Drug-Induced Cochlear Toxicity

A condition associated with the use of certain medications (e.g., AMINOGLYCOSIDES and CISPLATIN) that cause functional impairments of the INNER EAR characterized by transient or permanent dysequilibrium, HEARING LOSS, and/or TINNITUS.

Synonym
Drug-Induced Cochleotoxicity
Drug-Induced Cochlear Toxicity
Drug-Induced Otological Toxicity
Drug-Induced Ototoxicity
Drug-Related Ototoxicity
Drug-Related Cochlear Toxicity
Drug-Related Cochleotoxicity
Drug-Induced Vestibulotoxicity
Drug-Induced Vestibular Toxicity
Drug-Related Otological Toxicity

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	0 (0.00)	23.3326
1990's	0 (0.00)	12.5806
2000's	0 (0.00)	18.1394
2010's	36 (13.58)	28.8240
2020's	229 (86.42)	9.53

Drug	Relationship Strength	Studies	Trials
carnitine	low	1	0
chlorine	low	2	0
guaiacol	low	1	0
thioctic acid	low	1	0
melatonin	low	2	0
niacinamide	low	1	0
thiosulfates	low	4	0
urea	low	1	0
sk&f-38393	low	1	0
acetaminophen	low	1	0
amifostine anhydrous	low	2	0
aspirin	low	1	0
berberine	low	3	0
bumetanide	low	1	0
chloroquine	low	3	0
ciprofloxacin	low	2	0
eflornithine	medium	1	1
disulfiram	low	1	0
ebselen	low	1	0
furosemide	low	5	0
gentamicin	medium	31	1
hydroxychloroquine	low	5	0
beta-lapachone	low	1	0
merbromin	low	1	0
metformin	low	2	0
nimodipine	low	1	0
phenobarbital	low	1	0
aspartic acid	low	1	0
kanamycin a	low	11	0
bromodeoxyuridine	low	1	0
phenylethyl alcohol	low	1	0
methionine	medium	1	1
mannitol	low	3	0
arginine	low	1	0
methylprednisolone	low	1	0
quinoxalines	low	2	0
xanthenes	low	1	0
trehalose	low	1	0
styrene	low	1	0
acrolein	low	1	0
thiophenes	low	1	0
3,3'-iminodipropionitrile	low	2	0
framycetin	low	11	0
ditiocarb	low	1	0
catechin	low	1	0
thiamine pyrophosphate	low	1	0
pyrazines	low	1	0
kainic acid	low	2	0
acetylcysteine	medium	6	1
ethyl pyruvate	low	2	0
2-piperidone	low	1	0
tetramethylpyrazine	low	1	0
vancomycin	low	3	0
2-tert-butylhydroquinone	low	1	0
n-methylaspartate	low	1	0
3,5,6-trichloro-2-pyridinol	low	1	0
platinum	low	12	0
cadmium	low	1	0
gadolinium	low	1	0
hypochlorous acid	low	1	0
sodium thiosulfate	low	6	0
cromolyn sodium	low	1	0
calcium dobesilate	low	1	0
zingerone	low	1	0
amoxicillin	low	1	0
tobramycin	low	7	0
amikacin	low	10	0
diltiazem	low	1	0
colforsin	low	1	0
fomesafen	low	1	0
lovastatin	low	1	0
atorvastatin	medium	1	1
glucose, (beta-d)-isomer	low	3	0
chloroquine diphosphate	low	1	0
baicalin	low	1	0
epigallocatechin gallate	low	1	0
n-acetylaspartic acid	low	1	0
telmisartan	low	1	0
3,4-dihydroxyphenylethanol	low	1	0
aucubin	low	1	0
homocysteine	low	1	0
tanshinone	low	1	0
methotrexate	low	2	0
benzofurans	low	1	0
taurochenodeoxycholic acid	low	1	0
povidone-iodine	low	1	0
carboplatin	low	13	0
taxifolin	low	1	0
nicotinamide-beta-riboside	low	1	0
netilmicin	low	1	0
linezolid	low	1	0
tretinoin	low	1	0
3-hydroxy-3-methylglutaryl-coenzyme a	low	1	0
resveratrol	low	3	0
tacrolimus	low	1	0
ferulic acid	low	2	0
zithromax	low	1	0
texas red	low	1	0
riboflavin	low	1	0
stilbenes	low	3	0
s 1033	low	1	0
rg108	low	1	0
curcumin	low	2	0
capsaicin	low	1	0
quinine	low	2	0
sch 23390	low	1	0
apramycin	low	1	0
gentamicin c	low	1	0
ginsenosides	low	1	0
sb 225002	low	1	0
ferrostatin-1	low	2	0
naphthoquinones	low	1	0
am 630	low	1	0
quercetin	low	2	0
bilirubin	low	2	0
amphotericin b	low	1	0
astaxanthine	low	3	0
lutein	low	1	0
pterostilbene	low	1	0
chicoric acid	low	1	0
4-hydroxy-2-nonenal	low	1	0
5,7-dihydroxy-4-methylcoumarin	low	1	0
puerarin	low	1	0
2,3,5,4'-tetrahydroxystilbene 2-o-glucopyranoside	low	2	0
salvianolic acid B	low	1	0
beta-escin	low	1	0
chlorhexidine	low	3	0
s 1743	low	1	0
dexlansoprazole	low	1	0
cabazitaxel	low	1	0
3,5-bis(2-fluorobenzylidene)piperidin-4-one	low	1	0
etimicin	low	1	0
sb 743921	low	1	0
pasireotide	low	1	0
acebutolol	low	1	0
losartan potassium	low	1	0
ginsenoside rh1	low	1	0
mefloquine	low	1	0
nad	low	2	0
cellulose	low	1	0
sodium salicylate	low	2	0
chitosan	low	1	0
apelin-13 peptide	low	1	0
salicylates	low	1	0
cyclosporine	low	1	0
folic acid	low	1	0
rifampin	low	1	0
liproxstatin-1	low	1	0
mitosox red	low	1	0

