necroptosis inhibitor

Any substance that inhibits the process of necroptosis (programmed form of necrosis) in organisms.

ChEBI ID: 167704

Members (4)

Member	Definition	Class
ly3009120	A member of the class of pyridopyrimidines that is pyrido[2,3-d]pyrimidine substituted by methylamino, 5-{[(3,3-dimethylbutyl)carbamoyl]amino}-4-fluoro-2-methylphenyl, and methyl groups at positions 2, 6 and 7, respectively. It is a potent pan RAF inhibitor which inhibits BRAF(V600E), BRAF(WT) and CRAF(WT) (IC50 = 5.8, 9.1 and 15 nM, respectively). It also inhibits RAF homo- and heterodimers and exhibits anti-cancer properties.	LY3009120
n-(4-(n-(3-methoxypyrazin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide	A sulfonamide that is a 3-methoxypyrazin-2-yl derivative of (E)-N-(4-(N-(4,6-dimethylpyrimidin-2-yl)sulfamoyl)phenyl)-3-(5-nitrothiophene-2-yl)acrylamide. Necrosulfonamide specifically blocks necrosis downstream of the activation of RIP3 (the receptor-interacting serine-threonine kinase 3), a key signalling molecule in the programmed necrosis (necroptosis) pathway.	necrosulfonamide
quizartinib	A member of the class of phenylureas that is urea in which one of the amino groups has been substituted by a 5-tert-butyl-1,2-oxazol-3-yl group while the other has been substituted by a phenyl group substituted at the para- position by an imidazo[2,1-b][1,3]benzothiazol-2-yl group that, in turn, is substituted at position 7 by a 2-(morpholin-4-yl)ethoxy group.	quizartinib
tak-632	A member of the class of benzothiazoles that is 1,3-benzothiazole substituted by (cyclopropanecarbonyl)amino, 4-fluoro-3-{2-[3-(trifluoromethyl)phenyl]acetamido}phenoxy, and cyano groups at positions 2, 6 and 7, respectively. It is a potent pan-RAF inhibitor with IC50 of 1.4, 2.4 and 8.3 nM for CRAF, BRAF(V600E), BRAF(WT), respectively.	TAK-632

Research

Studies (241)

Timeframe	Studies, Drugs with This Role(%)	All Drugs %
pre-1990	0 (0.00)	18.7374
1990's	0 (0.00)	18.2507
2000's	2 (0.83)	29.6817
2010's	149 (61.83)	24.3611
2020's	90 (37.34)	2.80

Study Types

Publication Type	Studies, Drugs with this Role (%)	All Drugs (%)
Trials	17 (6.80%)	5.53%
Reviews	27 (10.80%)	6.00%
Case Studies	5 (2.00%)	4.05%
Observational	0 (0.00%)	0.25%
Other	201 (80.40%)	84.16%

Protein Targets (487)

Potency Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
cytochrome P450 2C9, partial	Homo sapiens (human)	Potency	0.3379	1	1
cytochrome P450 2D6	Homo sapiens (human)	Potency	2.3919	1	1
G	Vesicular stomatitis virus	Potency	0.3379	1	1
HLA class I histocompatibility antigen, B alpha chain	Homo sapiens (human)	Potency	0.3379	1	1
Inositol hexakisphosphate kinase 1	Homo sapiens (human)	Potency	0.3379	1	2
Interferon beta	Homo sapiens (human)	Potency	0.3379	1	1

Inhibition Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
Angiopoietin-1 receptor	Homo sapiens (human)	IC50	0.7400	1	1
Aurora kinase A	Homo sapiens (human)	IC50	10.0000	2	2
Aurora kinase B	Homo sapiens (human)	IC50	0.0660	1	1
Breakpoint cluster region protein	Homo sapiens (human)	GI50	20.0000	1	1
Casein kinase I isoform delta	Homo sapiens (human)	IC50	10.0000	1	1
Cyclin-A1	Homo sapiens (human)	IC50	20.0000	1	1
Cyclin-A2	Homo sapiens (human)	IC50	0.5800	1	1
Cyclin-dependent kinase 1	Homo sapiens (human)	IC50	0.7900	1	1
Cyclin-dependent kinase 2	Homo sapiens (human)	IC50	13.5267	3	3
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	IC50	11.8500	2	2
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	IC50	20.0000	1	1
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	IC50	0.8000	1	1
eIF-2-alpha kinase GCN2	Homo sapiens (human)	IC50	0.4500	1	1
Ephrin type-A receptor 2	Homo sapiens (human)	IC50	0.0200	1	1
Ephrin type-B receptor 4	Homo sapiens (human)	IC50	0.1000	1	1
Epidermal growth factor receptor	Homo sapiens (human)	IC50	10.0000	1	1
Fibroblast growth factor receptor 3	Homo sapiens (human)	IC50	0.2800	1	1
G2/mitotic-specific cyclin-B1	Homo sapiens (human)	IC50	0.7900	1	1
Glycogen synthase kinase-3 beta	Homo sapiens (human)	IC50	0.5000	1	1
GTPase KRas	Homo sapiens (human)	IC50	0.1500	1	1
Heat shock factor protein 1	Homo sapiens (human)	IC50	10.0000	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	IC50	10.0000	1	1
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	IC50	3.7000	1	1
Insulin receptor	Homo sapiens (human)	IC50	10.0000	1	1
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	IC50	0.3900	1	1
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	IC50	10.0000	1	1
Mitogen-activated protein kinase 10	Homo sapiens (human)	IC50	0.4700	1	1
Mitogen-activated protein kinase 11	Homo sapiens (human)	IC50	0.0610	1	1
Mitogen-activated protein kinase 12	Homo sapiens (human)	IC50	0.0610	1	1
Mitogen-activated protein kinase 13	Homo sapiens (human)	IC50	0.0610	1	1
Mitogen-activated protein kinase 14	Homo sapiens (human)	IC50	0.3305	2	2
Mitogen-activated protein kinase 3	Homo sapiens (human)	IC50	10.0000	1	1
