A malignant tumor arising from the embryonic remains of the notochord. It is also called chordocarcinoma, chordoepithelioma, and notochordoma. (Dorland, 27th ed)
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| "Chondroid chordomas are cartilage-rich neoplasms, most often located in the spheno-occipital region, that have a better prognosis than classic chordomas." | ( Bromley, CM; Landas, SK; Sturm, MT; Walker, WP, 1991) |
| "Chordomas are rare slow-growing but locally invasive tumors." | ( Kunze, KD; Lossnitzer, A; Zotter, S, 1986) |
| "Chondroid chordomas are shown to possess cytokeratins and to stain with HMFG-2 as do ordinary chordomas." | ( Salisbury, JR, 1987) |
| "Chordomas are a low grade, tenacious, but eventually lethal neoplasm for which little improvement in outcome has been reported." | ( Martin, AE; McKeown, J; Spratt, JS, 1981) |
| ""Chondroid chordoma" is a controversial and confusing entity that was originally described by Heffelfinger and colleagues as a biphasic malignant neoplasm possessing elements of both chordoma and cartilaginous tissue." | ( Biava, CG; Davis, RL; Jeffrey, PB, 1995) |
| "Chordomas are rare neoplasms that show a proclivity for the spheno-occiput and sacral regions." | ( Forsyth, PJ; McGivney, DJ; Mitchell, A; Scheithauer, BW; Unni, KK; Wold, LE, 1993) |
| "Chordoma is a neoplasm arising from the primitive notochord." | ( Ghosh, BC; Jones, B; Skelton, HG, 1994) |
| "Two intracranial chordomas are presented: a typical chordoma and a chondroid tumour." | ( Aesch, B; Cotty, P; de Toffol, B; Leproux, F, 1993) |
| "Chordoma is a well-known bone tumor that shows epithelioid features and in which the expression of cytokeratins (CKs) has been reported to appear very frequently." | ( Chuman, H; Fukui, M; Iwamoto, Y; Naka, T; Shinohara, N; Tsuneyoshi, M, 1997) |
| "Parachordomas are rare cutaneous tumors that show virtually identical histologic findings to chordomas." | ( Argenyi, ZB; Henghold, WB; Imlay, SP; McCollough, ML; Stone, MS, 1998) |
| "Even though parachordoma is usually regarded as a benign soft tissue neoplasm, two recurrences occurred in our case." | ( Cho, KJ; Chung, JH; Koh, JS; Lee, SY, 2000) |
| "Chordoma is the fourth most common malignant primary neoplasm of the skeleton and almost the only one showing a real epithelial phenotype." | ( Aigner, T; Fehn, M; Gottschalk, D; Kirchner, T; Patt, S; Saeger, W, 2001) |
| "Chordoma is a rare and slow-growing malignant neoplasm that arises from the embryonic notochord." | ( Chen, CC; Chiu, PC; Ho, JT; Huang, SM; Lai, PH; Tseng, HH, 2003) |
| "Parachordoma is a rare soft tissue tumor that morphologically resembles chordoma of the axial skeleton but occurs in a peripheral site." | ( Barr, EM; Bonar, SF; Li, LX; McCarthy, SW; Palmer, AA; Schatz, J; Scolyer, RA; Soper, J; Stalley, P; Wills, EJ, 2004) |
| "Chordomas are rare neoplasms originating along the neuraxis." | ( Bruno, E; Di Girolamo, S; Floris, R; Napolitano, B; Ottaviani, F; Schillaci, O, 2005) |
| "Chordomas are malignant tumours that occur along the spine and are thought to derive from notochordal remnants." | ( Boshoff, C; Flanagan, AM; Henderson, S; Jacques, TS; Odell, E; Presneau, N; Tirabosco, R; Vujovic, S, 2006) |
