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oxyquinoline and Osteomyelitis

oxyquinoline has been researched along with Osteomyelitis in 31 studies

Oxyquinoline: An antiseptic with mild fungistatic, bacteriostatic, anthelmintic, and amebicidal action. It is also used as a reagent and metal chelator, as a carrier for radio-indium for diagnostic purposes, and its halogenated derivatives are used in addition as topical anti-infective agents and oral antiamebics.
quinolin-8-ol : A monohydroxyquinoline that is quinoline substituted by a hydroxy group at position 8. Its fungicidal properties are used for the control of grey mould on vines and tomatoes.

Osteomyelitis: INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.

Research Excerpts

ExcerptRelevanceReference
"Osteomyelitis is a common clinical problem that may be difficult to diagnose."5.27Indium-111 chloride scintigraphy in adult osteomyelitis. ( Ehrlich, LE; Iles, SE; Martin, RH; Saliken, JC, 1987)
" Indium-111 leukocytes are the agent of choice for evaluation of patients with fever of unknown origin, osteomyelitis, and prosthetic graft infections; and preliminary data shows great promise in the area of detecting reoccurrence of inflammatory bowel disease."4.76Imaging of inflammatory processes with labeled cells. ( Froelich, JW; Swanson, D, 1984)
"As an established infection-imaging modality, nuclear medicine plays a vital health-care role in the diagnosis and subsequent effective treatment of this condition."2.42Nuclear medicine and infection detection: the relative effectiveness of imaging with 111In-oxine-, 99mTc-HMPAO-, and 99mTc-stannous fluoride colloid-labeled leukocytes and with 67Ga-citrate. ( Hughes, DK, 2003)
"Osteomyelitis was confirmed by histopathology in all the successfully infected rabbits used for imaging."1.46Scintigraphic Patterns of Indium-111 Oxine-Labeled White Blood Cell Imaging of Gram-Negative versus Gram-Positive Vertebral Osteomyelitis. ( Dannoon, S; Elgazzar, AH; Farghali, M; Junaid, TA; Sarikaya, I, 2017)
"In these sites, uptake correlates with infection or the true cause of the patients' fever in only 10% to 50% of cases."1.29Indium-111-labeled leukocytes for the detection of infection: current status. ( Datz, FL, 1994)
"Osteomyelitis was confirmed in nine of the pathologic specimens."1.29Role of magnetic resonance imaging in the diagnosis of osteomyelitis in diabetic foot infections. ( Croll, SD; Jones, S; Nicholas, GG; Osborne, MA; Wasser, TE, 1996)
"Osteomyelitis is a common clinical problem that may be difficult to diagnose."1.27Indium-111 chloride scintigraphy in adult osteomyelitis. ( Ehrlich, LE; Iles, SE; Martin, RH; Saliken, JC, 1987)
" The use of 99Tcm is scintigraphically more advantageous and, with the dosage required, the absorbed radiation dose to the red bone marrow is three times lower than with 111In granulocytes."1.2799Tcm-labelled HSA-nanocolloid versus 111In oxine-labelled granulocytes in detecting skeletal septic process. ( de Schrijver, M; Fridrich, R; Streule, K, 1988)
"Twenty-five of 29 foci of bacterial infection were demonstrated on the leukocyte-labeled images (sensitivity of detection = 86%)."1.27In-111 labeled leukocytes: a review of problems in image interpretation. ( McAfee, JG; Samin, A, 1985)
"Acute osteomyelitis was induced in 18 rabbits after direct injection of a solution of Staphylococcus aureus culture into a proximal tibial metaphysis."1.26Acute osteomyelitis: advantage of white cell scans in early detection. ( Doherty, PW; Gantz, NM; Goss, TP; Johnson, K; King, MA; Raptopoulos, V, 1982)

Research

Studies (31)