Mitogen-activated protein kinase 8	Homo sapiens (human)	IC50	5.2350	2	2
Mitogen-activated protein kinase 9	Homo sapiens (human)	IC50	0.4700	1	1
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	IC50	5.0490	2	2
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	IC50	0.0390	1	1
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	IC50	0.9700	1	1
Pirin	Homo sapiens (human)	IC50	10.0000	1	1
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	IC50	0.0420	2	2
Platelet-derived growth factor receptor beta	Homo sapiens (human)	IC50	0.1200	1	1
Platelet-derived growth factor subunit A	Homo sapiens (human)	IC50	0.6100	1	1
Protein kinase C theta type	Homo sapiens (human)	IC50	10.0000	1	1
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	IC50	5.1550	2	2
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	IC50	0.0189	9	9
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Ki	0.0001	2	2
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	IC50	10.0000	1	1
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	GI50	0.2194	12	12
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	IC50	0.1024	45	45
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	IC50	0.0297	3	3
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	IC50	0.2608	24	24
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Ki	0.0001	2	2
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	IC50	1.4000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	GI50	20.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	IC50	0.3800	1	1
Tyrosine-protein kinase CSK	Homo sapiens (human)	IC50	0.2900	1	1
Tyrosine-protein kinase Fyn	Homo sapiens (human)	IC50	0.0910	1	1
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	IC50	10.0000	1	1
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	IC50	2.9840	5	5
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	IC50	4.9000	1	1

Activation Measurements

Protein	Taxonomy	Measurement	Average (mM)	Bioassay(s)	Drugs
26S proteasome regulatory subunit 6B	Homo sapiens (human)	Kd	30.0000	1	1
3-phosphoinositide-dependent protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
5'-AMP-activated protein kinase catalytic subunit alpha-1	Homo sapiens (human)	Kd	16.6667	3	3
5'-AMP-activated protein kinase catalytic subunit alpha-2	Homo sapiens (human)	Kd	10.0000	2	2
5'-AMP-activated protein kinase subunit gamma-1	Homo sapiens (human)	Kd	30.0000	1	1
5'-AMP-activated protein kinase subunit gamma-2	Homo sapiens (human)	Kd	30.0000	1	1
AarF domain-containing protein kinase 1	Homo sapiens (human)	Kd	30.0000	1	1
Actin-related protein 2	Homo sapiens (human)	Kd	30.0000	1	1
Actin-related protein 3	Homo sapiens (human)	Kd	30.0000	1	1
Activated CDC42 kinase 1	Homo sapiens (human)	Kd	20.0000	2	2
Activin receptor type-1	Homo sapiens (human)	Kd	16.6667	3	3
Activin receptor type-1B	Homo sapiens (human)	Kd	16.6667	3	3
Activin receptor type-2A	Homo sapiens (human)	Kd	10.0000	2	2
Activin receptor type-2B	Homo sapiens (human)	Kd	16.6667	3	3
Acyl-CoA dehydrogenase family member 10	Homo sapiens (human)	Kd	30.0000	1	1
Acyl-CoA dehydrogenase family member 11	Homo sapiens (human)	Kd	30.0000	1	1
Adenine phosphoribosyltransferase	Homo sapiens (human)	Kd	30.0000	1	1
Adenosine kinase	Homo sapiens (human)	Kd	30.0000	1	1
Adenylate kinase 2, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
ADP/ATP translocase 2	Homo sapiens (human)	Kd	30.0000	1	1
ADP/ATP translocase 3	Homo sapiens (human)	Kd	30.0000	1	1
ALK tyrosine kinase receptor	Homo sapiens (human)	Kd	10.0000	2	2
Angiopoietin-1 receptor	Homo sapiens (human)	Kd	10.0000	2	2
Ankyrin repeat and protein kinase domain-containing protein 1	Homo sapiens (human)	Kd	10.0000	2	2
AP2-associated protein kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
ATP-dependent 6-phosphofructokinase, platelet type	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX1	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX3X	Homo sapiens (human)	Kd	30.0000	1	1
ATP-dependent RNA helicase DDX42	Homo sapiens (human)	Kd	30.0000	1	1
Atypical kinase COQ8A, mitochondrial	Homo sapiens (human)	Kd	16.6667	3	3
Atypical kinase COQ8B, mitochondrial	Homo sapiens (human)	Kd	10.0000	2	2
Aurora kinase A	Homo sapiens (human)	Kd	16.6667	3	3
Aurora kinase B	Homo sapiens (human)	Kd	16.6667	3	3
Aurora kinase C	Homo sapiens (human)	Kd	10.0000	2	2
BDNF/NT-3 growth factors receptor	Homo sapiens (human)	Kd	0.6200	2	2
Beta-adrenergic receptor kinase 1	Homo sapiens (human)	Kd	30.0000	1	1
BMP-2-inducible protein kinase	Homo sapiens (human)	Kd	16.6667	3	3
Bone morphogenetic protein receptor type-1A	Homo sapiens (human)	Kd	16.6667	3	3
Bone morphogenetic protein receptor type-1B	Homo sapiens (human)	Kd	7.4340	3	3
Bone morphogenetic protein receptor type-2	Homo sapiens (human)	Kd	16.6667	3	3
Breakpoint cluster region protein	Homo sapiens (human)	Kd	30.0000	1	1
Calcium-dependent protein kinase 1	Plasmodium falciparum 3D7	Kd	10.0000	1	1