| "Chordomas are rare tumors of the skull base and the spine." | ( Debus, J; Hof, H; Welzel, T, 2006) |
| "Chordomas are rare neoplasms arising along the axial skeleton." | ( Boari, N; Doglioni, C; Longoni, M; Mortini, P; Orzan, F; Riva, P; Terreni, MR, 2007) |
| "Chordoma is an uncommon primary bone tumor and the thoracic spine is the least common of all sites for a chordoma." | ( Ishigame, K; Kato, S; Miyazawa, N; Satoh, Y; Shinohara, T, 2008) |
| "Chordoma is a rare malignant bone tumor derived from notochordal rests, and the most common site is the sacrococcygeal region." | ( Kim, HS; Park, SA, 2008) |
| "Chordomas are rare, malignant bone neoplasms in which the pathogenic mechanisms remain unknown." | ( Han, S; Hornicek, FJ; Nielsen, GP; Polizzano, C; Ramesh, V; Rosenberg, AE, 2009) |
| "Chordomas are rare malignant bone tumors that arise at both the cranial and the caudal ends of the axial skeleton, characteristically destroying the bone." | ( Jiang, L; Liu, C; Liu, X; Liu, Z; Ma, Q; Wei, F; Zhou, H, 2009) |
| "Chordomas are rare tumors of the axial skeleton for which surgical resection remains the most reliable means of cure." | ( Antonescu, C; Boland, P; Choy, E; Delaney, T; Duan, Z; Harmon, D; Healey, J; Hornicek, F; Iafrate, J; Mankin, H; Nielsen, P; Raskin, K; Rosenberg, A; Schwab, J; Springfield, D; Yang, C; Yoon, S, 2009) |
| "Intradural chordomas are very rare." | ( Bhat, DI; Rojin, A; Sampath, S; Shankar, SK; Yasha, M, 2010) |
| "Chordomas are rare primary bone tumors for which surgery is classically the first-line treatment." | ( Chauffert, B; Feutray, S; Guiu, B; Guiu, S, 2009) |
| "Chordomas are rare tumors arising from the axial skeleton." | ( Kotasek, D; Parnis, FX; Singhal, N, 2009) |
| "Clival chordomas are frequently midline structures." | ( Aydin, Y; Colak, I; Musluman, AM; Soglu, HC; Ugurlu, K; Yilmaz, A, 2011) |
| "Chordomas are relatively rare tumors that arise from the neuraxis." | ( Baimeedi, P; Bergman, T; Grossbach, A; McDonald, W, 2011) |
| "Chordoma is a rare type of malignant bone tumor and is known to arise from the remnants of the notochord." | ( Acar, H; Aydemir, E; Bayrak, OF; Gulluoglu, S; Ozen, M; Sahin, F; Sevli, S; Yalvac, ME, 2011) |
| "Chordomas are rare bone tumors of notochord remnants that may occur anywhere within the axial skeleton." | ( Al-Rahawan, MM; Mitchell, CS; Siebert, JD; Smith, SD, 2012) |
| "Chordomas are very rare low-grade malignant bone tumors that arise from the embryonic rests of the notochord." | ( Bertucci, F; Chetaille, B; Guiramand, J; Launay, SG; Medina, F; Moureau-Zabotto, L; Nazarian, S; Perrot, D, 2011) |
| "Chordomas are midline tumors that arise from embryonic remnants of the notochord and are considered to be malignant tumors because of their tendency to invade and destroy the involved bone." | ( Alafaci, C; Barresi, V; Caffo, M; Granata, F; Tuccari, G, 2012) |
| "Skull base chordomas are challenging tumors due to their deep surgical location and resistance to conventional radiotherapy." | ( Bianchi, F; Cenci, T; D'Alessandris, QG; De Maria, R; Larocca, LM; Maira, G; Martini, M; Pallini, R; Ricci-Vitiani, L; Runci, D; Stancato, L, 2013) |