Protein Targets (1,812)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Alcohol dehydrogenase E chain	0	1	0	1
Alcohol dehydrogenase S chain	0	1	0	1
Peptidyl-prolyl cis-trans isomerase FKBP5	0	1	1	2
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	28	0	0	28
Chain A, HADH2 protein	25	0	0	25
Chain B, HADH2 protein	25	0	0	25
Luciferase	18	0	0	18
interleukin 8	10	0	0	10
acetylcholinesterase	13	0	0	13
15-lipoxygenase, partial	17	0	0	17
phosphopantetheinyl transferase	24	0	0	24
RAR-related orphan receptor gamma	29	0	0	29
USP1 protein, partial	20	0	0	20
GLS protein	21	0	0	21
TDP1 protein	39	0	0	39
GLI family zinc finger 3	28	0	0	28
AR protein	44	0	0	44
aldehyde dehydrogenase 1 family, member A1	38	0	0	38
estrogen receptor 2 (ER beta)	22	0	0	22
nuclear receptor subfamily 1, group I, member 3	30	0	0	30
cytochrome P450 family 3 subfamily A polypeptide 4	21	0	0	21
glucocorticoid receptor [Homo sapiens]	30	0	0	30
retinoic acid nuclear receptor alpha variant 1	28	0	0	28
retinoid X nuclear receptor alpha	33	0	0	33
estrogen-related nuclear receptor alpha	37	0	0	37
pregnane X nuclear receptor	28	0	0	28
estrogen nuclear receptor alpha	54	0	0	54
G	15	0	0	15
cytochrome P450 2D6	17	0	0	17
peroxisome proliferator-activated receptor delta	22	0	0	22
peroxisome proliferator activated receptor gamma	26	0	0	26
vitamin D (1,25- dihydroxyvitamin D3) receptor	23	0	0	23
euchromatic histone-lysine N-methyltransferase 2	40	0	0	40
aryl hydrocarbon receptor	22	0	0	22
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	20	0	0	20
activating transcription factor 6	17	0	0	17
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	11	0	0	11
v-jun sarcoma virus 17 oncogene homolog (avian)	12	0	0	12
Histone H2A.x	13	0	0	13
cytochrome P450 2C9 precursor	8	0	0	8
vitamin D3 receptor isoform VDRA	17	0	0	17
thyroid hormone receptor beta isoform a	14	0	0	14
potassium voltage-gated channel subfamily H member 2 isoform d	12	0	0	12
thyroid hormone receptor beta isoform 2	31	0	0	31
heat shock protein beta-1	11	0	0	11
huntingtin isoform 2	8	0	0	8
nuclear factor erythroid 2-related factor 2 isoform 1	35	0	0	35
nuclear receptor ROR-gamma isoform 1	18	0	0	18
geminin	39	0	0	39
peripheral myelin protein 22	20	0	0	20
lethal factor (plasmid)	17	0	0	17
lamin isoform A-delta10	30	0	0	30
Nuclear receptor subfamily 1 group I member 2	0	0	6	6
Voltage-dependent calcium channel gamma-2 subunit	19	0	0	19
Interferon beta	22	0	0	22
HLA class I histocompatibility antigen, B alpha chain	15	0	0	15
Cellular tumor antigen p53	29	0	0	29
Tyrosinase	0	4	0	4
Glutamate receptor 2	20	3	1	24
Histamine H2 receptor	13	0	0	14
Nuclear receptor ROR-gamma	15	1	1	17
Nuclear factor erythroid 2-related factor 2	0	0	3	7
Inositol hexakisphosphate kinase 1	15	0	0	15
cytochrome P450 2C9, partial	15	0	0	15
Polyunsaturated fatty acid 5-lipoxygenase	0	6	0	6
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	1	1	2
RAF proto-oncogene serine/threonine-protein kinase	0	2	1	3
Ribosomal protein S6 kinase beta-1	0	1	1	2
Mitogen-activated protein kinase 1	0	2	1	3
RAC-alpha serine/threonine-protein kinase	0	3	1	4
RAC-beta serine/threonine-protein kinase	0	1	1	2
Vascular endothelial growth factor receptor 2	0	2	1	3
MAP kinase-activated protein kinase 2	0	1	1	2
5'-AMP-activated protein kinase subunit gamma-1	0	1	1	2
Dual specificity mitogen-activated protein kinase kinase 1	0	2	1	3
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	1	1	2
Mitogen-activated protein kinase 14	0	4	2	6
Serine/threonine-protein kinase Nek1	0	1	1	2
5'-AMP-activated protein kinase subunit beta-1	0	1	0	1
SMAD family member 2	13	0	0	13
SMAD family member 3	13	0	0	13
histone deacetylase 9 isoform 3	6	0	0	6
Microtubule-associated protein tau	25	0	0	25
Transient receptor potential cation channel subfamily A member 1	0	2	2	4
acid sphingomyelinase	5	0	0	5
thioredoxin reductase	24	0	0	24
hypoxia-inducible factor 1 alpha subunit	10	0	0	10
thyroid stimulating hormone receptor	23	0	0	23
farnesoid X nuclear receptor	21	0	0	21
glucocerebrosidase	10	0	0	10
thyroid stimulating hormone receptor	14	0	0	14
tumor necrosis factor	3	0	0	3
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	17	0	0	17
importin subunit beta-1 isoform 1	5	0	0	5
nuclear factor NF-kappa-B p105 subunit isoform 1	5	0	1	6
snurportin-1	5	0	0	5
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase kappa isoform 1	19	0	0	19
cytochrome P450 3A4 isoform 1	20	0	0	20
caspase-1 isoform alpha precursor	5	0	0	5
Gamma-aminobutyric acid receptor subunit pi	20	1	0	21
Carbonic anhydrase 12	0	9	0	11
Rap guanine nucleotide exchange factor 3	5	0	0	5
Carbonic anhydrase 1	0	15	0	18
Carbonic anhydrase 2	0	16	1	20
Aldo-keto reductase family 1 member B1	0	9	0	9
Gamma-aminobutyric acid receptor subunit beta-1	20	1	0	21
Gamma-aminobutyric acid receptor subunit delta	20	1	0	21
Gamma-aminobutyric acid receptor subunit gamma-2	20	1	0	21
Gamma-aminobutyric acid receptor subunit alpha-5	20	1	0	21
Gamma-aminobutyric acid receptor subunit alpha-3	20	1	0	21
Gamma-aminobutyric acid receptor subunit gamma-1	20	1	0	21
Gamma-aminobutyric acid receptor subunit alpha-2	20	1	0	21
Genome polyprotein	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	20	1	0	21
Gamma-aminobutyric acid receptor subunit gamma-3	20	1	0	21
Gamma-aminobutyric acid receptor subunit alpha-6	20	1	0	21
Caspase-7	5	0	0	5
Gamma-aminobutyric acid receptor subunit alpha-1	20	2	0	22
Gamma-aminobutyric acid receptor subunit beta-3	20	1	0	21
Gamma-aminobutyric acid receptor subunit beta-2	20	1	0	21
Carbonic anhydrase 9	0	9	0	11
GABA theta subunit	20	1	0	21
Gamma-aminobutyric acid receptor subunit epsilon	20	1	0	21
ATAD5 protein, partial	15	0	0	15
Smad3	9	0	0	9
progesterone receptor	20	0	0	20
EWS/FLI fusion protein	21	0	0	22
chromobox protein homolog 1	23	0	0	23
ATP-binding cassette sub-family C member 3	0	28	0	28
Multidrug resistance-associated protein 4	0	29	0	31
Solute carrier family 22 member 6	0	5	0	5
UDP-glucuronosyltransferase 1A9	0	0	0	1
Bile salt export pump	0	6	0	7
Bile salt export pump	0	39	0	40
Cytochrome P450 2B1	0	0	0	1
Cytochrome P450 1A1	0	0	0	1
Myoglobin	0	1	0	1
Cytochrome P450 1A1	0	5	2	8
Cytochrome P450 1A2	0	8	1	12
Prostaglandin G/H synthase 1	0	4	2	6
Carbonic anhydrase 3	0	7	0	7
Cytochrome P450 3A4	0	13	1	18
Cytochrome P450 2D6	0	8	1	11
Cytochrome P450 2C9	0	11	1	14
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
Sulfotransferase 1A1	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	0	0	1
Arachidonate 5-lipoxygenase-activating protein	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	0	0	1
Carbonic anhydrase 4	0	11	0	13
Prostaglandin G/H synthase 1	0	9	0	9
Carbonic anhydrase 6	0	9	0	11
Carbonic anhydrase 5A, mitochondrial	0	8	0	10
Prostaglandin G/H synthase 2	0	10	1	12
Carbonic anhydrase 7	0	8	0	10
Cytochrome P450 2J2	0	7	0	7
Canalicular multispecific organic anion transporter 1	0	26	0	26
Carbonic anhydrase 15	0	4	0	4
Carbonic anhydrase 13	0	6	0	8
Carbonic anhydrase 14	0	7	0	9
Carbonic anhydrase 5B, mitochondrial	0	7	0	9
toxin B	0	0	0	1
Chain A, JmjC domain-containing histone demethylation protein 3A	8	0	0	8
Chain A, 2-oxoglutarate Oxygenase	27	0	0	27
Chain A, ATP-DEPENDENT DNA HELICASE Q1	10	0	0	10
dopamine D1 receptor	5	0	0	5
pregnane X receptor	9	0	0	9
NFKB1 protein, partial	7	0	0	7
Thrombopoietin	5	0	0	5
regulator of G-protein signaling 4	13	0	0	13
arylsulfatase A	9	0	0	9
Bloom syndrome protein isoform 1	17	0	0	17
D(1A) dopamine receptor	7	0	0	7
flap endonuclease 1	14	0	0	14
survival motor neuron protein isoform d	12	0	0	12
muscarinic acetylcholine receptor M1	10	0	0	10
Histone deacetylase 3	0	2	0	2
Histone deacetylase 4	0	2	0	2
Guanine nucleotide-binding protein G	4	0	0	4
Histone deacetylase 1	0	5	0	5
Histone deacetylase 7	0	2	0	2
Histone deacetylase 2	0	5	0	5
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Ataxin-2	15	0	0	15
Histone deacetylase 8	0	3	0	3
Histone deacetylase 6	0	5	0	5
Histone deacetylase 9	0	3	0	3
Histone deacetylase 5	0	3	0	3
ATP-dependent phosphofructokinase	19	0	0	19
Transient receptor potential cation channel subfamily A member 1	0	1	3	4
Chain A, Cruzipain	15	0	0	15
Solute carrier family 22 member 2	0	3	0	5
Solute carrier family 22 member 1	0	6	0	6
Polyamine oxidase 1	0	1	0	1
Solute carrier family 22 member 3	0	2	0	3
Solute carrier family 22 member 3	0	0	0	1
Alpha-2B adrenergic receptor	0	2	0	2
Alpha-2C adrenergic receptor	0	2	0	2
Alpha-2A adrenergic receptor	0	2	0	2
Nischarin	0	1	0	1
Solute carrier family 22 member 1	0	3	0	5
Deoxyhypusine synthase	0	1	0	1
Solute carrier family 22 member 2	0	2	0	3
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	24	0	0	24
Fumarate hydratase	6	0	0	6
PPM1D protein	10	0	0	10
polyprotein	6	0	0	6
cellular tumor antigen p53 isoform a	13	0	0	13
Polyunsaturated fatty acid lipoxygenase ALOX15B	10	1	0	11
Integrin beta-3	11	1	0	12
Integrin alpha-IIb	11	1	0	12
Androgen receptor	0	6	0	6
Cannabinoid receptor 1	0	5	0	5
Cannabinoid receptor 2	0	4	1	5
Cannabinoid receptor 2	0	0	1	1
Inositol monophosphatase 1	9	0	0	9
D(3) dopamine receptor	0	4	0	4
Spike glycoprotein	14	3	4	21
histone acetyltransferase KAT2A isoform 1	13	0	0	13
Aminoglycoside 3'-phosphotransferase	0	0	0	2
Chain A, Beta-lactamase	11	0	0	11
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
apical membrane antigen 1, AMA1	4	0	0	4
Beta-lactamase	0	0	0	1
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	7	0	0	7
DNA polymerase iota isoform a (long)	17	0	0	17
