharacterized aarF domain-containing protein kinase 50011
Serine/threonine-protein kinase ULK30011
Serine/threonine-protein kinase SBK10033
Mitogen-activated protein kinase kinase kinase 190033
Putative heat shock protein HSP 90-beta 20044
Serine/threonine-protein kinase TNNI3K0033
Leucine-rich repeat serine/threonine-protein kinase 20033
Serine/threonine-protein kinase MRCK alpha0044
Serine/threonine-protein kinase MRCK gamma0044
Acyl-CoA dehydrogenase family member 100044
Serine/threonine-protein kinase Nek50033
Serine/threonine-protein kinase N30033
Serine/threonine-protein kinase ULK30044
Dual serine/threonine and tyrosine protein kinase0033
Mitogen-activated protein kinase kinase kinase 150033
Uncharacterized protein FLJ452520044
Acyl-CoA dehydrogenase family member 110044
Serine/threonine-protein kinase/endoribonuclease IRE20044
Serine/threonine-protein kinase MARK20044
Serine/threonine-protein kinase TAO10044
STE20-related kinase adapter protein alpha0044
Myosin-140033
AarF domain-containing protein kinase 10044
Serine/threonine-protein kinase tousled-like 20033
Serine/threonine-protein kinase 32C0033
Serine/threonine-protein kinase pim-30033
ATP-dependent RNA helicase DDX420033
Serine/threonine-protein kinase VRK20033
Myosin light chain kinase family member 40033
Homeodomain-interacting protein kinase 10033
Calcium/calmodulin-dependent protein kinase type 1D0033
Mitogen-activated protein kinase kinase kinase kinase 30044
Cyclin-dependent kinase-like 30033
MAP kinase-activated protein kinase 50044
Serine/threonine-protein kinase BRSK20033
Serine/threonine-protein kinase NIM10033
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B0011
Serine/threonine-protein kinase ULK20033
Misshapen-like kinase 10033
Serine/threonine-protein kinase DCLK20033
Calcium/calmodulin-dependent protein kinase kinase 10033
Casein kinase I isoform alpha-like0033
Homeodomain-interacting protein kinase 40033
Myosin-IIIa0033
Ankyrin repeat and protein kinase domain-containing protein 10033
Serine/threonine-protein kinase Nek110033
Atypical kinase COQ8A, mitochondrial0044
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma0044
Mitogen-activated protein kinase 150044
Serine/threonine-protein kinase Nek90044
Serine/threonine-protein kinase BRSK10033
Serine/threonine-protein kinase 350033
Serine/threonine-protein kinase Nek70033
Rhodopsin kinase GRK70033
Serine/threonine-protein kinase 32A0033
Myosin-IIIb0033
ATP-dependent RNA helicase DDX10044
Dual specificity tyrosine-phosphorylation-regulated kinase 20033
Cyclin-dependent kinase-like 20033
Canalicular multispecific organic anion transporter 10303
Mitogen-activated protein kinase kinase kinase kinase 10044
Serine/threonine-protein kinase Sgk30033
Atypical kinase COQ8B, mitochondrial0033
Aurora kinase B0145
MAP/microtubule affinity-regulating kinase 40044
Calcium/calmodulin-dependent protein kinase type 1G0033
Serine/threonine-protein kinase Nek10044
Cyclin-dependent kinase 150033
PAS domain-containing serine/threonine-protein kinase0033
Calcium/calmodulin-dependent protein kinase kinase 20044
EKC/KEOPS complex subunit TP53RK0044
SRSF protein kinase 10033
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase0044
Mitogen-activated protein kinase kinase kinase 50044
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha0033
Mitogen-activated protein kinase kinase kinase 30044
Eukaryotic translation initiation factor 2-alpha kinase 10044
Serine/threonine-protein kinase RIO10033
MAP kinase-interacting serine/threonine-protein kinase 10033
Serine/threonine-protein kinase RIO20033
Cyclin-dependent kinase 190033
Transient receptor potential cation channel subfamily M member 60033
Testis-specific serine/threonine-protein kinase 10033
Serine/threonine-protein kinase 330033
Nucleolar GTP-binding protein 10044
Serine/threonine-protein kinase D20044
Serine/threonine-protein kinase DCLK30033
NUAK family SNF1-like kinase 20044
RNA cytidine acetyltransferase0044
Serine/threonine-protein kinase SIK20044
Myosin light chain kinase 2, skeletal/cardiac muscle0033
