c-Met tyrosine kinase inhibitor

An EC 2.7.10.1 (receptor protein-tyrosine kinase) inhibitor that interferes with the action of c-Met tyrosine kinase.

ChEBI ID: 90199

Members (3)

Member	Definition	Class
AMG-208	A member of the class of quinolines that is 7-methoxyquinoline substituted at position 4 by a (6-phenyl[1,2,4]triazolo[4,3-b]pyridazin-3-yl)methoxy group. AMG exhibits antitumour activity, particularly in prostate cancer.	AMG-208
pha 665752	A member of the class of indolones that is 1,3-dihydro-2H-indol-2-one which is substituted by a (2,6-dichlorobenzyl)sulfonyl group at position 5 and by a (1H-pyrrol-2-yl)methylidene group at position 2, the pyrrole ring of which is substituted by methyl groups at positions 3 and 5, and by a [2-(pyrrolidin-1-ylmethyl)pyrrolidin-1-yl]carbonyl group at position 4 (the Z,R isomer).	PHA-665752
sgx 523	A member of the class of triazolopyridazines that is 6-(1-methylpyrazol-4-yl)[1,2,4]triazolo[4,3-b]pyridazine-3-thiol in which the thiol hydrogen is replaced by a quinolin-6-yl group.	SGX-523

Research

Studies (33)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	7 (21.21)	29.6817
2010's	18 (54.55)	24.3611
2020's	8 (24.24)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	1 (2.17%)	5.53%
Reviews	3 (6.52%)	6.00%
Case Studies	0 (0.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	42 (91.30%)	84.16%

Protein Targets (499)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	0.7564	1	1
cytochrome P450 family 3 subfamily A polypeptide 4	Homo sapiens (human)	Potency	0.7564	1	1
EWS/FLI fusion protein	Homo sapiens (human)	Potency	25.2484	2	2
G	Vesicular stomatitis virus	Potency	0.7564	1	1
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	0.7564	1	1
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	0.7564	1	2
Interferon beta	Homo sapiens (human)	Potency	4.1116	2	4
PPM1D protein	Homo sapiens (human)	Potency	5.2300	1	2

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
ALK tyrosine kinase receptor	Homo sapiens (human)	IC50	0.0767	1	3
calcium-dependent protein kinase 4	Plasmodium falciparum 3D7	IC50	0.0210	1	1
Chain A, Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	0.0090	1	2
Chain A, Hepatocyte growth factor receptor	Homo sapiens (human)	Ki	5.0014	1	4
Cyclin-dependent kinase 2-associated protein 2	Homo sapiens (human)	IC50	10.0000	1	1
Cytochrome P450 3A4	Homo sapiens (human)	IC50	32.0000	1	1
Epidermal growth factor receptor	Homo sapiens (human)	IC50	1.0075	2	4
Fibroblast growth factor receptor 1	Homo sapiens (human)	IC50	3.0000	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	10.0000	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	0.0240	17	21
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	IC50	0.1000	1	1
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	IC50	0.1000	1	1
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	IC50	0.1000	1	1
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	IC50	0.1000	1	1
Insulin-like growth factor 1 receptor	Homo sapiens (human)	IC50	10.0000	1	1
Macrophage-stimulating protein receptor	Homo sapiens (human)	IC50	0.0680	1	1
MAP kinase-activated protein kinase 2	Homo sapiens (human)	IC50	10.0000	1	1
MAP kinase-activated protein kinase 3	Homo sapiens (human)	IC50	10.0000	1	1
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	10.0000	1	1
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	IC50	0.0767	1	3
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	6.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50	1.4000	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	0.5315	2	2