urokinase-type plasminogen activator precursor	9	0	0	9
plasminogen precursor	9	0	0	9
urokinase plasminogen activator surface receptor precursor	9	0	0	9
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase SHV-1	0	0	0	1
Beta-lactamase	0	0	0	1
Kappa-type opioid receptor	0	1	0	2
Solute carrier family 15 member 1	0	1	0	1
Solute carrier family 15 member 1	0	1	0	1
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Beta-lactamase	0	0	0	1
Beta-lactamase	0	0	0	1
Cytochrome P450 2C19	0	5	1	8
Potassium voltage-gated channel subfamily H member 2	0	11	0	12
Aurora kinase B	0	3	1	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	12	1	14
Apelin receptor	0	1	1	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	1	1
alpha-galactosidase	5	0	0	5
cytochrome P450 2C19 precursor	10	0	0	10
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	2	0	3
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
Chain A, Ferritin light chain	16	0	0	16
Metabotropic glutamate receptor 6	0	0	2	2
Excitatory amino acid transporter 4	0	1	0	1
Glutamate transporter homolog	0	0	1	1
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	1
Glutamate receptor ionotropic, NMDA 1	1	5	2	9
Excitatory amino acid transporter 1	0	1	0	1
Excitatory amino acid transporter 2	0	1	0	1
Excitatory amino acid transporter 3	0	1	0	1
Glutamate receptor ionotropic, NMDA 2A	1	5	2	9
Glutamate receptor ionotropic, NMDA 2B	1	5	2	9
Glutamate receptor ionotropic, NMDA 2C	1	5	2	9
Metabotropic glutamate receptor 1	0	0	1	1
Metabotropic glutamate receptor 2	0	0	1	1
Carbonic anhydrase-like protein, putative	0	0	0	1
Glutamate receptor ionotropic, NMDA 2D	1	5	2	9
Glutamate receptor ionotropic, NMDA 3B	1	5	2	9
Carbonic anhydrase 4	0	0	0	1
Glutamate receptor ionotropic, NMDA 3A	1	5	2	9
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	4	0	0	4
Rac1 protein	0	0	1	1
IDH1	14	0	0	14
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	1	0	1
Prostaglandin G/H synthase 1	0	3	0	3
Prostaglandin G/H synthase 2	0	1	0	1
Epidermal growth factor receptor	0	3	1	4
Fatty acid-binding protein, liver	0	1	0	1
Myeloperoxidase	0	3	0	3
Seed linoleate 13S-lipoxygenase-1	0	2	0	4
Glutathione hydrolase 1 proenzyme	0	1	0	1
Adenosine receptor A1	1	4	0	5
Adenosine receptor A2a	0	6	0	6
Substance-P receptor	0	3	0	3
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Prostaglandin G/H synthase 2	0	3	0	3
Rho-associated protein kinase 2	0	1	0	1
Nicotinate phosphoribosyltransferase	0	1	0	1
Solute carrier family 22 member 20	0	3	0	3
Solute carrier family 22 member 6	0	3	0	3
Sigma non-opioid intracellular receptor 1	1	3	1	5
Sigma non-opioid intracellular receptor 1	0	0	1	1
caspase 7, apoptosis-related cysteine protease	8	0	0	8
caspase-3	8	0	0	8
Caspase-7	4	0	0	4
caspase-3	4	0	0	4
Solute carrier organic anion transporter family member 2B1	0	2	0	3
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	3	0	3
ATP-dependent translocase ABCB1	0	10	2	15
Insulin receptor	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	2	0	2
Solute carrier organic anion transporter family member 1B3	0	8	0	12
Solute carrier organic anion transporter family member 1B1	0	11	0	14
lethal(3)malignant brain tumor-like protein 1 isoform I	3	0	0	3
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Lysine-specific histone demethylase 1A	0	8	0	8
Cyclin-dependent kinase 1	0	3	1	4
Trypsin-1	0	2	0	2
Trypsin-2	0	2	0	2
Replicase polyprotein 1ab	0	12	5	17
Replicase polyprotein 1ab	0	14	7	21
G2/mitotic-specific cyclin-B1	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Dipeptidyl peptidase 4	0	6	0	6
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
5-hydroxytryptamine receptor 7	0	1	0	1
Trypsin-3	0	2	0	2
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-2	0	1	0	1
Prolyl endopeptidase	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Serine/threonine-protein kinase PLK1	0	2	1	3
Gamma-aminobutyric acid receptor subunit epsilon	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Chain A, Putative fructose-1,6-bisphosphate aldolase	12	0	0	12
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	12	0	0	12
cytochrome P450 2D6 isoform 1	7	0	0	7
Telomerase reverse transcriptase	0	2	0	2
Acetylcholinesterase	0	7	0	7
Neuraminidase	0	2	0	2
Neuraminidase	0	1	0	1
Cholinesterase	0	6	0	6
Tyrosine-protein phosphatase non-receptor type 1	0	4	1	5
Acetylcholinesterase	0	11	0	11
Aldo-keto reductase family 1 member C3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Cholinesterase	0	5	0	5
Cytochrome P450 1B1	0	8	1	9
Lysine-specific demethylase 4E	0	2	0	2
67.9K protein	11	0	0	11
Parkin	9	0	0	9
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	6	0	0	6
galactokinase	3	0	0	3
hexokinase-4 isoform 1	4	0	0	4
peripheral myelin protein 22 isoform 1	9	0	0	9
glucokinase regulatory protein	4	0	0	4
mitogen-activated protein kinase 1	9	0	0	9
atrial natriuretic peptide receptor 2 precursor	4	0	0	4
ras-related protein Rab-9A	5	0	0	5
serine/threonine-protein kinase mTOR isoform 1	5	0	0	5
M-phase phosphoprotein 8	10	0	0	10
muscleblind-like protein 1 isoform 1	8	0	0	8
neuropeptide S receptor isoform A	9	0	0	9
Cocaine esterase	0	2	0	2
Tyrosyl-DNA phosphodiesterase 2	0	1	0	1
Amyloid-beta precursor protein	3	8	1	13
60 kDa chaperonin	0	5	0	5
60 kDa heat shock protein, mitochondrial	0	8	0	8
Indoleamine 2,3-dioxygenase 1	0	3	0	3
NAD	0	1	0	1
NADPH--cytochrome P450 reductase	0	1	0	1
Protein kinase C alpha type	0	2	2	4
Nuclear factor NF-kappa-B p105 subunit	0	2	0	2
Protein-glutamine gamma-glutamyltransferase 2	0	1	0	1
Liver carboxylesterase 1	0	2	0	2
Caspase-1	0	4	0	4
M-phase inducer phosphatase 1	0	1	0	1
Alpha-synuclein	6	5	1	12
Tyrosine-protein kinase JAK3	0	1	1	2
10 kDa heat shock protein, mitochondrial	0	8	0	8
Nuclear factor NF-kappa-B p100 subunit	0	2	0	2
Transcription factor p65	0	2	0	2
Receptor-type tyrosine-protein phosphatase eta	0	1	0	1
Thiosulfate sulfurtransferase	0	7	0	7
Receptor protein-tyrosine kinase	0	1	0	1
60 kDa chaperonin	0	8	0	8
10 kDa chaperonin	0	8	0	8
Single-stranded DNA cytosine deaminase	1	0	0	1
Mucosa-associated lymphoid tissue lymphoma translocation protein 1	0	1	0	1
phosphoglycerate kinase	2	0	0	2
Aldo-keto reductase family 1 member B10	0	1	0	1
Aldo-keto reductase family 1 member B1	0	6	0	6
CPG DNA methylase	0	3	0	3
Sodium-dependent dopamine transporter	0	2	0	2
Multidrug resistance protein CDR1	0	1	0	1
Lactoylglutathione lyase	0	4	0	4
Integrase	0	6	1	7
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	1	1	2
bromodomain adjacent to zinc finger domain 2B	11	0	0	11
nuclear receptor subfamily 1, group I, member 2	5	0	0	5
Nuclear hormone receptor family member daf-12	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	12	0	0	12
oxysterols receptor LXR-beta isoform 1	0	0	1	1
Thymidine kinase, cytosolic	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase	0	0	0	1
Thymidylate kinase	0	1	0	1
ATPase family AAA domain-containing protein 5	12	0	0	12
ubiquitin carboxyl-terminal hydrolase 2 isoform a	3	0	0	3
Solute carrier family 12 member 2	0	1	0	1
Disintegrin and metalloproteinase domain-containing protein 17	3	1	0	4
transient receptor potential cation channel subfamily V member 1	2	0	0	2
Transient receptor potential cation channel subfamily V member 1	0	2	1	3
NADH-ubiquinone oxidoreductase chain 1	0	1	0	1
D(2) dopamine receptor	0	4	3	8
Potassium voltage-gated channel subfamily A member 1	0	2	0	2
Corticotropin-releasing factor receptor 2	0	1	0	1
Transient receptor potential cation channel subfamily V member 1	0	3	1	5
Transient receptor potential cation channel subfamily V member 4	0	0	1	1
Transient receptor potential cation channel subfamily V member 2	0	0	1	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	6	0	0	6
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
Solute carrier family 22 member 16	0	0	0	1
Solute carrier family 22 member 21	0	0	0	1
Solute carrier family 22 member 5	0	0	0	1
DNA polymerase beta	12	0	0	12
Arginase	0	3	0	3
Pancreatic triacylglycerol lipase	0	3	0	3
Prothrombin	0	2	2	4
Sucrase-isomaltase, intestinal	0	2	0	2
Mu-type opioid receptor	0	2	0	4
Delta-type opioid receptor	0	0	0	2
Kappa-type opioid receptor	0	2	0	4
Xanthine dehydrogenase/oxidase	0	4	0	4
Melatonin receptor type 1A	0	2	2	4
Melatonin receptor type 1B	0	2	2	4
Death-associated protein kinase 1	0	3	1	4
Beta-secretase 1	0	6	0	6
Carbonic anhydrase 3	0	2	0	2
Dihydroorotate dehydrogenase	0	2	0	2
Tyrosine-protein phosphatase YopH	0	2	0	2
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
PAX8	0	0	0	1
glp-1 receptor, partial	9	0	0	9
PINK1	3	0	0	3
heat shock protein 90	0	0	1	1
calcineurin A1, putative	0	0	1	1
hepatocyte nuclear factor 4-alpha isoform 2	0	1	0	1
perilipin-5	0	4	0	4
perilipin-1	0	4	0	4
transcriptional regulator ERG isoform 3	4	0	0	4
ubiquitin-conjugating enzyme E2 N	0	1	0	1
protein AF-9 isoform a	0	0	0	1
melanocortin receptor 4	0	1	0	1
CAAX prenyl protease	0	0	0	1
bcl-2-related protein A1	0	2	0	2
1-acylglycerol-3-phosphate O-acyltransferase ABHD5 isoform a	0	4	0	4
glycogen synthase kinase-3 alpha	0	0	0	1
hexokinase HKDC1	0	1	1	2
DNA repair protein RAD52 homolog isoform a	0	0	0	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Synaptojanin-2	0	1	0	1
Synaptojanin-1	0	1	0	1
Glutathione reductase, mitochondrial	0	2	0	3
72 kDa type IV collagenase	0	4	0	4
Matrix metalloproteinase-9	0	3	0	3
Trypanothione reductase	0	1	0	1
TAR DNA-binding protein 43	12	0	0	12
Peroxisomal N(1)-acetyl-spermine/spermidine oxidase	0	1	0	1
