Xanthoma

A condition marked by the development of widespread xanthomas, yellow tumor-like structures filled with lipid deposits. Xanthomas can be found in a variety of tissues including the SKIN; TENDONS; joints of KNEES and ELBOWS. Xanthomatosis is associated with disturbance of LIPID METABOLISM and formation of FOAM CELLS.

Synonym
Xanthomatosis
Xanthoma

Excerpt	Reference
"Since xanthomas are usually not diagnostic of a specific disease entity, history, physical, and laboratory data are required for appropriate classification and treatment."	( Dubin, HV; Love, JR, 1978)
"Cerebrotendinous xanthomatosis is a familial recessive disorder."	( Berginer, VM; Foster, NL; Sadowsky, M; Salen, G; Siegel, GJ; Townsend, JA, 1988)
"Cerebrotendinous xanthomatosis is a recessively inherited disorder of bile acid metabolism."	( White, SW, 1985)
"Cerebrotendinous Xanthomatosis is a rare, inherited disease characterized by an extraordinary accumulation of cholestanol in all tissues, xanthomatous deposits in the brain, lungs, and Achilles tendons, premature atherosclerosis, and low plasma cholesterol concentrations."	( Polito, A; Salen, G, 1972)
"Cerebrotendinous xanthomatosis is an unusual disease, clinically characterized by dementia, cataracts, progressive cerebellar ataxia, pyramidal signs, and multiple xanthomas of tendons and other tissues."	( Brotto, MW; Canelas, HM; Quintão, EC; Scaff, M; Vasconcelos, KS, 1983)
"Cerebrotendinous xanthomatosis is a rare, inherited disease characterized by defective bile acid biosynthesis as well as by accumulation of cholesterol and cholestanol."	( Björkhem, I; Buchmann, MS; Skrede, S, 1983)
"Cerebrotendinous xanthomatosis is a genetically transmitted disease that is associated with deposition of cholestanol in the central nervous system and Achilles tendons."	( Shapiro, S, 1983)
"Xanthomas are classified into 5 subtypes: xanthelasma, planar xanthoma, papulo-eruptive xanthoma, tuberous xanthoma and tendon xanthoma."	( Hata, Y; Hirose, N; Oikawa, T; Shigematsu, H; Tsushima, M; Yamamoto, M; Yamauchi, Y, 1981)
"Verruciform xanthoma is a rare clinicopathologic entity of uncertain etiology that occurs primarily in the oral mucosa."	( Amin, MB; Eyzaguirre, E; Lee, MW; Ma, CK; Mohsin, SK; Stoler, MH; Zarbo, RJ, 1998)
"Xanthomas are cutaneous lesions due to a local accumulation of spumous cells in the dermal tissue or the tendons."	( de la Brassinne, M; de Schaetzen, V; Richert, B, 2004)
"Verruciform xanthoma is most likely not a human papillomavirus associated lesion and the foam cells like that, are most likely derived from monocyte-macrophage lineage."	( Hu, JA; Li, SY; Li, YN; Ying, H, 2005)
"Xanthomas are a common presentation of disorders of lipid metabolism, usually associated with abnormalities of cholesterol metabolism."	( Singla, A, 2006)
"Verruciform xanthoma is xanthomatous dermal infiltrate in a proliferating epidermal lesion and is an uncommon phenomenon."	( Hsiao, PF; Lin, YC; Wu, YH, 2006)
"Cutaneous eruptive xanthomas are characteristics lesions of hyperlipidemia."	( Aldabagh, B; Bergfeld, W, 2010)
"Eruptive xanthomatosis is a papular skin disorder resulting from hyperlipidemia, specifically hypertriglyceridemia."	( Farber, G; Mosadegh, M; Pickens, S, 2012)
"Primary bone xanthoma is an extremely rare benign bone tumor histologically characterized by mononuclear macrophage-like cells, abundant foam cells, and multinucleated giant cells."	( Benech, R; Berrone, S; Boffano, P; Campisi, P; Gallesio, C; Roccia, F, 2013)
"Hepatic xanthoma is an extremely rare lesion worldwide."	( Chao, TK; Huang, HH; Meng, FC, 2013)
"Verruciform xanthoma is a benign verrucous lesion characterized by epithelial acanthosis and lipid-laden foamy histiocytes in the connective tissue papillae."	( Beutler, BD; Cohen, PR, 2015)
" Verruciform xanthoma is a benign tumor commonly located within the oral cavity and characterized by the development of a small verrucous, papillomatous, polypoid, or sessile growth."	( Beutler, BD; Cohen, PR, 2015)
"Atypical Fibroxanthoma is an unusual dermal mesenchymal tumor."	( Jara, N; Solé Z, S, 2019)
"Xanthomas are subcutaneous lipid deposits containing macrophages loaded with cholesterol and cholesterol esters."	( Bhattarai, S; Khadka, A, 2020)

Excerpt	Reference
"Tuboeruptive xanthomata, palmar xanthoma, and xanthoma striata palmare subsided with treatment."	( Dodge, HT; Kostis, JB; Kuo, PT; Moreyra, AB; Wilson, AC, 1988)
"We describe a florid xanthomatous histiocytic reaction in the pelvic lymph nodes of a patient treated with androgen deprivation therapy prior to radical prostatectomy."	( Gormley, EA; Schned, AR, 1996)
"The incidence and severity of xanthomata in the digital joints were also decreased significantly in the three treated groups."	( Horikoshi, H; Ito, T; Shiomi, M; Tsujita, Y; Tsukada, T, 1999)
"In contrast, Achilles' tendon xanthoma regressed in four of five patients (80%) treated with pravastatin, but only in two of five patients (40%) treated with probucol."	( Chichibu, K; Inazu, A; Kajinami, K; Kiyohar, T; Koizumi, J; Mabuchi, H, 1999)
"VasoCare therapy also reduced the xanthoma formation and limb swelling characteristic of this animal model."	( Babaei, S; Monge, JC; Picard, P; Stewart, DJ, 2002)
"HDMEC were incubated with xanthoma tissue-modified LDL (x-LDL), a model of extravasated LDL oxidized in xanthoma lesions, or Cu(2+)-treated LDL (Cu-LDL), a model of oxidized LDL."	( Ikeda, M; Kodama, H; Matsumoto, M; Seike, M, 2003)
"A 19-month-old girl with cutaneous xanthomas was diagnosed with homozygous familial hypercholesterolaemia, treated with atorvastatin, plasma exchange and finally at the age of 3."	( Moyle, M; Tate, B, 2004)
"Cerebrotendinous Xanthomatosis (CTX) is a treatable inborn error of metabolism caused by recessive variants in CYP27A1."	( Appadurai, V; Bonnen, PE; Chiang, PW; DeBarber, A; Patel, SB; Steiner, RD; Tyler, C, 2015)
"Secondary xanthoma-like changes after radiation therapy or chemotherapy have been rarely reported in association with large-cell T-cell anaplastic lymphoma."	( Carrillo-Guijón, R; Hermosa-Zarza, E; Jaén-Olasolo, P; Perez-Gala, S; Turrión-Merino, L; Urech-García-de-la-Vega, M, 2016)
"With this treatment, pre-existing xanthomata can regress and coronary artery disease can be prevented."	( Shu, KH; Tsai, JL; Tsai, SF; Wu, MJ, 2016)
"Most patients with diffuse plane xanthomas present elevated blood lipid levels, and they benefit from treatment with oral lipid-lowering agents."	( Gu, Y; Lu, Y; Tan, Y; Wang, X; Yao, Z; Yu, X; Zha, S, 2022)

Timeframe	Studies, This Condition (%)	All Conditions %
pre-1990	751 (62.22)	23.3326
1990's	145 (12.01)	12.5806
2000's	129 (10.69)	18.1394
2010's	137 (11.35)	28.8240
2020's	45 (3.73)	9.53

Drug	Relationship Strength	Studies	Trials
acetoacetic acid	low	1	0
acetic acid	low	2	0
adenine	low	1	0
beta-alanine	low	1	0
bromide	low	1	0
choline	low	1	0
salicylic acid	low	18	0
3-hydroxybutyric acid	low	1	0
cytosine	low	1	0
lactic acid	low	1	0
dimethyl sulfoxide	low	1	0
glycerol	low	2	0
histamine	low	2	0
iodine	low	1	0
methanol	medium	2	1
inositol	low	2	0
nickel	low	1	0
niacin	low	8	0
nitrates	low	2	0
nitrous oxide	low	1	0
palmitic acid	low	1	0
pyruvic acid	low	1	0
uric acid	low	19	0
urea	low	1	0
1-anilino-8-naphthalenesulfonate	low	30	0
phenytoin	low	1	0
acetohexamide	low	1	0
theophylline	low	1	0
aspirin	low	1	0
azathioprine	low	1	0
bupivacaine	low	1	0
camphor, (+-)-isomer	low	1	0
chlorambucil	low	6	0
chlorpromazine	low	4	0
chlorpropamide	low	2	0
clofibrate	medium	43	2
clofibric acid	low	1	0
dapsone	low	2	0
diazoxide	low	1	0
pentetic acid	low	1	0
diphenhydramine	low	1	0
diphenylpyraline	low	1	0
valproic acid	low	1	0
doxepin	low	1	0
ether	low	1	0
fenofibrate	low	3	0
flutamide	low	1	0
gemfibrozil	low	4	0
glutethimide	low	1	0
haloperidol	low	1	0
hydroxyurea	low	1	0
indomethacin	low	2	0
iomeprol	low	1	0
isoniazid	low	1	0
2-propanol	low	8	0
khellin	low	6	0
kojic acid	low	1	0
losartan	low	1	0
metformin	low	2	0
miconazole	low	1	0
apnea	low	1	0
pantoprazole	low	1	0
phenobarbital	low	2	0
pirenzepine	low	1	0
pramoxine	low	1	0
probucol	medium	24	5
procainamide	low	1	0
propranolol	low	1	0
pyridinolcarbamate	low	1	0
resorcinol	low	1	0
thalidomide	low	1	0
tolbutamide	low	2	0
tolnaftate	low	1	0
troglitazone	low	1	0
mitomycin	low	1	0
prednisolone	low	13	0
thymidine	low	1	0
hydroxyproline	low	1	0
thyroxine	low	9	0
penicillamine	low	1	0
norethandrolone	low	1	0
prednisone	low	16	0
oxandrolone	medium	1	1
androsterone	low	6	0
triiodothyronine	low	2	0
biguanides	low	1	0
aspartic acid	low	1	0
sucrose	low	1	0
ethinyl estradiol	low	1	0
methyltestosterone	low	1	0
dromostanolone	low	1	0
levodopa	low	1	0
p-dimethylaminoazobenzene	low	1	0
phenylethyl alcohol	low	1	0
methylene blue	low	3	0
leucine	low	1	0
phenylalanine	low	1	0
desoxycorticosterone	low	2	0
colchicine	low	2	0
norethindrone	low	2	0
cytarabine	low	1	0
histidine	low	1	0
valine	low	2	0
methandrostenolone	low	1	0
tryptophan	low	1	0
arginine	low	3	0
boranes	low	1	0
trichloroacetic acid	medium	11	1
triamcinolone acetonide	low	1	0
triparanol	low	7	0
peracetic acid	low	1	0
dichloroacetic acid	low	3	0
pantothenic acid	low	1	0
dehydrocholic acid	low	1	0
taurocholic acid	low	3	0
methylprednisolone	low	2	0
n-vinyl-2-pyrrolidinone	low	2	0
tolonium chloride	low	1	0
phenothiazine	low	1	0
benzoyl chloride	low	1	0
4-phenylenediamine	low	1	0
acrylonitrile	low	1	0
pyrroles	low	5	0
phenformin	low	1	0
framycetin	medium	3	1
dextrothyroxine	medium	4	1
benzoxazoles	low	1	0
thiazoles	low	1	0
pyrazines	low	1	0
chlormadinone acetate	low	1	0
perfluorobutane	low	1	0
fluorobenzenes	low	3	0
limestone	medium	1	1
chenodeoxycholic acid	low	60	0
reticulin	low	1	0
deoxycytidine	low	1	0
carmine	low	1	0
thorium dioxide	low	1	0
d-alpha tocopherol	low	4	0
neodymium	medium	1	1
osmium	low	1	0
technetium	low	1	0
erbium	medium	3	2
gadolinium	low	4	0
vanadium	low	1	0
yttrium	medium	1	1
silver nitrate	low	1	0
galactose	low	1	0
chlormerodrin	low	1	0
trolamine salicylate	low	26	0
urobilinogen	low	1	0
phytanic acid	low	2	0
cephalexin	low	1	0
fluorides	low	1	0
phenyl acetate	low	7	0
triamcinolone	low	2	0
ursodeoxycholic acid	low	9	0
calcium oxalate	low	1	0
glutamic acid	low	1	0
alovudine	low	1	0
cefazolin	low	1	0
bezafibrate	low	3	0
vx	low	1	0
propiconazole	low	21	0
lovastatin	medium	10	2
simvastatin	low	8	0
pravastatin	medium	7	1
imiquimod	low	1	0
gemcitabine	low	1	0
atorvastatin	low	7	0
colestipol	medium	8	3
mevastatin	low	2	0
metaperiodate	low	1	0
iopamidol	low	2	0
lathosterol	low	2	0
delphinidin	low	3	0
fluorodeoxyglucose f18	low	9	0
fibrinogen	low	2	0
cholest-4-en-3-one	low	1	0
24-methylenecholesterol	low	1	0
cholest-5-ene-3 beta,26-diol	low	1	0
valerates	low	1	0
campestanol	low	1	0
imatinib mesylate	low	1	0
7 alpha-hydroxy-4-cholesten-3-one	low	6	0
methotrexate	low	6	0
ezetimibe	low	14	0
carbodiimides	low	1	0
3,7,12-trihydroxycoprostane	low	3	0
campesterol	low	3	0
cholestane-3,7,12,26-tetrol	low	1	0
cholic acid	low	4	0
deoxycholic acid	low	5	0
cortisone	low	2	0
lanosterol	low	2	0
ritonavir	low	1	0
glycogen	low	4	0
mannose-6-phosphate	low	1	0
fibrin	low	1	0
bradykinin	low	2	0
mevalonic acid	low	5	0
desmosterol	low	2	0
inositol 3-phosphate	low	1	0
griseofulvin	low	2	0
ao 128	low	1	0
tretinoin	low	1	0
arachidonic acid	low	1	0
retinol	low	4	0
oleic acid	low	2	0
cerivastatin	low	1	0
mupirocin	low	1	0
lycopene	low	1	0
diethylstilbestrol	low	1	0
gamma-sitosterol	low	18	0
arsphenamine	low	1	0
melphalan	low	12	0
euscaphic acid	low	1	0
bromochloroacetic acid	low	16	0
squalene	low	2	0
s 1033	low	2	0
leuprolide	low	1	0
mercaptopurine	low	2	0
dihydroxycoprostane	low	1	0
cytellin	low	40	0
cholestane-3,7,12,25-tetrol	low	1	0
17-ketosteroids	low	1	0
osteoprotegerin	low	1	0
bilirubin	low	7	0
vitamin k semiquinone radical	low	1	0
hymecromone	low	1	0
stigmasterol	low	2	0
cholecalciferol	low	3	0
rutin	low	1	0
amphotericin b	low	1	0
coenzyme q10	low	1	0
isotretinoin	low	2	0
pitavastatin	low	1	0
cholesteryl oleate	low	2	0
phenylephrine hydrochloride	low	6	0
acipimox	low	1	0
clobetasol	low	2	0
deamino arginine vasopressin	low	1	0
desonide	low	1	0
barium	low	1	0
aluminum	medium	3	1
arsenic	low	2	0
phosphorus	medium	2	1
triolein	low	2	0
ajmaline	low	1	0
cholestanol	low	45	0
24,25-dihydroxyvitamin d 3	low	1	0
4-methylumbelliferyl oleate	low	1	0
gadolinium dtpa	low	3	0
amoxicillin-potassium clavulanate combination	low	1	0
tak 475	low	1	0
mart-1 antigen	low	4	0
pasireotide	medium	1	1
2-carbomethoxy-8-(3-fluoropropyl)-3-(4-iodophenyl)tropane	low	1	0
nystatin a1	low	1	0
trametinib	low	1	0
phytosterols	low	36	0
acid phosphatase	low	4	0
bleomycetin	medium	3	1
jaw	low	2	0
nad	low	1	0
gastrins	low	1	0
glucagon	low	1	0
cellulose	low	1	0
endothelin-1	low	1	0
phosphatidylcholines	low	9	0
ubiquinone	low	1	0
2-hydroxyursolic acid	low	1	0
27-norcholestane-3,7,12,24,25-pentol	low	1	0
chiniofon	low	1	0
arginine	low	1	0
gdc 0449	low	1	0
plx4032	low	1	0
glycolipids	low	7	0
piperidines	low	2	0
chondroitin	low	1	0
ascorbic acid	low	1	0
minocycline	low	1	0
salicylates	low	1	0
roquinimex	low	1	0
warfarin	low	1	0
cyclin d1	low	1	0
technetium tc 99m sulfur colloid	low	1	0
nitrophenols	low	1	0
gadoxetic acid disodium	low	1	0
vitamin b 12	low	2	0
insulin glargine	low	1	0
moxidectin	low	1	0
cyclosporine	low	1	0
technetium tc 99m medronate	low	5	0
muramidase	low	3	0
exudates	low	3	0
acyclovir	low	1	0
guanine	low	1	0
folic acid	low	1	0
valacyclovir	low	1	0
olanzapine	low	1	0
allopurinol	low	2	0
cholestyramine resin	medium	50	3
eye	low	6	0
pyrimidinones	low	1	0