| "Spinal chordomas are more often located on the midline and are associated with marked destruction of the vertebral bodies." | ( Caranci, F; Del Basso De Caro, ML; Elefante, A; Guadagno, E; Maiuri, F; Mariniello, G; Peca, C; Severino, R, 2013) |
| "Chordomas are rare malignancies of the axial skeleton." | ( Beham, A; Froehlich, EV; Haybaeck, J; Lazáry, A; Leithner, A; Liegl, B; Lohberger, B; Pal Varga, P; Quehenberger, F; Rinner, B; Scheipl, S, 2013) |
| "Chordomas are rare primary bone tumors that occur along the neuraxis." | ( Bettegowda, C; Burger, PC; Connis, N; Gallia, GL; Hann, CL; Jiao, Y; Ruzevick, J; Siu, IM; Xia, X; Zhao, Q, 2013) |
| "Chordoma is a malignant tumor thought to arise from remnants of the embryonic notochord, with its origin in the bones of the axial skeleton." | ( Burger, A; Drummond, IA; Haber, DA; Nielsen, GP; Peterson, RT; Selig, MK; Tomar, R; Vasilyev, A, 2014) |
| "Chordomas are rare and indolent bone tumors that arise in the skull base and mobile spine." | ( Bozzi, F; Conca, E; Dagrada, G; Gronchi, A; Manenti, G; Messina, A; Panizza, P; Pierotti, MA; Pilotti, S; Stacchiotti, S; Tamborini, E, 2014) |
| "Chordomas are relatively rare lesions of the bones." | ( Debus, J; Edler, L; Habl, G; Herfarth, K; Jäckel, O; Jensen, AD; Oelmann, J; Röder, F; Uhl, M, 2014) |
| "Chordomas are rare, low grade, malignant tumours derived from the ectopic remnants of the notochord that line the axial skeleton." | ( Emori, M; Kaya, M; Sasaki, M; Soma, T; Sugita, S; Yamashita, T, 2014) |
| "Chordomas are an aggressive rare type of malignant bone tumors arising from the remnant of the notochord." | ( Alholle, A; Bauer, J; Brini, AT; Gentle, D; Gharanei, S; Grimer, R; Jeys, L; Latif, F; Maher, ER; Niada, S; Slater, A; Sumathi, VP, 2015) |
| "Chordoma is a rare, slow-growing primary malignant neoplasm of the axial skeleton, which arises from the remnants of the notochord." | ( Dai, Y; Kuang, L; Li, L; Li, Y; Lv, G; Wang, B, 2015) |
| "Chordomas are tumors that arise at vertebral bodies and the base of the skull." | ( Barth, H; Barth, TF; Böhm, M; Brüderlein, S; Flanagan, AM; Goerttler, LT; Kornmann, M; Lechel, A; Marienfeld, R; Mayer-Steinacker, R; Mellert, K; Möller, P; Schultheiss, M; von Baer, A; von Witzleben, A, 2015) |
| "Chordoma is a rare primary bone tumor derived from transformed notochord remnants." | ( Balsalobre, L; Beer-Furlan, A; Mangussi-Gomes, J; Stamm, AC; Vellutini, EA, 2016) |
| "Chordomas are rare malignant tumors that develop from embryonic remnants of the notochord and arise only in the midline from the clivus to the sacrum." | ( Gellner, V; Heitzer, E; Koele, W; Leithner, A; Liegl-Atzwanger, B; Lohberger, B; Meditz, K; Mokry, M; Rinner, B; Tomazic, PV, 2016) |
| "Chordoma is a rare malignant bone tumour with a poor prognosis and limited therapeutic options." | ( Amary, F; Barnard, M; Brüderlein, S; Cottone, L; Drewry, DH; Flanagan, AM; Guppy, N; Jorgensen, M; Leite, AP; Leithner, A; Möller, P; Pillay, N; Scheipl, S; Smith, JA; Strauss, SJ; Tirabosco, R; Turlais, F; Ye, H; Zuercher, WJ, 2016) |
