Page last updated: 2024-08-05 15:47:21

EC 2.7.12.2 (mitogen-activated protein kinase kinase) inhibitor

An EC 2.7.12.* [dual-specificity kinases (those acting on Ser/Thr and Tyr residues)] inhibitor that inhibits the action of mitogen-activated protein kinase kinase (EC 2.7.12.2).

ChEBI ID: 88286

Members (3)

MemberDefinitionClass
GDC-0623A member of the class of imidazopyridines that is imidazo[1,5-a]pyridine substituted by (2-fluoro-4-iodophenyl)amino and (2-hydroxyethoxy)aminoacyl groups at positions 5 and 6. It is a potent ATP non-competitive inhibitor of MEK1 (Ki = 0.13nM) and also has efficacy against both mutant BRAF and mutant KRAS. It is in clinical development for treatment of patients with locally advanced or metastatic solid tumors.GDC-0623
pd 0325901A hydroxamic acid ester that is benzhydroxamic acid (N-hydroxybenzamide) in which the hydroxamic acid group has been converted to the corresponding 2,3-dihydroxypropyl ester and in which the benzene ring has been substituted at position 2 by a (2-fluoro-4-iodophenyl)amino group and at positions 3 and 4 by fluorines (the R enantiomer).PD 0325901
SL-327A nitrile that is acrylonitrile in which the hydrogen attached to the same carbon as the cyano group has been replaced by an o-(trifluoromethyl)phenyl group, while the remaining hydrogens of the ethenyl group have been replaced by amino and (4-aminophenyl)sulfanyl groups. The configuration of the double bond is not specified. It is an inhibitor of MEK1 and MEK2.SL-327

Research

Studies (302)

TimeframeStudies, Drugs with This Role(%)All Drugs %
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's24 (7.95)29.6817
2010's242 (80.13)24.3611
2020's36 (11.92)2.80

Study Types

Publication TypeStudies, Drugs with this Role (%)All Drugs (%)
Trials7 (2.24%)5.53%
Reviews4 (1.28%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other301 (96.47%)84.16%

Protein Targets (312)

Potency Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
AR proteinHomo sapiens (human)Potency13.013822
aryl hydrocarbon receptorHomo sapiens (human)Potency5.308011
cytochrome P450 2C9, partialHomo sapiens (human)Potency16.933011
cytochrome P450 2D6Homo sapiens (human)Potency18.999111
cytochrome P450 family 3 subfamily A polypeptide 4Homo sapiens (human)Potency37.908311
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_aHomo sapiens (human)Potency0.004211
estrogen nuclear receptor alphaHomo sapiens (human)Potency7.178223
EWS/FLI fusion proteinHomo sapiens (human)Potency19.508248
GVesicular stomatitis virusPotency16.933011
HLA class I histocompatibility antigen, B alpha chain Homo sapiens (human)Potency16.933011
Inositol hexakisphosphate kinase 1Homo sapiens (human)Potency16.933012
Interferon betaHomo sapiens (human)Potency16.933011

Inhibition Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
Cytochrome P450 1A2Homo sapiens (human)IC505.007522
Cytochrome P450 2C19Homo sapiens (human)IC5010.000011
Cytochrome P450 2C9 Homo sapiens (human)IC5010.000011
Cytochrome P450 2D6Homo sapiens (human)IC505.007522
Cytochrome P450 3A4Homo sapiens (human)IC5010.000022
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)IC500.028588
Dual specificity mitogen-activated protein kinase kinase 1Mus musculus (house mouse)IC500.000311
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)IC500.078033
Mitogen-activated protein kinase 1Homo sapiens (human)IC5015.006244
Mitogen-activated protein kinase kinase kinase 8Homo sapiens (human)IC5025.000011
Potassium voltage-gated channel subfamily H member 2Homo sapiens (human)IC504.400011
Serine/threonine-protein kinase B-rafHomo sapiens (human)IC500.006011