Protein Targets (2,013)

Protein	Potency Measurements	Inhibition Measurements	Activation Measurements	Drugs
Chain B, pheromone binding protein	0	0	1	1
Chain A, pheromone binding protein	0	0	1	1
Chain A, JmjC domain-containing histone demethylation protein 3A	13	0	0	13
Chain A, RNA-directed RNA polymerase NS5	0	1	0	1
acid sphingomyelinase	3	0	0	3
thioredoxin reductase	41	0	0	41
USP1 protein, partial	42	0	0	42
TDP1 protein	86	0	0	86
vitamin D3 receptor isoform VDRA	34	0	0	34
importin subunit beta-1 isoform 1	11	0	0	11
flap endonuclease 1	15	0	0	15
serine/threonine-protein kinase PLK1	7	0	0	7
snurportin-1	11	0	0	11
peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	11	0	0	11
GTP-binding nuclear protein Ran isoform 1	5	0	0	5
DNA polymerase eta isoform 1	7	0	0	7
DNA polymerase iota isoform a (long)	24	0	0	24
urokinase-type plasminogen activator precursor	16	0	0	16
plasminogen precursor	16	0	0	16
urokinase plasminogen activator surface receptor precursor	16	0	0	16
geminin	70	0	0	70
DNA polymerase kappa isoform 1	19	0	0	19
fibroblast growth factor 22 isoform 1 precursor	0	0	0	1
Mitogen-activated protein kinase 13	0	1	1	2
Beta-lactamase	0	2	0	2
Transthyretin	0	2	2	6
Fatty acid-binding protein, intestinal	0	5	2	7
Fatty acid-binding protein, adipocyte	0	6	3	9
Cyclin-A2	0	1	0	1
Cannabinoid receptor 1	0	0	1	1
Cyclin-dependent kinase 2	0	1	5	6
Choline O-acetyltransferase	0	1	0	1
Mitogen-activated protein kinase 12	0	1	1	2
Guanine nucleotide-binding protein G	7	0	0	7
Fatty acid-binding protein 5	0	4	2	6
Fatty acid-binding protein 5	0	0	2	2
Mitogen-activated protein kinase 11	0	1	3	4
Mitogen-activated protein kinase 14	0	5	5	10
Sodium-dependent dopamine transporter	0	15	0	15
hypoxia-inducible factor 1 alpha subunit	21	0	0	21
RAR-related orphan receptor gamma	76	0	0	76
GLI family zinc finger 3	76	0	0	76
AR protein	99	0	0	99
aldehyde dehydrogenase 1 family, member A1	52	0	0	52
retinoic acid nuclear receptor alpha variant 1	77	0	0	77
retinoid X nuclear receptor alpha	60	0	0	60
estrogen nuclear receptor alpha	115	0	0	115
peroxisome proliferator-activated receptor delta	51	0	0	51
cytochrome P450, family 19, subfamily A, polypeptide 1, isoform CRA_a	52	0	0	52
activating transcription factor 6	28	0	0	28
v-jun sarcoma virus 17 oncogene homolog (avian)	34	0	0	34
Histone H2A.x	30	0	0	30
thyroid hormone receptor beta isoform a	30	0	0	30
heat shock protein beta-1	27	0	0	27
nuclear factor erythroid 2-related factor 2 isoform 1	79	0	0	79
lamin isoform A-delta10	62	0	0	62
Voltage-dependent calcium channel gamma-2 subunit	38	0	0	38
Glutamate receptor 2	39	2	1	44
Protein skinhead-1	0	1	0	1
Monocarboxylate transporter 2	0	3	0	3
Solute carrier family 22 member 20	0	5	0	5
Solute carrier family 22 member 6	0	5	0	5
Chain A, MAJOR APURINIC/APYRIMIDINIC ENDONUCLEASE	39	0	0	39
Chain A, Putative fructose-1,6-bisphosphate aldolase	17	0	0	17
Luciferase	34	0	0	34
acetylcholinesterase	24	0	0	24
Microtubule-associated protein tau	35	0	0	35
estrogen receptor 2 (ER beta)	39	0	0	39
nuclear receptor subfamily 1, group I, member 3	53	0	0	53
progesterone receptor	48	0	0	48
cytochrome P450 family 3 subfamily A polypeptide 4	57	0	0	57
glucocorticoid receptor [Homo sapiens]	79	0	0	79
estrogen-related nuclear receptor alpha	81	0	0	81
farnesoid X nuclear receptor	45	0	0	45
pregnane X nuclear receptor	66	0	0	66
G	40	0	0	40
cytochrome P450 2D6	31	0	0	31
euchromatic histone-lysine N-methyltransferase 2	64	0	0	64
aryl hydrocarbon receptor	39	0	0	39
thyroid stimulating hormone receptor	29	0	0	29
nuclear receptor subfamily 1, group I, member 2	17	0	0	17
thyroid hormone receptor beta isoform 2	66	0	0	66
histone deacetylase 9 isoform 3	7	0	0	7
peripheral myelin protein 22	43	0	0	43
Interferon beta	46	0	0	46
HLA class I histocompatibility antigen, B alpha chain	40	0	0	40
Cellular tumor antigen p53	66	0	0	66
Inositol hexakisphosphate kinase 1	40	0	0	40
ATPase family AAA domain-containing protein 5	28	0	0	28
Ataxin-2	32	0	0	32
cytochrome P450 2C9, partial	40	0	0	40
Free fatty acid receptor 3	0	0	1	1
Free fatty acid receptor 2	0	1	1	2
Tyrosine-protein kinase Lck	0	3	4	7
Tyrosine-protein kinase Fyn	0	4	4	8
Fibrinogen C domain-containing protein 1	0	1	0	1
Monocarboxylate transporter 4	0	0	0	2
Chain A, TYROSYL-DNA PHOSPHODIESTERASE	28	0	0	28
Chain A, Beta-lactamase	21	0	0	21
phosphopantetheinyl transferase	37	0	0	37
GLS protein	25	0	0	25
thyroid stimulating hormone receptor	33	0	0	33
glucocerebrosidase	10	0	0	10
bromodomain adjacent to zinc finger domain 2B	20	0	0	20
Bloom syndrome protein isoform 1	24	0	0	24
histone acetyltransferase KAT2A isoform 1	29	0	0	29
muscarinic acetylcholine receptor M1	19	0	0	19
Fumarate hydratase	19	0	0	19
EWS/FLI fusion protein	43	0	0	43
polyprotein	19	0	0	19
ATP-binding cassette sub-family C member 3	0	49	0	49
Multidrug resistance-associated protein 4	0	50	0	53
Bile salt export pump	0	77	0	78
Hydroxycarboxylic acid receptor 2	0	2	2	4
Canalicular multispecific organic anion transporter 1	0	47	0	47
Chain E, Purine nucleoside phosphorylase	0	1	0	1
Chain A, HADH2 protein	22	0	0	22
Chain B, HADH2 protein	22	0	0	22
Chain A, ATP-DEPENDENT DNA HELICASE Q1	8	0	0	8
Chain A, Ferritin light chain	26	0	0	26
Thymidine kinase	0	2	0	3
Smad3	14	0	0	14
arylsulfatase A	16	0	0	16
hemoglobin subunit beta	3	0	0	3
atrial natriuretic peptide receptor 1 precursor	4	0	0	4
ubiquitin carboxyl-terminal hydrolase 2 isoform a	8	0	0	8
Solute carrier family 22 member 1	0	11	0	15
Solute carrier family 22 member 6	0	10	0	11
Bile salt export pump	0	16	0	17
Purine nucleoside phosphorylase	0	3	0	3
Thymidine kinase, cytosolic	0	3	0	6
POU domain, class 2, transcription factor 2	0	0	0	1
Cytochrome P450 2C9	0	21	3	25
Cytochrome P450 2J2	0	9	0	9
Disintegrin and metalloproteinase domain-containing protein 17	7	0	0	7
Purine nucleoside phosphorylase	0	0	3	3
Solute carrier family 22 member 6	0	4	0	7
Thymidine kinase	0	1	0	1
Solute carrier family 22 member 8	0	5	0	8
Thymidine kinase	0	2	0	3
Chain A, MTA/SAH nucleosidase	0	1	0	1
Chain A, Ribosome-inactivating protein alpha-trichosanthin	0	0	1	1
Chain A, Ricin A chain	0	0	1	1
Chain A, Ribosome-inactivating protein 3	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
Chain A, Phenylethanolamine N-methyltransferase	0	0	1	1
nuclear factor erythroid 2-related factor 2 isoform 2	23	0	0	23
tumor susceptibility gene 101 protein	1	0	0	1
Cyclin-dependent kinase 1	0	1	3	4
Heat shock protein HSP 90-beta	0	1	0	1
Xanthine dehydrogenase/oxidase	0	5	0	5
TAR DNA-binding protein 43	22	0	0	22
Protein mono-ADP-ribosyltransferase PARP15	0	2	0	2
Leucine-rich repeat serine/threonine-protein kinase 2	0	2	1	3
interleukin 8	17	0	0	17
IDH1	24	0	0	24
transcriptional regulator ERG isoform 3	9	0	0	9
ras-related protein Rab-9A	4	0	0	4
survival motor neuron protein isoform d	26	0	0	26
Polyphenol oxidase 2	0	9	0	13
Hypoxanthine-guanine phosphoribosyltransferase	0	0	0	3
Xanthine dehydrogenase/oxidase [Includes: Xanthine dehydrogenase	0	1	0	1
Adenosine receptor A2a	0	11	4	16
Nuclear receptor ROR-gamma	0	1	0	1
Xanthine dehydrogenase/oxidase	0	3	1	5
Shiga toxin subunit A	0	2	0	2
Histamine H3 receptor	0	2	0	4
Thymidylate kinase	0	2	0	2
Reverse transcriptase/RNaseH	0	1	1	3
ATAD5 protein, partial	24	0	0	24
Lysyl oxidase homolog 2	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Protein-lysine 6-oxidase	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Lysyl oxidase homolog 3	0	1	0	1
Lysyl oxidase homolog 4	0	1	0	1
Lysyl oxidase homolog 2	0	1	0	1
Chain A, Cruzipain	15	0	0	15
vitamin D (1,25- dihydroxyvitamin D3) receptor	45	0	0	45
tumor necrosis factor	1	0	0	1
Cytochrome P450 1A2	0	10	2	12
Cytochrome P450 3A4	0	18	1	24
Cytochrome P450 2D6	0	10	2	13
Cytochrome P450 2C19	0	10	1	11
Nuclear receptor ROR-gamma	25	1	2	28
Potassium voltage-gated channel subfamily H member 2	0	16	0	16
Aurora kinase B	0	1	3	4
Broad substrate specificity ATP-binding cassette transporter ABCG2	0	9	0	10
Chain A, retinol dehydratase	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	33	3	2	38
Sex hormone-binding globulin	0	0	6	6
Corticosteroid-binding globulin	0	4	0	4
Glucose-6-phosphate 1-dehydrogenase	0	4	0	4
Androgen receptor	0	19	0	19
Gamma-aminobutyric acid receptor subunit beta-1	33	3	2	38
Gamma-aminobutyric acid receptor subunit delta	33	3	2	38
Gamma-aminobutyric acid receptor subunit gamma-2	33	3	2	38
Gamma-aminobutyric acid receptor subunit alpha-5	33	3	2	38
Gamma-aminobutyric acid receptor subunit alpha-3	33	3	2	38
Gamma-aminobutyric acid receptor subunit gamma-1	33	3	2	38
Gamma-aminobutyric acid receptor subunit alpha-2	33	3	2	38
Gamma-aminobutyric acid receptor subunit alpha-4	33	3	2	38
Gamma-aminobutyric acid receptor subunit gamma-3	33	3	2	38
Gamma-aminobutyric acid receptor subunit alpha-6	33	3	2	38
Solute carrier organic anion transporter family member 1A1	0	2	0	4
Gamma-aminobutyric acid receptor subunit alpha-1	33	4	2	39
Gamma-aminobutyric acid receptor subunit beta-3	33	3	2	38
Gamma-aminobutyric acid receptor subunit beta-2	33	3	2	38
G-protein coupled bile acid receptor 1	0	1	6	7
GABA theta subunit	33	3	2	38
Gamma-aminobutyric acid receptor subunit epsilon	33	3	2	38
Maltase-glucoamylase, intestinal	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
Sucrase-isomaltase, intestinal	0	1	0	1
Glycogen debranching enzyme	0	1	0	1
Lysosomal alpha-glucosidase	0	1	0	1
D(1A) dopamine receptor	9	0	0	9
neuropeptide S receptor isoform A	12	0	0	12
Chain A, ADIPOCYTE LIPID-BINDING PROTEIN	0	0	1	1
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, SERUM ALBUMIN	0	0	2	2
Chain A, 2-oxoglutarate Oxygenase	24	0	0	24
15-lipoxygenase, partial	13	0	0	13
thioredoxin glutathione reductase	16	0	0	16
heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa)	4	0	0	4
cellular tumor antigen p53 isoform a	9	0	0	9
15-hydroxyprostaglandin dehydrogenase [NAD(+)] isoform 1	15	0	0	15
nuclear receptor ROR-gamma isoform 1	29	0	0	29
lethal(3)malignant brain tumor-like protein 1 isoform I	2	0	0	2
cytochrome P450 3A4 isoform 1	33	0	0	33
DNA dC->dU-editing enzyme APOBEC-3G isoform 1	4	0	0	4
caspase-1 isoform alpha precursor	5	0	0	5
Fatty-acid amide hydrolase 1	0	2	0	2
Polyunsaturated fatty acid lipoxygenase ALOX15B	9	0	0	9
Prostaglandin G/H synthase 1	0	4	0	6
Trypsin	0	2	0	2
Coagulation factor VII	0	3	0	3
60 kDa chaperonin	0	3	0	3
60 kDa heat shock protein, mitochondrial	0	3	0	3
Aromatase	0	3	0	3
Tissue factor	0	4	0	4
Prostaglandin G/H synthase 2	0	14	3	18
Nuclear receptor subfamily 4 group A member 2	0	0	5	5
Histamine H2 receptor	19	1	1	24
10 kDa heat shock protein, mitochondrial	0	3	0	3
Calmodulin	0	1	1	3
Prostaglandin G/H synthase 2	0	6	0	7
Solute carrier organic anion transporter family member 2A1	0	0	0	1
Thiosulfate sulfurtransferase	0	3	0	3
Lanosterol 14-alpha demethylase	0	7	0	8
60 kDa chaperonin	0	3	0	3
10 kDa chaperonin	0	3	0	3
Solute carrier organic anion transporter family member 1B3	0	15	0	20
Cytosolic phospholipase A2 gamma	0	2	0	2
Transient receptor potential cation channel subfamily V member 2	0	4	0	4
Solute carrier organic anion transporter family member 1B1	0	16	0	23
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
Chain E, LYSINE, ARGININE, ORNITHINE-BINDING PROTEIN	0	0	2	2
NFKB1 protein, partial	7	0	0	7
alpha-galactosidase	6	0	0	6
cytochrome P450 2C19 precursor	12	0	0	12
chromobox protein homolog 1	33	0	0	33
lethal factor (plasmid)	15	0	0	15
Nitric oxide synthase, endothelial	0	0	0	2
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, brain	0	0	0	1
Nitric oxide synthase, inducible	0	1	0	2
Nitric oxide synthase, inducible	0	0	1	3
Cationic amino acid transporter 3	0	1	0	1
ATP-dependent phosphofructokinase	23	0	0	23
Chain A, Hyaluronidase, phage associated	0	1	0	1
Pancreatic alpha-amylase	0	2	0	2
Albumin	0	2	0	3
Urease	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	0	0	1