| "Chordoma is a rare primary bone malignancy of notochord origin, representing 1-4% of malignant bone tumors." | ( Gleghorn, K; Goodwin, B; Sanchez, R, 2017) |
| "Chordoma is a rare slow-growing neoplasm of neuroectodermal origin, which frequently recurs after removal and has the potential to metastasize." | ( Derlin, T; Hueper, K; Sohns, JM, 2017) |
| "Chordomas are low-grade malignant tumors that are locally aggressive and have the potential to metastasize." | ( Bitzer, A; McCarthy, EF; Morris, CD, 2017) |
| "Chordomas are very rare tumors of the skull base and the sacrum." | ( Cornelius, JF; Ebbert, L; Eismann, L; Kamp, MA; Petridis, AK; Senger, B; Sorg, RV; Steiger, HJ, 2017) |
| "Extra-axial chordoma is a chordoma that occurs in non-axial locations." | ( Donati, DM; Errani, C; Righi, A; Tsukamoto, S; Vanel, D, 2018) |
| "Chordomas are rare bone tumors and treatment is commonly based on a combination of surgery and radiotherapy." | ( Choy, E; Duan, Z; Hornicek, FJ; Liu, T; Mankin, HJ; Shen, JK; Zhang, Y, 2018) |
| "BNCT and chordomas are characterized by the following immunohistological profile: vimentin+, cytokeratin+/-, epithelial membrane antigen (EMA)+/-, S100 protein+/-, brachyury+." | ( Barth, TFE; Möller, P; Scheil-Bertram, S; von Witzleben, A, 2018) |
| "Chordomas are rare bone tumors with no approved therapy." | ( Amboldi, N; Ballinari, D; Bosotti, R; Bozzi, F; Cozzi, L; Galvani, A; Gasparri, F; Isacchi, A; Magnaghi, P; Montagnoli, A; Orrenius, C; Pilotti, S; Raddrizzani, L; Salom, B; Somaschini, A; Sommer, J; Stacchiotti, S; Tamborini, E, 2018) |
| "Chordoma is a rare tumor of the bone derived from remnants of the notochord with pronounced chemoresistance." | ( Fuchs, R; Groselj-Strele, A; Heitzer, E; Kolb-Lenz, D; Leithner, A; Liegl-Atzwanger, B; Lohberger, B; Meditz, K; Pernitsch, D; Pritz, E; Rinner, B, 2018) |
| "Chordoma is a rare midline malignant tumor arising from embryonic remnants of the primitive notochord." | ( Chew, LL; Desai, V; Nor, FEM, 2018) |
| "Chordomas are malignant tumors arising from remnant notochordal tissue." | ( Barysauskas, CM; Bernstein, K; Chen, YE; Choy, E; Cote, GM; DeLaney, TF; Haynes, AB; Hornicek, F; Lozano-Calderon, S; Mullen, JT; Raskin, K; Schwab, J, 2018) |
| "Chordoma is a rare malignant tumor of the skull base and axial skeleton, with an incidence of less than 0." | ( Akgül Babacan, N; Akin Telli, T; Alan, O; Basoglu Tuylu, T; Dane, F; Ercelep, O; Hasanov, R; Kaya, S; Mutis, A; Tanrikulu Simsek, E; Yumuk, PF, 2018) |
| "Chordoma is a rare, slow-growing tumor thought to arise from remnants of embryonic notochord associated with an aggressive outcome." | ( Bayrak, OF; Çoban, EA; Gulluoglu, S; Kuskucu, A; Ozbey, U; Sahin, F; Türe, U; Tuysuz, EC; Yaltirik, CK, 2019) |
| "Chordomas are rare bone tumors with few therapeutic options." | ( Bauer, S; Bonekamp, D; Brandts, C; Brors, B; Chudasama, P; Eils, R; Fröhlich, M; Fröhling, S; Gieldon, L; Glimm, H; Gröschel, S; Groth, M; Heilig, CE; Heining, C; Horak, P; Hübschmann, D; Hutter, B; Kleinheinz, K; Klink, B; Krämer, S; Marschal, O; Mika, J; Penzel, R; Pfütze, K; Raimondi, F; Reisinger, E; Richter, D; Richter, S; Russell, RB; Schlenk, RF; Schlesner, M; Scholl, C; Schröck, E; Stenzinger, A; Uhrig, S; von Kalle, C; Warsow, G; Weichert, W; Wolf, S, 2019) |
