Page last updated: 2024-10-27

flucytosine and Osteomyelitis

flucytosine has been researched along with Osteomyelitis in 34 studies

Flucytosine: A fluorinated cytosine analog that is used as an antifungal agent.
flucytosine : An organofluorine compound that is cytosine that is substituted at position 5 by a fluorine. A prodrug for the antifungal 5-fluorouracil, it is used for the treatment of systemic fungal infections.

Osteomyelitis: INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.

Research Excerpts

ExcerptRelevanceReference
"A patient with thoracic cryptococcal osteomyelitis was treated successfully with the combination of fluconazole and flucytosine."7.71Successful treatment of cryptococcal osteomyelitis and paraspinous abscess with fluconazole and flucytosine. ( Cook, PP, 2001)
"Flucytosine is an antifungal drug which can also be given by mouth and carries relatively low toxicity."5.26Candida osteomyelitis as a complication of parenteral nutrition in an infant. Successful treatment with flucytosine. ( Berant, M; Kristal, C; Wagner, Y, 1979)
" lusitaniae osteomyelitis in whom treatment was successful with 5-fluorocytosine and fluconazole."4.78Candida lusitaniae osteomyelitis in a premature infant. ( Della-Latta, P; Oleinik, EM; Rinaldi, MG; Saiman, L, 1993)
"A patient with thoracic cryptococcal osteomyelitis was treated successfully with the combination of fluconazole and flucytosine."3.71Successful treatment of cryptococcal osteomyelitis and paraspinous abscess with fluconazole and flucytosine. ( Cook, PP, 2001)
"We report three cases of deep-seated and systemic Candida albicans infection in which inadequate dosages of fluconazole were used, leading to breakthrough fungaemia, candidal osteomyelitis and endocarditis."3.69Hazards of inadequate fluconazole dosage to treat deep-seated or systemic Candida albicans infection. ( Barnes, RA; Flanagan, PG, 1997)
"Cryptococcal osteomyelitis is extremely rare and almost always occurs in immunocompromised patients."1.38Cryptococcal osteomyelitis of the scapula and rib in an immunocompetent patient. ( Tang, ZH; Yu, YS; Zang, GQ; Zhang, Y, 2012)
"Treatment with amphotericin B (1000 mg total dose) and oral 5-fluorocytosine, resulted in complete recovery and resolution of the chest X-ray findings with a follow-up of 2 years."1.29Cryptococcus neoformans vertebral osteomyelitis. ( Block, C; Farfel, Z; Goldschmied-Reuven, A; Gurevitz, O; Hassin, D; Kopolovic, J, 1994)
"The spondylitis was probably superinfected with Staphylococcus aureus."1.27Hematogenous Candida spondylitis. A case report. ( Pohjola-Sintonen, S; Ruutu, P; Tallroth, K, 1984)
"Skeletal cryptococcosis is an uncommon infection."1.27Spastic paraparesis due to cryptococcal osteomyelitis. A case report. ( Matsushita, T; Suzuki, K, 1985)
"Flucytosine is an antifungal drug which can also be given by mouth and carries relatively low toxicity."1.26Candida osteomyelitis as a complication of parenteral nutrition in an infant. Successful treatment with flucytosine. ( Berant, M; Kristal, C; Wagner, Y, 1979)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-199017 (50.00)18.7374
1990's7 (20.59)18.2507
2000's5 (14.71)29.6817
2010's5 (14.71)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Poenaru, SM1
Rofaiel, R1
Hosseini-Moghaddam, SM1
Wang, J1
Ju, HZ1
Yang, MF1
Molter, CM1
Zuba, JR1
Papendick, R1
Zhang, Y1
Yu, YS1
Tang, ZH1
Zang, GQ1
Nankeu, S1
Djaha, JM1
Saint Marcoux, B1
Kaci, R1
Debandt, M1
Maliner, LI1
Kirby, A1
Hassan, I1
Burnie, J1
Pohjola-Sintonen, S1
Ruutu, P1
Tallroth, K1
Ward, RM1
Sattler, FR1
Dalton, AS1
Shaikh, BS1
Appelbaum, PC1
Aber, RC1
Hammerschlag, MR1
Domingo, J1
Haller, JO1
Papayanopulos, D1
Gurevitz, O1
Goldschmied-Reuven, A1
Block, C1
Kopolovic, J1
Farfel, Z1
Hassin, D1
Oleinik, EM1
Della-Latta, P1
Rinaldi, MG1
Saiman, L1
Flanagan, PG1
Barnes, RA1
Abu Jawdeh, L1
Haidar, R1
Bitar, F1
Mroueh, S1
Akel, S1
Nuwayri-Salti, N1
Dbaibo, GS1
Bielorai, B1
Toren, A1
Wolach, B1
Mandel, M1
Golan, H1
Neumann, Y1
Kaplinisky, C1
Weintraub, M1
Keller, N1
Amariglio, N1
Paswell, J1
Rechavi, G1
Cook, PP1
Berant, M1
Kristal, C1
Wagner, Y1
Lertratanakul, Y1
Glassford, GH1
Rubinstein, HM1
Svirsky-Fein, S1
Langer, L1
Milbauer, B1
Khermosh, O1
Rubinstein, E1
Poliner, JR1
Wilkins, EB1
Fernald, GW1
Businco, L1
Iannaccone, G1
Lucarelli, S1
Cardi, E1
Del Principe, D1
Rezza, E1
Thomas, FE1
Martin, CE1
Fisher, RD1
Alford, RH1
Sorensen, RU1
Boehm, KD1
Kaplan, D1
Berger, M1
Govender, S1
Rajoo, R1
Goga, IE1
Charles, RW1
Koppang, HS1
Olsen, I1
Stuge, U1
Sandven, P1
Flynn, PM1
Magill, HL1
Jenkins, JJ1
Pearson, T1
Crist, WM1
Hughes, WT1
Baldwin, S1
Stagno, S1
Odrezin, GT1
Kelly, DR1
Whitley, RJ1
Matsushita, T1
Suzuki, K1
Barnwell, PA1
Jelsma, LF1
Raff, MJ1
Freeman, JB1
Wienke, JW1
Soper, RT1
Hill, HR1
Mitchell, TG1
Matsen, JM1
Quie, PG1
Chmel, H1
Grieco, MH1
Zickel, R1
Nathan, CF1

