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oxetanes

Any oxacycle that is oxetane or its substituted derivatives.

ChEBI ID: 38784

Members (4)

MemberDefinitionRole
AZD1979A carboxamide resulting from the formal condensation of the carboxy group of 5-(p-methoxyphenyl)-1,3,4-oxadiazole-2-carboxylic acid with the amino group of 3-phenoxyazetidine and in which the phenoxy group has been substituted at the para- position by a 2-oxa-6-azaspiro[3.3]heptan-6-ylmethyl group. It is a melanin concentrating hormone receptor 1 (MCHr1) antagonist.AZD1979
crenolanibA member of the class of benzimidazoles that is 1H-benzimidazole which is substituted by a 8-(4-aminopiperidin-1-yl)quinolin-2-yl group at position 1 and by a (3-methyloxetan-3-yl)methoxy group at position 5. It is an inhibitor of type III tyrosine kinases, PDGFRalpha/beta and FLT3 (IC50 of 11, 3.2, and 4 nM). Currently under clinical development for the treatment of acute myeloid leukemia.crenolanib
oxetaneA saturated organic heteromonocyclic parent that is a four-membered ring comprising of three carbon atoms and an oxygen atom.oxetane
oxetanocin aA nucleoside analogue found in Bacillus megaterium in which an adenine moiety is attached to position 2 of a of an oxetane ring which is substituted at positions 3 and 4 by hydroxymethyl groups.oxetanocin A

Research

Studies (274)

TimeframeStudies, Drugs in This Class (%)All Drugs %
pre-199010 (3.65)18.7374
1990's20 (7.30)18.2507
2000's65 (23.72)29.6817
2010's136 (49.64)24.3611
2020's43 (15.69)2.80

Study Types

Publication TypeStudies, Drugs in This Class (%)All Drugs (%)
Trials4 (1.45%)5.53%
Reviews20 (7.27%)6.00%
Case Studies0 (0.00%)4.05%
Observational0 (0.00%)0.25%
Other251 (91.27%)84.16%