Page last updated: 2024-10-23

aztreonam and Osteomyelitis

aztreonam has been researched along with Osteomyelitis in 11 studies

Aztreonam: A monocyclic beta-lactam antibiotic originally isolated from Chromobacterium violaceum. It is resistant to beta-lactamases and is used in gram-negative infections, especially of the meninges, bladder, and kidneys. It may cause a superinfection with gram-positive organisms.
aztreonam : A synthetic monocyclic beta-lactam antibiotic (monobactam), used primarily to treat infections caused by Gram-negative bacteria. It inhibits mucopeptide synthesis in the bacterial cell wall, thereby blocking peptidoglycan crosslinking.

Osteomyelitis: INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.

Research Excerpts

ExcerptRelevanceReference
"Aztreonam seems to be an effective single agent therapy for many bacterial infections."5.27Evaluation of aztreonam in the treatment of severe bacterial infections. ( Bouza, E; García de la Torre, M; Guerrero, A; Hellín, T; Martínez-Beltrán, J; Rodríguez-Créixems, M; Romero-Vivas, J, 1985)
" Dosage of aztreonam was 2 to 8 g per day administered intravenously or intramuscularly for five to 52 days."2.66Aztreonam in the treatment of serious orthopedic infections. ( Beskin, J; Beville, R; Haddad, RJ; Holmes, B; Mogabgab, WJ; Pollock, B; Pribyl, C; Salzer, R, 1985)
"Aztreonam was used for a year to treat 106 hospitalized patients with a total of 131 documented gram-negative infections."1.27Treatment of serious gram-negative infections with aztreonam. ( Bollinger, M; Darji, TB; Greenberg, RN; Luppen, KL; McMillian, R; Noorani, AA; Reilly, PM; Wolk, SM, 1984)
"Aztreonam seems to be an effective single agent therapy for many bacterial infections."1.27Evaluation of aztreonam in the treatment of severe bacterial infections. ( Bouza, E; García de la Torre, M; Guerrero, A; Hellín, T; Martínez-Beltrán, J; Rodríguez-Créixems, M; Romero-Vivas, J, 1985)
"Aztreonam is a novel antimicrobial agent belonging to the monobactam class of antibiotics."1.27Use of aztreonam in the treatment of serious infections due to multiresistant gram-negative organisms, including Pseudomonas aeruginosa. ( Neu, HC; Scully, BE, 1985)

Research

Studies (11)

TimeframeStudies, this research(%)All Research%
pre-19907 (63.64)18.7374
1990's0 (0.00)18.2507
2000's1 (9.09)29.6817
2010's1 (9.09)24.3611
2020's2 (18.18)2.80

Authors

AuthorsStudies
Wei, J1
Zhou, S1
Gu, H1
Tong, K1
Mularoni, A1
Mezzatesta, ML1
Pilato, M1
Medaglia, AA1
Cervo, A1
Bongiorno, D1
Aprile, A1
Luca, A1
Stefani, S1
Grossi, P1
Mittal, J1
Szymczak, WA1
Guo, Y1
Levi, MH1
Chen, L1
Kreiswirth, BN1
Riska, PF1
Nori, P1
Djalilian, HR1
Shamloo, B1
Thakkar, KH1
Najme-Rahim, M1
Greenberg, RN2
Reilly, PM1
Luppen, KL1
McMillian, R1
Bollinger, M1
Wolk, SM1
Darji, TB1
Noorani, AA1
Norden, CW1
Budinsky, A1
Smith, DW1
Wilson, RD1
Perry, CR1
Ellington, LL1
Becker, A1
Vossen, MK1
Burdge, RE1
Romero-Vivas, J1
Rodríguez-Créixems, M1
Bouza, E1
Hellín, T1
Guerrero, A1
Martínez-Beltrán, J1
García de la Torre, M1
Pribyl, C1
Salzer, R1
Beskin, J1
Haddad, RJ1
Pollock, B1
Beville, R1
Holmes, B1
Mogabgab, WJ1
Scully, BE1
Neu, HC1

Trials

1 trial available for aztreonam and Osteomyelitis

ArticleYear
Aztreonam in the treatment of serious orthopedic infections.
    The American journal of medicine, 1985, Feb-08, Volume: 78, Issue:2A

    Topics: Adult; Aged; Anti-Bacterial Agents; Arthritis, Infectious; Aztreonam; Bacterial Infections; Clinical

1985

Other Studies

10 other studies available for aztreonam and Osteomyelitis

ArticleYear
Meropenem-loaded Cement Is Effective in Preventing Gram-negative Osteomyelitis in an Animal Model.
    Clinical orthopaedics and related research, 2023, 01-01, Volume: 481, Issue:1

    Topics: Animals; Anti-Bacterial Agents; Aztreonam; Bone Cements; Ceftazidime; Ciprofloxacin; Escherichia col

2023
Combination of aztreonam, ceftazidime-avibactam and amikacin in the treatment of VIM-1 Pseudomonas aeruginosa ST235 osteomyelitis.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2021, Volume: 108

    Topics: Aged; Amikacin; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; Ceftazidime; Debridement; Dr

2021
Two for the price of one: emerging carbapenemases in a returning traveller to New York City.
    BMJ case reports, 2018, Jul-18, Volume: 2018

    Topics: Adult; Anti-Bacterial Agents; Azabicyclo Compounds; Aztreonam; beta-Lactamase Inhibitors; Ceftazidim

2018
Treatment of culture-negative skull base osteomyelitis.
    Otology & neurotology : official publication of the American Otological Society, American Neurotology Society [and] European Academy of Otology and Neurotology, 2006, Volume: 27, Issue:2

    Topics: Administration, Topical; Adult; Aged; Aged, 80 and over; Anti-Infective Agents; Aztreonam; Ceftazidi

2006
Treatment of serious gram-negative infections with aztreonam.
    The Journal of infectious diseases, 1984, Volume: 150, Issue:5

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Aztreonam; Bacterial Infections; Drug Evaluation; En

1984
Aztreonam therapy for experimental osteomyelitis caused by Pseudomonas aeruginosa.
    The Journal of infectious diseases, 1988, Volume: 158, Issue:3

    Topics: Animals; Aztreonam; Osteomyelitis; Pseudomonas Infections; Rabbits

1988
Treatment of Pseudomonas aeruginosa osteomyelitis with aztreonam.
    The Medical journal of Australia, 1987, Aug-03, Volume: 147, Issue:3

    Topics: Adult; Aztreonam; Female; Humans; Osteomyelitis; Pseudomonas Infections

1987
Antibiotic stability in an implantable pump.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1986, Volume: 4, Issue:4

    Topics: Amikacin; Anti-Bacterial Agents; Aztreonam; Clindamycin; Drug Stability; Gentamicins; Humans; Infusi

1986
Evaluation of aztreonam in the treatment of severe bacterial infections.
    Antimicrobial agents and chemotherapy, 1985, Volume: 28, Issue:2

    Topics: Adolescent; Adult; Aged; Aztreonam; Bacterial Infections; Child; Humans; Middle Aged; Osteomyelitis;

1985
Use of aztreonam in the treatment of serious infections due to multiresistant gram-negative organisms, including Pseudomonas aeruginosa.
    The American journal of medicine, 1985, Volume: 78, Issue:2

    Topics: Adolescent; Adult; Aged; Anti-Bacterial Agents; Arthritis, Infectious; Aztreonam; Bacterial Infectio

1985