Tyrosinase	0	5	0	6
Alpha-2B adrenergic receptor	0	14	4	19
Spike glycoprotein	33	1	3	37
Hyaluronate lyase	0	1	0	1
Prolyl hydroxylase EGLN2	0	0	0	1
Egl nine homolog 1	0	0	0	1
Prolyl hydroxylase EGLN3	0	0	0	1
Hypoxia-inducible factor 1-alpha inhibitor	0	0	0	1
Solute carrier family 23 member 1	0	1	0	1
Metabotropic glutamate receptor 6	0	2	2	5
Excitatory amino acid transporter 4	0	2	0	2
Glutamate transporter homolog	0	0	1	1
Carbonic anhydrase 1	0	14	0	22
Carbonic anhydrase 2	0	17	2	29
N(4)-(beta-N-acetylglucosaminyl)-L-asparaginase	0	1	0	1
5-hydroxytryptamine receptor 1D	0	0	0	3
Glutamate receptor ionotropic, NMDA 1	0	6	2	13
Excitatory amino acid transporter 1	0	3	0	4
Excitatory amino acid transporter 2	0	3	0	4
Excitatory amino acid transporter 3	0	3	0	4
Glutamate receptor ionotropic, NMDA 2A	0	6	2	13
Glutamate receptor ionotropic, NMDA 2B	0	6	2	14
Glutamate receptor ionotropic, NMDA 2C	0	6	2	13
Metabotropic glutamate receptor 1	0	1	2	4
Metabotropic glutamate receptor 2	0	1	2	4
Carbonic anhydrase-like protein, putative	0	0	0	7
Glutamate receptor ionotropic, NMDA 2D	0	6	2	13
Glutamate receptor ionotropic, NMDA 3B	0	6	2	13
Carbonic anhydrase 4	0	0	0	3
Glutamate receptor ionotropic, NMDA 3A	0	6	2	13
Chain A, Phospholipase A2 isoform 3	0	0	1	1
GTP-binding protein (rab7)	0	0	1	1
ras protein, partial	0	0	1	1
hypothetical protein, conserved	2	0	0	2
Rac1 protein	0	0	1	1
cell division cycle 42 (GTP binding protein, 25kDa), partial	0	0	1	1
Prostaglandin-H2 D-isomerase	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	3
Epidermal growth factor receptor	0	7	3	10
Fatty acid-binding protein, liver	0	8	2	10
Integrin beta-3	6	1	1	8
Myeloperoxidase	0	4	0	4
Prostaglandin G/H synthase 1	0	4	1	6
Seed linoleate 13S-lipoxygenase-1	0	2	0	2
Integrin alpha-IIb	6	1	1	8
Glutathione hydrolase 1 proenzyme	0	1	0	1
Prostaglandin G/H synthase 1	0	7	0	7
Adenosine receptor A1	0	6	0	11
Adenosine receptor A2a	0	4	0	10
Substance-P receptor	0	4	0	4
Urotensin-2 receptor	0	1	0	1
4-aminobutyrate aminotransferase, mitochondrial	0	1	0	1
Ras-related protein Rab-2A	0	0	1	1
Rho-associated protein kinase 2	0	2	0	2
Nicotinate phosphoribosyltransferase	0	3	0	3
Sigma non-opioid intracellular receptor 1	0	11	1	12
Sigma non-opioid intracellular receptor 1	0	2	2	4
SMAD family member 2	24	0	0	24
SMAD family member 3	24	0	0	24
caspase 7, apoptosis-related cysteine protease	16	0	0	16
peroxisome proliferator activated receptor gamma	48	0	0	48
caspase-3	16	0	0	16
Caspase-7	9	0	0	9
caspase-3	9	0	0	9
Solute carrier organic anion transporter family member 2B1	0	6	0	9
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	8	0	8
ATP-dependent translocase ABCB1	0	14	1	20
Insulin receptor	0	6	0	6
Dipeptidyl peptidase 4	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	8	0	8
Histone deacetylase 1	0	4	0	4
Histone deacetylase 2	0	4	0	4
Histone deacetylase 6	0	4	0	4
P53	1	0	0	1
peripheral myelin protein 22 isoform 1	14	0	0	14
M-phase phosphoprotein 8	12	0	0	12
muscleblind-like protein 1 isoform 1	14	0	0	14
Protein-arginine deiminase type-4	0	4	0	4
regulator of G-protein signaling 4	16	0	0	16
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Sodium- and chloride-dependent betaine transporter	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Proton-coupled amino acid transporter 1	0	3	0	4
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
PPM1D protein	7	0	0	7
thyrotropin-releasing hormone receptor	4	0	0	4
nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 (p105), isoform CRA_a	22	0	0	22
Cytochrome P450 26A1	0	1	0	1
Retinoic acid receptor alpha	0	3	4	10
Retinoic acid receptor beta	0	3	4	10
Retinoic acid receptor gamma	0	3	4	10
Retinoic acid receptor RXR-alpha	0	4	6	11
Retinoic acid receptor RXR-alpha	0	2	4	6
Retinoic acid receptor RXR-beta	0	3	3	6
Retinoic acid receptor RXR-beta	0	2	4	6
Retinoic acid receptor RXR-gamma	0	2	4	6
Type-1 angiotensin II receptor	0	1	2	3
Retinoic acid receptor RXR-gamma	0	3	3	6
Type-2 angiotensin II receptor	0	3	1	4
Oxysterols receptor LXR-beta	0	0	1	1
Retinoic acid receptor RXR-alpha	0	0	1	1
Oxysterols receptor LXR-alpha	0	0	1	1
Sigma non-opioid intracellular receptor 1	0	6	1	7
Cytochrome P450 26B1	0	1	0	1
Glutamate receptor ionotropic, NMDA 2D	0	2	2	4
Glutamate receptor ionotropic, NMDA 3B	0	2	2	4
5-hydroxytryptamine receptor 4	0	20	3	23
Muscarinic acetylcholine receptor M1	0	5	4	9
Muscarinic acetylcholine receptor M3	0	5	4	9
Muscarinic acetylcholine receptor M4	0	5	4	9
Muscarinic acetylcholine receptor M5	0	5	4	9
Muscarinic acetylcholine receptor M2	0	5	4	9
Peroxisome proliferator-activated receptor alpha	0	0	4	4
Peroxisome proliferator-activated receptor delta	0	0	1	1
Peroxisome proliferator-activated receptor gamma	0	3	11	15
Peroxisome proliferator-activated receptor gamma	0	0	5	5
Peroxisome proliferator-activated receptor delta	0	0	2	3
Glutamate receptor ionotropic, NMDA 1	0	2	2	4
Peroxisome proliferator-activated receptor alpha	3	1	7	12
Glutamate receptor ionotropic, NMDA 2A	0	2	2	4
Glutamate receptor ionotropic, NMDA 2B	0	2	2	4
Glutamate receptor ionotropic, NMDA 2C	0	2	2	4
Glutamate receptor ionotropic, NMDA 3A	0	2	2	4
Caspase-7	3	0	0	3
Inositol monophosphatase 1	10	0	0	10
Delta-type opioid receptor	0	3	1	5
Microsomal triglyceride transfer protein large subunit	0	1	0	1
Angiotensin-converting enzyme	0	1	0	2
B2 bradykinin receptor	0	1	0	1
B2 bradykinin receptor	0	2	1	5
B1 bradykinin receptor	0	1	0	1
Olfactory receptor 51E2	0	1	3	4
Carbonic anhydrase 4	0	8	0	13
Carbonic anhydrase	0	3	0	8
Carbonic anhydrase 15	0	6	0	11
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 3	0	1	0	1
Potassium channel subfamily K member 2	0	2	3	5
Potassium channel subfamily K member 9	0	1	0	1
apical membrane antigen 1, AMA1	9	0	0	9
67.9K protein	15	0	0	15
luciferase	2	0	0	2
potassium voltage-gated channel subfamily H member 2 isoform d	26	0	0	26
mitogen-activated protein kinase 1	19	0	0	19
eyes absent homolog 2 isoform a	2	0	0	2
Tyrosine-protein phosphatase non-receptor type 1	0	6	0	8
Glutamate receptor 1	1	2	1	6
Glutamate receptor 3	1	2	1	6
Glutamate receptor 4	1	2	1	6
Tyrosine-protein phosphatase 1	0	1	0	1
Alpha-synuclein	6	5	0	11
C-terminal-binding protein 1	2	0	0	2
Solute carrier family 15 member 1	0	6	0	7
Solute carrier family 22 member 11	0	2	0	3
Solute carrier family 22 member 8	0	4	0	5
Solute carrier family 15 member 1	0	2	0	2
B2 metallo-beta-lactamase	0	0	0	1
Solute carrier family 15 member 2	0	1	0	1
Solute carrier family 15 member 2	0	2	0	3
Alpha-2A adrenergic receptor	0	14	4	19
Vitamin D3 receptor	0	5	5	12
Alpha-2C adrenergic receptor	0	12	4	17
Ileal sodium/bile acid cotransporter	0	4	0	5
Bile acid receptor	0	0	1	1
Bile acid receptor	0	1	4	5
GALC protein	9	0	0	9
Thrombopoietin	5	0	0	5
hypoxia-inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)	16	0	0	16
FAD-linked sulfhydryl oxidase ALR	0	0	0	2
Carbonic anhydrase 12	0	6	0	11
Carbonic anhydrase 9	0	9	1	16
parathyroid hormone/parathyroid hormone-related peptide receptor precursor	11	0	0	11
Glucocorticoid receptor	0	22	3	30
Glycine receptor subunit alpha-1	0	22	0	22
Glycine receptor subunit beta	0	22	0	22
Glycine receptor subunit alpha-2	0	22	0	22
Glycine receptor subunit alpha-3	0	22	0	22
Proteasome subunit beta type-11	0	0	0	1
NADPH oxidase 1	0	2	0	2
Snq2p	0	0	0	2
Adenylate cyclase type 1	0	3	0	3
Spike glycoprotein	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
cytochrome P450 2D6 isoform 1	13	0	0	13
atrial natriuretic peptide receptor 2 precursor	2	0	0	2
serine/threonine-protein kinase mTOR isoform 1	8	0	0	8
Proteasome subunit alpha type-7	0	0	0	1
Transmembrane protease serine 2	0	1	3	4
Transient receptor potential cation channel subfamily V member 1	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1F	0	5	0	5
Albumin	0	4	7	13
Albumin	0	0	5	5
Major prion protein	0	0	2	2
Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	0	2	0	2
Receptor tyrosine-protein kinase erbB-2	0	2	1	3
Major prion protein	0	0	1	1
Procathepsin L	0	2	3	5
Aldo-keto reductase family 1 member B1	0	23	0	23
Muscarinic acetylcholine receptor M2	0	13	1	14
Muscarinic acetylcholine receptor M4	0	13	0	13
5-hydroxytryptamine receptor 1A	0	6	1	7
5-hydroxytryptamine receptor 2C	0	8	0	9
Muscarinic acetylcholine receptor M5	0	12	0	12
Replicase polyprotein 1a	0	1	3	4
Replicase polyprotein 1ab	0	1	3	4
Replicase polyprotein 1ab	0	2	3	5
Cys-loop ligand-gated ion channel	0	1	0	1
Calmodulin-1	0	2	1	3
Replicase polyprotein 1ab	0	4	3	7
Muscarinic acetylcholine receptor M1	0	16	3	20
Polyunsaturated fatty acid lipoxygenase ALOX15	0	6	0	6
Angiotensin-converting enzyme	0	6	0	6
D(2) dopamine receptor	0	11	2	16
5-hydroxytryptamine receptor 2A	0	8	0	8
Alpha-1B adrenergic receptor	0	25	1	26
Sphingomyelin phosphodiesterase	0	1	0	1
D	0	5	0	5
D(3) dopamine receptor	0	7	0	7
5-hydroxytryptamine receptor 1A	0	15	1	17
Alpha-2B adrenergic receptor	0	4	1	5
D(2) dopamine receptor	0	3	0	3
Muscarinic acetylcholine receptor M3	0	16	1	17
Proteasome subunit beta type-1	0	0	0	1
Substance-K receptor	0	10	0	10
D(1A) dopamine receptor	0	13	1	16
D(4) dopamine receptor	0	8	1	12
D(1B) dopamine receptor	0	3	0	5
Adenylate cyclase type 3	0	3	0	3
Alpha-2C adrenergic receptor	0	4	1	5
UDP-glucuronosyltransferase 1A4	0	1	0	4
Alpha-2A adrenergic receptor	0	4	1	5
Alpha-1D adrenergic receptor	0	10	1	11
Sodium-dependent noradrenaline transporter	0	21	1	22
Sodium-dependent dopamine transporter	0	6	0	6
Histamine H2 receptor	0	11	2	13
Alpha-1D adrenergic receptor	0	14	1	16
D(1B) dopamine receptor	0	4	0	4
Proteasome subunit alpha type-1	0	0	0	1
Proteasome subunit alpha type-2	0	0	0	1
Proteasome subunit alpha type-3	0	0	0	1
Proteasome subunit alpha type-4	0	0	0	1
Adenylate cyclase type 2	0	3	0	3
Adenylate cyclase type 4	0	3	0	3
Proteasome subunit beta type-8	0	0	0	1
Proteasome subunit beta type-9	0	0	0	1
Proteasome subunit alpha type-5	0	0	0	1
Proteasome subunit beta type-4	0	0	0	1
Proteasome subunit beta type-6	0	0	0	1
Proteasome subunit beta type-5	0	0	0	1
5-hydroxytryptamine receptor 2A	0	18	1	19
5-hydroxytryptamine receptor 2C	0	20	1	21
5-hydroxytryptamine receptor 1B	0	9	0	9
Trypanothione reductase	0	2	0	2
D(4) dopamine receptor	0	5	0	5
5-hydroxytryptamine receptor 2B	0	7	0	7
Histamine H1 receptor	0	3	3	8
Sodium-dependent serotonin transporter	0	18	0	18
Melanocortin receptor 4	0	4	0	4
5-hydroxytryptamine receptor 7	0	3	0	3
Melanocortin receptor 5	0	4	0	4
Pleiotropic ABC efflux transporter of multiple drugs	0	2	0	4
5-hydroxytryptamine receptor 7	0	4	1	5
Histamine H1 receptor	0	12	3	15
Mu-type opioid receptor	0	15	4	21
D(3) dopamine receptor	0	14	1	18
Sodium channel protein type 1 subunit alpha	0	4	0	4
Sodium channel protein type 4 subunit alpha	0	3	0	4
Adenylate cyclase type 8	0	3	0	3
Proteasome subunit beta type-10	0	0	0	1
Delta-type opioid receptor	0	9	3	14
Kappa-type opioid receptor	0	13	2	18
5-hydroxytryptamine receptor 2B	0	24	1	25
Melanocortin receptor 3	0	4	0	4
Alpha-1A adrenergic receptor	0	26	1	27
Proteasome subunit beta type-3	0	0	0	1
Proteasome subunit beta type-2	0	0	0	1
D(1A) dopamine receptor	4	1	0	5
5-hydroxytryptamine receptor 6	0	16	1	17
5-hydroxytryptamine receptor 7	0	3	0	3
Gastrin/cholecystokinin type B receptor	0	2	0	2
Proteasome subunit alpha type-6	0	0	1	2
D(2) dopamine receptor	0	6	0	7
Aldehyde oxidase 1	0	1	0	1
Sodium channel protein type 7 subunit alpha	0	2	0	2
Voltage-dependent L-type calcium channel subunit alpha-1D	0	5	0	5
Adenylate cyclase type 6	0	3	0	3
Adenylate cyclase type 5	0	3	0	3
Aldehyde oxidase	0	4	0	4
Voltage-dependent L-type calcium channel subunit alpha-1S	0	5	0	5
Voltage-dependent L-type calcium channel subunit alpha-1C	0	6	0	6
Sodium channel protein type 5 subunit alpha	0	6	0	6
Sodium channel protein type 9 subunit alpha	0	3	0	3
Nuclear receptor subfamily 3 group C member 3	0	5	0	5