TimeframeStudies, this research(%)All Research%
pre-199018 (58.06)18.7374
1990's10 (32.26)18.2507
2000's2 (6.45)29.6817
2010's1 (3.23)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Elgazzar, AH1
Dannoon, S1
Sarikaya, I1
Farghali, M1
Junaid, TA1
Dinh, MT1
Abad, CL1
Safdar, N1
Hughes, DK1
Raptopoulos, V1
Doherty, PW1
Goss, TP1
King, MA1
Johnson, K1
Gantz, NM1
Froelich, JW1
Swanson, D1
Schauwecker, DS1
Datz, FL2
Croll, SD1
Nicholas, GG1
Osborne, MA1
Wasser, TE1
Jones, S1
Ghesani, M1
Depuey, EG1
Parmett, S1
Derogatis, A1
Melancon, S1
Riskina, R1
Newman, LG2
Waller, J2
Palestro, CJ2
Hermann, G2
Klein, MJ2
Schwartz, M2
Harrington, E2
Harrington, M2
Roman, SH2
Stagnaro-Green, A2
Eisenberg, B1
Powe, JE1
Alavi, A2
Kostadinova, I1
Doĭchinov, A1
Kŭnev, V1
Kovacheva, S1
Buscombe, JR1
Lui, D1
Ensing, G1
de Jong, R1
Ell, PJ1
Becker, W1
Marienhagen, J1
Ordnung, D1
Wolf, F1
Taborski, U1
Bartenstein, P1
Müller, N1
Böttger, J1
Naegele-Woehrle, B1
Kessel, KF1
Weilemann, LS1
Lotz, R1
Hahn, K1
Esterhai, JL1
Goll, SR1
McCarthy, KE1
Velchik, M1
Brighton, CT1
Heppenstall, RB1
Thorne, DA1
Kim, EE1
Pjura, GA1
Lowry, PA1
Gobuty, AH1
Traina, JF1
Götzfried, HF1
Paulus, GW1
Feistel, H1
Neukam, FW1
Laue, A1
Schwarzrock, R1
Iles, SE1
Ehrlich, LE1
Saliken, JC1
Martin, RH1
Wukich, DK1
Abreu, SH1
Callaghan, JJ1
Van Nostrand, D1
Savory, CG1
Eggli, DF1
Garcia, JE1
Berrey, BH1
Strobl-Jäger, E1
Kolbe, H1
Ludwig, H1
Sinzinger, H2
Simon, WH1
Joseph, WS1
Streule, K1
de Schrijver, M1
Fridrich, R1
Granegger, S1
Eichler, HG1
Gasic, S1
Korn, A1
Merkel, KD1
Brown, ML1
Dewanjee, MK1
Fitzgerald, RH1
McAfee, JG1
Samin, A1

Reviews

4 reviews available for oxyquinoline and Osteomyelitis

ArticleYear
Diagnostic accuracy of the physical examination and imaging tests for osteomyelitis underlying diabetic foot ulcers: meta-analysis.
    Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008, Aug-15, Volume: 47, Issue:4

    Topics: Diabetic Foot; Diagnostic Imaging; Humans; Indium Radioisotopes; Leukocytes; Magnetic Resonance Imag

2008
Nuclear medicine and infection detection: the relative effectiveness of imaging with 111In-oxine-, 99mTc-HMPAO-, and 99mTc-stannous fluoride colloid-labeled leukocytes and with 67Ga-citrate.
    Journal of nuclear medicine technology, 2003, Volume: 31, Issue:4

    Topics: Citrates; Fever of Unknown Origin; Gallium; Humans; Infections; Irritable Bowel Syndrome; Leukocytes

2003
Imaging of inflammatory processes with labeled cells.
    Seminars in nuclear medicine, 1984, Volume: 14, Issue:2

    Topics: Abscess; Blood Vessel Prosthesis; Colitis, Ulcerative; Crohn Disease; Cytomegalovirus Infections; En

1984
Clinical imaging with indium 111 oxine-labeled leukocyte scan: review and case report.
    Clinics in podiatric medicine and surgery, 1988, Volume: 5, Issue:2

    Topics: Adult; Diabetes Mellitus, Type 1; Diagnosis, Differential; Foot Diseases; Gallium Radioisotopes; Hum

1988

Other Studies

27 other studies available for oxyquinoline and Osteomyelitis

ArticleYear
Scintigraphic Patterns of Indium-111 Oxine-Labeled White Blood Cell Imaging of Gram-Negative versus Gram-Positive Vertebral Osteomyelitis.
    Medical principles and practice : international journal of the Kuwait University, Health Science Centre, 2017, Volume: 26, Issue:5