Multidrug and toxin extrusion protein 2	0	1	0	1
Rap guanine nucleotide exchange factor 4	5	0	0	5
Multidrug and toxin extrusion protein 1	0	4	0	4
Spermine oxidase	0	1	0	1
Carbonic anhydrase	0	1	0	1
glucose-6-phosphate dehydrogenase-6-phosphogluconolactonase	0	3	0	3
Spike glycoprotein	0	3	4	7
Replicase polyprotein 1ab	0	4	4	8
glucose-6-phosphate 1-dehydrogenase isoform b	0	3	0	3
Transmembrane protease serine 2	0	3	4	7
Dihydrofolate reductase	0	2	0	2
DNA ligase	0	1	0	1
Riboflavin-binding protein	0	1	2	3
Major prion protein	0	0	1	1
Histidine-rich protein PFHRP-II	0	2	0	3
Procathepsin L	0	3	4	7
Muscarinic acetylcholine receptor M2	0	3	0	3
Muscarinic acetylcholine receptor M4	0	2	0	2
Muscarinic acetylcholine receptor M5	0	2	0	2
Alpha-2A adrenergic receptor	0	5	0	5
Replicase polyprotein 1a	0	5	4	9
Replicase polyprotein 1ab	0	3	4	7
Spike glycoprotein	0	1	0	1
Muscarinic acetylcholine receptor M1	0	2	0	2
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	7	2	9
Alpha-2B adrenergic receptor	0	4	0	4
Alpha-2C adrenergic receptor	0	3	1	4
DNA ligase 1	0	1	0	1
Muscarinic acetylcholine receptor M3	0	2	0	2
Serine/threonine-protein kinase mTOR	0	2	1	3
Nuclear receptor subfamily 4 group A member 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
MO15-related protein kinase Pfmrk	0	2	0	2
DNA ligase A	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Phosphoethanolamine N-methyltransferase	0	1	0	1
Angiotensin-converting enzyme 2	0	3	4	7
Cysteine proteinase falcipain 2a	0	1	0	1
Cysteine proteinase falcipain 2a	0	1	0	1
endonuclease IV	3	0	0	3
GALC protein	1	0	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	2
DNA gyrase subunit A	0	2	0	4
DNA gyrase subunit B	0	2	0	4
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	2
DNA topoisomerase 2-alpha	0	1	1	5
DNA gyrase subunit A	0	1	0	2
Multidrug resistance protein MdtK	0	0	1	1
DNA gyrase subunit B	0	2	0	2
DNA gyrase subunit A	0	2	0	2
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
DNA topoisomerase 4 subunit A	0	1	0	1
DNA topoisomerase 4 subunit B	0	1	0	1
nuclear receptor subfamily 0 group B member 1	0	1	0	1
steroidogenic factor 1	0	1	0	1
relaxin receptor 1 isoform 1	1	0	0	1
relaxin receptor 2 isoform 1	1	0	0	1
5-hydroxytryptamine receptor 1A	0	1	1	2
Solute carrier family 2, facilitated glucose transporter member 1	0	1	1	2
Adenylate cyclase type 2	0	0	1	1
Adenylate cyclase type 8	0	1	1	2
Adenylate cyclase type 1	0	2	1	3
Relaxin receptor 1	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	2	2
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Proton-coupled amino acid transporter 1	0	1	0	1
Alkaline phosphatase, germ cell type	0	1	0	1
G protein-coupled receptor GPR35	0	0	1	1
G-protein coupled receptor 35	0	0	1	1
G-protein coupled receptor 35	0	2	3	5
Chain A, Breast cancer type 1 susceptibility protein	2	0	0	2
Nrf2	3	0	0	3
alkaline phosphatase, intestinal	0	1	0	1
thioredoxin glutathione reductase	7	0	0	7
toll-like receptor 9	0	1	0	1
TPA: protein transporter TIM10	0	2	0	2
thyrotropin-releasing hormone receptor	6	0	0	6
lysosomal alpha-glucosidase preproprotein	6	0	0	6
alkaline phosphatase, tissue-nonspecific isozyme isoform 1 preproprotein	0	1	0	1
hemoglobin subunit beta	1	0	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	5	0	0	5
intestinal alkaline phosphatase precursor	0	1	0	1
pyruvate kinase PKM isoform a	3	0	0	3
tumor susceptibility gene 101 protein	1	0	0	1
GTP-binding nuclear protein Ran isoform 1	1	0	0	1
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	1	2	0	3
alkaline phosphatase, germ cell type preproprotein	0	1	0	1
hypothetical protein SA1422	0	1	0	1
DNA dC->dU-editing enzyme APOBEC-3F isoform a	2	0	0	2
Prostaglandin E synthase	0	2	0	2
D-amino-acid oxidase	0	1	0	1
Phospholipase A2	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	4	0	4
Neuronal proto-oncogene tyrosine-protein kinase Src	0	1	0	1
Heme oxygenase 1	0	2	0	2
Glutathione S-transferase P	0	1	0	1
Microtubule-associated protein tau	0	2	0	3
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	1	0	1
Tissue factor	0	2	0	2
Aminopeptidase N	0	1	0	1
Aminopeptidase N	0	1	0	1
Alpha-1B adrenergic receptor	0	7	0	7
Sarcoplasmic/endoplasmic reticulum calcium ATPase 2	0	2	0	2
Glycogen synthase kinase-3 beta	0	2	0	2
Amine oxidase [flavin-containing] A	0	9	0	9
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
Heme oxygenase 2	0	2	0	2
Alpha-1D adrenergic receptor	0	3	0	3
Amine oxidase [flavin-containing] B	0	7	0	7
Voltage-dependent L-type calcium channel subunit alpha-1D	0	3	0	3
Proteasome subunit beta type-5	0	4	0	4
17-beta-hydroxysteroid dehydrogenase type 2	0	3	0	3
Alpha-1A adrenergic receptor	0	7	0	7
Glycogen synthase kinase-3 beta	0	2	1	3
Voltage-dependent L-type calcium channel subunit alpha-1S	0	3	0	3
Histone acetyltransferase p300	0	2	0	2
Serine/threonine-protein kinase PAK 1	0	2	1	3
5-hydroxytryptamine receptor 4	0	0	1	1
Sodium/bile acid cotransporter	0	1	1	2
Thioredoxin reductase 1, cytoplasmic	0	2	0	2
Thioredoxin reductase 3	0	2	0	2
Sortase A	0	1	0	1
CREB-binding protein	0	2	0	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 3	0	2	0	2
Cysteine protease	0	1	0	1
NACHT, LRR and PYD domains-containing protein 3	0	1	0	1
Thioredoxin reductase 2, mitochondrial	0	2	0	2
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Lymphocyte antigen 96	0	0	1	1
Beta lactamase (plasmid)	0	1	0	1
WD repeat-containing protein 5	0	1	0	1
Histone-lysine N-methyltransferase 2A	0	1	0	1
NAD(+) hydrolase SARM1	0	2	0	2
Cytosolic endo-beta-N-acetylglucosaminidase	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	4	0	4
Sodium channel protein type 1 subunit alpha	0	2	0	2
Sodium channel protein type 4 subunit alpha	0	1	0	1
5-hydroxytryptamine receptor 7	0	2	0	2
Sodium channel protein type 7 subunit alpha	0	1	0	1
Voltage-dependent L-type calcium channel subunit alpha-1D	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1C	0	4	0	4
Sodium channel protein type 5 subunit alpha	0	2	0	2
Sodium channel protein type 9 subunit alpha	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	2	0	2
Sodium channel protein type 3 subunit alpha	0	2	0	2
Sodium channel protein type 11 subunit alpha	0	1	0	1
Sodium channel protein type 8 subunit alpha	0	1	0	1
Sodium channel protein type 10 subunit alpha	0	1	0	1
nonstructural protein 1	6	0	0	6
pyruvate kinase	4	0	0	4
LacZ protein (plasmid)	0	0	1	1
beta-2 adrenergic receptor	2	0	0	2
type-1 angiotensin II receptor	0	1	0	1
atrial natriuretic peptide receptor 1 precursor	2	0	0	2
runt-related transcription factor 1 isoform AML1b	1	0	0	1
core-binding factor subunit beta isoform 2	1	0	0	1
polypyrimidine tract-binding protein 1 isoform a	1	0	0	1
serine/threonine-protein kinase PLK1	3	0	0	3
apelin receptor	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	1
Vpr	1	0	0	1
bifunctional UDP-N-acetylglucosamine pyrophosphorylase/glucosamine-1-phosphate N-acetyltransferase	0	2	0	2
pyruvate kinase PKM isoform b	3	0	0	3
Fatty-acid amide hydrolase 1	0	1	0	1
Carbamate kinase	0	1	0	1
Retinal dehydrogenase 1	0	1	0	1
Aldehyde dehydrogenase, mitochondrial	0	1	0	1
Ornithine decarboxylase	3	1	0	5
Fructose-1,6-bisphosphatase 1	0	1	0	1
Adenosine receptor A3	0	6	0	6
D(2) dopamine receptor	0	5	0	5
D(1A) dopamine receptor	0	5	1	6
D(4) dopamine receptor	0	3	0	3
Sodium-dependent noradrenaline transporter	0	6	2	8
C-X-C chemokine receptor type 2	0	3	0	3
Mitogen-activated protein kinase 3	0	1	1	2
Protein-lysine 6-oxidase	0	1	0	1
Lysine-specific demethylase 5A	0	1	0	1
5-hydroxytryptamine receptor 2B	0	4	0	4
C-C chemokine receptor type 2	0	2	0	2
5-hydroxytryptamine receptor 6	0	2	0	2
C-C chemokine receptor type 4	0	3	0	3
C-C chemokine receptor type 5	0	2	0	2
Gasdermin-D	0	2	0	2
Lysyl oxidase homolog 3	0	1	0	1
Sodium-dependent dopamine transporter	0	6	0	6
NACHT, LRR and PYD domains-containing protein 3	0	2	0	2
Lysyl oxidase homolog 4	0	1	0	1
Histone-lysine N-methyltransferase EHMT2	0	2	0	2
Monoglyceride lipase	0	1	0	1
Gasdermin-D	0	2	0	2
Histone-lysine N-methyltransferase EHMT1	0	2	0	2
Lysyl oxidase homolog 2	0	1	0	1
heat shock protein 90, putative	0	0	0	1
hypothetical protein CAALFM_CR05890CA	0	0	0	2
H3 histone acetyltransferase	0	0	0	2
large T antigen	0	4	0	4
RNA polymerase beta subunit (EC 2.7.7.6), partial	0	1	0	1
RGS12	1	0	0	1
Arrestin, beta 1	0	1	0	1
MPI protein	0	1	0	1
DNA polymerase III, partial	2	0	0	2
isocitrate dehydrogenase 1, partial	2	0	0	2
luciferase	1	0	0	1
TPA: protein transporter TIM23	0	1	0	1
hexokinase	0	3	0	3
hexokinase-1 isoform HKI	0	0	1	1
neutrophil cytosol factor 1	0	1	0	1
phosphomannomutase 2	0	1	0	1
fructose-bisphosphate aldolase A	1	0	0	1
phosphoethanolamine/phosphocholine phosphatase isoform 1	0	1	0	1
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	6	0	0	6
guanine nucleotide-binding protein G(i) subunit alpha-1 isoform 1	1	0	0	1
eukaryotic translation initiation factor 4 gamma 1 isoform 4	0	2	0	2
eukaryotic translation initiation factor 4E isoform 1	0	2	0	2
streptokinase A precursor	0	0	4	4
Sulfhydryl oxidase 1	0	1	0	1
Gamma-butyrobetaine dioxygenase	0	1	1	2
Sodium channel protein type 1 subunit alpha	1	0	0	1
Sodium channel protein type 2 subunit alpha	1	0	0	1
Sodium channel protein type 3 subunit alpha	1	0	0	1
Macrophage migration inhibitory factor	0	2	0	2
Neutrophil cytosol factor 1	0	1	0	1
Insulin-degrading enzyme	0	1	0	1
Urease subunit alpha	0	5	0	5
Toxin B	0	1	0	1
Endothelin receptor type B	2	0	0	2
Endothelin-1 receptor	2	0	0	2
Bifunctional epoxide hydrolase 2	0	2	0	2