Adenylyl cyclase 7	0	3	0	3
Proteasome subunit alpha-type 8	0	0	0	1
D	0	2	0	2
Sodium channel protein type 2 subunit alpha	0	4	0	4
Proteasome subunit beta type-7	0	0	0	1
Angiotensin-converting enzyme 2	0	1	3	4
Sodium channel protein type 3 subunit alpha	0	4	0	4
Sodium channel protein type 11 subunit alpha	0	2	0	2
Sodium channel protein type 8 subunit alpha	0	2	0	2
Histamine H3 receptor	0	2	2	4
Sodium channel protein type 10 subunit alpha	0	2	0	2
Glycine receptor subunit alpha-1	0	0	1	1
Vitamin D3 receptor	0	0	1	1
Cytochrome P450 144	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Steroid C26-monooxygenase	0	0	2	2
Ghrelin O-acyltransferase	0	1	0	1
Ubiquitin carboxyl-terminal hydrolase 2	0	2	0	2
Phospholipase A2	0	0	1	1
G-protein coupled bile acid receptor 1	0	1	0	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Acetylcholinesterase	0	0	1	1
Chain A, Putative Glycine Betaine-binding Abc Transporter Protein	0	0	1	1
Chain A, PUTATIVE GLYCINE BETAINE-BINDING ABC TRANSPORTER PROTEIN	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Glycine betaine/carnitine/choline-binding protein	0	0	1	1
Chain A, Choline-binding protein	0	0	1	1
Solute carrier family 22 member 1	0	2	0	3
Solute carrier family 22 member 2	0	6	0	8
Solute carrier family 22 member 2	0	2	0	2
Neuronal acetylcholine receptor subunit alpha-3	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-4	3	2	0	5
Neuronal acetylcholine receptor subunit alpha-2	0	1	0	1
Neuronal acetylcholine receptor subunit beta-2	3	2	0	5
Neuronal acetylcholine receptor subunit beta-3	0	1	0	1
Neuronal acetylcholine receptor subunit beta-4	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-5	0	1	0	1
Acetylcholinesterase	0	8	0	8
Sodium- and chloride-dependent creatine transporter 1	0	1	0	1
Choline O-acetyltransferase	0	1	0	2
Neuronal acetylcholine receptor subunit alpha-6	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-9	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-7	0	1	1	2
Solute carrier family 22 member 1	0	5	0	9
High affinity choline transporter 1	0	1	0	1
Neuronal acetylcholine receptor subunit alpha-10	0	1	0	1
Solute carrier family 22 member 2	0	6	0	8
endonuclease IV	7	0	0	7
PAX8	0	0	0	1
pregnane X receptor	13	0	0	13
nuclear receptor subfamily 0 group B member 1	0	1	0	1
cytochrome P450 2C9 precursor	12	0	0	12
steroidogenic factor 1	0	1	0	1
Solute carrier family 22 member 3	0	6	0	7
Tubulin alpha-1A chain	0	2	1	3
Tubulin beta chain	0	2	1	3
Plasma kallikrein	0	0	0	6
Tubulin beta-4A chain	0	2	2	5
ATP-dependent translocase ABCB1	0	4	0	4
Tubulin beta chain	0	2	2	5
Tubulin alpha-3C chain	0	2	2	5
Serine/threonine-protein kinase pim-1	0	1	3	4
ATP-dependent translocase ABCB1	0	4	0	4
Tubulin alpha-1B chain	0	2	2	5
Tubulin alpha-4A chain	0	2	2	5
Tubulin beta-4B chain	0	2	2	5
Vesicular acetylcholine transporter	0	1	0	1
Tubulin beta-3 chain	0	2	2	5
Tubulin beta-2A chain	0	2	2	5
Tubulin polymerization-promoting protein	0	0	1	1
Tubulin beta-8 chain	0	2	2	5
Tubulin beta-2B chain	0	2	0	2
Tubulin alpha-3E chain	0	2	2	5
Tubulin alpha-1A chain	0	2	2	5
Similar to alpha-tubulin isoform 1	0	1	0	1
Similar to alpha-tubulin isoform 1	0	1	0	1
CREB-binding protein	1	1	0	2
Tubulin alpha-1C chain	0	2	2	5
Tubulin beta-6 chain	0	2	2	5
Tubulin beta-2B chain	0	2	2	5
Tubulin beta-1 chain	0	2	2	5
dopamine D1 receptor	4	0	0	4
Potassium voltage-gated channel subfamily A member 1	0	0	1	1
Multidrug and toxin extrusion protein 1	0	8	0	8
glp-1 receptor, partial	17	0	0	17
LMP1 [Human herpesvirus 4]	0	0	0	2
nuclear receptor coactivator 1 isoform 1 [Homo sapiens]	0	2	0	2
transactivating tegument protein VP16 [Human herpesvirus 1]	0	3	0	3
nuclear receptor coactivator 3 isoform a	0	2	0	2
Thymidine kinase 2, mitochondrial	0	1	0	1
Thymidine kinase	0	2	0	3
Thymidylate synthase	0	3	0	5
Thymidine kinase	0	1	0	1
Deoxycytidine kinase	0	0	3	6
Probable deoxycytidylate deaminase	0	0	0	2
Cytidine deaminase	0	1	0	4
E3 ubiquitin-protein ligase Mdm2	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	1
Deoxynucleoside kinase	0	1	0	1
Deoxycytidine kinase	0	0	0	1
Rap guanine nucleotide exchange factor 3	5	0	0	5
Glutathione S-transferase P	0	1	0	1
Alpha-tocopherol transfer protein	0	0	1	1
6-hydroxymethyl-7,8-dihydropterin pyrophosphokinase	0	1	0	1
Dihydrofolate reductase	0	3	0	3
Vasopressin V2 receptor	0	1	1	2
Oxytocin receptor	0	0	1	1
Vasopressin V1a receptor	0	6	2	8
Vasopressin V1b receptor	0	1	1	2
Translocator protein	0	1	0	1
Vasopressin V2 receptor	0	1	1	2
Vascular endothelial growth factor receptor 2	0	2	1	3
Lactoylglutathione lyase	0	2	0	2
Histone acetyltransferase p300	0	1	0	1
Chain A, STEROID DELTA-ISOMERASE	0	0	1	1
Steroid Delta-isomerase	0	0	1	1
Thymidine kinase 2	0	1	0	1
AAA family ATPase	0	0	0	2
Solute carrier family 22 member 3	0	1	0	1
Thyroid hormone receptor beta	0	3	0	3
Solute carrier organic anion transporter family member 1C1	0	3	0	3
Nicotinamide phosphoribosyltransferase	0	0	1	1
ATP-binding cassette sub-family C member 8	0	2	1	3
ATP-sensitive inward rectifier potassium channel 11	0	2	1	3
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 1, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 3, mitochondrial	0	1	0	1
[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial	0	1	0	1
histone-lysine N-methyltransferase 2A isoform 2 precursor	5	0	0	5
high affinity choline transporter 1 isoform a	0	1	0	1
Nuclear receptor subfamily 1 group I member 2	0	1	4	5
Estrogen receptor	0	8	2	10
Beta-1 adrenergic receptor	0	6	1	7
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	2
Adenosine receptor A3	0	18	1	19
Thromboxane-A synthase	0	5	0	5
Adenosine receptor A1	0	10	1	13
Estrogen-related receptor gamma	0	0	1	1
UDP-glucose 4-epimerase	0	1	0	1
Estrogen receptor beta	0	5	2	7
Cysteinyl leukotriene receptor 1	0	2	0	2
Cereblon isoform 4	0	4	0	4
Insulin-like growth factor-binding protein 5	0	0	1	1
Protein cereblon	0	4	1	6
huntingtin isoform 2	4	0	0	4
Histamine N-methyltransferase	0	0	0	1
Calcium release-activated calcium channel protein 1	0	2	0	2
Protein orai-2	0	1	0	1
Protein orai-3	0	1	0	1
Histamine H4 receptor	0	2	2	4
5-hydroxytryptamine receptor 1D	0	2	0	2
5-hydroxytryptamine receptor 1F	0	2	0	2
5-hydroxytryptamine receptor 6	0	1	0	1
Histamine H1 receptor	0	5	1	6
5-hydroxytryptamine receptor 5A	0	1	0	1
5-hydroxytryptamine receptor 5B	0	1	0	1
5-hydroxytryptamine receptor 3A	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
5-hydroxytryptamine receptor 3B	0	1	0	1
Endothelin-1 receptor	0	2	1	3
lysosomal alpha-glucosidase preproprotein	8	0	0	8
Vpr	5	0	0	5
Cytochrome P450 2B1	0	1	0	1
Cytochrome P450 2B6	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	5	0	9
3-oxo-5-alpha-steroid 4-dehydrogenase 1	0	1	0	1
Sulfotransferase 1A1	0	2	1	4
Nuclear receptor subfamily 1 group I member 3	0	1	0	1
Multidrug and toxin extrusion protein 2	0	3	0	3
Tyrosyl-DNA phosphodiesterase 1	0	2	0	2
UDP-glucuronosyltransferase 2B7	0	3	0	6
UDP-glucuronosyltransferase 1A3	0	0	0	1
Sodium/bile acid cotransporter	0	5	0	6
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
NPC1-like intracellular cholesterol transporter 1	0	1	0	1
nonstructural protein 1	7	0	0	7
serine-protein kinase ATM isoform a	3	0	0	3
Fatty acid-binding protein, liver	0	2	1	3
Beta-3 adrenergic receptor	0	6	1	7
Cruzipain	0	2	0	2
Peroxisome proliferator-activated receptor alpha	0	0	1	1
Cocaine esterase	0	3	0	4
Androgen receptor	0	7	1	8
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Arylacetamide deacetylase	0	0	0	1
Chain A, Dihydrofolate reductase	0	0	1	1
DNA polymerase beta	6	0	0	6
Thymidylate synthase	0	4	0	4
Dihydrofolate reductase	0	2	3	5
Aldo-keto reductase family 1 member B1	0	4	0	4
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Solute carrier organic anion transporter family member 1A3	0	3	0	7
Folylpolyglutamate synthase, mitochondrial	0	1	0	4
Multidrug resistance associated protein	0	2	0	5
Menin	0	0	1	1
Lecithin retinol acyltransferase	0	1	0	1
30S ribosomal protein S6	0	1	0	1
30S ribosomal protein S7	0	1	0	1
50S ribosomal protein L15	0	1	0	1
50S ribosomal protein L10	0	1	0	1
50S ribosomal protein L11	0	1	0	1
50S ribosomal protein L7/L12	0	1	0	1
50S ribosomal protein L19	0	1	0	1
50S ribosomal protein L1	0	1	0	1
50S ribosomal protein L20	0	1	0	1
50S ribosomal protein L27	0	1	0	1
50S ribosomal protein L28	0	1	0	1
50S ribosomal protein L29	0	1	0	1
50S ribosomal protein L31	0	1	0	1
50S ribosomal protein L31 type B	0	1	0	1
50S ribosomal protein L32	0	1	0	1
50S ribosomal protein L33	0	1	0	1
50S ribosomal protein L34	0	1	0	1
50S ribosomal protein L35	0	1	0	1
50S ribosomal protein L36	0	1	0	1
30S ribosomal protein S10	0	1	0	1
30S ribosomal protein S11	0	1	0	1
30S ribosomal protein S12	0	1	0	1
30S ribosomal protein S13	0	1	0	1
30S ribosomal protein S16	0	1	0	1
30S ribosomal protein S18	0	1	0	1
30S ribosomal protein S19	0	1	0	1
30S ribosomal protein S20	0	1	0	1
30S ribosomal protein S2	0	1	0	1
30S ribosomal protein S3	0	1	0	1
30S ribosomal protein S4	0	1	0	1
30S ribosomal protein S5	0	1	0	1
30S ribosomal protein S8	0	1	0	1
30S ribosomal protein S9	0	1	0	1
50S ribosomal protein L13	0	1	0	1
50S ribosomal protein L14	0	1	0	1
50S ribosomal protein L16	0	1	0	1
50S ribosomal protein L23	0	1	0	1
30S ribosomal protein S15	0	1	0	1
50S ribosomal protein L17	0	1	0	1
50S ribosomal protein L21	0	1	0	1
50S ribosomal protein L30	0	1	0	1
50S ribosomal protein L6	0	1	0	1
30S ribosomal protein S14	0	1	0	1
30S ribosomal protein S17	0	1	0	1
30S ribosomal protein S1	0	1	0	1
50S ribosomal protein L18	0	1	0	1
Lethal factor	0	1	0	1
50S ribosomal protein L2	0	1	0	1
50S ribosomal protein L3	0	1	0	1
50S ribosomal protein L24	0	1	0	1
50S ribosomal protein L4	0	1	0	1
50S ribosomal protein L22	0	1	0	1
50S ribosomal protein L5	0	1	0	1
30S ribosomal protein S21	0	1	0	1
50S ribosomal protein L25	0	1	0	1
50S ribosomal protein L36 2	0	1	0	1
Protein Rev	0	0	1	1
Aminoglycoside 3'-phosphotransferase	0	0	0	1
Sodium-dependent serotonin transporter	0	2	0	2
Smoothened homolog	0	1	1	2
Sonic hedgehog protein	0	1	0	2
Sonic hedgehog protein	0	1	0	1
Smoothened homolog	0	2	2	4
Chain A, DEOXYNUCLEOSIDE KINASE	0	1	0	1
Equilibrative nucleoside transporter 1	0	1	0	1
Cytochrome P450 2C8	0	3	0	4
Cannabinoid receptor 2	0	0	1	1
Guanylate cyclase soluble subunit alpha-1	0	0	1	1
Guanylate cyclase soluble subunit beta-1	0	0	1	1
CDGSH iron-sulfur domain-containing protein 1	0	4	0	4
Chain A, GLUTAMATE RECEPTOR SUBUNIT 2	0	1	0	1
Chain A, Glutamate Receptor Subunit 2	0	1	0	1
Chain B, Glutamate Receptor Subunit 2	0	1	0	1
Chain A, Slr1257 protein	0	0	1	1
Chain A, Glucosamine--fructose-6-phosphate aminotransferase [isomerizing]	0	1	0	1
beta-2 adrenergic receptor	2	0	0	2
Metabotropic glutamate receptor 8	0	2	0	2
Glutathione reductase, mitochondrial	0	3	0	4
Bifunctional aspartokinase/homoserine dehydrogenase 1	0	1	0	1
Prothrombin	0	0	2	2
ATP-citrate synthase	0	1	0	1
Glutamate receptor ionotropic, kainate 1	0	2	1	3
Metabotropic glutamate receptor 1	0	1	1	2
Metabotropic glutamate receptor 2	0	0	1	1
Metabotropic glutamate receptor 3	0	0	1	1
Metabotropic glutamate receptor 4	0	1	1	2
Metabotropic glutamate receptor 5	0	1	2	3
Metabotropic glutamate receptor 6	0	0	1	1
Metabotropic glutamate receptor 7	0	0	1	1
Glutamate receptor ionotropic, kainate 1	0	1	1	2
Metabotropic glutamate receptor 5	0	1	1	3
Glutamate receptor ionotropic, kainate 2	0	2	1	3
Glutamate receptor 1	0	2	1	3
Glutamate receptor 2	0	2	1	3
Glutamate receptor 3	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	2	0	2
Metabotropic glutamate receptor 8	0	0	1	1
Glutamate receptor 4	0	2	1	3
Excitatory amino acid transporter 3	0	0	0	1
Glutamate racemase	0	0	0	1
Metabotropic glutamate receptor 8	0	1	1	2
Fatty-acid amide hydrolase 1	0	1	0	1
Glutamate receptor ionotropic, kainate 4	0	2	0	2
Glutamate carboxypeptidase 2	0	1	0	1