STE20-like serine/threonine-protein kinase 0044
Serine/threonine-protein kinase TAO30044
Homeodomain-interacting protein kinase 20033
Tyrosine-protein kinase Srms0033
Homeodomain-interacting protein kinase 30033
Serine/threonine-protein kinase PLK30033
dCTP pyrophosphatase 10044
Dual specificity protein kinase CLK40044
MAP kinase-interacting serine/threonine-protein kinase 20033
Serine/threonine-protein kinase Nek60033
Casein kinase I isoform gamma-10044
Serine/threonine-protein kinase PAK 60033
SNF-related serine/threonine-protein kinase0033
Serine/threonine-protein kinase LATS20033
Serine/threonine-protein kinase 360033
Phenylalanine--tRNA ligase beta subunit0044
Isoleucine--tRNA ligase, mitochondrial0033
BMP-2-inducible protein kinase0044
Obg-like ATPase 10033
Midasin0044
Interleukin-1 receptor-associated kinase 40044
Serine/threonine-protein kinase 32B0033
Mitogen-activated protein kinase kinase kinase 200044
Cyclin-dependent kinase 120044
Serine/threonine-protein kinase PLK20033
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 130044
Serine/threonine-protein kinase MARK10033
Serine/threonine-protein kinase pim-20044
Serine/threonine-protein kinase PAK 50033
Serine/threonine-protein kinase 260044
eIF-2-alpha kinase GCN20033
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial0044
Serine/threonine-protein kinase NLK0044
Serine/threonine-protein kinase 17A0033
STE20/SPS1-related proline-alanine-rich protein kinase0033
Ephrin type-A receptor 60033
5'-AMP-activated protein kinase subunit gamma-20044
Serine/threonine-protein kinase TBK10044
Septin-90044
Death-associated protein kinase 20033
Ribosomal protein S6 kinase alpha-60044
TRAF2 and NCK-interacting protein kinase0044
Serine/threonine-protein kinase tousled-like 10033
Serine/threonine-protein kinase TAO20044
Long-chain-fatty-acid--CoA ligase 50033
ALK tyrosine kinase receptor0044
Broad substrate specificity ATP-binding cassette transporter ABCG20315
SRSF protein kinase 30033
Serine/threonine-protein kinase ICK0044
Cyclin-dependent kinase 11A0033
Aurora kinase C0033
Calcium/calmodulin-dependent protein kinase type II subunit alpha0033
RAC-gamma serine/threonine-protein kinase0044
Serine/threonine-protein kinase 38-like0044
Microtubule-associated serine/threonine-protein kinase 10033
Serine/threonine-protein kinase SIK30044
Mitogen-activated protein kinase kinase kinase 20044
Thyroid hormone receptor-associated protein 30022
Dual specificity tyrosine-phosphorylation-regulated kinase 1B0033
Mitogen-activated protein kinase kinase kinase kinase 50044
Receptor-interacting serine/threonine-protein kinase 30044
Serine/threonine-protein kinase MRCK beta0044
Interleukin-1 receptor-associated kinase 30044
Serine/threonine-protein kinase 240044
Casein kinase I isoform gamma-30044
Mitogen-activated protein kinase kinase kinase 40044
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE2002
Luciferase3003
glp-1 receptor, partial3003
thioredoxin reductase1001
SMAD family member 23003
SMAD family member 33003
cytochrome P450 family 3 subfamily A polypeptide 44004
glucocorticoid receptor [Homo sapiens]3003
peroxisome proliferator-activated receptor delta3003
IDH13003
parathyroid hormone/parathyroid hormone-related peptide receptor precursor2002
serine/threonine-protein kinase mTOR isoform 12002
DNA polymerase iota isoform a (long)3003
DNA repair protein RAD52 homolog isoform a0003
Cytochrome P450 3A40304
Cytochrome P450 3A50001
ATPase family AAA domain-containing protein 53003
Ataxin-24004
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, CELL DIVISION PROTEIN KINASE 20101
Chain A, Cell Division Protein Kinase 20101
DNA repair and recombination protein RadA0011
G2/mitotic-specific cyclin-B10101
Indoleamine 2,3-dioxygenase 10011
Cyclin-A20101
Cyclin-A10101
PPM1D protein4004
Interferon beta4004
Macrophage colony-stimulating factor 1 receptor0303
Cytochrome P450 2C9 0101
Glucagon receptor0101
Potassium voltage-gated channel subfamily H member 20404
Chain A, TYROSYL-DNA PHOSPHODIESTERASE2002