    Topics: Animals; Disease Models, Animal; Escherichia coli; Escherichia coli Infections; Femur; Leukocytes; L

2017
Acute osteomyelitis: advantage of white cell scans in early detection.
    AJR. American journal of roentgenology, 1982, Volume: 139, Issue:6

    Topics: Animals; Diphosphonates; Hindlimb; Hydroxyquinolines; Indium; Leukocytes; Organometallic Compounds;

1982
Differentiation of infected from noninfected rapidly progressive neuropathic osteoarthropathy.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:8

    Topics: Adult; Aged; Arthropathy, Neurogenic; Diabetes Complications; Diagnosis, Differential; Female; Human

1995
Indium-111-labeled leukocytes for the detection of infection: current status.
    Seminars in nuclear medicine, 1994, Volume: 24, Issue:2

    Topics: Chronic Disease; Digestive System; Humans; Indium Radioisotopes; Infections; Leukocytes; Lung; Organ

1994
Role of magnetic resonance imaging in the diagnosis of osteomyelitis in diabetic foot infections.
    Journal of vascular surgery, 1996, Volume: 24, Issue:2

    Topics: Adult; Aged; Aged, 80 and over; Costs and Cost Analysis; Diabetic Foot; Female; Humans; Indium Radio

1996
Importance of dressing removal before radiolabeled WBC imaging for musculoskeletal infection.
    Clinical nuclear medicine, 1996, Volume: 21, Issue:7

    Topics: Adult; Bandages; Bone and Bones; False Positive Reactions; Humans; Indium Radioisotopes; Leukocytes;

1996
Leukocyte scanning with 111In is superior to magnetic resonance imaging in diagnosis of clinically unsuspected osteomyelitis in diabetic foot ulcers.
    Diabetes care, 1992, Volume: 15, Issue:11

    Topics: Biopsy; Bone and Bones; Diabetes Complications; Foot Ulcer; Humans; Indium Radioisotopes; Leukocytes

1992
Cold defects in in-111 labeled leukocyte imaging of osteomyelitis in the axial skeleton.
    Clinical nuclear medicine, 1991, Volume: 16, Issue:2

    Topics: Humans; Indium Radioisotopes; Leukocytes; Organometallic Compounds; Osteomyelitis; Oxyquinoline; Rad

1991
[The use of labelled leukocytes in the diagnosis of traumatic osteomyelitis].
    Meditsinskaia radiologiia, 1991, Volume: 36, Issue:3

    Topics: Adult; Aged; Female; Humans; Indium Radioisotopes; Leukocytes; Male; Middle Aged; Organometallic Com

1991
Unsuspected osteomyelitis in diabetic foot ulcers. Diagnosis and monitoring by leukocyte scanning with indium in 111 oxyquinoline.
    JAMA, 1991, Sep-04, Volume: 266, Issue:9

    Topics: Diabetes Mellitus, Type 2; Foot Diseases; Humans; Indium Radioisotopes; Leukocytes; Middle Aged; Mon

1991
99mTc-human immunoglobulin (HIG)--first results of a new agent for the localization of infection and inflammation.
    European journal of nuclear medicine, 1990, Volume: 16, Issue:8-10

    Topics: Bacterial Infections; Female; Fever of Unknown Origin; Humans; Immunoglobulins; Indium Radioisotopes

1990
Kinetic of Tc-99m-anti-NCA-95-Moab in vitro labelled granulocytes in comparison to in-vivo Moab-labelled and In-111-oxine-labelled granulocytes.
    Progress in clinical and biological research, 1990, Volume: 355

    Topics: Antibodies, Monoclonal; Cell Movement; Granulocytes; Hip Prosthesis; Humans; Indium Radioisotopes; K

1990
[Improved scintigraphic imaging using cell separator-enriched. indium-111-oxinate marked granulocytes].
    Beitrage zur Infusionstherapie = Contributions to infusion therapy, 1988, Volume: 21

    Topics: Crohn Disease; Granulocytes; Humans; Hydroxyquinolines; Leukapheresis; Leukocyte Count; Organometall

1988
[Rare generalized osteomyelitis].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 1988, Volume: 148, Issue:2

    Topics: Bone Marrow; Female; Humans; Indium Radioisotopes; Middle Aged; Organometallic Compounds; Osteomyeli