Reviews

2 reviews available for flucytosine and Osteomyelitis

ArticleYear
Recommendations for managing Aspergillus osteomyelitis and joint infections based on a review of the literature.
    The Journal of infection, 2006, Volume: 52, Issue:6

    Topics: Amphotericin B; Antifungal Agents; Arthritis, Infectious; Aspergillosis; Aspergillus; Disease Manage

2006
Candida lusitaniae osteomyelitis in a premature infant.
    American journal of perinatology, 1993, Volume: 10, Issue:4

    Topics: Candidiasis; Diseases in Twins; Fluconazole; Flucytosine; Humans; Infant, Newborn; Infant, Premature

1993

Other Studies

32 other studies available for flucytosine and Osteomyelitis

ArticleYear
    BMJ case reports, 2017, Oct-11, Volume: 2017

    Topics: Abscess; Acute Kidney Injury; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Flucytosin

2017
Pulmonary cryptococcosis and cryptococcal osteomyelitis mimicking primary and metastatic lung cancer in (18)F-FDG PET/CT.
    International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases, 2014, Volume: 18

    Topics: Adult; Amphotericin B; Cryptococcosis; Cryptococcus neoformans; Female; Flucytosine; Fluorodeoxygluc

2014
Cryptococcus gattii osteomyelitis and compounded itraconazole treatment failure in a Pesquet's parrot (Psittrichas fulgidus).
    Journal of zoo and wildlife medicine : official publication of the American Association of Zoo Veterinarians, 2014, Volume: 45, Issue:1

    Topics: Animals; Antifungal Agents; Bird Diseases; Cryptococcosis; Cryptococcus gattii; Drug Compounding; Fe

2014
Cryptococcal osteomyelitis of the scapula and rib in an immunocompetent patient.
    Medical mycology, 2012, Volume: 50, Issue:7

    Topics: Amphotericin B; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Deoxycholic Acid; Drug C

2012
Disseminated cryptococcosis revealed by vertebral osteomyelitis in an immunocompetent patient.
    Joint bone spine, 2012, Volume: 79, Issue:6