Methionine aminopeptidase 2	0	1	0	1
Urease subunit beta	0	5	0	5
UDP-glucose 4-epimerase	0	1	0	1
Structural capsid protein	0	1	0	1
2,3-bisphosphoglycerate-independent phosphoglycerate mutase	1	0	0	1
Mitochondrial 2-oxodicarboxylate carrier	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	0	1	1
Chain A, POLYMERASE PA	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Chain A, Polymerase Pa	0	1	0	1
Genome polyprotein	0	2	0	2
POsterior Segregation	0	0	2	2
Polycomb protein EED	0	1	1	2
NAD kinase	0	2	1	3
Dihydrofolate reductase	0	3	0	5
Urokinase-type plasminogen activator	0	2	0	2
Tissue-type plasminogen activator	0	1	0	1
Transthyretin	0	1	2	3
Polymerase acidic protein	0	1	0	1
Plasminogen activator inhibitor 1	0	1	0	1
Urokinase-type plasminogen activator	0	1	0	1
Heat shock protein HSP 90-beta	0	1	0	1
Neutrophil elastase	0	4	0	4
Hepatocyte growth factor receptor	0	3	1	4
Matrilysin	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH] FabI	0	2	0	2
Alpha-amylase 1A	0	2	0	2
Apoptosis regulator Bcl-2	0	2	0	2
Glucose-6-phosphate 1-dehydrogenase	0	1	0	1
Fatty acid synthase	0	1	0	1
Lethal factor	0	2	0	2
Phosphoglycerate mutase 1	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	3	0	3
Signal transducer and activator of transcription 1-alpha/beta	0	0	1	1
DNA repair protein RAD52 homolog	0	1	0	1
Fatty acid synthase	0	2	0	2
Matrix metalloproteinase-14	0	1	0	1
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase FUT6	0	1	0	1
Squalene monooxygenase	0	1	0	1
6-phosphogluconate dehydrogenase, decarboxylating	0	3	0	3
BH3-interacting domain death agonist	0	1	0	1
Lactoperoxidase	0	1	0	2
Bcl-2-like protein 1	0	2	0	2
Induced myeloid leukemia cell differentiation protein Mcl-1	0	1	0	1
Alpha-(1,3)-fucosyltransferase 7	0	1	0	1
CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	3	1	4
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	1	2
Bcl-2-related protein A1	0	1	0	1
Sigma non-opioid intracellular receptor 1	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Reverse transcriptase/RNaseH	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] reductase	0	1	0	1
MAP kinase-activated protein kinase 5	0	1	1	2
Histone acetyltransferase KAT2B	0	1	0	1
Bcl-2-like protein 2	0	1	0	1
Bcl2-associated agonist of cell death	0	1	0	1
Histone acetyltransferase KAT5	0	1	0	1
Enoyl-acyl-carrier protein reductase	0	4	0	4
3-oxoacyl-acyl-carrier protein reductase	0	2	0	2
Beta-hydroxyacyl-ACP dehydratase precursor (Fatty acid synthesis protein)	0	3	0	3
Bcl-2-like protein 10	0	1	0	1
Zinc finger protein mex-5	0	0	2	2
ClpP	4	0	0	4
Polyphenol oxidase 2	0	6	0	7
Pyruvate kinase PKM	0	2	0	2
Alpha-glucosidase MAL12	0	2	0	2
Xanthine dehydrogenase/oxidase	0	4	0	5
Beta-carbonic anhydrase 1	0	1	0	1
Carbonic anhydrase 2	0	1	0	1
Hyaluronidase-1	0	1	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
Thymidylate synthase	0	4	0	4
Thymidylate synthase	0	3	0	3
Dihydrofolate reductase	0	2	3	5
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	1	0	2
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	1	0	3
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	4	0	4
30S ribosomal protein S7	0	4	0	4
50S ribosomal protein L15	0	4	0	4
50S ribosomal protein L10	0	4	0	4
50S ribosomal protein L11	0	4	0	4
50S ribosomal protein L7/L12	0	4	0	4
50S ribosomal protein L19	0	4	0	4
50S ribosomal protein L1	0	4	0	4
50S ribosomal protein L20	0	4	0	4
50S ribosomal protein L27	0	4	0	4
50S ribosomal protein L28	0	4	0	4
50S ribosomal protein L29	0	4	0	4
50S ribosomal protein L31	0	4	0	4
50S ribosomal protein L31 type B	0	4	0	4
50S ribosomal protein L32	0	4	0	4
50S ribosomal protein L33	0	4	0	4
50S ribosomal protein L34	0	4	0	4
50S ribosomal protein L35	0	4	0	4
50S ribosomal protein L36	0	4	0	4
30S ribosomal protein S10	0	4	0	4
30S ribosomal protein S11	0	4	0	4
30S ribosomal protein S12	0	4	0	4
30S ribosomal protein S13	0	4	0	4
30S ribosomal protein S16	0	4	0	4
30S ribosomal protein S18	0	4	0	4
30S ribosomal protein S19	0	4	0	4
30S ribosomal protein S20	0	4	0	4
30S ribosomal protein S2	0	4	0	4
30S ribosomal protein S3	0	4	0	4
30S ribosomal protein S4	0	4	0	4
30S ribosomal protein S5	0	4	0	4
30S ribosomal protein S8	0	4	0	4
30S ribosomal protein S9	0	4	0	4
50S ribosomal protein L13	0	4	0	4
50S ribosomal protein L14	0	4	0	4
50S ribosomal protein L16	0	4	0	4
50S ribosomal protein L23	0	4	0	4
30S ribosomal protein S15	0	4	0	4
50S ribosomal protein L17	0	4	0	4
50S ribosomal protein L21	0	4	0	4
50S ribosomal protein L30	0	4	0	4
50S ribosomal protein L6	0	4	0	4
30S ribosomal protein S14	0	4	0	4
30S ribosomal protein S17	0	4	0	4
30S ribosomal protein S1	0	4	0	4
50S ribosomal protein L18	0	4	0	4
50S ribosomal protein L2	0	4	0	4
50S ribosomal protein L3	0	4	0	4
50S ribosomal protein L24	0	4	0	4
50S ribosomal protein L4	0	4	0	4
50S ribosomal protein L22	0	4	0	4
50S ribosomal protein L5	0	4	0	4
30S ribosomal protein S21	0	4	0	4
50S ribosomal protein L25	0	4	0	4
50S ribosomal protein L36 2	0	4	0	4
Protein Rev	0	0	2	2
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
Albumin	0	1	3	4
Glucose-6-phosphate 1-dehydrogenase	0	2	0	2
Serum paraoxonase/arylesterase 1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Adenosine receptor A1	0	1	0	1
Corticosteroid 11-beta-dehydrogenase isozyme 1	0	1	0	1
Holo-[acyl-carrier-protein] synthase	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Chain A, Estrogen receptor 1 (alpha)	0	1	0	1
Chain A, Transthyretin	0	0	1	1
Chain A, Transthyretin	0	0	1	1
BRCA1	4	0	0	4
Neuraminidase	0	3	0	3
P53	3	0	0	3
Alpha-mannosidase	0	1	0	1
NPC intracellular cholesterol transporter 1 precursor	3	0	0	3
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
tyrosine-protein kinase Yes	2	0	0	2
Maltase-glucoamylase, intestinal	0	3	0	3
5-hydroxytryptamine receptor 4	0	2	0	2
Steroid hormone receptor ERR2	0	1	0	1
Tyrosine-protein kinase ABL1	0	5	2	9
Triosephosphate isomerase	0	1	0	1
Estrogen receptor	0	3	1	4
Glucocorticoid receptor	0	2	0	3
Sex hormone-binding globulin	0	0	1	1
Tyrosine-protein kinase Fyn	0	1	1	2
Androgen receptor	0	2	0	3
Sialidase	0	2	0	2
Tyrosinase	0	4	0	4
Steroid hormone receptor ERR1	0	1	0	1
Aromatase	0	5	0	5
Cyclin-dependent kinase 4	0	2	1	3
Ornithine decarboxylase	0	2	0	2
Proto-oncogene tyrosine-protein kinase Src	0	4	1	5
Cystic fibrosis transmembrane conductance regulator	0	0	3	3
17-beta-hydroxysteroid dehydrogenase type 1	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	2	0	2
Dipeptidyl peptidase 4	0	1	0	1
cAMP-dependent protein kinase catalytic subunit alpha	0	1	1	2
Amine oxidase [flavin-containing] A	0	1	1	2
Amine oxidase [flavin-containing] A	0	2	0	2
G1/S-specific cyclin-D1	0	2	0	2
Thromboxane-A synthase	0	1	0	1
Cruzipain	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
5-hydroxytryptamine receptor 2C	0	2	0	2
Adenosine receptor A2a	0	2	0	2
Adenosine receptor A1	0	4	0	4
Sodium-dependent serotonin transporter	0	3	0	3
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Acetylcholinesterase	0	1	0	1
Alpha-glucosidase MAL32	0	1	0	1
Signal transducer and activator of transcription 3	0	1	0	1
Tyrosine-protein kinase CSK	0	1	1	2
Tyrosine-protein kinase ABL2	0	1	1	2
Tyrosine-protein kinase SYK	0	2	2	4
Dual specificity mitogen-activated protein kinase kinase 4	0	1	1	2
Quinone oxidoreductase	0	0	0	1
Cytoplasmic tyrosine-protein kinase BMX	0	1	1	2
Mitogen-activated protein kinase 10	0	2	1	3
Oxysterols receptor LXR-beta	0	1	0	1
Amine oxidase [flavin-containing] B	0	2	0	2
Aldehyde oxidase	0	1	0	1
Oxysterols receptor LXR-alpha	0	1	0	1
Tissue alpha-L-fucosidase	0	1	0	1
Substance-K receptor	0	2	0	2
Estrogen receptor beta	0	2	1	3
Prenyltransferase homolog	0	0	0	2
Carboxylic ester hydrolase	0	1	0	1
Dipeptidyl peptidase 3	0	2	0	2
DNA (cytosine-5)-methyltransferase 3-like	0	2	0	2
Sialidase-2	0	2	0	2
DNA (cytosine-5)-methyltransferase 3A	0	2	0	2
Glycogen phosphorylase, muscle form	0	1	0	1
Asialoglycoprotein receptor 1	0	1	1	2
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Alpha-1D adrenergic receptor	0	2	0	2
Cyclic GMP-AMP synthase	0	1	0	1
Toll-like receptor 9	0	1	0	1
Toll-like receptor 7	0	1	0	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain A, Glutamate receptor 2	0	0	1	1
Chain C, Glutamate receptor 2	0	0	1	1
Glutamate receptor 1	1	3	1	5
Glutamate receptor 3	1	3	1	5
Glutamate receptor 4	1	3	1	5
Glutamate receptor ionotropic, kainate 1	0	3	1	4
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 5	0	0	1	1
Glutamate receptor ionotropic, kainate 2	0	3	2	5
Glutamate receptor 1	0	1	1	2
Glutamate receptor 2	0	1	1	2
Glutamate receptor 3	0	0	1	1
Glutamate receptor ionotropic, kainate 3	0	3	0	3
Glutamate receptor 4	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	3	0	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Glutamate receptor ionotropic, kainate 4	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate receptor ionotropic, kainate 5	0	3	0	3
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
Gap junction alpha-1 protein	0	1	0	1
Gap junction beta-2 protein	0	1	0	1
Acyl-protein thioesterase 1	0	1	0	1
Estrogen receptor	0	0	2	2
Amine oxidase [flavin-containing] B	0	1	0	1
Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial	0	1	0	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	1	0	1
Estrogen receptor beta	0	0	2	2
Renin	0	1	0	1
Type-1A angiotensin II receptor	0	1	0	1
Type-1B angiotensin II receptor	0	2	0	2
Type-2 angiotensin II receptor	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	1	0	1