1988
Indium-111 leukocyte scintigraphic detection of subclinical osteomyelitis complicating delayed and nonunion long bone fractures: a prospective study.
    Journal of orthopaedic research : official publication of the Orthopaedic Research Society, 1987, Volume: 5, Issue:1

    Topics: Adult; Female; Fractures, Ununited; Humans; Hydroxyquinolines; Indium Radioisotopes; Leukocytes; Mal

1987
Cause and significance of cold bone defects on indium-111-labeled leukocyte imaging.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1987, Volume: 28, Issue:5

    Topics: Bone and Bones; Bone Diseases; Humans; Hydroxyquinolines; Indium Radioisotopes; Leukocytes; Organome

1987
Osteomyelitis complicating fracture: pitfalls of 111In leukocyte scintigraphy.
    AJR. American journal of roentgenology, 1987, Volume: 148, Issue:5

    Topics: Adult; False Positive Reactions; Follow-Up Studies; Fractures, Bone; Humans; Hydroxyquinolines; Indi

1987
[Diagnosis and follow-up of osteomyelitis of the jaw using 4-phase and labeled leukocyte scintigraphy].
    Fortschritte der Kiefer- und Gesichts-Chirurgie, 1987, Volume: 32

    Topics: Humans; Indium Radioisotopes; Jaw Diseases; Leukocytes; Organometallic Compounds; Osteomyelitis; Oxy

1987
[Place and significance of leukocyte scintigraphy of osteomyelitic processes in the jaw region].
    Fortschritte der Kiefer- und Gesichts-Chirurgie, 1987, Volume: 32

    Topics: Humans; Indium Radioisotopes; Jaw Diseases; Leukocytes; Male; Middle Aged; Organometallic Compounds;

1987
Indium-111 chloride scintigraphy in adult osteomyelitis.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1987, Volume: 28, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Indium; Leukocytes; Male; Middle Aged; Organometalli

1987
Diagnosis of infection by preoperative scintigraphy with indium-labeled white blood cells.
    The Journal of bone and joint surgery. American volume, 1987, Volume: 69, Issue:9

    Topics: Adult; Aged; Bacterial Infections; False Negative Reactions; False Positive Reactions; Female; Human

1987
[Technic and clinical use of radioactive labelling of autologous granulocytes].
    Wiener klinische Wochenschrift, 1988, Feb-05, Volume: 100, Issue:3

    Topics: Abscess; Aged; Bacterial Infections; Diagnosis, Differential; Female; Granulocytes; Humans; Hydroxyq

1988
99Tcm-labelled HSA-nanocolloid versus 111In oxine-labelled granulocytes in detecting skeletal septic process.
    Nuclear medicine communications, 1988, Volume: 9, Issue:1

    Topics: Female; Granulocytes; Hip Prosthesis; Humans; Hydroxyquinolines; Indium Radioisotopes; Intervertebra

1988
The effect of various antibiotics on the labelling efficiency of human white blood cells with 111In-oxine.
    Nuclear medicine communications, 1988, Volume: 9, Issue:8

    Topics: Adult; Aged; Anti-Bacterial Agents; Female; Humans; Hydroxyquinolines; Indium Radioisotopes; Isotope

1988
[Carrier systems for drugs--a new principle in drug therapy?].
    Deutsche medizinische Wochenschrift (1946), 1985, Jan-18, Volume: 110, Issue:3

    Topics: Blood Platelets; Drug Therapy; Erythrocyte Membrane; Erythrocytes; Humans; Kinetics; Liposomes; Macr

1985
Comparison of indium-labeled-leukocyte imaging with sequential technetium-gallium scanning in the diagnosis of low-grade musculoskeletal sepsis. A prospective study.
    The Journal of bone and joint surgery. American volume, 1985, Volume: 67, Issue:3

    Topics: Adolescent; Adult; Aged; Diphosphonates; Female; Gallium Radioisotopes; Humans; Hydroxyquinolines; I

1985
In-111 labeled leukocytes: a review of problems in image interpretation.
    Radiology, 1985, Volume: 155, Issue:1

    Topics: Abdomen; Abscess; Adult; Aged; Bacterial Infections; False Positive Reactions; Female; Humans; Indiu

1985