Calcium/calmodulin-dependent protein kinase kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Calcium/calmodulin-dependent protein kinase type 1	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type 1D	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type 1G	Homo sapiens (human)	Kd	20.0000	2	2
Calcium/calmodulin-dependent protein kinase type II subunit alpha	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type II subunit beta	Homo sapiens (human)	Kd	10.0000	2	2
Calcium/calmodulin-dependent protein kinase type II subunit delta	Homo sapiens (human)	Kd	16.6667	3	3
Calcium/calmodulin-dependent protein kinase type II subunit gamma	Homo sapiens (human)	Kd	15.0000	4	4
Calcium/calmodulin-dependent protein kinase type IV	Homo sapiens (human)	Kd	10.0000	2	2
cAMP-dependent protein kinase catalytic subunit alpha	Homo sapiens (human)	Kd	20.0000	2	2
cAMP-dependent protein kinase catalytic subunit beta	Homo sapiens (human)	Kd	16.6667	3	3
cAMP-dependent protein kinase catalytic subunit gamma	Homo sapiens (human)	Kd	30.0000	1	1
cAMP-dependent protein kinase catalytic subunit PRKX	Homo sapiens (human)	Kd	10.0000	2	2
cAMP-dependent protein kinase type II-alpha regulatory subunit	Homo sapiens (human)	Kd	30.0000	1	1
Casein kinase I isoform alpha	Homo sapiens (human)	Kd	16.6667	3	3
Casein kinase I isoform alpha-like	Homo sapiens (human)	Kd	10.0000	1	1
Casein kinase I isoform delta	Homo sapiens (human)	Kd	16.6667	3	3
Casein kinase I isoform epsilon	Homo sapiens (human)	Kd	16.6667	3	3
Casein kinase I isoform gamma-1	Homo sapiens (human)	Kd	10.0000	2	2
Casein kinase I isoform gamma-2	Homo sapiens (human)	Kd	16.6667	3	3
Casein kinase I isoform gamma-3	Homo sapiens (human)	Kd	16.6667	3	3
Casein kinase II subunit alpha	Homo sapiens (human)	Kd	10.0000	2	2
Casein kinase II subunit alpha'	Homo sapiens (human)	Kd	16.6667	3	3
Cell division control protein 2 homolog	Plasmodium falciparum 3D7	Kd	10.0000	1	1
Cell division cycle 7-related protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
cGMP-dependent protein kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
cGMP-dependent protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Chromodomain-helicase-DNA-binding protein 4	Homo sapiens (human)	Kd	30.0000	1	1
Citron Rho-interacting kinase	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-dependent kinase 1	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 11A	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 11B	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 12	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 13	Homo sapiens (human)	Kd	20.0000	2	2
Cyclin-dependent kinase 14	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 15	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 16	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-dependent kinase 17	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 18	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 19	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-dependent kinase 3	Homo sapiens (human)	Kd	20.0000	3	4
Cyclin-dependent kinase 4	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-dependent kinase 6	Homo sapiens (human)	Kd	30.0000	1	1
Cyclin-dependent kinase 7	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-dependent kinase 8	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase 9	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-dependent kinase-like 1	Homo sapiens (human)	Kd	10.0000	1	1
Cyclin-dependent kinase-like 2	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase-like 3	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent kinase-like 5	Homo sapiens (human)	Kd	10.0000	2	2
Cyclin-dependent-like kinase 5	Homo sapiens (human)	Kd	16.6667	3	3
Cyclin-G-associated kinase	Homo sapiens (human)	Kd	16.6667	3	3
Cysteine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	1
Cytochrome c1, heme protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Cytoplasmic tyrosine-protein kinase BMX	Homo sapiens (human)	Kd	10.0000	2	2
dCTP pyrophosphatase 1	Homo sapiens (human)	Kd	30.0000	1	1
Death-associated protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Death-associated protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Death-associated protein kinase 3	Homo sapiens (human)	Kd	10.0000	2	2
Delta(24)-sterol reductase	Homo sapiens (human)	Kd	30.0000	1	1
Deoxycytidine kinase	Homo sapiens (human)	Kd	30.0000	1	1
Discoidin domain-containing receptor 2	Homo sapiens (human)	Kd	8.1200	4	4
DNA replication licensing factor MCM4	Homo sapiens (human)	Kd	30.0000	1	1
DNA topoisomerase 2-alpha	Homo sapiens (human)	Kd	30.0000	1	1
DNA topoisomerase 2-beta	Homo sapiens (human)	Kd	30.0000	1	1
DnaJ homolog subfamily A member 1	Homo sapiens (human)	Kd	30.0000	1	1
Dual serine/threonine and tyrosine protein kinase	Homo sapiens (human)	Kd	10.0000	1	1