Activation Measurements

ProteinTaxonomyMeasurementAverage (mM)Bioassay(s)Drugs
26S proteasome regulatory subunit 6BHomo sapiens (human)Kd30.000011
5'-AMP-activated protein kinase catalytic subunit alpha-1Homo sapiens (human)Kd30.000011
5'-AMP-activated protein kinase subunit gamma-1Homo sapiens (human)Kd30.000012
5'-AMP-activated protein kinase subunit gamma-2Homo sapiens (human)Kd30.000011
AarF domain-containing protein kinase 1Homo sapiens (human)Kd30.000011
Actin-related protein 2Homo sapiens (human)Kd30.000011
Actin-related protein 3Homo sapiens (human)Kd30.000011
Activated CDC42 kinase 1Homo sapiens (human)Kd30.000011
Activin receptor type-1Homo sapiens (human)Kd30.000011
Activin receptor type-1BHomo sapiens (human)Kd30.000011
Activin receptor type-2BHomo sapiens (human)Kd30.000011
Acyl-CoA dehydrogenase family member 10Homo sapiens (human)Kd30.000011
Acyl-CoA dehydrogenase family member 11Homo sapiens (human)Kd30.000011
Adenine phosphoribosyltransferaseHomo sapiens (human)Kd30.000011
Adenosine kinaseHomo sapiens (human)Kd30.000011
Adenylate kinase 2, mitochondrialHomo sapiens (human)Kd30.000011
ADP/ATP translocase 2Homo sapiens (human)Kd30.000011
ADP/ATP translocase 3Homo sapiens (human)Kd30.000011
AP2-associated protein kinase 1Homo sapiens (human)Kd30.000011
ATP-dependent 6-phosphofructokinase, platelet typeHomo sapiens (human)Kd30.000012
ATP-dependent RNA helicase DDX1Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX3XHomo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DDX42Homo sapiens (human)Kd30.000011
ATP-dependent RNA helicase DHX30Homo sapiens (human)Kd30.000011
Atypical kinase COQ8A, mitochondrialHomo sapiens (human)Kd30.000011
Aurora kinase AHomo sapiens (human)Kd30.000011
Aurora kinase BHomo sapiens (human)Kd30.000011
Beta-adrenergic receptor kinase 1Homo sapiens (human)Kd30.000011
BMP-2-inducible protein kinaseHomo sapiens (human)Kd30.000011
Bone morphogenetic protein receptor type-1AHomo sapiens (human)Kd30.000011
Bone morphogenetic protein receptor type-1BHomo sapiens (human)Kd30.000011
Bone morphogenetic protein receptor type-2Homo sapiens (human)Kd30.000011
Breakpoint cluster region proteinHomo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase kinase 2Homo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase type II subunit deltaHomo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase type II subunit gammaHomo sapiens (human)Kd30.000011
Calcium/calmodulin-dependent protein kinase type IVHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit alphaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit betaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase catalytic subunit gammaHomo sapiens (human)Kd30.000011
cAMP-dependent protein kinase type II-alpha regulatory subunitHomo sapiens (human)Kd30.000011
Casein kinase I isoform alphaHomo sapiens (human)Kd30.000011
Casein kinase I isoform deltaHomo sapiens (human)Kd30.000011
Casein kinase I isoform epsilonHomo sapiens (human)Kd30.000011
Casein kinase I isoform gamma-1Homo sapiens (human)Kd30.000011
Casein kinase I isoform gamma-2Homo sapiens (human)Kd30.000011
Casein kinase I isoform gamma-3Homo sapiens (human)Kd30.000011
Casein kinase II subunit alpha'Homo sapiens (human)Kd30.000011
cGMP-dependent protein kinase 1 Homo sapiens (human)Kd30.000011
Choline-phosphate cytidylyltransferase AHomo sapiens (human)Kd30.000011
Chromodomain-helicase-DNA-binding protein 4Homo sapiens (human)Kd30.000011
Citron Rho-interacting kinaseHomo sapiens (human)Kd30.000011
Cyclin-dependent kinase 1Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 12Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 13Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 16Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 17Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 2Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 3Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 4Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 6Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 7Homo sapiens (human)Kd30.000011
Cyclin-dependent kinase 9Homo sapiens (human)Kd30.000011
Cyclin-dependent-like kinase 5 Homo sapiens (human)Kd30.000011
Cyclin-G-associated kinaseHomo sapiens (human)Kd30.000011
Cysteine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Cytochrome c1, heme protein, mitochondrialHomo sapiens (human)Kd30.000011
dCTP pyrophosphatase 1Homo sapiens (human)Kd30.000011
Delta(24)-sterol reductaseHomo sapiens (human)Kd30.000011
Deoxycytidine kinaseHomo sapiens (human)Kd30.000011
Discoidin domain-containing receptor 2Homo sapiens (human)Kd30.000011
DNA replication licensing factor MCM4Homo sapiens (human)Kd30.000011