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	2
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	10.0000	1	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	17.5775	2	4
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	5.3850	1	2
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	30.0000	1	2
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	30.0000	1	2
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	3
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	2
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
Activin receptor type-1	Homo sapiens (human)	Kd	20.0000	2	4
Activin receptor type-1B	Homo sapiens (human)	Kd	20.0000	2	4
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	1	2
Activin receptor type-2B	Homo sapiens (human)	Kd	20.0000	2	4
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	1	2
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	2
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	1	2
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	2
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	2
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	2
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	6.3500	1	2
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	8.3500	1	2
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	10.0000	1	2
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	17.5800	2	4
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	2
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	2
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	2
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	20.0000	2	4
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	1	2
Aurora kinase A	Homo sapiens (human)	Kd	20.0000	2	4
Aurora kinase B	Homo sapiens (human)	Kd	20.4000	2	5
Aurora kinase C	Homo sapiens (human)	Kd	5.1500	1	2
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	5.4000	1	2
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	20.0094	2	5
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	20.0000	2	4
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	20.0000	2	4
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	19.0500	2	4
Breakpoint cluster region protein	Homo sapiens (human)	Kd	30.0000	1	2
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	10.0000	1	2
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	5.0320	1	2
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	17.5183	2	4
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	6.0500	1	2
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	5.7500	1	2
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	10.0000	1	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	6.7000	1	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	10.0000	1	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	18.2250	2	4
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	18.0000	2	4
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	20.0000	2	4
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	20.0000	2	4
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	20.0000	2	4
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	15.0010	1	2
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	10.0000	1	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	2
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	20.0000	2	4
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	10.0000	1	2
Casein kinase I isoform delta	Homo sapiens (human)	Kd	18.5500	2	4
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	17.7150	2	4
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	20.0000	2	4
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	16.6667	2	3
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	22.0000	2	5
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	10.0000	1	2
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	18.9000	2	4
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	1	2
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	1	2
Choline-phosphate cytidylyltransferase A	Homo sapiens (human)	Kd	30.0000	1	2
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	2
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	20.0000	2	4
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	20.0000	2	4
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	5.6500	1	2
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	5.2550	1	2
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	17.7750	2	4
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	17.7200	2	4
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	5.7500	1	2
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	20.0000	2	4
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	22.0000	2	5
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	13.8133	3	6
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	1	2
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	17.5325	2	4
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	17.9500	2	4
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	6.2000	1	2
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	1	2
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	20.0000	2	4
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	20.0000	2	4
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	17.8250	2	4
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	3
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	1	2
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	2
Death-associated protein kinase 1	Homo sapiens (human)	Kd	10.0000	1	2
Death-associated protein kinase 2	Homo sapiens (human)	Kd	10.0000	1	2
Death-associated protein kinase 3	Homo sapiens (human)	Kd	10.0000	1	2
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	2
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	2
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	19.4000	2	4
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	2
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	2
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	2
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	2
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	17.7750	2	4
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	17.7450	2	4
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	20.0000	2	4
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	16.6667	2	3
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	17.8500	2	4
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	20.0000	2	4
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	1	2
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	17.6825	2	4
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	17.6025	2	4
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	14.5333	2	3
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	20.0000	2	4
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	10.0000	1	2
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
Dual specificity testis-specific protein kinase 2	Homo sapiens (human)	Kd	30.0000	1	2
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	17.6950	2	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	20.3600	2	5
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	10.0000	1	2
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	6.7000	1	2
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	1	2
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	2
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	10.0000	1	2
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	22.0000	2	5
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	10.0000	1	2
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	6.9500	1	2
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	10.0000	1	2
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	20.0000	2	4
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	18.2250	2	4