Chain E, Fibrin beta chain0101
Chain A, Putative fructose-1,6-bisphosphate aldolase1001
Chain A, JmjC domain-containing histone demethylation protein 3A2002
Chain A, 2-oxoglutarate Oxygenase1001
Chain A, ATP-DEPENDENT DNA HELICASE Q12002
Chain A, Ferritin light chain2002
T cell receptor, partial1001
luteinizing hormone receptor1001
integrase, partial0101
chaperonin-containing TCP-1 beta subunit homolog1001
lens epithelium-derived growth factor p750101
phosphopantetheinyl transferase1001
hypoxia-inducible factor 1 alpha subunit1001
Caspase 6, apoptosis-related cysteine peptidase0001
ATAD5 protein, partial2002
TSHR protein1001
Apoptotic peptidase activating factor 10101
thioredoxin glutathione reductase1001
Smad32002
hypothetical protein, conserved2002
isocitrate dehydrogenase 1, partial1001
G2002
luciferase1001
bromodomain adjacent to zinc finger domain 2B2002
peroxisome proliferator activated receptor gamma3003
euchromatic histone-lysine N-methyltransferase 23003
activating transcription factor 61001
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a1001
v-jun sarcoma virus 17 oncogene homolog (avian)1001
Histone H2A.x1001
serine-protein kinase ATM isoform a1001
Bloom syndrome protein isoform 12002
neutrophil cytosol factor 10101
thyroid hormone receptor beta isoform a1001
nuclear factor erythroid 2-related factor 2 isoform 22002
caspase-9 isoform alpha precursor0101
histone deacetylase 9 isoform 31001
heat shock protein beta-11001
huntingtin isoform 22002
pyruvate kinase PKM isoform a1001
DNA polymerase beta1001
mitogen-activated protein kinase 12002
flap endonuclease 12002
caspase-3 isoform a preproprotein0101
protein AF-9 isoform a0002
histone-lysine N-methyltransferase 2A isoform 2 precursor2002
peptidyl-prolyl cis-trans isomerase NIMA-interacting 11001
DNA polymerase eta isoform 12002
urokinase-type plasminogen activator precursor1001
plasminogen precursor1001
urokinase plasminogen activator surface receptor precursor1001
Vpr2002
survival motor neuron protein isoform d2002
muscleblind-like protein 1 isoform 12002
replicative DNA helicase0001
recombinase A0011
POsterior Segregation0011
neuropeptide S receptor isoform A1001
Glutathione reductase0101
Glutathione reductase, mitochondrial0102
Glycoprotein hormones alpha chain2002
HLA class I histocompatibility antigen, B alpha chain 2002
Albumin0001
Amyloid-beta precursor protein1102
Dihydrolipoyl dehydrogenase, mitochondrial0102
Microtubule-associated protein tau0112
Alpha-1B adrenergic receptor0101
Amine oxidase [flavin-containing] A0202
Alpha-1D adrenergic receptor0101
Sodium-dependent noradrenaline transporter 0213
Alpha-synuclein1001
Alpha-1A adrenergic receptor0101
Guanine nucleotide-binding protein G2002
Inositol monophosphatase 12002
TAR DNA-binding protein 431102
Thioredoxin reductase 1, cytoplasmic0102
Dihydrolipoyl dehydrogenase 0102
Inositol hexakisphosphate kinase 12002
Zinc finger protein mex-50011
cytochrome P450 2C9, partial2002
phosphoglycerate kinase2002
ATP-dependent phosphofructokinase2002
Chain A, Probable serine/threonine-protein kinase pknB0101
dopamine D1 receptor1001
15-lipoxygenase, partial1001
WRN1001
USP1 protein, partial1001
NFKB1 protein, partial1001
GLS protein1001
Thrombopoietin1001
apical membrane antigen 1, AMA11001
DNA polymerase III, partial1001
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)1001
regulator of G-protein signaling 41001
nonstructural protein 10101
LANA0001
67.9K protein1001
Parkin1001
arylsulfatase A1001
pyruvate kinase1001
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)1001
phospholipase A2, group III0101
cytochrome P450 2D6 isoform 11001
NPC intracellular cholesterol transporter 1 precursor1001
cellular tumor antigen p53 isoform a1001
interferon gamma precursor0001
atrial natriuretic peptide receptor 1 precursor1001
histone-lysine N-methyltransferase NSD2 isoform 10001
chromobox protein homolog 12002
importin subunit beta-1 isoform 11001
atrial natriuretic peptide receptor 2 precursor1001
ubiquitin carboxyl-terminal hydrolase 2 isoform a1001
