cmx-001 has been researched along with Osteomyelitis* in 1 studies
1 other study(ies) available for cmx-001 and Osteomyelitis
| Article | Year |
|---|---|
Successful Brincidofovir Treatment of Metagenomics-detected Adenovirus Infection in a Severely Ill Signal Transducer and Activator of Transcription-1-deficient Patient.
A signal transducer and activator of transcription-1-deficient patient presented with prolonged fever, cachexia, anemia, hypoalbuminemia and finally relapsing debilitating mycobacterial osteomyelitis while receiving a previously effective antimycobacterial treatment. Progression despite rigorous workup and multiple antibiotics prompted shotgun metagenomics revealing adenovirus in liver samples. Brincidofovir led to a complete, sustained clinical recovery, including osteomyelitis, probably attributed to reversal of adenovirus-induced immune dysregulation. Topics: Adenoviridae Infections; Antiviral Agents; Cytosine; Humans; Immunocompromised Host; Liver; Male; Metagenomics; Organophosphonates; Osteomyelitis; STAT1 Transcription Factor; Treatment Outcome; Young Adult | 2019 |