Epidermal growth factor receptor	Homo sapiens (human)	Kd	11.5385	13	26
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	17.5175	2	4
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)	Kd	30.0000	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	2
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	2
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	20.0000	2	4
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	7.6000	1	2
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	8.8000	2	4
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	10.0000	1	2
Focal adhesion kinase 1	Homo sapiens (human)	Kd	17.9750	2	4
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	5.2100	1	2
G protein-coupled receptor kinase 6	Homo sapiens (human)	Kd	30.0000	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	30.0000	1	2
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	20.0000	2	4
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	20.0000	2	4
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	2
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	1
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	2
Hepatocyte growth factor receptor	Homo sapiens (human)	EC50	0.0420	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	3.7543	4	8
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	13.4400	2	3
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	5.0465	1	2
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	5.0600	1	2
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	5.0315	1	2
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	5.6500	1	2
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	5.7000	1	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	10.0000	1	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	1	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	17.6750	2	4
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	2
Insulin receptor	Homo sapiens (human)	Kd	18.0750	2	4
Insulin receptor-related protein	Homo sapiens (human)	Kd	6.7500	1	2
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	20.0000	2	4
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	2
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	17.9000	2	4
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	17.6525	2	4
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	18.1250	2	4
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	4
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	10.0000	1	2
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	10.0000	1	2
LIM domain kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
LIM domain kinase 2	Homo sapiens (human)	Kd	20.0000	2	4
Long-chain-fatty-acid--CoA ligase 5	Homo sapiens (human)	Kd	30.0000	1	3
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	5.3500	1	2
Macrophage-stimulating protein receptor	Homo sapiens (human)	EC50	0.9000	1	1
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	18.0000	2	4
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	20.0000	2	4
MAP kinase-activated protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	1
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	20.0000	2	4
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	1	2
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	10.0000	1	2
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	20.0000	2	4
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	20.0000	2	4
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	7.0681	8	16
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	20.0000	2	4
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	2
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	20.0000	2	4
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	1	2
Midasin	Homo sapiens (human)	Kd	30.0000	1	2
Misshapen-like kinase 1	Homo sapiens (human)	Kd	5.1250	1	2
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	17.9750	2	4
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	17.9250	2	4
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	18.5500	2	4
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	5.3350	1	2
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	6.6000	1	2
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	3.2390	1	2
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	18.8000	2	4
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	18.9750	2	4
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	17.9500	2	4
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	20.0000	2	4
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	7.6500	1	2
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	10.0000	1	2
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	17.5375	2	4
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	18.4000	2	4
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	20.0980	2	5
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	17.5700	2	4
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	17.5198	2	4
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	30.0000	1	2
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	2
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	5.4800	1	2
Myosin light chain kinase 3	Homo sapiens (human)	Kd	20.0000	2	4
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	10.0000	1	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	19.4750	2	4
Myosin-10	Homo sapiens (human)	Kd	30.0000	1	3
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	2
Myosin-IIIa	Homo sapiens (human)	Kd	10.0000	1	2
Myosin-IIIb	Homo sapiens (human)	Kd	10.0000	1	2
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	2
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	20.0000	2	4
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	16.1000	3	6
NT-3 growth factor receptor	Homo sapiens (human)	Kd	5.4650	1	2
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	5.3100	1	2
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	13.6367	2	3
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	2
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	2
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	5.8500	1	2
Peroxisomal acyl-coenzyme A oxidase 1	Homo sapiens (human)	Kd	30.0000	1	2
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	2
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	5.1400	1	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	10	20
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	1	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	Homo sapiens (human)	Kd	30.0000	1	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	5.8000	1	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	18.3250	2	4
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	20.4800	2	5
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	5.9500	1	2
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	6.0000	1	2
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	17.9750	2	4
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	2
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	5.2350	1	2
Protein kinase C alpha type	Homo sapiens (human)	Kd	30.0000	1	2
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	1	2
Protein kinase C delta type	Homo sapiens (human)	Kd	22.0000	2	5
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	1	2
Protein kinase C eta type	Homo sapiens (human)	Kd	10.0000	1	2
Protein kinase C iota type	Homo sapiens (human)	Kd	20.0000	2	4
Protein kinase C theta type	Homo sapiens (human)	Kd	20.0000	2	4
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	17.7275	2	4
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	20.0000	2	4
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	10.2240	5	10
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	6.5000	1	2
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	20.0000	2	4