ras-related protein Rab-9A1001
snurportin-11001
GTP-binding nuclear protein Ran isoform 11001
dual specificity tyrosine-phosphorylation-regulated kinase 1A0001
rac GTPase-activating protein 1 isoform a0101
DNA polymerase kappa isoform 11001
cytochrome P450 3A4 isoform 11001
M-phase phosphoprotein 81001
histone acetyltransferase KAT2A isoform 12002
muscarinic acetylcholine receptor M11001
pyruvate kinase PKM isoform b1001
Gamma-aminobutyric acid receptor subunit pi1001
Solute carrier family 22 member 20101
Solute carrier family 22 member 1 0101
Voltage-dependent L-type calcium channel subunit alpha-1F0202
5-hydroxytryptamine receptor 40202
Solute carrier family 22 member 30202
Integrin beta-31001
Aldo-keto reductase family 1 member B10202
Muscarinic acetylcholine receptor M20202
Muscarinic acetylcholine receptor M40202
Integrin alpha-IIb1001
Ornithine decarboxylase1001
Cytochrome P450 2D60202
Muscarinic acetylcholine receptor M10202
Polyunsaturated fatty acid lipoxygenase ALOX150101
Angiotensin-converting enzyme0202
DNA topoisomerase 20001
Gamma-aminobutyric acid receptor subunit beta-11001
Gamma-aminobutyric acid receptor subunit delta1001
Gamma-aminobutyric acid receptor subunit gamma-21001
Gamma-aminobutyric acid receptor subunit alpha-51001
Gamma-aminobutyric acid receptor subunit alpha-31001
Gamma-aminobutyric acid receptor subunit gamma-11001
Gamma-aminobutyric acid receptor subunit alpha-21001
5-hydroxytryptamine receptor 2C0202
Gamma-aminobutyric acid receptor subunit alpha-41001
Gamma-aminobutyric acid receptor subunit gamma-31001
Gamma-aminobutyric acid receptor subunit alpha-61001
Multidrug resistance-associated protein 1 0101
Gamma-aminobutyric acid receptor subunit alpha-11001
Gamma-aminobutyric acid receptor subunit beta-31001
Gamma-aminobutyric acid receptor subunit beta-21001
Casein kinase II subunit beta0101
Voltage-dependent L-type calcium channel subunit alpha-1D 0202
NEDD8-activating enzyme E1 regulatory subunit0011
Voltage-dependent L-type calcium channel subunit alpha-1S0202
Voltage-dependent L-type calcium channel subunit alpha-1C0202
Nuclear receptor subfamily 3 group C member 3 0202
Integrase 0101
Multidrug and toxin extrusion protein 20101
Casein kinase II subunit alpha 30101
NEDD8-activating enzyme E1 catalytic subunit0011
GABA theta subunit1001
Multidrug and toxin extrusion protein 10101
Gamma-aminobutyric acid receptor subunit epsilon1001
Single-stranded DNA cytosine deaminase1001
P2Y purinoceptor 120101
Solute carrier organic anion transporter family member 1B30202
2,3-bisphosphoglycerate-independent phosphoglycerate mutase1001
Membrane-associated progesterone receptor component 10033
Acetylcholinesterase0101
Carbonic anhydrase 90202
Receptor protein-tyrosine kinase 0101
Rab-like protein 30033
ATP-dependent RNA helicase DHX300033
Myosin-100022
MAP kinase-activated protein kinase 30011
Carbonic anhydrase 120101
Eukaryotic translation initiation factor 5B0011
Proto-oncogene tyrosine-protein kinase Src0011
Carbonic anhydrase 10101
Carbonic anhydrase 20101
Low-density lipoprotein receptor0101
Fibronectin0101
Carbonic anhydrase 30101
Solute carrier family 2, facilitated glucose transporter member 40101
Potassium voltage-gated channel subfamily E member 10101
Carbonic anhydrase 40101
Carbonic anhydrase 60101
Carbonic anhydrase 5A, mitochondrial0101
Carbonic anhydrase 70101
Potassium voltage-gated channel subfamily KQT member 10101
Ras-related C3 botulinum toxin substrate 10011
Sodium channel protein type 5 subunit alpha0101
Multidrug resistance-associated protein 10101
Proprotein convertase subtilisin/kexin type 90101
Dual specificity testis-specific protein kinase 20011
Carbonic anhydrase 150101
Carbonic anhydrase 130101
Potassium voltage-gated channel subfamily D member 30101
Carbonic anhydrase 140101
Carbonic anhydrase 5B, mitochondrial0101
Chain A, Beta-lactamase1001
Rap guanine nucleotide exchange factor 31001
Amine oxidase [flavin-containing] B0101
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]