fleroxacin has been researched along with Osteomyelitis in 4 studies
Fleroxacin: A broad-spectrum antimicrobial fluoroquinolone. The drug strongly inhibits the DNA-supercoiling activity of DNA GYRASE.
fleroxacin : A fluoroquinolone antibiotic that is 4-oxo-1,4-dihydroquinoline which is substituted at positions 1, 3, 6, 7 and 8 by 2-fluoroethyl, carboxy, fluoro, 4-methylpiperazin-1-yl and fluoro groups, respectively. It is active against many Gram-positive and Gram-negative bacteria.
Osteomyelitis: INFLAMMATION of the bone as a result of infection. It may be caused by a variety of infectious agents, especially pyogenic (PUS - producing) BACTERIA.
| Excerpt | Relevance | Reference |
|---|---|---|
| " This multicenter study was designed to evaluate the efficacy and safety of oral fleroxacin in osteomyelitis and septic arthritis." | 5.07 | Efficacy of oral fleroxacin in bone and joint infections. ( Green, SL, 1993) |
| "The object of this open-label, noncomparative, multicenter study was to evaluate the efficacy and safety of 400 mg of fleroxacin administered orally once daily for 2-12 weeks to patients with bone and joint infections (osteomyelitis, septic arthritis, and prosthetic joint infection)." | 5.07 | A pilot study of oral fleroxacin given once daily in patients with bone and joint infections. ( Putz, PA, 1993) |
| "The objective of this open label, non-comparative study was to evaluate the efficacy and safety of fleroxacin 400mg administered orally once daily to patients with acute osteomyelitis and/or acute septic arthritis." | 5.07 | Clinical evaluation of fleroxacin in the treatment of bone and joint infections. ( Chen, YS; Cheng, DL; de Garis, ST; Hsieh, TL; Lin, HH; Liu, CY; Liu, YC; Wang, RS; Yen, MY, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (100.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Cutler, NR | 1 |
| Seifert, RD | 1 |
| Sramek, JJ | 1 |
| Boyd, WM | 1 |
| St Clair, P | 1 |
| Green, SL | 1 |
| Putz, PA | 1 |
| Liu, YC | 1 |
| Cheng, DL | 1 |
| Liu, CY | 1 |
| de Garis, ST | 1 |
| Lin, HH | 1 |
| Hsieh, TL | 1 |
| Yen, MY | 1 |
| Wang, RS | 1 |
| Chen, YS | 1 |
4 trials available for fleroxacin and Osteomyelitis
| Article | Year |
|---|---|
Fleroxacin treatment of stage IV pressure ulcers with associated osteomyelitis.
Topics: Aged; Aged, 80 and over; Female; Fleroxacin; Humans; Male; Osteomyelitis; Pressure Ulcer | 1994 |
Efficacy of oral fleroxacin in bone and joint infections.
Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Arthritis, Infectious; Female; Fleroxacin; Hum | 1993 |
A pilot study of oral fleroxacin given once daily in patients with bone and joint infections.
Topics: Administration, Oral; Adolescent; Adult; Aged; Aged, 80 and over; Arthritis, Infectious; Drug Admini | 1993 |
Clinical evaluation of fleroxacin in the treatment of bone and joint infections.
Topics: Acute Disease; Adult; Aged; Arthritis, Infectious; Bacteremia; Female; Fleroxacin; Humans; Male; Mid | 1992 |