DNA topoisomerase 2-alphaHomo sapiens (human)Kd30.000011
DNA topoisomerase 2-betaHomo sapiens (human)Kd30.000011
DnaJ homolog subfamily A member 1Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 1Homo sapiens (human)Kd0.021844
Dual specificity mitogen-activated protein kinase kinase 2Homo sapiens (human)Kd0.056022
Dual specificity mitogen-activated protein kinase kinase 3Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 4Homo sapiens (human)Kd30.000011
Dual specificity mitogen-activated protein kinase kinase 5Homo sapiens (human)Kd0.808011
Dual specificity mitogen-activated protein kinase kinase 6Homo sapiens (human)Kd30.000012
Dual specificity protein kinase CLK1Homo sapiens (human)Kd30.000011
Dual specificity protein kinase CLK2Homo sapiens (human)Kd30.000011
Dual specificity protein kinase CLK3Homo sapiens (human)Kd30.000011
Dual specificity protein kinase CLK4Homo sapiens (human)Kd30.000011
Dual specificity protein kinase TTKHomo sapiens (human)Kd30.000011
Dual specificity testis-specific protein kinase 1Homo sapiens (human)Kd30.000011
Dual specificity tyrosine-phosphorylation-regulated kinase 1AHomo sapiens (human)Kd30.000011
Dynamin-like 120 kDa protein, mitochondrialHomo sapiens (human)Kd30.000011
EKC/KEOPS complex subunit TP53RKHomo sapiens (human)Kd30.000011
Electron transfer flavoprotein subunit betaHomo sapiens (human)Kd30.000011
Elongation factor Tu, mitochondrialHomo sapiens (human)Kd30.000011
Ephrin type-A receptor 1Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 2Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 4Homo sapiens (human)Kd30.000011
Ephrin type-A receptor 5Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 2Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 3Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 4Homo sapiens (human)Kd30.000011
Ephrin type-B receptor 6Homo sapiens (human)Kd30.000011
Epidermal growth factor receptorHomo sapiens (human)Kd30.000011
Epithelial discoidin domain-containing receptor 1Homo sapiens (human)Kd30.000011
Eukaryotic translation initiation factor 2-alpha kinase 1Homo sapiens (human)Kd30.000011
Eukaryotic translation initiation factor 5BHomo sapiens (human)Kd30.000011
Exosome RNA helicase MTR4Homo sapiens (human)Kd30.000011
Ferrochelatase, mitochondrialHomo sapiens (human)Kd30.000011
Fibroblast growth factor receptor 1Homo sapiens (human)Kd30.000011
Focal adhesion kinase 1Homo sapiens (human)Kd30.000011
G protein-coupled receptor kinase 6Homo sapiens (human)Kd30.000011
General transcription and DNA repair factor IIH helicase subunit XPDHomo sapiens (human)Kd30.000011
Glycine--tRNA ligaseHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, brain formHomo sapiens (human)Kd30.000011
Glycogen phosphorylase, liver formHomo sapiens (human)Kd30.000011
Glycogen synthase kinase-3 alphaHomo sapiens (human)Kd30.000011
Glycogen synthase kinase-3 betaHomo sapiens (human)Kd30.000012
GTP-binding nuclear protein RanHomo sapiens (human)Kd30.000012
Heme oxygenase 2Homo sapiens (human)Kd30.000011
Hepatocyte growth factor receptorHomo sapiens (human)Kd30.000011
High affinity nerve growth factor receptorHomo sapiens (human)Kd30.000011
Inhibitor of nuclear factor kappa-B kinase subunit epsilonHomo sapiens (human)Kd30.000011
Inosine-5'-monophosphate dehydrogenase 2Homo sapiens (human)Kd30.000011
Insulin receptorHomo sapiens (human)Kd30.000011
Insulin-like growth factor 1 receptorHomo sapiens (human)Kd30.000011
Integrin-linked protein kinaseHomo sapiens (human)Kd30.000011
Interleukin-1 receptor-associated kinase 1Homo sapiens (human)Kd30.000011
Interleukin-1 receptor-associated kinase 3Homo sapiens (human)Kd30.000011
Interleukin-1 receptor-associated kinase 4Homo sapiens (human)Kd30.000011
LIM domain kinase 1Homo sapiens (human)Kd30.000011
LIM domain kinase 2Homo sapiens (human)Kd30.000011
Macrophage-stimulating protein receptorHomo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 2Homo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 3Homo sapiens (human)Kd30.000011
MAP kinase-activated protein kinase 5Homo sapiens (human)Kd30.000011
MAP/microtubule affinity-regulating kinase 3Homo sapiens (human)Kd30.000011
MAP/microtubule affinity-regulating kinase 4Homo sapiens (human)Kd30.000011
Maternal embryonic leucine zipper kinaseHomo sapiens (human)Kd30.000011
Membrane-associated progesterone receptor component 1Homo sapiens (human)Kd30.000011
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinaseHomo sapiens (human)Kd30.000011
Misshapen-like kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 10Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 11Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 14Homo sapiens (human)Kd30.000012