    Topics: Adult; Amphotericin B; Antifungal Agents; Biopsy; Cryptococcosis; Cryptococcus neoformans; Flucytosi

2012
Successful treatment of cryptococcal osteomyelitis and paraspinous abscess.
    Southern medical journal, 2002, Volume: 95, Issue:8

    Topics: Abscess; Antifungal Agents; Cryptococcosis; Fluconazole; Flucytosine; Humans; Osteomyelitis; Thoraci

2002
Hematogenous Candida spondylitis. A case report.
    Acta medica Scandinavica, 1984, Volume: 215, Issue:1

    Topics: Amphotericin B; Candidiasis; Clindamycin; Drug Therapy, Combination; Female; Flucytosine; Humans; Ke

1984
Assessment of antifungal therapy in an 800-gram infant with candidal arthritis and osteomyelitis.
    Pediatrics, 1983, Volume: 72, Issue:2

    Topics: Amphotericin B; Arthritis, Infectious; Candidiasis; Cytosine; Drug Therapy, Combination; Female; Flu

1983
Vertebral disc space infection and osteomyelitis due to Candida albicans in a patient with acute myelomonocytic leukemia.
    Cancer, 1980, Mar-01, Volume: 45, Issue:5

    Topics: Aged; Amphotericin B; Candidiasis; Flucytosine; Humans; Intervertebral Disc; Leukemia, Myeloid, Acut

1980
Cryptococcal osteomyelitis. Report of a case amd a review of the literature.
    Clinical pediatrics, 1982, Volume: 21, Issue:2

    Topics: Amphotericin B; Child; Cryptococcosis; Female; Flucytosine; Humans; Osteomyelitis

1982
Cryptococcus neoformans vertebral osteomyelitis.
    Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology, 1994, Volume: 32, Issue:4

    Topics: Aged; Amphotericin B; Antigens, Fungal; Biopsy; Cryptococcosis; Cryptococcus neoformans; Drug Therap

1994
Hazards of inadequate fluconazole dosage to treat deep-seated or systemic Candida albicans infection.
    The Journal of infection, 1997, Volume: 35, Issue:3

    Topics: Adult; Aged; Amphotericin B; Amputation, Surgical; Antifungal Agents; Arthrodesis; Candidiasis; Dipl

1997
Aspergillus vertebral osteomyelitis in a child with a primary monocyte killing defect: response to GM-CSF therapy.
    The Journal of infection, 2000, Volume: 41, Issue:1

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Aspergillus; Biopsy, Needle; Child, Preschool; Flu

2000
Successful treatment of invasive aspergillosis in chronic granulomatous disease by granulocyte transfusions followed by peripheral blood stem cell transplantation.
    Bone marrow transplantation, 2000, Volume: 26, Issue:9

    Topics: Amphotericin B; Antifungal Agents; Aspergillosis; Child, Preschool; Combined Modality Therapy; Drug

2000
Successful treatment of cryptococcal osteomyelitis and paraspinous abscess with fluconazole and flucytosine.
    Southern medical journal, 2001, Volume: 94, Issue:9

    Topics: Abscess; Adult; Antifungal Agents; Cryptococcosis; Drug Therapy, Combination; Female; Fluconazole; F

2001
Candida osteomyelitis as a complication of parenteral nutrition in an infant. Successful treatment with flucytosine.
    Helvetica paediatrica acta, 1979, Volume: 34, Issue:2

    Topics: Administration, Oral; Candidiasis; Cytosine; Drug Evaluation; Flucytosine; Humans; Infant; Infant Nu

1979
Arthritis and osteomyelitis due to Candida albicans: a case report.
    The Journal of rheumatology, 1977,Autumn, Volume: 4, Issue:3

    Topics: Administration, Oral; Adult; Amphotericin B; Arthritis, Infectious; Candida albicans; Candidiasis; F

1977
Neonatal osteomyelitis caused by Candida tropicalis. Report of two cases and review of the literature.
    The Journal of bone and joint surgery. American volume, 1979, Volume: 61, Issue:3

    Topics: Amphotericin B; Arthritis, Infectious; Bone Development; Candidiasis; Femur; Flucytosine; Follow-Up

