Roles > EC 3.6.5.2 (small monomeric GTPase) inhibitor
Page last updated: 2024-08-05 15:41:34
EC 3.6.5.2 (small monomeric GTPase) inhibitor
null
ChEBI ID: 144981
Members (2)
| Member | Definition | Class |
|---|
| nsc 23766 | An aminopyrimidine that is 6-methylpyrimidine-2,4-diamine in which the amino groups at positions 2 and 4 are substituted by 5-(diethylamino)pentan-2-yl and 4-amino-2-methylquinolin-6-yl groups respectively. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). | NSC 23766 |
| nsc 23766 | A hydrochloride resulting from the formal reaction of NSC 23766 with 3 mol eq. of hydrogen chloride. An inhibitor of the signalling G-protein known as RAC1 (Ras-related C3 botulinum toxin substrate 1). | NSC 23766 trihydrochloride |
Research
Studies (209)
| Timeframe | Studies, Drugs with This Role(%) | All Drugs % |
|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 47 (22.49) | 29.6817 |
| 2010's | 134 (64.11) | 24.3611 |
| 2020's | 28 (13.40) | 2.80 |
Study Types
| Publication Type | Studies, Drugs with this Role (%) | All Drugs (%) |
|---|
| Trials | 0 (0.00%) | 5.53% |
| Reviews | 3 (1.42%) | 6.00% |
| Case Studies | 0 (0.00%) | 4.05% |
| Observational | 0 (0.00%) | 0.25% |
| Other | 209 (98.58%) | 84.16% |
Protein Targets (8)
Potency Measurements
Inhibition Measurements
Other Measurements