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sulfamides

Compounds where two amino groups are bound to an SO2 unit.

ChEBI ID: 51871

Members (9)

MemberDefinitionRole
act-132577A member of the class of sulfamides in which one of the amino groups of sulfonamide is substituted by a 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl group. An active metabolite of macitentan (obtained by oxidative depropylation), an orphan drug used for the treatment of pulmonary arterial hypertension.ACT-132577
cyazofamidA member of the class of imidazoles carrying dimethylsulfamyl, cyano, chloro and 4-tolyl substituents at positions 1, 2, 4 and 5 respectively. A fungicide used mainly for controlling Oomycete and Plasmodiophora diseases on potatoes and tomatoes. It is a skin and eye irritant and is moderately toxic to birds, most aquatic organisms, honeybees and earthworms.cyazofamid
dichlofluanidA member of the class of sulfamides that is sulfamide in which the hydrogens attached to one of the nitrogens are replaced by methyl groups, while those attached to the other nitrogen are replaced by a phenyl and a [dichloro(fluoro)methyl]sulfanediyl group. A fungicide introduced in 1965 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union.dichlofluanid
macitentanA member of the class of sulfamides in which the two amino groups of sulfonamide are substituted by 5-(4-bromophenyl)-6-{2-[(5-bromopyrimidin-2-yl)oxy]ethoxy}pyrimidin-4-yl and propyl groups. An orphan drug used for the treatment of pulmonary arterial hypertension.macitentan
mesulergineA member of the class of ergot alkaloids that is known to act on serotonin and dopamine receptors.mesulergine
n-dichlorofluoromethylthio-n',n'-dimethyl-n-p-tolylsulfamideA member of the class of sulfamides that is dichlofluanid in which the hydrogen at the para position of the phenyl group is replaced by a methyl group. A fungicide first marketed in 1971 and used in the cultivation of fruit and vegetables, as well as in wood preservatives, it is no longer approved for use in the European Union.tolylfluanid
N,N-dimethyl-N'-p-tolylsulfamideA member of the class of sulfamides that is N,N-dimethylsulfuric diamide substituted by a 4-methylphenyl group at the amino nitrogen atom. It is a metabolite of the agrochemical tolylfluanid.N,N-dimethyl-N'-p-tolylsulfamide
ro5126766A member of the class of coumarins that is 4-methyl-7-[(pyrimidin-2-yl)oxy]coumarin carrying an additional [2-[(methylaminosulfonyl)amino]-3-fluoropyridin-4-yl]methyl substituent at position 3.CH5126766
sulfamideThe simplest of the sulfamic acids consisting of a single sulfur atom covalently bound by single bonds to two amino groups and by double bonds to two oxygen atoms.sulfamide

Research

Studies (653)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199077 (11.79)18.7374
1990's126 (19.30)18.2507
2000's89 (13.63)29.6817
2010's262 (40.12)24.3611
2020's99 (15.16)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials62 (8.81%)5.53%
Reviews59 (8.38%)6.00%
Case Studies28 (3.98%)4.05%
Observational5 (0.71%)0.25%
Other550 (78.13%)84.16%