Dual specificity mitogen-activated protein kinase kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity mitogen-activated protein kinase kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity mitogen-activated protein kinase kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity mitogen-activated protein kinase kinase 4	Homo sapiens (human)	Kd	10.0000	2	2
Dual specificity mitogen-activated protein kinase kinase 5	Homo sapiens (human)	Kd	20.0000	2	2
Dual specificity mitogen-activated protein kinase kinase 6	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity mitogen-activated protein kinase kinase 7	Homo sapiens (human)	Kd	10.0000	1	1
Dual specificity protein kinase CLK1	Homo sapiens (human)	Kd	20.0000	3	4
Dual specificity protein kinase CLK2	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity protein kinase CLK3	Homo sapiens (human)	Kd	10.0000	2	2
Dual specificity protein kinase CLK4	Homo sapiens (human)	Kd	10.0000	2	2
Dual specificity protein kinase TTK	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity testis-specific protein kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1A	Homo sapiens (human)	Kd	16.6667	3	3
Dual specificity tyrosine-phosphorylation-regulated kinase 1B	Homo sapiens (human)	Kd	10.0000	2	2
Dual specificity tyrosine-phosphorylation-regulated kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Dynamin-like 120 kDa protein, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
eIF-2-alpha kinase GCN2	Homo sapiens (human)	Kd	10.0000	2	2
EKC/KEOPS complex subunit TP53RK	Homo sapiens (human)	Kd	30.0000	1	1
Electron transfer flavoprotein subunit beta	Homo sapiens (human)	Kd	30.0000	1	1
Elongation factor Tu, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Ephrin type-A receptor 1	Homo sapiens (human)	Kd	20.0000	3	4
Ephrin type-A receptor 2	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-A receptor 3	Homo sapiens (human)	Kd	8.2500	2	2
Ephrin type-A receptor 4	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-A receptor 5	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-A receptor 6	Homo sapiens (human)	Kd	9.5500	2	2
Ephrin type-A receptor 7	Homo sapiens (human)	Kd	6.8500	2	2
Ephrin type-A receptor 8	Homo sapiens (human)	Kd	10.0000	2	2
Ephrin type-B receptor 1	Homo sapiens (human)	Kd	10.0000	2	2
Ephrin type-B receptor 2	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-B receptor 3	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-B receptor 4	Homo sapiens (human)	Kd	16.6667	3	3
Ephrin type-B receptor 6	Homo sapiens (human)	Kd	10.8000	3	3
Epidermal growth factor receptor	Homo sapiens (human)	Kd	11.0526	19	19
Epithelial discoidin domain-containing receptor 1	Homo sapiens (human)	Kd	6.0648	5	5
Eukaryotic peptide chain release factor GTP-binding subunit ERF3B	Homo sapiens (human)	Kd	30.0000	1	1
Eukaryotic translation initiation factor 2-alpha kinase 1	Homo sapiens (human)	Kd	20.0000	2	2
Eukaryotic translation initiation factor 5B	Homo sapiens (human)	Kd	30.0000	1	1
Exosome RNA helicase MTR4	Homo sapiens (human)	Kd	30.0000	1	1
Ferrochelatase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Fibroblast growth factor receptor 1	Homo sapiens (human)	Kd	16.6667	3	3
Fibroblast growth factor receptor 2	Homo sapiens (human)	Kd	10.0000	2	2
Fibroblast growth factor receptor 3	Homo sapiens (human)	Kd	10.0000	4	4
Fibroblast growth factor receptor 4	Homo sapiens (human)	Kd	10.0000	2	2
Focal adhesion kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
G protein-coupled receptor kinase 4	Homo sapiens (human)	Kd	10.0000	2	2
General transcription and DNA repair factor IIH helicase subunit XPD	Homo sapiens (human)	Kd	30.0000	1	1
Glycine--tRNA ligase	Homo sapiens (human)	Kd	30.0000	1	2
Glycogen phosphorylase, brain form	Homo sapiens (human)	Kd	30.0000	1	1
Glycogen phosphorylase, liver form	Homo sapiens (human)	Kd	30.0000	1	1
Glycogen synthase kinase-3 alpha	Homo sapiens (human)	Kd	16.6667	3	3
Glycogen synthase kinase-3 beta	Homo sapiens (human)	Kd	20.0000	3	4
GTP-binding nuclear protein Ran	Homo sapiens (human)	Kd	30.0000	1	1
Guanine nucleotide-binding protein G(i) subunit alpha-2	Homo sapiens (human)	Kd	30.0000	1	1
Heme oxygenase 2	Homo sapiens (human)	Kd	30.0000	1	1
Hepatocyte growth factor receptor	Homo sapiens (human)	Kd	12.8571	7	7
High affinity nerve growth factor receptor	Homo sapiens (human)	Kd	11.5333	3	3
Homeodomain-interacting protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Homeodomain-interacting protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Homeodomain-interacting protein kinase 3	Homo sapiens (human)	Kd	10.0000	2	2
Homeodomain-interacting protein kinase 4	Homo sapiens (human)	Kd	0.3200	2	2
Hormonally up-regulated neu tumor-associated kinase	Homo sapiens (human)	Kd	10.0000	2	2
Inhibitor of nuclear factor kappa-B kinase subunit alpha	Homo sapiens (human)	Kd	10.0000	2	2
Inhibitor of nuclear factor kappa-B kinase subunit beta	Homo sapiens (human)	Kd	10.0000	2	2
Inhibitor of nuclear factor kappa-B kinase subunit epsilon	Homo sapiens (human)	Kd	16.6667	3	3