| "Skull base chordomas are rare tumors arising from notochord." | ( Broggi, M; Bruzzone, MG; Calatozzolo, C; Campisi, G; Dei Cas, M; Ferroli, P; Ghidoni, R; La Corte, E; Paroni, R; Patanè, M; Pipolo, C; Pollo, B; Raggi, A; Schiavolin, S, 2019) |
| "BACKGROUND Chordoma is a rare, but aggressive bone tumor, primarily affecting the axial skeleton." | ( Bindal, P; Noor, A; Ramirez, M; Vredenburgh, J, 2020) |
| "Chordomas are rare and serious tumors with few effective treatments outside of aggressive surgery and radiation." | ( Brenner, JC; Heft Neal, ME; Jiang, H; Leonard, E; Mann, JE; McHugh, JB; Michmerhuizen, NL; Owen, JH; Prince, MEP; Wang, J; Zhai, J, 2020) |
| "Chordomas are uncommon, bone, axial, or (rarely) extra-axial tumors that are malignant and frequently recur but less commonly metastasize." | ( Barral, FG; Boutonnat, J; Dal Col, P; Dridi, M; Dumollard, JM; Karpathiou, G; Peoc'h, M, 2020) |
| "Chordoma are uncommon aggressive tumors of the skeleton." | ( Cornelius, JF; Gull, HH; Hänggi, D; Karadag, C; Mellert, K; Möller, P; Senger, B; Sorg, RV; Steiger, HJ, 2021) |
| "Chordomas are primary bone tumors that arise in the cranial base, mobile spine, and sacrococcygeal region, affecting patients of all ages." | ( Burger, PC; Connis, N; Cottone, L; Flanagan, AM; Gallia, GL; Hann, CL; Ji, C; Ruzevick, J; Siu, IM; Williamson, T; Xia, M; Zhang, H; Zhao, T, 2021) |
| "Chordomas are rare slow growing, malignant bone tumors of the axial skeleton with no approved medical treatment." | ( de Jong, D; Heitzer, E; Liegl-Atzwanger, B; Lohberger, B; Quehenberger, F; Rinner, B; Scheipl, S; Szuhai, K, 2021) |
| "Chordoma is a rare, locally invasive neoplasm of the axial skeleton." | ( Aoki, S; Ikawa, H; Imai, R; Koto, M; Shinoto, M; Takiyama, H; Tokuhiko, O; Tsuji, H; Yamada, S, 2022) |
| "Chordoma is a rare malignant tumor demonstrating notochordal differentiation." | ( Benita, Y; Cheah, JH; Frosch, MP; Gunnlaugsson, HO; Halvorsen, SC; Hoppe, B; Hopton, M; Hornicek, FJ; Korgaonkar, P; Nielsen, GP; Rosenberg, AE; Sassi, S; Schwab, JH; Trepanowski, N; Vanderburg, CR, 2023) |
| "Chordomas are rare slow growing tumors, arising from embryonic remnants of notochord with a close predilection for the axial skeleton." | ( Ashili, S; Bouffet, E; Carrillo, J; Freed, DM; Gill, JM; Juarez, T; Kesari, S; Levy, J; Nguyen, M; Patro, CPK; Sommer, J; Takasumi, Y; Truong, J; Wang, F; Xiu, J, 2023) |
| "Chordoma is an extremely rare, locally aggressive malignant bone tumor originating from undifferentiated embryonic remnants." | ( Chen, C; Guo, L; Guo, W; Huang, Y; Lan, J; Lou, J; Niu, J; Ren, T; Shi, Q; Tang, X; Wang, B; Wang, W; Xu, J; Yu, Y; Zhu, Y, 2023) |
| "Chordomas are rare, locally aggressive tumors that often occur in the axial spine, especially in the sacrum." | ( Korwutthikulrangsri, E; Ongard, S; Pisutbenya, J; Ruangchainikom, M; Sutipornpalangkul, W, 2023) |
| "Chordomas are slow-growing tumors derived from notochord remnants." | ( Abode-Iyamah, K; Akinduro, OO; Bon Nieves, A; Bydon, M; Clarke, MJ; Ghaith, AK; Kalani, M; Patel, N; Perez-Vega, C; Rose, P, 2023) |