Mitogen-activated protein kinase 15Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 3 Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 7Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase 8Homo sapiens (human)Kd30.000012
Mitogen-activated protein kinase 9Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 11Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 2Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 20Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 3Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 4Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 5Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase 6Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 1Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 2Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 3Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 4Homo sapiens (human)Kd30.000011
Mitogen-activated protein kinase kinase kinase kinase 5Homo sapiens (human)Kd30.000011
Mitotic checkpoint serine/threonine-protein kinase BUB1Homo sapiens (human)Kd30.000011
Multifunctional protein ADE2Homo sapiens (human)Kd30.000011
Myosin light chain kinase 3Homo sapiens (human)Kd30.000011
Myosin light chain kinase, smooth muscleHomo sapiens (human)Kd30.000011
Myosin-10Homo sapiens (human)Kd30.000011
Myosin-14Homo sapiens (human)Kd30.000011
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13Homo sapiens (human)Kd30.000011
Non-receptor tyrosine-protein kinase TNK1Homo sapiens (human)Kd30.000011
Non-receptor tyrosine-protein kinase TYK2Homo sapiens (human)Kd30.000011
NUAK family SNF1-like kinase 2Homo sapiens (human)Kd30.000011
Nucleolar GTP-binding protein 1Homo sapiens (human)Kd30.000011
Obg-like ATPase 1Homo sapiens (human)Kd30.000011
PAS domain-containing serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 1Homo sapiens (human)Kd30.000011
Peroxisomal acyl-coenzyme A oxidase 3Homo sapiens (human)Kd30.000011
Phenylalanine--tRNA ligase beta subunitHomo sapiens (human)Kd30.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 alphaHomo sapiens (human)Kd30.000011
Phosphatidylinositol 5-phosphate 4-kinase type-2 gammaHomo sapiens (human)Kd30.000011
Phosphorylase b kinase gamma catalytic chain, liver/testis isoformHomo sapiens (human)Kd30.000011
Platelet-derived growth factor receptor betaHomo sapiens (human)Kd30.000012
Probable ATP-dependent RNA helicase DDX6Homo sapiens (human)Kd30.000011
Protein kinase C alpha typeHomo sapiens (human)Kd30.000011
Protein kinase C beta typeHomo sapiens (human)Kd30.000011
Protein kinase C delta typeHomo sapiens (human)Kd30.000011
Protein kinase C iota typeHomo sapiens (human)Kd30.000011
Protein kinase C theta typeHomo sapiens (human)Kd30.000011
Protein-tyrosine kinase 2-betaHomo sapiens (human)Kd30.000011
Protein-tyrosine kinase 6Homo sapiens (human)Kd30.000011
Proto-oncogene tyrosine-protein kinase receptor RetHomo sapiens (human)Kd30.000012
Proto-oncogene tyrosine-protein kinase SrcHomo sapiens (human)Kd30.000011
Putative heat shock protein HSP 90-beta 2Homo sapiens (human)Kd30.000011
Pyridoxal kinaseHomo sapiens (human)Kd30.000011
Rab-like protein 3Homo sapiens (human)Kd30.000011
RAC-alpha serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
RAC-beta serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
RAC-gamma serine/threonine-protein kinaseHomo sapiens (human)Kd30.000011
Ras-related protein Rab-10Homo sapiens (human)Kd30.000011
Ras-related protein Rab-27AHomo sapiens (human)Kd30.000011
Ras-related protein Rab-6AHomo sapiens (human)Kd30.000011
Receptor-interacting serine/threonine-protein kinase 2Homo sapiens (human)Kd30.000011
Receptor-interacting serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000011
Receptor-type tyrosine-protein kinase FLT3Homo sapiens (human)Kd30.000011
Rho-associated protein kinase 1Homo sapiens (human)Kd30.000011
Rho-associated protein kinase 2Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-1Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-3Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-4Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-5Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase alpha-6Homo sapiens (human)Kd30.000011
Ribosomal protein S6 kinase beta-1Homo sapiens (human)Kd30.000011
Ribosyldihydronicotinamide dehydrogenase [quinone]Homo sapiens (human)Kd30.000011
RNA cytidine acetyltransferaseHomo sapiens (human)Kd30.000011
Septin-9Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 10Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 16Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 24Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 26Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase 4Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase A-RafHomo sapiens (human)Kd30.000012