Inosine-5'-monophosphate dehydrogenase 2	Homo sapiens (human)	Kd	30.0000	1	1
Insulin receptor	Homo sapiens (human)	Kd	16.6667	3	3
Insulin receptor-related protein	Homo sapiens (human)	Kd	10.0000	2	2
Insulin-like growth factor 1 receptor	Homo sapiens (human)	Kd	16.6667	3	3
Integrin-linked protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Interferon-induced, double-stranded RNA-activated protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
Interleukin-1 receptor-associated kinase 1	Homo sapiens (human)	Kd	20.0000	3	4
Interleukin-1 receptor-associated kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
Interleukin-1 receptor-associated kinase 4	Homo sapiens (human)	Kd	20.0000	2	2
Isoleucine--tRNA ligase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Leucine-rich repeat serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
Leukocyte tyrosine kinase receptor	Homo sapiens (human)	Kd	10.0000	2	2
Leukotriene C4 synthase	Cavia porcellus (domestic guinea pig)	Kd	10.0000	1	1
LIM domain kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
LIM domain kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Macrophage colony-stimulating factor 1 receptor	Homo sapiens (human)	Kd	0.0104	6	6
Macrophage-stimulating protein receptor	Homo sapiens (human)	Kd	16.6667	3	3
MAP kinase-activated protein kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
MAP kinase-activated protein kinase 5	Homo sapiens (human)	Kd	16.6667	3	3
MAP kinase-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
MAP kinase-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	2.6000	2	2
MAP/microtubule affinity-regulating kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
MAP/microtubule affinity-regulating kinase 4	Homo sapiens (human)	Kd	16.6667	3	3
Mast/stem cell growth factor receptor Kit	Homo sapiens (human)	Kd	0.0420	18	18
Maternal embryonic leucine zipper kinase	Homo sapiens (human)	Kd	16.6667	3	3
Megakaryocyte-associated tyrosine-protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
Membrane-associated progesterone receptor component 1	Homo sapiens (human)	Kd	30.0000	1	1
Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase	Homo sapiens (human)	Kd	16.6667	3	3
Microtubule-associated serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
Midasin	Homo sapiens (human)	Kd	30.0000	1	1
Misshapen-like kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 10	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 11	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 12	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 13	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 14	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 15	Homo sapiens (human)	Kd	10.1800	3	3
Mitogen-activated protein kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 4	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 6	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase 7	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 8	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase 9	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 10	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase kinase kinase 11	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 12	Homo sapiens (human)	Kd	10.0000	1	1
Mitogen-activated protein kinase kinase kinase 13	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase kinase kinase 15	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase kinase kinase 19	Homo sapiens (human)	Kd	2.0000	2	2
Mitogen-activated protein kinase kinase kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 20	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 4	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 5	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 6	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase 7	Homo sapiens (human)	Kd	8.5000	2	2
Mitogen-activated protein kinase kinase kinase 9	Homo sapiens (human)	Kd	10.0000	2	2
Mitogen-activated protein kinase kinase kinase kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
Mitogen-activated protein kinase kinase kinase kinase 4	Homo sapiens (human)	Kd	11.6667	3	3
Mitogen-activated protein kinase kinase kinase kinase 5	Homo sapiens (human)	Kd	10.2933	3	3
Mitotic checkpoint serine/threonine-protein kinase BUB1	Homo sapiens (human)	Kd	30.0000	1	1
Multifunctional protein ADE2	Homo sapiens (human)	Kd	30.0000	1	1
Muscle, skeletal receptor tyrosine-protein kinase	Homo sapiens (human)	Kd	1.0000	2	2
Myosin light chain kinase 2, skeletal/cardiac muscle	Homo sapiens (human)	Kd	10.0000	2	2
Myosin light chain kinase 3	Homo sapiens (human)	Kd	15.2050	2	2
Myosin light chain kinase family member 4	Homo sapiens (human)	Kd	10.0000	2	2
Myosin light chain kinase, smooth muscle	Homo sapiens (human)	Kd	12.6025	4	4
Myosin-10	Homo sapiens (human)	Kd	0.7580	1	1
Myosin-14	Homo sapiens (human)	Kd	30.0000	1	1
Myosin-IIIa	Homo sapiens (human)	Kd	10.0000	2	2