1979
Localized osseous cryptococcosis.
    The Journal of pediatrics, 1979, Volume: 94, Issue:4

    Topics: Amphotericin B; Cervical Vertebrae; Cryptococcosis; Flucytosine; Humans; Infant; Male; Osteomyelitis

1979
[Arthritis and disseminated osteitis caused by Candida albicans in a 2-month-old infant fed parenterally].
    Minerva pediatrica, 1976, Apr-28, Volume: 28, Issue:15

    Topics: Arthritis, Infectious; Candidiasis; Female; Flucytosine; Humans; Infant; Infant Nutritional Physiolo

1976
Candida albicans infection of sternum and costal cartilages: combined operative treatment and drug therapy and 5-fluorocytosine.
    The Annals of thoracic surgery, 1977, Volume: 23, Issue:2

    Topics: Candidiasis; Cartilage, Articular; Debridement; Flucytosine; Humans; Immunity, Cellular; Male; Middl

1977
Cryptococcal osteomyelitis and cellular immunodeficiency associated with interleukin-2 deficiency.
    The Journal of pediatrics, 1992, Volume: 121, Issue:6

    Topics: Adolescent; Amphotericin B; Cryptococcosis; Drug Therapy, Combination; Flucytosine; HLA Antigens; Hu

1992
Aspergillus osteomyelitis of the spine.
    Spine, 1991, Volume: 16, Issue:7

    Topics: Adult; Amphotericin B; Aspergillosis; Aspergillus fumigatus; Flucytosine; Humans; Male; Middle Aged;

1991
Aureobasidium infection of the jaw.
    Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology, 1991, Volume: 20, Issue:4

    Topics: Adult; Flucytosine; Humans; Male; Mandibular Diseases; Mitosporic Fungi; Molar, Third; Mycoses; Oste

1991
Aspergillus osteomyelitis in a child treated for acute lymphoblastic leukemia.
    The Pediatric infectious disease journal, 1990, Volume: 9, Issue:10

    Topics: Amphotericin B; Aspergillosis; Child; Femur; Flucytosine; Humans; Male; Osteomyelitis; Precursor Cel

1990
Isolated Cryptococcus neoformans osteomyelitis in an immunocompetent child.
    The Pediatric infectious disease journal, 1988, Volume: 7, Issue:4

    Topics: Amphotericin B; Child; Cryptococcosis; Drug Therapy, Combination; Female; Flucytosine; Humans; Ilium

1988
Spastic paraparesis due to cryptococcal osteomyelitis. A case report.
    Clinical orthopaedics and related research, 1985, Issue:196

    Topics: Amphotericin B; Combined Modality Therapy; Cryptococcosis; Flucytosine; Humans; Male; Middle Aged; M

1985
Aspergillus osteomyelitis. Report of a case and review of the literature.
    Diagnostic microbiology and infectious disease, 1985, Volume: 3, Issue:6

    Topics: Adult; Amphotericin B; Aspergillosis; Drug Therapy, Combination; Flucytosine; Humans; Male; Osteomye

1985
Candida osteomyelitis associated with intravenous alimentation.
    Journal of pediatric surgery, 1974, Volume: 9, Issue:5

    Topics: Candida albicans; Candidiasis; Flucytosine; Humans; Infant, Newborn; Infant, Newborn, Diseases; Knee

1974
Recovery from disseminated candidiasis in a premature neonate.
    Pediatrics, 1974, Volume: 53, Issue:5

    Topics: Amphotericin B; Antifungal Agents; Arthritis, Infectious; Candidiasis; Cytosine; Drug Resistance, Mi

1974
Candida osteomyelitis. Report of a case.
    The American journal of the medical sciences, 1973, Volume: 266, Issue:4

    Topics: Candida albicans; Flucytosine; Humans; Male; Middle Aged; Osteomyelitis; Oxacillin; Staphylococcus;

1973
Cryptococcal osteomyelitis treated with 5-fluorocytosine.
    The American review of respiratory disease, 1974, Volume: 110, Issue:1

    Topics: Aged; Antifungal Agents; Cryptococcosis; Cryptococcus neoformans; Curettage; Cytosine; Female; Flucy

1974