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	1	0	1
5-hydroxytryptamine receptor 1A	0	1	0	1
Type-1 angiotensin II receptor	0	1	0	1
Chain A, Antigen Cd11a (p180)	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Integrin alpha-L	0	1	1	2
Substance-K receptor	0	2	0	2
Lanosterol 14-alpha demethylase	0	2	0	2
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
retinoic acid receptor alpha isoform 1	0	1	0	1
retinoic acid receptor RXR-alpha isoform a	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 2C11	0	1	0	1
Metabotropic glutamate receptor 1	0	1	0	1
Acetylcholinesterase	0	1	0	1
Mu-type opioid receptor	0	2	0	2
Nociceptin receptor	0	1	0	1
Melatonin receptor type 1C	0	0	1	1
Melatonin receptor type 1A	0	1	1	2
Melatonin receptor type 1C	0	1	1	2
Melatonin receptor type 1B	0	1	1	2
Palmitoleoyl-protein carboxylesterase NOTUM	0	1	0	1
Carboxylic ester hydrolase	0	1	0	1
Histamine H3 receptor	0	1	0	1
cystic fibrosis transmembrane conductance regulator	0	1	0	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Methionyl-tRNA synthetase	0	0	1	1
Chain A, Aminopeptidase	0	1	0	1
Chain A, Methionine aminopeptidase	0	1	0	1
S-ribosylhomocysteine lyase	0	1	0	1
Adenylate cyclase type 5	0	1	0	2
S-adenosylmethionine synthase isoform type-1	0	0	0	1
S-adenosylmethionine synthase isoform type-2	0	0	0	1
Large neutral amino acids transporter small subunit 1	0	1	0	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	1	0	1
transactivating tegument protein VP16 [Human herpesvirus 1]	0	1	0	1
nuclear receptor coactivator 3 isoform a	0	1	0	1
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	2
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
5-hydroxytryptamine receptor 2C	0	2	0	3
High mobility group protein B1	0	0	1	1
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
5-hydroxytryptamine receptor 2A	0	2	0	2
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Histidine decarboxylase	0	1	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Cyclin-dependent kinase 2	0	1	2	3
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Multidrug resistance-associated protein 1	0	1	0	2
Delta-type opioid receptor	0	1	0	1
Kappa-type opioid receptor	0	1	0	1
Reduced folate transporter	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Solute carrier family 22 member 6	0	0	0	1
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Solute carrier family 22 member 11	0	0	0	1
Protein-arginine deiminase type-4	0	2	0	2
Glycine receptor subunit alpha-1	0	2	0	2
Glycine receptor subunit beta	0	2	0	2
Glycine receptor subunit alpha-2	0	2	0	2
Glycine receptor subunit alpha-3	0	2	0	2
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain A, NAD-dependent deacetylase	0	1	0	1
Poly [ADP-ribose] polymerase 2	0	1	0	1
NAD-dependent histone deacetylase SIR2	0	1	0	1
Coagulation factor VII	0	1	0	1
Poly [ADP-ribose] polymerase 1	0	1	0	1
Cytochrome P450 3A5	0	2	0	2
NAD-dependent protein deacetylase HST2	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
Protein mono-ADP-ribosyltransferase PARP15	0	1	0	1
NAD-dependent protein deacetylase sirtuin-2	0	1	1	2
NAD-dependent protein deacetylase sirtuin-6	0	1	0	1
NAD-dependent protein deacetylase sirtuin-1	0	1	1	4
NAD-dependent protein deacetylase sirtuin-3, mitochondrial	0	1	1	2
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	1	0	1
NAD-dependent protein deacetylase	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-4	0	1	0	1
Voltage-dependent P/Q-type calcium channel subunit alpha-1A	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1G	0	1	0	1
Voltage-dependent calcium channel gamma-3 subunit	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1H	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-3	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Voltage-dependent calcium channel gamma-7 subunit	0	1	0	1
Voltage-dependent N-type calcium channel subunit alpha-1B	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-1	0	1	0	1
Voltage-dependent calcium channel gamma-1 subunit	0	1	0	1
Voltage-dependent L-type calcium channel subunit beta-2	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Voltage-dependent R-type calcium channel subunit alpha-1E	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-4	0	1	0	1
Transient receptor potential cation channel subfamily A member 1	0	0	1	1
Voltage-dependent calcium channel subunit alpha-2/delta-3	0	1	0	1
Voltage-dependent calcium channel gamma-8 subunit	0	1	0	1
Bile acid receptor	0	1	1	2
Voltage-dependent calcium channel gamma-6 subunit	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-2	0	1	0	1
Voltage-dependent T-type calcium channel subunit alpha-1I	0	1	0	1
Voltage-dependent calcium channel gamma-4 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-5 subunit	0	1	0	1
Voltage-dependent calcium channel gamma-2 subunit	0	1	0	1
interferon gamma precursor	0	0	0	2
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
Neuronal acetylcholine receptor subunit alpha-4	0	2	0	2
Breakpoint cluster region protein	0	4	1	7
Neuronal acetylcholine receptor subunit beta-2	0	2	0	2
5-hydroxytryptamine receptor 1A	0	2	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	0	0	2
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain B, (3R)-hydroxymyristoyl-acyl carrier protein dehydratase	0	1	0	1
Chain A, APH(2')-Id	0	1	0	1
glucose-6-phosphate dehydrogenase	0	1	0	1
signal transducer and activator of transcription 6, interleukin-4 induced	1	0	0	1
NUAK family SNF1-like kinase 1	0	1	1	2
B2 bradykinin receptor	0	1	0	1
G2/mitotic-specific cyclin-B2	0	1	0	1
Prothrombin	0	1	0	1
Cationic trypsin	0	1	0	1
Chymotrypsinogen A	0	1	0	1
Chymotrypsin-like elastase family member 1	0	1	0	1
Beta-lactamase	0	1	0	1
Protein E6	0	1	0	1
Interstitial collagenase	0	1	1	2
Beta-lactamase	0	1	0	1
Tyrosine-protein kinase Lck	0	4	1	5
Glycogen phosphorylase, liver form	0	1	1	2
Epoxide hydrolase 1	0	1	0	1
Tyrosine-protein kinase Yes	0	1	1	2
Proto-oncogene tyrosine-protein kinase receptor Ret	0	1	1	2
Insulin-like growth factor 1 receptor	0	1	1	2
Stromelysin-1	0	2	0	2
Heterogeneous nuclear ribonucleoprotein A1	0	0	1	1
Calmodulin-1	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Malate dehydrogenase	0	1	0	1
Cytochrome P450 2C8	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 2	0	1	0	1
Serine/threonine-protein kinase pim-1	0	1	2	3
Polyunsaturated fatty acid 5-lipoxygenase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Serine/threonine-protein kinase B-raf	0	1	1	2
G2/mitotic-specific cyclin-B	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Aldo-keto reductase family 1 member B1	0	1	0	1
Chymotrypsinogen B	0	1	0	1
Polyunsaturated fatty acid lipoxygenase ALOX12	0	1	0	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Casein kinase II subunit alpha'	0	2	1	3
5'-nucleotidase	0	1	0	1
Glyceraldehyde-3-phosphate dehydrogenase, glycosomal	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
C-X-C chemokine receptor type 1	0	2	0	2
Phosphatidylinositol 3-kinase regulatory subunit alpha	0	1	0	1
Cytosol aminopeptidase	0	1	0	1
ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1	0	2	0	2
Vasopressin V2 receptor	0	1	0	1
Tyrosine-protein kinase receptor UFO	0	1	1	2
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	1
Receptor-type tyrosine-protein kinase FLT3	0	3	1	4
Macrophage metalloelastase	0	2	0	2
Glutathione reductase	0	1	0	1
Collagenase 3	0	2	0	2
1-deoxy-D-xylulose 5-phosphate reductoisomerase	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
Glycogen synthase kinase-3 alpha	0	1	1	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Serine/threonine-protein kinase Nek2	0	1	1	2
Oligo-1,6-glucosidase IMA1	0	1	0	1
Monocarboxylate transporter 1	0	1	0	1
Anthrax toxin receptor 2	0	1	0	1
Casein kinase II subunit beta	0	2	0	2
Casein kinase II subunit alpha	0	2	1	3
Aldo-keto reductase family 1 member B1	0	1	0	1
Cyclin-dependent kinase 6	0	1	1	2
Cyclin-dependent-like kinase 5	0	1	1	2
Heat shock factor protein 1	0	1	0	1
Sorbitol dehydrogenase	0	1	0	1
Cyclin homolog	0	1	0	1
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Focal adhesion kinase 1	0	1	1	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	1	1	2
ELAV-like protein 3	0	1	0	1
Cyclin-dependent kinase 5 activator 1	0	1	0	1
ELAV-like protein 1	0	1	0	1
Serine/threonine-protein kinase N1	0	1	1	2
Probable maltase-glucoamylase 2	0	1	0	1
Monocarboxylate transporter 2	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Casein kinase II subunit alpha 3	0	2	0	2
Inositol polyphosphate multikinase	0	1	0	1
G2/mitotic-specific cyclin-B3	0	1	0	1
Aldo-keto reductase family 1 member C21	0	2	0	2
Chymotrypsin-C	0	1	0	1
Cyclin-dependent kinase 1	0	1	0	1
Phosphodiesterase	0	1	0	1
Serine/threonine-protein kinase Nek6	0	1	1	2
NADPH oxidase 4	0	1	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	1	0	1
Inositol hexakisphosphate kinase 2	0	1	0	1
Short transient receptor potential channel 5	0	1	0	1
ALK tyrosine kinase receptor	0	1	1	2
Solute carrier family 22 member 1	0	1	0	1
Solute carrier organic anion transporter family member 1A4	0	2	0	3
Solute carrier family 22 member 2	0	1	0	1
Potassium channel subfamily K member 2	0	1	0	1
Cytochrome P450 2D1	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Solute carrier organic anion transporter family member 1A1	0	2	0	3
Cytochrome P450 2D4	0	1	0	1
Chain A, Troponin C, slow skeletal and cardiac muscles	0	0	1	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
Chain A, Leukotriene A-4 hydrolase	0	1	0	1