Myosin-IIIb	Homo sapiens (human)	Kd	10.0000	2	2
Myotonin-protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 13	Homo sapiens (human)	Kd	30.0000	1	1
Non-receptor tyrosine-protein kinase TNK1	Homo sapiens (human)	Kd	16.6667	3	3
Non-receptor tyrosine-protein kinase TYK2	Homo sapiens (human)	Kd	14.0000	5	5
NT-3 growth factor receptor	Homo sapiens (human)	Kd	0.5500	2	2
NUAK family SNF1-like kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
NUAK family SNF1-like kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Nucleolar GTP-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	1
Obg-like ATPase 1	Homo sapiens (human)	Kd	30.0000	1	1
PAS domain-containing serine/threonine-protein kinase	Homo sapiens (human)	Kd	30.0000	1	1
Peripheral plasma membrane protein CASK	Homo sapiens (human)	Kd	10.0000	1	1
Peroxisomal acyl-coenzyme A oxidase 3	Homo sapiens (human)	Kd	30.0000	1	1
Phenylalanine--tRNA ligase beta subunit	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylethanolamine-binding protein 1	Homo sapiens (human)	Kd	30.0000	1	1
Phosphatidylinositol 4-kinase beta	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit gamma	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma	Homo sapiens (human)	Kd	10.0000	1	1
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	Homo sapiens (human)	Kd	10.0000	19	19
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 beta	Homo sapiens (human)	Kd	10.0000	2	2
Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma	Homo sapiens (human)	Kd	20.0000	2	2
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform	Homo sapiens (human)	Kd	16.6667	3	3
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform	Homo sapiens (human)	Kd	10.0000	2	2
Platelet-derived growth factor receptor alpha	Homo sapiens (human)	Kd	0.0089	6	6
Platelet-derived growth factor receptor beta	Homo sapiens (human)	Kd	4.2909	7	7
Poly [ADP-ribose] polymerase tankyrase-2	Homo sapiens (human)	Kd	10.0000	1	1
Probable ATP-dependent RNA helicase DDX6	Homo sapiens (human)	Kd	30.0000	1	1
Prostaglandin G/H synthase 2	Homo sapiens (human)	Kd	10.0000	1	1
Protein delta homolog 1	Homo sapiens (human)	Kd	10.0000	1	1
Protein kinase C alpha type	Homo sapiens (human)	Kd	20.0000	2	2
Protein kinase C beta type	Homo sapiens (human)	Kd	30.0000	1	1
Protein kinase C delta type	Homo sapiens (human)	Kd	20.0000	3	4
Protein kinase C epsilon type	Homo sapiens (human)	Kd	10.0000	2	2
Protein kinase C eta type	Homo sapiens (human)	Kd	10.0000	2	2
Protein kinase C iota type	Homo sapiens (human)	Kd	20.0000	2	2
Protein kinase C theta type	Homo sapiens (human)	Kd	16.6667	3	3
Protein-tyrosine kinase 2-beta	Homo sapiens (human)	Kd	16.6667	3	3
Protein-tyrosine kinase 6	Homo sapiens (human)	Kd	20.0000	3	4
Proto-oncogene tyrosine-protein kinase receptor Ret	Homo sapiens (human)	Kd	0.0204	13	13
Proto-oncogene tyrosine-protein kinase ROS	Homo sapiens (human)	Kd	10.0000	2	2
Proto-oncogene tyrosine-protein kinase Src	Homo sapiens (human)	Kd	16.6667	3	3
Putative heat shock protein HSP 90-beta 2	Homo sapiens (human)	Kd	30.0000	1	1
Pyridoxal kinase	Homo sapiens (human)	Kd	30.0000	1	1
RAC-alpha serine/threonine-protein kinase	Homo sapiens (human)	Kd	16.6667	3	3
RAC-beta serine/threonine-protein kinase	Homo sapiens (human)	Kd	16.6667	3	3
RAC-gamma serine/threonine-protein kinase	Homo sapiens (human)	Kd	16.6667	3	3
RAF proto-oncogene serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
Ras-related protein Rab-10	Homo sapiens (human)	Kd	30.0000	1	1
Ras-related protein Rab-27A	Homo sapiens (human)	Kd	30.0000	1	1
Ras-related protein Rab-6A	Homo sapiens (human)	Kd	30.0000	1	1
Receptor tyrosine-protein kinase erbB-2	Homo sapiens (human)	Kd	10.0000	2	2
Receptor tyrosine-protein kinase erbB-3	Homo sapiens (human)	Kd	10.0000	2	2
Receptor tyrosine-protein kinase erbB-4	Homo sapiens (human)	Kd	10.0000	2	2
Receptor-interacting serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	2.5480	5	5
Receptor-interacting serine/threonine-protein kinase 2	Homo sapiens (human)	Kd	14.2333	3	3
Receptor-interacting serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	10.0700	3	3
Receptor-interacting serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	10.0000	2	2
Receptor-type tyrosine-protein kinase FLT3	Homo sapiens (human)	Kd	0.0362	28	28
Rho-associated protein kinase 1	Homo sapiens (human)	Kd	16.6667	3	3
Rho-associated protein kinase 2	Homo sapiens (human)	Kd	16.6667	3	3
Rhodopsin kinase GRK1	Homo sapiens (human)	Kd	10.0000	2	2
Rhodopsin kinase GRK7	Homo sapiens (human)	Kd	10.0000	2	2
Ribosomal protein S6 kinase alpha-1	Homo sapiens (human)	Kd	14.0000	5	5
Ribosomal protein S6 kinase alpha-2	Homo sapiens (human)	Kd	10.0000	4	4
Ribosomal protein S6 kinase alpha-3	Homo sapiens (human)	Kd	20.0000	3	4
Ribosomal protein S6 kinase alpha-4	Homo sapiens (human)	Kd	14.0000	5	5
Ribosomal protein S6 kinase alpha-5	Homo sapiens (human)	Kd	14.0000	5	5
Ribosomal protein S6 kinase alpha-6	Homo sapiens (human)	Kd	14.0000	5	5