Glutamate receptor ionotropic, kainate 2	0	1	1	2
Glutamate receptor ionotropic, kainate 3	0	1	0	1
Metabotropic glutamate receptor 7	0	1	1	3
Metabotropic glutamate receptor 3	0	1	1	3
Metabotropic glutamate receptor 4	0	1	1	3
Glutamate receptor ionotropic, kainate 5	0	1	0	1
Glutamate receptor ionotropic, kainate 5	0	2	0	2
Glutamate racemase	0	0	0	1
Prolyl 4-hydroxylase	0	2	0	2
Alpha-ketoglutarate-dependent dioxygenase FTO	0	2	0	2
Chain B, EUKARYOTIC TRANSLATION INITIATION FACTOR 4E	0	0	1	1
Heme oxygenase 1	0	2	0	2
Heme oxygenase 2	0	2	0	2
Ricin	0	1	0	1
2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase	0	0	1	1
Purine nucleoside phosphorylase	0	0	1	2
Guanine deaminase	0	1	0	2
transient receptor potential cation channel subfamily V member 1	1	0	0	1
Voltage-dependent L-type calcium channel subunit alpha-1C	0	3	0	3
UDP-glucuronosyltransferase 1A9	0	1	0	3
Vitamin D-binding protein	0	1	0	1
HLA class I histocompatibility antigen, A alpha chain	0	1	1	2
Integrin beta-1	0	1	0	1
Beta-2 adrenergic receptor	0	4	0	5
Integrin alpha-4	0	1	0	1
Carbonyl reductase [NADPH] 1	0	0	0	1
Beta-1 adrenergic receptor	0	3	1	5
5-hydroxytryptamine receptor 3A	0	1	0	1
Beta-3 adrenergic receptor	0	3	0	3
C-8 sterol isomerase	0	2	0	2
Delta-type opioid receptor	0	4	1	5
Mu-type opioid receptor	0	4	1	5
5-hydroxytryptamine receptor 2C	0	1	0	1
Kappa-type opioid receptor	0	4	1	5
Alpha-1A adrenergic receptor	0	3	2	6
5-hydroxytryptamine receptor 2A	0	1	0	1
Alpha-1B adrenergic receptor	0	3	1	5
Kappa-type opioid receptor	0	3	0	4
5-hydroxytryptamine receptor 2A	0	1	0	1
D(2) dopamine receptor	0	1	0	1
D(3) dopamine receptor	0	1	0	1
AP-2 complex subunit sigma	0	1	0	1
N-acetyltransferase Eis	0	2	0	2
5-hydroxytryptamine receptor 2B	0	1	0	1
5-hydroxytryptamine receptor 4	0	1	0	1
3-beta-hydroxysteroid-Delta(8),Delta(7)-isomerase	0	2	0	2
Calcitonin gene-related peptide type 1 receptor	0	1	0	1
Genome polyprotein	0	2	0	2
Sigma intracellular receptor 2	0	1	0	1
Sigma intracellular receptor 2	0	2	0	2
Zinc finger protein 664	0	1	0	1
Vesicular acetylcholine transporter	0	1	0	1
Transporter	0	2	0	2
Cholecystokinin receptor type A	0	1	0	1
Protease	0	4	1	7
Transient receptor potential cation channel subfamily V member 4	0	1	0	1
Chain A, CARBONIC ANHYDRASE II	0	0	1	1
Chain A, Protein (female-specific Histamine Binding Protein 2)	0	0	1	1
aryl hydrocarbon receptor nuclear translocator	0	0	0	1
transforming acidic coiled-coil-containing protein 3	0	0	0	1
Carbonic anhydrase 3	0	3	0	8
Macrophage migration inhibitory factor	0	3	0	3
Carbonic anhydrase 6	0	3	0	8
Carbonic anhydrase 5A, mitochondrial	0	5	0	10
Carbonic anhydrase 7	0	3	0	8
Carbonic anhydrase	0	0	0	6
Histamine H3 receptor	0	1	0	1
Histamine N-methyltransferase	0	1	0	1
Glutaminyl-peptide cyclotransferase	0	2	0	2
Carbonic anhydrase	0	0	0	6
Carbonic anhydrase	0	0	0	6
Carbonic anhydrase	0	0	0	6
Carbonic anhydrase	0	0	0	6
Equilibrative nucleoside transporter 4	0	0	0	1
Carbonic anhydrase 13	0	0	0	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	2	3
Histamine H4 receptor	0	1	0	1
Carbonic anhydrase 13	0	3	0	8
Carboxylic ester hydrolase	0	0	0	1
Carbonic anhydrase 14	0	3	0	8
Carbonic anhydrase 5B, mitochondrial	0	3	0	8
Chain A, HISTIDINE-BINDING PROTEIN	0	0	1	1
Histidine-binding periplasmic protein	0	0	1	1
Large neutral amino acids transporter small subunit 1	0	6	0	7
Neutral amino acid transporter A	0	1	0	1
Asc-type amino acid transporter 1	0	1	0	1
Neutral amino acid transporter B(0)	0	1	0	1
Amino acid transporter	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	3	0	3
Gamma-aminobutyric acid receptor subunit delta	0	3	0	3
Stromelysin-1	0	2	2	4
Gamma-aminobutyric acid receptor subunit alpha-1	0	3	0	3
Urease subunit alpha	0	2	0	2
Gamma-aminobutyric acid receptor subunit beta-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-2	0	3	0	3
Ribonucleoside-diphosphate reductase large subunit	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-5	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit beta-2	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-4	0	3	0	3
Urease subunit beta	0	2	0	2
Gamma-aminobutyric acid receptor subunit epsilon	0	3	0	3
Gamma-aminobutyric acid receptor subunit alpha-6	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-1	0	3	0	3
Gamma-aminobutyric acid receptor subunit gamma-3	0	3	0	3
Gamma-aminobutyric acid receptor subunit theta	0	3	0	3
Acetylcholinesterase	0	3	0	3
Nuclear factor NF-kappa-B p105 subunit	0	1	0	1
Genome polyprotein	0	1	0	1
Amine oxidase [flavin-containing] B	0	4	0	4
Testosterone 17-beta-dehydrogenase 3	0	1	0	1
Small conductance calcium-activated potassium channel protein 3	0	1	0	1
Cholinesterase	0	2	0	2
Sorbitol dehydrogenase	0	1	0	1
Induced myeloid leukemia cell differentiation protein Mcl-1	0	2	0	2
Oleandomycin glycosyltransferase	0	0	0	1
DNA repair protein RAD52 homolog isoform a	0	0	0	2
Tyrosine-protein kinase ABL1	0	3	5	8
Mast/stem cell growth factor receptor Kit	0	2	2	4
Breakpoint cluster region protein	0	2	4	6
Platelet-derived growth factor receptor alpha	0	2	2	4
Cytochrome P450 3A5	0	1	0	2
7,8-dihydro-8-oxoguanine triphosphatase	0	1	0	1
Toll-like receptor 8	0	0	1	1
Toll-like receptor 7	0	0	1	1
Chain A, membrane-associated prostaglandin E synthase-2	0	1	0	1
Parkin	6	0	0	6
Prostaglandin E synthase	0	1	0	1
3',5'-cyclic-AMP phosphodiesterase	0	1	0	1
Cytochrome c oxidase subunit 2	0	1	0	1
Phospholipase A2, major isoenzyme	0	1	0	1
Interleukin-8	0	1	0	1
Polyunsaturated fatty acid 5-lipoxygenase	0	2	0	3
Aldo-keto reductase family 1 member B1	0	2	0	2
Aldo-keto reductase family 1 member C4	0	1	0	1
Prostaglandin G/H synthase 1	0	1	0	1
Sodium- and chloride-dependent GABA transporter 1	0	1	0	1
Serum paraoxonase/arylesterase 1	0	1	0	1
Indoleamine 2,3-dioxygenase 1	0	5	0	5
Caspase-1	0	0	0	1
Prostaglandin E2 receptor EP3 subtype	0	1	0	1
Sodium- and chloride-dependent GABA transporter 2	0	1	0	1
Sodium- and chloride-dependent GABA transporter 3	0	1	0	1
Prostaglandin E2 receptor EP4 subtype	0	1	0	1
Multidrug resistance-associated protein 1	0	1	0	2
Bifunctional epoxide hydrolase 2	0	2	0	2
Prostaglandin G/H synthase 2	0	2	0	2
Prostaglandin E2 receptor EP1 subtype	0	1	0	1
Aldo-keto reductase family 1 member C3	0	2	0	2
Sodium- and chloride-dependent betaine transporter	0	1	0	1
C-X-C chemokine receptor type 3	0	1	0	1
Aldo-keto reductase family 1 member C2	0	1	0	1
Prostaglandin D2 receptor	0	2	0	2
Aldo-keto reductase family 1 member C1	0	1	0	1
Prostaglandin G/H synthase 2	0	1	0	2
Uracil nucleotide/cysteinyl leukotriene receptor	0	2	0	2
Solute carrier family 22 member 7	0	1	0	3
Prostaglandin E2 receptor EP2 subtype	0	1	0	1
Prostaglandin G/H synthase 1	0	2	0	2
Dehydrogenase/reductase SDR family member 9	0	1	0	1
P2Y purinoceptor 12	0	1	0	1
Prostaglandin D2 receptor 2	0	1	1	2
Chain B, Pulmonary surfactant-associated protein D	0	1	0	1
Chain A, Pulmonary surfactant-associated protein D	0	1	0	1
Amyloid-beta precursor protein	0	5	0	5
Sodium/myo-inositol cotransporter 2	0	1	0	1
3-oxoacyl-[acyl-carrier-protein] synthase 3	0	1	0	1
N-glycosylase/DNA lyase	0	1	0	1
Formamidopyrimidine-DNA glycosylase	0	1	0	1
DNA gyrase subunit A	0	1	0	1
DNA gyrase subunit B	0	1	0	1
Cytochrome P450 2A6	0	2	0	2
Endonuclease III-like protein 1	0	1	0	1
DNA gyrase subunit B	0	1	0	1
DNA gyrase subunit A	0	1	0	1
Enoyl-[acyl-carrier-protein] reductase [NADH]	0	1	0	2
Pantothenate synthetase	0	1	0	1
Isocitrate lyase	0	1	0	1
Putative FAD-containing monooxygenase MymA	0	1	0	1
Dihydrofolate reductase	0	2	0	2
Endonuclease 8-like 1	0	1	0	1
Ornithine decarboxylase	0	0	0	2
Retinoic acid receptor alpha	0	2	2	4
Retinoic acid receptor gamma	0	2	2	4
Retinoic acid receptor beta	0	2	2	4
Cellular retinoic acid-binding protein 2	0	0	2	2
Mitogen-activated protein kinase 1	0	4	3	7
Cellular retinoic acid-binding protein 1	0	2	0	3
Cellular retinoic acid-binding protein 1	0	0	2	2
Rap guanine nucleotide exchange factor 4	4	0	0	4
Chymotrypsinogen A	0	3	0	3
Cytochrome P450 1A1	0	2	0	2
Cytochrome P450 1B1	0	1	0	1
Tyrosinase	0	1	1	2
D-amino-acid oxidase	0	1	0	1
Polymerase acidic protein	0	1	1	2
Tyrosinase	0	2	0	2
D-amino-acid oxidase	0	2	0	2
Uncharacterized protein YOR062C	0	1	0	1
Polyphenol oxidase 1	0	2	0	2
Tyrosinase	0	1	0	1
Alpha-crystallin B chain	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	0	1
14-alpha sterol demethylase	0	0	0	1
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, AMINOPEPTIDASE	0	2	0	2
Chain A, Leucine Aminopeptidase	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	5	0	5
Intestinal-type alkaline phosphatase	0	4	0	4
Phospholipase A-2-activating protein	0	4	0	4
Gonadotropin-releasing hormone receptor	0	1	0	1
Gonadotropin-releasing hormone receptor	0	2	0	2
WRN	1	0	0	1
integrase, partial	0	2	0	2
lens epithelium-derived growth factor p75	0	2	0	2
pyruvate kinase	1	0	0	1
hexokinase-4 isoform 1	1	0	0	1
glucokinase regulatory protein	1	0	0	1
SLC16A10 protein	0	0	0	3
Monocarboxylate transporter 10	0	0	0	3
phosphoglycerate kinase	2	0	0	2
Neprilysin	0	1	0	1
Atrial natriuretic peptide receptor 3	0	1	0	1
Thromboxane A2 receptor	0	1	0	2
Type-1A angiotensin II receptor	0	2	1	3
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	4	0	4
Type-1B angiotensin II receptor	0	2	0	2
Type-1 angiotensin II receptor	0	3	2	7
Type-2 angiotensin II receptor	0	2	0	2
Squalene synthase	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	4	0	4
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	4	0	4
cGMP-inhibited 3',5'-cyclic phosphodiesterase B	0	2	0	2
cGMP-inhibited 3',5'-cyclic phosphodiesterase A	0	2	0	2
Platelet glycoprotein VI	0	1	1	3
Type-1 angiotensin II receptor	0	1	1	2
Chain A, Antigen Cd11a (p180)	0	1	0	1
PINK1	3	0	0	3
isocitrate dehydrogenase 1, partial	2	0	0	2
bcl-2-related protein A1	0	1	0	1
Integrin beta-2	0	1	0	1
Intercellular adhesion molecule 1	0	1	0	1
Neutrophil elastase	0	1	0	1
Integrin alpha-L	0	1	1	2
Acyl-CoA:cholesterol acyltransferase	0	1	0	1
Gastrin/cholecystokinin type B receptor	0	1	0	1
Large neutral amino acids transporter small subunit 1	0	2	0	2
UDP-glucose 6-dehydrogenase	0	1	0	1
Solute carrier family 22 member 8	0	0	0	1
UDP-glucose 6-dehydrogenase	0	1	0	1
UDP-glucuronosyltransferase 1A1	0	1	0	1
Dihydrofolate reductase	0	6	0	7
Dipeptidyl peptidase 4	0	2	0	2
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
Chain B, DIHYDROFOLATE REDUCTASE	0	0	1	1
ClpP	1	0	0	1
Thymidylate synthase	0	1	0	1
Thymidylate synthase	0	1	0	1
polyunsaturated fatty acid lipoxygenase ALOX12	2	0	0	2
Toll-like receptor 4	0	1	0	1
Fatty-acid amide hydrolase 1	0	1	0	1
ATP-binding cassette sub-family C member 3	0	1	0	3
Dihydrofolate reductase	0	2	0	3
Dihydrofolate reductase	0	2	0	2
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	2	0	3
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
High mobility group protein B1	0	0	2	2
Dihydrofolate reductase	0	1	0	1
Thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Folate receptor beta	0	1	0	1
Cytochrome P450 11B1, mitochondrial	0	1	0	1
Folate receptor alpha	0	1	0	1
Histidine decarboxylase	0	1	1	2
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Bifunctional purine biosynthesis protein ATIC	0	2	0	2
Reduced folate transporter	0	2	0	2
6-phosphogluconate dehydrogenase, decarboxylating	0	1	0	1
Pteridine reductase 1	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Bifunctional dihydrofolate reductase-thymidylate synthase	0	1	0	1
Canalicular multispecific organic anion transporter 1	0	2	0	4
Trifunctional purine biosynthetic protein adenosine-3	0	1	0	1
Dihydrofolate reductase	0	1	0	1
Dihydrofolate reductase	0	1	0	1
ATP-binding cassette sub-family C member 11	0	0	0	1
Proton-coupled folate transporter	0	1	0	1
Chain E, Fibrin beta chain	0	1	0	1
T cell receptor, partial	1	0	0	1
luteinizing hormone receptor	1	0	0	1
chaperonin-containing TCP-1 beta subunit homolog	2	0	0	2