Serine/threonine-protein kinase B-rafHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Chk1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase D2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase D3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ICKHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase LATS1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MARK2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MRCK alphaHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MRCK betaHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase MRCK gammaHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase N1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase N2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase N3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek2Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase Nek3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek7Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase Nek9Homo sapiens (human)Kd30.000012
Serine/threonine-protein kinase NLKHomo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PAK 2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PAK 4Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PAK 6Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase pim-1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase pim-2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PLK1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase PLK4Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase receptor R3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase SIK2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase SIK3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase STK11Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase TAO1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase TAO2Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase TAO3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase TBK1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ULK1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase ULK3Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase/endoribonuclease IRE1Homo sapiens (human)Kd30.000011
Serine/threonine-protein kinase/endoribonuclease IRE2Homo sapiens (human)Kd30.000012
Signal recognition particle receptor subunit alphaHomo sapiens (human)Kd30.000011
STE20-like serine/threonine-protein kinase Homo sapiens (human)Kd30.000011
STE20-related kinase adapter protein alphaHomo sapiens (human)Kd30.000011
Structural maintenance of chromosomes protein 1AHomo sapiens (human)Kd30.000011
Structural maintenance of chromosomes protein 2Homo sapiens (human)Kd30.000011
TGF-beta receptor type-1Homo sapiens (human)Kd30.000012
TGF-beta receptor type-2Homo sapiens (human)Kd30.000011
Thyroid hormone receptor-associated protein 3Homo sapiens (human)Kd30.000012
TRAF2 and NCK-interacting protein kinaseHomo sapiens (human)Kd30.000011
Tyrosine--tRNA ligase, cytoplasmicHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase ABL1Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase ABL2Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase BTKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase CSKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FerHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase Fes/FpsHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FgrHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FRKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase FynHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase HCKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase JAK1Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase JAK2Homo sapiens (human)Kd30.000011
Tyrosine-protein kinase LckHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase LynHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase MerHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase SYKHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase TecHomo sapiens (human)Kd30.000011
Tyrosine-protein kinase YesHomo sapiens (human)Kd30.000011
U5 small nuclear ribonucleoprotein 200 kDa helicaseHomo sapiens (human)Kd30.000011
Uncharacterized aarF domain-containing protein kinase 5Homo sapiens (human)Kd30.000011
Uncharacterized protein FLJ45252Homo sapiens (human)Kd30.000011
Very long-chain specific acyl-CoA dehydrogenase, mitochondrialHomo sapiens (human)Kd30.000011
Wee1-like protein kinaseHomo sapiens (human)Kd30.000011