Ribosomal protein S6 kinase beta-1	Homo sapiens (human)	Kd	16.6667	3	3
Ribosyldihydronicotinamide dehydrogenase [quinone]	Homo sapiens (human)	Kd	30.0000	1	1
RNA cytidine acetyltransferase	Homo sapiens (human)	Kd	30.0000	1	1
S-adenosylmethionine synthase isoform type-2	Homo sapiens (human)	Kd	30.0000	1	2
Septin-9	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase 10	Homo sapiens (human)	Kd	13.8333	3	3
Serine/threonine-protein kinase 16	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase 17A	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 17B	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 24	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 25	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 26	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase 3	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase 32A	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase 32B	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 32C	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 33	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 35	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 36	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 38	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 38-like	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase 4	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase A-Raf	Homo sapiens (human)	Kd	30.0000	1	1
Serine/threonine-protein kinase B-raf	Homo sapiens (human)	Kd	14.0000	5	5
Serine/threonine-protein kinase BRSK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase BRSK2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Chk1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase Chk2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase D1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase D2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase D3	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase DCLK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase DCLK2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase DCLK3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase ICK	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase LATS1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase LATS2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase MAK	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase MARK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase MARK2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase MRCK alpha	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase MRCK beta	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase MRCK gamma	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase mTOR	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase N1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase N2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase Nek1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase Nek11	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase Nek2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase Nek3	Homo sapiens (human)	Kd	20.0000	2	2
Serine/threonine-protein kinase Nek4	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase Nek5	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Nek6	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase Nek7	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase Nek9	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase NIM1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase NLK	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase OSR1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 2	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase PAK 3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 4	Homo sapiens (human)	Kd	20.0000	3	4
Serine/threonine-protein kinase PAK 5	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PAK 6	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase pim-1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase pim-2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase pim-3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PknB	Mycobacterium tuberculosis H37Rv	Kd	10.0000	1	1
Serine/threonine-protein kinase PLK1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase PLK2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PLK3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase PLK4	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase PRP4 homolog	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase receptor R3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase RIO1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase RIO2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase RIO3	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase SBK1	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase Sgk3	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase SIK1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase SIK2	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase SIK3	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase STK11	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase TAO1	Homo sapiens (human)	Kd	15.0000	4	4