Caspase 6, apoptosis-related cysteine peptidase	0	0	0	1
TSHR protein	1	0	0	1
Apoptotic peptidase activating factor 1	0	1	0	1
neutrophil cytosol factor 1	0	1	0	1
caspase-9 isoform alpha precursor	0	1	0	1
pyruvate kinase PKM isoform a	1	0	0	1
caspase-3 isoform a preproprotein	0	1	0	1
protein AF-9 isoform a	0	0	0	1
replicative DNA helicase	0	0	0	1
recombinase A	0	0	1	1
POsterior Segregation	0	0	1	1
Glutathione reductase	0	1	0	1
Glycoprotein hormones alpha chain	1	0	0	1
Dihydrolipoyl dehydrogenase, mitochondrial	0	1	0	2
Microtubule-associated protein tau	0	3	1	4
Amine oxidase [flavin-containing] A	0	4	0	4
Thioredoxin reductase 1, cytoplasmic	0	1	0	2
Dihydrolipoyl dehydrogenase	0	1	0	2
Zinc finger protein mex-5	0	0	1	1
Nuclear receptor subfamily 1 group I member 2	0	0	1	1
Potassium channel subfamily K member 9	0	1	0	1
heat shock protein HSP 90-alpha isoform 2	0	0	0	2
Cytochrome P450 1A2	0	1	0	1
Cytochrome P450 1A2	0	1	0	1
Steroid 17-alpha-hydroxylase/17,20 lyase	0	1	0	1
Epoxide hydrolase 1	0	0	0	1
Indoleamine 2,3-dioxygenase 1	0	3	0	4
Cannabinoid receptor 1	0	4	0	4
Aromatase	0	0	1	1
Substance-P receptor	0	2	0	2
Malate dehydrogenase, cytoplasmic	0	1	0	1
Beta-lactamase TEM	0	1	0	1
Mycocyclosin synthase	0	0	1	1
Lanosterol 14-alpha demethylase	0	0	1	1
Indoleamine 2,3-dioxygenase 2	0	4	0	4
heat shock protein 90, putative	0	0	0	2
methionyl-tRNA synthetase, putative	0	1	0	1
Matrilysin	0	1	0	1
Multidrug transporter MdfA	0	1	0	1
Matrix metalloproteinase-9	0	1	0	1
Chain A, Isoleucyl-tRNA synthetase	0	1	0	1
heat shock protein 90	0	0	1	1
streptokinase A precursor	0	0	1	1
twin arginine protein translocation system - TatA protein	0	0	0	1
Isoleucine--tRNA ligase	0	1	0	1
Estrogen receptor	0	0	2	2
L-cysteine:1D-myo-inositol 2-amino-2-deoxy-alpha-D-glucopyranoside ligase	0	1	0	1
Estrogen receptor beta	0	0	2	2
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
Chain B, Exotoxin A	0	0	1	1
5-hydroxytryptamine receptor 3E	0	2	0	2
5-hydroxytryptamine receptor 3B	0	2	0	2
Kappa-type opioid receptor	0	2	1	3
Nociceptin receptor	0	1	0	1
Mu-type opioid receptor	0	2	1	4
5-hydroxytryptamine receptor 3A	0	2	0	2
Mu-type opioid receptor	0	2	1	4
5-hydroxytryptamine receptor 3D	0	2	0	2
5-hydroxytryptamine receptor 3C	0	2	0	2
UDP-glucuronosyltransferase 1A8	0	0	0	1
Cholesteryl ester transfer protein	0	1	0	1
Hydroxycarboxylic acid receptor 3	0	0	1	1
Nicotinamidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	0	1	1
D-aspartate oxidase	0	1	0	1
Hydroxycarboxylic acid receptor 2	0	1	1	2
Sodium/iodide cotransporter	0	1	0	1
Progesterone receptor	0	4	2	7
Transporter	0	1	0	1
Chain A, Adipocyte Lipid-binding Protein	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, MUSCLE FATTY ACID BINDING PROTEIN	0	0	1	1
Chain A, BCL-2-RELATED PROTEIN A1	0	0	1	1
putative potassium channel subunit	0	0	1	1
bcl-2-like protein 11 isoform 1	0	0	1	1
Sterol O-acyltransferase 1	0	2	0	2
DNA topoisomerase 1	0	1	0	1
Protein kinase C alpha type	0	0	3	4
Sterol O-acyltransferase 1	0	2	0	2
BRCA1	1	0	0	1
Chain A, Fatty acid-binding protein, adipocyte	0	1	0	1
Toll-like receptor 2	0	1	0	1
N(G),N(G)-dimethylarginine dimethylaminohydrolase 1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-1	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-2	0	1	0	1
Fatty acid synthase	0	2	0	2
Sodium/potassium-transporting ATPase subunit alpha-2	0	1	0	1
Sodium/potassium-transporting ATPase subunit beta-3	0	1	0	1
Sodium/potassium-transporting ATPase subunit gamma	0	1	0	1
Sodium/potassium-transporting ATPase subunit alpha-4	0	1	0	1
Type II pantothenate kinase	0	0	0	1
Type III pantothenate kinase	0	0	0	1
interferon gamma precursor	0	0	0	1
Somatostatin receptor type 1	0	1	0	1
Somatostatin receptor type 2	0	1	0	1
Somatostatin receptor type 4	0	1	0	1
Somatostatin receptor type 3	0	1	0	1
Somatostatin receptor type 5	0	1	0	1
Cystathionine gamma-lyase	0	2	0	2
Succinyl-diaminopimelate desuccinylase	0	1	0	1
Cytochrome P450 2D26	0	1	0	1
Cytochrome P450 2D3	0	1	0	1
Cytochrome P450 2D4	0	1	0	1
rac GTPase-activating protein 1 isoform a	0	1	0	1
Voltage-dependent calcium channel subunit alpha-2/delta-1	0	1	0	1
Alkaline phosphatase, tissue-nonspecific isozyme	0	1	0	1
Intestinal-type alkaline phosphatase	0	1	0	1
5'-nucleotidase	0	1	0	1
E3 ubiquitin-protein ligase XIAP	0	1	0	1
mu-type opioid receptor isoform MOR-1	0	0	1	1
5-hydroxytryptamine receptor 2A	0	0	1	1
Gamma-aminobutyric acid	0	1	0	1
Sodium channel protein type 2 subunit alpha	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-6	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit delta	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-2	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-1	0	1	0	1
Gamma-aminobutyric acid receptor subunit beta-3	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-5	0	1	0	1
Gamma-aminobutyric acid receptor subunit pi	0	1	0	1
Gamma-aminobutyric acid receptor subunit alpha-4	0	1	0	1
Gamma-aminobutyric acid receptor subunit theta	0	1	0	1
Gamma-aminobutyric acid receptor subunit gamma-1	0	1	0	1
Muscarinic acetylcholine receptor M1	0	1	0	1
Muscarinic acetylcholine receptor DM1	0	1	0	1
Muscarinic acetylcholine receptor M4	0	1	0	1
Muscarinic acetylcholine receptor	0	1	0	1
Muscarinic acetylcholine receptor M5	0	1	0	1
Muscarinic acetylcholine receptor M3	0	1	0	1
Muscarinic acetylcholine receptor M2	0	1	0	1
Chain A, AKAP9-BRAF fusion protein	0	1	0	1
tyrosine-protein kinase Yes	1	0	0	1
Bone morphogenetic protein receptor type-1B	0	0	3	3
Membrane-associated progesterone receptor component 1	0	0	3	3
Serine/threonine-protein kinase PLK4	0	0	3	3
ATP-dependent RNA helicase DDX3X	0	0	3	3
Pirin	0	1	0	1
Pyridoxal kinase	0	0	3	4
Citron Rho-interacting kinase	0	0	3	3
Serine/threonine-protein kinase Chk1	0	0	3	3
Aurora kinase A	0	0	3	3
Cyclin-G-associated kinase	0	0	3	3
Ephrin type-B receptor 6	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 3	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 2	0	0	3	3
Mitotic checkpoint serine/threonine-protein kinase BUB1	0	0	3	3
Dynamin-like 120 kDa protein, mitochondrial	0	0	3	3
Tyrosine-protein kinase JAK2	0	0	3	3
Rho-associated protein kinase 2	0	0	3	3
Serine/threonine-protein kinase ULK1	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE1	0	0	3	3
Ribosomal protein S6 kinase alpha-5	0	0	3	3
U5 small nuclear ribonucleoprotein 200 kDa helicase	0	0	3	3
Ribosomal protein S6 kinase alpha-4	0	0	3	3
Serine/threonine-protein kinase 16	0	0	3	3
Serine/threonine-protein kinase 10	0	0	3	3
Serine/threonine-protein kinase D3	0	0	3	3
Structural maintenance of chromosomes protein 2	0	0	3	3
Mitogen-activated protein kinase kinase kinase 6	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	0	0	3	3
Serine/threonine-protein kinase LATS1	0	0	3	3
Serine/threonine-protein kinase PAK 4	0	0	3	3
GTPase KRas	0	1	0	1
RAF proto-oncogene serine/threonine-protein kinase	0	2	2	5
High affinity nerve growth factor receptor	0	0	3	3
Guanine nucleotide-binding protein G(i) subunit alpha-2	0	0	2	2
ADP/ATP translocase 2	0	0	3	3
Protein kinase C beta type	0	0	3	3
Insulin receptor	0	0	3	3
Glycogen phosphorylase, liver form	0	0	3	3
Tyrosine-protein kinase Fes/Fps	0	0	3	3
Adenine phosphoribosyltransferase	0	0	2	2
Tyrosine-protein kinase Yes	0	0	3	3
Tyrosine-protein kinase Lyn	0	1	3	4
Proto-oncogene tyrosine-protein kinase receptor Ret	0	0	3	3
Insulin-like growth factor 1 receptor	0	0	3	3
Cytochrome c1, heme protein, mitochondrial	0	0	3	3
Hepatocyte growth factor receptor	0	0	3	3
Tyrosine-protein kinase HCK	0	1	3	4
Platelet-derived growth factor receptor beta	0	1	3	4
Tyrosine-protein kinase Fgr	0	0	3	3
Serine/threonine-protein kinase A-Raf	0	1	3	4
Glycogen phosphorylase, brain form	0	0	3	3
Fibroblast growth factor receptor 1	0	0	3	3
DNA topoisomerase 2-alpha	0	0	3	3
Cyclin-dependent kinase 4	0	0	3	3
ADP/ATP translocase 3	0	0	3	3
Inosine-5'-monophosphate dehydrogenase 2	0	0	3	3
Proto-oncogene tyrosine-protein kinase Src	0	2	3	5
cAMP-dependent protein kinase type II-alpha regulatory subunit	0	0	3	3
Serine/threonine-protein kinase B-raf	0	1	4	6
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	0	0	3	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	0	1	3	4
Tyrosine-protein kinase Fer	0	0	3	3
cAMP-dependent protein kinase catalytic subunit alpha	0	0	3	3
General transcription and DNA repair factor IIH helicase subunit XPD	0	0	3	3
Casein kinase II subunit alpha'	0	0	3	3
Ras-related protein Rab-6A	0	0	3	3
Ephrin type-A receptor 1	0	0	3	3
Multifunctional protein ADE2	0	0	3	3
cAMP-dependent protein kinase catalytic subunit beta	0	0	3	3
Ferrochelatase, mitochondrial	0	0	4	4
Ribosomal protein S6 kinase beta-1	0	0	3	3
Tyrosine-protein kinase JAK1	0	0	3	3
Beta-adrenergic receptor kinase 1	0	0	3	3
Probable ATP-dependent RNA helicase DDX6	0	0	3	3
Mitogen-activated protein kinase 3	0	0	3	3
MAP/microtubule affinity-regulating kinase 3	0	0	3	3
Serine/threonine-protein kinase B-raf	0	1	0	1
Ephrin type-A receptor 2	0	1	3	4
Ephrin type-B receptor 2	0	0	3	3
Non-receptor tyrosine-protein kinase TYK2	0	0	3	3
UMP-CMP kinase	0	0	3	3
Phosphatidylethanolamine-binding protein 1	0	0	3	3
Wee1-like protein kinase	0	0	3	3
Heme oxygenase 2	0	0	3	3
S-adenosylmethionine synthase isoform type-2	0	0	3	3
DnaJ homolog subfamily A member 1	0	0	3	3
RAC-alpha serine/threonine-protein kinase	0	0	3	3
RAC-beta serine/threonine-protein kinase	0	0	3	3
DNA replication licensing factor MCM4	0	0	3	3
Myosin-10	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 2	0	2	3	5
Receptor-type tyrosine-protein kinase FLT3	0	1	3	4
Bone morphogenetic protein receptor type-1A	0	0	3	3
Activin receptor type-1B	0	0	3	3
TGF-beta receptor type-1	0	0	3	3
TGF-beta receptor type-2	0	0	3	3
Electron transfer flavoprotein subunit beta	0	0	2	2
Tyrosine-protein kinase CSK	0	0	3	3
Glycine--tRNA ligase	0	0	3	3
Protein kinase C iota type	0	0	3	3
Exosome RNA helicase MTR4	0	0	3	3
Tyrosine-protein kinase Tec	0	0	3	3
Tyrosine-protein kinase ABL2	0	0	3	3
Tyrosine-protein kinase FRK	0	0	3	3
G protein-coupled receptor kinase 6	0	0	3	3
Tyrosine-protein kinase SYK	0	0	3	3
26S proteasome regulatory subunit 6B	0	0	3	3
Mitogen-activated protein kinase 8	0	0	3	3
Mitogen-activated protein kinase 9	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 4	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 alpha	0	0	3	3
Casein kinase I isoform alpha	0	0	3	3
Casein kinase I isoform delta	0	0	3	3
MAP kinase-activated protein kinase 2	0	0	3	3
Elongation factor Tu, mitochondrial	0	0	3	3
Cysteine--tRNA ligase, cytoplasmic	0	0	3	3
Casein kinase I isoform epsilon	0	0	3	3
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	0	0	3	3
Dual specificity protein kinase CLK1	0	0	3	3
Dual specificity protein kinase CLK2	0	0	3	3
Glycogen synthase kinase-3 alpha	0	0	3	3
Glycogen synthase kinase-3 beta	0	0	3	3
Cyclin-dependent kinase 7	0	0	3	3
Cyclin-dependent kinase 9	0	0	3	3
Ras-related protein Rab-27A	0	0	3	3
Interleukin-1 receptor-associated kinase 1	0	0	3	3
Ribosomal protein S6 kinase alpha-3	0	0	3	3
Serine/threonine-protein kinase Nek2	0	0	3	3
Serine/threonine-protein kinase Nek3	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 6	0	0	3	3
Serine/threonine-protein kinase PLK1	0	0	3	3
LIM domain kinase 1	0	0	3	3
LIM domain kinase 2	0	0	3	3
Mitogen-activated protein kinase 10	0	1	3	4
Tyrosine--tRNA ligase, cytoplasmic	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-1	0	0	3	4
Ephrin type-B receptor 3	0	0	3	3
Ephrin type-A receptor 5	0	0	3	3
Ephrin type-B receptor 4	0	0	3	3
Ephrin type-A receptor 4	0	0	3	3
Adenylate kinase 2, mitochondrial	0	0	3	3
Adenosine kinase	0	0	3	3
Ras-related protein Rab-10	0	0	3	3
Actin-related protein 3	0	0	3	3
Actin-related protein 2	0	0	3	3
GTP-binding nuclear protein Ran	0	0	3	3
Casein kinase I isoform gamma-2	0	0	3	3
Cyclin-dependent kinase 3	0	0	3	3