M18 aspartyl aminopeptidase	0	1	0	1
cathepsin L1	0	1	0	1
Vif	0	2	0	2
transcription factor p65 isoform 1	0	0	1	1
serine/threonine-protein kinase 33 isoform a	0	0	1	1
Aryl hydrocarbon receptor	0	1	0	1
Estrogen receptor beta	0	0	1	1
Myc proto-oncogene protein	0	1	0	2
Cathepsin D	0	1	0	1
Luciferin 4-monooxygenase	0	1	0	1
DNA polymerase alpha catalytic subunit	0	1	0	1
Leukotriene A-4 hydrolase	0	1	0	1
Estrogen receptor	0	0	1	1
Cannabinoid receptor 1	0	1	0	1
D(1A) dopamine receptor	1	1	0	2
Squalene synthase	0	1	0	1
N1L	0	1	0	1
NAD(P)H dehydrogenase [quinone] 1	0	0	0	3
Tubulin beta-2B chain	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
Carbonic anhydrase 13	0	1	0	1
DNA (cytosine-5)-methyltransferase 3B	0	1	0	1
Chain A, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain B, 6,7-Dimethyl-8-ribityllumazine Synthase	0	0	1	1
Chain H, Immunoglobulin Igg1 Heavy chain	0	0	1	1
Chain L, Immunoglobulin Igg1 Lambda Light Chain	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain A, DODECIN	0	0	1	1
Chain C, DODECIN	0	0	1	1
Chain E, DODECIN	0	0	1	1
NPYLR7B	0	0	1	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
NH(3)-dependent NAD(+) synthetase	0	1	0	1
Cytochrome P450 2B6	0	0	1	1
Arylacetamide deacetylase	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	1	0	1
Glutathione S-transferase omega-1	0	1	0	1
DNA-directed RNA polymerase subunit beta	0	1	0	1
Leukotriene C4 synthase	0	0	1	1
Bone morphogenetic protein receptor type-1B	0	0	1	1
Membrane-associated progesterone receptor component 1	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase PLK4	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
ATP-dependent RNA helicase DDX3X	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Pyridoxal kinase	0	0	1	1
Citron Rho-interacting kinase	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Serine/threonine-protein kinase Chk1	0	0	1	1
Peripheral plasma membrane protein CASK	0	0	1	1
Aurora kinase A	0	0	1	1
Cyclin-G-associated kinase	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
Ephrin type-B receptor 6	0	0	1	1
Peroxisomal acyl-coenzyme A oxidase 3	0	0	1	1
Mitogen-activated protein kinase 13	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 2	0	0	1	1
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	1	1
Dynamin-like 120 kDa protein, mitochondrial	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Tyrosine-protein kinase JAK2	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	1	1
Rho-associated protein kinase 2	0	0	1	1
Serine/threonine-protein kinase ULK1	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	1	1
Ribosomal protein S6 kinase alpha-5	0	0	1	1
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	1	1
Ribosomal protein S6 kinase alpha-4	0	0	1	1
Serine/threonine-protein kinase 16	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	1	1
Serine/threonine-protein kinase 17B	0	0	1	1
Serine/threonine-protein kinase 10	0	0	1	1
Serine/threonine-protein kinase D3	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Structural maintenance of chromosomes protein 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 6	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	1	1
Serine/threonine-protein kinase LATS1	0	0	1	1
Serine/threonine-protein kinase PAK 4	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
Low-density lipoprotein receptor	0	1	0	1
Fibronectin	0	1	0	1
Receptor tyrosine-protein kinase erbB-2	0	0	1	1
High affinity nerve growth factor receptor	0	0	1	1
ADP/ATP translocase 2	0	0	1	1
Protein kinase C beta type	0	0	1	1
Insulin receptor	0	0	1	1
Tyrosine-protein kinase Fes/Fps	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Tyrosine-protein kinase Lyn	0	1	1	2
Signal recognition particle receptor subunit alpha	0	0	1	1
Cytochrome c1, heme protein, mitochondrial	0	0	1	1
Tyrosine-protein kinase HCK	0	1	1	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Platelet-derived growth factor receptor beta	0	1	1	2
Tyrosine-protein kinase Fgr	0	0	1	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Serine/threonine-protein kinase A-Raf	0	0	1	1
Mast/stem cell growth factor receptor Kit	0	2	1	3
Glycogen phosphorylase, brain form	0	0	1	1
Fibroblast growth factor receptor 1	0	0	1	1
ADP/ATP translocase 3	0	0	1	1
Inosine-5'-monophosphate dehydrogenase 2	0	0	1	1
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	1	1
Insulin receptor-related protein	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	1	1
Platelet-derived growth factor receptor alpha	0	1	1	2
Tyrosine-protein kinase Fer	0	0	1	1
Vascular endothelial growth factor receptor 1	0	0	1	1
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Ras-related protein Rab-6A	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Ephrin type-A receptor 1	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Multifunctional protein ADE2	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	1	1
cAMP-dependent protein kinase catalytic subunit beta	0	0	1	1
Ferrochelatase, mitochondrial	0	0	1	1
Tyrosine-protein kinase JAK1	0	0	1	1
Protein kinase C eta type	0	0	1	1
Beta-adrenergic receptor kinase 1	0	0	1	1
Probable ATP-dependent RNA helicase DDX6	0	0	1	1
Activin receptor type-2A	0	0	1	1
MAP/microtubule affinity-regulating kinase 3	0	0	1	1
Deoxycytidine kinase	0	0	1	1
Ephrin type-A receptor 2	0	1	1	2
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Ephrin type-B receptor 2	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Non-receptor tyrosine-protein kinase TYK2	0	0	1	1
UMP-CMP kinase	0	0	1	1
Phosphatidylethanolamine-binding protein 1	0	0	1	1
Wee1-like protein kinase	0	0	1	1
Heme oxygenase 2	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
S-adenosylmethionine synthase isoform type-2	0	0	1	1
DnaJ homolog subfamily A member 1	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	1	1
DNA replication licensing factor MCM4	0	0	1	1
Myosin-10	0	0	1	1
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 2	0	0	1	1
Bone morphogenetic protein receptor type-1A	0	0	1	1
Activin receptor type-1B	0	0	1	1
TGF-beta receptor type-1	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	1	1
TGF-beta receptor type-2	0	0	1	1
Glycine--tRNA ligase	0	0	1	1
Protein kinase C iota type	0	0	1	1
Exosome RNA helicase MTR4	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase Tec	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase FRK	0	0	1	1
G protein-coupled receptor kinase 6	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
26S proteasome regulatory subunit 6B	0	0	1	1
Mitogen-activated protein kinase 8	0	0	1	1
Mitogen-activated protein kinase 9	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 3	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	1	1
Casein kinase I isoform alpha	0	0	1	1
Casein kinase I isoform delta	0	0	1	1
Cyclin-dependent kinase 8	0	0	1	1
Elongation factor Tu, mitochondrial	0	0	1	1
Cysteine--tRNA ligase, cytoplasmic	0	0	1	1
Casein kinase I isoform epsilon	0	0	1	1
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	1	1
Dual specificity protein kinase CLK1	0	0	1	1
Dual specificity protein kinase CLK2	0	0	1	1
Dual specificity protein kinase CLK3	0	0	1	1
Cyclin-dependent kinase 7	0	0	1	1
Cyclin-dependent kinase 9	0	0	1	1
Ras-related protein Rab-27A	0	0	1	1
Tyrosine-protein kinase Blk	0	1	1	2
Interleukin-1 receptor-associated kinase 1	0	0	1	1
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Ribosomal protein S6 kinase alpha-3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek3	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 6	0	0	1	1
LIM domain kinase 1	0	0	1	1
LIM domain kinase 2	0	0	1	1
Mitogen-activated protein kinase 12	0	0	1	1
Tyrosine--tRNA ligase, cytoplasmic	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	1
Ephrin type-B receptor 3	0	0	1	1
Ephrin type-A receptor 5	0	0	1	1
Ephrin type-B receptor 4	0	0	1	1
Ephrin type-B receptor 1	0	0	1	1
Ephrin type-A receptor 4	0	0	1	1
Adenylate kinase 2, mitochondrial	0	0	1	1
Adenosine kinase	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Ras-related protein Rab-10	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Actin-related protein 3	0	0	1	1
Actin-related protein 2	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
GTP-binding nuclear protein Ran	0	0	1	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase 3	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Cyclin-dependent kinase 16	0	0	1	1
Cyclin-dependent kinase 17	0	0	1	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	1	1
Protein kinase C epsilon type	0	0	1	1
Angiopoietin-1 receptor	0	0	1	1
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
DNA topoisomerase 2-beta	0	0	1	1
Protein kinase C theta type	0	0	1	1
Activin receptor type-1	0	0	1	1
Macrophage-stimulating protein receptor	0	0	1	1
Protein kinase C zeta type	0	0	1	1
Protein kinase C delta type	0	0	1	1
Tyrosine-protein kinase BTK	0	0	1	1
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	1	1
Activated CDC42 kinase 1	0	0	1	1
Epithelial discoidin domain-containing receptor 1	0	2	1	3
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Tyrosine-protein kinase Mer	0	0	1	1
Serine/threonine-protein kinase 4	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 5	0	0	1	1
Mitogen-activated protein kinase 7	0	0	1	1
Serine/threonine-protein kinase PAK 2	0	0	1	1
Serine/threonine-protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Integrin-linked protein kinase	0	0	1	1
Rho-associated protein kinase 1	0	0	1	1
