Page last updated: 2024-08-05 12:19:57
chloroindole
A compound based on an indole skeleton, containing one or more chlorine atoms
ChEBI ID: 52508
Members (3)
Member | Definition | Role |
---|---|---|
5-bromo-4-chloroindoxyl acetate | An acetate ester obtained by formal condensation of the carboxy group of acetic acid with the hydroxy group of 5-bromo-4-chloroindoxyl. | 5-bromo-4-chloro-3-indolyl acetate |
n-(3-chloro-7-indolyl)-1,4-benzenedisulphonamide | A chloroindole that is 3-chloro-1H-indole substituted by a [(4-sulfamoylphenyl)sulfonyl]nitrilo group at position 7. It is a carbonic anhydrase inhibitor and a potential anti-cancer agent currently in clinical development. | indisulam |
scio-469 | An indolecarboxamide obtained by formal condensation of the carboxy group of 6-chloro-3-[(dimethylamino)(oxo)acetyl]-1-methylindole-5-carboxylic acid with the secondary amino group of (2S,5R)-1-[(4-fluorophenyl)methyl]-2,5-dimethylpiperazine. It is a potent inhibitor of MAPK and exhibits anti-cancer properties. | talmapimod |
Research
Studies (193)
Timeframe | Studies, Drugs in This Class (%) | All Drugs % |
---|---|---|
pre-1990 | 10 (5.18) | 18.7374 |
1990's | 1 (0.52) | 18.2507 |
2000's | 93 (48.19) | 29.6817 |
2010's | 64 (33.16) | 24.3611 |
2020's | 25 (12.95) | 2.80 |
Study Types
Publication Type | Studies, Drugs in This Class (%) | All Drugs (%) |
---|---|---|
Trials | 17 (8.72%) | 5.53% |
Reviews | 11 (5.64%) | 6.00% |
Case Studies | 2 (1.03%) | 4.05% |
Observational | 0 (0.00%) | 0.25% |
Other | 165 (84.62%) | 84.16% |