Cyclin-dependent kinase 6	0	0	3	3
Cyclin-dependent-like kinase 5	0	0	3	3
Cyclin-dependent kinase 16	0	0	3	3
Cyclin-dependent kinase 17	0	0	3	3
Heat shock factor protein 1	0	1	0	1
ATP-dependent 6-phosphofructokinase, platelet type	0	0	3	3
Dual specificity mitogen-activated protein kinase kinase 1	0	2	3	5
DNA topoisomerase 2-beta	0	0	3	3
Protein kinase C theta type	0	0	3	3
Activin receptor type-1	0	0	3	3
Macrophage-stimulating protein receptor	0	0	3	3
Focal adhesion kinase 1	0	0	3	3
Protein kinase C delta type	0	0	3	3
Tyrosine-protein kinase BTK	0	0	3	3
Activated CDC42 kinase 1	0	0	3	3
Epithelial discoidin domain-containing receptor 1	0	2	3	5
Aspartyl/asparaginyl beta-hydroxylase	0	1	0	1
Mitogen-activated protein kinase kinase kinase kinase 2	0	0	3	3
Tyrosine-protein kinase Mer	0	0	2	2
Serine/threonine-protein kinase 4	0	0	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-1	0	0	3	4
Dual specificity mitogen-activated protein kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase 7	0	0	3	3
Serine/threonine-protein kinase PAK 2	0	0	3	3
Serine/threonine-protein kinase 3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 1	0	0	3	3
Integrin-linked protein kinase	0	0	3	3
Rho-associated protein kinase 1	0	0	3	3
Non-receptor tyrosine-protein kinase TNK1	0	0	3	3
Serine/threonine-protein kinase ATR	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit gamma	0	0	3	3
Calcium/calmodulin-dependent protein kinase type II subunit delta	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	0	0	3	3
Activin receptor type-2B	0	0	3	3
Bone morphogenetic protein receptor type-2	0	0	3	3
Protein-tyrosine kinase 6	0	0	3	3
cGMP-dependent protein kinase 1	0	0	3	3
Cyclin-dependent kinase 13	0	0	3	3
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	0	0	3	3
Protein-tyrosine kinase 2-beta	0	0	3	3
Maternal embryonic leucine zipper kinase	0	0	3	3
Structural maintenance of chromosomes protein 1A	0	0	3	3
Chromodomain-helicase-DNA-binding protein 4	0	0	3	3
Peroxisomal acyl-coenzyme A oxidase 1	0	0	2	2
Cyclin-dependent kinase 10	0	0	2	2
Delta(24)-sterol reductase	0	0	3	3
Ribosomal protein S6 kinase alpha-1	0	0	3	3
Myosin light chain kinase, smooth muscle	0	0	3	3
Serine/threonine-protein kinase STK11	0	0	3	3
Serine/threonine-protein kinase N1	0	0	3	3
Serine/threonine-protein kinase N2	0	0	3	3
Calcium/calmodulin-dependent protein kinase type IV	0	0	3	3
Mitogen-activated protein kinase kinase kinase 11	0	0	3	3
Discoidin domain-containing receptor 2	0	2	3	5
AP2-associated protein kinase 1	0	0	3	3
Myosin light chain kinase 3	0	0	3	3
Uncharacterized aarF domain-containing protein kinase 5	0	0	2	2
Putative heat shock protein HSP 90-beta 2	0	0	3	3
Rab-like protein 3	0	0	3	3
Serine/threonine-protein kinase MRCK alpha	0	0	3	3
Serine/threonine-protein kinase MRCK gamma	0	0	3	3
Acyl-CoA dehydrogenase family member 10	0	0	3	3
Serine/threonine-protein kinase N3	0	0	3	3
Serine/threonine-protein kinase ULK3	0	0	3	3
Uncharacterized protein FLJ45252	0	0	3	3
Acyl-CoA dehydrogenase family member 11	0	0	3	3
Serine/threonine-protein kinase/endoribonuclease IRE2	0	0	3	3
Serine/threonine-protein kinase MARK2	0	0	3	3
Serine/threonine-protein kinase TAO1	0	0	3	3
STE20-related kinase adapter protein alpha	0	0	3	3
Myosin-14	0	0	3	3
AarF domain-containing protein kinase 1	0	0	3	3
ATP-dependent RNA helicase DDX42	0	0	2	2
Mitogen-activated protein kinase kinase kinase kinase 3	0	0	3	3
MAP kinase-activated protein kinase 5	0	0	3	3
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	0	0	2	2
Atypical kinase COQ8A, mitochondrial	0	0	3	3
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	0	0	3	3
Mitogen-activated protein kinase 15	0	0	3	3
Serine/threonine-protein kinase Nek9	0	0	3	3
Serine/threonine-protein kinase Nek7	0	0	2	2
ATP-dependent RNA helicase DDX1	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 1	0	0	3	3
MAP/microtubule affinity-regulating kinase 4	0	0	3	3
Serine/threonine-protein kinase Nek1	0	0	3	3
Calcium/calmodulin-dependent protein kinase kinase 2	0	0	3	3
EKC/KEOPS complex subunit TP53RK	0	0	3	3
Dual specificity testis-specific protein kinase 2	0	0	3	3
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	0	0	3	3
Mitogen-activated protein kinase kinase kinase 5	0	0	3	3
Mitogen-activated protein kinase kinase kinase 3	0	0	3	3
Eukaryotic translation initiation factor 2-alpha kinase 1	0	0	3	3
Nucleolar GTP-binding protein 1	0	0	3	3
Serine/threonine-protein kinase D2	0	0	3	3
NUAK family SNF1-like kinase 2	0	0	3	3
RNA cytidine acetyltransferase	0	0	3	3
Serine/threonine-protein kinase SIK2	0	0	3	3
STE20-like serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO3	0	0	3	3
dCTP pyrophosphatase 1	0	0	3	3
Dual specificity protein kinase CLK4	0	0	3	3
Casein kinase I isoform gamma-1	0	0	3	3
Phenylalanine--tRNA ligase beta subunit	0	0	3	3
BMP-2-inducible protein kinase	0	0	3	3
Obg-like ATPase 1	0	0	3	3
Midasin	0	0	3	3
Interleukin-1 receptor-associated kinase 4	0	0	3	3
Mitogen-activated protein kinase kinase kinase 20	0	1	3	4
Cyclin-dependent kinase 12	0	0	3	3
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	0	0	3	3
Serine/threonine-protein kinase pim-2	0	0	3	3
Serine/threonine-protein kinase 26	0	0	3	3
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	0	0	3	3
Serine/threonine-protein kinase NLK	0	0	3	3
5'-AMP-activated protein kinase subunit gamma-2	0	0	3	4
Serine/threonine-protein kinase TBK1	0	0	3	3
Septin-9	0	0	3	3
Ribosomal protein S6 kinase alpha-6	0	0	3	3
TRAF2 and NCK-interacting protein kinase	0	0	3	3
Serine/threonine-protein kinase TAO2	0	0	3	3
Long-chain-fatty-acid--CoA ligase 5	0	0	1	1
Serine/threonine-protein kinase ICK	0	0	3	3
RAC-gamma serine/threonine-protein kinase	0	0	3	3
Serine/threonine-protein kinase 38-like	0	0	2	2
Serine/threonine-protein kinase SIK3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 2	0	0	3	3
Thyroid hormone receptor-associated protein 3	0	0	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	0	0	3	3
Mitogen-activated protein kinase kinase kinase kinase 5	0	0	3	3
Receptor-interacting serine/threonine-protein kinase 3	0	0	3	3
Serine/threonine-protein kinase MRCK beta	0	0	3	3
Interleukin-1 receptor-associated kinase 3	0	0	3	3
Casein kinase I isoform gamma-3	0	0	3	3
Mitogen-activated protein kinase kinase kinase 4	0	0	3	3
Solute carrier organic anion transporter family member 1A4	0	3	0	7
Solute carrier family 22 member 7	0	1	0	1
luciferase	0	0	0	1
Glucocorticoid receptor	0	1	1	2
Glucocorticoid receptor	0	0	1	1
Mineralocorticoid receptor	0	2	1	3
Glutamine synthetase	0	0	1	1
Nociceptin receptor	0	0	1	1
Polyunsaturated fatty acid lipoxygenase ALOX15	0	1	0	1
Vascular cell adhesion protein 1	0	1	0	1
NAD-dependent protein deacylase sirtuin-5, mitochondrial	0	2	0	2
Acetylcholinesterase	0	1	0	1
DNA (cytosine-5)-methyltransferase 1	0	1	0	1
Solute carrier family 22 member 4	0	1	0	1
DNA (cytosine-5)-methyltransferase 3-like	0	1	0	1
DNA (cytosine-5)-methyltransferase 3A	0	1	0	1
Beta-1 adrenergic receptor	0	1	1	3
Beta-2 adrenergic receptor	0	2	1	3
Voltage-dependent L-type calcium channel subunit alpha-1C	0	1	0	1
5-hydroxytryptamine receptor 1B	0	2	1	3
Neuromedin-K receptor	0	0	1	1
Cholecystokinin receptor type A	0	1	1	2
Beta-1 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	0	1
Beta-2 adrenergic receptor	0	1	1	3
Nuclear receptor subfamily 2 group E member 1	0	0	2	2
Monocarboxylate transporter 2	0	0	0	1
Monocarboxylate transporter 1	0	0	0	1
C-terminal-binding protein 2	0	1	0	1
Solute carrier organic anion transporter family member 2A1	0	1	0	1
Chain A, Bacterial regulatory proteins, tetR family	0	0	1	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Chain A, Carbonic anhydrase 2	0	1	0	1
Prolyl 4-hydroxylase subunit alpha-1	0	2	0	2
Carbonic anhydrase	0	2	0	2
Carbonic anhydrase 3	0	1	0	1
Chain A, PLASMA RETINOL-BINDING PROTEIN PRECURSOR	0	0	1	1
Retinol-binding protein 4	0	0	1	1
Beta-lactoglobulin	0	0	1	1
Chain A, HIV-1 PROTEASE	0	1	0	1
Chain B, HIV-1 PROTEASE	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, POL polyprotein	0	1	0	1
Chain B, POL polyprotein	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Chain A, Endothiapepsin	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Gag-Pol polyprotein	0	1	0	1
Thromboxane-A synthase	0	0	0	1
Plasmepsin V	0	1	0	1
Protease	0	2	1	3
Genome polyprotein	0	1	0	1
Neuraminidase	0	2	0	2
glycogen synthase kinase-3 beta isoform 1	0	0	1	1
Lysine-specific histone demethylase 1A	0	1	0	1
L-lactate dehydrogenase A chain	0	1	0	1
Neuraminidase	0	1	0	1
Beta-lactamase	0	1	0	1
Sialidase	0	1	0	1
Cystic fibrosis transmembrane conductance regulator	0	0	1	1
Prolyl endopeptidase	0	1	0	1
Dihydroorotate dehydrogenase	0	1	0	1
Substance-K receptor	0	1	0	1
Neuromedin-U receptor 2	0	0	1	1
Leukotriene C4 synthase	0	0	1	1
Cell division cycle 7-related protein kinase	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	0	0	1	1
Serine/threonine-protein kinase 25	0	0	1	1
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	0	0	1	1
Serine/threonine-protein kinase RIO3	0	0	1	1
Dual specificity mitogen-activated protein kinase kinase 7	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	0	0	1	2
Peripheral plasma membrane protein CASK	0	0	1	1
Serine/threonine-protein kinase DCLK1	0	0	1	1
Inhibitor of nuclear factor kappa-B kinase subunit alpha	0	0	1	1
Muscle, skeletal receptor tyrosine-protein kinase	0	0	1	1
3-phosphoinositide-dependent protein kinase 1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 13	0	0	1	1
Death-associated protein kinase 3	0	0	1	1
Mitogen-activated protein kinase kinase kinase 7	0	0	1	1
NUAK family SNF1-like kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	0	0	1	1
Eukaryotic translation initiation factor 5B	0	0	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	0	0	1	1
Serine/threonine-protein kinase PAK 3	0	0	1	1
Cyclin-dependent kinase-like 5	0	0	2	2
Serine/threonine-protein kinase 17B	0	0	1	1
Cyclin-dependent kinase 14	0	0	1	1
Serine/threonine-protein kinase OSR1	0	0	1	1
Serine/threonine-protein kinase Chk2	0	0	1	1
Proto-oncogene tyrosine-protein kinase Src	0	0	1	1
Low-density lipoprotein receptor	0	1	0	1
Fibronectin	0	1	0	1
Macrophage colony-stimulating factor 1 receptor	0	1	1	2
Signal recognition particle receptor subunit alpha	0	0	2	2
Proto-oncogene tyrosine-protein kinase ROS	0	0	1	1
Macrophage colony-stimulating factor 1 receptor	0	1	0	1
Wee1-like protein kinase 2	0	0	1	1
Uncharacterized serine/threonine-protein kinase SBK3	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 4	0	1	0	1
Insulin receptor-related protein	0	0	1	1
Potassium voltage-gated channel subfamily E member 1	0	1	0	1
Vascular endothelial growth factor receptor 1	0	0	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	0	0	1	1
Serine/threonine-protein kinase MAK	0	0	1	1
Cyclin-dependent kinase 11B	0	0	1	1
Fibroblast growth factor receptor 2	0	0	1	1
Receptor tyrosine-protein kinase erbB-3	0	0	1	1
Fibroblast growth factor receptor 4	0	0	1	1
Fibroblast growth factor receptor 3	0	0	1	1
cAMP-dependent protein kinase catalytic subunit gamma	0	0	2	2
Protein kinase C eta type	0	0	1	1
Activin receptor type-2A	0	0	1	1
Ephrin type-A receptor 3	0	0	1	1
Ephrin type-A receptor 8	0	0	1	1
Leukocyte tyrosine kinase receptor	0	0	1	1
Tyrosine-protein kinase receptor UFO	0	0	1	1
Mitogen-activated protein kinase 4	0	0	1	1
G protein-coupled receptor kinase 4	0	0	1	1
Dual specificity protein kinase TTK	0	0	2	2
Tyrosine-protein kinase receptor Tie-1	0	0	1	1
Vascular endothelial growth factor receptor 3	0	0	1	1
Serine/threonine-protein kinase receptor R3	0	0	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	0	0	1	1
Serine/threonine-protein kinase mTOR	0	0	1	1
Megakaryocyte-associated tyrosine-protein kinase	0	0	1	1
Tyrosine-protein kinase TXK	0	0	1	1