Serine/threonine-protein kinase TAO2	Homo sapiens (human)	Kd	20.0000	2	2
Serine/threonine-protein kinase TAO3	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase TBK1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase TNNI3K	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase tousled-like 1	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase tousled-like 2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase ULK1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase ULK2	Homo sapiens (human)	Kd	10.0000	2	2
Serine/threonine-protein kinase ULK3	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase VRK2	Homo sapiens (human)	Kd	10.0000	1	1
Serine/threonine-protein kinase/endoribonuclease IRE1	Homo sapiens (human)	Kd	16.6667	3	3
Serine/threonine-protein kinase/endoribonuclease IRE2	Homo sapiens (human)	Kd	30.0000	1	1
SNF-related serine/threonine-protein kinase	Homo sapiens (human)	Kd	10.0000	1	1
SRSF protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
SRSF protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2
SRSF protein kinase 3	Homo sapiens (human)	Kd	10.0000	2	2
STE20-like serine/threonine-protein kinase	Homo sapiens (human)	Kd	14.8667	3	3
STE20-related kinase adapter protein alpha	Homo sapiens (human)	Kd	30.0000	1	1
STE20/SPS1-related proline-alanine-rich protein kinase	Homo sapiens (human)	Kd	10.0000	2	2
Structural maintenance of chromosomes protein 1A	Homo sapiens (human)	Kd	30.0000	1	1
Structural maintenance of chromosomes protein 2	Homo sapiens (human)	Kd	30.0000	1	1
Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Testis-specific serine/threonine-protein kinase 1	Homo sapiens (human)	Kd	10.0000	2	2
TGF-beta receptor type-1	Homo sapiens (human)	Kd	16.6667	3	3
TGF-beta receptor type-2	Homo sapiens (human)	Kd	16.6667	3	3
TRAF2 and NCK-interacting protein kinase	Homo sapiens (human)	Kd	6.4000	2	2
Transient receptor potential cation channel subfamily M member 6	Homo sapiens (human)	Kd	10.0000	1	1
Tyrosine--tRNA ligase, cytoplasmic	Homo sapiens (human)	Kd	30.0000	1	1
Tyrosine-protein kinase ABL1	Homo sapiens (human)	Kd	10.1168	25	25
Tyrosine-protein kinase ABL2	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase Blk	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase BTK	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase CSK	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase Fer	Homo sapiens (human)	Kd	20.0000	3	4
Tyrosine-protein kinase Fes/Fps	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase Fgr	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase FRK	Homo sapiens (human)	Kd	11.2000	3	3
Tyrosine-protein kinase Fyn	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase HCK	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase ITK/TSK	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase JAK1	Homo sapiens (human)	Kd	14.0000	5	5
Tyrosine-protein kinase JAK2	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase JAK3	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase Lck	Homo sapiens (human)	Kd	14.1667	3	3
Tyrosine-protein kinase Lyn	Homo sapiens (human)	Kd	15.2333	3	3
Tyrosine-protein kinase Mer	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase receptor Tie-1	Homo sapiens (human)	Kd	3.2000	2	2
Tyrosine-protein kinase receptor TYRO3	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase receptor UFO	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase Srms	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase SYK	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase Tec	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase TXK	Homo sapiens (human)	Kd	10.0000	2	2
Tyrosine-protein kinase Yes	Homo sapiens (human)	Kd	16.6667	3	3
Tyrosine-protein kinase ZAP-70	Homo sapiens (human)	Kd	10.0000	2	2
U5 small nuclear ribonucleoprotein 200 kDa helicase	Homo sapiens (human)	Kd	30.0000	1	1
UMP-CMP kinase	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized aarF domain-containing protein kinase 5	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized protein FLJ45252	Homo sapiens (human)	Kd	30.0000	1	1
Uncharacterized serine/threonine-protein kinase SBK3	Homo sapiens (human)	Kd	10.0000	2	2
Vascular endothelial growth factor receptor 1	Homo sapiens (human)	Kd	0.0410	4	4
Vascular endothelial growth factor receptor 2	Homo sapiens (human)	Kd	0.0870	3	3
Vascular endothelial growth factor receptor 3	Homo sapiens (human)	Kd	0.0410	4	4
Very long-chain specific acyl-CoA dehydrogenase, mitochondrial	Homo sapiens (human)	Kd	30.0000	1	1
Wee1-like protein kinase	Homo sapiens (human)	Kd	16.6667	3	3
Wee1-like protein kinase 2	Homo sapiens (human)	Kd	10.0000	2	2