Non-receptor tyrosine-protein kinase TNK1	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	1	1
Activin receptor type-2B	0	0	1	1
Bone morphogenetic protein receptor type-2	0	0	1	1
Protein-tyrosine kinase 6	0	0	1	1
cGMP-dependent protein kinase 1	0	0	1	1
Cyclin-dependent kinase 13	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	1	1
Protein-tyrosine kinase 2-beta	0	0	1	1
Maternal embryonic leucine zipper kinase	0	0	1	1
Structural maintenance of chromosomes protein 1A	0	0	1	1
Chromodomain-helicase-DNA-binding protein 4	0	0	1	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	1	1
Delta(24)-sterol reductase	0	0	1	1
Ribosomal protein S6 kinase alpha-1	0	0	1	1
Dual specificity testis-specific protein kinase 1	0	0	1	1
Myosin light chain kinase, smooth muscle	0	0	1	1
Mitogen-activated protein kinase 11	0	0	1	1
Serine/threonine-protein kinase STK11	0	0	1	1
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
Serine/threonine-protein kinase N2	0	0	1	1
Calcium/calmodulin-dependent protein kinase type IV	0	0	1	1
Mitogen-activated protein kinase kinase kinase 11	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Discoidin domain-containing receptor 2	0	2	1	3
AP2-associated protein kinase 1	0	0	1	1
Myosin light chain kinase 3	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Putative heat shock protein HSP 90-beta 2	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Rab-like protein 3	0	0	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase MRCK alpha	0	0	1	1
Serine/threonine-protein kinase MRCK gamma	0	0	1	1
Acyl-CoA dehydrogenase family member 10	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Serine/threonine-protein kinase N3	0	0	1	1
Serine/threonine-protein kinase ULK3	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
Uncharacterized protein FLJ45252	0	0	1	1
Acyl-CoA dehydrogenase family member 11	0	0	1	1
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	1	1
Serine/threonine-protein kinase MARK2	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	1	1
Serine/threonine-protein kinase TAO1	0	0	1	1
STE20-related kinase adapter protein alpha	0	0	1	1
Myosin-14	0	0	1	1
AarF domain-containing protein kinase 1	0	0	1	1
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Multidrug resistance-associated protein 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	1	1
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Proprotein convertase subtilisin/kexin type 9	0	1	0	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Atypical kinase COQ8A, mitochondrial	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	1	1
Mitogen-activated protein kinase 15	0	0	1	1
Serine/threonine-protein kinase Nek9	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Serine/threonine-protein kinase Nek7	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
ATP-dependent RNA helicase DDX1	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
MAP/microtubule affinity-regulating kinase 4	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	1	1
EKC/KEOPS complex subunit TP53RK	0	0	1	1
Dual specificity testis-specific protein kinase 2	0	0	1	1
SRSF protein kinase 1	0	0	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 5	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Mitogen-activated protein kinase kinase kinase 3	0	0	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Nucleolar GTP-binding protein 1	0	0	1	1
Serine/threonine-protein kinase D2	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
NUAK family SNF1-like kinase 2	0	0	1	1
RNA cytidine acetyltransferase	0	0	1	1
Serine/threonine-protein kinase SIK2	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
STE20-like serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase TAO3	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
dCTP pyrophosphatase 1	0	0	1	1
Dual specificity protein kinase CLK4	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Casein kinase I isoform gamma-1	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	1	1
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Phenylalanine--tRNA ligase beta subunit	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	1	1
BMP-2-inducible protein kinase	0	0	1	1
Obg-like ATPase 1	0	0	1	1
Midasin	0	0	1	1
Interleukin-1 receptor-associated kinase 4	0	0	1	1
Serine/threonine-protein kinase 32B	0	0	1	1
Mitogen-activated protein kinase kinase kinase 20	0	0	1	1
Cyclin-dependent kinase 12	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase pim-2	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
Serine/threonine-protein kinase 26	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	1	1
Serine/threonine-protein kinase NLK	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
5'-AMP-activated protein kinase subunit gamma-2	0	0	1	1
Serine/threonine-protein kinase TBK1	0	0	1	1
Septin-9	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Ribosomal protein S6 kinase alpha-6	0	0	1	1
TRAF2 and NCK-interacting protein kinase	0	0	1	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
Serine/threonine-protein kinase TAO2	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
RAC-gamma serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase 38-like	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase SIK3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 2	0	0	1	1
Thyroid hormone receptor-associated protein 3	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 3	0	0	1	1
Serine/threonine-protein kinase MRCK beta	0	0	1	1
Interleukin-1 receptor-associated kinase 3	0	0	1	1
Serine/threonine-protein kinase 24	0	0	1	1
Casein kinase I isoform gamma-3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 4	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Kinesin-like protein KIF11	0	2	1	3
Adenylate cyclase type 6	0	1	0	1
Adenylate cyclase type 3	0	1	0	1
Adenylate cyclase type 9	0	1	0	1
D	0	4	0	6
D(3) dopamine receptor	0	1	0	1
D(1B) dopamine receptor	0	3	0	3
5-hydroxytryptamine receptor 2B	0	1	0	1
D(1) dopamine receptor	0	1	0	1
Adenylate cyclase type 7	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	0	1
Adenylate cyclase type 2	0	1	0	1
D	0	1	0	1
Adenylate cyclase type 4	0	1	0	1
D	0	1	0	1
UDP-glucuronosyltransferase 2B7	0	0	0	1
UDP-glucuronosyltransferase 1A4	0	0	0	1
Peptidyl-prolyl cis-trans isomerase FKBP1A	0	2	1	3
Peptidyl-prolyl cis-trans isomerase FKBP1B	0	0	1	1
Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform	0	1	0	1
Splicing factor 3B subunit 3	0	1	0	1
RAD51	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Tyrosine-protein phosphatase non-receptor type 6	0	1	0	1
Tyrosine-protein phosphatase non-receptor type 11	0	1	0	1
Polycomb protein SUZ12	0	1	0	1
Histone-lysine N-methyltransferase EZH2	0	1	0	1
Hypoxia-inducible factor 1-alpha	0	1	0	1
Endothelial PAS domain-containing protein 1	0	1	0	1
Protease	0	1	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	1
Sodium/bile acid cotransporter	0	0	0	1
Ileal sodium/bile acid cotransporter	0	1	0	1
G-protein coupled bile acid receptor 1	0	0	1	1
Bile salt export pump	0	0	0	1
ATP-dependent translocase ABCB1	0	0	1	1
eyes absent homolog 2 isoform a	1	0	0	1
Angiotensin-converting enzyme	0	1	0	1
Thromboxane A2 receptor	0	0	0	1
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Glycine receptor subunit alpha-1	0	0	1	1
Type-1 angiotensin II receptor	0	1	0	2
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	1	1	2
Peroxisome proliferator-activated receptor gamma	0	0	1	1
Type-2 angiotensin II receptor	0	1	0	1
Peroxisome proliferator-activated receptor delta	0	1	1	2
Peroxisome proliferator-activated receptor alpha	0	1	1	2
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
1-deoxy-D-xylulose-5-phosphate synthase	0	0	1	1
Ubiquitin-like modifier activating enzyme 2	0	1	0	1
SUMO1 activating enzyme subunit 1	0	1	0	1
SUMO-conjugating enzyme UBC9	0	1	0	1
Tat	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with trehalose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with cellobiose	0	1	0	1
Chain A, X-ray structure of the sucrose-phosphatase (SPP) from Synechocystis sp.PCC6803 in complex with maltose	0	1	0	1
Trehalose-phosphatase	0	1	0	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Retinoic acid receptor alpha	0	2	2	7
Retinoic acid receptor beta	0	2	2	7
Retinoic acid receptor alpha	0	1	2	3
Retinoic acid receptor gamma	0	2	2	7
Alpha-1A adrenergic receptor	0	1	0	1
Retinoic acid receptor gamma	0	1	2	3
Retinoic acid receptor RXR-alpha	0	2	2	4
Retinoic acid receptor beta	0	1	2	3
Cellular retinoic acid-binding protein 2	0	0	1	1
Retinoic acid receptor RXR-alpha	0	1	2	3
Retinoic acid receptor RXR-beta	0	2	2	4
Retinoic acid receptor RXR-beta	0	1	2	3
Retinoic acid receptor RXR-gamma	0	1	2	3
Indoleamine 2,3-dioxygenase 1	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Cellular retinoic acid-binding protein 1	0	1	0	2
Retinoic acid receptor RXR-gamma	0	2	2	4
Cellular retinoic acid-binding protein 1	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	1	0	1
Nuclear receptor ROR-beta	0	1	0	1
Olfactory receptor 51E2	0	0	1	1
D-alanyl-D-alanine dipeptidase	0	1	0	1
Transporter	0	1	0	1
twin arginine protein translocation system - TatA protein	0	0	0	1
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Drug-Induced Cochlear Toxicity

Synonyms(10)

Research

Studies (265)

Protein Targets (1,812)

Drug-Induced Cochlear Toxicity

Synonyms(10)

Research

Studies (265)

Drugs Studied (166)

Protein Targets (1,812)