Tyrosine-protein kinase ZAP-70	0	0	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	0	1	1	2
Cyclin-dependent kinase 8	0	0	1	1
Dual specificity protein kinase CLK3	0	0	2	2
Tyrosine-protein kinase Blk	0	1	1	2
Potassium voltage-gated channel subfamily KQT member 1	0	1	0	1
Cytoplasmic tyrosine-protein kinase BMX	0	0	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	0	0	1	1
Serine/threonine-protein kinase Nek4	0	0	1	1
Tyrosine-protein kinase JAK3	0	0	1	1
Death-associated protein kinase 1	0	0	1	1
5'-AMP-activated protein kinase catalytic subunit alpha-2	0	0	1	2
Ephrin type-B receptor 1	0	0	1	1
Hormonally up-regulated neu tumor-associated kinase	0	0	1	1
Serine/threonine-protein kinase SIK1	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 4	0	0	1	1
Cell division control protein 2 homolog	0	0	1	1
Calcium-dependent protein kinase 1	0	0	1	1
Ras-related C3 botulinum toxin substrate 1	0	0	1	1
Casein kinase II subunit alpha	0	0	1	1
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	0	0	1	1
SRSF protein kinase 2	0	0	1	1
Mitogen-activated protein kinase kinase kinase 9	0	0	1	1
Serine/threonine-protein kinase PknB	0	0	1	1
Cyclin-dependent kinase-like 1	0	0	1	1
Protein kinase C epsilon type	0	0	1	1
Angiopoietin-1 receptor	0	0	1	1
Mitogen-activated protein kinase kinase kinase 10	0	0	1	1
Protein kinase C zeta type	0	0	2	2
Tyrosine-protein kinase receptor TYRO3	0	0	1	1
Cyclin-dependent kinase 18	0	0	2	2
Tyrosine-protein kinase ITK/TSK	0	0	1	1
Myotonin-protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 12	0	0	1	1
Serine/threonine-protein kinase PAK 1	0	0	1	1
cGMP-dependent protein kinase 2	0	0	1	1
Serine/threonine-protein kinase PRP4 homolog	0	0	1	1
Receptor-interacting serine/threonine-protein kinase 1	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit beta	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1	0	0	1	1
Serine/threonine-protein kinase D1	0	0	1	1
Serine/threonine-protein kinase 38	0	0	1	1
Receptor tyrosine-protein kinase erbB-4	0	0	1	1
Ribosomal protein S6 kinase alpha-2	0	0	1	1
Ephrin type-A receptor 7	0	0	2	2
Dual specificity testis-specific protein kinase 1	0	0	2	2
Rhodopsin kinase GRK1	0	0	1	1
NT-3 growth factor receptor	0	0	1	1
BDNF/NT-3 growth factors receptor	0	0	1	1
Mitogen-activated protein kinase 6	0	0	1	1
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	0	0	1	1
Serine/threonine-protein kinase SBK1	0	0	1	1
Mitogen-activated protein kinase kinase kinase 19	0	0	1	1
Serine/threonine-protein kinase TNNI3K	0	0	1	1
Serine/threonine-protein kinase Nek5	0	0	1	1
Dual serine/threonine and tyrosine protein kinase	0	0	1	1
Mitogen-activated protein kinase kinase kinase 15	0	0	1	1
ATP-dependent RNA helicase DHX30	0	0	2	2
Serine/threonine-protein kinase tousled-like 2	0	0	1	1
Serine/threonine-protein kinase 32C	0	0	1	1
Serine/threonine-protein kinase pim-3	0	0	1	1
Serine/threonine-protein kinase VRK2	0	0	1	1
Myosin light chain kinase family member 4	0	0	1	1
Homeodomain-interacting protein kinase 1	0	0	1	1
Multidrug resistance-associated protein 1	0	1	0	1
Calcium/calmodulin-dependent protein kinase type 1D	0	0	1	1
Cyclin-dependent kinase-like 3	0	0	1	1
Serine/threonine-protein kinase BRSK2	0	0	1	1
Serine/threonine-protein kinase NIM1	0	0	1	1
Serine/threonine-protein kinase ULK2	0	0	1	1
Misshapen-like kinase 1	0	0	2	2
Serine/threonine-protein kinase DCLK2	0	0	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	0	0	1	1
Casein kinase I isoform alpha-like	0	0	1	1
Proprotein convertase subtilisin/kexin type 9	0	1	0	1
Homeodomain-interacting protein kinase 4	0	0	1	1
Myosin-IIIa	0	0	1	1
Ankyrin repeat and protein kinase domain-containing protein 1	0	0	1	1
Serine/threonine-protein kinase Nek11	0	0	1	1
Serine/threonine-protein kinase BRSK1	0	0	1	1
Serine/threonine-protein kinase 35	0	0	1	1
Rhodopsin kinase GRK7	0	0	1	1
Serine/threonine-protein kinase 32A	0	0	1	1
Myosin-IIIb	0	0	1	1
Dual specificity tyrosine-phosphorylation-regulated kinase 2	0	0	1	1
Cyclin-dependent kinase-like 2	0	0	1	1
Serine/threonine-protein kinase Sgk3	0	0	1	1
Atypical kinase COQ8B, mitochondrial	0	0	1	1
Calcium/calmodulin-dependent protein kinase type 1G	0	0	1	1
Cyclin-dependent kinase 15	0	0	1	1
PAS domain-containing serine/threonine-protein kinase	0	0	2	2
SRSF protein kinase 1	0	0	1	1
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	0	0	1	1
Serine/threonine-protein kinase RIO1	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase RIO2	0	0	1	1
Cyclin-dependent kinase 19	0	0	1	1
Transient receptor potential cation channel subfamily M member 6	0	0	1	1
Testis-specific serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 33	0	0	1	1
Serine/threonine-protein kinase DCLK3	0	0	1	1
Myosin light chain kinase 2, skeletal/cardiac muscle	0	0	1	1
Homeodomain-interacting protein kinase 2	0	0	1	1
Tyrosine-protein kinase Srms	0	0	1	1
Homeodomain-interacting protein kinase 3	0	0	1	1
Serine/threonine-protein kinase PLK3	0	0	1	1
MAP kinase-interacting serine/threonine-protein kinase 2	0	0	1	1
Serine/threonine-protein kinase Nek6	0	0	1	1
Serine/threonine-protein kinase PAK 6	0	0	2	2
SNF-related serine/threonine-protein kinase	0	0	1	1
Serine/threonine-protein kinase LATS2	0	0	1	1
Serine/threonine-protein kinase 36	0	0	1	1
Isoleucine--tRNA ligase, mitochondrial	0	0	2	2
Serine/threonine-protein kinase 32B	0	0	1	1
Serine/threonine-protein kinase PLK2	0	0	1	1
Serine/threonine-protein kinase MARK1	0	0	1	1
Serine/threonine-protein kinase PAK 5	0	0	1	1
eIF-2-alpha kinase GCN2	0	0	1	1
Phosphatidylinositol 4-kinase beta	0	0	1	1
Serine/threonine-protein kinase 17A	0	0	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	0	0	1	1
Ephrin type-A receptor 6	0	0	1	1
Death-associated protein kinase 2	0	0	1	1
Potassium voltage-gated channel subfamily D member 3	0	1	0	1
Serine/threonine-protein kinase tousled-like 1	0	0	1	1
ALK tyrosine kinase receptor	0	0	1	1
SRSF protein kinase 3	0	0	1	1
Cyclin-dependent kinase 11A	0	0	1	1
Aurora kinase C	0	0	1	1
Calcium/calmodulin-dependent protein kinase type II subunit alpha	0	0	1	1
Microtubule-associated serine/threonine-protein kinase 1	0	0	1	1
Serine/threonine-protein kinase 24	0	0	2	2
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, Lysr-type Regulatory Protein	0	0	1	1
Chain A, 146aa long hypothetical transcriptional regulator	0	0	1	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain B, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain C, Anthranilate phosphoribosyltransferase	0	1	0	1
Chain A, Anthranilate phosphoribosyltransferase	0	1	0	1
Anthranilate phosphoribosyltransferase	0	1	0	1
Estrogen receptor beta	0	0	0	1
5'-AMP-activated protein kinase subunit beta-2	0	0	0	1
Tyrosine-protein phosphatase YopH	0	1	0	1
Estrogen receptor	0	0	0	1
Ubiquitin-like domain-containing CTD phosphatase 1	0	1	0	1
5'-AMP-activated protein kinase subunit gamma-3	0	0	0	1
5'-AMP-activated protein kinase subunit beta-1	0	0	0	1
photoreceptor-specific nuclear receptor	0	1	0	1
3-hydroxy-3-methylglutaryl-coenzyme A reductase	0	1	0	1
Squalene monooxygenase	0	0	0	1
DNA polymerase beta	0	1	0	1
Chain A, MALTOPORIN	0	0	1	1
Chain B, MALTOPORIN	0	0	1	1
Squalene synthase	0	1	0	1
Sodium/bile acid cotransporter	0	0	0	1
Solute carrier organic anion transporter family member 1A5	0	0	0	3
Sodium/bile acid cotransporter	0	1	0	2
Solute carrier organic anion transporter family member 1A2	0	0	0	3
Ileal sodium/bile acid cotransporter	0	0	0	1
Ileal sodium/bile acid cotransporter	0	0	0	1
Solute carrier organic anion transporter family member	0	0	0	1
Solute carrier organic anion transporter family member 4A1	0	0	0	2
Solute carrier organic anion transporter family member 2B1	0	0	0	1
Solute carrier organic anion transporter family member 1A1	0	0	0	1
Bile salt export pump	0	0	0	1
Solute carrier organic anion transporter family member 1B2	0	0	0	1
DNA-binding protein Ikaros	0	0	0	1
DNA damage-binding protein 1	0	1	1	2
Chain A, Pyridoxal kinase	0	1	0	1
Chain A, Pyridoxal Kinase	0	1	0	1
Phosphodiesterase	0	2	0	2
cGMP-dependent 3',5'-cyclic phosphodiesterase	0	1	0	1
Renin	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4D	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4C	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4B	0	1	0	1
Adenosine receptor A1	0	2	0	2
Adenosine receptor A3	0	1	0	1
Adenosine receptor A2b	0	1	0	2
Adenosine receptor A2b	0	1	0	2
Vasopressin V2 receptor	0	0	0	1
Adenosine receptor A2a	0	1	0	1
Adenosine receptor A1	0	1	0	1
Adenosine receptor A1	0	1	0	1
cAMP-specific 3',5'-cyclic phosphodiesterase 4A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1B	0	1	0	1
Adenylate cyclase type 1	0	0	0	1
Chitotriosidase-1	0	1	0	1
High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A	0	1	0	1
Calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1C	0	1	0	1
Adenosine receptor A2b	0	0	0	1
Palmitoleoyl-protein carboxylesterase NOTUM	0	0	1	1
Endochitinase B1	0	1	0	1
Thymidine phosphorylase	0	0	0	1
Thymidine phosphorylase	0	0	0	1
Thymidylate kinase	0	1	0	1
Thymidine kinase, cytosolic	0	0	0	2
Thymidine kinase	0	0	0	1
Thymidine kinase	0	1	0	2
Sterol O-acyltransferase 1	0	1	0	1
Thymidine kinase	0	0	0	1
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Chain X, Thyroid hormone receptor beta-1	0	0	2	2
Thyroid hormone receptor alpha	0	2	3	5
Thyroid hormone receptor beta	0	2	3	5
Proliferating cell nuclear antigen	0	2	0	2
Malate dehydrogenase, mitochondrial	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	1	0	2
Monocarboxylate transporter 8	0	0	0	1
Solute carrier organic anion transporter family member 1C1	0	0	0	1
UDP-glucuronosyltransferase 1-6	0	2	0	3
UDP-glucuronosyltransferase 2B10	0	1	0	1
Choline-phosphate cytidylyltransferase A	0	0	1	1
MAP kinase-activated protein kinase 3	0	0	1	1
Chain A, Nuclear Receptor ROR-beta	0	1	0	1
Ornithine decarboxylase	0	0	0	1
Alpha-1A adrenergic receptor	0	1	0	1
Nuclear receptor ROR-alpha	0	1	0	1
Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1	0	2	1	3
Nuclear receptor ROR-beta	0	1	0	1
procathepsin L isoform 1 preproprotein	0	1	0	1
Solute carrier organic anion transporter family member 4C1	0	0	0	1
Amine oxidase [flavin-containing] B	0	1	0	1
Amine oxidase [flavin-containing] A	0	1	0	1
Forkhead box protein M1	0	2	0	2
UDP-glucuronosyltransferase 1A10	0	0	0	1
Chain A, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain K, Trp Rna-binding Attenuation Protein	0	0	1	1
Chain B, tryptophanyl-tRNA synthetase	0	0	1	1
Chain C, Tryptophanyl-tRNA synthetase II	0	0	1	1
Tryptophan 2,3-dioxygenase	0	1	0	2
Tryprostatin B synthase	0	0	0	1
2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Chain A, Glycogen phosphorylase, liver form	0	0	1	1
Solute carrier family 2, facilitated glucose transporter member 9	0	1	1	2
M1-family alanyl aminopeptidase	0	1	0	1
Valacyclovir hydrolase	0	0	0	1
Carbonic anhydrase	0	1	0	1
Chain A, Arginase 1	0	1	0	1
Histone deacetylase 3	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Liver carboxylesterase 1	0	1	0	1
Aldo-keto reductase family 1 member A1	0	1	0	1
Histone deacetylase 4	0	2	0	2
Aldo-keto reductase family 1 member A1	0	1	0	1
Aldo-keto reductase family 1 member B7	0	1	0	1
Histone deacetylase 7	0	2	0	2
Polyamine deacetylase HDAC10	0	2	0	2
Histone deacetylase 11	0	2	0	2
Histone deacetylase 8	0	2	0	2
Histone deacetylase 9	0	2	0	2
Histone deacetylase 5	0	2	0	2
Proprotein convertase subtilisin/kexin type 7	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1-like protein 1	0	1	0	1
Vitamin K epoxide reductase complex subunit 1	0	2	0	2
[prepared from compound, protein, and bioassay information from National Library of Medicine (NLM), extracted Dec-2023]

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (1,207)

Protein Targets (2,013)

Xanthoma

Synonyms(2)

Research Excerpts

Overview

Treatment

Research

Studies (1,207)

Drugs Studied (343)

Protein Targets (2,013)