probenecid has been researched along with Osteomyelitis in 9 studies
Probenecid: The prototypical uricosuric agent. It inhibits the renal excretion of organic anions and reduces tubular reabsorption of urate. Probenecid has also been used to treat patients with renal impairment, and, because it reduces the renal tubular excretion of other drugs, has been used as an adjunct to antibacterial therapy.
probenecid : A sulfonamide in which the nitrogen of 4-sulfamoylbenzoic acid is substituted with two propyl groups.
Osteomyelitis: INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections." | 7.66 | Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980) |
| "The therapeutic efficacy of decloxacillin or flucloxacillin, 1--2 g orally with probenecid twice daily was evaluated in staphylococcal infections." | 3.66 | Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation. ( Hedström, SA; Kahlmeter, G, 1980) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KOENIG, MG | 1 |
| Hedström, SA | 2 |
| Kahlmeter, G | 1 |
| Brogden, RN | 1 |
| Heel, RC | 1 |
| Speight, TM | 1 |
| Avery, GS | 1 |
| Prober, CG | 1 |
| Yeager, AS | 1 |
| Ceilley, RI | 1 |
| Bell, SM | 1 |
| Limongelli, WA | 1 |
| Connaughton, B | 1 |
| Williams, AC | 1 |
| Knudsen, ET | 1 |
2 reviews available for probenecid and Osteomyelitis
| Article | Year |
|---|---|
THE TREATMENT OF STAPHYLOCOCCAL INFECTIONS.
Topics: Animals; Anti-Bacterial Agents; Antitoxins; Bacitracin; Carrier State; Erythromycin; Furunculosis; H | 1963 |
Cefuroxime: a review of its antibacterial activity, pharmacological properties and therapeutic use.
Topics: Adult; Bacteria; Cephalosporins; Child; Drug Resistance, Microbial; Female; Furans; Gonorrhea; Human | 1979 |
7 other studies available for probenecid and Osteomyelitis
| Article | Year |
|---|---|
Dicloxacillin and flucloxacillin twice daily with probenecid in staphylococcal infections. A clinical and pharmakokinetic evaluation.
Topics: Cloxacillin; Dicloxacillin; Drug Combinations; Drug Evaluation; Drug Therapy, Combination; Floxacill | 1980 |
Use of the serum bactericidal titer to assess the adequacy of oral antibiotic therapy in the treatment of acute hematogenous osteomyelitis.
Topics: Administration, Oral; Adolescent; Anti-Bacterial Agents; Cephalexin; Child; Child, Preschool; Diclox | 1979 |
Foot ulceration and vertebral osteomyelitis with Corynebacterium haemolyticum.
Topics: Aged; Ampicillin; Corynebacterium Infections; Diabetes Complications; Female; Humans; Leg Ulcer; Ost | 1977 |
Oral penicillins in the treatment of chronic staphylococcal osteomyelitis.
Topics: Adolescent; Adult; Child; Cloxacillin; Female; Humans; Male; Middle Aged; Osteomyelitis; Penicillin | 1968 |
Suppurative osteomyelitis of the mandible secondary to fracture. Report of a case.
Topics: Adult; Bacitracin; Carbenicillin; Cephalothin; Escherichia coli; Female; Fracture Fixation; Fracture | 1974 |
[Factors, affecting penicillin therapy].
Topics: Ampicillin; Anti-Bacterial Agents; Antineoplastic Agents; Bronchitis; Carbenicillin; Cloxacillin; Do | 1971 |
General and local antibiotic treatment of chronic osteomyelitis.
Topics: Administration, Oral; Adolescent; Adult; Aged; Blood Sedimentation; C-Reactive Protein; Child; Chlor | 1969 |