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	2
Pyridoxal kinase	Homo sapiens (human)	Kd	30.0000	1	2
Rab-like protein 3	Homo sapiens (human)	Kd	30.0000	1	2
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	2	4
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	2	4
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	20.0000	2	4
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	2
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	3
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	1	2
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	10.0000	1	2
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	1	2
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	10.0000	1	2
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	5.7500	1	2
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	20.0000	2	4
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	30.0000	1	2
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	10.0000	1	2
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	8.4928	8	16
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	20.0000	2	4
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	19.6750	2	4
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	5.5500	1	2
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	5.0305	1	2
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	18.5714	3	7
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	10.0000	2	4
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	19.9750	2	4
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	16.6667	3	6
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	15.1833	3	6
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	16.1333	3	6
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	18.5250	2	4
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	15.0620	1	2
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	2
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	2
Septin-9	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	17.5725	2	4
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	18.7000	2	4
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	7.0000	1	2
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	6.7500	1	2
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	18.4500	2	4
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	17.9750	2	4
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	5.4200	1	2
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase ATR	Homo sapiens (human)	Kd	30.0000	1	2
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	16.6667	3	6
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	5.7000	1	2
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	5.4950	1	2
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	7.2500	1	2
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	17.6000	2	4
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	22.0000	2	5
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	5.4450	1	2
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	18.4000	2	4
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase N3	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	17.6500	2	4
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	23.3333	2	6
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	9.3500	1	2
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	6.4500	1	2
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	5.5500	1	2
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	6.3000	1	2
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	10.0000	1	2
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	9.1500	1	2
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	17.6025	2	4
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	6.3000	1	2
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	16.6667	2	3
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	5.2350	1	2
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	2.7945	2	4
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	18.1250	2	4
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	18.1500	2	4
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	17.6150	2	4
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	17.8000	2	4
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	17.5108	2	4
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	17.7425	2	4
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	18.0000	2	4
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	5.7500	1	2
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	2
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	20.0000	2	4
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	1	2
Signal recognition particle receptor subunit alpha	Homo sapiens (human)	Kd	30.0000	1	2
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
SRSF protein kinase 1	Homo sapiens (human)	Kd	5.0205	1	2
SRSF protein kinase 2	Homo sapiens (human)	Kd	5.2500	1	2
SRSF protein kinase 3	Homo sapiens (human)	Kd	5.8000	1	2
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	17.5875	2	4
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	3
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	10.0000	1	2
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	2
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	3
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	6.0500	1	2
TGF-beta receptor type-1	Homo sapiens (human)	Kd	20.0000	2	4
TGF-beta receptor type-2	Homo sapiens (human)	Kd	20.0000	2	4
Thyroid hormone receptor-associated protein 3	Homo sapiens (human)	Kd	30.0000	1	2
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	17.5775	2	4
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	2
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	2
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	9.2741	16	32
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	19.2250	2	4
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	5.9500	1	2
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	13.9667	2	3
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	10.0000	1	2
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	15.4500	3	6
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	13.4767	2	3
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	5.2350	1	2
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	17.5800	2	4
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	17.8250	2	4
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	5.6000	1	2
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	6.0000	1	2
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	5.0550	1	2
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	10.0000	1	2
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	20.0000	2	4
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	10.0000	1	2
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	17.8500	2	4
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	1	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	2
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	1	2
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	2
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	30.0000	1	3
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	10.0000	1	2
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	10.0000	1	2
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	EC50	2.5000	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	10.0000	1	2
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	5.7000	1	2
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	2
Wee1-like protein kinase	Homo sapiens (human)	Kd	20.0000	2	4
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	1	2

chemdatabank.com

c-Met tyrosine kinase inhibitor

Members (3)

Research

Studies (33)

Study Types

Protein Targets (499)

Potency Measurements

Inhibition Measurements

Activation Measurements